@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu04940: (2016-06-08 )
MRLKTPMKAIHKNLLLTRTGDVWAYYRIKSNSIPMQNKEKVESYKKKWQHLFEEITSYEDFHLMMYPSEYELEKRFKDLETDIAADAMDVARYYNEETVRLLEQRLGRLTKYDFILGVKLKSSLVNISVELKDNILSFFNTATDTVVKMLGWEQNVSTSFFEKYEEVEETLANIMASVRGERLSETEMTYINRYHFVRGLKHQTNEESEIKDVRSITNTIIDPTDPSVLHLHSDQDEGYSAFVVIDEFLHNMSESDLFYEAQSLPFPVEVQMKIQTESKSITKPALNLKRQQLKEEQKEQQSTGDRSDVSTVTSATMIRHLQDEIKKEDVHVMNWLSVIVVHGKTKKECVGKATIVKRHLKGAGITCRLPVADQLNLFYKMLPGEKLDITDKNWIQKTTQDGVAESLFAVNSDIGSKIGFFLGWVDRFQEHTDLESAIMSSRDFVLFHPFLANQQLKGSKTRSPHCLITGDTGNGKSYLAKLIFNYISMLNIKSLYIDPKKEMRKWIQRVLNDEYIRENFPLYIAHLEKYNYITLDHENTHNWGALDPISFLPPMKAKELVQVIFEQVYDFKGKDDINTAFLRATSEVIDAKQKGEQVGSLDIIRKMQSHPEEAVQKAGDYLNEVVSDSILKLCIHDGSNPALSLEKRITILEVENMDLPDHAERLENYTISQLKSSAVMFALGKFCELFGMNQDEQTVEFIDEAWIFTTSQQGKKVERQMRRIGRSYNNAEYFISQSTKDALKEEDSGNFGVAFAFDEPNEREEVLKWMNMEVTKDNKKMMESMFQGQCLFKDYYGRTSKISIECLFEEWQGALKTVEKKAVAYAEEKYL
Atome Classification :
(20 SA)
--------------------------------------.........10........20........30........40.-----.......50.......---.60........70....---..-----..80........90........100.......110.......120.......130.......140.......150......----.160..------.....--170.......180........190-.........200.......210.......--220.......230.----......240-.....--..250.......260......--.270.......280......---.290------------.......----------------..300.......310.......320.......330.......340...-----------....350......-.360-..-....---.370.....---------..---380-.......390.-----.......400.---.....-.410......-.420.......430------.........440......-----.-450...--------.--...460....---...470....-...480...-------.-----..-..490--.--......-..---500..--------.....510....---------...520----....-...530........540.--......550..---------------...-------..560...---....570.......580.-.-.....590--.-----------......600.......610..---......620.......630.......640....-----------------...650.......660.......670.......680--.......690.......700....-.------------.-.710-........720......--.730.......-----740...-------....750....-------...760.-.......770........780...------------....790.......800.......810-.-......820.......830-----------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------------------MRLKT
P
M
K
A
I
H
KN
L
L
L
TRTG
D
V
W
A
Y
Y
R
I
KSNSIPMQ
N
K
E
K
V
E
-----
S
Y
K
K
K
W
Q
H
L
F
E
E
I
TSY---E
D
F
H
L
M
MYP
S
E
Y
E
L
