@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu06740: (2016-06-10 )
MYNEGVTSPSQLARKKNATDKWHGSSIRKILENPHYTGTLQQCREYRPSVTSKRRRSVNLENQIIIEKSHEPIIPLEDFLIVQEILITRKRRRPQAEVHLFTNTAVCKDCRRSMHFKKNRKGYVCGSYNKHGLKACSDHYVSEIDLTDKVITNLNKIYLKFSKENYFKELSEKALKYKEKIESKIIEINEKLNDKKRDKSNLVISLANGVISKEDYQLAINITNEDISNFETTLHQLSKDLEFQKIEKEIIDFKKSLDKFMKEGTLTPEMLHLLVDEIEVHANGTIEINYRFREPTVPSA
Atome Classification :
(20 SA)
-----------------------------------------------------------.........10........20....--.-...30...-.....40........50.--....----...60....------------....70-...-.....80-----...-----.----.....90.--.--------......100--.-......110---.---.....--.--------..120----------....-----..---...-------------------130.-------......140....-------------------------..-------...150..---------......160.....-----.------------.170-----.....----...-180.......----------------------.190----------.--------......200.-....-----..210.-----.-----.....220......------...230......-------------------------.240--------..-------....-.250---------......-.260-.--.----....------.270.....----------...-----280.......290-------.-.......300-----------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------------------------------------MYNEGVT
S
P
S
Q
L
A
RKKNATDKWH
G
S
--
S
-
I
R
K
I
L
ENP-HYT
G
T
L
Q
Q
C
R
E
YRPSV
T
S
--
K
R
RR----SVNLE
N
Q
I
I
------------
I
EKSHE-PII-
P
L
E
D
F
L
------
I
V
Q
-----
E
----
I
L
I
T
R
KRR--R--------PQ
A
E
V
H
L
F
T--
N
-
T
A
V
C
K
D
C
-----
R
---
R
SMHF--K--------KNR------------K
G
Y
V
-----CG---SYN-------------------KH
G
L
-------
K
A
C
S
DHY--
V
S
EI-------------------------D
L
-------
T
D
K
V
-
I
T
N
---------
L
N
K
I
Y
L
K
FS
K
E
N
Y
F
-----
K
------------
E
L
S
------
E
K
A
L
K
----
Y
K
E
-
K
I
-
E
S
K
I
I
E
I
----------------------
N
E
KL----------N--------DKKRDKS
N
L
V
-
I
S
LA-----NGVISK-----E-----
D
Y
Q
L
A
I
--
N
ITN
E
D
------
I
S
N
F
E
T
T
L
H
Q
L
S
-------------------------KD
L
E
--------
F
Q
-------
K
I
E
K
-
E
I
I
D
---------
F
K
K
S
L
D
-
K
F
M
K
-E--G----TL
T
P
------
E
M
L
-
H
L
L
V
D
----------
E
I
E
-----
V
HAN
G
T
I
E
I
N
Y
R
--------F-REPTVPSA-------------------------
49
Fugue
64.03
19%
-17
- C2 -
4NM6
7
A:
[7-451]
----------------------------------------------------SCRCE
G
P
F
Y
T
H
L
G
A
G
P
N
V
A
A
I
R
E
I
M
E
E
R
F
G
Q
K
--
G
-
K
A
I
R
I
E
R
V
-
I
Y
T
G
K
E
G
K
S
S
Q
G
C
P
I
A
K
W
--
V
V
R
R
----
S
S
S
E
E
K
L
L
C
------------
L
V
R
E
R
A
-
G
H
--
T
C
E
A
A
V
------
I
V
I
-----
L
----
I
L
V
W
E
G
I
P
--
L
--------
S
L
A
D
K
L
Y
S
E
--
L
-
T
E
T
L
R
K
Y
G
T
L
T
N
R
---
R
C
A
L
N
--
E
--------
E
R
T
CACQGLDPET
C
G
A
S
F
S
-----
F
G
C
S
W
S
M
Y
-------------------
Y
N
G
C
-------
K
F
A
R
S
K
I
--
P
R
K
F
-------------------------
K
L
LGDD
P
K
E
E
E
K
L
-
E
S
H
---------
L
Q
N
L
S
T
L
M
A
P
T
--
Y
-----
K
------------
K
L
A
------
P
D
A
Y
N
----
N
Q
I
-
E
Y
-
E
H
R
A
P
E
C
RLGLKEGRPFS
G
V
T
A
C
L
D
F
C
A
H
A
H
R
D
----------
L
--------
H
N
M
Q
N
G
S
T
L
V
-
C
T
L
T
-----
R
E
D
N
R
E
F
G
G
K
P
E
-----
D
E
Q
L
H
V
LP
L
Y
K
V
S
D
------
V
D
E
F
G
S
V
E
A
Q
E
E
-------------------------
K
K
R
S
GA
I
Q
V
L
S
S
F
R
-------
R
K
V
R
-
M
L
A
E
PVKTG
S
D
E
V
W
S
D
S
E
Q
-
S
F
L
D
-
P
--
D
I
G
G
V
A
V
A
P
------
T
H
G
-
S
I
L
I
E
CA--------
K
R
E
-----
L
H
A
T
T
P
L
K
N
P
N
R
----------
N
H
P
T
R
I
S
L
V
F
Y
Q
H
K
SMNEPKHG
L
A
L
W
E
A
K
M
A
E
K
43
Fugue
58.73
17%
-77
- C9 -
4KIS
4
?
