@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu08030: (2016-06-12 )
MTENFWRELPRPFFVLAPMEDVTDVVFRHVVSEAGRPDVFFTEFTNSESYCHPDGKDSVRGRLTFTEDEQPIVAHIWGDKPENFRKMSIGMAELGFKGLDINMGCPVPNVAGNGKGSGLICRPAVAAELIQAAKAGGLPVSVKTRLGYTDVDEWREWLTHILKQDIANLSIHLRTRAEMSKVDAHWELIPEIKKLRDEVAPDTLLTINGDIPDRQTGLKLAEQYGVDGIMIGRGIFTNPFAFEKEPKEHSSKELLDLLRLHLDLHDEYSKEEARPYKPLPRFFKIYLRGFRGASELRNQCMNTKSTDEVRALLDDFERKYLDGIE
Atome Classification :
(20 SA)
---------------------------------.........10.......-.20.--------.......30...-.....40--------------...-...------.----------..50.--.---..-----.--------..----.60---..--..-..-...70........----------------------------80-----------.........90.........100..---------.....110.......120----...---....130.-...------.---.-..140.......150---.---...--------------.----.----------------------...160--........170.----......--180--.-.-.....190---........200..---.....210--.........220..-----.....230..------.....240.-------.--------.-------..--------.-------.250------.----........---260.......270.....-..280......------.290.......300..-------......310......-------..320...
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------------MT
E
N
F
W
R
ELPR
P
F
F
V
LA
P
-
M
E
D
V
--------
T
D
V
V
F
R
H
V
V
S
EA-GRP
D
V
F
---------------
F
T
E-FTN------S----------ESYCH--P---DG-----K--------DS----VR----G
R
--
L
T
-FT-EDEQ
P
I
V
A
H
IWGD----------------------------K------------PE
N
F
R
K
M
SI
G
-
M
A
E
LGFKGLDINMG---------CPVPNVAGNGKGS
G
L
I
C
R
----
P
A
V
---
A
A
E
L
I
-
Q
A
-
A
KA------G---G-
L
P
V
S
V
K
TRLGYT
D
-----
V
---
D
E
W
--------------
R
----
E
----------------------
W
L
T
H
I
---
L
K
Q
D
IAN
L
S
I
H
L
----
R
T
R
A
E
M
--
S
K
V
--
D
-
A
-
H
W
E
L
I
P
E
----
I
K
K
L
R
D
EVAPD
T
L
---
L
T
INGD----IP
D
R
Q
T
G
L
K
L
A
E
Q
Y-----GV
D
G
I
M
IGRG------IFTNPFAFE-------K--------E-------PK--------E-------H
S
--------
S
----
K
E
L
L
D
L
L
R
---
L
H
L
DLHDEY
S
K
EEARPYK-P
L
P
R
F
F
K
I
Y
L
R
------GFR
G
A
S
E
L
R
N
Q
CM-NT-------K
S
T
D
E
V
R
A
-
L
L
D
D
F
E
-------
R
K
Y
LDGIE
42
HHSearch
88.80
23%
-93
- C3 -
4BFA
6
DUSC_ECOLI
A:
[22-337]
------------------------------------------
A
S
M
R
V
L
L
A
P
-
M
E
G
V
--------
L
D
S
L
V
R
E
L
L
T
E
V
