@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu07110: (2016-06-11 )
METVPKKRDAPVLTAGKGISWMAALKRDKWLYLLLIPGLLYFLIFKYLPMWGVLIAFKDYSPYLGFWKSEWVGFDYFKDFFMNPDFFRLLRNTLMLASLDLLFAFPAPLILALLLNEVRKAVYKRCIQTFIYVPHFVSWTIVVSITFVFFTVDTGVINKLIMSLTGEQISFLSDADWFRPMIVMQSIWKETGWGTILFLAALATVDQEQYEAAIMDGAGRFRRMWHITLPAIRSTIIVLLILRIGSFLNLGFEQVYLMTNSLNRSVADIFDTYVYMMGITQGAYSYSTAVGLFKSVVGIILIFGANYIAKKFDQEGLF
Atome Classification :
(20 SA)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10.....-...20........30.......----------.40........-50.........60----........70........----80..-----------.--.----....90........100----........110---.........120.......130.......140.....--..150.......160.......---170......-.180.......190.......200.....-----------------..210......----.220.......230.......-------240.......250........260-....--------.....270.-......280-.........290.....--..300.......310.-.....----
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METVPKKRDA
P
V
L
TAG-K
G
I
S
W
M
A
A
LKRD
K
W
L
Y
L
L
L
I
P
G
----------
L
L
Y
F
L
I
F
K
Y
L
P
-
M
-
W
G
V
L
I
A
FKDYS----
P
Y
LGF
W
K
S
EWV
G
F
D
Y
F
K
D
----
F
FMN-----------
P
--
D
----
F
F
R
L
L
R
N
T
L
M
L
A
S
L
D
L
-----
L
F
AF
P
A
P
L
I
-----
L
A
L
L
L
N
E
V
R
K
A
V
Y
K
R
C
I
Q
T
F
I
YVPHF
V
S
W
T
I
V
V
S
I
T
F
--
V
F
F
T
V
D
T
G
V
I
N
K
L
I
M
S
LTG
E
Q
I
---
S
FLSD
A
D
W
F
-
R
P
M
I
V
M
Q
S
I
W
K
ETG
W
G
T
I
L
F
L
A
A
L
A
TV
D
Q
-----------------
E
Q
Y
E
A
A
I
MDGA----G
R
F
R
R
M
W
H
I
T
L
P
A
I
R
S
T
I
I
V
L
-------
L
I
L
R
I
G
S
F
L
N
L
-
G
F
E
Q
V
Y
L
M
T
N---SLN
R
--------
S
V
A
D
I
F
D
T
Y
-
V
Y
M
M
GIT---QGAY
S
Y
S
T
A
V
G
L
F
K
S
V
V
--
G
I
I
L
IFG
A
N
Y
I
A
K
K
F
D-QEGLF----
3
PsiBlast_PDB
82.74
40%
-175
- C4 -
4XIG
-
?
M:
[8-300]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
K
R
D
W
L
L
Y
A
M
L
L
P
T
----------
I
I
W
F
L
I
F
L
Y
K
P
-
M
-
I
G
L
Q
M
A
F
K
Q
Y
---------------
I
G
F
D
H
F
V
T
----
L
F
Q
S
-----------
E
--
Q
----
F
I
R
A
I
K
N
T
L
T
L
S
G
L
S
L
-----
L
F
G
F
P
M
P
I
L
-----
L
A
L
M
I
N
E
V
Y
S
K
G
Y
R
K
A
V
Q
T
I
V
Y
L
P
H
F
I
S
I
V
I
V
A
G
L
V
V
--
T
F
L
S
P
S
T
G
V
V
N
N
M
L
S
W
I
G
L
D
R
V
---
Y
F
L
T
Q
P
E
W
F
-
R
P
I
Y
I
S
S
N
I
W
K
E
A
G
F
D
S
I
V
Y
L
A
A
I
M
S
I
N
P
-----------------
A
L
Y
E
S
A
Q
V
D
G
A
----
T
R
W
Q
M
I
T
R
I
T
L
P
C
I
V
P
T
I
A
V
L
-------
L
V
I
R
L
G
H
I
L
E
V
-
G
F
E
Y
I
I
L
L
Y
Q
---
P
T
T
Y
--------
E
T
A
D
V
I
S
T
Y
-
I
Y
R
L
G
L
Q
---
G
A
R
Y
D
I
A
T
A
A
G
I
F
N
A
V
V
--
A
L
V
I
V
L
F
A
N
H
M
S
R
R
I
T
-
K
T
G
V
-----
4
PsiBlast_PDB
81.89
40%
-172
- C4 -
4XTC
-
?