A:
[2-328]
--------D
R
M
V
M
G
K
I
K
R
I
E
A
GLPLTTAKGRTFG
Y
D
V
I
DT
K
L
Y
I
N
E
E
E
A
K
Q
L
R
L
I
Y
D
I
F
E
E
E
Q
S
I
T
F
L
Q
K
R
L
K
K
L
G
F
K
-
V
R
T
Y
N
--
R
-
Y
N
N
W
L
T
N
D
-
L
Y
C
G
Y
V
S
Y
------------------------
K
D
K
V
H
------------
V
K
G
I
H
E
-
P
I
I
-
S
E
E
Q
F
Y
------
R
V
Q
-----
E
----
I
F
S
R
M
G
K
N
PN
M
--------
N
K
E
S
A
S
L
L
N
--
N
-
L
V
V
C
S
K
C
-----
G
---
L
G
F
V
H
--
R
--------
R
K
D
------------
T
V
S
-------
R
---
G
K
K
-------------------
Y
H
Y
R
-------
Y
Y
S
C
K
T
Y
--
K
H
T
H
-------------------------
E
L
-------
E
K
----
C
G
---------
N
K
I
W
R
A
D
K
L
E
E
L
I
I
-----
D
------------
R
V
N
------
N
Y
S
F
A
-----
S
R
-
N
I
-
D
K
E
D
E
S
L
----------------------
N
E
K
L
----------
K
--------
I
E
H
A
K
K
K
R
L
F
-
D
L
Y
I
-----
N
G
S
Y
E
V
-----
S
-----
E
L
D
S
M
M
--
N
D
I
D
A
Q
------
I
N
Y
Y
E
A
Q
I
E
A
N
E
-------------------------
E
L
K
K
------------------------------------
N
K
T
V
D
-
F
N
S
L
-
E
--
F
----
R
E
K
Q
------
L
Y
L
-
K
S
L
I
N
----------
K
I
Y
-----
I
D
-
G
E
Q
V
T
I
E
W
L
--------
L
-
E
H
H
H
H
H
H
--------------------------
52
Fugue
51.35
17%
-23
- C5 -
3JWD
10
?
A:
[1-369]
-----------------------------------------------------------
T
E
K
L
W
V
T
V
Y
Y
G
V
P
V
W
K
E
A
T
T
T
L
F
C
A
--
S
D
A
K
A
Y
D
T
E
V
-
H
N
V
W
A
T
H
A
C
V
P
T
D
P
N
P
Q
E
--
V
V
L
V
N
V
T
E
N
F
N
M
W
K
N
D
M
------------
V
E
Q
M
H
E
-
D
I
I
-
S
L
W
D
Q
S
-------------------------
L
K
--
P
--------
C
V
K
L
T
G
G
S
V
--
I
-
T
Q
A
C
P
K
V
-----
S
F
E
P
I
P
I
H
Y
C
A
P
--------
A
G
F
------------
A
I
L
K
-----
C
N
---
N
K
T
-------------------
F
N
G
T
-------
G
P
C
T
N
----
V
S
T
V
-------------------------
Q
C
-------
T
H
G
--
I
R
P
---------
V
V
S
S
Q
L
L
L
N
G
S
L
A
E
-----
E
------------
E
V
V
------
I
R
S
V
N
----
F
T
D
-
N
A
-
K
T
I
I
V
Q
L
----------------------
N
T
S
V
E
I
N
C
T
GA
G
H
C
N
--------
I
A
R
A
K
W
N
N
T
L
-
K
Q
I
A
-----
S
K
L
R
E
Q
-----
F
-----
G
N
N
K
T
I
--
I
F
K
Q
S
S
------
G
G
D
P
E
I
V
T
H
W
F
N
C
GG
E
F
F
Y
C
N
STQLFNSTWFNSTEGS
D
T
I
T
--------
L
P
-------
C
R
I
K
-
Q
I
I
N
---------
M
W
Q
K
V
G
-
K
A
M
Y
-
A
--
P
----
P
I
S
G
Q
I
R
C
S
S
N
I
T
-
G
L
L
L
T
R
D
G
G
NSNNE
S
E
I
F
-----
R
P
G
G
G
D
M
R
D
N
W
R
S
E
L
YK
Y
K
V
V
-
K
I
E
P
L
G
V
A
P
T
K
A---------------------
14
PsiBlast_PDB
48.89
26%
8
- C10 -
4DVZ
-
CAGA_HELPY
A:
[548-717]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
N
--
N
-
L
A
I
T
S
F
V
-----
R
---
R
N
L
E
N
--
K
--------
L
T
A
------------
K
G
L
S
-----
L
Q
---
E
A
N
-------------------
K
-----------
L
I
K
D
F
L
--
S
S
N
K
-------------------------
E
L