-
N
D
Y
D
L
C
---------------
I
T
E
-
F
V
R
------
V
----------
V
D
Q
L
L
--
P
---
V
---------------
K
V
----
F
H
R
I
C
P
E
L
QN
A
S
-
R
T
-
P
S
G
T
L
V
R
V
Q
L
L
G
Q
----------------------------
F
------------
P
Q
W
L
A
E
N
A
A
R
-
A
V
E
L
G
S
W
G
V
D
L
N
C
G
---------
C
P
S
K
T
V
N
G
S
G
G
G
A
T
L
L
K
D
----
P
E
L
---
I
Y
Q
G
A
-
K
A
-
M
R
E
------
A
VPA
H
-
L
P
V
S
V
K
V
R
L
G
W
D
S
-----
G
---
E
K
K
--------------
F
----
E
----------------------
I
A
D
A
V
---
Q
Q
A
G
A
T
E
L
V
V
H
G
----
R
T
K
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Q
G
--
Y
R
A
E-
H
-
I
-
D
W
Q
A
I
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D
----
I
R
Q
R
L
-----
N
I
P
---
V
I
A
N
G
E
----
I
W
D
W
Q
S
A
Q
Q
C
M
A
I
S
-----
G
C
D
A
V
M
I
G
R
G
------
A
L
N
I
P
N
L
S
R
-------
V
--------
V
-------
K
Y
NEP-----
R
-------
M
P
--------
W
----
P
E
V
V
A
L
L
Q
---
K
Y
T
R
L
E
K
Q
G
D
T
G
L
Y
-
H
V
A
-
R
I
K
Q
W
L
S
Y
L
R
K
------
E
Y
D
E
A
T
E
L
F
Q
H
V
R
-
V
L
-------
N
N
S
P
D
I
A
R
-
A
I
Q
A
I
D
-------
I
E
K
-----
41
HHSearch
88.69
24%
-100
- C3 -
1VHN
4
?
A:
[5-309]
--------------------------------------------
V
K
V
G
L
A
P
-
M
A
G
Y
--------
T
D
S
A
F
R
T
L
A
F
E
W
--
G
A
D
F
A
---------------
F
S
E
-
M
V
S
------
A
----------
K
G
F
L
M
--
N
---
S
---------------
Q
K
----
T
E
----
E
L
--
L
--
P
Q
-
P
H
E
R
N
V
A
V
Q
I
F
G
S
----------------------------
E
------------
P
N
E
L
S
E
A
A
R
I
-
L
S
E
-
K
Y
K
W
I
D
L
N
A
G
---------
C
P
V
R
K
V
V
K
E
G
A
G
G
A
L
L
K
D
----
L
R
H
---
F
R
Y
I
V
-
R
E
-
L
R
K
S
-----
V
---
S
-
G
K
F
S
V
K
T
R
L
G
W
E
K
---------
N
E
V
--------------
E
----
E
----------------------
I
Y
R
I
L
---
V
E
E
G
V
D
E
V
F
I
H
T
----
R
T
V
V
Q
S
--
F
T
G
--
R
-
A
-
E
W
K
A
L
S
V
----
L
E
K
-------
R
I
P
---
T
F
V
S
G
D
----
I
F
T
P
E
D
A
K
R
A
L
E
E
S
-----
G
C
D
G
L
L
V
A
R
G
------
A
I
G
R
P
W
I
F
K
-------
Q
--------
I
-------
K
D
F
L
R
SG
K
Y
S
E
-------
P
S
--------
R
----
E
E
I
L
R
T
F
E
---
R
H
L
E
L
L
I
K
T
K
G
E
R
K
-
A
V
V
-
E
M
R
K
F
L
A
G
Y
T
K
------
D
L
K
G
A
R
R
F
R
E
K
V
M
-
K
I
-------
E
E
V
Q
I
L
K
E
-
M
F
Y
N
F
I
-------
K
E
V
E
----
34
Fugue
85.70
23%
-87
- C3 -
4BFA
6
DUSC_ECOLI
A:
[22-338]
------------------------------------------
