@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu05430: (2016-06-08 )
MSKMLYTLGGWVARNRIKAICAWIVVLVAAIGLAVTLKPSFSEDMSIPDTPSEKAMDVIQKEFPHGPDKGSIRVIFGAGDGEKLTGKPAKKAIEDTFKEISKDDSVDSIASPFVTGTIAKDGTVAYADIQYKSSADDIKDYSIKHLKDSLKMADDEGLQTELSGDVPGAEMEIGGVSEIVGIILAFVVLAITFGSLLIAGLPILTALIGLGVSIGLVLIGTQVFDIASVSLSLAGMIGLAVGIDYALFIFTKHRQFLGEGIQKNESIARAVGTAGSAVVFAGLTVIVALCGLTVVNIPFMSAMGLTAGLSVLMAVLASITLVPAVLSIAGKRMIPKSNKKIEKQSTETNVWGRFVTKNPIMLSVCSILILIVISIPSMHLELGLPDAGMKAKDNPDRRAYDLLAEGFGEGFNGQLTIVADATNATENKAEAFADAVKEIKGLDHVASVTPAMPNKEGNFAIITVVPETGPNDVTTKDLVHDVRSLSDKNGVDLLVTGSTAVNIDISDRLNDAIPVFAVLIVGFAFVLLTIVFRSLLVPLVAVAGFMLTMTATLGICVFVLQDGNLIDFFKIPEKGPILAFLPILSIGILFGLAMDYQVFLVSRMREEYVKTNNPVQAIQAGLKHSGPVVTAAGLIMIFVFAGFIFAGEASIKANGLALSFGVLFDAFIVRMTLIPSVMKLMGNAAWYLPKWLDKIIPNVDIEGHQLTKEIQPEIDHEQKKQISV
Atome Classification :
(20 SA)
.........10........20.-.......30........40........50........60........70........80........90........100.......110.......120.......130.......-140.......150--.---......160----.......170-.--........180....-...190.......200.......210.......220.---------......230.......240.......250......-.-----------260.......270.......280.......290..---.---..---..300.......310.....---..320....-----...330------.......340.----.---.-------.-------.....350.......360.......370.......380..----...---------.---------.---------390.......400-.---.----------------...---------------..--------..-------------------410-------.--.......-.--------------------------------------------------------420...-----------------------------------------------------.--.----..----430------------------------------------------........--------------------------------------------------.440--..-.....450------.----------.-----------------------------------------.------------------.-------------------------------.---------------------.----------...460.......----------------------------------------------------470---------------------------------------------------.-----------------------------------------..---------------------------------------------------......480--......--.------.490.......500.......510.......520.......530.......540.......550.......560.....----...570.......580----.......-------590.......600.......-610.........620.......630.......640....---.---.---.650.......660.......670.......680.......690.......700........710.......720..------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MS
K
M
L
Y
TLG
G
W
V
A
R
N
R
I
K
A
I
C
A
-
W
I
V
V
L
V
A
A
IG
L
A
V
T
LKPSFSEDMSIPDTP
S
E
K
A
M
D
V
I
Q
K
EFPHGPDKG
S
I
R
V
I
F
GAGDGEKLTGK
P
A
K
K
A
I
E
D
T
F
K
E
ISKDDS
V
D
S
I
ASP
F
V
T
G
T
IAKD
G
T
V
A
Y
A
D
I
Q
YKSSADD
I
K
-
D
Y
S
I
K
H
L
K
D
S
LKM--A---DDEGLQTEL----SGDVPGAE---M--EIG
G
V
S
E
I
V
G
I
I
L
A
F
-
V
V
L
A
I
T
F
G
S
L
L
I
A
G
L
P
I
L
T
A
L
I
G
L
G
V
S
I
G
L
V
L
IGT
Q
V
---------
F
D
I
A
S
V
S
L
S
L
A
G
M
I
G
L
A
V
G
I
D
Y
A
L
F
I
F
T
K
H
R
Q
F
L
G
-
E
-----------
G
I
QK
N
E
S
I
A
R
A
VGTA
G
S
A
V
V
F
A
G
L
T
V
I
V
A
L
C
G
L
T
V
---V---N
I
---
P
F
M
S
A
M
G
L
T
A
G
L
S
V
L
M
A
V
L
A
---
S
I
T
L
V
P
A
V
L
-----
S
I
AGKR------MIPKSNKK--I----E---K-------Q-------STETN
V
W
G
R
FVTKN
P
I
M
L
S
V
C
S
I
L
I
L
I
V
ISIP
S
M
H
L
E
LGL----PDA---------G---------M---------KAKDNP
D
R
R
A
Y
---
D
---
L
----------------
L
A
E
---------------
G
F--------GE-------------------G---------F--NG
Q
L
T
I
V
-
A
--------------------------------------------------------DATNAT-----------------------------------------------------E--
N
----
K
A
----
E
--------------------------------------------
A
F
A
D
A
V
K
E
--------------------------------------------------
I
KGL--
D
H
-
V
A
SVTP--------A----------M-----------------------------------------P------------------N-------------------------------K---------------------E----------G
N
F
A
I
I
T
VVPETG----------------------------------------------------P-----------------------------------------------------N-----------------------------------------DV---------------------------------------------------
T
T
K
D
L
V
H
D
---
V
R
S
LSD--K------NG
V
D
L
L
V
TGS
T
A
V
N
I
D
ISDRLND
A
I
P
V
F
A
V
L
I
V
G
F
A
F
V
L
L
T
I
V
F
R
S
L
L
V
P
L
V
A
V
A
G
F
M
L
T
M
T
A
T
L
G
I
C
V
F
V
L-QDG
N
L
I
----
D
F
F
KIPEKG
P
I
L
A
F
L
P
----
I
L
S
I
G
I
L
-------
F
G
LA
M
D
Y
Q
V
F
L
V
S
R
M
R
E
E
Y
V-K--TNN
P
V
Q
A
I
Q
A
G
LKHSGP
V
V
T
A
A
G
L
I
M
I
F
V
F
A
G
F
I
FA---G---E---A
S
I
KAN
G
L
A
L
S
F
G
V
L
F
D
A
F
I
V
R
M
T
L
I
P
S
V
M
K
L
MGNAA
W
Y
L
P
K
W
L
D
K
IIPNVDI-EG
H
Q
L
T
K
E
IQPEI
D
H
E
Q
K
KQISV------------
22
HHSearch
79.31
14%
-184
- C2 -
4MT1
-
?