-------
A
G
K
A
-
L
-
N
---------
F
N
K
A
V
A
E
A
K
S
T
G
N
Y
-----
D
------------
E
V
K
K
A
Q
K
D
L
E
K
S
L
R
----
K
R
E
-
H
L
-
E
K
---
E
V
----------------------
E
K
K
L
----------
E
--------
S
K
S
G
N
K
------
K
A
Q
-----
A
N
S
Q
K
D
-----
E
-----
I
F
A
L
I
N
--
K
E
A
N
R
D
A
R
A
I
A
Y
T
Q
N
L
K
G
I
K
R
E
L
S
-------------------------
D
K
L
E
-----------------
K
I
S
K
-
D
L
K
D
---------
F
S
K
S
F
D
-
E
F
-------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
47.86
26%
9
- C10 -
4DVY
-
CAGA_HELPY
P:
[548-724]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
N
--
N
-
L
A
I
T
S
F
V
-----
R
---
R
N
L
E
N
--
K
--------
L
T
A
------------
K
G
L
S
-----
L
Q
---
E
A
N
-------------------
K
-----------
L
I
K
D
F
L
--
S
S
N
K
-------------------------
E
L
-------
A
G
K
A
-
L
-
N
---------
F
N
K
A
V
A
E
A
K
S
T
G
N
Y
-----
D
------------
E
V
K
KAQKDL
E
K
S
L
R
----
K
R
E
-
H
L
-
E
K
---
E
V
----------------------
E
K
K
L
----------
E
--------
S
K
S
---
N
K
M
E
-
A
K
A
Q
-----
A
N
S
Q
K
D
-----
E
-----
I
F
A
L
I
N
--
K
E
A
N
R
D
ARAIAY
T
Q
N
L
K
G
I
K
R
E
L
S
-------------------------
D
K
L
E
-----------------
K
I
S
K
-
D
L
K
D
---------
F
S
K
S
F
D
-
E
F
-------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
47.68
26%
-6
- C10 -
3ESK
2
A:
[14-127]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Y
K
-------------------
K
K
D
F
-------
D
T
A
L
K
H
Y
D
K
A
K
E
L
-------------------------
D
P
-------
T
N
M
T
Y
I
T
N
---------
Q
A
A
V
Y
F
E
K
G
D
Y
N
K
C
-----
R
------------
E
L
C
------
E
K
A
-----------------
I
E
V
----------------------
G
R
E
N
----------
R
--------
E
D
Y
R
Q
I
A
K
A
Y
-
A
R
I
G
-----
N
S
Y
F
K
E
-----
E
-----
K
Y
K
D
A
I
--
H
F
Y
N
K
S
------
L
A
E
H
R
T
P
-
D
V
L
K
-------------------------
K
C
Q
Q
--------
A
E
-------
K
I
L
K
-
E
----------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
46.89
26%
-3
- C10 -
1ELR
2
A:
[14-127]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Y
K
-------------------
K
K
D
F
-------
D
T
A
L
K
H
Y
D
K
A
K
E
L
-------------------------
D
P
-------
T
N
M
T
Y
I
T
N
---------
Q
A
A
V
Y
F
E
K
G
D
Y
N
K
C
-----
R
------------
E
L
C
------
E
K
A
-----------------
I
E
V
----------------------
G
R
E
N
----------
R
--------
E
D
Y
R
Q
I
A
K
A
Y
-
A
R
I
G
-----
N
S
Y
F
K
E
-----
E
-----
K
Y
K
D
A
I
--
H
F
Y
N
K
S
------
L
A
E
H
R
T
P
-
D
V
L
K
-------------------------
K
C
Q
Q
--------
A
E
-------
K
I
L
K
-
E
----------------------------------------------------------------------------------------------------------------------------
44
Fugue
46.34
11%
-66
- C7 -
2HVG
8
?