E
K
R
---
F
K
-----
D
L
E
T
D
I
A
A
D
A
M
D
V
A
R
Y
Y
N
E
E
T
V
R
L
L
E
Q
R
L
G
RLT
K
Y
D
F
I
L
G
V
K
L
KS
S
L
V
N
I
S
V
E
L
K
D
N
I
L
S
F
F
N
T
A
T
D
T
V
V
K
M
LGWEQNV
S
T
----
S
F
F
E
K
Y
------
E
E
V
E
E
--
T
L
A
N
I
M
A
S
V
RG-ERLSE
T
E
M
T
Y
---
I
N
R
Y
H
F
V
R
GLKHQTN
E
E
S
E
I
K
D
V
R
S
I
T
N
T--IIDPTDP
S
V
L
H
L
HS----DQDEG
Y
S
A
F
-
V
V
I
D
E
--
F
L
H
NMSESD
L
F
Y
EAQSLPF
P
V
--
E
V
Q
M
K
I
QTESKSITK
P
A
L
N
L
---
K
R
--------------
Q
Q
L
K
E
E
Q
----------------
K
E
Q
QSTGDRS
D
V
S
T
V
T
S
A
T
M
I
R
H
L
Q
D
E
I
K
KED
V
H
V
M
N
W
L
S
V
I
V
VHGK
T
-----------
K
K
E
CV
G
K
A
T
I
V
K
R
-
H
LKG-AG-
I
T
C
R---LP
V
A
D
Q
L
N
L
---------
F
Y
---
K
ML-PGEKLDIT
D
-
K
-----
N
W
I
Q
K
T
T
Q
D
G
V
---
A
E
S
L
F
-
A
VNS
D
I
G
S
K
I
-
G
F
F
L
G
W
V
D
R
F
Q
E
--------H
T
D
L
E
S
A
I
MSSR
D
F
V
L
F
H
-----
P
-
F
LANQQ--------L--KGSKTRS
P
H
C
---
L
I
TGDTGN
G
K
-
S
Y
L
A
K
-
L
I
F
-------
N
-----
Y
I
-
S
M
L
----
N
--
I
K
S
L
YI-D
P
---
K
K
E
M
R
--------
K
W
I
Q
R
V
LN
D
E
Y
I
---------RENF
P
L
----
Y
I
A
H-LEKY-
N
Y
I
T
L
DHENTHNW--GAL
D
P
I
SFLPP---------------M
K
A
-------
K
E
L
V
Q
V
I
F
---
E
Q
V
YDFKGKDD
I
N
T
A
F
L
R
-
A
-
T
S
E
V
I
D
A
K
--
Q
-----------KGEQVG
S
L
D
I
I
R
K
M
Q
SH-
P
E
E
---
A
V
Q
K
A
G
D
Y
L
N
E
V
V
S
D
S
I
L
K
L
C
IHDGSNP
A
L
S
L
E
-----------------
K
R
I
T
I
L
E
VENMDL
P
D
H
A
E
R
L
E
N
Y
T
I
S
Q
L
K
S
S
A
V
M
F
A
--
L
G
K
F
C
E
L
FGMNQ
D
E
Q
T
V
E
F
I
D
EA
W
-
I
------------F-TTS--QQ
G
K
K
V
E
R
Q
M
R
R
IGRSY--NN
A
E
Y
F
ISQS
T
-----
K
D
A
LKE-------EDSGNF
G
V
A
F
A-------FDEPN-
E
-
R
E
E
V
L
K
W
M-N
M
E
VTKD
N
K
K
M
M
E
S
M
------------FQG
Q
C
L
F
K
D
YYGRTS
K
I
S
I
E
C
L
F
E
E
W
Q
-
G
-
A
L
K
T
V
E
K
K
A
V
A
Y
A
EEKYL------------------------------------------------------------------------------------------------------------
46
Fugue
66.89
16%
-28
- C3 -
5GAN
-
PRP6_YEAST
J:
[155-898]
--------------------------------------
G
N
V
D
L
N
K
L
T
E
E
R
E
K
L
L
Q
S
Q
I
D
E
N
L
A
Q
L
T
K
N
A
S
N
P
I
Q
V
N
K
P
N
A
ATDAL
S
Y
L
K
D
L
E
N
--
D
R
V
N
S
L
---
S
D
A
T
L
E
D
L
Q
K
M
R
T
I
L
K
S
---
Y
R
KADPT
N
P
Q
G
W
I
A
S
A
R
L
E
E
K
A
R
K
F
S
V
A
K
K
I
I
E
N
G
C
Q
E
C
P
R
---------
S
S
D
I
W
L
E
N
I
R
L
H
E
S
D
V
H
Y
C
K
T
L
V
A
T
A
I
N
F
----
N
P
T
S
P
----
L
L
W
F
K
A
------
I
D
L
E
S
--
T
T
V
N
K
Y
R
V
V
R
K
-
A
L
Q
E
I
P
R
-------
D
E
G
L
W
K
L
A
V
S
F
E
A
D
K
A
Q
V
I
K
M
L
E
K
A
