@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu06110: (2016-06-09 )
MDKSSKFFFEDQKYNKERIVRVLGGNLALLKSKGILYEDSSGDLIFNYVGVISNGRNVIFILPKYCNRHLDEHSKRTLFNKLLKIFKKYSGLNKSRESDYFVSELDSDEVSDFMIADYLLNDFSLNGYYQKKFTEYEIDGEGIIDWSKTVNEITPVFSKGVPYYFSTYNEVVQKDEYHLIVKIHKWALSKYFNDFGVILGFTGLEFDKSCDGMKILDYADFFGSVINKEIVNTYVDRDVKLLKALKTAIDREENQFSKRPTLSLYGTKYFHRVWEEVCKTVFSHVNEYVKKISRPNWINFTDIEVNKEKKTLEPDIIKAFEYRSKEYFLILDAKYYNINFDGKKLEGNPGVEDITKQLLYDKALEKLSRGKTKHNAFLFPSSNSTNTFKVFGSVDFDFLDIAAVTLVYISAEQVYNLYLENKTFSTDDLFKFVSEINKSKKRHSVITSTLYGNMFLFTKRLSDKN
Atome Classification :
(20 SA)
--------------------------------------------.........10.....-----..----------.20.....--------------------...----------30-........40..----------..-------------....----50........60........70........-------80..-..-....90.---...--..--..-------------100---.......110.-----......120.......130.......140.......150-....-.-----..160-..--------..------....170....-----..----.180.......190.-.......200---......----.-.--.210..----------.-----------...-.220-.....--..-.230-----.....--..-240.......----250.......260..-....-----------------------..270..--------..----...--280....-----...290....-..-------------------.-----------300......---.310.....-----..---------320---------------------------------.........330-----......--.340------.....--------...--------.350-.....------------------------------..360----........370........380----------.........390.......400...-----------....-410-.......--------.420.......430.......440----.......450.......460...---------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------------------------MDKSS
K
F
F
FEDQKY
N
K
-----
E
R
----------
I
V
R
V
LGG
N
--------------------
L
A
L
----------
L
K-SK
G
I
L
Y
EDSSG
D
----------
L
I
-------------
F
N
Y
V
----
G
VISNG
R
N
V
I
F
I
L
P
K
Y
C
N
R
H
L
D
E
H
S
K
R
T
L
F
-------
N
K
L
L
-
K
I
-
F
K
K
YSGL---NKS--RE--SD-------------Y
F
V
---
S
ELD
S
D
E
V
S
D
F
-----
M
I
A
D
Y
L
L
NDFSLN
G
Y
Y
Q
K
K
F
T
E
Y
EIDG
E
G
I
I
D
W
S
K
T
V
N
E
-
I
T
P
V
-F-----SKGV--
P
Y
--------
Y
F
------
S
T
Y
N
E
V
VQKDE-----
Y
H
----
L
I
V
K
I
H
K
W
A
L
S
K
Y
-
F
-
N
D
F
G
V
I
L
G-----FTGLEF----D-K--SCDG
M
K
----------
I
-----------
L
D
Y
-
A
D
F
--
F
G
S
V
I
--
N
K
-
E
I
V
N
-----
T
Y
V
D
R
--
D
V
-
K
L
L
K
A
L
K
T
A
I----DR
E
E
N
QFSKRP-
T
L
S
-
L
Y
G
T
-----------------------
K
Y
F
H
R
V
W
--------
E
E
----
V
C
K
--
T
V
F
S
H
V
N
-----
E
Y
V
K
KISRPN-
W
I
-------------------
N
-----------
F
T
D
I
E
VNKE---KKTL
E
P
D
I
I
-----
K
A
---------
F
-----------------------------------EYRS
K
E
Y
F
L
I
L
D
-----
A
K
Y
Y
N
I
--NF--------DGKKL--------EGN--------P
G
V
E
-
D
I
T
K
Q
------------------------------
L
L
Y
D
-----
K
A
L
E
K
L
SRGK-TKH
N
A
F
L
F
P------------SSNST
N
T
F
K
V
F
GSVD
F
D
F
L
D
I
A
A
V
T
-----------
L
V
Y
I-
S
A
--
E
Q
V
Y
N
L
Y
--------LENKTF
S
T
D
D
L
F
K
F
V
S
E
I
N
K
S
K
K
R
----
H
S
V
I
T
S
T
LYG
N
M
F
L
F
T
KRLSDKN---------------------------------------------------------------------------------------------------------------------
32
Fugue
67.73
16%
-73
* C7 *
4IA6
21
?