A
S
M
R
V
L
L
A
P
-
M
E
G
V
--------
L
D
S
L
V
R
E
L
L
T
E
V
-
N
D
Y
D
L
C
---------------
I
T
E
-
F
V
R
------
V
----------
V
D
Q
L
L
--
P
---
V
K
-----
V
--------
F
H
----
R
I
C
PEL
Q
N
--
A
S
-
R
T
-
P
S
G
T
L
V
R
V
Q
L
L
G
Q
----------------------------
F
------------
P
Q
W
L
A
E
N
A
A
R
-
A
V
E
L
G
S
W
G
V
D
L
N
C
G
---------
C
P
S
K
T
V
N
G
S
G
G
G
A
T
L
L
K
D
----
P
E
L
---
I
Y
Q
G
A
-
K
A
-
M
R
E
A
VP---
A
---
H
-
L
P
V
S
V
K
V
R
L
G
W
D
S
-----
G
---
E
K
K
--------------
F
----
E
----------------------
I
A
D
A
V
---
Q
Q
A
G
A
T
E
L
V
V
H
G
----
R
T
K
E
Q
G
--
Y
R
A
--
E
-
H
I
D
W
Q
A
I
G
D
----
I
R
Q
R
-----
L
N
I
P
---
V
I
A
N
G
E
----
I
W
D
W
Q
S
A
Q
Q
C
M
A
I
S
-----
G
C
D
A
V
M
I
G
R
G
------
A
L
N
I
P
-
N
L
S
-------
R
--------
V
-------
V
K
--------
Y
-------
N
E
--------
P
RMP
W
P
E
V
V
A
L
L
Q
---
K
Y
T
R
L
E
K
Q
-
G
D
T
G
L
Y
H
V
A
-
R
I
K
Q
W
L
S
Y
L
R
K
------
E
Y
D
E
A
T
E
L
F
Q
H
V
R
-
V
L
-------
N
N
S
P
D
I
A
R
-
A
I
Q
A
I
D
-------
I
E
K
L
----
7
PsiBlast_PDB
82.71
24%
-95
- C3 -
1VHN
4
?
A:
[9-301]
------------------------------------------------
L
A
P
-
M
A
G
Y
--------
T
D
S
A
F
R
T
L
A
F
E
W
-
G
-
A
D
F
A
---------------
F
S
E
-
M
V
S
------
A
----------
K
G
F
L
M
--
N
---
S
Q
-----
K
--------
T
E
-----------
E
--
L
L
-
P
Q
-
P
H
E
R
N
V
A
V
Q
I
F
G
S
----------------------------
E
------------
P
N
E
L
S
E
A
A
R
I
-
L
S
E
-
K
Y
K
W
I
D
L
N
A
G
---------
C
P
V
R
K
V
V
K
E
G
A
G
G
A
L
L
K
D
L
R
H
F
R
Y
I
---
V
R
E
L
R
-
K
S
-
V
S
G
-------------
K
F
S
V
K
T
R
L
G
W
-
E
-----
K
---
N
E
V
--------------
E
----
E
----------------------
I
Y
R
I
L
---
V
E
E
G
V
D
E
V
F
I
H
T
----
R
T
V
V
Q
S
--
F
T
G
--
R
-
A
-
E
W
K
A
L
S
V
----
L
E
K
-------
R
I
P
---
T
F
V
S
G
D
----
I
F
T
P
E
D
A
K
R
A
L
E
E
S
-----
G
C
D
G
L
L
V
A
R
G
------
A
I
G
R
P
W
I
F
K
-------
Q
I
K
D
F
L
R
SG
K
-------
Y
S
--------
E
-------
P
S
--------
R
----
E
E
I
L
R
T
F
E
---
R
H
L
E
L
L
I
K
-
T
K
G
E
R
K
A
V
V
-
E
M
R
K
F
L
A
G
Y
T
K
------
D
L
K
G
A
R
R
F
R
E
K
V
M
-
K
----------
I
E
E
V
Q
I
-
L
K
E
M
F
----------------
43
HHSearch
81.82
22%
-107
- C3 -
3B0P
1
DUSAL_THET8
A:
[2-317]
------------------------------------------
L
