@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu05250: (2016-06-08 )
MKLDEFTIGQVFKTKSLKVSKDDIMRFAGEFDPQYMHVDEEKASKGRFNGIIASGIQTLAISFKLWIEEGFYGDDIIAGTEMNHMTFIKPVYPDDELFTIVEVLDKQPKRNELGILTVLLSTYNQKEVKVFEGELSVLIKR
Atome Classification :
(20 SA)
-----.......--..10..-.-.-....20.......---.30.-........40...-....-.50........60.-....---...70-.-.--.------..-..-..80........90.---.-----......100......--.110----.----..-.....120..---------------.-....-.130.....-..140---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----MKLDEFT--I
G
Q
V
F
K
-T-K-SLKV
S
K
D
D
I
M
R
F
A
---GE-F-DPQ
Y
M
HVDEEKAS-KGRF-N
G
I
I
A
SG
I
Q
T
L
A
I
S
-
F
K
L
W
---
I
EEG--F-Y--G------DD-II-AGTEMN
H
M
T
F
I
KPVY---P-----D
D
E
L
F
T
I
V
E
V
L
DKQP--KRN-----E----
L
G
-
I
L
T
V
L
L
-
S
TY---------------N-Q
K
E
V
-
K
V
FEG
E
L
S
V
-
L
IKR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
89.24
28%
-130
- C5 -
1Q6W
-
?
A:
[20-157]
--------------
I
G
E
K
I
E
-
G
-
L
-
P
R
T
V
T
E
T
D
I
W
T
F
A
Y
L
T
A
D
-
F
-
F
P
--
L
H
T
D
V
E
F
A
K
-
K
T
I
F
-
G
K
P
I
A
Q
G
M
L
V
L
S
I
A
-
L
G
M
V
D
Q
V
I
L
S
N
--
Y
-
D
--
V
------
S
S
-
V
I
-
A
F
F
G
I
K
D
V
R
F
L
R
P
V
F
---
I
-----
G
D
T
I
A
A
S
A
E
V
V
E
K
Q
D
--
F
D
E
-----
K
----
S
G
-
V
V
T
Y
K
L
-
E
V
K
---------------
N
-
Q
R
G
E
-
L
V
L
T
A
L
Y
S
A
-
L
I
R
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
88.87
37%
-108
- C5 -
3EXZ
-
?
A:
[18-142]
-------
L
E
D
L
A
--
V
G
D
R
F
D
-
S
-
A
-
R
H
R
V
E
A
A
A
I
K
A
F
A
---
G
E
-
F
-
D
P
Q
P
F
H
L
D
E
E
A
A
R
-
H
S
L
F
-
G
G
L
A
A
S
G
W
H
T
A
A
I
T
-
M
R
L
L
---
V
T
S
G
--
L
P
L
--
A
------
Q
G
-
I
I
G
A
G
T
E
---
L
S
W
P
N
P
T
R
---
P
-----
G
D
E
L
H
V
E
T
T
V
L
A
I
T
P
SK
S
R
P
-----
D
----
R
A
-
I
V
T
C
Q
S
-
D
T
L
---------------
N
-
Q
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
Fugue
87.25
31%
-91
- C5 -
3EXZ
-
?
A:
[15-160]
----G
L
F
L
E
D
L
A
--
V
G
D
R
F
D
-
S
-
A
-
R
H
R
V
E
A
A
A
I
K
A
F
A
---
G
E
-
F
-
D
P
Q
P
F
H
L
D
E
E
A
A
R
-
H
S
L
F
-
G
G
L
A
A
S
G
W
H
T
A
A
I
T
M
R
L
L
V
---
T
S
G
L
--
P
-
L
--
A
------
Q
G
----
I
I
G
A
G
T
E
L
S
W
P
N
P
T
R
---
P
-----
G
D
E
L
H
V
E
T
T
V
L
A
I
T
P
SK
S
R
P
-----
D
----
R
A
-
I
V
T
C
Q
S
-
D
T
L
---------------
N
-
Q
R
G
E
-
V
V
Q
R
S
T
A
K
V
-
V
V
F
R
RPL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
86.66
30%
-105
- C5 -
3EXZ
-
?