A:
[1-591]
--------------------------------------------
M
Y
Y
S
N
G
N
Y
E
A
F
A
D
P
K
K
PAGVD
K
K
----------
S
A
Y
I
I
G
S
G
--------------------
L
A
G
----------
L
S
-
T
A
V
F
L
V
R
D
--
A
Q
----------
M
K
-------------
G
E
N
I
----
H
I
L
E
E
L
P
V
A
G
F
V
V
R
--
G
G
R
E
M
E
N
H
-----
F
-------
E
C
L
W
-
D
M
-
Y
R
S
I
P
S
L
EVP
G
A
S
--
Y
L
--
D
E
-------------
Y
Y
W
---
L
D
K
E
D
P
N
S
S
N
C
-----
R
L
I
Y
N
R
G
D
R
L
P
S
D
G
Q
Y
G
L
G
K
C
A
N
E
I
V
K
L
I
M
T
P
E
K
E
I
E
G
Q
T
I
E
E
F
-
F
-----
S
D
E
F
F
K
T
N
--------
F
W
------
T
Y
W
S
T
M
F
A
F
E
K
-----
W
H
----
S
L
A
E
M
R
R
Y
A
M
R
-
F
-
I
-
H
H
I
D
G
L
P
D
-----
F
T
A
L
K
F
N
KYN
Q
-
Y
--
E
S
M
V
K
P
----------
L
-----------
L
A
Y
-
L
K
D
--
H
G
V
Q
F
E
Y
D
C
-
H
V
K
N
-----
V
E
V
D
H
E
G
D
S
-
K
I
A
K
K
I
V
M
T
Q
----
N
G
K
D
K
E
I
D
L
T
H
-
N
D
I
-
V
F
V
T
NGSITES
S
T
Y
G
D
QNTPAPITNAK
G
D
S
W
K
L
W
--------
E
N
----
L
A
K
Q
D
P
A
F
G
H
P
D
-----
V
F
C
E
N
L
P
E
R
S
-
W
F
-------------------
V
-----------
S
A
T
A
T
L
E
N
K
---
K
--
L
A
P
Y
F
E
-----
R
L
---------
T
KRSLYDGKVNTGGIITIVDSNWE
L
S
F
T
I
H
RQPHFK
S
Q
N
P
D
Q
I
V
V
W
I
Y
-----
A
L
Y
S
D
T
EG
N
Y
--------
I
K
K
R
I
--------
V
D
C
--------
T
G
-
K
-
E
I
A
E
E
------------------------------
L
L
Y
H
L
GVPE
S
Q
I
S
E
L
A
S
E
E
N
M
N
T
V
P
V
Y
M
P
YITSYFMPR---
R
D
G
D
R
P
D
V
V
P
E
G
S
I
N
L
A
F
I
G
N
F
A
E
S
PTRDTVFT
T
E
Y
S
V
R
T
-
A
M
--
E
A
V
Y
T
L
L
NVDRGVPE
V
F
D
S
I
Y
D
I
R
Q
L
L
R
A
M
Y
Y
M
S
D
K
K
K
L
----
A
D
Q
D
M
P
L
P
E
K
L
A
V
K
T
G
M
R
K
I
K
K
T
W
V
E
E
L
L
K
E
A
NLV---------------------------------------------------------------------------------------------------------
33
Fugue
65.48
13%
-61
* C10 *
4WL5
-
?