A:
[302-1040]
-------------------------------------------------------------------------------------------------------------------------------------------------
K
A
V
K
E
R
L
A
V
--
L
E
K
Y
F
P
Q
G
M
S
W
K
T
----
P
Y
D
T
S
K
F
V
E
I
S
I
--
E
K
V
I
H
T
L
I
E
A
M
V
L
V
F
-
V
V
M
Y
L
F
L
Q
N
I
R
Y
T
L
I
P
T
I
V
V
P
I
S
L
L
G
G
F
A
F
I
S
Y
M
G
M
-----------
S
I
N
V
L
T
M
F
A
M
-
I
L
V
I
G
I
V
V
D
D
A
I
V
V
V
E
N
V
E
R
I
M
A
G
E
-----------
G
L
P
P
K
E
A
T
K
K
A
M
G
Q
I
S
G
A
V
I
G
I
T
A
V
L
I
S
V
F
V
P
L
A
M
---
F
SG
A
A
G
---
N
I
Y
K
Q
F
A
L
T
M
A
S
S
I
A
F
S
A
F
L
---
A
L
T
L
T
P
A
L
C
-----
A
T
------------------G
F
F
G
W
F
N
K
K
F
D
S
-------
W
-------
T
H
G
Y
E
G
R
V
A
K
V
L
R
K
T
F
R
M
M
V
V
Y
I
G
L
A
V
V
G
V
F
L
F
M
R
L
P
T
S
F
----
L
P
T
EDQG
F
V
M
V
S
V
---------
Q
---------
L
P
A
G
A
T
K
E
R
T
D
---
A
T
L
A
Q
----------------
V
T
Q
---------------
L
A
--------
K
S
-------------------
I
---------
P
E-
I
E
N
I
I
T
V
-
S
GFSFSGSGQN
M
A
M
G
F
A----------------------------------------
I
F
K
D
W
N
-----------------------------------------------------
E
RT
A
SGSD
A
V
----
A
--------------------------------------------
V
A
G
K
L
T
G
M
M
M
G
TLKD
G
F
G
I
A
V
V
P
P
PILELG
S
G
L
S
I
N
L
Q
D
RNNTG
H
T
A
L
L
A
K
R
N
E
L
I
Q
K
M
R
A
S
GL
F
D
-
P
S
T
V
R
A
G
G
L
E
D
S
P
Q
L
K
I
--------
D
-----------------------------------------
I
------------------
N
-------------------------------
R
A
A
A
A
A
QGIS
F
A
D
I
R
T
A
L
A
S
A
L
S
S
S
Y
V
S
D
F
P
N
Q
G
R
L
Q
R
V
M
V
Q
A
D
E
D
----------------------------------------------------
A
RMQPADILNLTVPNKSG
V
A
V
P
LSTI
A
T
V
S
W
E
N
G
T
E
Q
S
V
R
F
NG
Y
P
S
M
K
L
S
A
S
PA
T
-----------------------------------------
G
V
---------------------------------------------------
S
T
G
Q
A
M
E
A
---
V
Q
K
M
V
D
E
L
G
------
G
G
Y
S
F
E
W
G
G
Q
S
S
E
E
A
----
K
G
G
S
Q
T
L
I
L
Y
G
L
A
V
A
A
V
F
L
V
L
A
A
L
Y
E
S
W
S
I
P
L
A
V
I
L
V
I
P
L
G
L
I
G
A
A
A
G
V
T
G
R
N
L
F
E
G
L
L
G
----
S
V
P
S
F
A
-----
N
D
I
Y
F
----
Q
V
G
F
V
T
V
-------
M
G
L
S
A
K
N
A
I
L
I
I
E
F
A
K
D
L
Q
A
-
Q
--
G
K
S
A
V
E
A
A
L
E
A
A
R
L
R
F
R
P
I
I
M
T
S
F
A
F
I
L
G
V
V
P
L
Y
I
A
AGA
S
---
S
---
A
S
Q
R
A
I
G
T
T
V
F
W
G
M
L
V
-
G
T
L
L
S
V
F
L
V
P
L
F
Y
V
V
V
R
K
F
F
----------------------------------------------------
19
HHSearch
75.62
14%
-181
- C2 -
4DX5
10
ACRB_ECOLI
A:
[304-1038]
-------------------------------------------------------------------------------------------------------------------------------------------------
A
A
I
R
A
E
L
A
K
--
M
EPF
F
P
S
G
L
K
I
V
Y
----
P
Y
D
T
T
P
F
V
K
I
S
I
--
H
E
V
V
K
T
L
V
E
A
I
I
L
V
F
-
L
V
M
Y
L
F
L
Q
N
F
R
A
T
L
I
P
T
I
A
V
P
V
V
L
L
G
T
F
A
V
L
A
A
F
G
F
-----------
S
I
N
T
L
T
M
F
G
M
V
L
A
-
I
G
L
L
V
D
D
A
I
V
V
V
E
N
V
E
R
V
M
A
-
E
E----------
G
L
P
P
K
E
A
T
R
K
S
M
G
Q
I
Q
G
A
L
V
G
I
A
M
V
L
S
A
V
F
V
P
M
A
F
FGG
S
---
T
G
---
A
I
Y
R
Q
F
S
I
T
I
V
S
A
M
A
L
S
V
L
V
---
A
L
I
L
T
P
A
L
C
-----
A
T
M
L
K
P
------
I
A
K
G
D
H
G
E
G-
K
KG
F
F
G
---
W
-------
F
N
R
M
F
E
K
S
T
H
H
Y
T
D
S
V
G
G
I
L
R
S
T
G
R
Y
L
V
L
Y
L
I
I
V
V
G
M
A
Y
L
F
V
R
L
P
S
S
F
----
