@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu05870: (2016-06-09 )
MTHPLFLEPVFKERLWGGTKLRDAFGYAIPSQKTGECWAVSAHAHGSSSVKNGPLAGKTLDQVWKDHPEIFGFPDGKVFPLLVKLLDANMDLSVQVHPDDDYAKLHENGDLGKTECWYIIDCKDDAELILGHHASTKEEFKQRIESGDWNGLLRRIKIKPGDFFYVPSGTLHALCKGTLVLEIQQNSDTTYRVYDYDRCNDQGQKRTLHIEKAMEVITIPHIDKVHTPEVKEVGNAEIIVYVQSDYFSVYKWKISGRAAFPSYQTYLLGSVLSGSGRIINNGIQYECNAGSHFILPAHFGEFTIEGTCEFMISHP
Atome Classification :
(20 SA)
-------------------------------------------.........10.---------------.....-.----.-20....-----....-----30....-.....40...-----.....50-........60----...-.--....---------70----...------------..------...----.80.......-.90....--....100..-------....-----------------.110-----------------.......120--------------------------------------.-------------------.......130..-.-..----------------------..140...-------------------------------------.-----------------------------------.--------..---.--------------------150------------------------..--------.....-.160.......170---....----...-180-...--.------.----..190..--.....200......-.210----..----------.......220......-.230...----.--.....240..---.---..----------------------------....250.....---.--.260-....-.....----270.......280---.......290........300.....-..310...----------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------------------------------MTHPLF
L
E
P
V
F
K
---------------
E
RLWG-G----T-
K
L
R
D
AF-----GYAI-----P-SQKT-G
E
C
W
A
V
S
A
HA-----HGSSSVK-NGPLAG
K
T
L
D
----
Q
V
W
-
K
--DHP
E
---------
I
-----FGF------------PD------G
K
V
----
F
P
L
L
V
K
L
LDA-NM
D
L
S
V
Q
--VHPDD
D
Y
A
K
-------
L
HEN-----------------GDLG-----------------K
T
E
C
W
Y
I
I
D---------------------------------------C-------------------KDD
A
E
L
I
LGHHA-S-
T
K
----------------------
E
E
F
K
-
Q
R
I-------------------------------------E-----------------------------------S--------G
D
---
W
--------------------
N
G
-------------------------
L
L
--------
R
R
I
KI-KPG
D
F
F
Y
VPS
G
T
L
H
---
A
LCK----G
T
L
-
V
L
E
-
I
QQ--N------S----D
T
T
Y
R
V
Y
--
D
YDRCNDQGQ
K
R
T
L
-
H
I
------
E
K----------A
M
E
V
I
TIPHIDKVHT
P
-
E
V
--
K
EV----G--N
A
E
I
I
V
--
Y
V---Q---SD----------------------------
Y
F
S
V
Y
K
W
K
ISGR---A--AF---P
S
Y
Q
-
T
Y
L
L
G
----
S
V
LSGS
G
R
I
INN
G
---
I
Q
Y
E
CNAG-
S
H
F
I
L
PAHFG
E
F
T
I
E
G
T
-
C
E
F
M
ISHP----------------------------
19
HHSearch
78.67
57%
-98
- C2 -
1QWR
5
MANA3_BACSU
A:
[5-319]
-------------------------------------------
T
Q
S
P
I
F
L
T
P
V
F
K
