@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu06760: (2016-06-10 )
MALIDLEDKIAEIVNREDHSDFLYELLGVYDVPRATITRLKKGNQNLTKRVGEVHLKNKVWFKEAKKGKLFDALIDIEQQVEYLSAKPRYLLVTDYDGVLAKDTKTLEALDVKFEELPQYFDFFLAWKGIEKVEFEKENPADIKAAERFARIYDVLRKENNIIETNRGLDLFLIRLLFCFFAEDTDIFKRNSFTNLIKTLTEEDGSNLNKLFADLFIVLDKNERDDVPSYLKEFPYVNGQLFTEPHTELEFSAKSRKLIIECGELLNWAKINPDIFGSMIQAVASEESRSYLGMHYTSVPNIMKVIKPLFLDKLNQSFLDAYDDYTKLENLLTRIGKIKFFDPACGSGNFLIITYKELRRMEINIIKRLQELLGEYLYVPSVTLSQFYGIEIEDFAHDVAKLSLWIAEHQMNEELKNEVHNAVRPTLPLHTAGDIRCANAIRVEWTEVCPAQGSEEVYVFGNPPYLGSKKQNKEHKSDMLSIFGKVKNGKMLDYISAWFYFGAKYASTTNAKVAFVSTNSVTQGEQVSILWNELFKFGIQINFAYKSFKWANNAKNNAAVIVVIVGFGPLDTKVNKYLFVDETKKLVSNISPYLTDGENILVSSRTKPISDLPKLHFGNMPNDGGGLLFTITEYTDAINKYPELVPYFKKFIGSVEFINGGLRYCLWLNEAKYEKIKSNPLIQERISISKNHREKSTDKGTNKLALTPWKFRDTHETTNYSIVVPSVSSENRFYIPMGLAGADTILSNLIYVIYDAEIYLLGILMSRMHMTWVKAVAGRLKTDYRYSAGLCYNTFPIPELSTRRKNEIEEAILEILDLREEQGGTLAELYNPSTMPIELKVAHEKLDGIVERAYRQKQFESDEERLEVLLKLYQEMTER
Atome Classification :
(20 SA)
------------------------------------------------.........10.....-----------------------...20......----..30...--.....40.......--.50.-.....----..60.......---.70.......---.80----...-.----....-90.------.......100......-.-110---..-.....120.......130.......140..-------.....150.......160-.....------..170....-------...180......----.190---------------.----------------........200.......210.-.-------------.....220----------.-----------.-----.....230....--------...------------------------------------.240.......250.....-..260.......-----270........---280....---.--..-290-...-.-----....300..---.....310.......320..-------.....330......------.340...----....350......------------.360.....------.-----.370..--------.-.-----..---.380--........390........400...--..---------..410.......420.......430.......440.........450.......460........470..-------....-.480...-----.-...490.....---------..500....---.-------..510.......520.-------.-------.-------.-...530...-----....--540....-....550.......-560--.........570.....-----..-------------------580---...----.--.---.-------------------..-----.590-.----..---.--...---.-600.----...-------...-610.-......620...---------------------------..-....---630.....-..640...--.--------------...650...-....660------.------........670..-----.....680---------.....---....690---.....-.-----.--.700.......710-........720..--.....730...--....740.......750..-.------.----...760.......770-.......780-------------........790.......800.-----------......810.......820.......830.......840.-.....-----.850-------....-....860.....--..----.870.......-------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------------------------------------------MALI
D
L
E
D
K
I
A
E
I
VNR-----------------------E
D
H
S
D
F
L
Y
E
L
L
----
G
VYDV
P
R
--
A
T
I
T
R
L
KKG
N
Q
N
L
T
--
K
R
V
G
-
E
VHLK----N
K
V
W
F
K
EAKKG---
K
L
F
D
A
L
I
D
I
E
---
Q
Q
V
----
E
Y
L-S----AKP
R
-
Y
L
L
------
V
TDYDGVLAKDTK
T
L
E
-
A
-
L
D
V
---
K
F
-
E
E
L
P
Q
Y
F
D
F
F
L
A
WKGI
E
K
V
EFEKENP
A
D
I
K
-------
A
A
E
R
F
A
R
I
Y
D
V
L
RKEN
N
I
-IETNR------
G
L
D
L
F
L
I
R
L
-------
L
F
C
F
FAED
T
D
I
F----KR-----------------
N
----------------
S
F
T
N
L
I
K
T
L
T
EEDGS
N
L
N
K
L
F
A
-
D
-------------
L
F
I
V
LDKN----------E-----------R-----D
D
V
P
S
Y
L
-
K
EFP--------YVN------------------------------------
G
Q
L
FTEPHT
E
L
E
FSAKS
R
K
-
L
I
I
E
C
G
E
LL
N
W
A-----K-I
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P
D
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M
---
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Q
A
V
A
S
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S
Y
--
L
G
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-H-----YTS
V
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N
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M
K
---
V
I
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P
L
F
L
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K
L
N
Q
S
F
L
D
A
Y
D
D
-------
Y
T
K
L
E
N
L
L
T
RIGK
I
------
K
F
FDPAC----GSG
N
F
L
I
I
T
Y
K
E
L
------------
R
R
M
E
I
N
I
I
K
------
R
-----
L
Q
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L
L
G
--------
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-
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-----LY---VPS---V
T
L
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FYGI
E
-
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--
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---------
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AVRPTLPLHTAGD
I
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CA
N
A
--
I
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W
TEVCPAQGS
E
E
V
Y
V
F-GNPPYLGSKKQ
N
K
E
-------
H
K
S
D
-
M
L
S
I
F
G
K-----V-KNG
K
M
L
D
Y
I
S
A
---------
W
F
YFG
A
K
YA---S-------TTN
A
K
V
A
F
V
STNSVTQ-------G-------
E
-------
Q
-
V
S
I
L
W
N
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L
F
-----KF
G
I
--
Q
I
-
N
F
A
Y
-
K
S
F
K
WANNAKN
N
A
A
-
V
----
I
V
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I
VGFGPLDTKV
N
K
Y
-----
L
F
-------------------
V
-----
D
E
T
----
K
--
K
---
L
-------------------
V
S
-----NIS--P----YL---T--DG
E
---
N
-
I
L
VS----SRT-------KPI-SDLP-
K
L
HFGNM--PND---------------------------GG-
G
L
L
F
---
T
I
T
E
Y
T
D
A
-
I
N
KY
P
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L
V
--
P
--------------
Y
F
K
K
F
IGS
V
-
E
F
I
NG--------G------
L
R
Y
C
L
WLN
E
A
K
Y
E
-----
K
IKSNP-----------
L
I
Q
E
R
---
I
S
ISKN----HREKS-T-----D--KGT
N
K
L
ALTP
W
K
F--RDTHETT
N
Y
S
I
V
V
--PSVSSE
N
R
F
Y
I
--PMGLA
G
A
D
T
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N
L
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Y
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A
----
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Y
L
L
G
I
L
M
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R
M
H
M
T
W
-
V
K
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V
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RLK--------------TD
Y
R
YSAGLCYNTFPIPEL
S
T
R
-----------
R
K
N
E
I
E
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A
I
L
E
I
L
D
L
R
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EQGG
T
L
A
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LYNPSTM
P
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K
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A
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-
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K
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-----
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--------
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A
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KQFE
S
-
D
E
E
R
L
--
E
V
----
L
L
K
L
Y
Q
E
M
TER-------------------
44
Fugue
70.69
13%
-65
- C6 -
3S1S
26
?
