@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu04780: (2016-06-08 )
METSALLKQQIAKEIGLSQKHVESVIRLLEDGNTVPFIARYRKEQTGSMDEVQIQTISERWQYIQNLNQRKEEVIRLIAEQDKLTDNLKRKIEQSVKLQEVEDLYRPYKQKRKTKATVAKSKGLEPLADYILTLPQDDHLAATADQYISEEKEVFTREEAIEGAKHIIAEQISDEPTFRKWIRQETFKRGTIKSAAGKSADTDEKNVYEMYYEYEEPIAKVVPHRVLAMNRGEKEDILKVAIEPPADHIKAYLEKQIIKNRSTSVREILQETIEDSYKRLIQPAIEREIRKELSEKADEQAIHIFSENLRKLLLQPPMKGKTVLGVDPAFRTGCKLAVSDETGKVLKIDVIYPHAPVNKTKEAHEKVKKILEQYQVEMVAIGNGTASRETEQFIVNVLRDMPRKIYYVIVNEAGASVYSASELAREEFPDLKVEERSAVSIARRLQDPLAELVKIDPKSVGVGQYQHDVSQKRLNESLRFVVETVVNQVGVNVNTASAALLQYVAGLSKSVAGNVVKKREEIGKFSNRKELKDIPRLGAKTYEQCIGFLRVQEGTEPLDRTGIHPESYKETKALLKKLGLSTEHIGTAELKDKINQLALSETAKELGIGEITLKDICEQLTRPERDPRDKVPKPLLKTDVLQLEDLKEGMELQGTVRNVVDFGAFVDIGVKQDGLVHISKLSNQFVKHPLDVVSVGDIVTVWVDGVDVQKGRVSLSMVK
Atome Classification :
(20 SA)
-----------------------------------------------.........10....--.------..--------.20........-30........40.......-------.50........60........70........80........90........100.......110.......120.......130..----------------------.....140-........150.......160.......170......----.180.......190---..--.....200.......210.......220--.......230......----.240.-.------...-..250-----..--....-..-----260--..-------.......270.......280.......290.......300.......310.......320.......330.-----------......340.......350....-...360.......370.......380.......390.......400-.-.---------.....410.......420.......430.......440.......450...---....460.......470.......480.......490....-----...500.......510.......520.-......530.......540.......550.....----..560.......570.....-..580..-----.-....590---.......600.......610.......620.......630.......640.......650.......660.......--670........680.......690.......700.......710-........-----
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------------------------M
E
T
S
A
L
L
K
Q
Q
I
A
K
E
I--G------L
S
--------
Q
K
H
V
E
S
V
I
R
L
L
-EDGNTV
P
F
I
A
R
Y
R
K
EQTGS-------M
D
E
V
Q
I
Q
T
I
S
E
R
W
Q
Y
I
Q
N
L
N
Q
R
K
E
E
V
I
R
L
I
A
E
Q
D
K
L
T
D
N
L
K
R
K
I
E
Q
SV
K
L
Q
E
V
E
D
L
Y
R
P
Y
K
Q
K
R
K
T
K
A
T
VAKSKG
L
E
P
L
A
D
Y
I
L
TL----------------------PQDDH
L
A
--
A
T
A
D
Q
Y
I
S
E
E
K
E
V
F
T
R
E
E
A
I
E
G
A
K
H
I
I
A
E
QISD
E
P
T
F
----
R
K
W
I
R
Q
E
T
FKRGTI---KS--AAGKSADTDE
K
N
V
Y
E
M
Y
Y
E
Y
EE
P
I
A
K
V
V
--
P
H
R
V
L
AMNRGEKE
D
I
L
----
K
V
AIE-P------
P
A
D
-
H
I
K
A
------
Y
L
--
E
K
Q
I
-
I
K-----N----RS-------
T
S
V
R
E
I
L
Q
E
T
I
E
D
S
Y
K
R
L
I
Q
P
A
I
E
R
E
I
R
K
E
L
S
E
KA
D
E
Q
A
I
H
I
F
S
E
N
L
R
K
L
L
LQPPMKG
K
T
V
LGVD
P
A
F
RTG-----------C
K
L
A
VSDETG
K
V
L
K
I
D
V
I
YPHAP-VN
K
T
K
E
A
H
E
K
V
K
K
I
L
E
QYQ
V
E
M
V
A
IGNGTAS
R
E
T
E
Q
F
I
V
N
V
L
RDMP-
R
-
K
---------
I
Y
Y
V
I
VNEAGASVY
S
A
S
E
L
A
R
E
EFPDLK
V
E
E
R
S
A
V
S
I
A
R
R
L
Q
D
P
L
A
E
L
V
KI---DPKSVGV
G
Q
Y
Q
H
D
V
S
Q
K
R
L
N
E
S
L
R
F
V
V
E
T
V
V
N
Q
VGVNV
N
T
A
-----
S
A
A
L
L
Q
Y
V
A
G
L
S
K
S
V
A
G
N
V
V
K
K
R
E
E
I
G
-KFS
N
R
K
E
L
K
D
I
P
R
L
G
A
K
T
Y
E
Q
C
I
G
F
L
R
VQEGTEP----LDRTGIH
P
E
S
Y
K
E
T
K
A
L
L
K
K-LGLSTEH-----I-
G
T
A
E
L
K
D
---
K
I
N
Q
L
A
L
S
E
T
A
K
ELGIG
E
I
T
L
K
D
I
C
E
Q
L
TRPERDPRDKVPK
P
L
L
K
T
D
V
L
Q
L
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D
L
KE
G
M
E
L
Q
G
T
V
R
N
V
VDFG
A
F
V
D
IG--V-KQDGL
V
H
I
S
K
L
S
N
Q
F
V
KHPL
D
V
VSVG
D
I
V
T
V
W
VDGVDVQKG--
R
V
S
L
SMVK-----
51
Fugue
81.89
42%
-94
- C4 -
3BZC
-
?
A:
[1-730]
--------------------------------------------------
M
D
S
I
N
T
R
I
A
E
E
L
--
S
A
LPSGR
V
Q
--------
P
Q
Q
V
A
A
A
V
A
L
L
-
D
E
G
S
T
V
P
F
I
A
R
Y
R
K
E
V
T
G
S
-------
L
D
D
T
Q
L
R
M
L
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R
L
R
Y
L
R
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L
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R
G
A
I
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A
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A
R
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L
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K
T
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L