---------------
E
K
I
W
G
-
G
----
T
-
A
L
R
D
R
F
-----
G
Y
S
I
-----
P
-
S
E
S
T
-
G
E
C
W
A
I
S
A
H
P
-----
K
G
P
S
T
V
A
-
N
G
P
Y
K
G
K
T
L
I
----
E
L
W
-
E
--
E
H
R
E
---------
V
-----
F
G
G
------------
V
E
------
G
D
R
----
F
P
L
L
T
K
L
L
D
V
-
K
E
D
T
S
I
K
--
V
H
P
D
D
Y
Y
A
G
-------
E
N
E
E
-----------------
G
E
L
G
-----------------
K
T
E
C
W
Y
I
I
D
---------------------------------------
C
-------------------
K
E
N
A
E
I
I
Y
G
H
T
A
-
R
-
S
K
----------------------
T
E
L
V
-
T
M
I
-------------------------------------
N
-----------------------------------
S
--------
G
D
---
W
--------------------
E
G
-------------------------
L
L
--------
R
R
I
K
I
-
K
P
G
D
F
Y
Y
V
P
S
G
T
L
H
---
A
L
C
K
----
G
A
L
-
V
L
E
-
T
Q
Q
--
N
------
S
----
D
A
T
Y
R
V
Y
--
D
Y
D
R
L
D
S
N
G
S
P
R
E
L
-
H
F
------
A
K
----------
A
V
N
A
A
T
V
P
H
V
D
G
Y
I
D
E
-
S
T
--
E
S
R
----
K
--
G
I
T
I
K
T
--
F
V
---
Q
---
G
E
----------------------------
Y
F
S
V
Y
K
W
D
I
N
G
E
---
A
--
E
M
---
A
Q
D
E
-
S
F
L
I
C
----
S
V
I
E
G
S
G
L
L
K
Y
E
D
---
K
T
C
P
L
K
K
G
-
D
H
F
I
L
P
A
Q
M
P
D
F
T
I
K
G
T
-
C
T
L
I
V
S
H
I
----------------------------
1
PsiBlast_PDB
76.31
57%
-99
- C2 -
1QWR
5
MANA3_BACSU
A:
[8-318]
----------------------------------------------
P
I
F
L
T
P
V
F
K
---------------
E
K
I
W
G
-
G
----
T
-
A
L
R
D
R
F
-----
G
Y
S
I
-----
P
-
S
E
S
T
-
G
E
C
W
A
I
S
A
H
P
-----
K
G
P
S
T
V
A
-
N
G
P
Y
K
G
K
T
L
I
----
E
L
W
-
E
--
E
H
R
E
---------
V
-----
F
G
G
------------
V
E
------
G
D
R
----
F
P
L
L
T
K
L
L
D
V
-
K
E
D
T
S
I
K
--
V
H
P
D
D
Y
Y
A
G
-------
E
N
E
E
-----------------
G
E
L
G
-----------------
K
T
E
C
W
Y
I
I
D
---------------------------------------
C
-------------------
K
E
N
A
E
I
I
Y
G
H
T
A
-
R
-
S
K
----------------------
T
E
L
V
-
T
M
I
-------------------------------------
N
-----------------------------------
S
--------
G
D
---
W
--------------------
E
G
-------------------------
L
L
--------
R
R
I
K
I
-
K
P
G
D
F
Y
Y
V
P
S
G
T
L
H
---
A
L
C
K
----
G
A
L
-
V
L
E
-
T
Q
Q
--
N
------
S
----
D
A
T
Y
R
V
Y
--
D
Y
D
R
L
D
S
N
G
S
P
R
E
L
-
H
F
------
A
K
----------
A
V
N
A
A
T
V
P
H
V
D
G
Y
I
D
E
-
S
T
--
E
S
R
----
K
--
G
I
T
I
K
T
--
F
V
---
Q
---
G
E
----------------------------
Y
F
S
V
Y
K
W
D
I
N
G
E
---
A
--
E
M
---
A
Q
D
E
-
S
F
L
I
C
----
S
V
I
E
G
S
G
L
L
K
Y
E
D
---
K
T
C
P
L
K
K
G
-
D
H
F
I
L
P
A
Q
M
P
D
F
T
I
K
G
T
-
C
T
L
I
V
S
H
-----------------------------
21
HHSearch
49.36
22%
-97
- C2 -
1ZX5
10
?