D
P
R
L
S
V
A
P
-
M
V
D
R
--------
T
D
R
H
F
R
F
L
V
R
Q
V
-
S
L
G
V
R
L
---------------
Y
T
E
-
M
T
V
------
D
----------
Q
A
V
L
R
--
G
---
N
---------------
R
E
----------
R
L
--
L
A
-
F
R
-
P
E
E
H
P
I
A
L
Q
L
A
G
S
----------------------------
D
------------
P
K
S
L
A
E
A
A
R
I
-
G
E
A
F
G
Y
D
E
I
N
L
N
L
G
---------
C
P
S
E
K
A
Q
E
G
G
Y
G
A
C
L
L
L
D
----
L
A
R
---
V
R
E
I
L
-
K
A
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M
G
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A
-----
V
---
R
-
V
P
V
T
V
K
M
R
L
G
L
E
G
-----
K
ET
Y
R
G
L
--------------
A
----
Q
----------------------
S
V
E
A
M
---
A
E
A
G
V
K
V
F
V
V
H
A
----
R
S
A
L
-------IP
P
-
L
-
R
H
D
W
V
H
R
----
L
K
G
D
F
----
P
Q
L
T
---
F
V
T
N
G
G
----
I
R
S
L
E
E
A
L
F
H
L
K
-------
R
V
D
G
V
M
L
G
R
A
------
V
Y
E
D
P
F
V
L
E
-------
E
--------
A
-------
D
R
--------
R
VFGLP
R
R
P
S
--------
R
----
L
E
V
A
R
R
M
R
---
A
Y
L
E
E
E
V
L
K
G
T
----
P
P
W
-
A
V
L
R
H
M
L
N
L
F
R
------
G
R
P
K
G
R
L
W
R
R
L
L
S
-
E
G
-------
R
S
L
Q
A
L
D
R
-
A
L
R
L
M
E
-------
E
E
V
G
----
32
Fugue
80.74
23%
-92
- C3 -
1VHN
4
?
A:
[5-309]
--------------------------------------------
V
K
V
G
L
A
P
M
A
-
G
Y
--------
T
D
S
A
F
R
T
L
A
F
E
W
-
G
-
A
D
F
A
---------------
F
S
E
M
V
S
A
------
K
----------
G
F
L
----------
M
----
N
--------
S
Q
----
K
T
----
E
E
--
L
L
-
P
Q
-
P
H
E
R
N
V
A
V
Q
I
F
G
S
----------------------------
E
------------
P
N
E
L
S
E
A
A
R
I
-
L
S
E
-
K
Y
K
W
I
D
L
N
A
G
---------
C
P
V
R
K
V
V
K
E
G
A
G
G
A
L
L
K
D
----
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R
H
---
F
R
Y
I
V
-
R
E
-
L
R
K
------
S
V--
S
-
G
K
F
S
V
K
T
R
L
G
W
E
K
---------
N
E
V
--------------
E
----
E
----------------------
I
Y
R
I
L
---
V
E
E
G
V
D
E
V
F
I
H
T
----
R
T
V
V
Q
S
--
F
T
G
--
R
-
A
-
E
W
K
A
L
S
V
----
L
E
K
-------
R
I
P
---
T
F
V
S
G
D
----
I
F
T
P
E
D
A
K
R
A
L
E
E
S
-----
G
C
D
G
L
L
V
A
R
G
------
A
I
G
R
P
W
I
F
K
-------
Q
--------
I
-------
K
D
--------
F
-------
L
R
SG
K
Y
S
E
P
S
R
----
E
E
I
L
R
T
F
E
---
R
H
L
E
L
L
I
K
T
K
G
E
R
K
A
V
V
E
M
R
--
K
F
L
A
G
Y
T
K
------
D
L
K
G
A
R
R
F
R
E
K
-
V
M
K
I
-------
E
E
V
Q
I
L
K
E
M
F
Y
N
F
I
K
-------
E