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D
L
Y
L
P
Y
K
Q
K
R
R
T
K
G
Q
I
A
L
E
A
G
L
G
A
L
A
D
A
L
F
D
D
----------------------
P
T
L
V
-
P
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--
S
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A
A
R
F
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G
F
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A
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Y
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M
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F
A
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A
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L
----
L
D
K
L
R
V
F
M
K
N
E
A
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L
---
T
A
--
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V
V
P
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-
K
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A
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K
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S
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N
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----
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-
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EEAPG
T
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H
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P
C
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------
M
I
--
A
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R
F
G
L
S
-----
N
----
Q
G
-------
R
A
A
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K
W
L
A
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V
V
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W
T
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A
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L
L
A
A
P
A
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P
R
A
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L
G
L
D
P
G
L
R
T
G
-----------
V
K
V
A
V
V
D
A
T
G
K
L
L
D
T
A
T
V
Y
P
H
A
P
-
K
N
Q
W
D
Q
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L
A
V
L
A
A
L
C
A
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H
Q
V
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L
I
A
I
G
N
G
T
A
S
R
E
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D
K
L
A
G
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L
I
K
K
Y
P
-
G
M
K
---------
L
T
K
I
M
V
S
E
A
G
A
S
V
Y
S
A
S
E
L
A
A
K
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P
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L
R
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A
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A
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R
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Q
D
P
L
A
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L
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K
I
---
E
P
K
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I
G
V
G
Q
Y
Q
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L
K
L
A
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L
D
A
V
V
E
D
C
V
N
A
V
G
V
D
V
N
T
A
-----
S
A
A
L
L
A
R
I
S
G
L
N
S
T
L
A
Q
N
I
V
A
H
R
D
A
N
G
-
A
F
R
T
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D
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K
V
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R
L
G
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K
T
F
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Q
A
A
G
F
L
R
V
M
N
G
D
N
P
----
L
D
A
S
A
V
H
P
E
T
Y
P
L
V
Q
R
I
A
A
D
-
T
E
R
D
I
R
S
-----
L
I
G
D
S
A
F
L
K
---
R
L
D
P
K
K
F
T
D
E
----
T
F
G
L
P
T
V
T
D
I
L
K
E
L
D
K
P
G
R
D
P
R
P
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F
K
T
A
E
F
Q
E
G
V
E
S
L
K
D
L
K
P
G
M
V
L
E
G
V
V
T
N
V
T
N
F
G
A
F
V
D
I
G
--
V
-
H
Q
D
G
L
V
H
I
S
A
L
S
E
K
F
V
K
D
P
Y
E
V
V
K
A
G
D
I
V
K
V
K
V
M
E
V
D
I
P
R
N
--
R
V
G
L
S
M
R
M
SDTPG
22
HHSearch
80.27
42%
-93
- C4 -
3BZC
-
?
