@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu07300: (2016-06-11 )
MKASVIIPAYNSKERLYNSLLSLNQQECDEEFEVIVADNGSEDGTLSMLESFQADFPLIFTRIKENRGIAYGRNQALRNARGDILIFHDSDMLAAKDLVAKHIKAHENEENLVVCGLFWKRIYSFYYERFEEEHKEQLAKLTGEMPKKDKQKLLEEADIKNGSFLDKSFDLDTDFIDVLKKILDEYGDDLKGYHMPWRFFITNNSSVKRKHVVDLGLFDEGIVRYGFEDYDLGIRLHQAGLTFRLRRDIVSVHQEHPSNCKSVDDIRANIAYMCDKYNNIRSLDVHLAFNGPFPPDMTNRIMADIQKLLESQKYDMLLNLFLELLHVVKERNIDPDWRKKSPRVTAKSFDLQTVRKLLPKAKKKLGVNDFANALYALVNDLLHVDLRSLDVV
Atome Classification :
(20 SA)
----------------------------------------------------------------------------------.........10-..---.-.....20........30-.--........40..--.------.-----.--...50.----------..--.--..---..60.--------.----------------------.-------.-..-..70........80---.........90...-.....100--...-......-110-.......120........130.....----..140.......----150..--.....160....-..-.170........180---.----..---.-...190---.........200-----.----------........210-------....-...220.......230.....-..240-.......250......-.260----------------------------.-----......270....-----------...280------.......290.......300...--------....310---------.......320.------......330.......340...-------...---------.350.....----------..360.....----..370.......380.......390-----------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------------------------------------------------MK
A
S
V
I
I
PAYN-
S
K
---
E
-
R
L
Y
N
S
L
L
SL
N
Q
Q
E
C
D
E--E--
F
E
V
I
V
ADNGSED--
G
------
T
-----
L
--
S
M
L
E
S
F
----------QA--D--F
P
---
L
I
F
T
R
--------I----------------------K-------E-NR-GIAYGR
N
Q
A
L
R
NA----RG
D
I
L
I
F
HDS
D
M
L
A
-
A
K
D
L
V
A
----
K
H
I
-
K
AHENE-E
N
L
-
V
V
C
G
L
F
W
K
-
R
I
Y
S
F
Y
Y
E
R
F
E
E
E
H
K
E
Q
----
L
A
K
L
T
GEMP
K
K
D
----
K
Q
K
L
L
--
E
E
ADIKNGSFLD-KS-FDL-
D
T
D
F
I
D
V
L
K
K
I
---
L
----
D
E---Y-GDDL-----KGYHM
P
W
R
F
F
-------
I
----------TNNSSV
K
R
K
H
V
-------
V
DLG-L
F
D
E
G
I
V
RYGFEDYD
L
G
I
R
L
H
-QAG
L
T
-
F
R
L
R
R
D
I
V
S
V
H
Q
EHPS-NCK
S
----------------------------
V
-----
D
D
I
R
A
N
I
A
Y
M
CDK-----------YNN
I
R
S
------
L
D
V
H
L
A
FNGPFPP
D
M
T
N
R
I
M
A
D
I
--------
Q
K
L
L
E
SQ---------
K
Y
D
M
L
L
N
L
F
L
E
------
L
L
H
V
V
K
ERNID
P
D
WRKKSPRVT-------AKS---------F
D
L
Q
T
V
R
K
L
----------
L
P
K
A
K
K
KLG
V
----
N
D
F
A
N
A
L
Y
A
L
V
N
D
L
L
H
V
D
L
R
SLDVV-----------------------------------------------------------------------------------------------