M:
[8-300]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
K
R
D
W
L
L
Y
A
M
L
L
P
T
----------
I
I
W
F
L
I
F
L
Y
K
P
-
M
-
I
G
L
Q
M
A
F
K
Q
Y
---------------
I
G
F
D
H
F
V
T
----
L
F
Q
S
-----------
E
--
Q
----
F
I
R
A
I
K
N
T
L
T
L
S
G
L
S
L
-----
L
F
G
F
P
M
P
I
L
-----
L
A
L
M
I
N
E
V
Y
S
K
G
Y
R
K
A
V
Q
T
I
V
Y
L
P
H
F
I
S
I
V
I
V
A
G
L
V
V
--
T
F
L
S
P
S
T
G
V
V
N
N
M
L
S
W
I
G
L
D
R
V
---
Y
F
L
T
Q
P
E
W
F
-
R
P
I
Y
I
S
S
N
I
W
K
E
A
G
F
D
S
I
V
Y
L
A
A
I
M
S
I
N
P
-----------------
A
L
Y
E
S
A
Q
V
D
G
A
----
T
R
W
Q
M
I
T
R
I
T
L
P
C
I
V
P
T
I
A
V
L
-------
L
V
I
R
L
G
H
I
L
E
V
-
G
F
E
Y
I
I
L
L
Y
Q
---
P
T
T
Y
--------
E
T
A
D
V
I
S
T
Y
-
I
Y
R
L
G
L
Q
---
G
A
R
Y
D
I
A
T
A
A
G
I
F
N
A
V
V
--
A
L
V
I
V
L
F
A
N
H
M
S
R
R
I
T
-
K
T
G
V
-----
2
PsiBlast_PDB
80.28
40%
-168
- C4 -
4TQV
-
?
A:
[31-320]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
K
R
D
W
L
L
Y
A
M
L
L
P
T
----------
I
I
W
F
L
I
F
L
Y
K
P
-
M
-
I
G
L
Q
M
A
F
K
Q
--------------
P
W
I
G
F
D
H
F
V
T
----
L
F
Q
S
-----------
E
--
Q
----
F
I
R
A
I
K
N
T
L
T
L
S
G
L
S
L
-----
L
F
G
F
P
M
P
I
L
-----
L
A
L
M
I
N
E
V
Y
S
K
G
Y
R
K
A
V
Q
T
I
V
Y
L
P
H
F
I
S
I
V
I
V
A
G
L
V
V
--
T
F
L
S
P
S
T
G
V
V
N
N
M
L
S
W
I
G
L
D
R
V
---
Y
F
L
T
Q
P
E
W
F
-
R
P
I
Y
I
S
S
N
I
W
K
E
A
G
F
D
S
I
V
Y
L
A
A
I
M
S
I
N
P
-----------------
A
L
Y
E
S
A
Q
V
D
G
A
----
T
R
W
Q
M
I
T
R
I
T
L
P
C
I
V
P
T
I
A
V
L
-------
L
V
I
R
L
G
H
I
L
E
V
-
G
F
E
Y
I
I
L
L
Y
Q
---
P
T
T
Y
--------
E
T
A
D
V
I
S
T
Y
-
I
Y
R
L
G
L
Q
---
G
A
R
Y
D
I
A
T
A
A
G
I
F
N
A
V
V
--
A
L
V
I
V
L
F
A
N
H
M
S
R
R
I
T
-
K
--------
1
PsiBlast_PDB
80.01
40%
-180
- C4 -
4TQU
-
?