L
P
D
---------
E
DQG
V
F
M
T
M
V
Q
---------
L
P
A
G
A
T
Q
E
R
T
Q
---
K
---
V
----------------
L
N
E
V
T
H
Y
Y
L
TKEKNNVE
S
V
F
A
V
N
GFGFA
G
R
-------------------
G
Q--------
N
--
T
G
I
A
F
V
S
-
L
--------------------------------------------------------
K
D
W
A
D
R
PGEENK
V
----------------------------------------------
E
--
A
----
I
T
M
R
A
T
R
A
F
S
QIKD
A
M
V
F
A
F
N
L
P
AIVELGTAT
G
F
D
F
E
L
I
DQAGLG
H
E
K
L
T
Q
A
R
N
Q
L
L
A
E
--------------------------------------------------
A
A
K
H
--
P
D
M
L
T
S
V
R
P
NGL
E
D
T
P
Q
F
----------
K
I
D
I
D
Q
E
K
A
Q
A
L
G-----------------------------
V
S
I
N
D
I
N
T
T
L
G
A
A
WGGSYV
N
D
F
I
----------------------------
D
---------------------
R
----------
G
R
V
K
K
V
Y
V
M
S
E
A
K
----------------------------------------------------
Y
RMLPDDIGD
W
Y
V
R
A
A--------------------------------------
D
G
Q
M
V
P
F
S
A
F
S
S
S
R
W
E
Y
G
S
P
R
L
E
R
Y
NG
L
P
S
M
E
I
L
G
Q
A
A
PGKS
T
G
---------------------------------------------------
E
A
M
E
L
M
E
Q
---
L
A
S
K
L
---
P
------
T
G
V
G
Y
D
W
T
G
M
S
Y
Q
----
E
R
L
S
G
N
Q
A
P
S
L
Y
A
I
S
L
I
V
V
F
L
C
L
A
A
L
Y
E
S
W
S
I
P
F
S
V
M
L
V
V
P
L
G
V
I
G
A
L
L
A
A
T
---------------
F
R
G
L
T
-----
N
D
V
Y
F
----
Q
V
G
L
L
T
T
-------
I
G
L
S
A
K
N
A
I
L
I
V
E
F
A
K
D
L
M
D
K
E
--
G
K
G
L
I
E
A
T
L
D
A
V
R
M
R
L
R
P
I
L
M
T
S
L
A
F
I
L
G
V
M
P
L
V
I
S
---
T
---
G
AG
S
G
A
Q
N
A
V
G
T
G
V
M
G
G
M
V
T
-
A
T
V
L
A
I
F
F
V
P
V
F
F
V
V
V
R
R
R
F
S
R
K
N
E
-----------------------------------------------
20
HHSearch
74.89
13%
-187
- C2 -
3W9I
3
MEXB_PSEAE
A:
[304-1030]
-------------------------------------------------------------------------------------------------------------------------------------------------
K
A
I
R
Q
T
I
A
N
--
L
EPF
M
P
Q
G
M
K
V
V
Y
----
P
Y
D
T
T
P
V
V
S
A
S
I
--
H
E
V
V
K
T
L
G
E
A
I
L
L
V
F
-
L
V
M
Y
L
F
L
Q
N
F
R
A
T
L
I
P
T
I
A
V
P
V
V
L
L
G
T
F
G
V
L
A
A
F
G
F
-----------
S
I
N
T
L
T
M
F
G
M
V
L
A
-
I
G
L
L
V
D
D
A
I
V
V
V
E
N
V
E
R
V
M
A
E
E
-----------
G
L
S
P
R
E
A
A
R
K
S
M
G
Q
I
Q
G
A
L
V
G
I
A
M
V
L
S
A
V
F
L
P
M
A
F
FGG
S
---
T
G
---
V
I
Y
R
Q
F
S
I
T
I
V
S
A
M
A
L
S
V
I
V
---
A
L
I
L
T
P
A
L
C
-----
A
T
M
L
K
P
-----------------F
F
--
G
---
W
F
N
R
M
F
L
S
T
-------
T
H
G
Y
E
R
G
V
A
S
I
L
K
H
R
A
P
Y
L
L
I
Y
V
V
I
V
A
G
M
I
W
M
F
T
R
I
P
T
A
F
----
L
P
D
---------
E
---------
D
QG
V
L
F
A
Q
V
Q
T
P
P
G
S
S
A
E
R
T
Q
V
V
V
D
---
S
----------------
M
R
E
---------------
Y
L
--------
L
E
KESSSVS
S
V
F
T
V
T
GFNFAG
R
---------
G
QS
S
G
M
A
F
I
M
-
L
--------------------------------------------------------
K
P
W
E
E
R
PGGENSV
F
E
L
A
K
R
A
Q
MHFFSFKDAMV
F
A
F
A
P
P
SVLELGNAT
G
F
D
L
F
L
Q
D
QAGV
G
H
E
V
----
L
L
----
Q
--------------------------------------------
A
R
N
K
F
L
M
L
--------------------------------------------------
A
A
Q
N
--
P
A
-
L
Q
R
V
R
P
--------
N
GMSD
E
P
Q
Y
K
L
E
-----------------------------------------
I
------------------
D
D
E
K
A
S
A
L
GVS
L
A
D
I
N
S
T
V
S
I
A
WGSSYV
N
D
F
I
D
---------------------
R
----------
G
R
V
K
R
V
Y
L
Q
G
R
P
D
----------------------------------------------------