23
Fugue
71.25
19%
-88
- C2 -
2Z86
4
CHS_ECOLX
A:
[4-625]
IDID
A
A
T
K
I
M
C
S
N
A
KA
I
S
L
N
E
V
E
K
N
E
I
I
S
K
Y
R
E
I
T
A
K
K
S
E
R
A
E
L
K
EVEPIPLDWPSDLTLPPLPESTND
Y
V
W
A
G
K
RKELLII
D
G
L
S
I
V
I
P
T
Y
N
-
R
A
---
K
-
I
L
A
I
T
L
A
C
L
C
N
Q
K
T
I
Y
--
D
--
Y
E
V
I
V
A
D
D
G
S
K
E
--
N
------
I
-----
E
--
E
I
V
R
E
F
----------
E
S
--
L
--
L
N
---
I
K
Y
V
R
--------
Q
----------------------
K
-------
D
Y
G
Y
-
Q
L
C
A
V
R
N
L
G
L
R
A
A
----
K
Y
N
Y
V
A
I
L
D
C
D
M
A
P
-
N
P
L
W
V
Q
----
S
Y
M
-
E
L
L
A
V
D
-
D
N
V
-
A
L
I
--------
G
P
R
K
Y
I
D
T
S
K
H
T
Y
L
D
----
F
L
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Q
K
S
L
I
N
E
I
P
----
E
S
V
D
W
--
R
I
E
H
F
K
N
T
D
N
L
R
-
L
C
-
N
------------------------------------------
T
P
F
R
F
F
-------
S
----------
G
G
N
V
A
F
A
K
K
W
L
-------
F
R
A
G
-
W
F
D
E
E
F
T
H
W
G
G
E
D
N
E
F
G
Y
R
L
Y
-
R
E
G
C
Y
-
F
R
S
V
E
G
A
M
A
Y
H
Q
E
P
P
Q
-
L
L
Q
Q
KVPYFYRKKEKIESATLKRVPL
V
S
I
Y
I
P
A
-----
Y
N
C
S
K
Y
I
V
R
C
V
E
S
-----------
A
L
N
Q
T
I
------
T
D
L
E
V
C
I
C
D
D
G
S
T
D
D
T
L
R
I
L
Q
E
H
YANHPR
V
R
F
I
S
Q
K
N
K
---------
G
I
G
S
A
S
N
T
A
V
R
L
CRGF
Y
I
G
Q
L
D
S
D
D
F
L
E
P
D
A
V
E
L
C
L
D
E
F
-------
R
K
D
---------
L
S
L
A
C
V
Y
T
T
----------
N
R
N
I
D
R
E
G
N
L
----
I
S
N
G
Y
N
W
P
I
Y
S
R
E
K
L
T
S
A
M
I
C
H
H
F
R
M
F
T
A
R
A
W
N
L
T
EGFNESISNA
V
D
Y
D
M
Y
L
K
L
S
E
V
G
P
F
K
H
I
NKIC
Y
N
R
V
L
HSI
K
K
L
D
I
Q
K
E
N
H
F
K
V
V
N
E
S
LSRLGIKKYKYSPLTNLNECR
K
Y
T
W
E
K
I
35
HHSearch
64.65
18%
-87
* C2 *
2D7I
5
GLT10_HUMAN
A:
[112-373]
----------------------------------------------------------------------------------
P
N
T
S
I
I
I
P
F
H
N
-
E
G
W
--
S
-
S
L
L
R
T
V
H
S
V
L
N
R
S
P
P
E
L-
V
--
A
E
I
V
L
V
D
D
F
S
D
R
--
E
------
H
L----
K
--
K
P
L
E
D
Y
----------
M
A
L
-
F
--
P
S
---
V
R
I
L
R
--------
T
----------------------
K
-------
K
-
R
E
-
G
L
I
R
T
R
M
L
G
A
S
V
A
----
T
G
D
V
I
T
F
L
D
S
H
C
E
A
-
N
V
N
W
L
P
----
P
L
L
-
D
R
I
A
R
N
-
R
K
T
-
I
V
C
P
M
I
D
V
-
I
D
H
----
D
D
F
-------------
R
Y
-------------
E
T
Q
----
A
G
D
A
M
R
G
A
F
D
W
-
E
M
-
Y
------
Y
-
K
-
R
I
P
I
---
P
----
P
E
---
L
-
Q
K
A
D
-----
P
S
D
P
F
E
S
P
V
M
-------
A
----------
G
G
L
F
A
V
D
R
K
W
F
-------
W
E
L
G
-
G
Y
D
P
G
L
E
I
W
G
G
E
Q
Y
E
I
S
F
K
V
W
-
M
C
G
G
R
-
M
E
D
I
P
C
S
R
V
G
H
I
Y
R
K
Y
-
V
P
Y
K
----------------------------
