@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu07010: (2016-06-11 )
MKKQPQQKERVSRWKGTYFKRNFVFILLIACIPGLLTGGAIYFLSIDKVEKELQRSHETQVAREVSRMDEKLGVLELALTQMAYDSSLMNGLAERDLEKDFTFSYQLTKKLFLLRDQQPLIEQASIFLNSPRPLVLSPEYSALTEQEALRKYRSLLASDHSIYWKRSGNQAMLIQLIPGAAEKPFGAIMLAVDPKEMESILQSLSPYPDGSALLLDQNREVLFHEGEKDFEKTLLHEIKKQPAENGHFQMEWKGKVYSVSFGEMNRMHQQWTFVSAAPLSAITAPMVFLSKVIIVMLVICIGLAVCMTWYASKKIYRPIQHLLGLFTGGEKKTWQASGQDEFKWIEKRWQDLSLESRKLQQQLLRQTPHMKKSFLQHLLQSDFYYDNEESLRFRMEEAGWNIGGNVFHVLDLQVTGLRCEKSIFREGDEQLAVFTLTNIAEELAAKRVFQLSILDIGRLSVTVLVMKTNSSDLKAYITELARQFGDVTGLCLTSTLSSKTERVTEIPSLFQDVKCGKSRRKFANRDQVIDLQADFPRDEQFAPYYPFELEKQIVQTIRLERKQEAKELIDGCMKELSEKAAIDRHVHSALIQLFSRIQEDILHSGLNPSELFQHRNPFLDISELREPNEAAAWLMDVVVTPYLSKLEGRKNRQQKQLAERVIAMIHEQYMADISLESCADALGMNSYTLSKAFKQVTGINFIDYVTQIRIEKAKELLVNTNKKIHDVSEEVGYRHNYFNRIFKKQVGMPPGVFRQMYQETP
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.....--..210.......220.......230..-.....240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.--......370.......380.......390.......400...---....410.......420......-------.430.......440.......450------.......460.----......470.......480.......490.......500-..----.....510.......520..--.....530.......540.......550.......560.......570......----------.580.......590.......600.......610..--.....620.-......630.......-------640.......650..-------.....660....---...670.------.......680.......690.......700-.......710.......--720.......730..-.-.-...740..-.....750.......760---------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MKKQ
P
Q
Q
K
E
R
V
S
R
WKG
T
Y
F
KR
N
F
V
F
I
L
L
I
A
C
I
P
G
LLTG
G
A
I
Y
F
L
S
I
D
K
V
E
K
E
L
Q
R
S
H
E
T
Q
V
A
R
E
V
S
R
M
D
E
K
L
G
V
L
E
L
A
L
T
Q
M
A
Y
D
S
S
L
M
N
G
L
A
E
R
D
LEKD
F
T
F
S
Y
Q
L
T
K
K
L
F
L
LRDQQ
P
L
I
E
Q
A
S
I
F
LNSPR
P
L
V
LSP
E
Y
S
A
L
T
E
Q
E
A
L
R
K
Y
R
S
L
LASD
H
S
I
Y
W
KRSG
N
Q
A
M
L
I
Q
LIPGAAEKPF
G
A
I
M
L
A
V
D
P
K
E
M
E
S
I
L
Q
SLSPY--PDG
S
A
L
L
L
DQNR
E
V
L
F
HEGE
K
D
F
E
K
T
L
-
L
H
E
I
K
KQPAENG
H
F
Q
M
E
WKG
