@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs2129: (2015-12-13 )
MSKKIKNFILLNIGSLIVAFGFNAFFLHNHIVTGGISGLAVSFHEVFGWDSAFFIMIINIPLLLLCYFGLGKQTFLKTVYGSWIFPVFIKLTQSVPTLTHNPLLAALFGGVIVGCGLGIVFWSDSSTGGTGIIIQFLGKYTPISLGQGVILIDGLVTIVGFLAFDSDTVMFSIIGLITISYIINAIQTGFTTLSTVLIVSQEHQKIKTYINTVADRGVTEIPVKGGYSGTNQIMLMTTIAGYEFAKLQEAIAEIDETAFITVTPTSQASGRGFSLQKNHGRLDEDILMPM
Atome Classification :
(20 SA)
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.....---....10..--......20..----......-30........40........50........--60.......-.70........80........90........100.....--------------..--110.......120.......130...-------....140.......150--..----.....160------........170..----.....180.......190..------..-----...200-.--.---------...-...210-...--....220-.--...--.-.-------.--------.---------------230--------------....-.....240........250-.-..----.-----.--.-.260......-.270.......280.......290----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSKKI---
K
N
F
I
L
L
N
I
--
G
S
L
I
V
A
FG
F
N
----
A
F
F
L
HN-
H
I
VTGGIS
G
L
A
V
S
F
H
E
VFGWD
S
A
F
F
I
M
I
I
N
--
I
P
L
L
L
L
C
Y
F-GL
G
K
Q
T
F
L
K
T
V
Y
GS
W
I
F
P
V
F
I
K
L
T
Q
SVPTLTH
N
P
L
L
A
A
L
--------------
F
G
--
G
V
I
V
GCG
L
G
I
V
F
WSDSSTGG
T
G
I
I
I
Q
-------
F
LGKYTPISLG
Q
G
V
I
L
I--D
G
----
L
V
T
I
V
G
F
-------
L
AFDS
D
T
V
M
F
S
I
I
----
G
L
I
T
I
S
Y
I
I
N
A
I
Q
T
G
F
T
T
L
S
------
T
V
-----
L
I
V
SQ--
E
--
H
---------
Q
K
I
-
K
T
Y
I
N
T
-
V
A
D--RGVTEI--P--VKG--G-Y-------S--------G---------------T----------------
N
Q
I
M
-
L
M
T
TIA-G
Y
E
F
A
K
L
Q
E
A
I
A
-E-ID----E-----
T
--
A
-
F
I
T
VTPTSQA-SGRGFSLQKNHGRL
D
E
D
ILMPM------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
Fugue
74.95
15%
-154
- C1 -
4AV9
3
HSV2_KLULA
A:
[14-338]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
N
P
I
---
V
D
Y
E
F
N
Q
D
--
Q
S
C
L
I
V
S
T
P
K
----
S
F
D
I
Y
N
V
H
P
L
K
R
I
M
S
Q
E
M
P
D
A
G
T
I
R
M
L
H
R
T
N
Y
I
A
F
V
S
--
T
K
K
E
L
L
H
I
W
D
D
V
K
K
Q
D
I
T
R
V
K
L
D
A
A
V
K
D
L
F
L
--
S
R
E
F
I
V
V
S
Q
G
D
V
I
S
I
F
K
FGNPWNKITEDIK
F
G
--
G
V