A:
[5-297]
-------------------------------------------
P
S
F
I
F
Q
A
Q
E
N
L
V
---------------
E
R
P
W
G
-
G
----
E
-
W
I
A
L
L
K
-----
G
F
-------
R
-
Q
S
G
I
-
G
E
S
W
E
F
S
A
H
T
-----
S
R
P
S
T
V
L
V
K
G
--
Q
Q
L
S
M
I
----
E
L
F
-
S
--
K
H
R
D
E
--------
L
-----
L
G
R
------------
A
A
EK----
F
S
K
----
F
P
I
L
V
R
L
I
D
A
-
A
S
P
T
Q
V
H
--
V
H
P
S
D
K
A
A
E
-------
S
L
G
E
-----------------
A
E
G
G
-----------------
V
E
S
A
W
L
V
F
N
-------------------------------------------------------------
K
G
K
A
Y
A
G
F
K
E
D
V
-
K
I
----------------------
E
E
L
E
-
E
K
L
-------------------------------------
K
-----------------------------------
E
--------
E
D
FD-
F
--------------------
K
T
-------------------------
L
L
--------
N
T
F
E
T
-
T
P
Y
D
T
F
V
I
R
P
G
I
P
H
---
A
-
G
E
----
G
L
R
-
V
L
E
-
V
S
S
--
N
------
S
----
T
L
A
Y
F
F
N
EN
D
W
E
K
-------------------------------
V
K
K
V
L
N
T
K
K
V
E
E
F
E
V
-----------------
K
G
K
K
G
--
M
A
---
E
---
T
E
----------------------------
N
F
G
L
E
V
V
D
V
T
G
T
---
A
--
E
I
---
K
T
G
G
-
V
M
N
I
L
----
Y
A
A
E
G
Y
F
I
L
R
G
K
E
----
T
A
D
L
H
R
G
-
Y
S
C
L
V
P
A
S
T
D
S
F
T
V
E
S
E
R
G
K
I
V
R
I
Y
-----------------------------
20
HHSearch
47.19
20%
-86
- C2 -
2WFP
16
MANA_SALTY
A:
[1-391]
-------------------------------------------
M
A
S
M
Q
K
L
I
N
S
V
Q
---------------
N
Y
A
W
G
-
S
----
K
T
A
L
T
E
L
Y
-----
G
I
A
N
-----
P
Q
Q
Q
P
M
-
A
E
L
W
M
-
G
A
H
P
-----
K
S
S
S
R
I
T
------
T
V
S
L
R
----
D
A
I
-
E
--
K
N
K
T
A--------
M
-----
L
G
E
------------
A
V
A
N
R---
F
G
E
----
L
P
F
L
F
K
V
L
C
A
-
A
Q
P
L
S
I
Q
--
V
H
P
N
K
R
N
S
E
-------
I
G
F
A
K
E
N
A
A
GIPMDAAERNYK
D
P
N
H
-----------------
K
P
E
L
V
F
A
L
T
---------------------------------------
P
F
L
A
M
N
A
FRE
F
S
D
I
V
S
L
L
Q
P
V
A
G
A
H
S
A
I
A
H
F
L
Q
V
P
N
A
E
R
L
S
Q
L
F
A
S
L
L
N
MQG
E
E
K
S
R
A
L
A
V
L
K
-
A
A
L
-------------------------------------
N
-----------------------------------
S
--------
Q
Q
GE
P
W
Q
T
I
R
V
I
S
E
Y
YPDDSGLF
S
--
P
L
-------------------------
L
L
--------
N
V
V
K
L
-
N
P
G
E
A
M
F
L
F
A
E
T
P
H
---
A
Y
L
Q
----
G
V
--
A
L
E
-
V
M
A
--
N
------
S
----
D
N
V
L
R
A
--------
G
L
T
--
P
K
Y
I
-
D
I
------
P
E
----------
L
V
A
N
V
K
F
E
P
K
P
A
G
E
L
L
-
T
A
--
P
V
K
----
S
--
G
A
E
L
D
F
PI
P
V
---
D
---
D
F
----------------------------
A
F
S
L
H
D
L
A
L
Q
E
T
-------
S
---
I
G
Q
H
-
S
A
A
I
L
----
F
C
V
E
G
E
A
V
L
R
K
D
E
---
Q
R
L
V
L
K
P
G
-
E
S
A
F
I
G
A
D
E
S
P
V
N
A
S
G
T
-
G
R
L
A
R
V
Y
-----------------------------
43
Fugue
46.29
18%
-107
- C2 -
3H1W
7
MANA_SALTY
A:
[1-393]
--------------------------------------------
A
S
M
Q
K
L
I
N
S
V
Q
---------------
N
Y
A
W
G
S
K
----
T
-
A
L
T
E
L
Y
-----
G
I
A
N
-----
P
-
Q
Q
Q
P
M
A
E
L
W
M
-
G
A
H
P
-----
K
S
S
S
R
I
T
-
G
E
---
T
V
S
L
R
----
D
A
I
-
E
--
K
N
K
T