A
RM---------------------------------------------------
N
-----------------------------------------
P
D
D
L
S
K
W
Y
V
R
N
DKG
E
M
V
P
FNAF
A
T
G
K
W
E
Y
G
S
P
K
L
E
R
Y
NG
V
P
A
M
E
I
L
G
E
P
APGL
S
S
G
D
A
M
A
A
---
V
E
E
I
V
K
QL
P
------
K
G
V
G
Y
S
W
T
G
L
S
Y
----
E
E
R
L
S
G
-
Q
A
P
A
L
Y
A
L
S
L
L
V
V
F
L
C
L
A
A
L
Y
E
S
W
S
I
P
F
S
V
M
L
V
V
P
L
G
V
I
G
A
L
L
A
T
S
---------------
M
R
G
L
S
-----
N
D
V
F
F
----
Q
V
G
L
L
T
T
-------
I
G
L
S
A
K
N
A
I
L
I
V
E
F
A
K
E
L
H
E
-
Q
--
G
K
G
I
V
E
A
A
I
E
A
C
R
M
R
L
R
P
I
V
M
T
S
L
A
F
I
L
G
V
V
P
L
A
I
S
---
T
---
G
A
G
S
G
S
Q
H
A
I
G
T
G
V
I
G
G
M
V
T
-
A
T
V
L
A
I
F
W
V
P
L
F
Y
V
A
V
S
T
L
-----------------------------------------------------
23
HHSearch
70.54
13%
-193
- C2 -
4K0J
1
?
A:
[312-1018]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
P
K
D
V
K
V
V
P
----
Y
I
D
R
S
N
L
V
D
A
T
V
--
H
T
V
G
K
T
L
M
E
G
M
F
L
V
S
-
L
V
L
L
L
F
L
G
S
P
R
A
A
I
I
V
A
V
T
I
P
L
S
L
L
M
A
F
I
L
M
H
H
F
K
I
-----------
P
A
N
L
L
S
L
--
G
A
I
D
-
F
G
I
I
V
D
G
A
I
V
V
M
E
N
I
L
R
R
R
--------------------
D
I
M
Q
S
V
L
Q
V
A
R
P
I
F
F
G
M
I
V
I
I
T
A
Y
L
P
L
F
A
FQR
I
---
E
Y
---
K
L
F
S
P
M
A
F
A
V
G
F
A
L
F
G
A
L
L
V
---
A
L
L
L
I
P
G
L
A
------------------------
A
--
L
----
V
---
W
-------
L
-------
A
P
R
Y
E
S
V
L
N
R
---
S
T
R
T
A
I
G
I
A
V
A
T
L
V
G
V
M
I
L
G
A
T
I
G
R
D
F
LPYL
D
E
G
S
I
W
L
Q----
V
---------
T
---------
L
P
P
G
I
S
L
E
K
A
G
---
Q
---
M
A
D
N
L
R
A
A
T
M
EFPEVE
H
V
V
T
---------------
Q
V
--------
G
R
-------------------
N
DEGTDPFSP
S
--
H
I
E
T
A
V
T
-
L
H
PYSTWTSGRD
K
Q
Q
L
I
E
A
M
A
T
R
F
R
D
LPG
T
Q
V
G
F
S
Q
P
M
I
D
G
V
L
D
K
L
AGAHSD
L
V
V
K
V
Y
G
N
D
F
------------------------------------------------------
A
--
E
----
T
R
----
Q
--------------------------------------------
V
A
T
A
I
T
R
L
--------------------------------------------------
L
K
T
V
--
P
G
-
A
Q
D
V
I
I
--------
D
----------
Q
E
P
P
L
P
Q
V
R
I
D
V
D
R
A
A
A
A
R
L
GIN
V
A
D
V
M
A
L
I
Q
T
G
IGGSPV
T
Q
V
------------------
F
-------------------------------
V
---------------------
E
----------
D
R
S
Y
N
V
V
A
R
F
I
G
S
SRND
P
E
A
I
G
N
L
T
L
T
A
ANG
A
H
V
A
LAQV
A
H
I
R
L
A
E
G
E
TTITREMN
K
R
H
L
T
V
R
L
N
L
-----------------------------------------------------
R
-----------------------------------------
G
R
---------------------------------------------------
D
L
S
T
F
L
E
E
---
A
R
M
R
I
D
--
K
EVPYDR
T
H
I
Q
V
A
W
G
G
Q
----
F
E
N
Q
Q
R
A
Q
A
R
L
A
V
I
L
P
M
V
L
A
L
M
F
V
L
L
F
-------
Q
P
A
L
I
L
M
A
V
P
L
A
T
L
G
G
L
V
A
L
H
---------------
L
R
G
M
T
-----
L
N
V
S
S
----
A
V
G
F
I
A
L
-------
F
G
V
A
V
L
N
A
I
I
M
I
A
N
L
-------------
K
E
A
V
V
R
G
A
G
E
R
M
R
P
V
L
M
T
A
T
V
A
A
L
G
L
I
P
A
A
L
A
---
H
GLG
S
---
D
V
Q
R
P
L
A
T
V
V
V
G
G
L
I
T
-
A
T
A
L
T
L
V
L
L
P
A
L
Y
Y
L
I
E
T
R
-----------------------------------------------------
34
Fugue
65.31
15%
-87
* C4 *
4XR7
-
PAN2_YEAST
A:
[340-1097]
M
L
A
Y
P
D
Y
F
N
D
I
T
S
D
G
P
I
S
V
D
D
E
T
Y
P
L
S
S
V
G
M
P
Y
Y
L
D
K
L
L
S
A
W
P
P
V
V
F
K
S
E
G
T
I
P
Q
L
L
A
V
I
S
S
Q
N
E
K
L
S
T
Q
E