-
C
E
F
A
N
G
L
L
V
Y
S
N
E
F
N
L
G
-
Q
I
H
V
T
-------
R
L
Q
T
D
A
E
Q
V
V
G
K
G
V
L
V
K
AH
A
N
----
P
V
K
M
V
R
L
N
RKGD
M
V
A
T
C
S
Q
D
G
T
L
I
R
V
F
Q
TDN
G
V
L
V
R
E
F
R
R
G
L
D
R
T
S
I
I
D
M
R
W
S
PDGS
K
L
-----
A
V
V
S
D
----------------
K
W
-
T
L
H
V
F
E
-
V
F
N
--
D
A
E
N
K
R
--
H
--
V
L
K
--
D
-
W
-------
I
--------
N
---------------
S
----------------
E
W
S
I
-
C
N
F
K
L
K
-
V
S
K
G
S
N
-
D
C
K
I
A
-
W
-
I
S
----
D
-----
T
--
G
-
L
V
I
V
W
P
N
R
R
--
L
A
D
T
F
K
L
N
Y
N
D
D
E
H
V
W
W
L
Q
L
N
Q
R
N
E
IP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
Fugue
63.80
15%
-129
- C3 -
1POI
1
GCTA_ACIFV
A:
[1-317]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
V
MT
L
K
D
A
I
A
K
Y
V
HS
G
D
H
I
A
L
G
G
F
T
TDRK
P
Y
A
A
V
F
-
E
I
L
R
Q
G
I
T
D
L
T
G
L
G
G
A
A
G
---
G
D
W
D
M
L
I
G
N
GR
V
K
A
Y
I
N
C
Y
T
-
A
N
S
G
V
T
N
V
S
R
R
F
R
K
W
F
E
A
G
K
L
T
M
E
D
Y
S
Q
D
V
I
Y
M
M
W
H
A
A
A
--------------
L
G
LP
F
L
P
V
T
L
M
Q
G
S
G
L
T
D
E
W
G
I
S
K
E
V
R
K
T
L
DKVPDDK
F
K
Y
I
D
N
P
F
K
P
G
E
K
V
V
A
V
--
P
V
P
Q
V
D
V
A
I
I
H
A
Q
-------
Q
A
S
P
D
G
T
V
R
I
W
G
G
-----
K
F
Q
D
V
D
I
A
E
A
A
K
Y
T
I
V
T
C
E
------
E
I
I
S
D
E
E
I
R
R
D
P
--
T
--
K
---------
N
D
I
P
G
M
C
V
D
A
-
V
V
L
--
A
P
Y
G
A
H
--
P
S
Q
C
Y
G
--
L
-
Y
-------
D
--------
Y
---------------
D
----------------
N
P
F
L
-
K
V
Y
D
K
V
-
S
K
T
Q
E
D
F
D
A
F
C
K
-
E
W
V
F
----
D
-----
L
--
K
-
D
H
D
E
Y
L
N
K
L
G
-
A
T
R
L
I
N
L
K
V
V
P
G
L
G
Y
H
I
D
M
T
K
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
Fugue
59.03
20%
-96
- C2 -
3QMZ
-
DYHC_YEAST
A:
[1364-4092]
E
F
V
I
E
K
S
L
N
R
I
K
K
F
W
K
E
A
QE
H
S
S
G
LK
L
V
R
E
WD
V
L
E
Q
A
C
K
E
D
L
E
E
L
V
S
M
K
A
SNYYK
I
F
E
Q
D
C
L
D
L
E
S
K
L
T
K
L
S
E
I
Q
V
N
W
V
E
V
Q
F
Y
W
L
D
L
Y
G
I
L
G
E
N
L
D
I
Q
NFLPLETSKFK
S
L
T
S
E
Y
K
M
I
T
T
R
A
F
Q
L
DTTIEVIH
I
P
N
F
D
T
T
L
K
L
T
I
D
S
L
K
M
I
K
S
S
L
S
T
F
L
E
R
Q
R
RD
D
L
L
K
I
I
GSG
K
H
H
D
Q
V
S
K
F
M
K
K
M
F
G
SDFITGVRSVEA
Q
E
W
L
N
I
L
D
T
E
I
K
L
S
V
F
T
Q
F
R
D
C
L
G
Q
L
K
D
GTDI
E
V
V
V
S
K
Y
I
---
F
Q
A
I
L
L
S
A
--
Q
V