---------
A
-----
M
L
G
------------
E
A
------
V
A
N
R
FGE
L
P
F
L
F
K
V
L
C
A
-
A
Q
P
L
S
I
Q
--
V
H
P
N
K
R
N
S
E
-------
I
G
F
A
-----------------
K
E
N
A
A
GIPMDAAERNYKDP
N
H
K
P
E
L
V
F
A
L
T
P
F
L
A
M
N
A
FRE
F
S
D
I
V
S
L
L
Q
PVAGAH
S
A
I
A
H
F
L
Q
V
PN
A
E
R
L
-------------------
S
Q
L
F
A
S
L
L
N
M
Q
G
-
E
-
E
K
----------------------
S
R
A
L
-
A
V
L
-------------------------------------
K
-----------------------------------
A
--------
A
L
---
N
--------------------
S
Q
QGE
P
W
Q
T
I
R
V
I
S
E
Y
YPDDSGLF
S
P
L
L
L
--------
N
V
V
K
L
-
N
P
G
E
A
M
F
L
F
A
E
T
P
H
---
A
Y
L
Q
----
G
-
V
-
A
L
E
-
V
M
A
--
N
------
S
----
D
N
V
L
R
A
G
--
L
T
P
K
Y
I
D
---------
I
------
P
E
----------
L
V
A
N
V
K
F
E
P
K
P
A
G
E
L
L
-
T
A
--
P
V
K
----
S
--
G
A
E
L
D
F
--
P
I
---
P
---
V
D
----------------------------
D
F
A
F
S
L
H
D
L
A
L
Q
---
E
--
T
S
---
I
G
Q
H
-
S
A
A
I
L
----
F
C
V
E
G
E
A
V
L
R
K
D
E
---
Q
R
L
V
L
K
P
G
-
E
S
A
F
I
G
A
D
E
S
P
V
N
A
S
G
T
-
G
R
L
A
R
V
Y
N
KL--------------------------
22
HHSearch
42.60
17%
-79
* C2 *
1PMI
1
MPI_CANAL
A:
[2-421]
-------------------------------------------
S
E
K
L
F
R
I
Q
C
G
Y
Q
---------------
N
Y
D
W
G
-
K
IGSS
S
-
A
V
A
Q
F
V
-----
H
N
S
D
PSITI
D
E
T
K
P
Y
-
A
E
L
W
M
G
-
T
H
P
-----
S
V
P
S
K
A
I
-
D
L
--
N
N
Q
T
L
R
----
D
L
V
-
T
--
A
K
P
Q
E--------
Y
-----
L
G
E
------------
S
I
I
T
K
F
GS
S
K
E
----
L
P
F
L
F
K
V
L
S
I
-
E
K
V
L
S
I
Q
--
A
H
P
D
K
K
L
G
A
Q
L
H
A
A
DP
K
N
Y
P
-----------------
D
D
N
H
-----------------
K
P
E
M
A
I
A
V
T
-------------------------------------------------------------
D
F
E
G
F
C
G
F
K
P
L
D
-
Q
L
----------------------
A
K
T
L
-
A
T
V
P
E
L
N
E
I
I
G
Q
E
L
V
D
E
F
I
S
G
IKLPAEVGS
Q
D
D
V
N
N
R
K
L
L
Q
K
V
F
G
K
L
M
N
TD
D
D
V
I
K
Q
Q
T
A
K
L
L
E
R
T
D
R
E
P
Q
V
F
K
D
I
D
--------
S
R
---
L
P
E
L
I
Q
R
L
N
K
Q
FPNDIGLFCG
C
L
-------------------------
L
L
--------
N
H
V
G
L
-
N
K
G
E
A
M
F
L
Q
A
K
D
P
H
---
A
Y
I
S
----
G
-
D
-
I
I
E
-
C
M
A
--
A
------
S
----
D
N
V
V
R
A
--------
G
F
T
P
K
--
F
K
-
D
V
------
K
N
----------
L
V
E
M
L
T
Y
S
Y
E
S
V
E
K
Q
K
M
P
L
Q
E
F
P
R
SKGD
A
--
V
K
S
V
L
Y
--
D
P
---
P
---
I
A
----------------------------
E
F
S
V
L
Q
T
I
F
D
K
S
K
G
G
K
Q
-
V
I
---
E
G
L
N
-
G
P
S
I
V
----
I
A
T
N
G
K
G
T
I
Q
I
T
G
DDS
T
K
Q
K
I
D
T
G
-
Y
V
F
F
V
A
P
G
S
-
S
I
E
L
T
---------------------------------------
15
PsiBlast_PDB
40.08
45%
-365
- C2 -
2H0V
3
QDOI_BACSU
A:
[258-277]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
E
I
Q
L
-
N
P
G
D
F
L
H
V
P
A
N
T
V
H
---
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
39.57
45%
-337
- C2 -
1Y3T
1
QDOI_BACSU
A:
[257-276]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
E
I
Q
L
-
N
P
G
D
F
L
H
V
P
A
N
T
V
H
---
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
35.34
25%
-68
- C2 -
1ZX5
10
?