A:
[21-478]
HLKNISPIDGRYKKACGELSAFFS
E
H
A
L
I
K
H
R
I
I
V
E
V
R
W
L
L
F
L
N
E
E
ELFFEKVT
D
H
S
V
E
V
L
N
Q
I
A
T
N
I
T
D
S
D
I
A
R
V
K
A
I
E
H
D
V
K
--
A
-
V
E
Y
F
V
K
E
K
-
L
K
N
S
K
R
E
D
L
L
K
I
K
E
Y
V
H
Y
LC
T
S
E
D
----
I
N
N
V
A
Y
A
T
C
------------
L
K
A
C
L
N
D
V
V
I
-
P
C
L
E
K
I
M
L
K
L
K
D
L
A
V
-----
E
Y
S
H
V
P
L
L
S
R
T
H
G
--
Q
--------
P
A
S
S
T
T
F
G
K
--
E
M
A
N
F
Y
A
R
I
-----
H
---
H
H
V
G
V
--
I
--------
R
R
V
------------
K
V
C
A
K
FNGA
V
G
---
N
F
N
-------------------
A
H
K
V
A
SKDTD
W
V
N
T
I
G
L
F
--
L
K
K
H
FNLTYSIYCTQIQDH
D
Y
I
C
E
L
C
D
G
L
A
R
-------
A
N
G
T
-
L
I
D
---------
L
C
V
D
I
W
L
Y
I
S
N
N
L
L
-----
K
LKSSTMPHKVNP
I
D
F
------
E
N
A
E
G
----
N
L
H
-
I
A
-
N
A
F
F
K
L
F
----------------------
S
S
K
L
----------
P
TSRLQRDL
S
D
S
T
V
L
R
N
I
G
-
S
S
L
A
-----
Y
C
L
I
A
Y
-----
K
-----
S
V
L
K
G
L
--
N
K
I
D
I
D
------
R
R
N
L
E
E
E
L
N
Q
N
W
-------------------------
S
T
L
A
--------
E
P
-------
I
Q
I
V
M
K
R
H
N
---------
Y
V
D
A
Y
E
-
E
L
K
Q
-
F
T
R
G
----
K
V
I
D
------
Q
K
I
M
Q
E
F
I
K
----------
T
K
C
-----
A
F
L
P
Q
D
V
V
D
Q
L
L
--------
E
-
L
T
P
A
T
Y
T
G
Y
A
D
Y
L
A
K
N
V
ERLS------------
51
Fugue
45.11
16%
-40
- C6 -
5A61
6
3PASE_ECOLI
A:
[2-430]
-----------------------A
M
A
Q
E
I
E
L
K
F
I
V
NHSA
V
E
A
L
R
D
H
L
N
T
LGGEHH
D
P
V
Q
L
L
N
I
Y
Y
E
T
P
D
N
W
L
R
G
H
D
M
G
L
R
I
R
G
E
NG
R
-
Y
E
M
T
M
K
V
A
G
R
V
T
G
G
L
H
Q
R
P
E
Y
N
V
A
L
S
E
--
P
T
L
D
----
L
A
Q
L
P
T
E
V
W
PNGELPADLASR
V
Q
P
L
F
S
-
T
D
F
-
Y
R
E
K
W
L
------
V
A
V
DD
S
R
I
E
----
I
A
L
D
Q
G
E
V
--
K
A
GE
F
A
E
P
I
C
E
L
E
L
E
L
L
S
GD
T
-
R
A
V
L
K
L
A
-----
N
---
Q
L
V
S
Q
--
T
G
L
R
Q
G
SLS
K
A
A
------------
R
G
Y
H
-----
L
A
---
Q
G
N
P
A
R
E
I
K
P
T
T
I
L
H
V
A
AKAD
V
E
Q
G
L
-------
E
A
A
F
E
L
A
--
L
A
Q
W
-------------------------
Q
Y
-------
H
E
E
L
-
W
V
R
GNDAA
K
E
Q
V
L
A
A
I
G
L
V
R
H
A
L
M
L
F
GGIVP
R
------------
K
A
S
------
T
H
L
R
D
----
L
L
T
-
Q
C
-
E
A
T
I
A
S
A
----------------------
V
S
A
V
----------
T
--------
A
V
Y
S
T
E
T
A
M
A
K
L
A
L
T
-----
E
W
L
V
S
K
-----
A
WQPFL
D
A
K
A
Q
G
--
K
I
S
D
S
F
------
K
R
F
A
D
I
H
L
S
R
H
A
-------------------------
A
E
L
K
--------
S
V
F
CQPLGD
R
Y
H
D
-
Q
L
P
R
---------
L
T
R
D
I
D
-
S
I
L
L
L
A
--
G
----
Y
Y
D
P
------
V
V
A
-
Q
A
W
L
E
----------
N
W
Q
G
L
R
H
A
I
A
T
G
Q
R
I
E
I
E
H
F
--------
R
-
N
E
A
N
N
Q
E
P
FWL----------------------
3
PsiBlast_PDB
41.91
26%
-122
- C10 -
3P3L
1
?