V
E
-----
33
Fugue
77.75
22%
-97
- C3 -
3B0P
1
DUSAL_THET8
A:
[2-318]
------------------------------------------
L
D
P
R
L
S
V
A
P
-
M
V
D
R
--------
T
D
R
H
F
R
F
L
V
R
Q
V
-
S
L
G
V
R
L
---------------
Y
T
E
-
M
T
V
------
D
----------
Q
A
V
L
R
--
G
---
N
---------------------
R
E
----
R
L
--
L
A
-
F
R
-
P
E
E
H
P
I
A
L
Q
L
A
G
S
----------------------------
D
------------
P
K
S
L
A
E
A
A
R
I
-
G
E
A
F
G
Y
D
E
I
N
L
N
L
G
---------
C
P
S
E
K
A
Q
E
G
G
Y
G
A
C
L
L
L
D
----
L
A
R
---
V
R
E
I
L
-
K
A
-
M
G
E
------
A
V
--
R
-
V
P
V
T
V
K
M
R
L
G
L
E
G
-----
K
---
E
T
Y
--------------
R
----
G
----------------------
L
A
Q
S
V
---
E
A
M
A
E
A
G
V
K
V
F
V
----
V
H
A
R
S
A
--
L
I
P
--
P
-
L
-
R
H
D
W
V
H
R
----
L
K
G
D
F
----
P
Q
L
T
---
F
V
T
N
G
G
----
I
R
S
L
E
E
A
L
F
H
L
K
R
-------
V
D
G
V
M
L
G
R
A
------
V
Y
E
D
P
F
V
L
E
EADRRVF
G
--------
L
-------
P
R
--------
R
-------
P
S
--------
R
----
L
E
V
A
R
R
M
R
---
A
Y
L
E
E
E
V
L
K
G
T
----
P
P
W
-
A
V
L
R
H
M
L
N
L
F
R
------
G
R
P
K
G
R
L
W
R
R
L
L
S
-
E
G
-------
R
S
L
Q
A
L
D
R
-
A
L
R
L
M
E
-------
E
E
V
G
E
---
44
HHSearch
76.80
19%
-127
- C3 -
4XP7
1
DUS2L_HUMAN
A:
[14-321]
----------------------------------------
L
C
Y
H
N
K
L
I
L
A
P
-
M
V
R
V
--------
G
T
L
P
M
R
L
L
A
L
D
Y
--
G
A
D
I
V
---------------
Y
C
E
-
E
L
I
D
L
K
M
I
Q
C
----------
K
R
V
V
N
--
E
---
V
L
ST---
V
--------
D
F
VAPD
D
R
----
V
V
--
F
R
-
T
C
E
R
E
Q
N
R
V
V
F
Q
M
G
T
S
----------------------------
D
------------
A
E
R
A
L
A
V
A
R
L
-
V
E
-
N
D
V
A
G
I
D
V
N
M
G
---------
C
P
K
Q
---------
A
L
L
S
D
----
P
D
K
---
I
E
K
I
L
-
S
T
-
L
V
K
G
-----
T
---
R
-
R
P
V
T
C
K
I
R
I
L
P
S
L
---------
E
D
T
--------------
L
----
S
----------------------
L
V
K
R
I
---
E
R
T
G
I
A
A
I
A
V
H
G
----
R
K
R
E
E
R
--
P
Q
H
--
P
-
V
-
S
C
E
V
I
K
A
----
I
A
D
T
L
-----
S
I
P
---
V
I
A
N
G
G
SHDH
I
Q
Q
Y
S
D
I
E
D
F
R
Q
A
T
-----
A
A
S
S
V
M
V
A
R
A
------
A
M
W
N
P
S
I
F
L
-------
K
--------
E
-------
G
L
-------------------------------
R
P
L
E
E
V
M
Q
---
K
Y
I
R
Y
A
V
Q
Y
D
N
----
H
Y
T
-
N
T
K
Y
C
L
C
Q
M
L
R
------
E
Q
L
E
-
S
P
Q
G
R
L
L
H
-
A
A
-------
Q
S
S
R
E
I
C
E
-
A
F
G
------------------
2
PsiBlast_PDB
75.68
27%