A:
[16-156]
-----
L
F
L
E
D
L
A
--
V
G
D
R
F
D
-
S
-
A
-
R
H
R
V
E
A
A
A
I
K
A
F
A
---
G
E
-
F
-
D
P
Q
P
F
H
L
D
E
E
A
A
R
-
H
S
L
F
-
G
G
L
A
A
S
G
W
H
T
A
A
I
T
-
M
R
L
L
---
V
T
S
---
G
-
L
--
P
------
L
A
-
Q
G
-
I
I
G
A
G
T
E
L
S
W
P
N
P
T
R
---
P
-----
G
D
E
L
H
V
E
T
T
V
L
A
I
T
P
--
S
K
S
RP---
D
----
R
A
-
I
V
T
C
Q
S
-
D
T
L
---------------
N
-
Q
R
G
E
-
V
V
Q
R
S
T
A
K
V
-
V
V
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
80.91
28%
-119
- C5 -
1Q6W
-
?
A:
[14-157]
------
Y
F
E
S
I
Q
--
I
G
E
K
I
E
-
G
-
L
-
P
R
T
V
T
E
T
D
I
W
T
F
A
---
Y
L
T
A
-
D
F
F
P
L
H
T
D
V
E
F
A
K
-
K
T
I
F
-
G
K
P
I
A
Q
G
M
L
V
L
S
I
A
-
L
G
M
V
---
D
Q
V
I
L
S
N
-
Y
D-
V
------
S
S
-
V
I
-
A
F
F
G
I
K
D
V
R
F
L
R
P
V
F
---
I
-----
G
D
T
I
A
A
S
A
E
V
V
E
K
Q
D
--
F
D
E
-----
K
----
S
G
-
V
V
T
Y
K
L
-
E
V
K
---------------
N
-
Q
R
G
E
-
L
V
L
T
A
L
Y
S
A
-
L
I
R
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
74.54
18%
-134
- C5 -
4E3E
-
MCH_CHLAA
A:
[195-350]
------
L
W
D
D
Y
E
--
V
G
E
K
I
D
-
H
V
D
-
G
V
T
I
E
E
A
E
H
M
Q
A
T
---
R
L
Y
Q
-
N
T
A
R
V
H
F
N
L
H
V
E
R
-
E
G
R
F
-
G
R
R
I
V
Y
G
G
H
I
I
S
L
A
-
R
S
L
S
---
F
N
----
G
-
L
--
A
------
N
--
A
L
-
S
I
A
A
I
N
S
G
R
H
T
N
P
S
F
---
A
-----
G
D
T
I
Y
A
W
S
E
I
L
A
K
M
A
--
I
P
G
RT---
D
----
I
G
-
A
L
R
V
R
T
-
V
A
T
K
DRPCHDFPYRDAEG
N
-
Y
D
P
A
-
V
V
L
D
F
D
Y
T
V
-
L
M
P
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
74.02
23%
-133
- C5 -
4RLJ
4
?
B:
[9-143]
-----
R
E
F
S
S
V
K
--
V
G
D
Q
L
P
-
E
-
K
-
T
Y
P
L
T
R
Q
D
L
V
N
Y
A
---
G
V
S
G
-
D
L
N
P
I
H
W
D
D
E
I
A
K
-
V
V
G
L
-
D
T
A
I
A
H
G
M
L
T
M
G
I
G
-
G
G
Y
V
---
T
S
----
W
-
V
--
G
------
D
P
-
G
--
A
V
T
-
E
Y
N
V
R
F
T
A
V
V
P
---
V
P
NDG
K
G
A
E
L
V
F
N
G
R
V
K
S
V
D
P
---
E
-----------
S
K
-
S
V
T
I
A
L
-
T
A
T
---------------
T
-
G
-
G
K
-
K
I
F
-
G
R
A
I
A
-
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
73.19
20%
-109
- C5 -
4FFU
-
?