A:
[2-724]
---------------------------------------------------
D
S
I
N
T
R
I
A
E
E
L
--
S
A
LPSGR
V
Q
--------
P
Q
Q
V
A
A
A
V
A
L
L
-
D
E
G
S
T
V
P
F
I
A
R
Y
R
K
E
V
T
G
S
-------
L
D
D
T
Q
L
R
M
L
E
E
R
L
R
Y
L
R
E
L
E
E
R
R
G
A
I
L
A
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E
Q
G
K
L
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L
A
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D
I
K
L
A
D
T
K
T
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L
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D
L
Y
L
P
Y
K
Q
K
R
R
T
K
G
Q
I
A
L
E
A
G
L
G
A
L
A
D
A
L
F
D
D
----------------------
P
T
-
L
V
P
E
--
S
E
A
A
R
F
V
D
A
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K
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F
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K
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A
K
Y
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M
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R
F
A
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D
A
T
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----
L
D
K
L
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V
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M
K
N
E
A
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L
---
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A
--
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V
P
G
-
K
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Q
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A
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N
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----
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K
-
V
------
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A
P
G
T
LH
P
C
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M
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--
A
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L
-----
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NQGR
A
A
-------
D
K
W
L
---
A
E
V
V
R
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W
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T
G
-----------
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K
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A
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K
L
L
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T
A
T
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Y
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K
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A
S
R
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D
K
L
A
G
E
L
I
K
K
Y
P
G
M
-
K
---------
L
T
K
I
M
V
S
E
A
G
A
S
V
Y
S
A
S
E
L
A
A
K
E
F
P
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D
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L
R
G
A
V
S
I
A
R
R
L
Q
D
P
L
A
E
L
V
K
I
---
E
P
K
S
I
G
V
G
Q
Y
Q
H
D
V
S
Q
L
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L
A
R
S
L
D
A
V
V
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C
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N
A
V
G
V
D
V
N
T
A
-----
S
A
A
L
L
A
R
I
S
G
L
N
S
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L
A
Q
N
I
V
A
H
R
D
A
N
G
-
A
F
R
T
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L
K
K
V
S
R
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G
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K
T
F
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Q
A
A
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F
L
R
V
M
N
G
D
N
P
----
L
D
A
S
A
V
H
P
E
T
Y
P
L
V
Q
R
I
A
A
D
-
T
E
R
D
I
R
S
-----
L
-
I
--
G
D
S
A
---
F
L
K
R
L
D
P
K
K
F
T
D
E
-
T
F
G
L
P
T
V
T
D
I
L
K
E
L
D
K
P
G
R
D
P
R
P
E
F
K
T
A
E
F
Q
E
G
V
E
S
L
K
D
L
K
P
G
M
V
L
E
G
V
V
T
N
V
T
N
F
G
A
F
V
D
I
G
--
V
-
H
Q
D
G
L
V
H
I
S
A
L
S
E
K
F
V
K
D
P
Y
E
V
V
K
A
G
D
I
V
K
V
K
V
M
E
V
D
I
P
R
N
--
R
V
G
L
S
M
R
------
2
PsiBlast_PDB
79.34
43%
-93
- C4 -
3BZC
-
?