V
P
A
G--
V
S
L
A
R
N
L
K
R
V
A
E
V
-----------
W
M
D
E
Y
A
------
E
Y
I
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
64.51
16%
-76
- C2 -
2D7I
6
GLT10_HUMAN
A:
[35-570]
-----GQKLKDWHD
K
E
A
I
R
R
D
A
Q
RVGNGEQGRPYPMTDAERVDQAYRENGFN
I
Y
V
S
D
K
ISLN
R
S
L
P
DIRH
P
N
C
N
S
KRYLE
T
L
P
N
T
S
I
I
I
P
F
H
N
E
G
W
---
S
-
S
L
L
R
T
V
H
S
V
L
N
R
S
P
P
E
L-
V
--
A
E
I
V
L
V
D
D
F
S
D
R
--
E
------
H
-----
L
K
K
P
L
E
D
Y
M
----------
A
L
--
F
--
P
S
---
V
R
I
L
R
--------
T
----------------------
K
-------
K
-
R
E
-
G
L
I
R
T
R
M
L
G
A
S
V
A
----
T
G
D
V
I
T
F
L
D
S
H
C
E
A
-
N
V
N
W
L
P
----
P
L
L
-
D
R
I
A
R
N
-
R
K
T
-
I
V
C
P
M
I
D
V
I
D
H
D
D
F
R
Y
E
T
Q
A
G
D
A
M
R
G
----
A
F
D
W
E
M
---
Y
Y
K
----
R
I
P
I
P
--
P
E
L
Q
K
A
D
P
S
D
P
F
-
E
S
-
P
V
M
-
A
G
G
L
F
A
V
D
R
K
W
---
F
----
W
E
L
GG
Y
-
D
P
G
L
EIWGG
E
Q
Y
E
I
S
F
K
V
W
-------
M
C
G
G
R
M
E
D
I
PC
S
R
V
G
H
I
Y
R
K
Y
V
P
Y
K
V
P
A
G
V
S
L
A
-
R
N
L
K
R
V
A
E
V
W
M
D
E
Y
A
E
Y
I
Y
Q
R
-
R
P
E
Y
R
-
H
L
S
A
G
D
V
A
V
Q
K
K
L
R
S
S
L
N
C
K
S
----------------------------
F
-----
K
W
F
M
T
K
I
A
W
D
L
P
K
FYPPVEPPAAA
W
G
E
I
R
N
VGTG
L
C
A
D
T
K
H
G
A
L
G
S
P
L
R
L
E
G
C
V
R
G
R
G
E
--------
A
A
W
N
N
M
Q
---------
V
F
T
F
T
W
R
E
D
I
R
------
P
G
D
P
Q
H
T
K
K
F
C
F
D
A
I
S
H
T
S
P
V
T
-------
L
Y
D
CHSMKGNQ
L
W
K
Y
R
K
D
K
T
L
YHPVSG
S
C
M
D
C
S
E
S
D
H
R
I
F
M
----
N
T
C
N
P
S
S
L
T
Q
Q
W
L
F
E
H
T
N
S
T
V
L
E
K
F
NRN--------------------------------------------------------------------------------------------
26
Fugue
59.43
16%
-114
- C2 -
5EKE
2
Y501_SYNY3
A:
[20-336]
----------------------------------------------------------------------------FQSNAT
I
E
L
S
I
V
I
P
M
Y
N
-
E
E
DN
L
E
-
H
L
F
A
R
L
L
E
V
L
T
P
L
-
K
I
--
T
--
Y
E
I
I
C
V
N
D
G
S
K
D
--
K
------
T
-----
L
--
K
Q
L
I
D
C
----------
Y
Q
--
S
--
N
R
Q--
I
K
I
V
N
--------
L
----------------------
S
-------
R
-
N
F
-
G
K
E
I
A
L
S
A
G
I
D
Y
A
----
Q
G
N
A
V
I
P
I
D
A
D
L
Q
D
-
P
P
E
L
I
H
----
E
L
V
-
D
K
W
R
E
G
-
Y
D
I
-
V
Y
A
T
R
----------------------------------------------------------------------------------------
R
---
S
-
R
Q
G
M
-----
T
E
I
K
I
P
------------------------------
P
N
T
-------
G
D
F
R
-
L
M
D
-----------------------------
R
K
V
V
N
A
I
K
Q
L
P
E
-
R
T
R
F
----------------------------
M
-----
K
G
L
F
A
W
V
G
Y
R
Q
T
F
-----------
V
L
F
D
R
N
------
Y
W
K
L