A:
[6-875]
----------------------------------------------------
L
N
N
C
V
F
S
Y
L
P
S
Y
-----------------------
G
D
D
E
V
S
V
Y
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----
C
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A
A
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K
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--------
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----
Q
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S
----
T
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------
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----
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-----------------
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----------------
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-----
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--------
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I
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F-----------------------------------
N
V
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N
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W
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N
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---
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---
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--
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---------------------------
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---
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K
K
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PR
D
--------------
W
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N
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PIFNEDAT
P
------
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-----
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---
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-
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L
L
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--
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----
V
F
E
R
Y
P
E
G
S
Q
--------------------
21
HHSearch
62.29
12%
-84
- C6 -
3S1S
26
?
A:
[29-870]
-----------------------------------------------------------------------------------------
C
E
A
A
L
N
Q
A
L
----
V
N
T
G
L
D
S
T
Y
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V
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----
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---------------------------
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----
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------------
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N
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----------------------------------------------------
M
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D
T
V
V
F
V
G
R
K
G
S
S
V
E
E
I
E
-----
V
L
D
S
FT---------------
P
LEQVD
L
H
N
----
L
--
K
R
A
L
S
N
SSNE
Q
I
I
Q
P
M
G
M
E
L
R
K
E
K
R
E
E
L
E
N
R
V
T
V
--
G
----
W
R
---
H
IT
S
N
G
R
V
A
E
-
E
W
I
T
N
NLE
S
H
C
-------
I
R
L
V
A
S
D
Y
-
D
L
R
R
G
R
V
GN
K
G
A
---------------------------
S
D
L
L
F
I
N
---
S
K
K
K
L
W
D
L
-
L
-
D
E
S
V
P
R
--
D
--------------
W
L
Y
P
A
L
R
K
V
N
E
I
N
T
P
--------
I
FNEDAT
P
V
R
F
L
C
P
P
N
S
A
Y
Q
DGT
G
E
S
I
I
L
D
K
-----------
I
L
D
V
Y
---
V
D
F
Q
V
Y
K
SKQ
K
K
F
E
K
S
K
-----
E
E
L
K
E
I
L
Y
K
E
S
D
F
Y
S
S
--
E
-------
H
T
V
F
I
--
P
R
A
L
R
---
R
S
A
--
R
A
F
I
N
E
Q
K
V
F
C
S
T
N
A
L
E
V
F
-
G
------
G
N
S
E
E
M
W
L
L
L
S
W
L
S
S
V
F
A
Q
L
Q
-
F
E
A
M
A
K
D
Q
E
--------------
G
E
R
K
L
E
K
K
-
S
I
Q
N
L
Y
I
P
N
L
G
D
I
D
D
V
--------
L
K
Q
D
L
I
E
E
V
R
E
I
H
F
F
D
------------------
L
C
R
P
R
V
-
R
K
L
D
L
-----
L
W
A
--------
K
V
F
W
-
S
G
N
E
M
S
K
T
K
E
A
A
--
E
L
----
L
E
D
L
V
F
E
R
Y
---------------------
45
Fugue
58.69
17%
-87
- C3 -
2EYQ
5
MFD_ECOLI
A:
[5-1150]
PEQYR
Y
T
L
P
V
K
AG
E
Q
R
L
L
GELTGA
A
C
A
T
L
V
A
E
I
A
E
R
HA
G
P
V
V
L
I
A
PD
M
Q
N
A
L
R
L
H
D
E
I
S
Q
F
T
D
Q
M
V
M
N
LADWETLPYDSFSPH
Q
D
I
I
S
S
R
L
S
T
L
Y
Q
L
P
TMQ
R
G
V
L
I
V
P
V
--
N
T
L
M
Q
-
R
V
C
P
H
S
F
L
--
H
G
H
A
-
L
V
M
K
K
----
G
Q
R
L
S
R
D
A
L
R
T
---
Q
L
D
S
A
G
Y
R
H
V
---
D
Q
V
MEHG
E
Y
A
-
T
----
R
G
A
L
-
L
D
L
FPMGSE
L
P
Y
R
L
D
F
F
D
D
E
I
D
S
L
R
-
V
-
F
D
V
DSQ
R
T
-
L
E
E
V
E
A
I
N
L
L
P
A
H
------
E
F
P
T
D
K
A
A
I
E
L
-------
F
R
S
Q
W
R
D
T
F
E
V
K
R
D
P
E
H
I
-
Y
Q
Q
V
S
K
GTLPA
G
I
E
Y
W
Q
P
L
F
F
SEPLPP
L
F
S
Y
F
P
A
N
T
L
L
V
----
N
T
-----------------
G
----------------
D
L
E
T
S
A
E
R
F
Q
A
D
T
L
A
R
F
E
N
R
G
V
-
D
-------------
P
M
R
P
L
L