A:
[17-259]
----------------------------------------------------------------------
E
R
P
W
G
-
G
----
E
-
W
I
A
L
L
K
-----
G
F
R
--------
Q
S
G
I
-
G
E
S
W
E
F
S
A
H
T
-----
S
R
P
S
T
V
L
-
V
K
G
Q
Q
L
S
M
I
E
----
L
F
S
-
K
--
H
R
D
E
---------
L
-----
L
G
R
------------
A
A
------
E
K
F
SK--
F
P
I
L
V
R
L
I
D
A
-
A
S
P
T
Q
V
H
--
V
H
P
S
D
K
A
A
E
-------
S
L
G
E
-----------------
A
E
G
G
-----------------
V
E
S
A
W
L
V
F
N
K
G
K
A
Y
A
G
--------------------------------
F
-------------------
K
E
D
V
K
I
E
E
L
E
E
K
-
L
-
K
E
----------------------
E
D
F
----------------------------------------------------------------------------------------
D
---
F
--------------------
K
T
-------------------------
L
L
--------
N
T
F
E
T
-
T
P
Y
D
T
F
V
I
R
P
G
I
P
H
---
A
-
G
E
----
G
L
R
-
V
L
E
-
V
S
S
--
N
------
S
----
T
L
A
Y
F
F
N
--
E
N
D
W
E
K
V
K
K
V
L
N
T
K
-
K
V
------
E
E
FEVKGKKG
M
A
E
T
E
N
F
G
L
E
V
V
D
V
T
G
T
A
-
E
I
--
K
-
T
----
G
--
G
V
M
N
I
L
--
Y
A
---
A
---
E
G
----------------------------
Y
F
------------------------------------------------------------------------------------------------------------------
45
Fugue
34.43
21%
-87
* C3 *
4ZOX
-
SQT1_YEAST
A:
[53-431]
-MSNNSL
T
Y
F
D
KHTDSVF
A
I
G
H
H
PNLP
L
V
C
T
G
GGDN
L
A
H
L
W
T
S
H
S
Q
P
----
P
K
F
A
---------------
G
T
L
T
G
Y
G
----
E
-
S
V
I
S
C
S
F
T
SEG
G
F
L
V
-----
T
-
A
D
M
S
-
G
K
V
L
V
H
M
G
Q
------
K
G
G
A
Q
W
K
-
L
A
S
Q
M
Q
E
V
E
E
----
I
V
W
L
K
--
T
H
P
T
---------
I
AR
T
F
A
F
G
A
------------
T
D
------
G
S
V
----
W
C
Y
Q
I
N
E
Q
D
G
-
S
L
E
Q
L
M
S
G
F
V
H
Q
Q
D
C
S
M
G
-------
E
F
I
N
-----------------
T
D
K
G
-----------------
E
N
T
-
L
E
L
V
T
---------------------------------------
C
-------------------
S
L
D
S
T
I
V
A
W
N
C
F
-
T
-
G
Q
----------------------
Q
L
F
K
I
T
Q
A
-------------------------------------
E
-----------------------------------
I
--------
K
G
---
L
--------------------
E
A
-------------------------
P
W
--------
I
S
L
S
L
-
A
P
E
T
L
T
K
G
N
S
G
V
V
A
---
C
G
S
N
----
N
G
L
-
L
A
V
-
I
N
----------------------------
C
N
N
G
G
A
I
L
H
L
-
S
T
V
I
E
L
K
P
E
Q
----------
D
E
L
D
A
S
I
E
S
I
S
W
S
S
K
F
-
S
L
--
M
A
I
----
G
L
V
C
G
E
I
L
L
--
Y
D
---
T
---
S
A
----------------------------
W
R
V
R
H
K
F
V
L
E
D
S
---
V
--
T
K
---
L
M
F
D
N
D
D
L
F
A
----
S
C
I
N
G
------
K
V
---
Y
Q
F
N
A
R
T
G
Q
E
K
F
V
C
V
G
H
N
-----
M
G
V
-
L
D
F
I
L
L
H
P
VANTG
T
E
Q
K
R
K
V
I
T
A
G
DEG
V
S
L
V
F
E
V
P
N
31
HHSearch
30.49
12%
-145
- C2 -
1RC6
-
ALLE_ECOLI
A:
[1080-1239]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
-----------------
I
E
T
F
L
Y