W
N
A
A
L
D
G
I
F
S
F
S
L
L
P
L
K
V
W
--------
T
Y
L
G
S
I
I
---------
S
L
L
S
L
A
Y
A
S
F
L
------
I
L
K
T
I
T
L
G
D
V
-
P
G
Y
A
S
L
M
V
A
I
L
-------
F
L
G
---------
G
V
Q
L
I
S
L
G
V
----------
I
G
E
Y
L
G
R
V
Y
E
----
E
V
K
A
R
P
L
Y
-
L
V
S
D
L
W
G
L
E
Y
L
P
---------------------------------------------------------------------------------------------------
33
HHSearch
59.23
18%
-103
- C2 -
1XHB
1
GALT1_MOUSE
A:
[29-294]
----------------------------------------------------------------------------------
P
T
T
S
V
V
I
V
F
H
N
-
E
A
W
--
S
-
T
L
L
R
T
V
H
S
V
I
N
R
S
P
R
H
M-
I
--
E
E
I
V
L
V
D
D
A
S
E
R
--
D
------
F
L----
K
--
R
P
L
E
S
Y
----------
V
K
--
K
LK
V
P
---
V
H
V
I
R
--------
M
----------------------
E
-------
Q
-
R
S
-
G
L
I
R
A
R
L
K
G
A
A
V
S
----
R
G
Q
V
I
T
F
L
D
A
H
C
E
C
-
T
A
G
W
L
E
----
P
L
L
-
A
R
I
K
H
D
-
R
R
T
-
V
V
C
P
I
I
D
V
-
I
S
D
----
D
T
F
--
E
Y
M
-------
A
G
S
---------------
D
M
--
T
-----
Y
G
G
F
N
W
K
L
N
-
F
R
-----
W
Y
P
V
P
Q
R
E
---
M
----
D
R
-----
R
K
G
D
-----
R
T
L
P
V
R
T
P
T
M
-------
A
----------
G
G
L
F
S
I
D
R
D
Y
F
-------
Q
E
I
G
-
T
Y
D
A
G
M
D
I
W
G
G
E
N
L
E
I
S
F
R
I
W
-
Q
C
G
G
T
-
L
E
I
V
T
C
S
H
V
G
H
V
F
-------------------------------------G----
Q
I
I
N
K
N
N
R
R
L
A
E
V
-----------
W
M
D
E
F
K
------
N
F
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
HHSearch
52.66
15%
-80
- C2 -
4FIX
2
GLFT2_MYCTU
A:
[180-446]
----------------------------------------------------------------------------------
A
N
I
A
V
G
I
P
T
F
N
-
R
P
---
A
-
D
C
V
N
A
L
R
E
L
T
A
D
P
L
V
D
Q
V
I
--
G
A
V
I
V
P
D
Q
G
E
R
K
VR
D
------
H
-----
P
--
D
F
P
A
A
A
----------
A
R
L
-
G
--
S
R
---
L
S
I
-
H
--------
D
----------------------
Q
-------
P
-
N
L
-
G
G
S
G
G
Y
S
R
V
M
Y
E
A
L
K
NT
D
C
Q
Q
I
L
F
M
D
D
D
I
R
L
-
E
P
D
S
I
L
----
R
V
L
-
A
M
H
R
F
A
-
K
A
P
-
M
L
V
G
G
Q
M
L
-
N
L
Q
-----
E
P
S
--
H
L
H
I
----
M
G
E
----------------
V
V
--
D
R
-----
S
I
F
M
W
-
T
A
-
A
P
-----
H
A
E
Y
D
H
D
F
AE-
Y
PLND
N
N
---
S
-
R
S
K
L
-----
L
H
R
R
I
D
V
D
Y
N
-------
G
----------
W
W
T
C
M
I
P
R
Q
V
A
-------
E
E
L
G
-
Q
P
L
P
L
F
I
--
K
W
D
D
A
D
Y
G
L
R
A
A
-
E
H
G
Y
P
-
T
V
T
L
P
G
A
A
I
W
H
M
A
W
S
D
-
K
D
D
A
ID
W
Q
------------------------
A
-----
Y
F
H
L
R
N
R
L
V
V
A
A
M
-----------
H
W
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
52.49
16%
-128
- C2 -
3BCV
-
?