T
Q
F
--
I
--
P
Q
S
M
D
L
L
T
A
Y
T
----
N
L
Q
S
Y
H
N
A
K
-
M
T
L
N
S
--
F
R
K
I
L
P
Q
E
P
----------
E
I
--
W
I
I
S
T
L
L
E
E
R
N
N
--
P
K
L
V
S
L
---
L
K
--------------
E
G
L
L
E
L
S
----------------
K
------------
N
G
Y
K
A
T
L
S
A
W
L
K
R
A
E
A
L
N
D
------------
A
P
N
S
-----------
N
L
T
C
Q
A
I
V
Y
A
I
L
E
-
W
L
R
E
-
S
G
---
E
Y
---
E
S
E
L
N
N
V
D
Q
---------
I
L
---
E
K
M
-
P
H
S
K
V
Q
I
A
V
L
K
-----
K
L
I
Q
W
D
P
C
D
T
V
---
L
W
S
R
L
-
K
M
A
T
E
S
Y
E
E
L
-
L
A
F
F
Q
--
E
L
L
F
Q
--------
T
S
D
D
I
R
A
N
M
R
E
K
S
P
G
L
L
M
-----
M
-
Y
V
S
E
Y
W
--------
K
--
A
Q
K
G
D
T
R
Q
T
L
---
V
L
I
D
Q
I
I
D
F
A
-
P
H
N
L
D
-
L
R
F
-------
F
-----
K
I
-
K
L
L
----
G
---
R
S
L
Q
L
-
D
E
---
L
R
D
F
F
--------
Q
Q
T
F
S
S
L
E
D
F
K
I
---------
S
G
T
E
R
L
----
Y
Y
K
Y
-
V
N
F
L
-
R
Y
Q
D
L
N
E
E
A
I
K
F
L
--
N
E
R
C
L
K
S
F
P
I
C
---------------
H
K
F
-------
F
L
Q
L
G
Q
I
Y
---
H
S
M
---
G
N
I
E
M
S
R
E
T
Y
L
S
-
G
-
T
R
L
V
P
N
C
P
--
L
-----------
L
W
V
S
L
S
K
I
D
E
I
-------------------
D
L
K
N
P
V
R
A
R
S
I
L
D
R
G
L
L
K
N
P
D
D
V
L
F
Y
I
-----------------
A
K
I
Q
-
M
E
I
R
L
G
N
L
-
D
Q
A
E
L
L
V
T
Q
A
L
Q
K
F
P
S
N
A
L
L
W
V
----
E
Q
I
K
L
F
K
H
G
N
K
S
S
L
K
K
T
I
F
Q
D
A
-
L
------------
R
-
R
T
---
Q
N
D
H
R
V
L
L
E
I
G
V
S
F
Y
A
E
--
A
Q
Y
E
T
S
L
K
W
L
E
-----
R
A
L
K
K
C
-------
S
R
Y
G
D
T
W
V
W
L
F
-------
R
T
Y
A
R
-
L
-
G
K
D
----------
T
V
D
L
Y
N
M
F
D
Q
C
-------------------
E
P
T
Y
G
-----------
P
E
W
I
-
A
-
A
S
K
N
C
T
P
R
E
I
L
L
R
L
M
N
D
-------------------------------------------------------------------------------------------------------------
21
HHSearch
64.16
18%
-95
- C2 -
4AG6
3
?
A:
[3-386]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
G
I
N
D
G
S
-
G
I
V
L
G
K
D
R
D
----------------------
G
G
L
V
L
V
D
-----
I
-
W
K
R
G
G
---------------
D
R
T
N
S
N
W
---
T
I
L
A
K
P
G
A
G
K
-
S
F
T
A
K
-
M
L
L
-------
L
-----
R
E
-
Y
M
Q
----
G
--
S
R
V
I
I
I
-
D
P
---
E
R
E
Y
K
--------
E
M
C
R
K
L
-------------------------------
G
-
G
-
V
W
I
N
C
T
G
----
G
E
--
G
K
I
N
P
L
Q
V
R
L
R
---------------
P
--QS
P
L
A
L
H
I
Q
T
L
R
T
F
F
---
S
L
Y
L
R
-
D
L
T
D
T
E
K
A
A
L
E
D
-
A
-
L
V
E
V
Y
K
E
A
--
G
ITWDTDPRGVP
N
D
K
W
P
T
V
K
E
L
Y
E
Y
C
V
K
K
-
A
E
E
NPE
T
Y
G
R
L
S
V
L
L
K
R
A
A
E
G
A
D
-
S
Y
L
W
A
G
P
-
T
-
A
V
E
A
D
-----------------
S
D
F
I
V
F
D
V
H
D
L
Q
N
A