A:
[23-723]
----------------------------------------------------------------------------------
Q
Q
V
A
A
A
V
A
L
L
-
D
E
G
S
T
V
P
F
I
A
R
Y
R
K
E
V
T
G
S
-------
L
D
D
T
Q
L
R
M
L
E
E
R
L
R
Y
L
R
E
L
E
E
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R
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A
I
L
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G
K
L
T
P
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L
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I
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L
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L
Y
L
P
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Q
K
R
R
T
K
G
Q
I
A
L
E
A
G
L
G
A
L
A
D
A
L
F
-------------------------
D
D
P
T
L
V
P
E
S
E
A
A
R
F
V
D
A
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K
G
F
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L
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L
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M
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N
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A
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--
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A
---
R
V
--
V
P
G
K
E
---
Q
E
G
A
K
F
S
D
Y
F
E
H
D
E
P
L
K
S
A
P
--
S
H
R
A
L
A
I
F
R
G
R
N
E
G
V
L
S
A
S
L
K
V
G
E
E
-
A
------
P
G
T
L
H
P
C
E
------
V
M
I
A
E
R
F
G
-
L
S
-----
N
----
Q
G
-------
R
A
A
D
K
W
L
A
E
V
V
R
W
T
W
K
V
K
L
Y
T
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L
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L
F
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L
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A
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L
H
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L
L
L
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A
P
A
G
P
R
A
T
L
G
L
D
P
G
L
R
T
G
-----------
V
K
V
A
V
V
D
A
T
G
K
L
L
D
T
A
T
V
Y
P
H
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L
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N
G
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A
S
R
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T
D
K
L
A
G
E
L
I
K
K
Y
P
G
M
-
K
---------
L
T
K
I
M
V
S
E
A
G
A
S
V
Y
S
A
S
E
L
A
A
K
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F
P
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L
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L
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A
V
S
I
A
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L
Q
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P
L
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L
V
K
I
---
E
P
K
S
I
G
V
G
Q
Y
Q
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Q
L
K
L
A
R
S
L
D
A
V
V
E
D
C
V
N
A
V
G
V
D
V
N
T
A
-----
S
A
A
L
L
A
R
I
S
G
L
N
S
T
L
A
Q
N
I
V
A
H
R
D
A
N
G
-
A
F
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T
R
D
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L
K
K
V
S
R
L
G
E
K
T
F
E
Q
A
A
G
F
L
R
V
M
N
G
D
N
P
----
L
D
A
S
A
V
H
P
E
T
Y
P
----
L
V
Q
R
-
I
A
A
D
T
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R
DIRSL
I
-
G
D
S
A
F
L
K
---
R
L
D
P
K
K
F
T
D
E
T
----
F
G
L
P
T
V
T
D
I
L
K
E
L
D
K
P
G
R
D
P
R
P
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F
K
T
A
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F
Q
E
G
V
E
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L
K
D
L
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P
G
M
V
L
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V
V
T
N
V
T
N
F
G
A
F
V
D
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--
V
-
H
Q
D
G
L
V
H
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A
L
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F
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V
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K
V
K
V
M
E
V
D
I
P
R
N
--
R
V
G
L
S
M
-------
1
PsiBlast_PDB
78.81
43%
-90
- C4 -
2OCE
-
?
A:
[23-723]
----------------------------------------------------------------------------------
Q
Q
V
A
A
A
V
A
L
L
-
D
E
G
S
T
V
P
F
I
A
R
Y
R
K
E
V
T
G
S
-------
L
D
D
T
Q
L
R
M
L
E
E
R
L
R
Y
L
R
E
L
E
E
R
R
G
A
I
L
A
S
I
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Q
G
K
L
T
P
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L
A
R
D
I
K
L
A
D
T
K
T
R
L
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D
L
Y
L
P
Y
K
Q
K
R
R
T
K
G
Q
I
A
L
E
A
G
L
G
A
L
A
D
A
L
F
-------------------------
D
D
P
T
L
V
P
E
S
E
A
A
R
F
V
D
A
E
K
G
F
A
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V
K
A
V
L
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G
A
K
Y
I
L
M
E
R
F
A
E
D
A
T
L
----
L
D
K
L
R
V
F
M
K
N
E
A
T
L
---
T
A
R
V
V
P
G
K
E
---
Q
E
G
A
K
F
S
D
Y
F
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H
D
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P
L
K
S
A
P
--
S
H
R
A
L
A
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G
R
N
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L
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A
S
L
K
V
G
E
E
-
A
------
P
G
T
L
H
P
C
E
------
V
M
I
A
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R
F
G
-
L
S
-----
N
----
Q
G
-------
R
A
A
D
K
W
L
A
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V
V
R
W
T
W
K
V
K
L
Y
T
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L
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L
F
G
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L
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A
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L
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L
L
L
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P
A
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P
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A
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L
G
L
D
P
G
L
R
T
G
-----------
V
K
V
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V
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L
L
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A
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L
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K
K
Y
P
G
M
-
K
---------
L
T
K
I
M
V
S
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A
G
A
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V
Y
S
A
S
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L
A
A
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L
R
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A
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A
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R
L
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P
L
A
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L
V
K
I
---
E
P
K
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I
G
V
G
Q
Y
Q
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L
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L
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V
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N
A
V
G
V
D
V
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T
A
-----
S
A
A
L
L
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L
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A
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-
A
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F
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M
N
G
D
N
P
----
L
D
A
S
A
V
H
P
E
T
Y
P
----
L
V
Q
R
-
I
A
A
D
T
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R
DIRSL
I
-
G
D
S
A
F
L
K
---
R
L
D
P
K
K
F
T
D
E
T
----
F
G
L
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T
V
T
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I
L
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L
D
K
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R
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A
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V
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L
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L
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L
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V
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F
G
A
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--
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-
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V
K
V
M
E
V
D
I
P
R
N
--
R
V
G
L
S
M
-------
50
Fugue
76.75
41%
-84
- C4 -
2OCE
-
?