A:
[5-218]
----------------------------------------------------------------------------------
P
K
V
S
V
I
V
P
I
Y
N
-
V
E
---
K
-
Y
L
D
Q
C
V
Q
A
L
L
A
Q
T
L
S
---
D
--
I
E
I
I
L
I
D
D
E
S
P
D
--
N
------
C
-----
P
--
K
I
C
D
D
Y
----------
A
A
Q
-
Y
--
P
N
---
I
K
V
I
H
-------------------------------
K
-------
K
-
N
A
-
G
L
G
M
A
C
N
S
G
L
D
V
A
----
T
G
E
Y
V
A
F
C
D
S
D
D
Y
V
-
D
S
D
M
Y
M
----
T
M
Y
-
N
V
A
Q
K
Y
-
T
C
D
-
A
V
F
T
----------------------------------------------------------
F
K
L
-
Y
K
-
N
-------
K
N
E
I
H
T
L
---
L
----
K
D
---
L
I
A
S
D
P
-----
Y
A
R
E
E
R
A
I
Q
V
-------
S
----------
A
K
V
V
L
Y
R
R
N
L
I
-------
E
K
K
H
L
R
F
V
S
E
R
I
-
L
P
S
E
D
L
I
F
N
V
D
V
L
-
A
N
S
N
I
-
V
C
V
L
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
52.04
13%
-76
- C2 -
1XHB
4
GALT1_MOUSE
A:
[8-466]
-------------------------------------------------------------N
R
S
L
P
DVRL
E
G
C
K
T
K
V
Y
P
D
NL
P
T
T
S
V
V
I
V
F
H
N
-
E
A
---
W
-
S
T
L
L
R
T
V
H
S
V
I
N
R
S
P
R
--
H
MI
E
E
I
V
L
V
D
D
A
S
E
R
--
D
------
F
-----
L
K-
R
P
L
E
S
Y
----------
V
K
--
K
--
L
K
V
P
-
V
H
V
I
R
--------
M
----------------------
E
-------
Q
-
R
S
-
G
L
I
R
A
R
L
K
G
A
A
V
S
----
R
G
Q
V
I
T
F
L
D
A
H
C
E
C
-
T
A
G
W
L
E
----
P
L
L
-
A
R
I
K
H
D
-
R
R
T
-
V
V
C
P
I
I
D
V
I
S
D
D
T
F
E
Y
M
A
G
S
D
M
T
Y
G
G
F
N
WK
L
N
F
R
W
Y
P
V
P
Q
R
E
----
M
D
R
R
K
GD
R
T
L
P
V
R
T
P
T
M
A
G
-
G
L
-
F
S
I
-
D
R
D
Y
F
Q
E
I
G
T
Y
DAG
M
----
D
I
---
W
-
G
G
-------
E
N
L
E
I
S
F
R
I
W
Q
C
G
G
T
L
E
I
----------
V
T
C
S
H
V
G
H
V
F
G
-------
Q
I
I
N
-
K
N
N
R
R
L
A
E
V
W
M
D
E
F
K
N
F
F
Y
I
I
-
S
P
G
V
T
-
K
V
D
Y
G
D
I
S
S
R
L
G
L
R
R
K
L
Q
C
K
P
----------------------------------------
F
S
W
Y
L
E
N
-----------
I
Y
P
D
S
Q
------
I
P
R
H
Y
F
S
L
G
E
I
R
N
V
E
T
N
Q
C
L
D
N
M
--------
A
R
K
E
N
E
K
V
G
I
F
NCHGM
G
G
N
Q
V
F
S
Y
T
A
N
------
K
E
I
R
T
D
D
L
C
L
D
V
S
K
L
N
G
P
V
T
M
L
KCHHLKG
N
Q
L
---------
W
E
Y
D
P
V
K
L
T
----------
L
Q
H
V
N
S
N
Q
C
L
D
K
A
T
E
E
D
S
Q
V
P
S
I
R
D
C
T
G
S
R
S
Q
Q
W
L
L
R
N
V
-----------------------------------------------------------------------------------------------
31
HHSearch
50.22
14%
-71
- C2 -
5AJO
12
GALT2_HUMAN
A:
[136-397]
----------------------------------------------------------------------------------
P
A
T
S
V
V
I
T
F
H
N
-
E
A
---
R
S
A
L
L
R
T
V
V
S
V
L
K
K
S
P
P
H
L-
I
--
K
E
I
I
L
V
D
D
Y
S
N
D
--
P
------
E
-----
D
--
G
A
L
L
G
K
----------
I
------
E
K
---
V
R
V
L
R
--------
N
----------------------
D
-------
R
-
R
E
-
G
L
M
R
S
R
V
R
G
A
D
A
A
----
Q
A
K
V
L
T
F
L
D
S
H
C
E
C
-
N
E
H
W
L
E
----
P
L
L
-
E
R
V
A
E
D
-
R
T
R
-
V
V
S
P
I
I
D
V
-
I
N
M
----
D
N
F
------------
Q
Y
V
------------
G
A
-
S
A
--
D
----
L
K
G
G
F
D
W
-
N
L
V
F
K
W
-----
D
Y
-
M
T
P
E
---
Q
----
R
R
---
S
-
R
Q
G
N
-----
P
V
A
P
I
K
T
P
M
I
-------
A
----------
G
G
L
F
V
M
D
K
F
Y
F
-------
E
E
L
G
-
K
Y
D
M
M
M
D
V
W
G
G
E
N
L
E
I
S
F
R
V
W
-
Q
C
G
G
S
-
L
E
I
I
P
C
S
R
V
G
H
V
F
R
K
Q
-
H
P
Y
T
----------------------------
F
PGG
S
G
T
V
F
A
R
N
T
R
R
A
A
E
V
-----------
W
M
D
E
Y
K
------
N
F
Y
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
HHSearch
50.18
14%
-97
- C2 -
4P02
-
?