V
I
S
---------------------------------------
G
---------------------
N
I
T
A
K
A
E
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
T
F
A
L
-
S
E
G
G
Y
L
Y
C
P
P
G
S
L
M
---
T
F
V
N
AQA
E
D
S
Q
-
I
F
L
-
Y
K
R
--
R
------
Y
----
V
P
---
V
---
E
----
G
Y
A
P
W
L
V
S
G
-
N
A
------
S
E
----------
L
---------
E
R
I
-------------------
V
I
L
L
D
--
F
L
PKE
L
---
G
F
----------------------------
D
M
N
M
H
I
L
S
F
A
P
G
---
A
--
S
H
G
Y
I
E
T
H
V
-
Q
E
H
G
A
----
Y
I
L
S
G
Q
G
V
Y
N
L
D
N
---
N
W
I
P
V
K
K
G
-
D
Y
I
F
M
G
A
Y
S
L
--------------------------------------------
37
HHSearch
29.87
14%
-172
- C2 -
4H7L
1
?
A:
[66-127]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
Q
E
I
Y
V
V
L
D
---------------------------------------
H
-------------------
A
A
H
A
T
I
E
L
N
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
S
Y
P
L
-
T
K
L
L
A
I
S
I
P
P
L
V
R
H
---
R
I
V
G
----
E
A
T
-
I
I
N
-
I
V
S
--
P
------
P
FDPA
D
E
W
F
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
28.04
14%
-132
- C2 -
3RNS
1
?
A:
[56-212]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
-----------------
G
N
R
Y
Y
Y
C
F
N
---------------------------------------
G
---------------------
N
G
E
I
F
I
E
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
K
K
T
I
-
S
N
G
D
F
L
E
I
T
A
N
H
N
Y
---
S
I
E
A
RD--
N
L
K
-
L
I
E
-
I
G
E
--
K
------
I
----------------------
S
--
A
F
-
N
L
------
A
E
----------
V
V
---
E
Y
Q
E
-------------------
G
--
K
I
V
S
K
N
--
L
V
---
A
---
K
P
----------------------------
N
L
V
M
T
I
M
S
F
W
K
G
---
E
S
L
D
P
---
H
K
A
P
-
G
D
A
L
V
----
T
V
L
D
G
E
G
K
Y
Y
V
D
G
---
K
P
F
I
V
K
K
G
-
E
S
A
V
L
P
A
N
I
P
-
H
A
V
E
---------------------------------------
46
Fugue
26.59
14%
-74
- C2 -
2YU2
1
KDM2A_HUMAN
A:
[34-451]
-----GKRTFD
L
E
E
K
L
HTNKYNANF
V
T
F
M
E
GKDFN
V
E
Y
I
Q
R
GG
L
R
D
P
L
I
F
K
N
S
D
G
LG
I
K
M
P
DPDFT
V
N
D
V
K
M
C
V
G
-
S
----
R
-
R
M
V
D
V
M
-----
D
V
N
T
-----
Q
-
K
G
I
E
-
M
T
M
A
Q
W
T
R
Y
Y
-----
E
T
P
E
E
E
R
-
E
K
L
Y
N
V
I
S
L
E
FSHT
R
L
E
-
N
MV
Q
R
P
S
---------
T
-----
V
D
F
------------
I
D
WV----
D
N
M
----
W
P
R
H
L
K
M
Q
Y
P
-
K
V
Q
K
Y
C
L
--
M
S
V
R
G
C
Y
T
D
-------
F
H
-------------------
V
D
F
G
-----------------
G
T
S
V
W
Y
H
I
H
---------------------------------------
Q
-------------------
G
G
K
V
F
W
L
I
P
P
T
A
-
H
-
N
L
----------------------
E
L
Y
E
-
N
W
L
-------------------------------------
L
-----------------------------------
S
GSQGDIF
L
G
D
---
R
--------------------
V
S
-------------------------
D
C
--------
Q
R
I
E
L
-
K
Q
G
Y
T
F
V
I
P
S
G
W
I
H
---
A
V
Y
T
----
P
T
D
-
T
L
V