A:
[29-169]
-----
I
Y
Y
E
D
Y
E
--
Q
G
H
V
R
L
-
T
-
S
-
G
R
T
I
T
E
T
D
F
V
V
H
A
---
G
H
T
G
-
D
F
F
P
H
H
M
D
A
E
F
A
K
-
T
L
P
G
-
G
Q
R
I
A
H
G
T
M
I
F
S
I
G
-
V
G
L
T
---
A
S
----
L
-
I
--
N
-------
P
-
V
A
-
F
S
Y
G
Y
D
R
L
R
F
V
R
P
V
H
---
I
-----
G
D
T
I
R
T
R
V
T
I
A
A
K
E
D
--
D
P
K
RP---
G
----
A
G
-
R
V
V
E
R
C
-
E
V
I
---------------
N
-
Q
R
G
E
-
V
V
L
A
A
D
H
I
L
-
I
V
E
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
Fugue
70.51
21%
-109
- C5 -
1IQ6
1
PHAJ_AERCA
A:
[3-134]
-------
A
Q
S
L
E
--
V
G
Q
K
A
R
-
L
-
S
-
K
R
-
F
G
A
A
E
V
A
A
F
A
---
A
L
-
S
E
D
F
N
P
L
H
L
D
P
A
F
A
A
-
T
T
A
F
-
E
R
P
I
V
H
G
M
L
L
A
S
L
F
-
S
G
L
L
---
G
Q
Q
L
--
P
-
G
--
K
------
G
S
-
I
Y
-
L
G
Q
S
L
---
S
F
K
L
P
V
F
---
V
-----
G
D
E
V
T
A
E
V
E
V
T
A
L
R
E
--
D
K
------------
P
-
I
A
T
L
T
T
-
R
I
F
---------------
T
-
Q
G
G
A
-
L
A
V
T
G
E
A
V
V
-
K
L
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
68.98
24%
-120
- C5 -
3K67
1
?
A:
[31-158]
-----
K
F
E
G
E
L
K
--
E
G
Y
R
F
E
---
Y
-
E
K
K
L
C
E
I
D
V
A
M
F
G
---
L
I
S
G
-
D
L
N
P
V
H
F
D
E
D
F
A
S
-
K
T
R
F
-
G
G
R
V
V
H
G
M
L
T
T
S
L
V
-
S
A
A
V
---
A
R
----
L
----
P
------
G
T
----
V
V
L
L
E
Q
S
F
R
Y
T
S
P
V
R
---
I
-----
G
D
V
V
R
V
E
G
V
V
S
G
V
E
K
----------------
N
-
R
Y
T
I
D
V
-
K
C
Y
---------------
T
--
G
D
K
-
V
V
A
E
G
V
V
K
V
-
L
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
68.05
21%
-110
- C5 -
1IQ6
1
PHAJ_AERCA
A:
[3-134]
-------
A
Q
S
L
E
--
V
G
Q
K
A
R
---
L
-
S
K
R
F
G
A
A
E
V
A
A
F
A
---
A
L
S
E
-
D
F
N
P
L
H
L
D
P
A
F
A
A
-
T
T
A
F
-
E
R
P
I
V
H
G
M
L
L
A
S
L
F
-
S
G
L
L
---
G
Q
----
Q
-
L
--
P
------
G
K
-
G
--
S
I
Y
L
G
Q
S
L
S
F
K
L
P
V
F
---
V
-----
G
D
E
V
T
A
E
V
E
V
T
A
L
R
E
---
D
-----------
K
P
-
I
A
T
L
T
T
-
R
I
F
---------------
T
-
Q
G
G
A
-
L
A
V
T
G
E
A
V
V
-
K
L
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
68.01
23%
-89
- C5 -
5CPG
7
?