A:
[141-375]
----------------------------------------------------------------------------------
P
T
V
D
I
L
V
P
S
Y
N
-
E
P
A
--
D
-
M
L
S
V
T
L
A
A
A
K
N
M
I
Y
P
A
R-
L
--
R
T
V
V
L
C
D
D
G
G
T
D
--
Q
------
R
C
M
SPD
P
--
E
L
A
Q
K
A
Q
E
R
R
R
E
L
Q
Q
L
C
R
--
E
--
L
G
---
V
V
Y
S
T
--------
R
----------------------
E
-------
R
-
N
E
H
A
K
A
G
N
M
S
A
A
L
E
R
L
----
K
G
E
L
V
V
V
F
D
A
D
H
V
P
-
S
R
D
F
L
A
----
R
T
V
-
G
Y
F
V
E
D
-
P
D
L
F
L
V
Q
T
P
H
F
F
-
I
N
P
-----
D
P
I
-----------
Q
R
N
----------------
L
--
A
L
----
G
D
R
C
P
P
--------------
E
N
E
M
F
---
Y
----
G
K
---
I
-
H
R
-------
G
L
D
R
W
G
G
A
F
F
-------
C
----------
G
S
A
A
V
L
R
R
R
A
L
-------
D
E
A
G
-
G
F
A
G
E
T
---
I
T
E
D
A
E
T
A
L
E
I
H
-
S
R
G
W
K
-
S
L
Y
I
D
R
A
M
I
A
G
L
Q
P
E
T
-
F
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
49.19
18%
-70
- C2 -
1QG8
2
SPSA_BACSU
A:
[1-255]
----------------------------------------------------------------------------------
P
K
V
S
V
I
M
T
S
Y
N
-
K
S
---
D
-
Y
V
A
K
S
I
S
S
I
L
S
Q
T
-
F
S
--
D
--
F
E
L
F
I
M
D
D
N
S
N
E
--
E
------
T
-----
L
--
N
V
I
R
P
F
----------
L
N
--
D
--
N
R
---
V
R
F
Y
Q
S
DISG
V
K
E
R
----------------------
T
-------
E
-
K
T
-
R
Y
A
A
L
I
N
Q
A
I
E
M
A
----
E
G
E
Y
I
T
Y
A
T
D
D
N
I
Y
-
M
P
D
R
L
L
----
K
M
V
-
R
E
L
D
T
H
-
P
E
K
-
A
V
I
Y
S
A
S
K
-
T
Y
H
L
N
D
I
V
K
E
T
V
R
P
A
A
Q
----
V
T
W
N
A
P
C
A
I
D
H
C
S
V
M
H
R
Y
S
V
L
--
E
K
V
K
E
K
F
G
S
Y
W
D
-
E
S
-
P
A
F
Y
R
I
G
D
A
R
F
F
W
R
V
---
N
----
H
F
---
Y
-
P
F
Y
P
-----
L
D
E
E
L
D
L
N
Y
I
-------
T
----------
E
F
V
R
N
L
P
P
Q
R
---------
N
C
R
-
E
L
R
E
S
L
K
K
L
G
M
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
48.72
18%
-111
- C2 -
3CKJ
5
GPGS_MYCPA
A:
[48-269]
----------------------------------------------------------------------------------
R
T
I
S
V
V
L
P
A
L
D
-
E
E
---
D
-
T
I
G
S
V
I
D
S
I
S
P
L
V
D
G
L
--
V
--
D
E
L
I
V
L
D
S
G
S
T
D
--
D
------
T
-----
E
--
I
R
A
V
A
A
------------------
G
---
A
R
V
V
S
--------
R
----------------------
E
QALPE
V
P
I
-
R
P
-
G
K
G
E
A
L
W
R
S
L
A
A
S
----
R
G
D
I
V
V
F
V
D
S
D
L
I
N
P
H
P
M
F
V
P
----
W
L
V
-
G
P
L
L
T
G
-
D
G
V
-
H
L
V
K
S
F
Y
R
-
R
P
-------------------------------------------------
G
R
V
T
-------------
E
L
V
A
R
P
L
---
L
----
A
A
--------
L
-----
R
P
E
L
G
C
I
L
Q
P
-------
L
----------
G
G
E
Y
A
A
T
R
E
L
L
-------
T
S
V
--
P
F
A
P
G
Y
----
G
V
E
I
G
L
L
V
D
T
F
D