-
F
G
G
--
N
F
L
H
SFN
I
----
P
M
Q
L
K
I
Y
--
N
I
E
D
R
T
R
V
P
N
K
F
R
Y
P
F
Y
------
Y
E
----------
M
C
W
Y
V
L
E
R
Y
V
Y
C
I
T
N
R
-
S
H
--
L
T
K
----
E
--
F
Q
K
E
S
L
--
S
M
---
D
---
L
E
----------------------------
Q
V
H
L
T
H
F
E
L
E
G
L
---
R
--
C
L
---
V
D
K
L
-
E
S
L
-
P
----
L
H
K
K
C
V
P
T
G
I
E
D
E
---
D
A
L
I
A
D
V
K
-
I
L
L
E
E
L
A
N
S
D
P
K
L
A
L
-
T
-
G
V
P
I
V
Q
W
P
----------------------------
30
HHSearch
26.51
16%
-117
- C2 -
1SQ4
2
?
A:
[89-247]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
-----------------
A
E
A
V
L
F
V
V
E
---------------------------------------
G
---------------------
E
L
S
L
T
L
Q
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
V
H
A
M
-
Q
P
G
G
Y
A
F
I
P
P
G
A
D
Y
---
K
V
R
N
TTG
Q
H
T
R
-
F
H
W
-
I
R
K
--
H
------
Y
----
Q
K
V
-----------
D
G
V
P
L
P
E
-----------------------
A
-
F
V
T
N
E
Q
D
I
Q
P
L
V
M
P
--
D
--
T
E
G
----
R
--
W
S
T
T
R
F
--
V
D
---
M
SDM
R
H
----------------------------
D
M
H
V
N
I
V
N
F
E
P
G
---
G
V
I
P
F
A--
E
T
H
V
-
M
E
H
G
L
----
Y
V
L
E
G
K
A
V
Y
R
L
N
Q
---
D
W
V
E
V
E
A
G
-
D
F
M
W
L
R
A
F
C
P
--------------------------------------------
38
HHSearch
25.93
12%
-170
- C2 -
4ZU5
1
?
A:
[45-125]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
T
R
G
Y
H
--
S
H
K
-------------------------------------
K
-----------------
L
H
Q
V
L
I
C
L
N
---------------------------------------
G
---------------------
S
V
K
I
R
L
K
I
P
D
------------------------------------------------------------------------------------------------------------------------------------------------
E
-------------------------
E
---------
K
I
I
E
L
N
D
P
S
V
G
L
Y
I
G
P
L
V
W
R
---
E
M
F
D
FTE-
G
C
V
-
L
L
V
-
L
A
S
--
E
------
Y
YDE-
T
D
Y
I
R
N
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
Fugue
25.66
17%
-162
- C1 -
4XGC
1
ORC5_DROME
E:
[1-458]
M
E
A
I
C
S
S
L
E
PLFPCR
E
A
A
I
E
T
L
G
E
L
IGDSSETYPS
A
I
Y
L
F
G
H
S
G
T
G
K
T
A
L
T
R
A
F
L
---------------
K
E
C
G
K
-
R
----
Q
-
N
V
R
T
A
H
-----
L
N
A
I
-----
E
-
C
Y
T
T
-
K
I
M
L
E
I
L
L
D
S
L
A
PDQ
G
D
A
L
K
V
D
-
N
M
L
D
F
V
E
Q
L
R
----
R
Q
A
-
A
--
T
R
V
E
---------
D
-----
Q
G
F
L
I
A
V
D
NAERLRD
M
D
------
A
N
V
----
L
P
V
L
L
R
L
Q
E
L
T
N
L
N
L
C
V
I
--
L
L
S
Q
L
P
F
E
K
-------
F
Y
N
K
-----------------
T
G
L
S
-----------------
E
I
V
C
L
H
L
A
Q
---------------------------------------
Y
N------------------
K
A
E
T
Q
R
I
L
G
S
---
D
-
F
Q
----------------------
Q
V
R
N
-
Q
L
L
-------------------------------------
E
-----------------------------------
Q
--------
K
K
---
R
--------------------
L
E
-------------------------