K
V
Y
S
V
S
F
G
E
M
N
R
M
H
Q
Q
W
T
F
VSAA
P
L
S
A
I
T
A
P
M
V
F
L
S
K
V
I
I
V
M
L
V
I
C
I
G
L
A
V
C
M
T
W
Y
A
S
K
K
I
Y
R
P
I
Q
H
L
L
G
L
FTGGEK
K
T
WQASG
Q
D
E
F
K
W
I
E
K
R
W
Q
DLS
L
E
S
R
K
L
Q
Q
Q
L
--
L
R
QTP
H
M
K
K
S
F
L
Q
H
L
L
Q
SDFYYDN
E
E
S
L
R
F
R
M
E
EAGWNIGG
N
---
V
F
H
V
L
D
L
Q
V
TGLR
C
E
K
S
I
F
REGD-------E
Q
L
A
V
F
T
L
T
N
I
A
E
E
L
A
A
K
R
V
F
Q
L
S
------
I
L
D
IG
R
L
S
V
T
V
----
L
V
M
KTN
S
S
D
L
K
A
Y
I
T
E
L
A
R
Q
FGDVT
G
L
C
L
T
S
TLSS
K
T
E
R
-
V
T
----
E
I
P
S
L
F
Q
D
V
K
C
G
K
S
R
R
KFAN--RD
Q
V
I
D
LQADFPRDEQFAPYY
P
F
E
L
E
K
Q
I
V
Q
T
I
R
L
E
R
K
Q
E
A
K
E
L
I
D
G
C
M
K
E
L
S
E
----------
K
A
A
I
D
R
H
V
H
S
A
L
I
Q
L
F
S
R
I
Q
E
D
I
L
HSGL
N
P
S
E
L
F
Q
H--RNPFL
D
I
S
E
-LREP
N
E
A
A
A
W
L
M
D
V
V
V
-------
T
P
Y
L
S
K
L
EGRK
N
R
Q
Q
-------
K
Q
L
A
E
R
V
I
A
M
I
H
---
E
Q
Y
M
-
A
D------I
S
L
E
S
C
A
D
A
LGMNS
Y
T
L
S
K
A
F
K
Q
VTG
I
N
F
I
-
D
Y
V
T
Q
I
R
I
E
K
A
K
E
L
L
V
N--TNKKIH
D
V
S
E
E
VGY
R
-
H
-
N
-
Y
F
N
R
I
F
K
K
-QVGMP
P
G
V
F
R
Q
M
Y
QETP----------
39
Fugue
76.18
16%
-75
- C2 -
4FE7
1
XYLR_ECOLI
A:
[21-409]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
F
T
K
R
H
R
I
T
L
L
F
N
A
N
-------
K
A
Y
D
R
Q
V
V
E
G
V
G
E
Y
L
Q
A
S
Q
S
E
W
D
I
------
F
I
E
E
F
R
W
L
G
D
G
----
V
I
A
D
F
D
D
K
Q
I
E
Q
A
L
A
D
V
D
V
P
I
V
G
V
G
G
S
Y
H
L
A
E
S
Y
P
P
V
H
Y
-
I
A
T
D
N
Y
A
L
V
E
S
A
F
L
H
L
K
E
K
G
V
N
R
F
A
F
Y
G
L
P
E
S
S
G
K
R
W
A
T
E
R
E
Y
A
F
R
Q
L
V
A
E
E
K
Y
R
G
V
V
Y
Q
G
L
E
T
A
P
E
N
W
Q
H
A
Q
N
R
L
A
D
W
L
Q
T
LPPQ
T
G
I
I
A
V
T
D
A
R
A
R
H
I
L
Q
V
C
E
H
L
H
I
P
V
P
E
K
L
C
V
I
G
I
D
N
E
E
L
T
R
Y
LS
R
V
A
L
S
S
V
A
Q
G
A
R
Q
M
G
Y
Q
A
A
K
L
L
H
R
L
L
D
K
E
E
M
P
L
Q
R
I
L
V
P
P
V
R
V
I
E
R
R
S
TDYRSLT
D
P
A
V
I
Q
A
M
H
Y
I
R
---
N
H
A
C
-
K
G
------
I
K
V
D
Q
V
L
D
A
V
G
I
S
R
S
N
L
E
K
R
F
K
E
E
V
G
E
T
I
H
-
A
M
I
H
A
E
K
L
E
K
A
R
S
L
L
I
S
--
T
T
L
S
I
N
E
I
S
Q
M
C
G
Y
P
S
L
-
Q
-
Y
F
Y
S
V
F
K
K
-
A
Y
D
T
T
P
K
E
Y
R
D
V
N
S
E
------------
25
HHSearch
75.16
37%
-144
- C2 -
3LSG
1
?