R
L
G
L
D
A
I
A
Q
V
N
L
G
V
R
E
H
R
N
R
P
L
-
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
47.65
15%
-70
- C2 -
3CKJ
5
GPGS_MYCPA
A:
[15-329]
-------------------------------------------------GLRDTRPG
D
T
W
L
ADR
S
W
N
R
P
GWT
V
A
E
L
E
A
A
KAG
R
T
I
S
V
V
L
P
A
L
D
-
E
E
---
D
-
T
I
G
S
V
I
D
S
I
S
P
L
V
D
G
L
--
V
--
D
E
L
I
V
L
D
S
G
S
T
D
--
D
------
T
-----
E
--
I
R
A
V
A
A
----------
G
A
--
R
--
V
V
S
RE
Q
A
L
P
E
--------
V
----------------------
P
-------
I
-
R
P
-
G
K
G
E
A
L
W
R
S
L
A
A
S
----
R
G
D
I
V
V
F
V
D
S
D
L
I
N
P
H
P
M
F
V
P
----
W
L
V
-
G
P
L
L
T
G
-
D
G
V
-
H
L
V
K
S
F
Y
R
-
R
P
G
R
V
T
E
L
V
A
R
P
L
L
A
A
L
----
R
P
E
L
G
C
I
L
Q
P
L
G
----
G
E
Y
A
A
--
T
R
E
L
L
T
S
V
P
F
A
P
-
G
------
Y
G
V
E
I
G
L
L
V
D
T
---
F
----
D
R
---
L
-
G
---------------------------------------------------------------------------
L
D
A
I
A
-
Q
V
N
L
G
-
V
R
E
H
R
N
-----------------------------------------------------------------------------------------------
R
P
L
A
E
L
G
A
M
S
R
Q
V
--------
I
A
T
L
L
S
R
---------
C
G
I
P
D
S
G
V
G
L
T
------
Q
F
V
A
D
G
P
E
G
Q
S
Y
T
Q
H
T
W
P
V
S
L
A
-------
D
-----------------
R
P
P
----------
M
Q
A
I
R
P
R
-------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
46.44
30%
-144
- C2 -
3BCV
-
?
A:
[6-110]
-----------------------------------------------------------------------------------
K
V
S
V
I
V
P
I
Y
N
-
V
E
---
K
-
Y
L
D
Q
C
V
Q
A
L
L
A
Q
T
L
-
S
--
D
--
I
E
I
I
L
I
D
D
E
S
P
D
--
N
------
C
-----
P
--
K
I
C
D
D
Y
----------
A
A
--
Q
--
Y
P
---
N
I
K
V
I
--------
H
----------------------
K
-------
K
-
N
A
-
G
L
G
M
A
C
N
S
G
L
D
V
A
----
T
G
E
Y
V
A
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
44.58
25%
-111
- C2 -
1QGS
2
SPSA_BACSU
A:
[2-128]
-----------------------------------------------------------------------------------
K
V
S
V
I
M
T
S
Y
N
-
K
S
---
D
-
Y
V
A
K
S
I
S
S
I
L
S
Q
T
F
S
---
D
--
F
E
L
F
I
M
D
D
N
S
N
E
--
E
------
T
-----
L
--
N
V
I
R
P
F
LNDNR
V
R
F
Y
-
Q
S
--
D
--
I
S
---
G
V
K
E
R
--------
T
----------------------
E
-------
K
-
T
R
-
Y
A
A
L
I
-
N
Q
A
I
E
M
A
----
E
G
E
Y
I
T
Y
A
T
D
D
N
I
Y
-
M
P
D
R
L
L
----
K
M
V
-
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
44.52
25%
-105
- C2 -
1QGQ
2
SPSA_BACSU
A:
[2-128]
-----------------------------------------------------------------------------------
K
V
S
V
I
M
T
S
Y
N
-
K
S
---
D
-
Y
V
A
K
S
I
S
S
I
L
S
Q
T
F