M
W
T
E
L
V
E
K
----
C
--
K
Y
W
-
K
E
V
D
M
K
I
K
G
L
L
D
K
L
N
K
S
D
N
V
K
K
K
I
E
A
L
L
V
E
-----
Y
L
H
F
N
N
-
V
I
G
Q
R
L
L
W
A
K
V
Q
K
F
Y
L
N
S
V
F
I
S
Q
S
G
Y
L
L
L
I
G
F
A
T
L
T
D
S
L
--------------
H
Q
--
K
------
Y
G
G
C
F
F
G
P
A
G
T
G
K
T
E
T
V
K
A
-------
F
-----
G
Q
N
L
G
R
V
V
V
V
F
--
N
C
----
D
D
S
-------------
F
D
Y
Q
V
L
S
R
L
L
V
----
G
I
T
Q
I
G
A
W
G
C
F
D
E
F
N
R
L
D
E
K
------
V
L
-----
S
A
V
S
A
--
N
--
I
---------
Q
Q
I
-
Q
N
G
L
Q
V
-------
G
K
S
H
I
--
T
--
L
L
E
--
E
-
E
-------
T
--------
P
---------------
L
----------------
S
P
--------------------------
H
----
T
-----
A
--
V
-
F
I
T
L
L
P
E
N
L
K
K
S
F
R
E
F
S
M
K
S
Q
S
G
T
I
A
E
M
I
L
Q
I
M
G
FEDS
K
S
L
A
S
K
I
V
H
F
L
E
L
L
S
S
K
CSSMNHYHFG
L
R
T
L
K
G
V
L
R
N
C
S
P
L
ISEFGE
G
E
K
T
V
V
E
S
L
K
R
V
ILPSLGDTDEL
V
F
K
D
E
L
S
KS
K
A
I
V
Q
C
L
K
D
A
GE
E
F
L
K
K
C
M
Q
F
Y
Y
M
Q
KTQ
Q
A
L
I
L
V
G
K
AGCGKT
A
T
W
K
T
V
I
D
A
M
A
I
F
DGHA
N
V
V
Y
V
IDTKVLTKESLYGSMLKATLEW
R
D
G
L
F
T
S
I
L
R
R
V
N
D
D
ITGTFKN
S
R
I
W
V
V
F
D
SDLDP
E
Y
V
E
A
M
N
S
VLDDNKGE
R
L
P
I
P
PN
F
R
I
L
F
E
TDNL
D
H
T
T
P
A
T
I
T
R
C
G
L
L
W
FS
S
K
I
D
H
L
L
N
K
S
Y
E
A
L
D
NKLSM
F
E
L
D
K
L
K
D
L
I
SDS
F
D
M
A
S
L
T
N
I
F
T
C
S
NVRT
F
N
K
L
E
T
A
V
Q
L
A
V
H
L
I
S
S
Y
R
Q
W
FQNLDDKSL
K
D
V
I
T
L
L
I
K
R
S
L
L
Y
A
L
A
GDSTGE
S
Q
R
A
F
I
Q
T
I
N
TYFGH
D
S
Q
E
L
S
DDKLSFSSFCSEIPSV
S
L
E
A
H
E
V
M
R
P
D
I
V
I
P
T
I
D
T
I
K
H
E
K
I
F
Y
D
LL
N
S
K
R
G
I
I
L
C
GPP
G
S
G
K
T
M
I
M
N
N
A
LRNS
S
L
Y
D
V
V
GINFSKD
T
T
T
E
H
I
L
S
A
L
H
RHTNYVI
K
N
L
V
L
F
CV
V
L
F
L
R
Q
L
M
E
K
Q
G
F
WKTP
E
N
K
W
VTIE
R
I
H
I
V
GACNPPTDPGRIPMSERFTRHAAIYP
S
G
K
S
L
S
Q
I
Y
E
I
YYKAIFKLV
P
E
F
R
S
Y
T
E
P
F
A
R
A
S
V
H
L
Y
N
E
C
K
A
R
YSTGLQSHYL
F
S
P
R
E
L
T
R
L
V
R
G
V
Y
T
A
I
NTGPRQTL
R
S
L
I
R
L
W
A
Y
E
A
W
R
I
FAVK
E
K
N
S
F
E
Q
L
L
Y
E
T
V
DKYL
P
N
Q
D
LG
N
I
S
S
TNK
T
D
L
V
N
F
I
E
E
R
F
K
T
F
C
D
EEP
M
V
I
H
E
S
M
V
D
H
I
L
R
I
D
R
A
LK
Q
V
Q
G
H
M
M
L
IGA
S
R
T
G
K
T
I
L
T
R
F
V
A
WL
N
G
L
K
I
V
Q
PKIHRHSNL
S
D
F
D
M
I
L
K
K
A
I
S
D
C
SLKES
R
T
C
L
I
I
DESNIL
E
T
A
F