A:
[2-103]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
A
K
E
L
I
Q
N
I
I
E
---
E
S
Y
T
D
S
Q
------
F
T
L
S
V
L
S
E
K
L
D
L
S
S
G
Y
L
S
I
M
F
K
K
N
F
G
I
P
F
Q
-
D
Y
L
L
Q
K
R
M
E
K
A
K
L
L
L
L
T
--
T
E
L
K
N
Y
E
I
A
E
Q
V
G
F
E
D
V
-
N
-
Y
F
I
T
K
F
K
K
-
Y
Y
Q
I
T
P
K
Q
Y
R
E
----------------
21
HHSearch
74.54
21%
-156
- C2 -
3MN2
2
?
A:
[2-107]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
A
V
R
Q
V
E
E
Y
I
E
---
A
N
W
M
-
R
P
------
I
T
I
E
K
L
T
A
L
T
G
I
S
S
R
G
I
F
K
A
F
Q
R
S
R
G
Y
S
P
M
-
A
F
A
K
R
V
R
L
Q
H
A
H
N
L
L
S
D
GA
T
P
T
T
V
T
A
A
A
L
S
C
G
F
S
N
L
-
G
-
H
F
A
R
D
Y
R
D
-
M
F
G
E
K
P
S
E
T
L
Q
R
A
R
-------------
5
PsiBlast_PDB
73.12
37%
-143
- C2 -
3LSG
1
?
A:
[5-103]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
I
Q
N
I
I
E
---
E
S
Y
T
D
S
Q
------
F
T
L
S
V
L
S
E
K
L
D
L
S
S
G
Y
L
S
I
M
F
K
K
N
F
G
I
P
F
Q
-
D
Y
L
L
Q
K
R
M
E
K
A
K
L
L
L
L
T
--
T
E
L
K
N
Y
E
I
A
E
Q
V
G
F
E
-
D
V
N
-
Y
F
I
T
K
F
K
K
-
Y
Y
Q
I
T
P
K
Q
Y
R
E
----------------
19
HHSearch
72.90
28%
-144
- C2 -
3OOU
1
?
A:
[4-107]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
P
I
I
Q
N
V
L
S
Y
I
T
---
E
H
F
S
-
E
G
------
M
S
L
K
T
L
G
N
D
F
H
I
N
A
V
Y
L
G
Q
L
F
Q
K
E
M
G
E
H
F
T
-
D
Y
L
N
R
Y
R
V
N
Y
A
K
E
E
L
L
Q
--
T
K
D
N
L
T
I
I
A
G
K
S
G
Y
T
D
M
-
A
-
Y
F
Y
R
Q
F
K
K
-
H
T
G
E
T
P
N
R
Y
R
K
I
H
--------------
1
PsiBlast_PDB
72.76
29%
-142
- C2 -
3OOU
1
?