A:
[203-268]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
I
-
E
K
R
K
V
E
P
----------------------
G
D
D
L
----------
T
--------------
S
D
I
V
-
R
A
F
H
-----
D
G
V
L
-------
D
-----
D
Y
E
L
R
T
--
L
V
A
T
V
L
------
V
A
G
Y
E
T
T
N
H
Q
L
A
-------------------------------------------------
L
-
A
M
Y
D
---------
F
A
Q
H
P
D
-
Q
W
M
K
-----------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
41.36
26%
-112
- C10 -
3P3O
1
?
A:
[213-278]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
I
-
E
K
R
K
V
E
P
----------------------
G
D
D
L
----------
T
--------------
S
D
I
V
-
R
A
F
H
-----
D
G
V
L
-------
D
-----
D
Y
E
L
R
T
--
L
V
A
T
V
L
------
V
A
G
Y
E
T
T
N
H
Q
L
A
-------------------------------------------------
L
-
A
M
Y
D
---------
F
A
Q
H
P
D
-
Q
W
M
K
-----------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
41.22
26%
-120
- C10 -
3P3Z
2
?
A:
[213-278]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
I
-
E
K
R
K
V
E
P
----------------------
G
D
D
L
----------
T
--------------
S
D
I
V
-
R
A
F
H
-----
D
G
V
L
-------
D
-----
D
Y
E
L
R
T
--
L
V
A
T
V
L
------
V
A
G
Y
E
T
T
N
H
Q
L
A
-------------------------------------------------
L
-
A
M
Y
D
---------
F
A
Q
H
P
D
-
Q
W
M
K
-----------------------------------------------------------------------------------------------------
46
Fugue
41.00
12%
-58
- C9 -
2R6O
4
?
A:
[24-281]
------------------------------------------------------------------------------
R
L
T
L
D
T
--
R
-
L
R
Q
A
L
E
R
N
-------
E
L
V
L
H
Y
Q
P
I
V
E
L
--
A
S
G
R
----
I
V
G
G
E
A
L
V
R
------------
W
E
D
P
E
R
-
G
L
V
M
P
S
A
F
I
P
------
A
A
E
-----
D
------------------------
T
G
L
I
V
A
L
S
--
D
-
W
V
L
E
A
C
C
-----
T
---
Q
L
R
A
W
--
Q
--------
Q
Q
---------------------------
G
R
A
-------------------
A
D
D
L
-------
T
L
S
V
N
----
I
S
T
R
-------------------------
Q
F
-------
E
G
E
H
-
L
T
R
---------
A
V
D
R
A
L
A
R
S
--
G
L
R
-----
P
------------
D
C
L
------
E
L
E
I
T
----
E
N
V
M
L
V
M
T
D
E
V
R
T
C
----------------------
L
D
A
L
----------
R
--------
A
R
-----
G
V
R
-
L
A
L
D
-----
D
F
G
T
G
Y
-----
S
-----
S
L
S
Y
L
S
--
Q
L
P
F
H
G
------
L
K
I
D
Q
S
F
V
R
K
I
P
-------------------------
A
H
P
S
--------
E
T
-------
Q
I
V
T
-
T
I
L
A
---------
L
A
R
G
L
G
M
E
V
V
A
-
E
--
G
----
I
E
T
A
------
Q
Q
Y
-
A
F
L
R
D
---------------------
R
G
C
E
F
G
Q
G
N
--------
L
M
S
T
P
Q
A
A
D
A
F
A
S
L
L
D
R
Q
K
A---------------
5
PsiBlast_PDB
40.78
26%
-105
- C10 -
3P3X
2
?