A:
[6-138]
-----
I
P
Y
A
E
L
E
--
V
G
Q
K
A
E
---
Y
-
T
S
S
I
A
E
R
D
L
Q
L
F
A
---
A
V
S
G
-
D
R
N
P
V
H
L
D
A
A
Y
A
A
-
T
T
Q
F
-
K
E
R
I
A
H
G
M
L
S
G
A
L
I
-
S
A
A
I
---
A
T
----
V
-
L
--
P
------
G
--
P
G
-
T
I
Y
L
G
Q
T
L
R
F
T
R
P
V
K
---
L
-----
G
D
D
L
K
V
E
L
E
V
L
E
K
L
P
---
K
------------
N
-
R
V
R
M
A
T
-
R
V
F
---------------
N
-
Q
A
G
K
-
Q
V
V
D
G
E
A
E
I
-
M
A
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
65.72
21%
-120
- C5 -
2C2I
-
ECH1_MYCTU
A:
[5-149]
-----
E
S
V
A
D
L
A
A
A
A
G
E
K
V
G
Q
S
-
D
-
W
V
T
I
T
Q
E
E
V
N
L
F
A
---
D
A
T
G
-
D
H
Q
W
I
H
V
D
P
E
R
A
A
-
A
G
P
F
-
G
T
T
I
A
H
G
F
M
T
L
A
L
L
-
P
R
L
Q
---
H
Q
----
M
-
Y
T
V
K
------
G
V
K
L
A
-
I
N
Y
G
L
N
K
V
R
F
P
A
P
V
P
---
V
-----
G
S
R
V
R
A
T
S
S
L
V
G
V
E
D
---
L
G
-----
N
----
G
T
V
Q
A
T
V
S
T
-
T
V
E
---------------
V
E
G
S
A
K
-
P
A
C
V
A
E
S
I
V
-
R
Y
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
65.09
14%
-121
- C5 -
2BI0
1
?
A:
[13-157]
-----
P
Y
F
D
D
L
S
--
K
G
Q
V
F
D
-
W
A
P
-
G
V
T
L
S
L
G
L
A
A
A
H
Q
---
S
I
V
G
-
N
R
L
R
L
A
L
D
S
D
L
C
A
A
V
T
G
M
-
P
G
P
L
A
H
P
G
L
V
C
D
V
A
-
I
G
Q
S
---
T
L
----
A
-
T
---------
Q
R
-
V
K
-
A
N
L
F
Y
R
G
L
R
F
H
R
F
P
A
---
V
-----
G
D
T
L
Y
T
R
T
E
V
V
G
L
R
A
--
N
S
P
KPGR
A
P
----
T
G
-
L
A
G
L
R
M
-
T
T
I
---------------
D
-
R
T
D
R
-
L
V
L
D
F
Y
R
C
A
-
M
L
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
HHSearch
64.20
18%
-113
- C5 -
4E3E
1
MCH_CHLAA
A:
[10-149]
------
F
F
E
D
F
R
--
L
G
Q
T
I
V
H
A
-
T
-
P
R
T
I
T
E
G
D
V
A
L
Y
T
---
S
L
Y
G
-
S
R
F
A
L
T
S
S
T
P
F
A
Q
-
S
L
G
L
-
E
R
A
P
I
D
S
L
L
V
F
H
I
V
-
F
G
K
T
---
V
P
----
D
-
I
--
S
------
L
N
-
A
I
-
A
N
L
G
Y
A
G
G
R
F
G
A
V
V
Y
---
P
-----
G
D
T
L
S
T
T
S
K
V
I
G
L
R
Q
--
N
K
D
G----
K
----
T
G
-
V
V
Y
V
H
S
-
V
G
V
---------------
N
-
Q
W
D
E
-
V
V
L
E
Y
I
R
W
V
-
M
V
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
63.23
16%
-121
- C5 -
4RLJ
7
Y635_MYCTU
A:
[3-145]
-------
L
S
A
D
I
--
V
G
M
H
Y
R
-
Y
-
P
D
H
Y
E
V
E
R
E
K
I
R
E
Y
A
---
V
A
V
Q
-
N
D
D
A
W
Y
F
E
E
D
G
A
A
-
E
L
G
Y
-
K
G
L
L
A
P
L
T
F
I
C
V
F
G
-
Y
K
A
Q
---
A
A
----
F
-
F
--
K
H
A
NIAT
A
E
-
A
Q
-
I
V
Q
V
D
Q
V
L
K
F
E
K
P
I
V
---
A
-----
G
D
K
L
Y
C
D
V
Y
V
D
S
V
R
E
---
A
H
-----
G
----
T
Q
-
I
I
V
T
K
N
-
I
V
T
---------------
N
-
E
E
G
D
-
L
V
Q
E
T
Y
T
T
L
-
A
G
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
Fugue
63.19
19%
-131
* C5 *
4W78
2
?