S
---
D
--
F
E
L
F
I
M
D
D
N
S
N
E
--
E
------
T
-----
L
--
N
V
I
R
P
F
LNDNR
V
R
F
Y
-
Q
S
--
D
--
I
S
---
G
V
K
E
R
--------
T
----------------------
E
-------
K
-
T
R
-
Y
A
A
L
I
-
N
Q
A
I
E
M
A
----
E
G
E
Y
I
T
Y
A
T
D
D
N
I
Y
-
M
P
D
R
L
L
----
K
M
V
-
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
43.98
25%
-101
- C2 -
1H7Q
2
SPSA_BACSU
A:
[2-126]
-----------------------------------------------------------------------------------
K
V
S
V
I
M
T
S
Y
N
-
K
S
---
D
-
Y
V
A
K
S
I
S
S
I
L
S
Q
T
F
S
---
D
--
F
E
L
F
I
M
D
D
N
S
N
E
--
E
------
T
-----
L
--
N
V
I
R
P
F
LNDNR
V
R
F
Y
-
Q
S
--
D
--
I
S
---
G
V
K
E
R
--------
T
----------------------
E
-------
K
-
T
R
-
Y
A
A
L
I
-
N
Q
A
I
E
M
A
----
E
G
E
Y
I
T
Y
A
T
D
D
N
I
Y
-
M
P
D
R
L
L
----
K
M
V
-
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
43.87
24%
-132
- C2 -
5EKP
2
Y501_SYNY3
C:
[26-138]
----------------------------------------------------------------------------------
I
E
L
S
I
V
I
P
M
Y
N
-
E
E
DN
L
E
-
H
L
F
A
R
L
L
E
V
-
L
T
P
L
K
I
--
T
--
Y
E
I
I
C
V
N
D
G
S
K
D
--
K
------
T
-----
L
K
-
Q
L
I
D
C
Y
----------
Q
S
--
N
--
R
Q
---
I
K
I
V
N
--------
L
----------------------
S
-------
R
-
N
F
-
G
K
E
I
A
L
S
A
G
I
D
Y
A
----
Q
G
N
A
V
I
P
I
D
A
D
L
Q
D
-
P
P
E
L
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
HHSearch
43.84
19%
-134
- C2 -
2ZU9
2
MPGS_PYRHO
A:
[51-220]
----------------------------------------------------------------------------------
G
K
M
A
V
I
V
P
M
K
N
-
E
K
---
L
----
H
L
V
D
G
V
L
K
A
I
P
H
---
K
--
C
P
I
I
I
V
S
N
S
K
R
E
--
G
PN
R
Y
K
L
E
-----
V
--
D
L
I
R
H
F
----------
Y
N
L
T
H
--
S
K
---
I
I
M
I
H
--------
Q
KD
P
G
L
A
K
A
F
K
E
V
GYTDILDENG
M
-------
I
-
R
S
-
G
K
G
E
G
M
L
V
G
L
L
L
A
K
A
I
-
G
A
E
Y
V
G
F
V
D
A
D
-
N
Y
-
I
P
G
A
V
N
E
Y
V
K
D
Y
A
A
G
F
L
M
S
E
S
E
Y
T
-
M
V
R
L
H
W
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
43.79
25%
-109
- C2 -
1QG8
-
SPSA_BACSU
A:
[2-128]
-----------------------------------------------------------------------------------
K
V
S
V
I
M
T
S
Y
N
-
K
S
---
D
-
Y
V
A
K
S
I
S
S
I
L
S
Q
T
F
S
---
D
--
F
E
L
F
I
M
D
D
N
S
N
E
--
E
------
T
-----
L
--
N
V
I
R
P
F
LNDNR
V
R
F
Y
-
Q
S
--
D
--
I
S
---
G
V
K
E
R
--------
T
----------------------
E
-------
K
-
T
R
-
Y
A
A
L
I
-
N
Q
A
I
E
M
A
----
E
G
E
Y
I
T
Y
A
T
D
D
N
I
Y
-
M
P
D
R
L
L
----
K
M
V
-
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------