-92
- C3 -
4BFA
5
DUSC_ECOLI
A:
[26-254]
----------------------------------------------
V
L
L
A
P
-
M
E
G
V
--------
L
D
S
L
V
R
E
L
L
T
E
V
-
N
D
Y
D
L
C
---------------
I
T
E
-
F
V
R
------
V
VDQLLP
V
K
V
F
H
R
I
C
---
P
---
E
L
-----
Q
--------
N
A
----
S
R
------------
T
-
P
S
G
T
L
V
R
V
Q
L
L
G
Q
----------------------------
F
------------
P
Q
W
L
A
E
N
A
A
R
-
A
V
E
L
G
S
W
G
V
D
L
N
C
G
---------
C
P
S
K
T
V
N
G
S
G
G
G
A
T
L
L
K
D
----
P
E
L
I
Y
Q
G
A
K
A
M
-
R
E
-
A
V
P
------
A
---
H
-
L
P
V
S
V
K
V
R
L
G
W
D
S
-----
G
---
E
K
K
--------------
F
----
E
----------------------
I
A
D
A
V
---
Q
Q
A
G
A
T
E
L
V
V
H
G
----
R
T
K
E
Q
G
--
Y
R
A
--
E
H
I
-
D
W
Q
A
I
G
D
----
I
R
Q
-----
R
L
N
I
P
---
V
I
A
N
G
E
----
I
W
D
W
Q
S
A
Q
Q
C
M
A
I
S
-----
G
C
D
A
V
M
I
G
R
G
------
A
L
N
I
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
75.63
24%
-95
- C3 -
3B0U
3
DUSAL_THET8
X:
[4-263]
--------------------------------------------
P
R
L
S
V
A
P
-
M
V
D
R
--------
T
D
R
H
F
R
F
L
V
R
Q
V
-
S
L
G
V
R
L
---------------
Y
T
E
-
M
T
V
------
D
----------
Q
A
V
L
R
--
G
---
N
R
-----
E
--------
R
L
--------------
L
A
-
F
R
-
P
E
E
H
P
I
A
L
Q
L
A
G
S
----------------------------
D
------------
P
K
S
L
A
E
A
A
R
I
-
G
E
A
F
G
Y
D
E
I
N
L
N
L
G
---------
C
P
S
E
K
A
Q
E
G
G
Y
G
A
C
L
L
L
D
----
L
A
R
---
V
R
E
I
L
-
K
A
M
G
E
A
------
V
---
R
-
V
P
V
T
V
K
M
R
L
G
L
E
G
-----
K
---
E
T
Y
--------------
R
GLA-
Q
----------------------
S
V
E
A
M
---
A
E
A
G
V
K
V
F
V
V
H
A
----
R
S
A
L
L
A
--
L
S
T
--
K
-
A
-
N
R
E
I
P
P
L
RHDW
V
H
R
L
K
G
D
F
-
P
Q
L
T
---
F
V
T
N
G
G
----
I
R
S
L
E
E
A
L
F
H
L
K
R
-------
V
D
G
V
M
L
G
R
A
------
V
Y
E
D
P
F
V
L
E
-------
E
--------
A
DRRVFGL
P
R
--------
R
-------
P
S
--------
R
----
L
E
V
A
R
R
M
R
---
A
Y
L
E
-------------------------------------------------------------------------------------
8
PsiBlast_PDB
75.54
28%
-92
- C3 -
4BF9
1
DUSC_ECOLI
A:
[26-254]
----------------------------------------------
V
L
L
A
P
-
M
E
G
V
--------
L
D
S
L
V
R
E
L
L
T
E
V
-
N
D
Y
D
L
C
---------------
I
T
E
-
F
V
R
------
V
VDQLLP
V
K
V
F
H
R
I
C
---
P
---
E
L
-----
Q
--------
N
A
----
S
R
------------
T
-
P
S
G
T
L
V
R