E
----------
D
Q
V
K
R
A
Q
Y
F
N
V
--
L
S
F
A
W
N
I
L
E
R
D
R
R
E
R
T
V
L
V
V
D
E
A
W
-
M
------------
L
-
V
D
P
QT
P
Q
A
I
A
F
L
R
D
T
S
K
R
I
R
K
Y
--
N
G
S
L
I
V
I
S
Q
N
V
-----
I
D
F
L
A
P
EV
Q
R
Y
G
Q
A
L
L
D
N
P
T
Y
K
L
L
-------
L
A
Q
G
E
K
D
-
L
E
A
I
T
T
L
M
-
N
L
S
E
A
E
--
H
D
L
L
V
N
A
------------
K
R
G
E
G
L
F
V
A
G
T
Q
-
R
I
H
I
K
I
E
-
A
A
P
Y
E
M
-
Q
-
Y
-----------------------------------------------------------------------------------------------------------------------------
47
Fugue
58.79
15%
-41
- C3 -
2PO4
-
RPOLV_BPN4
A:
[11-1104]
G
I
D
A
V
Y
PSLVGTADSKAEGIKN
Y
F
K
L
S
F
TLPEEQKSRT
V
G
S
E
A
P
L
K
D
V
A
Q
A
L
---
S
S
R
A
R
Y
E
L
F
T
E
K
E
T
A
N
P
A
F
N
G
E
V
I
K
-----
R
Y
K
E
L
M
E
H
G
-
E
G
I
A
D
I
---
L
R
S
R
L
A
K
F
L
N
T
K
D
V
G
K
R
---
F
A
-----
Q
--------
G
T
E
A
N
R
W
V
G
G
K
L
L
N
I
V
E
Q
D
G
D
T
F
K
Y
N
E
Q
L
L
Q
T
A
V
---
L
A
G
L
Q
W
R
L
T
A
T
S
N
T
A
I
K
D
A
K
D
V
A
A
I
T
G
I
D
Q
A
L
L
P
E
----
G
L
V
E
Q
F
D
T
G
MT
L
T
E
A
V
S
--
S
L
A
Q
K
I
E
S
Y
W
G
L
S
R
N
P
N
A
P
L
G
Y
T
K
G
I
P
T
A
M
A
A
E
I
L
A
A
F
V
E
S
T
D
V
V
E
N
I
V
D
M
S
E
----
I
D
P
D
N
K
K
T
I
G
L
Y
T
I
TEL
D
S
F
D
P
I
N
S
F
P
T
A
I
E
E
--
A
V
L
V
N
P
T
E
K
M
F
F
G
D
D
I
P
P
V
A
N
--
T
Q
L
R
N
P
A
V
R
N
T
P
E
Q
K
A
A
L
K
A
---
E
Q
A
T
E
F
Y
V
H
T
P
M
V
Q
F
Y
E
T
L
G
K
D
R
I
L
E
L
M
G
AGTLNKELLN
D
N
H
A
K
S
L
E
G
K
N
R
S
V
E
D
S
Y
N
Q
L
F
S
V
I
E
Q
V
R
A
Q
S
----
E
D
I
S
T
V
P
I
H
Y
A
Y
-----------
N
M
T
R
V
G
R
M
Q
M
L
G
K
-
Y
N
P
Q
-
S
A
-
K
L
V
R
E
A
I
L
P
T
K
A
T
L
D
L
SNQNN
E
D
F
S
A
F
---
Q
L
G
-
L
A
Q
A
L
D
I
K
----------
V
H
T
M
T
R
E
V
M
---
S
D
E
L
T
-
K
L
L
E
G
---
N
L
-
K
P
A
I
D
M
M
V
E
F
N
T
TGSLPEN
A
V
D
V
L
N
T
A
L
G
D
R
K
S
F
V
A
L
M
-----
A
-
L
M
E
Y
S
R
--------
Y
--
L
V
A
E
D
K
S
A
F
V
T
P
L
Y
V
E
A
D
G
V
T
N
G
-
P
I
N
A
M
-
M
L
M
TGGLFT
P
D
-----
W
I
-
R
N
I
----
A
--
K
G
G
L
F
I
G
S
P
---
N
K
T
M
N
--------
E
H
R
S
T
A
D
N
N
D
L
Y
---------
Q
A
S
T
N
A
----
L
M
E
S
-
L
G
K
L
-
R
S
N
Y
A
S
N
M
P
I
Q
S
Q
I
D
S
L
L
S
L
M
D
L
F
L
P
DINLGENGALELKRG
I
A
K
-------
N
P
L
T
I
T
I
Y
GSG
A
R
G
I
A
G
K
L
V
S
S
V
T
D
A
I
Y
E
-
R
-
M
S
D
V
L
K
A
R
--
A
-----------
K
D
P
N
I
S
A
A
M
A
M
F
G
K
Q
A
A
-
S
E
A
---
H
A
E
E
L
L
A
R
F
L
K
D
M
E
T
L
T
S
T
V
P
V
K
R
K
G
V
L
E
L
Q
S
T
GTGAKGKINPK
T
Y
T
I
K
G
E
Q
L
K
A
L
Q
E
N
M
L
H
F
F
--
V
E
P
L
R
N
G
I
T
Q
T
V
G
E
S
L
V
Y
S
T
E
Q
L
Q
K
A
T
Q
I
Q
S