P
P
----------
Q
-----------
S
LWLR
V
D
E
L
F
S
E
L
-
K
N
W
P
--------
R
V
Q
L
K
TEHLPTKAA
N
A
N
L
GFQKLPDLAVQAQQKAPL
D
A
L
R
K
F
L
E
T
F
D
G
P
V
V
F
S
V
E
S
E
G
-
R
R
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A
L
G
E
L
L
A
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I
-----
K
-
I
A
P
Q
R
I
M
R
L
---
D
E
A
--
S
D
---
R
--
G
R
-
Y
L
--
M
I
G
-
A
AE
H
G
F
V
D
T
V
R
N
L
A
L
---
I
C
E
S
D
L
L
G
E
R
V
A
R
R
R
Q
D
S
R
R
-------
T
I
N
P
D
T
L
I
R
N
L
A
E
L
------
H
I
G
Q
P
V
V
H
LEH
G
V
G
R
Y
A
G
M
T
T
L
E
A
------------
G
G
I
T
G
E
Y
L
M
------------
L
T
Y
A
N
D
--------
A
-
K
-----
L
Y
---
V
P
------
V
S
S
L
H
L
I
S
R
Y
A
G
G
A
E
E
N
A
P
L
H
K
L
GG
D
A
---------
W
S
R
A
R
Q
K
A
A
E
K
V
R
D
V
A
A
E
L
L
D
I
Y
A
Q
R
A
A
K
E
G
F
A
--
F
K
---------
H
D
R
E
Q
Y
Q
L
F
-
C
D
S
F
---
P
F
E
T
T
P
D
-------
Q
A
Q
A
-
I
N
A
V
L
S
D
-----
M
-
C
Q
P
L
A
M
D
R
L
V
C
G
D
VGFGKT
E
V
A
M
R
A
A
F
L
A
---
V
-------
D
N
H
K
Q
V
A
V
L
V
P
T
T
L
L
A
-------
Q
-------
Q
-------
H
-
Y
D
N
F
R
D
R
F
A
-----
N
W
P
V
--
R
I
-
E
M
I
S
-
R
F
R
S
A
K
E
Q
T
Q
I
L
A
E
-
V
A
E
GK
I
D
I
L
I
G
T
H
K
L
L
Q
S
D
V
K
F
KDLG
L
L
I
-------------------
V
-----
D
E
E
----
H
--
R
---
F
G
V
R
----------------
H
K
-----
E
R
I
--
K
----
A
M
---
R
--
A
N
V
---
D
-
I
L
T
L
----
T
A
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PIP
R
T
L
N
M
A
M
-
S
G
M
R
-
D
L
S
I
I
A
T
--
P
P
A
RR
L
A
V
K
T
F
V
R
E
YD
S
M
V
V
R
E
A
I
L
R
E
I
L
R
G
G
-
Q
V
Y
Y
L
Y
N
D
V
E
N
I
Q
K
A
-
A
E
R
L
A
E
L
V
--
P
E
A
R
I
A
I
G
H
G
QMR
E
R
E
L
E
R
V
M
N
D
F
-
H
H
Q
R
F
--------
N
------
V
L
V
C
T
T
I
I
E
T
G
I
D
-----
I
P
T
A
N
T
-----------
I
I
I
E
R
ADH
F
G
L
A
Q
L
----
H
Q
L
R
G
-
R
-----
V
---
G
R
S
H
H
Q
A
Y
A
W
L
L
TP
H
P
K
A
M
T
T
D
A
Q
K
R
L
--
E
A
I
A
S
L
E
D
L
G
A
--
G
F
A
L
A
T
H
D
L
E
I
R
G
A
G
E
L
L
G
-
E
------
E
----
Q
S
G
S
M
E
T
I
G
F
S
L
Y
M
E
L
-
L
E
N
A
V
D
A
L
K
A
GREPSLEDLTSQQ
T
E
V
E
L
R
M
P
S
L
L
P
D
D
F
I
P
D
V
N
T
R
L
S
F
Y
K
R
I
A
S
AK
T
E
N
E
L
E
E
I
K
V
E
L
I
D
R
F
G
L
L
P
D
P
A
R
T
L
L
D
I
A
R
L
R
Q
Q
A
Q
K
L
G
I
R
K
L
E
G
N
EK
G
G
V
I
E
F
A
EKNHVN
P
A
W
L
-
I
G
L
L
Q
K
-
Q
P
Q
H
Y
--
R
L
D
G
PT
R
L
K
F
I
Q
D
L
S
E
R
K
T
R
I
E
W
V
R
Q
F
M
R
E
L
E
E
N
AI
52
Fugue
58.56
18%
-65
- C4 -
4CCZ
1
METH_HUMAN
A:
[4-638]
----------------------------------------------------
T
L
R
D
E
I
N
A
I
L
Q
K
-----------------------
R
-------------------------
I
M
V
L
D
G
G
M
G
T
M
I
--
Q
R
E
K
L
E
E
H
F
R
----
G
Q
E
F
K
D
H
A
R
P
L
---
K
G
N
N
D
I
L
S
I
T
---
Q
P
D
----
V
I
Y
-
Q
----
I
H
K
E
-
Y
L
L
------
A
D
I
I
E
------
T
N
T
F
S
-
S
--------------------------------------------------------------
T
S
I
-
A
Q
A
D
Y
------
G
L
E
H
L
A
Y
R
M
-------
N
M
C
S
A
G
V
A
R
K
A
A
----
E
E
-----------------
V
----------------
T
L
Q
T
G
I
K
R
F
V
A
G
A
L
G
P
T
N
K
---------------------
T
L
S
V
S
----------
P
-----------
S
-----
V
E
R
P
D
Y
--
R
N
I
T
--------
F
D
E
------------------------------------
L
V
E
A
Y
Q
E
Q
A
K
G
L
L
D
G
G
V
D
I
-
L
L
I
E
------------------
T
I
F
D
T
A
---
N
A
K
A
A
L
F
---
A
--
L
Q
-
N
L
--
F
E
E
-
K
-----
Y
A
P
R
P
I
F
I
S
---
G
-------------------------------
T
I
V
D
K
S
G
R
T
--------
L
S
G
Q
T
----
G
E
G
F
V
I
S
V
S
H
G
E
P
------------
L
C
I
G
L
N
C
A
L
------
G
-----
A
A
E
M
R
P
--------
F
-
I
-----
E
I
---
I
G
K
---
C
T
T
A
Y
V
L
C
Y
P
-
N
A
G
F
A
M
D
-
G
L
V
N
I
V
--
G
G
---------
C
C
G
S
T
P
D
H
I
R
E
I
A
E
A
V
K
N
C
K
P
R
V
P
P
A
T
-------------------
A
F
E
G
H
M
L
L
S
-
G
L
E
P
F
R
I
G
P
--------------------------------------------------------------------------------
Y
T
N
F
V
N
I
-------
G
-------
E
-------
R
-
C
N
V
A
G
S
R
K
F
-----
A
K
L
I
--
M
A
G
N
Y
E
E
-
A
L
C
V
A
K
V
Q
V
E
M
G
A
Q
-
V
----
L
D
V
N
M
D
D
G
M
L
D
G
P
S
A
M
T
-----
R
F
-------------------
C
-----
N
L
I
----
A
--
S
--------------------------------
E
--
P
----
D
I
---
A
--
K
V
P
---
L
-
C
I
D
S
----
S
N
F
-------
A
V
I
-
E
A
G
L
-
K
C
C
--------
Q
---------------------------
G
K
-
C
I
V
N
---
S
I
S
-
L
K
E
G
-
E
D
D
F
L
E
K
A
--
R
--------------
K
I
K
K
Y
-
G
A
A
-
M
V
V
M
------------------------------------------------------------
A
F
D
E
E
----
G
Q
A
T
E
-
T
-----
D
--
T
K
I
R
V
C
T
R
A
Y
H
L
L
--
V
K
K
L
G
F
N
P
N
D
I
I
F
D
-
P
N
I
L
T
-----
I
--
G
T
G
M
E
E
H
N
L
Y
A
I
N
F
I
H
A
T
K
-
V
------
I
----
K
E
T
L
P
G
A
------------------------------------
R
I
S
G
G
L
S
N
L
S
F
S
F
-----
R
-----------
G
M
E
A
I
R
E
A
M
H
G
V
F
L
Y
H
A
I
K
S
G
M
D
M
G
I
V
N
A
G
N
L
P
V
Y
D
D
I
-
H
-
K
E
L
L
Q
-----
L
C
E
--------
D
L
I
W
-
N
K
D
P
E
A
-
T
E
K
L
L
--
R
---------
Y
A
Q
-----------------------
51
Fugue
56.45
16%
-54
- C1 -
4WRT
2
?