M:
[8-297]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
K
R
D
W
L
L
Y
A
M
L
L
P
T
----------
I
I
W
F
L
I
F
L
Y
K
P
-
M
-
I
G
L
Q
M
A
F
----------------
P
W
I
G
F
D
H
F
V
T
----
L
F
Q
S
-----------
E
--
Q
----
F
I
R
A
I
K
N
T
L
T
L
S
G
L
S
L
-----
L
F
G
F
P
M
P
I
L
-----
L
A
L
M
I
N
E
V
Y
S
K
G
Y
R
K
A
V
Q
T
I
V
Y
L
P
H
F
I
S
I
V
I
V
A
G
L
V
V
--
T
F
L
S
P
S
T
G
V
V
N
N
M
L
S
W
I
G
L
D
R
V
---
Y
F
L
T
Q
P
E
W
F
-
R
P
I
Y
I
S
S
N
I
W
K
E
A
G
F
D
S
I
V
Y
L
A
A
I
M
S
I
N
P
-----------------
A
L
Y
E
S
A
Q
V
D
G
A
----
T
R
W
Q
M
I
T
R
I
T
L
P
C
I
V
P
T
I
A
V
L
-------
L
V
I
R
L
G
H
I
L
E
V
-
G
F
E
Y
I
I
L
L
Y
Q
---
P
T
T
Y
--------
E
T
A
D
V
I
S
T
Y
-
I
Y
R
L
G
L
Q
---
G
A
R
Y
D
I
A
T
A
A
G
I
F
N
A
V
V
--
A
L
V
I
V
L
F
A
N
H
M
S
R
R
I
T
-
K
--------
19
HHSearch
79.80
40%
-178
- C4 -
4TQU
-
?
M:
[6-297]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
D
I
K
R
D
W
L
L
Y
A
M
L
L
P
T
----------
I
I
W
F
L
I
F
L
Y
K
P
-
M
-
I
G
L
Q
M
A
F
----------------
P
W
I
G
F
D
H
F
V
T
----
L
F
Q
S
-----------
E
--
Q
----
F
I
R
A
I
K
N
T
L
T
L
S
G
L
S
L
-----
L
F
G
F
P
M
P
I
L
-----
L
A
L
M
I
N
E
V
Y
S
K
G
Y
R
K
A
V
Q
T
I
V
Y
L
P
H
F
I
S
I
V
I
V
A
G
L
V
V
--
T
F
L
S
P
S
T
G
V
V
N
N
M
L
S
W
I
G
L
D
R
V
---
Y
F
L
T
Q
P
E
W
F
-
R
P
I
Y
I
S
S
N
I
W
K
E
A
G
F
D
S
I
V
Y
L
A
A
I
M
S
I
N
P
-----------------
A
L
Y
E
S
A
Q
V
D
G
A
----
T
R
W
Q
M
I
T
R
I
T
L
P
C
I
V
P
T
I
A
V
L
-------
L
V
I
R
L
G
H
I
L
-
E
V
G
F
E
Y
I
I
L
L
Y
Q
---
P
T
T
Y
--------
E
T
A
D
V
I
S
T
Y
-
I
Y
R
L
G
L
Q
---
G
A
R
Y
D
I
A
T
A
A
G
I
F
N
A
V
V
--
A
L
V
I
V
L
F
A
N
H
M
S
R
R
I
T
-
K
--------
22
HHSearch
60.24
21%
-177
* C4 *
3RLF
2
MALF_ECOLI
F:
[257-503]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
T
G
W
K
N
F
T
R
----
V
F
T
D
-----------
E
--
G
IQKP
F
L
A
I
F
V
W
T
V
V
F
S
L
I
T
V
-----
F
L
T
V
A
V
G
M
V
-----
L
A
C
L
V
Q
W
E
A
L
-
R
G
K
A
V
Y
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
F
K
--
G
L
F
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Q
S
F
G
E
I
N
M
M
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S
A
L
F
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V
K
P
---
A
W
F
S
D
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T
T
A
-
R
T
M
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I
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T
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L
G
Y
P
Y
M
M
I
L
C
M
G
L
L
K
A
I
P
D
-----------------
D
L
Y
E
A
S
A
M
D
G
A
----
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
-------
M
I
A
S
F
A
F
N
F
-
N
-
N
F
V
L
I
Q
L
L
T
N
---
G
G
P
D
RLGTTTPA
G
Y
T
D
L
L
V
N
Y
-
T
Y
R
I
A
F
E
GGG
G
Q
D
F
G
L
A
A
A
I
A
T
L
I
F
L
L
--
V
G
A
L
A
I
--------------------
30
Fugue
55.90
18%
-157
- C4 -
2R6G
1
MALF_ECOLI
F:
[13-504]
DALKWSVLGLLGLLVGYLVVLMYAQGEYLFAITTLILSSAGLYIFANRKAYAWRYVYPGMAGMGLFVLFPLVCTIAIAFTNYSSTNQLTFERAQEVLLDRSWQAGKTYNFGLYPAGDEWQLALSDGETGKNYLSDAFKFGGEQKLQLKETTAQPEGERANLRVITQNRQALSDI
T
A
I
L
P
D
G
N
K
V
M
M
S
S
L
R
-
Q
F
S
G
T
Q
P
L
Y
T
L
D
G
D
G
T
L
T
N
N
Q
S
----------
G
V
K
Y
R
P
N
N
Q
I
G
F
Y
-
Q
S
I
T
A
N
W
G
D
E
K
----
L
S
P
G
--
Y
T
V
T
T
G
W
K
N
F
T
R
----
V
F
T
D
-----------
E
--
G
IQKP
F
L
A
I
F
V
W
T
V
V
F
S
L
I
T
V
-----
F
L
T
V
A
V
G
M
V
-----
L
A
C
L
V
Q
W
-
E
A
L
R
G
K
A
V
Y
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
F
K
--
G
L
F
N
Q
S
F
G
E
I
N
M
M
L
S
A
L
F
G
V
K
P
---
A
W
F
S
D
P
T
T
A
-
R
T
M
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
C
M
G
L
L
K
A
I
P
D
-----------------
D
L
Y
E
A
S
A
M
D
G
A
----
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
-------
M
I
A
S
F
A
F
N
F
N
N
--
F
V
L
I
Q
L
L
T
N
GGP
D
R
L
G
--------
T
T
T
P
A
G
Y
T
D
-
L
L
V
N
Y
T
Y
---
R
I
A
F
E
G
G
G
G
Q
D
F
G
L
A
A
A
--
I
A
T
L
I
F
L
L
V
G
A
L
A
I
V
-----------
23
HHSearch
53.70
15%
-183
- C4 -
3RLF
4
MALG_ECOLI
G:
[11-281]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
L
F
I
T
H
L
L
----------
L
L
L
F
I
A
A
I
M
F
P
-
L
L
M
V
V
A
I
S
L
R
Q
G
N
----
F
A
T
G
S
L
I
P
E
Q
I
S
W
D
H
W
K
L
----
A
L
G
F
SVEQADGRITP
P
PF
P
----
V
L
L
W
L
W
N
S
V
K
V
A
G
I
S
A
-----
I
G
I
V
A
L
S
T
T
-----
C
A
Y
A
F
A
R
M
R
F
-
P
G
K
A
T
L
L
K
G
M
L
I
F
Q
M
F
P
A
V
L
S
L
V
A
L
Y
--
A
L
F
D
R
-
L
G
E
Y
I
P
F
I
---
G
---------
L
N
----
T
-
H
G
G
V
I
F
A
Y
L
G
-
G
I
A
L
H
V
W
T
I
K
G
Y
F
E
T
I
D
S
-----------------
S
L
E
E
A
A
A
L
D
G
A
----
T
P
W
Q
A
F
R
L
V
L
L
P
L
S
V
P
I
L
A
V
V
-------
F
I
L
S
F
I
A
A
I
-
T
-
E
V
P
V
A
S
L
L
L
R
---
D
V
-----------
N
S
Y
T
L
A
V
G
-
M
Q
Q
Y
L
N
P
Q--
N
Y
L
W
G
D
F
A
A
A
A
V
M
S
A
L
P
--
I
T
I
V
F
L
L
A
------------------
37
Fugue
53.05
19%
-153
- C5 -
4GF7
8
?
A:
[10-379]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
T
R
R
A
E
V
A
G
G
G
F
A
G
L
T
A
A
I
A
L
K
Q
N
G
W
D
V
R
L
H
E
K
S
S
E
L
R
A
F
GA
G
I
Y
L
W
H
N
G
L
R
V
L
E
-
G
-
L
G
A
L
D
D
V
L
Q
G
S
H
T
P
P
T
Y
E
T
W
M
H
N
K
S
V
S
K
E
T
F
N
G
L
P
W
R
I
M
T
R
-----------
S
--
H
----
L
H
D
A
L
V
N
R
A
R
A
L
G
V
D
I
-----
S
V
N
S
E
A
V
A
A
D
PV
G
R
L
T
L
Q
T
G
E
V
L
E
A
-------
D
L
I
V
G
A
D
G
V
G
S
K
V
R
D
S
I
G
F
K
Q
D
R
W
V
S
K
D
G
L
I
-
R
L
I
V
P
R
M
K
K
E
L
GHG
E
W
D
N
T
I
D
M
W
-
N
F
W
P
R
V
Q
R
I
L
Y
S
P
C
N
E
N
E
L
Y
L
G
L
M
A
P
A
A
D
PRGSSVPID
L
E
V
W
V
E
M
F
P
F
L
E
P
C
L
I
E
A
A
K
LKT
A
R
Y
D
K
Y
E
T
T
K
L
D
S
W
T
R
G
K
V
A
L
V
G
DAA
H
A
M
C
P
A
L
A
Q
G
A
G
C
-
A
M
V
N
A
F
S
L
S
Q
---
D
L
E
E
GS------
S
V
E
D
A
L
V
A
W
E
T
R
I
R
P
I
T
---
D
R
C
Q
A
L
S
G
D
Y
A
A
N
R
S
L
S
--
K
G
N
M
F
T
P
A
A
L
E
A
A
R
Y
D
P
L
R
R
V
Y
SWPQ
35
Fugue
52.49
19%
-152
* C5 *
4H2Q
7
?