L
E
R
M
N
T
L
L
ANDLFQG
E
E
Y
D
K
L
L
N
N
L
R
N
K
T
RD
T
E
Q
E
L
Y
D
W
F
V
G
E
I
A
K
N
L
H
V
V
F
T
I
CDPTNN
K
S
S
A
M
I
S
S
P
A
L
FNR
C
I
I
N
W
MT
K
T
M
S
Q
V
A
N
N
M
V
D
V
V
PMEFTDFI
V
P
E
V
N
K
E
L
V
F
T
E
P
I
Q
T
I
RDP
G
Y
F
I
D
GLR
A
L
V
K
L
V
T
A
K
Y
Q
D
L
Q
E
N
Q
R
F
V
N
V
G
L
E
K
L
N
E
S
VL
E
A
S
I
S
L
V
K
S
L
T
F
E
K
E
R
W
L
N
T
T
K
Q
F
S
K
T
S
Q
E
L
I
G
N
C
I
I
S
S
I
Y
E
T
Y
FGHLN
E
R
E
R
G
D
M
L
V
I
L
K
R
LLGKFAVKYDVNYRFIDYLV
T
L
D
E
K
M
K
WLECGY
F
L
E
N
M
S
I
V
M
N
S
QVPFLLDPS
S
H
M
I
T
V
I
S
NYYGNK
T
V
L
L
S
F
LEEG
F
V
K
R
L
E
N
A
V
R
FG
S
V
V
I
I
Q
D
G
E
F
F
D
P
I
I
S
R
L
I
S
R
E
FN
R
V
T
V
EI
G
D
H
E
VK
L
F
I
H
S
C
DPS
G
D
I
P
I
F
L
R
S
R
V
R
L
V
H
FVTS
I
E
T
R
I
F
D
I
T
L
T
E
E
N
A
E
M
Q
R
K
R
E
D
L
I
K
L
N
T
E
Y
R
L
K
L
K
N
L
E
K
R
L
L
E
E
L
N
ND
E
L
M
V
T
L
N
N
L
K
K
E
A
M
N
I
E
K
K
L
S
E
S
E
E
F
F
PQ
F
D
N
L
V
E
E
Y
S
I
I
G
K
H
S
V
K
I
F
S
M
L
E
K
F
G
QFHWFYGIS
I
G
Q
F
L
S
C
F
K
R
V
F
I
KTRA
A
R
T
R
V
D
E
I
L
W
L
L
Y
Q
EVYCQFST
A
L
D
K
K
F
K
M
I
M
AM
T
M
F
C
L
Y
K
F
D
IESEQLTVD
T
N
D
D
L
R
Y
L
W
D
Y
V
TTK
S
Y
I
S
A
L
N
W
FKNW
N
I
A
D
V
V
A
N
SE
N
N
Y
F
T
M
A
S
EDG
T
F
K
L
I
E
L
A
K
A
SKES
L
K
I
I
PLGSIEN
L
N
Y
A
Q
E
E
I
S
K
S
K
I
E
G
G
W
I
L
L
Q
NIQMSL
S
W
V
K
T
Y
L
H
K
H
V
E
ETKAAEEK
M
F
M
T
C
HLTG
D
K
L
P
APLLQRTD
R
V
V
Y
E
D
I
PGI
L
D
T
V
K
D
L
W
G
S
Q
F
FTGSGV
W
S
V
Y
C
T
F
L
L
S
W
F
H
A
L
I
T
A
RD
C
D
F
Q
F
A
S
V
Y
L
E
N
V
L
APWAQ
V
R
D
H
I
A
T
I
VYGGKIDEEK
D
L
E
V
V
A
K
L
C
A
H
VFCD
N
L
Q
I
V
P
G
V
RIPQPLLQQ
S
E
E
E
E
R
A
R
L
T
A
IADS
L
S
S
W
L
Q
LPRES
I
L
D
Y
E
R
L
Q
A
K
E
V
A
S
S
T
E
Q
L
L
Q
E
M
30
HHSearch
57.66
19%
-81
- C4 -
2DCL
2
Y1503_PYRHO
A:
[9-111]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
L
------
R
L
-----
R
I
Y
I
G
--
E
--
N
DKWEGRP
L
Y
K
V
I
-
V
E
K
L
R
E
-
M
G
I
--
A
G
A
T
V
Y
--
R
--
G
I
Y
--
G
-
F
-------
G
-------------------------T
D
--------------
L
P
I
I
-
V
E
V
V
D
R
-
G
H
N
I
E
K
V
V
N
V
I
K
-
P
-
M
I
----
K
-----
D
--
G
-
M
I
T
V
E
P
T
I
V
L
-
W
V
G
T
Q
E
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
57.65
18%
-90
- C4 -
3DFE
2
?