B:
[10-758]
------------------------------------------------
M
N
I
N
P
Y
F
L
F
I
D
V
P
I
Q
A
-----------------------
A
I
S
T
T
F
P
Y
T
G
V
----
P
P
Y
S
----------
H
G
T
G
T
G
Y
T
I
--
D
T
V
I
-
R
T
H
E
Y
----
S
N
-------------------------
K
G
K
----
Q
Y
I
-
S
----
D
V
T
G
-
C
T
M
------
V
D
P
T
N
G
P
L
P
E
D
N
E
P
S
A
-----------------
Y
A
Q
L
D
C
V
L
E
A
L
D
R
M
D
E
E
--
H
P
G
L
F
Q
-------
A
A
S
Q
N
A
M
E
T
L
M
V
T
T
V
D
K
L
-
T
Q
G
R
Q
------
T
F
D
W
T
V
C
R
N
QP-----
A
A
T
A
L
N
T
T
I
T
S
F
----
R
L
-----------------
N
----------------
D
-------
L
N
G
A
D
K
G
G
L
I
P
F
C
Q
-
D
-------------
I
I
D
S
L
D
R
P
--------------------------------------------------
E
------------------------------------
M
T
F
F
S
V
K
N
I
K
K
K
L
P
A
K
N
R
K
G
F
L
I
K
R
I
P
M
K
V
K
D
-----
K
-
I
T
K
V
E
Y
I
K
R
A
L
S
L
N
T
M
T
K
D
---
A
--
E
R
-
G
K
--
L
K
R
-
R
-----
A
I
A
T
A
G
I
Q
I
---
R
G
F
V
L
V
V
E
N
L
A
K
N
I
C
E
N
L
E
Q
SGLPVGG
N
E
K
K
A
K
L
S
N
A
V
A
K
M
------
L
S
N
C
P
P
------
G
G
I
S
M
T
V
T
G
D
N
T
------------
K
W
N
E
C
L
N
P
R
------
I
-----
F
L
A
M
T
E
--------
R
-
I
-----
T
R
---
D
S
P
---
I
W
F
R
D
F
C
S
I
A
-
P
V
L
F
S
N
K
I
A
R
L
G
K
G
--
F
M
---------
I
T
S
K
T
K
R
L
K
A
Q
I
-----
P
C
P
D
L
F
S
-------------------------------------
I
P
L
E
R
Y
N
E
E
-------
T
R
A
K
-
L
K
K
L
K
P
F
-----
F
N
E
E
G
T
A
S
--
L
S
P
---------
G
M
M
M
G
M
F
N
M
---
L
-------
S
T
V
L
G
V
A
A
L
G
I
K
N
I
G
N
-------
K
-------
E
-----------
Y
L
W
D
----------
G
L
--
Q
S
-
S
----
D
D
F
A
L
F
V
N
A
K
D
E
E
T
-
C
----
M
E
G
I
N
D
F
----
Y
R
T
C
K
L
-----
L
G
-------------------
I
-----
N
M
S
----
K
--
K
---------------------------------------------------------------------------------------
K
S
Y
--
C
N
E
---------------------------
T
G
-
M
F
E
F
---
T
S
M
F
Y
R
D
G
F
V
S
N
F
A
M
E
L
--
P
--------------
S
F
-----
G
V
-
A
G
V
N
E
--------
S
------
A
D
M
A
I
G
M
T
I
I
K
N
N
-----
M
I
N
N
G
M
G
P
A
T
A
Q
T
A
I
Q
L
F
I
A
D
Y
---
R
Y
T
Y
K
C
----
H
R
G
D
S
-
K
-----
V
--
E
G
-
K
R
M
K
I
I
K
E
L
W
--
E
N
T
K
G
R
D
G
L
L
V
A
D
GG
P
N
I
Y
N
L
R
N
L
H
I
--
P
E
I
V
L
K
Y
N
L
M
D
P
E
Y
K
G
R
L
L
-
H
------
P
----
Q
N
P
F
V
G
------
H
L
S
--
I
E
G
I
K
E
A
D
I
--------------
T
K
M
D
Y
D
A
V
S
G
T
H
S
W
R
T
K
R
N
R
S
I
-----------
L
N
T
D
Q
R
N
M
I
L
E
E
-
Q
C
Y
A
K
C
C
N
L
F
E
A
C
F
N
S
A
S
Y
R
K
P
V
G
-
Q
H
-
S
M
L
E
A
-----
M
A
H
--------
R
L
R
M
-
D
A
R
L
D
Y
-
E
S
G
R
M
S
K
D
D
----
F
E
K
A
M
A
H
L
G
E
I
-------------------
27
HHSearch
54.31
18%
-90
- C6 -
3LKD
-
?