F
P
L
L
R
Y
D
R
T
K
Y
G
M
R
N
A
I
P
D
Y
V
C
L
R
D
I
R
K
Q
I
T
S
G
L
E
T
S
D
I
Q
T
--------------
Y
T
S
I
N
K
Y
E
V
P
P
A
Y
S
-
R
L
P
L
T
F
D
F
T
P
F
N
N
--
T
---
E
Y
S
G
L
D
P
D
V
----
D
N
H
-----------------
Y
T
N
A
I
I
Q
L
Y
-
R
F
I
P
E
M
F
N
F
V
V
G
C
-------
L
K
D
E
N
F
E
T
T
L
L
T
D
L
G
Y
L
---------
F
D
M
M
E
R
S
---
H
G
K
I
C
S
S
S
N
F
Q
A
S
L
K
S
L
T
D
K
L
E
S
L
C
-
I
-----------
R
E
S
I
E
D
S
S
E
S
I
K
R
N
M
P
Q
K
F
N
R
F
L
L
S
Q
L
I
K
E
E
A
Q
T
V
---
N
H--
N
I
---
T
L
N
Q
C
F
G
L
E
T
E
I
R
T
E
C
S
C
D
H
Y
D
T
T
V
K
L
L
P
S
L
S
I
S
---
G
I
N
K
Q
N
------
I
L
P
Y
I
E
Y
A
--
M
--------
K
-------
N
-------
V
T
Q
K
N
S
I
C
P
T
C
G
K
T
E
T
I
T
Q
E
C
T
V
K
N
L
P
--
S
V
L
S
L
E
L
S
L
-
L
----
D
T
E
---------
F
---------
S
---------
N
I
R
S
S
K
N
-------
W
---
L
----------------
T
S
E
---------------
F
Y
--------
G
S
-------------------
I
---------
I
--
K
N
K
A
V
L
R
-
S
--------------------------------------------------------
T
A
S
E
L
K
-----------------------------------------------------
G
--
T
----
S
H
----
I
------------------------------------------------
F
K
Y
E
--------------------------------------------------
L
N
G
----
Y
-
V
A
K
I
T
---------------------------------------------------------------------------------
D
-------------------------------
N
---------------------
N
----------
N
E
T
R
L
V
T
Y
V
K
K
Y
N
----------------------------------------------------
P
-----------------------------------------------------
K
-----------------------------------------
E
N
---------------------------------------------------
C
F
K
W
L
M
F
N
D
Y
L
V
V
E
I
T
E
--
E
------
E
A
L
K
M
T
Y
P
W
K
T
P
E
I
I
I
Y
C
D
A
E
E
L
R
K
P
F
F
S
V
D
T
Y
S
I
N
Y
---
D
I
L
F
R
D
Y
F
-
A
N
A
R
R
E
Y
K
L
L
T
H
D
E
A
P
K
S
G
T
L
V
A
-
I
D
A
E
F
V
S
L
Q
S
E
L
C
E
I
D
H
Q
G
I
R
S
I
I
R
P
K
R
T
A
L
A
R
I
S
I
I
RGEEGEL
Y
G
V
P
F
V
D
D
Y
V
V
N
T
N
H
I
E
D
Y
L
-
T
--
R
Y
S
G
I
L
P
G
D
L
D
P
E
K
S
T
K
R
L
V
R
R
N
V
V
Y
R
K
V
W
--
L
L
M
Q
---
L
---
G
---
C
V
F
V
G
H
G
L
N
N
D
F
K
H
I
-
N
I
N
V
P
R
N
Q
I
R
D
T
A
I
Y
F
L
Q
G
K
R
Y
L
S
L
R
Y
L
A
Y
V
L
L
G
M
N
I
Q
E
G
N
H
D
S
I
E
D
A
H
T
A
L
I
L
Y
K
K
Y
L
H
L
KEKAIFEKVLNS
24
HHSearch
64.34
11%
-160
- C2 -
3AQP
-
SECDF_THET8
A:
[274-726]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
I
R
S
A
L
I
G
T
L
A
I
F
-
L
L
I
F
A
Y
Y
G
-
P
H
L
G
L
V
A
S
L
G
L
L
Y
T
S
A
L
I
L
G
L
L
S
G
L
G
A
-----------
T
L
T
L
P
G
I
A
G
L
-
V
L
T
L
G
A
A
V
D
G
N
V
L
S
F
E
R
I
K
E
E
L
R
-
A
-----------
G
K
K
L
R
Q
A
I
P
E
G
F
R
H
S
T
L
T
I
M
D
V
N
I
A
H
L
L
A
A
A
A
L
Y
Q
---
Y
---
A
T
---
G
P
V
R
G
F
A
V
I
L
A
I
G
V
V
A
S
V
F
S
---
N
L
V
F
S
R
H
L
L
-----
E
R
L
A
D
R
------
G
E
I
R
P
P
M
W
--
L
---------------------------
V
D
P
R
F
N
F
M
-
G
P
A
R
Y
V
T
A
A
T
L
L
L
A
A
L
A
A
G
V
V
F
A
K
G
F
N
Y
----
S
I
-----------------------------------------------------------------------------------
D
F
--------
T
G
-------------------
G
-------------
T
A
Y
T
L
R
-
A
--------------------------------------------------------
E
P
N
V
E
------------------------------------------------------------------------------------------------------------------