V
V
L
E
D
M
F
K
Q
R
V
Q
E
K
L
-
A
E
K
A
K
DPTWKKGD
F
-
L
T
Q
--
K
E
L
N
D
I
Q
A
S
L
N
N
L
A
P
M
I
ET
G
S
Q
T
F
Y
I
A
G
S
E
N
AEVA
N
Q
V
L
A
T
-------
N
L
D
D
R
M
R
V
P
M
S
-------
I
Y
A
P
A
-
Q
A
G
V
A
G
I
P
F
M
-
T
I
G
T
G
-
D
G
M
M
M
Q
T
L
S
T
MKGAPKNTLKI
F
D
G
M
N
I
G
L
N
D
I
T
D
A
S
R
K
A
N
E
A
V
Y
T
S
W
Q
-
G
N
P
I
K
N
V
Y
E
S
Y
A
K
F
M
K
N
V
D
F
SKLS
P
E
A
L
E
A
I
G
K
S
A
L
EYDQRENAT
V
D
D
I
A
N
A
A
S
L
I
E
R
N
L
R
N
I
A
L
G
V
D
I
R
H
K
V
L
D
K
V
N
L
S
I
DQMAAVG
A
P
Y
Q
NNGKIDLSNMT
P
E
Q
Q
A
D
E
L
N
K
L
F
R
E
E
L
E
A
R
K
Q
K
V
A
K
44
Fugue
54.72
18%
-82
- C2 -
4AG6
3
?
A:
[3-385]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
G
I
N
D
G
S
G
I
V
L
G
K
DRDG
G
L
-
V
L
V
D
I
W
--------
K
--
R
G
G
D
R
T
N
S
N
W
---
T
I
L
A
K
P
G
A
G
K
-
S
F
T
A
K
M
L
L
L
-------
R
-----
E
Y
M
Q
------
G
--
S
R
V
I
I
I
-
D
P
---
E
R
E
Y
K
E
M
C
R
K
L
GG
V
W
I
N
C
T
G
G
E
G
K
I
NPLQ
V
R
L
R
P
Q
S
P
L
A
L
----
H
I
Q
T
-
L
R
T
F
-
F
S
L
Y
L
R
D
-----------------
L
T
---------------
D
T
E
-------
K
A
A
L
E
D
A
L
---
V
E
V
Y
K
E
A
G
I
T
W
------
D
-
T
-
D
P
R
G
V
P
N
D
--
K
-----------
W
P
T
V
K
E
L
Y
E
Y
C
V
K
K
A
E
E
-
N
P
E
---
T
Y
G
R
L
S
V
L
L
K
R
A
A
E
G
A
D
S
Y
L
W
---
A
G
P
T
A
V
E
A
D
-----------------
S
D
F
I
V
F
D
V
H
D
L
Q
N
A
E
----------
D
Q
V
K
R
A
Q
Y
F
N
V
--
L
S
F
A
W
N
I
L
E
R
D
R
R
E
R
T
V
L
V
V
D
E
A
W
M
L
------------
V
D
P
Q
T
--
P
Q
A
I
A
F
L
R
D
T
S
K
R
I
R
K
Y
--
N
G
S
L
I
V
I
S
Q
N
V
-----
I
D
F
L
A
P
-------
E
V
Q
R
Y
G
Q
A
L
L
D
NPT
Y
K
L
L
L
A
Q
G
E
-
K
-
D
L
E
A
I
T
T
L
M
N
L
--
S
E
A
E
H
D
L
L
V
N
A
------------
K
R
G
E
G
L
F
V
A
---
G
T
Q
R
I
H
I
K
I
E
A
A
P
Y
E
M
Q
-
Y
-----------------------------------------------------------------------------------------------------------------------------
51
Fugue
42.98
15%
-51
- C3 -
2BVL
8
TOXB_PEPDI
A:
[1-543]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
S
L
V
N
-
R
K
Q
L
E
K
M
A
N
V
R
F
R
T
Q
E
D
E
Y
V
A
I
L
D
A
L
E
E
Y
H
N
MSEN
T
V
V
E
K
Y
------
L
K
L
K
D
I
N
S
L
T
D
I
C
I
D
T
Y
K
-
K
S
G
R
N
K
A
L
K
K
---
F
K
E
Y
L
V
T
E
V
L
E
L
K
N
N
N
L
T
P
V
E
K
N
L
H
F
V
W
I
GG
Q
I
N
D
T
A
I
N
Y
I
N
Q
W
K
----
D
V
N
S
D
Y
N
V
N
-
V
F
Y
D
S
NA
F
L
I
N
T
L
K
K
T
V
V
E
S
A
I
N
D
T
L
E
S
F
R
E
N
L
N
D
P
R
F
D
Y
N
K
F
F
R
K
R
M
E
I
I
Y
D
K
Q
--------------
K
N
F
I
N
Y
Y
----------------
K
A
Q
R
E
E
N
P
E
L
I
I
D
D
I
V
K
T
Y
L
S
N
E
Y
S
K
E
I