A:
[1-604]
--------------------------------------------
M
A
K
K
V
N
W
Y
V
S
C
S
P
R
S
P
-----
E
K
----------
I
Q
P
E
L
K
V
L
A
N
F
EGSYWKGVKGY
K
A
Q
E
A
F
A
K
E
----------
L
A
-
A
L
P
Q
F
L
G
T
T
Y
K
K
EAAFS
T
R
D
R
V
A
P
-------------
M
K
T
Y
----
G
F
V
F
V
D
E
E
G
Y
L
R
I
T
E
A
G
K
M
L
A
N
N
R
R
P
K
D
V
F
-------
L
K
Q
L
-
V
K
-
W
Q
Y
P
S
F
Q
---
H
K
G
--
K
E
--
Y
P
EEEWSIN
P
L
V
F
V
L
S
L
L
---
K
K
V
G
G
L
S
K
L
D
I
-----
A
M
F
C
L
T
A
T
N
N
N
Q
V
D
E
I
A
E
E
I
M
Q
F
R
N
E
R
E
K
I
K
G
Q
N
K
K
L
E
F
-
T
E
N
Y
-
F
-----
F
K
R
F
--
E
K
--------
I
Y
GNVS
H
K
S
K
I
E
T
K
M
R
N
A
R
-----
D
V
----
A
D
A
T
T
R
Y
F
R
Y
T
G
L
-
F
-
V
A
R
G
N
Q
L
V
-----
L
N
P
E
K
S
----
D
-
L
--
I
D
E
I
I
S
S
S
K
V
V
KNYTR
V
-----------
E
E
F
-
H
E
Y
--
Y
G
N
P
S
--
L
P
-
Q
F
S
F
-----
E
T
K
E
Q
--
L
L
-
D
L
A
H
R
I
R
D
E
N
----
T
R
L
A
E
Q
L
V
E
H
F
-
P
N
V
-
K
V
E
I
-----------------------
Q
V
L
E
D
I
Y
N
SLNKKVD
V
E
----
T
L
K
--
D
V
I
Y
H
A
K
-----
E
L
Q
L
E
L
K
K
K
K
-
L
Q
-------------------
A
D
F
NDP
R
Q
L
E
E
V
I
D
L
L
E
V
Y
H
E
---
K
K
N
V
I
E
E
K
I
-----
K
A
R
FIAN
K
N
T
V
F
-----------------------------------
E
W
L
T
W
N
G
F
I
I
L
G
NALEY
K
N
N
F
V
I
--
D
E
--------
E
L
Q
P
V
--------
T
H
A
--------
A
G
N
Q
P
A
M
E
I
I
Y
ED
F
I
V
L
G
E
V
T
TSKGATQFKME
S
E
P
V
T
R
H
Y
L
N
K
K
-----
K
E
L
E
K
Q
G
V
E
K
-
E
L
Y
C
L
F
I
A
P
------------
E
I
N
K
N
T
F
E
E
F
M
K
Y
N
I
V
Q
N
T
R
I
I
P
L
S
-----------
L
K
Q
F
-
N
M
L
L
M
V
Q
K
K
L
I
--------
E
K
G
R
R
L
S
S
Y
D
I
K
N
L
M
V
S
L
Y
R
T
T
I
E
CERK
Y
T
Q
I
K
A
G
L
E
E
T
L
N
N
W
V
V
D
K
E
V
R
F
---------------------------------------------------------------------------------------------------------------------
34
Fugue
53.82
15%
-74
* C9 *
4JW1
2
?
A:
[18-625]
------------------------------------VRFAG
F
Y
K
D
N
D
G
G
K
F
F
I
K
K
P
G
D
P
R
-----
E
L
----------
F
T
E
L
F
A
G
L
--------------------
L
L
K
----------
E
F
M
K
R
G
L
I
D
E
S
Y
F
P
S
----------
L
I
-------------
C
A
D
V
----
I
Q
F
E
D
K
-
S
Y
G
L
I
Q
P
L
V
S
F
D
E
L
H
K
V
I
G
Q
N
K
Y
-------
F
G
L
S
M
A
L
M
F
S
L
L
L
G
A
---
H
S
V
--
H
S
--
G
N
-------------
I
V
V
---
L
N
G
E
E
K
E
K
S
K
---------
Q
F
G
R
I
D
W
G
D
R
Y
F
A
H
P
N
N
N
D
N
L
Y
A
K
D
Y
F
L
N
Y
K
K
-
I
N
G
-
L
F
P
A
M
A
-----
E
K
A
R
--
Q
L
Q
S
K
LN
P
E
L
L