A:
[2-730]
-----------------------------------------------
D
S
I
N
T
R
I
A
E
E
L
S
A
L
P
SG
R
------
V
Q
--------
P
Q
Q
V
A
A
A
V
A
L
L
-
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T
V
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R
K
E
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T
G
S
-------
L
D
D
T
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L
R
M
L
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R
L
R
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L
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R
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A
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L
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K
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Q
I
A
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A
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L
G
A
L
A
D
A
L
F
D
D
----------------------
P
T
L
V
-
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--
S
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A
A
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F
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A
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G
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A
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Y
I
L
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R
F
A
E
D
A
T
L
----
L
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L
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N
E
A
T
L
---
T
A
--
R
V
V
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-
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--
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A
L
A
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R
G
R
N
E
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L
----
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A
S
L
K
-
V
------
G
E
E
-
A
P
G
T
------
L
H
--
P
C
E
V
-
M
I
-----
A
----
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R
F
GLSNQG
R
A
A
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W
L
A
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V
V
R
W
T
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L
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L
D
P
G
L
R
T
G
-----------
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K
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D
K
L
A
G
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L
I
K
K
Y
P
-
G
M
K
---------
L
T
K
I
M
V
S
E
A
G
A
S
V
Y
S
A
S
E
L
A
A
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E
F
P
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L
D
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S
L
R
G
A
V
S
I
A
R
R
L
Q
D
P
L
A
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L
V
K
I
---
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P
K
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I
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V
G
Q
Y
Q
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L
K
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C
V
N
A
V
G
V
D
V
N
T
A
-----
S
A
A
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L
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L
N
S
T
L
A
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N
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V
A
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-
A
F
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L
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K
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F
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Q
A
A
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F
L
R
V
M
N
G
D
N
P
----
L
D
A
S
A
V
H
P
E
T
Y
P
L
V
Q
R
I
A
A
D
-
T
E
R
D
I
R
S
-----
L
-
I
G
D
--
S
A
---
F
L
K
R
L
D
P
K
K
F
T
D
E
-
T
F
G
L
P
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V
T
D
I
L
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L
D
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D
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R
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A
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L
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V
T
N
F
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A
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--
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-
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Q
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D
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V
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E
V
D
I
P
R
N
--
R
V
G
L
S
M
R
M
SDTPG
3
PsiBlast_PDB
76.39
43%
-90
- C- -
3BZK
-
?