A:
[5-102]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
A
N
------
K
L
-----
V
I
V
T
E
--
K
VL
L
---------
K
K
V
-
A
K
I
I
E
E
-
A
G
A
--
T
G
Y
T
V
V
--
D
--
T
G
G
------------------------------------------------------
S
N
V
K
-
F
E
V
L
T
E
N
R
E
M
A
E
K
I
A
D
Q
V
A
I
K
-
F
F
TD--
Y
-----
A
--
G
-
I
I
Y
I
C
E
A
E
V
L
-
Y
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
56.34
15%
-88
- C4 -
2EG2
2
GLNB_AQUAE
A:
[4-101]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
-----
E
A
I
I
K
PF
K
--
L
---------
D
E
V
-
K
D
A
L
V
E
-
I
G
I
--
G
G
M
T
V
T
--
E
--
V
K
G
--
F
-------------------D
F
-------------
L
----------------
P
K
V
K
-
I
E
V
V
V
R
-
D
E
D
V
E
K
V
V
E
T
I
V
-
K
-
T
A
----
Q
TGRVG
D
--
G
-
K
I
F
I
I
P
V
E
D
V
-
I
R
I
R
T
G
E
R
G
E
Q
A
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
55.75
18%
-86
- C4 -
2O66
2
GLNB_ARATH
A:
[13-114]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
Y
------
K
V
-----
E
A
I
V
R
--
P
WR
I
---------
Q
Q
V
-
S
S
A
L
L
K
-
I
G
I
--
R
G
V
T
V
S
--
D
--
V
R
G
--
F
-
G
-----------------ED
K
F
-----------
V
----------------
A
K
V
K
-
M
E
I
V
V
K
-
K
D
Q
V
E
S
V
I
N
T
I
I
-
E
-
G
A
----
R
TGEIG
D
--
G
-
K
I
F
V
L
P
V
S
D
V
-
I
R
V
R
T
G
E
R
G
E
K
A
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
55.55
13%
-98
- C4 -
2NS1
1
GLNK_ECOLI
B:
[5-106]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
------
L
V
-----
T
V
I
I
K
--
P
FK
L
---------
E
D
V
-
R
E
A
L
S
S
-
I
G
I
--
Q
G
L
T
V
T
--
E
--
V
K
G
--
F
-
G
-------
R
--------
Q
---------------
K
G
H
A
ELYRGAEFS
V
N
F
L
P
K
V
K
-
I
D
V
A
I
A
-
D
D
Q
L
D
E
V
I
D
I
V
S
-
K
-
A
A
----
Y
TGKIG
D
--
G
-
K
I
F
V
A
E
L
Q
R
V
-
I
R
I
R
T
G
E
A
D
E
A
A
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
55.41
18%
-80
- C4 -
1VFJ
-
?