V
------
K
I
V
T
S
A
L
K
N
I
P
-----
A
D
----
L
I
D
E
K
T
K
I
Q
L
A
A
Y
M
C
M
D
S
F
K
E
A
-----------
T
F
----
G
-
T
--
E
G
N
C
K
D
----------
F
-----------
A
I
A
M
A
T
L
--
L
E
N
R
L
--
G
K
I
A
V
L
K
-----
L
K
P
L
T
--
L
L
M
T
S
S
T
S
F
S
E
T
I
----
N
Q
W
A
D
I
L
K
T
T
D
M
E
K
F
-
S
F
D
S
-----------------------
N
P
I
N
--
L
--------
L
E
----
L
V
K
--
Q
F
N
L
Y
V
D
-----
E
L
A
I
T
C
E
A
N
N
V
W
L
FALYDNSGGEAIHGHAFVP
Y
-----------
Y
K
E
S
I
V
L
R
R
---
L
F
T
V
D
P
N
T
F
N
L
S
R
F
A
A
---------
F
-----------------------------------
E
G
P
C
Q
L
Y
C
K
E
H
K
DS
A
W
-
V
K
I
Q
T
L
--
L
T
--------
L
G
N
G
I
I
N
T
L
K
I
I
K
Q
A
Q
--------
A
F
G
I
-
D
E
A
V
T
------------------------------
E
N
L
K
-----
A
L
K
E
Q
F
I
A
F
Q
-
L
A
E
A
D
I
K
E
P
------------
N
K
E
S
E
F
----
F
Y
P
I
D
E
K
A
L
A
K
-------------------M
N
G
--
Y
Q
L
A
T
I
C
--------
L
E
E
--
L
N
S
P
K
P
S
P
L
I
E
R
I
L
S
N
K
K
F
----
W
K
R
I
N
S
A
F
E
S
G
V
F
K
G
R
T
D
D
P
A
G
K
I
A
K
I
R
E
W
H
Q
L
L
Q
IS-------------------------------------------------------------------------------------------------------
40
Fugue
53.32
14%
-97
- C3 -
5FRP
-
?
A:
[3-691]
KGAVTKLK
F
N
S
P
IISTSD
Q
L
I
S
T
N
E
L
L
D
R
L
K
A
L
H
E
E
L
A
S
LDQDN
T
D
L
T
G
L
D
K
Y
R
D
A
L
V
S
R
-----
K
L
L
K
HKD
V
G
I
R
A
F
T
A
C
C
L
S
D
--------------------
I
L
R
----------
L
Y
-
A
P
D
A
P
Y
T
D
A
Q
L
T
----------
D
I
-------------
F
K
L
V
L
S
Q
F
E
Q
L
G
D
Q
E
N
G
Y
H
I
Q
Q
T
Y
L
I
T
K
L
L
E
Y
R
S
I
V
L
L
ADLPS
S
N
N
L
L
I
-
E
L
-
F
H
I
F
Y
D
P
---
N
K
S
F
P
A
R
--
L
F
-------------
N
V
I
---
G
G
I
L
G
E
V
I
S
E
F
DSVP
L
E
V
L
R
L
I
F
N
K
F
L
T
Y
N
P
N
E
I
P
E
G
L
N
V
T
S
D
C
G
Y
E
V
S
L
I
L
C
D
T
-
Y
S
N
R
-
M
-----
S
R
H
L
--
T
K
--------
Y
Y
------
S
E
I
I
H
E
A
T
N
D
D
NNSR
L
L
T
----
V
V
V
K
L
H
K
L
V
L
R
L
W
-
E
-
T
V
P
E
L
I
N
A
-----
V
I
G
F
I
Y
----
H
-
E
L
S
S
E
N
E
L
F
----------
R
-----------
K
E
A
-
T
K
L
--
I
G
Q
I
L
--
T
S
-
Y
S
D
L
-----
N
F
V
S
T
--
H
S
-
D
T
F
K
A
W
I
S
K
I
ADIS
P
D
V
R
V
E
W
T
E
S
I
-
P
Q
I
-
I
A
T
R
-----------------------
E
D
I
S
K
E
L
--------
N
Q
----
A
L
A
--
K
T
F
I
D
S
D
-----
P
R
V
R
R
T
S
V
M
I
-
F
N
-------------------
K
-----------
V
P
V
T
E
I
W
K
N
ITN
K
A
I
Y
T
S
L
L
H
-----
L
A
---------
R
-----------------------------------
E
K
H
K
E
V