A:
[213-278]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
I
-
E
K
R
K
V
E
P
----------------------
G
D
D
L
----------
T
--------------
S
D
I
V
-
R
A
F
H
-----
D
G
V
L
-------
D
-----
D
Y
E
L
R
T
--
L
V
A
T
V
L
------
V
A
G
Y
E
T
T
N
H
Q
L
A
-------------------------------------------------
L
-
A
M
Y
D
---------
F
A
Q
H
P
D
-
Q
W
M
K
-----------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
39.80
26%
-36
- C10 -
4M44
1
?
B:
[23-115]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
Y
T
----------
S
H
G
-------------------
A
H
G
V
-------
A
V
A
A
D
L
K
--
S
T
Q
--------------------------
E
A
-------
I
N
K
I
-
T
K
N
---------
L
N
S
L
---------------
S
------------
E
L
E
------
V
K
N
L
Q
R
LSG
A
M
D
-
E
L
-
H
N
E
I
L
E
L
----------------------
D
E
K
V
----------
D
--------
D
L
R
A
D
T
I
S
S
Q
-
I
E
L
A
V
L
L
S
N
E
G
I
I
N
S
-----
E
-----
D
E
H
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
38.48
26%
-29
- C10 -
4M40
1
?
B:
[23-115]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
Y
T
----------
S
H
G
-------------------
A
H
G
V
-------
A
V
A
A
D
L
K
--
S
T
Q
--------------------------
E
A
-------
I
N
K
I
-
T
K
N
---------
L
N
S
L
---------------
S
------------
E
L
E
------
V
K
N
L
Q
R
LSG
A
M
D
-
E
L
-
H
N
E
I
L
E
L
----------------------
D
E
K
V
----------
D
--------
D
L
R
A
D
T
I
S
S
Q
-
I
E
L
A
V
L
L
S
N
E
G
I
I
N
S
-----
E
-----
D
E
H
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
38.02
27%
-23
- C10 -
2RFU
1
?
B:
[23-115]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
Y
T
----------
S
H
G
-------------------
A
H
G
V
-------
A
V
A
A
D
-
L
--
K
S
T
Q
-------------------------
E
A
-------
I
N
K
I
-
T
K
N
---------
L
N
S
L
---------------
S
------------
E
L
E
------
V
K
N
L
Q
RLSG
A
M
D
-
E
L
-
H
N
E
I
L
E
L
----------------------
D
E
K
V
----------
D
--------
D
L
R
A
D
T
I
S
S
Q
-
I
E
L
A
V
L
L
S
N
E
G
I
I
N
S
-----
E
-----
D
E
H
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
HHSearch
37.91
19%
-285
* C8 *
4ILO
2
?
A:
[222-236]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
-
L
V
F
C
E
H
C
-----
S
---
R
I
L
Y
W
--
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
37.78
27%
3
- C10 -
4FQM
1
?
B:
[23-115]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
Y
T
----------
S
H
G
-------------------
A
H
G
V
-------
A
V
A
A
D
-
L
--
K
S
T
Q
-------------------------
E
A
-------
I
N
K
I
-
T
K
N
---------
L
N
S
L
---------------
S
------------
E
L
E
------
V
K
N
L
Q
RLSG
A
M
D
-
E
L
-
H
N
E
I
L
E
L
----------------------
D
E
K
V
----------
D
--------
D
L
R
A
D
T
I
S
S
Q
-
I
E
L
A
V
L
L
S
N
E
G
I
I
N
S
-----
E
-----
D
E
H
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
37.52
27%
-26
- C10 -
2RFT
1
?
B:
[23-115]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
Y
T
----------
S
H
G
-------------------
A
H
G
V
-------
A
V
A
A
D
-
L
--
K
S
T
Q
-------------------------
E
A
-------
I
N
K
I
-
T
K
N
---------
L
N
S
L
---------------
S
------------
E
L
E
------
V
K
N
L
Q
RLSG
A
M
D
-
E
L
-
H
N
E
I
L
E
L
----------------------
D
E
K
V
----------
D
--------
D
L
R
A
D
T
I
S
S
Q
-
I
E
L
A
V
L
L
S
N
E
G
I
I
N
S
-----
E
-----
D
E
H
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------