A:
[10-379]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
T
R
R
A
E
V
A
G
G
G
F
A
G
L
T
A
A
I
A
L
K
Q
N
G
W
D
V
R
L
H
E
K
S
SELRAFGA
G
I
Y
L
W
H
N
G
L
R
V
L
E
-
G
-
L
G
A
L
D
D
V
L
Q
G
S
H
T
P
P
T
Y
E
T
W
M
H
N
K
S
V
S
K
E
T
F
N
G
L
P
W
R
I
M
T
R
-----------
S
--
H
----
L
H
D
A
L
V
N
R
A
R
A
L
G
V
D
I
S
V
NSE
A
V
A
A
D
P
V
G
R
-----
L
T
L
Q
T
G
E
V
L
E
A
-------
D
L
I
V
G
A
D
G
V
G
S
K
V
R
D
S
I
G
F
K
Q
D
R
W
V
S
K
D
G
L
I
-
R
L
I
V
P
R
M
K
K
E
L
GHG
E
W
D
N
T
I
D
M
W
-
N
F
W
P
R
V
Q
R
I
L
Y
S
P
C
N
E
N
E
L
Y
L
G
L
M
A
P
A
A
D
PRGSSVPID
L
E
V
W
V
E
M
F
P
F
L
E
P
C
L
I
E
A
A
K
LKT
A
R
Y
D
K
Y
E
T
T
K
L
D
S
W
T
R
G
K
V
A
L
V
G
DAA
H
A
M
C
P
A
L
A
Q
G
A
G
C
-
A
M
V
N
A
F
S
L
S
Q
---
D
L
E
E
GS------
S
V
E
D
A
L
V
A
W
E
T
R
I
R
P
I
T
---
D
R
C
Q
A
L
S
G
D
Y
A
A
N
R
S
L
S
--
K
G
N
M
F
T
P
A
A
L
E
A
A
R
Y
D
P
L
R
R
V
Y
SWPQ
20
HHSearch
51.57
18%
-174
- C4 -
2ONK
-
WTPB_ARCFU
C:
[24-275]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
R
L
L
F
S
A
L
L
A
L
L
----------
S
S
I
I
L
L
F
V
L
L
P
-
V
A
A
T
V
T
L
Q
L
------------------
F
N
F
D
E
F
L
K
----
A
A
S
D
-----------
P
--
A
----
V
W
K
V
V
L
T
T
Y
Y
A
A
L
I
S
T
-----
L
I
A
V
I
F
G
T
P
-----
L
A
Y
I
L
A
R
K
S
F
-
P
G
K
S
V
V
E
G
I
V
D
L
P
V
V
I
P
H
T
V
A
G
I
A
L
L
--
V
V
F
G
S
-
S
G
L
I
G
S
F
S
P
------
L
---
K
F
V
----
D
A
-
L
P
G
I
V
V
A
M
L
F
V
S
V
P
I
Y
I
N
Q
A
K
E
G
F
A
S
V
D
V
-----------------
R
L
E
H
V
A
R
T
L
G
S
----
S
P
L
R
V
F
F
T
V
S
L
P
L
S
V
R
H
I
V
A
G
-------
A
I
M
S
W
A
R
G
I
-
S
-
E
F
G
A
V
V
V
I
A
Y
---
Y
-------------
P
M
I
A
P
T
L
-
I
Y
E
R
Y
L
----
S
E
G
L
S
A
A
M
P
V
A
A
I
L
I
L
L
--
S
L
A
V
F
V
A
L
R
I
I
V
G
-------------
33
Fugue
51.39
13%
-165
- C4 -
4TQU
-
?