A:
[23-723]
----------------------------------------------------------------------------------
Q
Q
V
A
A
A
V
A
L
L
-
D
E
G
S
T
V
P
F
I
A
R
Y
R
K
E
V
T
G
S
-------
L
D
D
T
Q
L
R
M
L
E
E
R
L
R
Y
L
R
E
L
E
E
R
R
G
A
I
L
A
S
I
E
E
Q
G
K
L
T
P
E
L
A
R
D
I
K
L
A
D
T
K
T
R
L
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D
L
Y
L
P
Y
K
Q
K
R
R
T
K
G
Q
I
A
L
E
A
G
L
G
A
L
A
D
A
L
F
-------------------------
D
D
P
T
L
V
P
E
S
E
A
A
R
F
V
D
A
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K
G
F
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L
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L
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F
M
K
N
E
A
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L
--
T
A
---
R
V
--
V
P
G
K
E
---
Q
E
G
A
K
F
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D
Y
F
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H
D
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P
L
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A
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--
S
H
R
A
L
A
I
F
R
G
R
N
E
G
V
L
S
A
S
L
K
V
G
---
A
------
P
G
T
L
H
P
C
E
------
V
M
I
A
E
R
F
G
-
L
S
-----
N
----
Q
G
-------
R
A
A
D
K
W
L
A
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V
V
R
W
T
W
K
V
K
L
Y
T
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L
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L
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A
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A
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L
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L
L
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A
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P
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A
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L
G
L
D
P
G
L
R
T
G
-----------
V
K
V
A
V
V
D
A
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L
L
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A
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A
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D
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L
A
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L
I
K
K
Y
P
G
M
-
K
---------
L
T
K
I
M
V
S
E
A
G
A
S
V
Y
S
A
S
E
L
A
A
K
E
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P
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L
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L
R
G
A
V
S
I
A
R
R
L
Q
D
P
L
A
E
L
V
K
I
---
E
P
K
S
I
G
V
G
Q
Y
Q
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D
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L
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L
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L
D
A
V
V
E
D
C
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N
A
V
G
V
D
V
N
T
A
-----
S
A
A
L
L
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L
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L
A
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V
A
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-
A
F