A:
[6-108]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
I
Q
N
V
L
S
Y
I
T
---
E
H
F
S
-
E
G
------
M
S
L
K
T
L
G
N
D
F
H
I
N
A
V
Y
L
G
Q
L
F
Q
K
E
M
G
E
H
F
T
-
D
Y
L
N
R
Y
R
V
N
Y
A
K
E
E
L
L
Q
--
T
K
D
N
L
T
I
I
A
G
K
S
G
Y
T
-
D
-
M
A
Y
F
Y
R
Q
F
K
K
-
H
T
G
E
T
P
N
R
Y
R
K
I
H
Q
-------------
22
HHSearch
68.13
29%
-146
- C2 -
2K9S
-
A:
[3-106]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
R
V
R
E
A
C
Q
Y
I
S
---
D
H
L
A
D
S
N
------
F
D
I
A
S
V
A
Q
H
V
C
L
S
P
S
R
L
S
H
L
F
R
Q
Q
L
G
I
S
V
L
-
S
W
R
E
D
Q
R
I
S
Q
A
K
L
L
L
S
T
--
T
R
M
P
I
A
T
V
G
R
N
V
G
F
D
D
Q
-
L
-
Y
F
S
R
V
F
K
K
-
C
T
G
A
S
P
S
E
F
R
A
G
C
--------------
4
PsiBlast_PDB
67.89
25%
-129
- C2 -
4FE7
-
XYLR_ECOLI
A:
[284-409]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
-------
V
P
P
V
R
V
I
E
R
R
S
T
D
Y
R
-------
S
L
T
D
P
A
V
I
Q
A
M
H
Y
I
R
N
H
A
C
-
K
G
------
I
K
V
D
Q
V
L
D
A
V
G
I
S
R
S
N
L
E
K
R
F
K
E
E
V
G
E
T
I
H
-
A
M
I
H
A
E
K
L
E
K
A
R
S
L
L
I
S
--
T
T
L
S
I
N
E
I
S
Q
M
C
G
Y
P
-
S
L
Q
-
Y
F
Y
S
V
F
K
K
-
A
Y
D
T
T
P
K
E
Y
R
D
V
N
S
E
------------
24
HHSearch
66.64
24%
-188
- C- -
3MKL
-
?
A:
[140-243]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
-------
P
N
M
R
T
R
V
C
T
V
I
N
---
N
N
I
A
-
H
E
------
W
T
L
A
R
I
A
S
E
L
L
M
S
P
S
L
L
K
K
K
L
R
E
E
-
E
T
S
Y
S
-
Q
L
L
T
E
C
R
M
Q
R
A
L
Q
L
I
V
I
--
H
G
F
S
I
K
R
V
A
V
S
C
G
Y
H
S
V
-
S
-
Y
F
I
Y
V
F
R
N
-
Y
Y
G
M
T
P
T
E
Y
Q
E
R
S
--------------
2
PsiBlast_PDB
66.42
34%
-132
- C2 -
2K9S
-
A:
[10-103]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
Y
I
-
S
D
H
L
ADSN
F
D
I
A
S
V
A
Q
H
V
C
L
S
P
S
R
L
S
H
L
F
R
Q
Q
L
G
I
S
V
L
-
S
W
R
E
D
Q
R
I
S
Q
A
K
L
L
L
S
T
--
T
R
M
P
I
A
T
V
G
R
N
V
G
F
D
-
D
-
Q
L
Y
F
S
R
V
F
K
K
-
C
T
G
A
S
P
S
E
F
R
-----------------
17
HHSearch
66.05
26%
-155
- C2 -
4FE7
-
XYLR_ECOLI
A:
[303-409]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
-------
D
P
A
V
I
Q
A
M
H
Y
I
R
---
N
H
A
C
-
K
G
------
I
K
V
D
Q
V
L
D
A
V
G
I
S
R
S
N
L
E
K
R
F
K
E
E
V
G
E
T
I
H
-
A
M
I
H
A
E
K
L
E
K
A
R
S
L
L
I
S
--
T
T
L
S
I
N
E
I
S
Q
M
C
G
Y
P
S
L
-
Q
-
Y
F
Y
S
V
F
K
K
-
A
Y
D
T
T
P
K
E
Y
R
D
V
N
S
E
------------
37
Fugue
64.69
18%
-135
- C2 -
3MN2
2
?