A:
[154-410]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
Q
T
V
A
-
A
V
M
K
E
L
A
V
L
D
V
A
-----
G
-
H
A
G
D
M
L
G
D
A
---
Y
E
Y
L
I
G
Q
F
A
T
D
------
K
--
A
G
E
-
F
-----
Y
T
P
Q
P
V
A
K
L
---
M
T
Q
I
A
F
L
G
--------------------------
R
E
D
K
Q
G
F
------
T
L
Y
D
A
T
M
----
G
S
G
S
L
L
L
N
A
K
R
Y
S
------------
R
Q
P
----------------------------------------------------
Q
T
V
V
Y
F
G
Q
E
-
L
N
T
S
T
Y
N
L
A
R
M
N
M
I
--
L
H
---------
G
V
P
-------------------
I
E
N
Q
F
L
H
N
A
D
T
--
L
D
E
D
W
P
T
Q
---
E
P
T
N
F
D
G
V
L
-
M
N
P
P
Y
S
A
K
W
S
A
S
S
G
-------
F
M
D
D
P
R
F
S
P
F
G
--------
K
L
A
P
K
S
K
A
D
F
A
---------
F
L
L
H
G
Y
Y
H
L
---
K
Q------
D
-
N
G
V
M
A
I
V
L
P
H
G
V
L
F
-------
R
-------
G
N------
A
-
E
G
T
I
R
K
A
L
L
E
----
E
G
A
I
D
T
V
I
-
G
L
P
A
-
N
I
F
F
-------
N
T
S
-
I
----
P
T
T
V
I
I
L
K
K
N
R
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
Fugue
54.25
13%
-83
- C6 -
3UFB
-
?
A:
[12-495]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
Q
P
M
T
T
A
Q
Q
-------
L
G
A
I
V
K
S
S
R
Q
I
M
R
K
D
K
G
L
-
N
G
D
L
D
------
R
L
P
M
L
T
W
I
M
-------
F
L
K
F
L
D
D
L
E
Q
M
R
----
E
T
-----------------
E
A
V
L
E
G
K
S
F
Q
P
AIEAPY
R
W
R
D
W
A
A
I
E
G
G
I
T
G
D
E
L
I
A
F
I
N
N
D
-------------
E
A
M
R
P
D
G
T
----------
R
-----------
G
-----
I
G
L
F
A
Y
L
-
R
S
L
Q
GDNGGD
R
R
D
V
I
------------------------------------
A
T
V
F
K
G
M
Q
N
R
M
I
N
G
Y
L
L
R
D
-
V
V
D
K
I
N
G
I
H
F
N
S
-----
S
-
E
E
M
H
T
L
S
R
L
---
Y
E
T
M
L
R
E
---
M
--
R
D
-
A
A
GD
S
G
E
-
F
-----
Y
T
P
-----
R
---
P
V
V
R
F
M
V
E
V
M
D
------------------------
P
Q
L
G
E
-------
S
V
L
D
P
A
C
----
G
T
G
G
F
L
V
E
A
F
E
H
L
------------
E
R
Q
C
K
T
-
V
E
------
D
-----
R
E
V
L
Q
E
------------------------------
S
S
I
F
G
G
E
-
A
K
S
L
P
Y
L
L
V
Q
M
N
L
L
--
L
H
---------
G
L
E
Y
P
---------------------
R
I
D
P
E
N
S
--
L
R
F
P
L
R
E
M
G
D
K
D
R
V
D
--
V
I
L
-
T
N
P
P
F
G
G
E
E
E
K
G
I
L
-------
G
N
------
F
P
E
D
-----
M
-
Q
T
A
E
T
A
M
L
F
L
Q
---------
L
I
M
R
K
L
K
R
P
GHG
S
-------
D
N
G
G
R
A
A
V
V
V
P
N
G
T
L
F
-------
S
-------
D
-------
G
-
I
S
A
R
I
K
E
E
L
-----
L
K
N
F
--
N
L
-
H
T
I
V
-
R
L
P
E
G
V
F
A
P
Y
T
D
I
A
-
G
----
N
L
L
F
F
D
R
S
G
P
T
D
D
I
W
Y
Y
-----
Q
I
T
V
P
EGRKKYTKTKPMESHE
F
-----
D
E
C
----
L
--
N
---
W
-------------------
W
S
-----
N
R
I
--
V
N
QN
A
W
K
---
E
--
S
A
S
---
E
-
I
I
K
Y
----
S
E
S
-------
G
Q
L
-
I
D
V
N
L
D
R
K
N
P
N
S
--
L
E
V
---------------------------
L
E
-
H
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
50.27
14%
-101
- C6 -
3UFB
-
?
A:
[19-416]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
Q
-------
L
G
A
I
V
K
S
S
R
Q
I
M
R
K
D
K
G
L
-
N
-
G
D
L
------
D
R
L
P
M
L
T
W
I
-------
M
F
L
K
F
L
D
D
L
E
Q
M
----
R
E
T
E
A
V
L
E
G
K
S
F
Q
P
AIEAP
Y
----------------
R
W
R
D
W
A
A
I
E
G
G
I
T
G
D
E
L
I
A
F
I
N
-
N
DEAMRPDGTRGIG
L
F
A
Y
L
R
S
L
----------
Q
-----------
G
---------
D
N
G
-
G
D
R
R
--------
D
V
I
------------------------------------
A
T
V
F
K
G
M
-
Q
N
R
M
I
N
G
Y
L
L
R
-
D
V
V
D
K
I
N
G
I
H
F
N
-----
S
S
E
E
M
H
T
L
S
R
L
---
Y
E
T
M
L
R
E
---
M
R
D
A
A
-
G
D
--
S
G
E
-
F
-----
Y
T
P
R
P
V
V
R
F
---
M
V
E
V
M
D
------------------------------
P
Q
L
G
E
------
S
V
L
D
P
A
C
----
G
T
G
G
F
L
V
E
A
F
E
H
L
------------
E
R
Q
C
K
T
V
------------------------------------
E
D
---
R
E
V
---
L
Q
E
S
S
I
F
G
G
E
-
A
K
S
L
P
Y
L
L
V
Q
M
N
L
L
--
L
H
---------
G
L
---------------------
E
Y
P
R
I
D
P
E
N
S
--
L
R
F
P
L
R
E
M
G
D
--
K
D
R
V
D
V
I
L
-
T
N
P
P
F
G
G
E
E
E
K
G
I
--------------
L
G
N
F
P
--------
E
D
M
Q
T
A
E
T
A
M
L
---------
F
L
Q
L
I
M
R
K
L
---
K
RPGHGSD
N
-
G
G
R
A
A
V
V
V
P
N
G
T
L
F
-------
S
-------
D
G
------
I
-
S
A
R
I
K
E
E
L
L
K
----
N
F
N
L
H
T
I
V
-
R
L
P
E
-
G
V
F
A
P
------
Y
T
D
-
I
----
A
G
N
L
L
F
F
D
R
S
G
P
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
48.40
15%
-116
- C6 -
2IH2
5
MTTA_THEAQ
A:
[21-412]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-----
E
T
P
P
E
V
V
D
F
---
M
V
S
L
A
E
------------------------------
A
P
R
G
G
------
R
V
L
E
P
A
C
----
A
H
G
P
F
L
R
A
F
R
E
A
H
------------
G
------------------------------------------------------
T
A
Y
R
F
V
G
V
E
-
I
D
P
K
A
L
D
L
P
P
W
A
-----------------------------------------