R
E
L
C
I
N
T
M
---
A
K
F
Y
S
N
--
S
L
N
E
I
E
R
T
YQ
N
K
E
I
W
--------
E
I
I
--------
D
T
I
P
-
S
T
L
Y
N
------------------------------
L
Y
Y
I
-----
N
D
L
N
I
N
E
Q
V
D
-
S
V
I
F
E
Y
L
L
P
------------
F
E
P
D
N
D
K
R
V
H
R
L
L
T
V
L
S
H
F
D
K
K
A
F
T
-----------
S
F
F
A
-
F
N
--
A
R
Q
I
K
I
S
--------
F
A
I
S
K
Y
I
D
F
S
K
F
L
N
N
Q
E
-
S
M
S
S
S
Q
----
G
P
I
V
M
N
K
Y
N
Q
T
L
Q
W
L
A
S
G
L
S
D
S
T
K
A
I
D
A
L
E
T
I
K
Q
F
ND
E
R
I
F
Y
L
L
N
A
C
V
TNDIP
F
L
T
F
K
N
C
Y
N
E
L
V
S
K
L
QTPSIMP
R
D
I
A
K
V
I
Q
I
L
L
F
R
A
SPIIYNV
S
N
I
S
V
L
LNLSNNSD
A
K
Q
L
D
L
K
R
R
I
L
D
D
I
S
K
V
NP
T
L
F
K
D
Q
I
R
T
L
K
41
Fugue
47.54
12%
-49
- C5 -
4XE7
-
?
A:
[1-419]
---------------------------------------------------
M
V
E
Q
M
L
S
K
N
-----
M
L
----------
L
G
G
F
D
T
G
N
----------------------------------
I
-
K
A
K
I
S
F
L
N
E
K
G
N
----------
I
E
-------------
S
F
A
I
P
---
T
V
I
A
E
A
P
P
A
K
I
D
L
K
S
A
P
S
K
K
N
D
Y
V
N
E
K
D
E
D
-------
I
E
L
L
-
H
V
-
R
I
I
S
N
S
L
---
D
G
D
--
A
R
--
S
R
-------------
A
W
Y
V
G
A
Y
A
K
D
Q
E
D
R
Q
E
P
-----
T
V
D
E
M
G
K
T
E
D
K
F
S
Q
K
N
K
K
L
H
L
I
P
L
F
T
S
M
A
V
A
A
A
R
I
G
K
E
E
-
V
S
V
P
-
F
-----
S
G
G
M
--
P
----------
I
------
E
D
Y
K
L
R
G
E
E
Q
I
-----
L
E
----
M
L
Y
G
E
H
T
V
E
F
L
D
G
T
Y
-
E
G
K
K
I
K
I
T
-----
I
N
D
G
T
M
----
N
V
E
--
G
V
S
S
V
L
----------
A
-----------
I
L
F
-
D
I
V
--
N
G
E
I
V
--
E
V
-
E
G
M
D
AEIG
E
S
Y
A
I
N
--
D
L
-
G
A
G
T
S
D
N
A
F
F
----
E
D
G
E
L
N
K
K
L
S
T
-
N
T
D
-
L
G
T
N
-----------------------
K
Y
I
D
E
I
L
--------
K
N
----
I
K
E
--
R
F
M
E
N
E
I
-----
L
K
S
F
M
T
D
E
I
E
-
S
P
-------------------
F
-----------
K
T
R
E
D
F
I
Q
R
-----
L
V
M
P
E
V
E
-----
K
M
---------
I
-----------------------------------
E
D
D
T
Y
K
P
T
F
-----------------------------
S
V
--------
K
W
G
--------
P
V
K
E
-
N
V
T
D
I
------------------------------
V
--
M
-----
D
G
M
L
K
Y
A
E
D
Q
-
K
A
S
L
M
K
F
W
F
------------
K
T
N
A
D
K
N
I
V
V
G
G
G
V
L
F
----------------------------------
G
Y
--------
A
G
L
R
D
L
K
E
Q
D
G
F
I
L
P
K
N
I
Q
E
S
A
Y
----------
F
T
S
R
S
Y
L
I
A
N
L
L
E
Q
L
N
K
E
---------------------------------------------------------------------------------------------------------------------
39
Fugue
43.44
11%
-38
- C10 -
2EWF
13
?