D
E
L
N
T
Y
I
E
E
S
L
N
K
I
T
Q
N
S
G
N
DVRNF
G
E
F
K
N
G
E
S
F
N
L
Y
E
Q
E
L
V
E
R
W
N
L
A
A
-
A
S
-
D
I
L
R
---
I
S
A
L
K
E
I
G
G
---------
M
Y
L
D
V
D
M
L
-
P
G
I
Q
P
D
L
F
E
-
S
IEKPS
S
V
T
V
D
F
W
E
M
T
K
---
L
E
A
I
M
-
K
Y
K
E
Y
I
P
E
Y
T
-
S
E
H
F
D
M
L
D
-
E
E
V
--------
Q
S
S
F
E
S
V
L
A
S
K
S
D
K
S
E
I
F
-----
S
-
S
L
G
D
M
E
A
S
PL
E
V
K
I
A
--
F
N
S
K
G
I
I
N
Q
G
---
L
I
S
V
K
D
S
Y
C
S
-
N
L
I
V
K
-
Q
I
E
-------
N
-----
R
Y
-
K
I
L
----
N
N
S
L
N
P
A
I
S
-
E
D
ND
F
N
T
T
T
N
--------
T
F
I
D
S
I
M
A
E
A
-----------
N
A
D
N
G
R
----
F
M
M
E
-
L
G
K
Y
-
L
R
V
------------
G
F
F
P
D
V
K
T
T
I
N
---------------
L
S
G
-------
P
E
A
Y
A
A
A
Y
---
Q
D
L
L
M
F
K
-
E
G
S
M
N
I
H
L
I
E
-
A
-
D
L
R
N
F
E
I
S
--
K
-----------
T
N
I
S
Q
S
T
E
Q
E
M
A
S
L
W
S
F
D
D
A
R
---
A
K
A
Q
F
E
E
Y
K
R
N
Y
F
E
G
A
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
40.62
22%
-105
- C2 -
3A4N
6
PSTK_METJA
A:
[7-156]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
---
I
L
T
G
L
P
G
V
G
K
-
S
T
F
S
K
-
N
L
A
-------
K
-----
I
L
-
S
K
N
----
N
--
I
D
V
I
--------------------------
V
L
G
S
D
L
I
---------
R
E
S
F
P
V
WKEK
Y
E
E
F
-
I
K
K
S
-
T
Y
R
L
I
D
S
A
L
K
N
Y
W
--
V
I
V
D
D
T
N
Y
Y
N
S
---------------
M
R
--------
R
D
L
I
N
I
A
---------
K
K
Y
N
K
N
Y
A
I
I
Y
L
K
-
A
-
S
L
D
V
L
I
R
R
N
I
E
-----------
R
G
E
K
I
P
N
-
E
V
I
K
K
M
Y
E
K
-
F
D
E
---
P
G
K
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
40.48
22%
-90
- C2 -
3A4M
4
PSTK_METJA
A:
[7-156]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
---
I
L
T
G
L
P
G
V
G
K
-
S
T
F
S
K
-
N
L
A
-------
K
-----
I
L
-
S
K
N
----
N
--
I
D
V
I
--------------------------
V
L
G
S
D
L
I
---------
R
E
S
F
P
V
WKEK
Y
E
E
F
-
I
K
K
S
-
T
Y
R
L
I
D
S
A
L
K
N
Y
W
--
V
I
V
D
D
T
N
Y
Y
N
S
---------------
M
R
--------
R
D
L
I
N
I
A
---------
K
K
Y
N
K
N
Y
A
I
I
Y
L
K
-
A
-
S
L
D
V
L
I
R
R
N
I
E
-----------
R
G
E
K
I
P
N
-
E
V
I
K
K
M
Y
E
K
-
F
D
E
---
P
G
K
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
40.10
22%
-100
- C2 -
3AM1
2
PSTK_METJA
A:
[7-156]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
---
I
L
T
G
L
P
G
V
G
K
-
S
T
F
S
K
-
N
L
A
-------
K
-----
I
L
-
S
K
N
----
N
--
I
D
V
I
--------------------------
V
L
G
S
D
L
I
---------
R
E
S
F
P
V
WKEK
Y
E
E
F
-
I
K
K
S
-
T
Y
R
L
I
D
S
A
L
K
N
Y
W
--
V
I
V
D
D
T
N
Y
Y
N
S
---------------