A:
[1-108]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
N
A
V
R
Q
V
E
E
Y
I
E
---
A
N
-
W
M
R
P
------
I
T
I
E
K
L
T
A
L
T
G
I
S
S
R
G
I
F
K
A
F
Q
R
S
R
G
Y
S
-
P
M
A
F
A
K
R
V
R
L
Q
H
A
H
N
L
L
S
D
GA
T
P
T
T
V
T
A
A
A
L
S
C
G
F
S
-
N
L
G
-
H
F
A
R
D
Y
R
D
M
F
G
E
K
P
S
E
T
L
Q
R
A
R
P
-------------
3
PsiBlast_PDB
63.98
25%
-113
- C2 -
4FE4
-
XYLR_ECOLI
A:
[264-389]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
-------
V
P
P
V
R
V
I
E
R
R
S
T
D
Y
R
-------
S
L
T
D
P
A
V
I
Q
A
M
H
Y
I
R
N
H
A
C
-
K
G
------
I
K
V
D
Q
V
L
D
A
V
G
I
S
R
S
N
L
E
K
R
F
K
E
E
V
G
E
T
I
H
-
A
M
I
H
A
E
K
L
E
K
A
R
S
L
L
I
S
--
T
T
L
S
I
N
E
I
S
Q
M
C
G
Y
P
-
S
L
Q
-
Y
F
Y
S
V
F
K
K
-
A
Y
D
T
T
P
K
E
Y
R
D
V
N
S
E
------------
45
Fugue
63.66
18%
-100
- C1 -
4XYW
2
?
A:
[1-338]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
N
V
G
F
I
V
T
K
S
E
I
G
G
A
Q
T
W
V
N
E
I
S
N
L
I
K
E
E
C
N
I
F
L
I
T
S
E
E
G
W
L
T
H
K
D
V
--
F
A
G
V
F
V
I
P
G
I
K
K
Y
F
D
F
L
T
L
F
K
L
R
K
I
L
K
E
N
N
I
S
-----------
T
L
I
A
S
S
A
N
A
G
V
Y
A
R
L
V
R
L
-------
L
V
D
F
K
C
I
Y
V
S
H
G
W
S
C
L
K
S
I
F
C
I
V
E
K
Y
L
S
L
L
T
---
D
V
I
W
C
V
S
K
N
D
E
K
K
A
I
E
----
N
I
G
I
K
E
P
K
I
I
T
V
S
N
S
V
P
Q
M
P
R
C
K
Q
L
Q
Y
K
V
L
F
V
G
R
L
T
H
P
K
------
R
P
E
L
L
A
N
V
I
S
K
K
PQ
Y
S
L
H
I
V
G
S
L
K
K
Q
F
S
E
C
E
N
I
H
F
L
G
E
VNNFYNY
H
E
Y
D
L
F
S
L
I
S
D
S
E
G
L
P
M
S
G
L
E
A
H
T
A
A
I
P
L
L
L
S
D
V
G
G
C
F
E
L
I
EGN
G
L
L
V
E
N
T
E
D
D
I
G
Y
K
L
D
K
I
F
D
D
Y
E
N
Y
R
E
Q
A
I
R
A
S
G
K
F
V
I
E
N
Y
A
S
----
A
Y
K
S
I
I
L
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
63.23
24%
-123
- C2 -
1D5Y
2
ROB_ECOLI
A:
[1-123]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
-------
A
G
I
I
R
D
L
L
I
W
L
E
---
G
H
L
D
-
Q
P
------
L
S
L
D
N
V
A
A
K
A
G
Y
S
K
W
H
L
Q
R
M
F
K
D
V
T
G
H
A
I
G
-
A
Y
I
R
A
R
R
L
S
K
S
A
V
A
L
R
L
--
T
A
R
P
I
L
D
I
A
L
Q
Y
R
F
D
S
Q
-
Q
-
T
F
T
R
A
F
K
K
-
Q
F
A
Q
T
P
A
L
Y
R
R
S
P
E
W
S
A
FGIRPPLRL
G
26
HHSearch
62.93
24%
-133
- C2 -
1D5Y
2
ROB_ECOLI
A:
[3-110]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
I
I
R
D
L
L
I
W
L
E
---
G
H
L
D
-
Q
P
------
L
S
L
D
N
V
A
A
K
A
G
Y
S
K
W
H
L
Q
R
M
F
K
D
V
T
G
H
A
I
G
-
A
Y
I
R
A
R
R
L
S
K
S
A
V
A
L
R
L
--
T
A
R
P
I
L
D
I
A
L
Q
Y
R
F
D
S
Q
-
Q
-
T
F
T
R
A
F
K
K
-
Q
F
A
Q
T
P
A
L
Y
R
R
S
P
E
-------------
16
HHSearch
62.38
19%
-140
- C2 -
3GBG
1
TCPN_VIBC3
A:
[166-272]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
-------
L
D
A
M
E
K
I
S
C
L
V
K
---
S
D
I
T
-
R
N
------
W
R
W
A
D
I
C
G
E
L
R
T
N
R
M
I
L
K
K
E
L
E
-
S
R
G
V
K
F
R
-
E
L
I
N
S
I
R
I
S
Y
S
I
S
L
M
K
T
--
G
E
F
K
I
K
Q
I
A
Y
Q
S
G
F
A
S
V
-
S
-
Y
F
S
T
V
F
K
S
-
T
M
N
V
A
P
S
E
Y
L
F
M
L
T
G
------------
23
HHSearch
61.86
21%
-132
- C2 -
3W6V
2
?