E
G
I
L
A
D
F
--
L
L
W
E
-----
P
--
G
E
A
F
D
L
I
L
-
G
N
P
P
Y
G
I
V
G
E
A
S
K
Y
P
I
H
V
F
K
A
V
K
D
L
-
Y
K
K
A
F
S
--------
T
W
K
G
K
Y
N
L
Y
G
A
---------
F
L
E
K
A
V
R
L
L
---
K
-------
P
-
G
G
V
L
V
F
V
V
P
A
T
W
L
V
-------
L
-------
E
-------
D
-
F
A
L
L
R
E
F
L
A
R
----
E
G
K
T
S
-
V
Y
-
Y
L
G
--
E
V
F
P
-------
Q
K
K
-
V
----
S
A
V
V
I
R
F
Q
K
S
G
K
G
--
L
S
-----
L
W
-------------------
D
-----
T
Q
E
S
ES
G
F
T
P
I
L
W
A
E
-------------------
Y
P
-----
H
W
E
GE
I
----
I
R
---
F
--
E
T
E
---
E
T
R
K
L
E
----
I
S
G
-------
M
P
L
-
G
D
L
F
-
H
I
R
F
A
A
R
--
S
P
E
---------------------------
F
K
-
K
H
P
-----------
A
-
V
--
R
K
E
P
G
--
P
--------------
G
L
V
P
V
L
T
G
R
-
N
L
K
P
G
--------
W
----------
V
D
Y
E
K
N
H
-----------
S
--------------
G
L
W
---
M
P
K
-------
E
---
R
-------
A
------
K
E
L
R
D
F
Y
-
A
---------
T
P
H
L
V
V
--
A
H
T
K
G
---
T
R
V
--
V
A
A
W
D
E
R
A
Y
-
P
W
R
E
E
F
H
L
L
-
P
K
E
GVRL
D
----
P
S
S
L
V
Q
W
L
N
S
E
A
M
Q
K
H
-
V
R
T
L
Y
R
D
----------------
F
V
P
H
L
T
L
R
-
M
L
E
R
L
P
V
R
R
E
Y
G
F
-----------
H
--------------------------------------------------------------------------------------------------------------------
30
HHSearch
47.46
15%
-131
- C6 -
3UZU
1
RSMA_BURPS
A:
[18-207]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
R
--
F
G
Q
N
F
-----
L
V
D
H
G
V
I
D
A
---
I
V
A
A
I
R
------------------------------
P
E
R
G
E
------
R
M
V
E
I
G
P
----
G
L
G
A
L
T
G
P
V
I
A
R
L
------------
A
T
-----------------------------------------------------
P
G
S
P
L
H
A
V
E
-
L
D
R
D
L
I
G
R
L
E
Q
R
F
G
------------------------------------
E
L
L
E
L
H
A
G
D
A
--
L
T
F
D
F
G
S
I
A
R
P
G
D
E
P
S
L
R
I
I
-
G
N
L
P
Y
N
I
S
S
P
--------------------------------------------------
L
L
F
H
L
M
S
F
A
---
P
-------
V
-
V
I
D
Q
H
F
M
L
Q
N
E
V
V
E
-------
R
M
V
AEPGT
K
-------
A
-
F
S
R
L
S
V
M
L
Q
Y
----
R
Y
V
M
D
K
L
I
-
D
V
P
P
-
E
S
F
Q
P
P
------
P
K
-
V
----
D
S
A
I
V
R
M
I
P
H
A
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
47.01
12%
-118
- C6 -
2F8L
7
?
A:
[67-307]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
L
-
K
L
Q
A
S
Y
E
S
I
E
L
E
-----
N
F
S
N
E
E
I
R
K
G
L
---
Q
L
A
L
L
K
G
---
M
--
K
H
G
I
Q
--
V
N
H
-
Q
-----
M
T
P
D
S
I
G
F
----
I
V
A
Y
L
L
E
K
V
-------------------------
I
Q
K
K
K
N
V
------
S
I
L
D
P
A
C
----
G
T
A
N
L
L
T
T
V
I
N
Q
L
------------
E
L
K
G
--------------------------------------------------
D
V
D
V
H
A
S
G
V
D
-
V
D
D
L
L
I
S
L
A
L
V
G
A
D
--
L
Q
---------
R
----------------------
Q
K
M
T
L
L
H
Q
D
G
--
L
A
N
L
L
-------
V
D
P
V
D
V
V
I
-
S
D
L
P
V
G
Y
Y
P
D
D
E
N
A
---------
K
-----
T
F
E
L
-----
C
-
R
E
E
G
H
S
F
A
H
F
L
---------
F
I
E
Q
G
M
R
Y
T
---
K
-------
P
-
G
G
Y
L
F
F
L
V
P
D
A
M
F
G
-------
T
-------
S
-------
D
-
F
A
K
V
D
K
F
I
K
K
----
N
G
H
I
E
G
I
I
-
K
L
P
E
-
T
L
F
K
-------
S
-
Q
-
A
----
R
K
S
I
L
I
L
E
K
A
D
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
46.30
17%
-74
- C6 -
2AR0
2
T1MK_ECOLI
A:
[7-371]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
-------
L
V
A
K
L
W
K
L
C
D
N
L
R
D
G
G
V
----
S
Y
Q
------
N
Y
V
N
E
L
A
S
L
-------
L
F
L
K
M
C
K
E
T
G
Q
E
AEYL
P
E
G----------------
Y
----------------
R
W
D
D
L
K
S
R
----
I
G
Q
E
Q
L
Q
F
Y
R
-
K
-------------
M
L
V
H
L
G
E
D
--------------------------------------
D
K
--------
K
L
V
------------------------------------
Q
A
V
F
H
N
V
-
S
T
T
I
T
E
P
K
Q
I
T
-
A
L
V
S
N
M
D
S
L
D
W
------------------------------------------
Q
-
Y
-----
F
T
P
R
P
L
I
K
T
---
I
I
H
L
L
K
------------------------------
P
Q
P
R
E
------
V
V
Q
D
P
A
A
----
G
T
A
G
F
L
I
E
A
D
R
Y
V
------------
K
S
Q
T
N
D
L
D
D
------------
L
-------------
D
-
G
-----
D
T
---
Q
D
F
---
Q
I
H
R
A
F
I
G
L
E
-
L
V
P
G
T
R
R
L
A
L
M
N
C
L
--
L
H
---------
D
I
E
G
N
----------------
L
D
H
G
G
A
I
R
L
G
N
T
--
L
G
S
D
G
E
N
-----
L
P
K
A
H
I
V
A
-
T
N
P
P
F
G
S
A
A
G
T
N
--------------
I
T
R
T
F
V
----------
H
P
T
S
N
K
Q
L
C
---------
F
M
Q
H
I
I
E
T
L
---
H
-------
P
-
G
G
R
A
A
V
V
V
P
D
N
V
L
F
-------
E
-------
G
G
------
K
-
G
T
D
I
R
R
D
L
M
D
----
K
C
H
L
H
T
I
L
-
R
L
P
T
-
G
I
F
Y
-------
A
Q
G
-
V
----
K
T
N
V
L
F
F
T
K
G
T
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
43.80
15%
-74
- C6 -
3KHK
1
?