A:
[7-610]
--------------------------------------------
M
A
K
K
V
N
W
Y
V
S
C
S
P
R
S
P
-----
E
K
----------
I
Q
P
E
L
K
V
L
--------------------
A
N
F
EGSYWKGVKG
Y
K
-
A
Q
E
A
F
A
K
E
L
A
A
L
----------
P
Q
FLGAFS
T
R
D
R
V
A
P
M
K
T
Y
----
G
F
V
F
V
D
E
E
G
Y
L
R
I
T
E
A
G
K
M
L
A
N
N
R
R
P
K
D
V
F
-------
L
K
Q
L
-
V
K
-
W
Q
Y
P
S
F
Q
---
H
K
G
--
K
E
--
Y
P
EEE
W
S
I
N
P
L
V
F
V
L
S
L
L
---
K
K
V
G
G
L
S
K
L
D
I
-----
A
M
F
C
L
T
A
T
N
N
N
Q
V
D
E
I
A
E
E
I
M
Q
F
R
N
E
R
E
K
I
K
G
Q
N
K
K
L
E
F
-
T
E
N
Y
-
F
-----
F
K
R
F
--
E
K
--------
I
Y
------
G
N
V
S
H
K
S
K
I
E
T
-----
K
M
----
R
N
A
R
D
V
A
D
A
T
T
R
Y
-
F
-
R
Y
T
G
L
F
V
A
RGN
Q
L
V
L
N
P
E
K
----
S
-
D
--
L
I
D
E
I
I
----------
S
S
S
K
V
V
KNYTR
V
E
E
F
-
H
E
Y
--
Y
G
N
P
S
--
L
P
-
Q
F
S
F
-----
E
T
K
E
Q
--
L
L
-
D
L
A
H
R
I
R
D
E
N
----
T
R
L
A
E
Q
L
V
E
H
F
-
P
N
V
-
K
V
E
I
-----------------------
Q
V
L
E
D
I
Y
--------
N
S
----
L
N
K
--
K
V
D
V
E
T
L
-----
K
D
V
I
Y
H
A
K
E
L
-
Q
L
-------------------
E
-----------
L
K
K
K
K
L
Q
A
D
F
ND
P
R
Q
L
E
E
V
I
D
-----
L
L
---------
E
-----------------------------------
V
Y
H
E
K
K
N
V
I
E
E
K
-----
I
K
A
R
F
I
--
A
N
--------
K
N
T
V
F
--------
E
W
L
T
W
N
G
F
I
I
L
G
N
A
L
-
E
Y
K
N
N
------------------------------
F
V
I
D
-----
E
E
L
Q
P
V
T
H
A
A
-
G
N
Q
P
D
M
E
I
I
Y
ED
F
I
V
L
G
E
V
T
T
S
K
G
A
T
Q
F
K
M
E
S
E
P
V
T
R
H
Y
L
N
K
K
K
E
L
-----------
E
K
Q
G
-
V
E
--
K
E
L
Y
C
L
F
--------
I
A
P
E
I
-
N
K
N
T
F
E
E
F
M
K
Y
N
I
V
Q
N
T
R
----
I
I
P
L
S
L
K
Q
F
N
M
L
L
M
V
Q
K
K
L
I
E
K
G
R
R
L
S
S
Y
D
I
K
N
L
M
V
S
L
Y
R
T
T
I
E
CERK
Y
T
Q
I
K
A
G
L
E
E
T
L
N
N
W
V
V
D
K
EVRF---------------------------------------------------------------------
38
Fugue
39.90
14%
-59
- C7 -
4A1N
4
EXOG_HUMAN
A:
[19-311]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
A
V
L
E
Q
F
G
F
P
L
T
-------
G
T
E
A
-
R
C
-
Y
T
N
H
A
L
S
---
Y
D
Q
--
A
K
RV
P
R
-------------
W
V
L
---
E
H
I
S
K
S
K
I
M
G
D
-------
A
D
R
K
H
C
K
F
K
P
D
P
N
I
P
P
T
F
S
A
F
N
E
D
Y
V
G
S
-
G
W
S
R
G
H
---
M
A
P
A
-
G
NNKFS
S
K
A
M
--
A
E
--------
T
F
------
Y
L
S
N
I
V
P
Q
D
F
D
-----
N
N
S
G
Y
W
N
R
I
E
M
Y
C
R
E
L
T
E
R
-
F
-
E
D
V
W
V
V
S
G
-----
P
L
T
L
P
Q
----
T
-
R
--
G
-
D
G
K
K
----------
I
-----------
V
S
Y
-
Q
V
I
G
E
D
N
V
A
V
--
P
S
-
H
L
Y
K
-----
V
I
L
A
R
RS
S
V
-
S
T
E
P
L
A
L
G
A
F
----
V
V
P
N
E
A
I
G
F
Q
P
-
Q
L
T
-
E
F
-
Q
-----------------------
V
S
L
Q
D
L
E
--------
K
L
----
S
G
L
--
V
F
F
P
H
L
D
RTSDI
R
N
I
C
S
V
D
T
C
K
-
L
L