V
E
T
L
R
R
F
--------------------------------------------------
L
E
E
K
--
G
F
-
P
G
K
E
A
V
--------
I
T
Q
--------
V
-------------------------------------------------------------------------------------------------------------------------------
Y
R
E
F
L
V
K
L
P
P
L
----------------------------------------------------------------------------------------------------------
S
-----------------------------------------
D
E
---------------------------------------------------
R
R
----
L
E
---
L
E
R
L
F
A
--
S
-------
E
L
K
A
T
V
L
A
S
E
T
V
G
P
A
I
G
E
E
L
R
R
N
A
V
M
A
V
L
V
G
L
G
L
I
L
L
Y
V
A
F
R
F
-
D
W
T
F
G
V
A
S
I
L
A
V
A
H
D
V
A
I
V
A
G
M
Y
S
---------------
L
L
G
L
E
-----
F
S
I
P
T
----
I
A
A
L
L
T
I
-------
V
G
Y
S
I
N
D
S
I
V
V
S
D
R
I
R
E
N
Q
K
-
L
LR
H
L
P
Y
A
E
L
V
N
R
S
I
N
Q
T
L
S
R
T
V
M
T
S
L
T
T
L
L
P
I
L
A
L
L
F
L
---
G
---
G
---
S
V
L
R
D
F
A
L
A
I
F
V
G
I
F
V
-
G
T
Y
S
S
I
Y
V
V
S
A
L
V
V
A
W
K
N
R
-----------------------------------------------------
37
Fugue
64.32
15%
-57
* C3 *
1ZRO
11
?
A:
[8-601]
N
E
V
L
S
N
C
---
R
E
K
R
K
G
M
K
W
D
C
K
-
K
K
N
D
R
S
N
Y
V
C
I
P
D
R
R
I
Q
L
C
I
V
N
L
A
I
I
K
T
Y
T
K
E
T
M
---
K
D
H
F
I
E
A
S
K
K
E
S
Q
L
L
L
K
K
N
D
N
-------
K
Y
N
S
K
F
C
N
D
L
K
N
S
F
L
D
Y
G
H
L
A
M
G
N
D
M
D
F
G
G
Y
S
T
K
A
E
N
K
I
Q
E
V
-
F
K
G
A
H
G
E
I
S
-
E
H
K
I
K
N
F
R
K
K
W
W
N
--
E
---
F
R
E
K
L
W
E
A
M
----
L
-----
S
E
---
H
--
K
N
N
I
C
K
N
I
P
Q
E
E
L
Q
I
-
T
Q
W
I
K
E
W
H
G
E
F
L
L
E
R
D
N
R
A
K
L
P
K
S
K
C
K
------
N
N
A
L
---------
Y
E
A
C
E
---------------
K
E
C
I
D
P
C
M
K
Y
R
D
W
I
I
-
R
-----------
S
K
F
E
W
H
T
L
S
K
E
Y
E
T
Q
K
V
P
K
E
N
A
E
N
Y
L
I
K
I
S
E
N
K
N
D
---
A
---
K
V
---
S
L
L
-
L
N
N
C
D
A
E
Y
S
K
Y
C
D
C
K
H
---
T
T
T
L
V
K
S
V
L
N
GNDN
T
I
K
E
K
R
E
HID
L
D
D
F
S
K
F
G
C
D
--
K
----
N
---
S
-------
V
-------
D
T
N
T
K
V
W
---
E
C
K
K
P
Y
K
L
S
T
K
D
------
V
C
V
P
P
R
R
Q
E
L
C
L
----
G
N
I
---------
D
---------
R
---------
I
Y
D
K
N
L
L
M
I
K
E
---
H
---
I
----------------
L
A
I
---------------
A
I
--------
Y
E
-------------------
S
---------
R
--
I
L
K
R
K
Y
K
N
K
--------------------------------------------------------
D
D
K
E
V
C
-----------------------------------------------------
K
--
I
----
I
N
----
K
--------------------------------------------
T
F
A
D
I
R
D
I
--------------------------------------------------
I
G
G
T
--
D
Y
-
W
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
-----------------------------------------
D
L
---------------------------------------------------
S
N
R
K
L
V
G
K
---
I
N
T
N
S
N
--
Y
------------
V
H
R
N
K
Q
N
D
K
L
F
R
D
E
W
W
K
V
I
K
K
D
V
W
N
V
I
S
W
V
F
K
D
K
T
V
C
K
E
D
D
I
E
N
I
P
Q
F
F
R
W
F
S
E
W
G
D
D
-----
Y
C
Q
-
D
K
T
K
M
I
----
E
T
L
K
V
E
C
C
E
D
--------------
D
N
C
-------
K
R
K
C
N
S
Y
K
E
W
I
-
S
K
K
K
E
E
Y
N
-
K
--
Q
A
K
Q
Y
Q
E
Y
Q
K
G
N
N
Y
K
----------------------------------------------
M
Y
S
E
F
K
S
I
------------
K
P
E
V
Y
L
K
K
Y
S
E
K
C
-
S
N
L
N
F
-
E
D
-
E
F
K
E
E
L
H
S
D
Y
K
N
K
C
T
M
C
P
E
V
------------
27
HHSearch
54.36
17%
-193
- C2 -
4MT1
-
?