M
R
--------
R
D
L
I
N
I
A
---------
K
K
Y
N
K
N
Y
A
I
I
Y
L
K
-
A
-
S
L
D
V
L
I
R
R
N
I
E
-----------
R
G
E
K
I
P
N
-
E
V
I
K
K
M
Y
E
K
-
F
D
E
---
P
G
K
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
39.39
22%
-93
- C2 -
3A4L
5
PSTK_METJA
A:
[7-156]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
---
I
L
T
G
L
P
G
V
G
K
-
S
T
F
S
K
-
N
L
A
-------
K
-----
I
L
-
S
K
N
----
N
--
I
D
V
I
--------------------------
V
L
G
S
D
L
I
---------
R
E
S
F
P
V
WKEK
Y
E
E
F
-
I
K
K
S
-
T
Y
R
L
I
D
S
A
L
K
N
Y
W
--
V
I
V
D
D
T
N
Y
Y
N
S
---------------
M
R
--------
R
D
L
I
N
I
A
---------
K
K
Y
N
K
N
Y
A
I
I
Y
L
K
-
A
-
S
L
D
V
L
I
R
R
N
I
E
-----------
R
G
E
K
I
P
N
-
E
V
I
K
K
M
Y
E
K
-
F
D
E
---
P
G
K
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
38.26
25%
-242
- C2 -
2IUS
-
FTSK_ECOLI
A:
[963-1035]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
L
-
T
V
V
L
G
K
D
I
A
----------------------
G
E
P
V
V
A
D
-----
L
-
A
---------------------
K
M
P
H
L
---
L
V
A
G
T
T
G
S
G
A
-
S
V
G
V
N
-
A
M
I
-------
L
-----
S
M
-
L
Y
K
AQPE
D
--
V
R
F
I
M
I
-
D
P
---
K
M
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
36.71
28%
-182
- C2 -
4GLE
4
?
A:
[76-125]
--------------------------------------------------------------
F
F
R
I
S
S
N
T
I
P
L
A
S
H
P
K
F
H
V----
N
W
K
D
K
L
S
H
I
L
G
D
I
G
D
F
I
K
E
N
S
I
R
I
S
M
H
P
G
Q
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
36.56
28%
-206
- C2 -
3TC3
-
?
A:
[76-125]
--------------------------------------------------------------
F
F
R
I
S
S
N
T
I
P
L
A
S
H
P
K
F
H
V----
N
W
K
D
K
L
S
H
I
L
G
D
I
G
D
F
I
K
E
N
S
I
R
I
S
M
H
P
G
Q
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
36.54
22%
-222
- C2 -
4LYA
2
?
A:
[336-404]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
-
F
I
P
V
G
L
D
E
Q
T
---------------------
V
R
P
V
A
I
N
-----
M
-
R
---------------------
T
D
P
H
C
---
L
I
V
G
Q
S
R
K
G
K
-
T
N
V
V
K
-
V
I
L
-------
E
-----
S
L
-
L
V
Q
E---
P
--
E
S
I
G
L
L
-
D
G
---
I
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
36.40
42%
-173
- C2 -
3DZD
1
?
A:
[130-175]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
V
G
E
H
-----
P
K
I
L
E
I
K
R
--------
L
I
P
K
I
A
K
S
K
A
P
-
V
---
L
I
T
G
E
S
G
T
G
K
-
E
I
V
A
R
-
L
I
H
-------
R
-----
Y
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
Fugue
36.06
14%
-84
- C1 -
4RGL
1
?