-------------------
D
-----------
F
Q
E
F
T
L
Y
L
S
---
T
R
K
I
E
G
S
V
L
-----
R
L
---------
E
-----------------------------------
K
I
M
V
N
L
K
N
E
I
E
P
-----
D
D
Y
F
M
S
--
R
Y
--------
E
K
K
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
38.25
25%
-48
- C8 -
2G62
2
PTPA_HUMAN
A:
[19-144]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
F
------
Q
S
R
N
F
I
I
P
K
K
E
-----
I
H
----
T
V
P
D
M
G
K
W
K
R
S
Q
A
-
Y
-
A
D
Y
---
I
G
-----
F
I
-
L
T
L
----
N
-
E
--
G
V
K
G
K
K
----------
L
T----------
F
E
Y
-
R
----------------
V
S
-----
E
A
I
E
K
--
L
V
-
A
L
L
N
T
L
D
R
W
I
----
D
--
E
T
P
P
V
D
Q
P
---
S
-
R
F
G
N
-----------------------
K
A
Y
-
R
T
W
Y
A
K
L
D
---
E
E
A
E
N
L
V
A
T
--
V
V
P
T
H
L
A
-----
A
A
V
P
E
V
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
36.76
24%
-72
- C- -
4RFQ
-
MET18_HUMAN
A:
[193-286]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
L
G
C
G
S
G
-----
L
L
G
I
T
A
----
F
-
K
--
G
--
G
S
K
----------
E
-----------
I
H
F
-
Q
D
Y
--
N
S
M
V
I
--
D
E
-
V
T
L
P
-----
N
V
V
A
N
--
S
T
---
L
E
D
-----------------
R
K
P
-
K
V
T
Q
L
Y
K
C
-----------------------
R
F
F
S
G
E
W
--------
S
E
----
F
C
K
--
L
V
L
S
S
E
K
-----
L
F
V
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
36.64
23%
-17
- C8 -
1K8G
3
TEBA_STENO
A:
[136-222]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
N
A
N
V
F
Y
S
S
S
W
A
L
F
S
T
D
K
R
S
V
---
T
Q
E
I
N
N
-
Q
D
A
V
-------
S
D
T
T
--
P
F
--------
S
F
------
S
S
K
H
A
T
I
E
K
N
E
-----
I
S
----
I
L
Q
N
L
R
K
W
A
-
N
Q
Y
-
F
-
S
S
Y
S
V
I
S
S
DM---
Y
T
A
L
N
K
----
A
-
Q
--
A
Q
K
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
36.46
25%
-19
- C8 -
2I0Q
2
TEBA_STENO
A:
[136-206]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
N
A
N
V
F
Y
S
S
S
W
A
L
F
S
T
D
K
R
S
V
---
T
Q
E
I
N
N
-
Q
D
A
V
-------
S
D
T
T
--
P
F
--------
S
F
------
S
S
K
H
A
T
I
E
K
N
E
-----
I
S
----
I
L
Q
N
L
R
K
W
A
-
N
Q
Y
-
F
-
S
S
Y
S
V
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
36.07
25%
-30
- C8 -
1PHJ
1
TEBA_STENO
A:
[102-176]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
N
A
N
V
F
Y
S
S
S
W
A
L
F
S
T
D
K
R
S
V
---
T
Q
E
I
N
N
-
Q
D
A
V
-------
S
D
T
T
--
P
F
--------
S
F
------
S
S
K
H
A
T
I
E
K
N
E
-----
I
S
----
I
L
Q
N
L
R
K
W
A
-
N
Q
Y
-
F
-
S
S
Y
S
V
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
36.01
46%
-261
* C8 *
1ECI
-
ECAA_ECTTU
A:
[6-18]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
W
--------
E
T
----
V
C
P
--
T
V
E
P
W