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K
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L
G
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K
T
F
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Q
A
A
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F
L
R
V
M
N
G
D
N
P
----
L
D
A
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A
V
H
P
E
T
Y
P
----
L
V
Q
R
-
I
A
A
D
T
E
R
DIRSL
I
-
G
D
S
A
F
L
K
---
R
L
D
P
K
K
F
T
D
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T
----
F
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L
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I
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L
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A
E
F
Q
E
G
V
E
S
L
K
D
L
K
P
G
M
V
L
E
G
V
V
T
N
V
T
N
F
G
A
F
V
D
I
G
--
V
-
H
Q
D
G
L
V
H
I
S
A
L
S
E
K
F
V
K
D
P
Y
E
V
V
K
A
G
D
I
V
K
V
K
V
M
E
V
D
I
P
R
N
--
R
V
G
L
S
M
-------
52
Fugue
50.00
16%
-75
- C4 -
3PSF
-
SPT6_YEAST
A:
[298-1248]
D
I
Y
D
L
E
D
L
K
K
N
LMT
E
G
D
M
K
I
R
K
TDIP
E
R
Y
Q
E
L
R
A
GITDYGNMS
S
E
D
Q
E
L
E
R
N
W
I
A
E
K
I
S
V
D
K
--
N
------
F
D
ANYDL
T
E
F
K
E
A
I
G
N
A
I
K
F
I
T
K
E
N
L
E
V
P
F
I
Y
A
Y
R
R
N
Y
I
S
S
REKDGFL
L
T
E
D
D
L
W
D
I
V
S
L
D
I
E
F
H
S
L
V
N
K
K
D
Y
V
Q
R
F
Y
A
E
L
H
I
D
D
P
I
V
T
E
Y
F
K
N
Q
N
S
L
Q
D
I
Y
D
-
Y
L
E
F
K
Y
A
N
E
I
N
E
M
S
Y
E
K
F
K
A
S
P
L
Y
Q
A
V
S
D
I
GIS
A
E
D
V
G
E
N
I
S
S
QHQIHPPVD
H
P
S
S
K
P
V
--
E
V
I
E
S
I
L
N
A
N
S
G
D
L
Q
T
K
L
A
I
D
T
V
Q
K
Y
Y
S
L
E
L
S
K
N
T
K
I
----
R
E
K
V
R
S
D
F
S
K
Y
Y
L
A
D
V
V
L
T
--
A
K
G
K
K
E
I
Q
K
G
S
L
Y
E
D
I
K
Y
A
I
N
R
T
P
M
H
F
R
R
D
P
D
V
F
L
K
M
V
E
A
E
S
L
N
L
L
----
S
V
K
L
H
M
S
------
S
Q
A
-
Q
Y
I
E
------
H
L
--
F
Q
I
A
-
L
E
TTNTS
D
----
I
A
-------
I
E
W
N
N
F
R
K
L
A
F
N
Q
A
M
D
K
I
F
-
Q
D
I
S
Q
E
V
K
D
N
L
T
K
N
C
Q
K
L
V
A
K
T
V
R
H
K
F
M
T
K
L
D
Q
A
P
F
I
P
N
V
R
D
P
K
I
P
K
I
L
S
L
T
CGQGRFGA
D
A
I
I
A
V
Y
V
N
R
K
G
D
F
I
R
D
Y
K
I
V
D
N
P
F
D
K
T
N
P
E
K
F
E
D
T
L
D
N
I
I
Q
S
C
Q
P
N
A
I
G
I
N
--
G
P
N
P
K
T
Q
K
F
Y
K
R
L
Q
E
V
L
H
-
K
-
K
QIVDSRGHT
I
P
I
I
Y
V
E
D
E
V
A
I
R
Y
Q
N
S
E
R
A
A
Q
E
F
P
N
K
P
P
L
V
K
Y
C
I
A
L
A
R
Y
M
H
S
P
L
L
E
Y
A
N
L
T
S
E
E
V
R
S
L
S
I
H
P
H
Q
N
L
L
S
S
E
Q
L
S
W
A
L
E
T
A
F
V
D
I
V
N
L
V
S
V
E
V
N
K
A
T
D
N
NY
Y
A
S
A
L
K
Y
I
S
G
F
G
K
R
K
A
I
D
F
L
Q
S
L
Q
R
L
N
E
P
L
L
A
R
Q
Q
L
I
T
H
N
I
L
H
K
T
I
F
M
N
S
A
G
F
L
Y
I
S
W
N
E
D
L
EHDQ
L
D
S
T
R
I
H
P
E
D
Y
H
L
A
T
K
V
A
A
D
A
L
E
Y
D
P
D
T
-----
I
-
A
E
K
E
E
Q
G
TMS
E
F
I
E
L
L
R
E
D
P
D
R
R
A
K
L
E
S
L
N
L
E
S
Y
A
E
E
L
E
K
N
T
G
L
R
K
L
N
N
L
N
T
I
V
L
E
L
L
D
G
F
E
E
L
R
N
D
F
H
P
L
--------------------------
Q
G
D
E
I
F
Q
S
L
T
G
E
S
S
K
D
P
S
I
W
D
L
K
Q
E
L
E
D
A
E
E
E
R
K
L
--
M
M
A
E
A
R
A
K
-----
8
PsiBlast_PDB
43.03
43%
-170
- C4 -
4NNK
-
RS1_MYCTU
A:
[294-362]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
Q
I
V
P
G
K
V
T
K
L
V
P
F
G
A
F
V
R
V
E
--
E
-
G
I
E
G
L
V
H
I
S
E
L
A
E
R
H
V
E
V
P
D
Q
V
V
A
V
G
D
D
A
M
V
K
V
I
D
I
D
L
E
R
R
--
R
I
S
L
S
L
-------
7
PsiBlast_PDB
42.23
43%
-170
- C4 -
4NNG
-
RS1_MYCTU
A:
[294-362]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
Q
I
V
A
G