A:
[159-448]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
G
I
L
N
R
-
I
S
Q
Y
Q
L
D
A
D
K
L
I
-
G
L
I
N
E
F
--------------
S
K
D
I
L
G
H
V
---
Y
E
Y
F
L
G
Q
F
A
L
A
--
E
G
-
K
Q
--
G
G
Q
-
Y
-----
Y
T
P
K
S
I
V
T
L
---
I
V
E
M
L
E
-------------------------------
P
Y
K
G
------
R
V
Y
D
P
A
M
----
G
S
G
G
F
F
V
S
S
D
K
F
I
------------
E
K
H
A
N
V
K
H
Y
----------------------------------
N
A
---
S
E
Q
---
K
K
Q
I
S
V
Y
G
Q
E
-
S
N
P
T
T
W
K
L
A
A
M
N
M
V
--
I
R
---------
G
I
D
--------------------
F
N
F
G
K
K
N
A
D
S
--
F
L
D
D
Q
H
---
P
--
D
L
R
A
D
F
V
M
-
T
N
P
P
F
N
M
K
D
W
W
H
E
K
-------
L
A
D
D
-
P
R
W
T
I
N
T
NKR--
I
-
L
T
P
P
T
G
N
A
N
F
A
---------
W
M
L
H
M
L
Y
H
L
---
A
-------
P
-
T
G
S
M
A
L
L
L
A
N
G
S
M
S
-------
S
-------
N
TN-----
N
-
E
G
E
I
R
K
T
L
V
E
----
Q
D
L
V
E
C
M
V
-
A
L
P
G
-
Q
L
F
T
-------
N
T
Q
-
I
----
P
A
C
I
W
F
L
T
K
D
K
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
43.38
23%
-84
- C2 -
3OC3
-
?
A:
[255-462]
---------------------------------------------------------------------------------------------
I
Y
P
L
I
----
G
P
N
D
I
I
E
--
Q
L
V
G
F
L
D
S
G
D
W
Q
V
---
Q
F
S
G
-
L
I
A
L
G
----
Y
L
K
E
F
V
E
D
K
D
G
L
C
R
K
L
V
S
L
L
S
S
P
D
---
E
D
I
----
K
L
L
-
S
----
A
E
L
L
C
H
F
P
------
I
T
D
--------------
S
-
L
D
L
---
V
L
-
E
K
---------
C
W
K
N
I
E
S
E
E
L
-----
I
S
V
S
-------
K
T
S
N
L
S
L
L
T
K
I
Y
R
E
N
P
E
L
S
I
P
P
E
R
------
L
K
D
I
F
P
------------
C
F
T
S
P
V
P
E
V
------
R
-----------------
T
----------------
S
I
L
N
M
V
K
N
L
S
E
E
---
S
I
D
F
L
V
A
-
E
-------------
V
V
L
I
E
E
K
D
----------
E
I
R
E
M
A
I
K
L
L
K
K
R
-----
R
D
L
P
K
N
L
I
L
H
F
M
--------
N
V
I
------------------------------------
G
G
S
L
Y
E
P
Y
S
E
D
D
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
Fugue
42.80
12%
-67
- C6 -
3KHK
1
?
A:
[7-530]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
Q
F
-------
L
N
D
L
D
N
Q
L
W
R
A
A
D
K
L
R
S
N
-
L
D
-
A
A
------
N
Y
K
H
V
V
L
G
L
-------
I
F
L
K
Y
V
S
D
A
F
E
E
----
R
Q
-----------------
Q
----------------
E
L
T
E
L
F
Q
K
-
D
D
D
D
N
I
Y
Y
L
P
R
E
D
-
Y
-------------
D
S
D
E
A
Y
Q
Q
----------
A
-----------
I
-----
A
E
E
L
E
I
G
-
D
Y
Y
T
---------
E
K
------------------------------------
N
V
F
W
V
P
K
T
A
R
W
N
K
L
R
D
V
I
T
-
L
P
T
S
V
S
W
L
I
D
N
A
F
D
D
I
E
K
-
A
N
P
K
L
K
G
I
L
---
N
R
I
S
Q
Y
Q
L--
D
--
A
D
-
K
L
--
I
G
L
-
I
-----
N
E
F
S
K
D
I
L
G
---
H
V
Y
E
Y
F
L
G
Q
F
A
L
A
E
G
K
Q
G
G
Q
-------
Y
Y
T
P
K
S
I
V
T
L
I
V
E
M
L
EPYK
G
R
V
Y
D
P
A
M
----
G
S
G
G
F
F
V
S
S
D
K
F
I
------------
E
K
H
A
N
V
K
----------------------------
H
-
Y
-----
N
A
---
S
E
Q
---
K
K
Q
I
S
V
Y
G
Q
E
-
S
N
P
T
T
W
K
L
A
A
M
N
M
V
--
I
-----------
R
G
I
D
F
N
F
G
K
K
N
A
D
S
F
L
D
D
Q
H
P
D
L
R
A
D
F
V
M
T
N
P
PF
N
M
K
D
W
W
H
--
E
K
L
A
D
D
P
R
W
T
I
-
N
T
N
K
R
I
L
T
P
P
T
G
N
A
-------
N
F
A
W
-
M
L
H
M
L
Y
H
-----
L
-
A
P
T
G
S
M
A
L
L
L
A
---------
N
G
S
M
S
S
N
T
N
---
N
-------
E
G
E
I
R
K
T
L
V
E
Q
D
L
V
-----------------
E
-------
C
-
M
V
A
L
P
G
Q
L
F
TNTQ
I
P
A
C
I
--
W
F
-
L
T
K
D
-
K
N
A
K
N
G
K
R
D
R
R
G
Q
V
-
L
----
F
I
D
A
R
K
L
G
Y
M
K
D
R
V
L
R
D
-----
F
K
-------------------
D
-----
E
D
I
----
Q
--
K
---
L
-------------------
A
D
-----
T
F
H
--
N
----
W
Q
Q
EW
S
--
E
E
N
---
N
-
Q
A
G
F
----
C
F
S
-------
A
D
L
-
A
L
I
R
-
K
N
D
F
V
L
T
--
P
G
R
---------------------------
Y
V
-
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
42.62
15%
-128
- C6 -
1QYR
-
RSMA_ECOLI
A:
[18-199]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
-
F