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
35.89
25%
-23
- C8 -
1PH5
1
TEBA_STENO
A:
[101-171]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
N
A
N
V
F
Y
S
S
S
W
A
L
F
S
T
D
K
R
S
V
---
T
Q
E
I
N
N
-
Q
D
A
V
-------
S
D
T
T
--
P
F
--------
S
F
------
S
S
K
H
A
T
I
E
K
N
E
-----
I
S
----
I
L
Q
N
L
R
K
W
A
-
N
Q
Y
-
F
-
S
S
Y
S
V
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
35.66
25%
-25
- C8 -
1KIX
2
TEBA_STENO
A:
[136-216]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
N
A
N
V
F
Y
S
S
S
W
A
L
F
S
T
D
K
R
S
V
---
T
Q
E
I
N
N
-
Q
-----------
D
T
T
--
P
F
--------
S
F
------
S
S
K
H
A
T
I
E
K
N
E
-----
I
S
----
I
L
Q
N
L
R
K
W
A
-
N
Q
Y
-
F
-
S
S
Y
S
V
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
35.56
25%
-24
- C8 -
1PH1
1
TEBA_STENO
A:
[102-172]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
N
A
N
V
F
Y
S
S
S
W
A
L
F
S
T
D
K
R
S
V
---
T
Q
E
I
N
N
-
Q
D
A
V
-------
S
D
T
T
--
P
F
--------
S
F
------
S
S
K
H
A
T
I
E
K
N
E
-----
I
S
----
I
L
Q
N
L
R
K
W
A
-
N
Q
Y
-
F
-
S
S
Y
S
V
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
35.53
25%
-8
- C8 -
1OTC
-
TEBA_STENO
A:
[136-206]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
N
A
N
V
F
Y
S
S
S
W
A
L
F
S
T
D
K
R
S
V
---
T
Q
E
I
N
N
-
Q
D
A
V
-------
S
D
T
T
--
P
F
--------
S
F
------
S
S
K
H
A
T
I
E
K
N
E
-----
I
S
----
I
L
Q
N
L
R
K
W
A
-
N
Q
Y
-
F
-
S
S
Y
S
V
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
35.32
25%
-10
- C8 -
1PH3
1
TEBA_STENO
A:
[101-171]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
N
A
N
V
F
Y
S
S
S
W
A
L
F
S
T
D
K
R
S
V
---
T
Q
E
I
N
N
-
Q
D
A
V
-------
S
D
T
T
--
P
F
--------
S
F
------
S
S
K
H
A
T
I
E
K
N
E
-----
I
S
----
I
L
Q
N
L
R
K
W
A
-
N
Q
Y
-
F
-
S
S
Y
S
V
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
35.32
25%
-21
- C8 -
1PH2
1
TEBA_STENO
A:
[101-171]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
N
A
N
V
F
Y
S
S
S
W
A
L
F
S
T
D
K
R
S
V
---
T
Q
E
I
N
N
-
Q
D
A
V
-------
S
D
T
T
--
P
F
--------
S
F
------
S
S
K
H
A
T
I
E
K
N
E
-----
I
S
----
I
L
Q
N
L
R
K
W
A
-
N
Q
Y
-
F
-
S
S
Y
S
V
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
35.25
25%
-5
- C8 -
1PH8
1
TEBA_STENO
A:
[101-171]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
N
A
N
V
F
Y
S
S
S
W
A
L
F
S
T
D
K
R
S
V
---
T
Q
E
I
N
N
-
Q
D
A
V
-------
S
D
T
T
--
P
F
--------
S
F
------
S
S
K
H
A
T
I
E
K
N
E
-----
I
S
----
I
L
Q
N
L
R
K
W
A
-
N
Q
Y
-
F
-
S
S
Y
S
V
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------