A:
[839-1040]
-------------------------------------------------------------------------------------------------------------------------------------------------
E
A
V
Q
K
M
V
D
E
------
L
G
G
G
Y
S
F
E
W
----
G
G
Q
S
S
E
E
A
---
K
GG
S
Q
T
L
I
L
Y
G
L
A
V
A
A
V
F
-
L
V
L
A
A
L
Y
E
S
W
S
I
P
L
A
V
I
L
V
I
P
L
G
L
I
G
A
A
A
G
V
T
G
R
N
L
F
E
G
L
LGSVPS
F
A
N
D
I
Y
F
Q
V
G
F
-
V
T
V
M
G
L
S
A
K
N
A
I
L
I
I
E
F
A
K
D
L
Q
A
-
Q
-----------
G
K
S
A
V
E
A
A
L
E
A
A
R
L
R
F
R
P
I
I
M
T
S
F
A
F
I
L
G
V
V
P
L
Y
I
---
A
AGA
S
S
---
A
S
Q
R
A
I
G
T
T
V
F
W
G
M
L
V
G
T
L
L
---
S
V
F
L
V
P
L
F
Y
-----
V
V
V
R
K
F
------
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
51.17
14%
-198
* C2 *
3NE5
-
CUSA_ECOLI
A:
[836-1043]
-----------------------------------------------------------------------------------------------------------------------------------------------
V
V
H
D
L
Q
K
A
I
A
E
KV
Q
---
L
K
P
G
T
S
V
A
F
----
S
G
Q
F
E
L
L
E
RA-
N
--
H
K
L
K
L
M
V
P
M
T
L
M
I
I
F
-
V
L
L
Y
L
A
F
R
R
V
G
E
A
L
L
I
I
S
S
V
P
F
A
L
V
G
G
I
W
L
L
W
W
M
G
F
-----------
H
L
S
V
A
T
G
T
G
F
I
A
L
-
A
G
V
A
A
E
F
G
V
V
M
L
M
Y
L
R
H
A
I
E
-
A
VPSLNNPQTFS
E
Q
K
L
D
E
A
L
Y
H
G
A
V
L
R
V
R
P
K
A
M
T
V
A
V
I
I
A
G
L
L
P
I
L
W
---
G
---
T
G
AGS
E
V
M
S
R
I
A
A
P
M
I
G
G
M
I
T
A
P
L
L
---
S
L
F
I
I
P
A
A
Y
-----
K
L
M
W
L
H
------
R
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
50.16
16%
-188
- C2 -
4DX5
5
ACRB_ECOLI
A:
[852-1037]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
P
T
G
V
G
Y
D
W
----
T
G
M
S
Y
Q
E
R
---
L
SG
N
Q
A
P
S
L
Y
A
I
S
L
I
V
V
F
-
L
C
L
A
A
L
Y
E
S
W
S
I
P
F
S
V
M
L
V
V
P
L
G
V
I
G
A
L
L
A
A
T
F
R
G
L
-----------
T
N
D
V
Y
F
Q
V
G
L
L
T
T
-
I
G
L
S
A
K
N
A
I
L
I
V
E
F
A
K
D
L
M
D
K
E
-----------
G
K
G
L
I
E
A
T
L
D
A
V
R
M
R
L
R
P
I
L
M
T
S
L
A
F
I
L
G
V
M
P
L
V
I
---
S
---
T
G
AG
S
G
A
Q
N
A
V
G
T
G
V
M
G
G
M
V
T
A
T
V
L
---
A
I
F
F
V
P
V
F
F
-----
V
V
V
R
R
R
------
F
S
R
K
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
48.25
18%
-177
- C1 -
4Y0L
10
A:
[2-78]
------------------------------------------------------------------------
V
Q
V
L
V
R
F
D
A
G
-
G
A
S
A
P
E
H
S
Q
T
I
A
A
I
R
H
R
I
A
Q
A
P
N
V
V
S
V
A
P
P
----
R
F
A
D
D
N
G
S
A
L
L
S
A
V
L
--------A
R
D
T
I
T
W
M
R
T
Q
L
P
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
47.62
19%
-187
- C2 -
3AQP
-
SECDF_THET8
A:
[252-438]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
L
K
V
A
E
I
R
A
I
G
P
T
L
G
Q
D
A
I
Q
A
G
I
R
S
A
L
I
G
T
L
A
I
F
L
L
I
F
A
Y
Y
G
-
P
H
L
G
L
V
A
S
L
G
L
L
Y
T
S
A
L
I
L
G
L
L
S
---------------
G
L
G
A
T
-----
L
T
L
P
G
----
I
A
G
L
V
L
T
-------
L
G
A
A
V
D
G
N
V
L
S
F
E
R
I
K
E
E
L
R
-
A
--
G
K
K
L
R
Q
A
I
P
E
G
F
R
H
S
T
L
T
I
M
D
V
N
I
A
H
L
L
A
A
A
A
L
Y
Q
Y
---
A
---
T
---
G
P
V
R
G
F
A
V
I
L
A
I
G
V
V
A
-
S
V
F
S
N
L
V
F
S
R
H
L
L
E
R
L
A
D
R
G
E
I
R
-------------------------------------------------
25
HHSearch
45.14
13%
-185
- C2 -
3W9I
1
MEXB_PSEAE
A:
[851-1030]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
P
K
G
V
G
Y
S
W
----
T
G
L
S
Y
E
E
R
---
L
SG-
Q
A
P
A
L
Y
A
L
S
L
L
V
V
F
-
L
C
L
A
A
L
Y
E
S
W
S
I
P
F
S
V
M
L
V
V
P
L
G
V
I
G
A
L
L
A
T
S
M
R
G
L
-----------
S
N
D
V
F
F
Q
V
G
L
L
T
T
-
I
G
L
S
A
K
N
A
I
L
I
V
E
F
A
K
E
L
H
E
-
Q
-----------
G
K
G
I
V
E
A
A
I
E
A
C
R
M
R
L
R
P
I
V
M
T
S
L
A
F
I
L
G
V
V
P
L
A
I
---
S
---
T
G
A
G
S
G
S
Q
H
A
I
G
T
G
V
I
G
G
M
V
T
A
T
V
L
---
A
I
F
W
V
P
L
F
Y
-----
V
A
V
S
T
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
43.46
20%
-174
- C1 -
4Y0L
9
A:
[17-76]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
----
H
S
----
Q
--------------------------------------------
T
I
A
A
I
R
H
R
--------------------------------------------------
I
A
Q
A
--
P
N
-
V
V
S
V
A
P
--------
P
----------
R
-----------------------------------------
F
------------------
A
-------------------------------
D
---------------------
D
----------
N
G
S
A
L
L
S
A
V
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
D
T
I
T
W
---
M
R
T
Q
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
41.52
14%
-208
- C2 -
4K0J
-
?