A:
[8-335]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
Q
P
P
Y
T
I
T
P
A
I
V
N
---
L
V
--------------
A
E
I
G
E
I
I
----------------
G
R
Y
T
V
L
A
E
Q
N
L
T
P
R
L
R
R
E
N
R
I
R
T
I
Q
A
S
L
A
I
E
N
N
T
L
T
L
E
Q
V
T
A
V
I
D
G
K
R
-----------
V
L
G
H
P
R
E
I
Q
E
V
R
N
-
A
F
A
T
Y
E
A
M
E
D
W
D
---
A
S
V
E
G
D
L
L
A
---------
A
H
---
E
L
L
M
R
G
----
L
V
D
-
E
-----
T
G
R
Y
R
S
G
G
V
G
I
F
RG
E
Q
L
V
H
M
A
P
P
A
D
R
V
P
K
L
M
A
D
L
L
D
W
L
E
N
T
N
E
--------
H
-
P
L
V
A
S
C
I
F
H
Y
E
F
E
F
I
H
-----
P
-
F
---------------------------------
A
D
G
N
G
R
M
G
R
L
W
Q
-
T
L
I
-------
L
R
N
W
KP
L
L
-
A
Y
L
----
P
--
V
E
T
V
I
R
-
D
R
---
Q
E
D
Y
Y
--------
R
V
L
A
V
A
D
S
Q
A
-------------
D
A
T
P
----
F
V
E
F
M
L
G
A
L
-
R
D
A
V
R
E
A
V
S
T
D
H
Q
--
V
T
D
Q
V
A
A
L
I
R
A
---------------
I
G
G
-------
G
E
L
S
S
N
D
L
M
--
Q
A
L
-
G
L
S
H
R
P
T
F
R
N
N
Y
L
N
P
A
M
E
D
E
W
I
E
R
T
--
Q
-----------
P
D
S
P
R
S
P
T
Q
R
Y
R
L
T
G
K
G
-
Q
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
HHSearch
33.13
29%
-164
- C2 -
2IUT
2
FTSK_PSEAE
A:
[204-256]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
R
P
I
I
T
D
-----
L
-
A
---------------------
K
M
P
H
L
---
L
V
A
G
T
T
G
S
G
K
-
S
V
G
V
N
-
A
M
L
-------
L
-----
S
I
-
L
F
K
STPS
E
--
A
R
L
I
M
I
-
D
P
---
K
M
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
30.45
28%
-150
- C2 -
5BQ5
3
ISTB_GEOSE
A:
[38-77]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
K
E
N
I
---
L
F
L
G
P
P
G
I
G
K
-
T
H
L
A
I
-
S
I
G
-------
M
-----
E
A
-
I
A
R
----
G
--
Y
K
T
Y
F
I
-
T
A
---
H
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
30.18
30%
-23
- C2 -
1QVI
3
MYS_ARGIR
A:
[172-272]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
---
L
I
T
G
E
S
G
A
G
K
-
T
E
N
T
K
-
K
V
I
-------
M
-----
Y
L
-
A
K
V
----
A
--
C
A
V
K
------------------------
E
G
S
L
E
D
Q
I
I
---------
Q
A
N
-
P
V
---------
L
E
A
Y
G
N
A
K
T
T
R
N
N
N
S
S
R
F
--
G
K
F
I
R
I
H
F
G
P
T
---------------
G
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
29.59
26%
-54
- C2 -
4PL3
1
ERN1_MOUSE
A:
[283-383]
-----------------------------------------------------------------------------------------------------------
H
V
L
K
H
P
F
F
W
S
L
E
K
Q
L
Q
F
F
Q
-----
D
V
S
D
R
I
E
K
E
A
L
D
------
G
P
I
V
R
Q
L
E
R
G
G
R
A
V
V
K
M
D
W
---------
R
E
N
I
T
V
P
L
Q
T
D
L
R
K
F
R
T
Y
K
G
G
S
V
R
D
L
L
R
A
M
R
N
K
K
H
----
H
Y
R
E
L
P
------
V
E
V
Q
E
--
T
L
G
S
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
53
Fugue
29.46
13%
-85
* C3 *
2JO8
-
STK4_HUMAN
A:
[1-51]
----------------------------------------------------------------------------------------------------
G
---
S
D
Y
E
F
L
K
S
W
T
V
E
D
L
Q
K
R
---
L
L
-----
A
L
D
P
M
M
E
Q
E
I
E
E
I
R
Q
K
Y
Q
S
K
R
Q
P
I
L
D
A
I
E
A
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------