B:
[1-126]
---------
M
T
V
--
V
G
A
V
L
P
-
E
-
L
-
K
L
Y
G
D
P
T
F
I
V
S
T
A
---
L
A
-
T
R
D
F
Q
D
V
H
H
D
R
D
K
A
V
-
A
Q
G
S
-
K
D
I
F
V
N
-
I
L
T
D
T
G
L
-
V
Q
R
Y
---
V
T
D
W
--
A
-
G
--
P
------
S
-----
A
L
I
K
S
I
G
L
R
L
G
V
P
W
Y
---
A
-----
Y
D
T
V
T
F
S
G
E
V
T
A
V
N
D
----------------
G
-
L
I
T
V
K
V
-
V
G
R
---------------
N
-
T
L
G
--
D
H
V
T
A
T
V
E
L
-
S
M
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
62.23
17%
-142
- C5 -
3IR3
1
HTD2_HUMAN
A:
[14-144]
--------
M
H
I
K
--
V
G
D
R
A
E
---
L
-
R
R
A
F
T
Q
T
D
V
A
T
F
S
---
E
L
T
G
-
D
V
N
P
L
H
L
N
E
D
F
----------
T
I
V
H
G
V
L
I
N
G
L
I
-
S
A
L
L
---
G
T
----
K
-
M
--
P
------
G
P
--
G
-
C
V
F
L
S
Q
E
I
S
F
P
A
P
L
Y
---
I
-----
G
E
V
V
L
A
S
A
E
V
K
K
L
K
R
----------
F
----
I
A
-
I
I
A
V
S
C
-
S
V
I
-----------------
E
S
K
K
-
T
V
M
E
G
W
V
K
V
-
M
V
P
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
61.63
17%
-104
- C5 -
4V12
2
?
A:
[208-342]
------
N
F
D
D
L
K
--
V
G
E
E
L
P
-
V
-
H
-
T
A
R
L
S
R
G
D
L
V
N
Y
A
---
G
V
A
G
-
D
A
N
P
L
H
W
D
E
N
I
A
K
-
L
A
G
Q
-
P
D
V
I
A
H
G
M
L
T
M
G
L
G
-
A
G
F
V
---
S
S
----
W
-
S
--
G
------
D
--
P
G
-
A
I
-
T
R
Y
A
V
R
L
S
Q
P
A
V
V
P
A
E
-----
G
T
E
I
E
Y
S
G
R
I
K
S
L
D
P
---
E
T
-----
R
--------
T
G
V
V
I
-
V
A
A
---------------
K
-
S
G
G
R
K
I
F
G
L
A
T
A
T
I
-
R
F
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
Fugue
58.13
15%
-94
- C5 -
2BI0
1
?
A:
[8-337]
IRVGG
P
Y
F
D
D
L
S
--
K
G
Q
V
F
D
W
A
-
P
-
G
V
T
L
S
L
G
L
A
A
A
H
Q
---
S
I
-
V
G
N
R
L
R
L
A
L
D
S
D
L
C
A
-
A
V
T
G
M
P
G
P
L
A
H
P
G
L
V
C
D
V
A
-
I
G
Q
S
---
T
L
------
A
--
T
------
Q
R
-
V
K
-
A
N
L
F
Y
R
G
L
R
F
H
R
F
P
A
---
V
-----
G
D
T
L
Y
T
R
T
E
V
V
G
L
R
A
--
N
S
P
-----
K
PGR
A
P
T
-
G
L
A
G
L
R
M
T
T
I
---------------
D
-
R
T
D
R
-
L
V
L
D
F
Y
R
C
A
M
L
P
A
S
PDWKPGAVPGDDLSRIGADAPAPAADPTAHWD
G
A
V
F
R
K
R
VPGPHFDAGIAG
A
V
L
H
S
T
A
D
L
VSG
A
P
E
L
A
R
L
T
LNIAATHHDWRVSGRRLVY
G
G
H
T
I
G
L
A
L
A
Q
A
T
R
L
L
PNLATVL
D
W
E
S
CDHT
A
P
V
H
EG
D
T
L
Y
S
E
L
H
IE
S
A
Q
A
H
AD
G
G
V
L
G
L
R
S
L
V
Y
A
V
S
DSAS
E
P
D
R
Q
V
L
D
W
R
F
S
A
L
Q
F