A:
[4-115]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
-----
V
A
I
V
R
--
P
EK
L
---------
N
E
V
-
L
K
A
L
F
Q
-
A
E
V
--
R
G
L
T
L
S
--
R
--
V
Q
G
--
H
-
G
-------
G
--------
E
TER
V
E
T
Y
R
GTTVKME
L
----------------
H
E
K
V
R
L
E
I
G
V
S
-
E
P
F
V
K
P
T
V
E
A
I
L
-
K
-
A
A
----
R
TGEVG
D
--
G
-
K
I
F
V
L
P
V
E
K
V
-
Y
R
------
I
R
T
G
E
E
D
E
A
A
V
T
P
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
HHSearch
55.22
17%
-94
- C4 -
2GW8
-
?
A:
[3-101]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
-----
E
A
I
V
K
PF
K
--
L
---------
D
D
V
-
R
E
A
L
T
E
-
I
G
I
--
T
G
M
T
V
S
--
E
--
V
K
G
--
F
-
G
-------
R
VD------
F
---------------
L
----------------
P
K
I
K
-
I
E
L
V
L
A
-
D
D
A
V
E
R
A
I
D
V
I
V
-
E
-
V
A
----
R
SGKIG
D
--
G
-
K
I
F
V
L
P
V
E
E
A
-
I
R
I
R
T
G
E
R
S
D
A
A
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
54.76
19%
-75
- C4 -
2CZ4
3
?
A:
[24-116]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
L
K
------
L
V
-----
T
I
V
A
E
--
S
LL
E
---------
K
R
L
-
V
E
E
V
K
R
-
L
G
A
--
K
G
Y
T
I
T
--
P
--
A
R
G
--
E
-
G
-------
S
RGIRSVDW
E
---------------
G
----------------
Q
N
I
R
-
L
E
T
I
V
S
-
E
E
V
A
L
R
I
L
Q
R
L
Q
-
E
-
E
Y
----
F
PHY--
A
--
V
-
I
A
Y
V
E
N
V
W
V
V
-
R
G
E
K
Y
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
53.55
12%
-87
* C4 *
3NCQ
6
?
A:
[4-102]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
-----
E
A
I
V
R
AE
K
--
F
---------
P
E
V
-
K
A
A
L
E
E
-
R
G
F
--
Y
G
M
T
V
T
D
V
K
--
G
R
G
--
Q
-
Q
-------
G
--------
G
M
Q
I
Q
F
RGRTMEVTL-
L
----------------
P
K
V
K
-
L
E
I
V
V
K
-
D
D
A
V
E
E
V
I
G
L
I
V
-
N
-
S
A
----
F
TGSPG
D
--
G
-
K
I
F
I
I
P
V
E
D
V
-
V
R
I
R
T
G
E
R
G
D
D
S
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
53.08
13%
-87
- C4 -
3BZQ
-
GLNB_MYCTU
A:
[4-102]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
-----
T
A
I
V
K
PF
T
--
L
---------
D
D
V
-
K
T
S
L
E
D
-
A
G
V
--
L
G
M
T
V
S
--
E
--
I
Q
G
--
Y
-
G
-------
R
---------D
F
-------------
V
----------------
P
K
V
R
-
I
E
V
V
V
D
-
D
S
I
V
D
K
V
V
D
S
I
V
-
R
-
A
A
----
R
TGKI-
G
--
D
G
K
V
W
V
S
P
V
D
T
I
-
V
R
V
R
T
G
E
R
G
H
D
A
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
53.03
17%
-95
- C4 -
3T9Z
-
?
A:
[4-102]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-----
V
A
V
I
R
PE
K
--
L
---------
E
C
V
-
K
K
A
L
E
E
-
R
G
F
--
V
G
M
T
V
T
E
V
K
--
G
R
G
--------------------------------------L
L
--------------
Q
K
T
K
-
V
E
V
V
V
S
-
D
D
A
V
D
E
V
V
E
A
I
V
-
S
-
S
A
RTGK
F
-----
G
D-
G
-
R
I
F
V
I
P
V
E
K
S
-
V
K
I
R
T
G
D
E
E
V
A
A
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
HHSearch
52.01
12%
-78
- C4 -
3L7P
-
?