N:
[2-284]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
T
P
F
-
Y
S
R
S
D
R
I
F
G
I
V
N
A
V
L
L
G
I
F
A
L
C
----------
A
L
Y
P
I
I
Y
I
F
S
M
-
S
-
I
S
S
G
A
A
V
--
T
Q
----
G
R
V
F
L
L
P
V
D
I
-
D
F
S
A
Y
G
R
----
V
L
H
D
-----------
K
--
L
----
F
W
T
S
Y
A
N
T
I
F
Y
T
V
F
G
V
-----
V
T
S
L
I
F
I
V
P
-----
G
A
Y
A
L
S
K
P
R
I
R
G
R
R
V
F
G
F
I
I
A
F
T
M
W
F
------------------
N
A
G
M
I
P
F
F
L
N
M
R
D
L
G
L
L
---
D
----------
N
R
F
G
I
L
I
G
F
A
C
N
A
F
N
I
I
L
M
R
N
Y
F
E
S
I
S
A
-----------------
S
F
E
E
A
A
R
M
D
G
A
----
N
D
L
Q
I
L
W
K
V
Y
I
P
L
A
K
P
A
L
A
T
I
-------
T
L
L
C
A
I
S
R
W
N
G
-
Y
F
W
A
M
V
L
L
R
A
---
E
E
K
I
--------
P
L
Q
V
Y
L
K
K
T
-
I
V
D
L
N
V
N
---
E
E
F
A
G
A
L
L
T
N
S
Y
S
M
E
T
V
VG
A
I
I
V
M
S
I
I
P
V
I
I
V
Y
P
V
-
V
Q
K
Y
F
TK--
31
Fugue
50.40
16%
-154
- C4 -
2ONK
-
WTPB_ARCFU
C:
[24-275]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
R
L
L
F
S
A
L
L
A
L
L
----------
S
S
I
I
L
L
F
V
L
L
P
-
V
-
A
A
T
V
T
L
Q
L
F
-----------------
N
F
D
E
F
L
K
----
A
A
S
D
-----------
P
--
A
----
V
W
K
V
V
L
T
T
Y
Y
A
A
L
I
S
T
-----
L
I
A
V
I
F
G
T
P
-----
L
A
Y
I
L
A
R
K
S
F
P
G
-
K
S
V
V
E
G
I
V
D
L
P
V
V
I
P
--------------
H
T
V
A
G
I
A
L
L
V
V
F
G
S
S
G
L
I
G
---
S
F
S
P
L
K
F
V
D
A
L
P
G
I
V
V
A
M
L
F
V
S
V
P
I
Y
I
N
Q
A
K
E
G
F
A
S
V
D
V
-----------------
R
L
E
H
V
A
R
T
L
G
S
----
S
P
L
R
V
F
F
T
V
S
L
P
L
S
V
R
H
I
V
A
G
-------
A
I
M
S
W
A
R
G
I
S
----
E
F
G
A
V
V
V
I
---
A
Y
Y
P
--------
M
I
A
P
T
L
I
Y
E
-
R
Y
L
S
E
-------
G
L
S
A
A
M
P
V
A
A
I
L
I
L
L
--
S
L
A
V
F
V
A
L
R
I
I
V
G
-------------
21
HHSearch
48.84
18%
-158
- C4 -
3D31
-
?