-----
L
N
D
Q
F
V
I
D
S
---
I
V
S
A
I
N
------------------------------
P
Q
K
G
Q
------
A
M
V
E
I
G
P
----
G
L
A
A
L
T
E
P
V
G
E
R
---------------------------------------------------------------------
L
D
Q
L
T
V
I
E
-
L
D
R
D
L
A
A
R
L
Q
T
H
P
F
--
L
--------------------------------
G
P
K
L
T
I
Y
Q
Q
D
A
--
M
T
F
N
F
G
E
L
A
E
-
K
M
G
Q
P
L
R
V
F
-
G
N
L
P
Y
N
I
S
T
P
--------------------------------------------------
L
M
F
H
L
F
S
Y
T
---
D
-------
A
-
I
A
D
M
H
F
M
L
Q
K
E
V
V
N
-------
R
-------
L
V
AGPNSK
A
-
Y
G
R
L
S
V
M
A
Q
Y
----
Y
C
N
V
I
P
V
L
-
E
V
P
P
-
S
A
F
T
P
P
------
P
K
-
V
----
D
S
A
V
V
R
L
V
P
H
A
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
41.91
14%
-112
* C6 *
3TMA
-
?
A:
[203-322]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
G
M
------
R
V
L
D
P
F
T
----
G
S
G
T
I
A
L
E
A
A
S
T
L
------------
G
------------------------------------------------------
P
T
S
P
V
Y
A
G
D
-
L
D
E
K
R
L
G
L
A
R
E
A
A
L
--
A
S
---------
G
L
---------------------
S
W
I
R
F
L
R
A
D
A
--
R
H
L
P
----
R
F
--
F
P
E
V
D
R
I
L
-
A
N
P
P
H
G
L
----
K
------------------------------
E
G
L
F
H
L
Y
W
D
---------
F
L
R
G
A
L
A
L
L
---
P
-------
P
-
G
G
R
V
A
L
L
T
L
R
P
A
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
40.88
14%
-140
- C6 -
3TQS
-
RSMA_COXBU
A:
[12-192]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
H
F
-----
L
H
D
S
F
V
L
Q
K
---
I
V
S
A
I
H
------------------------------
P
Q
K
T
D
------
T
L
V
E
I
G
P
----
G
R
G
A
L
T
D
Y
L
L
T
E
C
---------------------------------------------------------------------
D
N
L
A
L
V
E
-
I
D
R
D
L
V
A
F
L
Q
K
K
Y
N
--
Q
--------------------------------
Q
K
N
I
T
I
Y
Q
N
D
A
--
L
Q
F
D
F
S
S
V
---
K
T
D
K
P
L
R
V
V
-
G
N
L
P
Y
N
I
S
T
P
L
---------------
L
F
-----------------------------------
H
L
F
S
Q
I
---
H
-------
C
-
I
E
D
M
H
F
M
L
Q
K
E
V
V
R
R
I
T
AEVG
S
-------
H
-------
D
-
Y
G
R
L
S
V
M
A
Q
Y
----
F
C
D
N
T
Y
L
F
-
T
V
S
P
-
Q
A
F
T
P
P
------
P
R
-
V
----
E
S
A
I
I
R
L
I
P
R
H
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
39.24
13%
-83
- C6 -
3V97
3
RLMKL_ECOLI
A:
[166-404]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
-
D
R
--
A
G
I
-
A
-----
P
I
K
E
T
L
A
A
A
---
I
V
M
R
S
G
------------------------------
W
Q
P
G
T
------
P
L
L
D
P
M
C
----
G
S
G
T
L
L
I
E
A
A
M
L
A
------------
T
D
R
A
P
G
L
H
R
GRWGFS
G
-----
W
A
Q
H
D
E
A
-------
I
-
W
Q
E
V
K
A
E
A
Q
T
R
A
R
K
G
L
A
E
Y
S
S
H
F
Y
G
S
D
-
S
D
A
R
V
I
Q
R
A
R
T
N
A
R
--
L
A
---------
G
I
G
--------------------
E
L
I
T
F
E
V
K
D
V
--
A
Q
L
T
N
P
--
L
P
--
K
G
P
Y
G
T
V
L
-
S
N
P
P
Y
G
E
---
S
E
P
-----------
A
-
L
------------------
I
A
L
H
-
S
---------
L
L
G
R
I
M
K
N
Q
---
F
-------
G
-
G
W
N
L
S
L
F
S
A
S
P
D
L
L
-------
S
-------
C
-------
L
Q
L
R
A
D
K
Q
Y
K
A
K
----
N
G
P
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
37.14
15%
-98
- C6 -
3LDU
9
?
A:
[195-368]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
G
R
------
V
L
V
D
P
M
C
----
G
S
G
T
I
L
I
E
A
A
M
I
G
------------
I
N
M
A
P
G
L
N
R
------
E
FISEK
W
R
T
L
D
K
K
I
W
W
D
V
R
K
D
A
F
-----
N
K
---
I
D
N
---
E
S
K
F
K
I
Y
G
Y
D
-
I
D
E
E
S
I
D
I
A
R
E
N
A
E
--
I
A
---------
G
V
--------------------
D
E
Y
I
E
F
N
V
G
D
A
--
T
Q
F
K
S
-------
E
D
E
F
G
F
I
I
-
T
N
P
P
Y
G
E
R
L
E
D
K
D
-----------
S
-
V
------------------
K
Q
L
Y
K
E
---------
L
G
-
Y
A
F
R
K
L
---
K
-------
N
-
W
S
Y
Y
L
I
T
S
Y
E
D
F
E
Y
-------
E
-------
F
-------
G
-
Q
K
A
D
K
K
R
K
L
Y
----
N
G
M
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------