A:
[2-102]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
------
K
I
-----
E
A
I
I
R
--
S
DK
L
---------
E
D
L
-
K
A
A
L
V
--
Q
S
G
FI
K
G
M
T
I
S
--
Q
--
V
L
G
--
F
-
G
--------T-------
L
---------------
L
----------------
A
K
V
K
-
V
E
I
V
A
H
-
D
A
A
V
E
E
M
I
T
T
I
S
-
Q
-
A
V
----
K
TG------
G
-
K
I
F
V
S
P
V
D
E
I
-
V
R
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
HHSearch
51.22
14%
-68
- C4 -
2J9C
9
Y059_METJA
A:
[5-105]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
-----
E
A
I
I
R
PE
K
--
L
---------
E
I
V
-
K
K
A
L
S
D
-
A
G
Y
--
V
G
M
T
V
S
E
V
K
--
G
R
G
--
V
-
Q
GGI
V
E
R
Y
R
--------
G
R
E
Y
I
V
D
L
--------
I
----------------
P
K
V
K
-
I
E
L
V
V
K
-
E
E
D
V
D
N
V
I
D
I
I
C
-
E
-
N
A
----
R
TGNPG
D
--
G
-
K
I
F
V
I
P
V
E
R
V
-
V
R
V
R
T
K
E
E
G
K
E
A
L
L
E
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
49.89
13%
-87
- C4 -
3CE8
4
?
A:
[20-114]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
S
T
E
Q
------
L
L
-----
V
L
I
A
Q
--
N
DI
K
---------
D
D
I
-
V
D
T
L
I
E
L
E
F
L
--
S
G
F
S
L
G
--
N
--
I
C
G
F
S
R
E----------------------------------G
Y
R
-------------
E
F
C
K
-
F
E
I
M
H
P
-
A
A
Q
Q
A
A
L
L
T
A
L
A
-
L
-
V
C
----
K
-----
H
N
P
C
-
R
Y
W
I
M
P
I
Y
Q
N
-
G
T
L
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
HHSearch
49.29
14%
-85
- C4 -
1O51
3
Y021_THEMA
A:
[13-111]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
------
L
L
-----
K
I
Y
L
G
--
E
--
K
DKHSGKP
L
F
E
Y
L
-
V
K
R
A
Y
E
-
L
G
M
--
K
G
V
T
V
Y
--
R
--
G
I
M
--
G
-
F
-------
G
--------
H
----------------P
D
--------------
L
P
I
V
-
L
E
I
V
D
E
-
E
E
R
I
N
L
F
L
K
E
I
D
-
N
-
I
D
----
F
-----
D
--
G
-
L
V
F
T
A
D
V
N
V
V
-
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
HHSearch
46.52
16%
-44
- C4 -
1HWU
-
?
A:
[13-102]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
---------
D
E
V
-
R
E
S
L
A
E
-
V
G
V
--
T
G
L
T
V
T
--
E
--
V
K
G
--
F
-
G
-----------------YVV
D
F
----------
L
----------------
P
K
V
K
-
I
E
V
V
V
D
-
D
K
V
V
E
Q
A
V
D
A
I
I
-
K
-
A
A
----
R
TGKI-
G
--
D
G
K
I
F
V
Q
E
V
E
Q
V
-
I
R
I
R
T
G
E
T
G
P
D
A
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
42.62
14%
-14
- C4 -
3M05
3
?
A:
[18-68]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
---------
N
Y
L
-
S
D
Q
F
I
D
--
Q
N
--
V
R
A
T
K
L
--
S
--
T
T
G
--
G
-
F
-------
L
--------
Q
---------------
S
----------------
G
N
T
T
-
F
M
I
G
I
E
-
E
E
R
V
P
E
V
L
E
I
I
K
-
K
-
A
S
----
H
-----
T
--
R
-
E
E
F
M
T
P
Y
P
I
K
-
V
Q
V
G
G
A
T
V
L
V
L
P
V
D
Q
F
E
R
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------