K
V
T
K
L
V
P
F
G
A
F
V
R
V
E
--
E
-
G
I
E
G
L
V
H
I
S
E
L
A
E
R
H
V
E
V
P
D
Q
V
V
A
V
G
D
D
A
M
V
K
V
I
D
I
D
L
E
R
R
--
R
I
S
L
S
L
-------
6
PsiBlast_PDB
41.88
44%
-170
- C4 -
4NNH
-
RS1_MYCS2
A:
[294-362]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
Q
I
V
P
G
K
V
T
K
L
V
P
F
G
A
F
V
R
V
E
--
E
-
G
I
E
G
L
V
H
I
S
E
L
S
E
R
---
V
P
D
Q
V
V
Q
V
G
D
D
A
M
V
K
V
I
D
I
D
L
E
R
R
--
R
I
S
L
S
L
-------
29
HHSearch
40.63
39%
-160
- C4 -
4NNG
-
RS1_MYCTU
A:
[288-363]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
T
H
A
I
G
Q
I
V
A
G
K
V
T
K
L
V
P
F
G
A
F
V
R
V
E
--
E
-
G
I
E
G
L
V
H
I
S
E
L
A
E
R
H
V
E
V
P
D
Q
V
V
A
V
G
D
D
A
M
V
K
V
I
D
I
D
L
E
R
R
--
R
I
S
L
S
L
K
------
36
HHSearch
40.51
24%
-181
- C4 -
2A19
-
IF2A_YEAST
A:
[14-87]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
I
D
D
I
V
M
V
N
V
Q
Q
I
A
E
M
G
A
Y
V
K
L
L
EY
D
-
N
I
E
G
M
I
L
L
S
--------
S
I
Q
K
L
I
R
V
G
K
N
D
V
A
V
V
L
R
V
D
K
E
K
G
--
Y
I
D
L
S
K
R
------
9
PsiBlast_PDB
40.38
43%
-154
- C4 -
4NNI
2
RS1_MYCTU
A:
[17-85]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
Q
I
V
P
G
K
V
T
K
L
V
P
F
G
A
F
V
R
V
E
--
E
-
G
I
E
G
L
V
H
I
S
E
L
A
E
R
H
V
E
V
P
D
Q
V
V
A
V
G
D
D
A
M
V
K
V
I
D
I
D
L
E
R
R
--
R
I
S
L
S
L
-------
15
PsiBlast_PDB
39.79
29%
-168
- C4 -
3AEV
-
IF2A_PYRHO
A:
[11-82]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
G
E
F
V
V
A
T
V
K
R
I
H
N
Y
G
A
F
L
E
L
D
EY
P
-
G
K
E
A
F
M
H
I
S
E
V
A
S
T
W
V
R
N
I
R
D
Y
L
K
E
G
Q
K
V
V
A
K
V
I
R
V
D
P
R
K
G
--
H
I
D
L
S
L
-------
11
PsiBlast_PDB
39.35
43%
-177
- C4 -
5IE8
-
?
A:
[294-362]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
Q
I
V
P
G
K
V
T
K
L
V
P
F
G
A
F
V
R
V
E
--
E
-
G
I
E
G
L
V
H
I
S
E
L
A
E
R
H
V
E
V
P
D
Q
V
V
A
V
G
D
D
A
M
V
K
V
I
D
I
D
L
E
R
R
--
R
I
S
L
S
L
-------
17
PsiBlast_PDB
39.22
40%
-163
- C4 -
1GO3
-
RPOE1_METJA
E:
[85-127]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
E
G
E
V
V
D
V
V
E
F
G
S
F
V
R
L
G
----
P
L
D
G
L
I
H
V
S
Q
I
M
D
D
Y
V
S
Y
--------------------------------------
21
PsiBlast_CBE
38.50
43%
-154
- C4 -
4NNI
2
B:
[17-85]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
Q
I
V
P
G
K
V
T
K
L
V
P
F
G
A
F
V
R
V
E
--
E
-
G
I
E
G
L
V
H
I
S
E
L
A
E
R
H
V
E
V
P
D
Q
V
V
A
V
G
D
D
A
M
V
K
V
I
D
I
D
L
E
R
R
--
R
I
S
L
S
L
-------
49
HHSearch
38.29
38%
-139
* C4 *
2CQO
-
NO40_HUMAN
A:
[13-88]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
A
L
Y
T
I
F
Q
G
E
V
A
M
V
T
D
Y
G
A
F
I
K
I
P
--
G
C
R
K
Q
G
L
V
H
R
T
H
M
S
S
C
R
V
D
K
P
S
E
I
V
D
V
G
D
K
V
W
V
K
L
I
G
R
E
M
K
N
D
R
I
K
V
S
L
S
M
K
------
27
HHSearch
38.25
41%
-164
- C4 -
2K4K
-
GS13_BACSU
A:
[4-77]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
F
E
V
G
S
V
Y
T
G
K
V
T
G
L
Q
A
Y
G
A
F
V
A
L
D
--
E
-
E
T
Q
G
L
V
H
I
S
E
V
T
H
G
F
V
K
D
I
N
E
H
L
S
V
G
D
E
V
Q
V
K
V
L
A
V
D
E
E
K
G
--
K
I
S
L
S
I
R
------
46
HHSearch
38.14
24%
-157
- C4 -
1KL9
1
IF2A_HUMAN
A:
[12-87]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
P
E
V
E
D
V
V
M
V
N
V
R
S
I
A
E
M
G
A
Y
V
S
L
L
EY
N
-
N
I
E
G
M
I
L
L
S
E
L
------------
R
I
G
R
N
E
C
V
V
V
I
R
V
D
K
E
K
G
--
Y
I
D
L
S
K
R
------