I
C
--------
Q
E
-
A
V
-
T
E
D
F
Y
N
N
Y
L
N
L
F
L
S
---
V
F
Y
K
----
A
C
R
D
V
P
E
-
L
Q
L
--
T
------
A
----
R
K
C
L
S
T
Y
--
L
E
P
V
L
D
G
T
S
R
L
W
-
R
-
H
I
------
A
G
----------
P
L
R
S
A
L
T
Q
I
Y
M
R
I
E
S
L
-
E
L
--
P
Y
Y
----
A
--
K
F
L
L
I
A
--
A
F
---
L
---
A
S
H
N
AAKQDKRLFSTTL
G
P
K
S
F
S
I
D
R
L
L
A
I
F
Y
A
I
L
E
E
K
V
G
L
T
---
C
--
N
L
---
L
S
Q
I
-
S
T
L
V
H
L
NL
L
S
F
V
S
G
E
Q
N
I
M
E
G
S
---
A
R
L
Q
C
T
I
G
-
L
E
F
V
L
--
Q
I
G
K
V
V
G
F
N
V
-
R
Q
Y
L
C
D
------------------------------
9
PsiBlast_PDB
24.24
27%
-82
- C2 -
4QX8
3
KDM2A_MOUSE
A:
[179-258]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
G
-----------------
G
T
S
V
W
Y
H
I
H
---------------------------------------
Q
-------------------
G
G
K
V
F
W
L
I
P
P
T
A
-
H
-
N
L
----------------------
E
L
Y
E
-
N
W
L
-------------------------------------
L
-----------------------------------
S
--------
G
K
---
Q
--------------------
G
D
-------------------------
I
F
L
G
D
R
V
S
D
C
Q
R
I
E
L
-
K
Q
G
Y
T
F
V
I
P
S
G
W
I
H
---
A
V
Y
T
----
P
T
D
-
T
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
24.15
27%
-90
- C2 -
4QXC
3
KDM2A_MOUSE
A:
[179-258]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
G
-----------------
G
T
S
V
W
Y
H
I
H
---------------------------------------
Q
-------------------
G
G
K
V
F
W
L
I
P
P
T
A
-
H
-
N
L
----------------------
E
L
Y
E
-
N
W
L
-------------------------------------
L
-----------------------------------
S
--------
G
K
---
Q
--------------------
G
D
-------------------------
I
F
L
G
D
R
V
S
D
C
Q
R
I
E
L
-
K
Q
G
Y
T
F
V
I
P
S
G
W
I
H
---
A
V
Y
T
----
P
T
D
-
T
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
Fugue
23.60
15%
-40
- C2 -
2Y0O
4
DLYKI_BACSU
A:
[2-172]
-----------------------------------------------------------------------------------------------------------------
G
I
T
K
E
E
V
-----
N
S
Y
Y
Q
K
A
-
G
I
V
L
T
D
E
E
V
D
----
Q
I
Q
-
L
M
-
D
Y
G
L
GKERK
V
G
L
Q
L
-----
F
V
Y
------------
V
N
------
T
D
R
----
Y
C
S
K
E
L
V
L
F
P
-
G
Q
T
C
P
E
H
--
R
H
P
--------------
P
V
D
-----------------
G
Q
E
G
-----------------
K
Q
E
T
F
R
C
R
Y
------------------------------------------------------------
G
K
V
Y
L
Y
V
E
G
E
K
-
T
-
P
L
----------------------
P
K
V
L
-
P
P
Q
-------------------------------------
E
-----------------------------------
D
--------
R
E
---
H
--------------------
Y
T
-------------------------
V
W
--------
H
E
I
E
L
-
E
P
G
G
Q
Y
T
I
P
P
N
T
K
H
W
F
Q
A
G
E
E
----
G
A
V
-
V
T
E
M
S
S
T
ST
D
------
K
----
H
D
I
F
T
D
P
--
R
I
L
E
H
H
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------