C:
[67-283]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
S
G
L
V
K
----
A
A
G
N
-----------
R
--
S
----
V
I
S
S
I
F
L
S
L
Y
A
G
F
L
A
T
-----
L
L
A
L
L
L
G
A
P
-----
T
G
Y
I
L
A
R
F
D
F
-
P
G
K
R
L
V
E
S
I
I
D
V
P
V
V
V
P
H
T
V
A
G
I
A
L
L
--
T
V
F
G
S
-
R
G
L
I
G
E
P
L
E
S
Y
----
I
---
Q
F
----
R
D
A
-
L
P
G
I
V
V
A
M
L
F
V
S
M
P
Y
L
A
N
S
A
R
E
G
F
K
S
V
D
P
-----------------
R
L
E
N
A
A
R
S
L
G
A
----
P
L
W
K
A
F
F
F
V
T
L
P
L
S
A
R
Y
L
L
I
G
-------
S
V
M
T
W
A
R
A
I
-
S
-
E
F
G
A
V
V
I
L
A
Y
---
Y
-------------
P
M
V
G
P
T
L
-
I
Y
D
R
F
I
----
S
Y
G
L
S
A
S
R
P
I
A
V
L
L
I
L
V
--
T
L
S
I
F
L
V
I
R
-----------------
13
PsiBlast_PDB
48.78
30%
-173
- C4 -
3RLF
2
MALF_ECOLI
F:
[314-450]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
A
V
Y
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
F
K
G
L
------
F
N
Q
S
F
G
E
I
N
M
M
L
S
A
L
F
G
V
K
P
---
A
W
F
S
D
P
T
T
A
-
R
T
M
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
C
M
G
L
L
K
A
I
P
D
-----------------
D
L
Y
E
A
S
A
M
D
G
A
----
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
-------
M
I
A
S
F
A
F
N
F
N
--
N
F
V
L
I
Q
L
L
T
N
---
G
----------------------------------------------------------------------------
7
PsiBlast_PDB
48.41
30%
-181
- C4 -
3PUY
2
MALF_ECOLI
F:
[314-450]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
A
V
Y
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
F
K
G
L
------
F
N
Q
S
F
G
E
I
N
M
M
L
S
A
L
F
G
V
K
P
---
A
W
F
S
D
P
T
T
A
-
R
T
M
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
C
M
G
L
L
K
A
I
P
D
-----------------
D
L
Y
E
A
S
A
M
D
G
A
----
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
-------
M
I
A
S
F
A
F
N
F
N
--
N
F
V
L
I
Q
L
L
T
N
---
G
----------------------------------------------------------------------------
12
PsiBlast_PDB
48.34
30%
-179
- C4 -
3PUX
3
MALF_ECOLI
F:
[314-450]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
A
V
Y
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
F
K
G
L
------
F
N
Q
S
F
G
E
I
N
M
M
L
S
A
L
F
G
V
K
P
---
A
W
F
S
D
P
T
T
A
-
R
T
M
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
C
M
G
L
L
K
A
I
P
D
-----------------
D
L
Y
E
A
S
A
M
D
G
A
----
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
-------
M
I
A
S
F
A
F
N
F
N
--
N
F
V
L
I
Q
L
L
T
N
---
G
----------------------------------------------------------------------------
14
PsiBlast_PDB
48.08
30%
-172
- C4 -
4JBW
1
MALF_ECOLI
F:
[314-450]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
A
V
Y
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
F
K
G
L
------
F
N
Q
S
F
G
E
I
N
M
M
L
S
A
L
F
G
V
K
P
---
A
W
F
S
D
P
T
T
A
-
R
T
M
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
C
M
G
L
L
K
A
I
P
D
-----------------
D
L
Y
E
A
S
A
M
D
G
A
----
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
-------
M
I
A
S
F
A
F
N
F
N
--
N
F
V
L
I
Q
L
L
T
N
---
G
----------------------------------------------------------------------------
16
PsiBlast_PDB
47.74
30%
-173
- C4 -
4KI0
5
MALF_ECOLI
F:
[314-450]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
A
V
Y
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
F
K
G
L
------
F
N
Q
S
F
G
E
I
N
M
M
L
S
A
L
F
G
V
K
P
---
A
W
F
S
D
P
T
T
A
-
R
T
M
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
C
M
G
L
L
K
A
I
P
D
-----------------
D
L
Y
E
A
S
A
M
D
G
A
----
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
-------
M
I
A
S
F
A
F
N
F
N
--
N
F
V
L
I
Q
L
L
T
N
---
G
----------------------------------------------------------------------------
10
PsiBlast_PDB
47.62
30%
-173
- C4 -
3PUV
3
MALF_ECOLI
F:
[314-450]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
A
V
Y
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
F
K
G
L
------
F
N
Q
S
F
G
E
I
N
M
M
L
S
A
L
F
G
V
K
P
---
A
W
F
S
D
P
T
T
A
-
R
T
M
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
C
M
G
L
L
K
A
I
P
D
-----------------
D
L
Y
E
A
S
A
M
D
G
A
----
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
-------
M
I
A
S
F
A
F
N
F
N
--
N
F
V
L
I
Q
L
L
T
N
---
G
----------------------------------------------------------------------------