A:
[37-142]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
D
P
L
A
E
V
V
A
W
A
L
---
E
H
L
H
-
E
Q
------
F
D
V
E
T
L
A
A
R
A
Y
M
S
R
R
T
F
D
R
R
F
R
S
L
T
G
S
A
P
L
-
Q
W
L
I
T
Q
R
V
L
Q
A
Q
R
L
L
E
T
--
S
D
Y
S
V
D
E
V
A
G
R
C
G
F
R
S
P
-
V
-
A
L
R
G
H
F
R
R
-
Q
L
G
S
S
P
A
A
Y
R
A
A
Y
R
A
------------
38
Fugue
60.89
10%
-61
- C2 -
3GBG
1
TCPN_VIBC3
A:
[4-273]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
S
-
F
Q
----
T
N
V
Y
R
M
S
K
F
D
T
Y
I
F
N
N
L
Y
I
N
--
D
Y
K
M
F
W
I
D
S
G
I
A
K
L
I
D
K
N
C
L
V
S
Y
E
I
N
S
S
S
I
I
L
L
K
K
N
S
I
Q
R
F
S
L
T
S
L
S
-
D
E
N
I
N
V
----------
S
V
I
T
I
S
D
S
F
I
R
S
L
K
S
Y
I
L
G
N
K
D
L
L
L
W
N
C
E
H
N
D
I
A
V
L
--
S
E
V
V
N
G
F
R
E
-
I
N
Y
S
D
E
F
L
K
V
F
F
S
G
F
F
-------
S
K
V
E
K
K
Y
N
S
I
F
I
T
D
D
-------
L
D
A
M
E
K
I
S
C
L
V
K
---
S
D
I
T
-
R
N
------
W
R
W
A
D
I
C
G
E
L
R
T
N
R
M
I
L
K
K
E
L
E
S
-
R
G
V
K
F
R
-
E
L
I
N
S
I
R
I
S
Y
S
I
S
L
M
K
T
--
G
E
F
K
I
K
Q
I
A
Y
Q
S
G
F
A
S
V
-
S
-
Y
F
S
T
V
F
K
S
-
T
M
N
V
A
P
S
E
Y
L
F
M
L
T
G
V
-----------
20
HHSearch
60.71
19%
-124
- C2 -
3OIO
2
?
A:
[5-112]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
-------
Q
P
K
L
T
E
A
V
S
L
M
E
---
A
N
I
E
-
E
P
------
L
S
T
D
D
I
A
Y
Y
V
G
V
S
R
R
Q
L
E
R
L
F
K
Q
Y
L
G
T
V
P
S
-
K
Y
Y
L
E
L
R
L
N
R
A
R
Q
L
L
Q
Q
--
T
S
K
S
I
V
Q
I
G
L
A
C
G
F
S
S
G
-
P
-
H
F
S
S
T
Y
R
N
-
H
F
N
I
T
P
R
E
E
R
A
Q
R
A
Q
P
-----------