A:
[840-1018]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
I
Q
V
A
W
----
G
G
Q
F
E
N
Q
Q
R
A
-
Q
--
A
R
L
A
V
I
L
P
M
V
L
A
L
M
F
-
V
L
L
F
-------
Q
P
A
L
I
L
M
A
V
P
L
A
T
L
G
G
L
V
A
L
H
L
R
G
M
-----------
T
L
N
V
S
S
A
V
G
F
I
A
L
-
F
G
V
A
V
L
N
A
I
I
M
I
A
N
L
----------------------
K
E
A
V
V
R
G
A
G
E
R
M
R
P
V
L
M
T
A
T
V
A
A
L
G
L
I
P
A
A
L
---
A
HGL
G
S
---
D
V
Q
R
P
L
A
T
V
V
V
G
G
L
I
T
A
T
A
L
---
T
L
V
L
L
P
A
L
Y
-----
Y
L
I
E
T
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
40.96
32%
-190
- C1 -
1PV8
1
HEM2_HUMAN
A:
[43-148]
--------------------------------------------------------------------------------------------------------------------------------
D
I
Q
P
I
T
S
L
P
G
V
A
-
R
Y
G
V
K
R
L
E
E
M
L
R
P
--
L
---
V
E
E
G
L
R
C
V
L
I
F
G
V
P
-------------------
E
E
S
P
A
I
E
A
I
-
H
L
L
R
K
T
F
P
N
L
L
V
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
40.50
32%
-164
- C1 -
1RHZ
-
SECY_METJA
A:
[129-228]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
G
A
F
G
I
L
T
P
L
L
A
F
L
V
I
I
Q
I
A
F
G
S
I
I
L
I
Y
L
D
E
I
V
S
K
Y
G
I
G
S
G
I
G
L
----------------
F
I
A
A
G
V
S
Q
T
I
--
F
V
G
-
A
L
G
P
E
G
Y
L
W
K
F
L
N
S
---
L
I
-
Q
-----------
G
V
P
N
I
E
Y
I
A
P
I
I
G
T
---
I
I
V
F
--
L
M
V
V
Y
A
E
C
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
40.05
32%
-152
- C1 -
1RH5
-
SECY_METJA
A:
[129-240]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
G
A
F
G
I
L
T
P
L
L
A
F
L
V
I
I
Q
I
A
F
G
S
I
I
L
I
Y
L
D
E
I
V
S
K
Y
G
I
G
S
G
I
G
L
----------------
F
I
A
A
G
V
S
Q
T
I
--
F
V
G
-
A
L
G
P
E
G
Y
L
W
K
F
L
N
S
---
L
I
-
Q
-----------
G
V
P
N
I
E
Y
I
A
P
I
I
G
T
---
I
I
V
F
--
L
M
V
V
Y
A
E
C
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
39.78
32%
-165
- C1 -
3DKN
-
SECY_METJA
A:
[128-227]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
G
A
F
G
I
L
T
P
L
L
A
F
L
V
I
I
Q
I
A
F
G
S
I
I
L
I
Y
L
D
E
I
V
S
K
Y
G
I
G
S
G
I
G
L
----------------
F
I
A
A
G
V
S
Q
T
I
--
F
V
G
-
A
L
G
P
E
G
Y
L
W
K
F
L
N
S
---
L
I
-
Q
-----------
G
V
P
N
I
E
Y
I
A
P
I
I
G
T
---
I
I
V
F
--
L
M
V
V
Y
A
E
C
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
39.53
32%
-166
- C1 -
3BO0
-
SECY_METJA
A:
[128-227]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
G
A
F
G
I
L
T
P
L
L
A
F
L
V
I
I
Q
I
A
F
G
S
I
I
L
I
Y
L
D
E
I
V
S
K
Y
G
I
G
S
G
I
G
L
----------------
F
I
A
A
G
V
S
Q
T
I
--
F
V
G
-
A
L
G
P
E
G
Y
L
W
K
F
L
N
S
---
L
I
-
Q
-----------
G
V
P
N
I
E
Y
I
A
P
I
I
G
T
---
I
I
V
F
--
L
M
V
V
Y
A
E
C
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------