V
Q
L
L
G
Q
----------------------------
F
------------
P
Q
W
L
A
E
N
A
A
R
-
A
V
E
L
G
S
W
G
V
D
L
N
C
G
---------
C
P
S
K
T
V
N
G
S
G
G
G
A
T
L
L
K
D
----
P
-------
E
L
I
Y
Q
G
-
A
K
A
M
R
E
A
VP
A
---
H
-
L
P
V
S
V
K
V
R
L
G
W
D
S
-----
G
---
E
K
K
--------------
F
----
E
----------------------
I
A
D
A
V
---
Q
Q
A
G
A
T
E
L
V
V
H
G
----
R
T
K
E
Q
G
--
Y
R
A
--
E
H
I
-
D
W
Q
A
I
G
D
----
I
R
Q
R
L
-----
N
I
P
---
V
I
A
N
G
E
----
I
W
D
W
Q
S
A
Q
Q
C
M
A
I
S
-----
G
C
D
A
V
M
I
G
R
G
------
A
L
N
I
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
75.22
27%
-89
- C3 -
4YCP
1
DUSC_ECOLI
A:
[9-237]
----------------------------------------------
V
L
L
A
P
-
M
E
G
V
--------
L
D
S
L
V
R
E
L
L
T
E
V
-
N
D
Y
D
L
C
---------------
I
T
E
-
F
V
R
------
V
VDQLLP
V
K
V
F
H
R
I
C
---
P
---
E
L
-----
Q
--------
N
A
----
S
R
------------
T
-
P
S
G
T
L
V
R
V
Q
L
L
G
Q
----------------------------
F
------------
P
Q
W
L
A
E
N
A
A
R
-
A
V
E
L
G
S
W
G
V
D
L
N
C
G
---------
A
P
-------
G
G
G
A
T
L
L
K
D
----
P
E
L
I
Y
Q
G
A
K
A
M
-
R
E
-
A
V
P
------
A
---
H
-
L
P
V
S
V
K
V
R
L
G
W
D
S
-----
G
---
E
K
K
--------------
F
----
E
----------------------
I
A
D
A
V
---
Q
Q
A
G
A
T
E
L
V
V
H
G
----
R
T
K
E
Q
G
--
Y
R
A
--
E
H
I
-
D
W
Q
A
I
G
D
----
I
R
Q
-----
R
L
N
I
P
---
V
I
A
N
G
E
----
I
W
D
W
Q
S
A
Q
Q
C
M
A
I
S
-----
G
C
D
A
V
M
I
G
R
G
------
A
L
N
I
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
75.01
27%
-94
- C3 -
4YCO
1
DUSC_ECOLI
A:
[9-237]
----------------------------------------------
V
L
L
A
P
-
M
E
G
V
--------
L
D
S
L
V
R
E
L
L
T
E
V
-
N
D
Y
D
L
C
---------------
I
T
E
-
F
V
R
------
V
VDQLLP
V
K
V
F
H
R
I
C
---
P
---
E
L
-----
Q
--------
N
A
----
S
R
------------
T
-
P
S
G
T
L
V
R
V
Q
L
L
G
Q
----------------------------
F
------------
P
Q
W
L
A
E
N
A
A
R
-
A
V
E
L
G
S
W
G
V
D
L
N
C
G
---------
A
P
S
----
G
S
G
G
G
A
T
L
L
K
D
----
P
E
L
I
Y
Q
G
A
K
A
M
-
R
E
-
A
V
P
------
A
---
H
-
L
P
V
S
V
K
V
R
L
G
W
D
S
-----
G
---
E
K
K
--------------
F
----
E
----------------------
I
A
D
A
V
---
Q
Q
A
G
A
T
E
L
V
V
H
G
----
R
T
K
E
Q
G
--
Y
R
A
--
E
H
I
-
D
W
Q
A
I
G
D
----
I
R
Q
-----
R
L
N
I
P
---
V
I
A
N
G
E
----
I
W
D
W
Q
S
A
Q
Q
C
M
A
I
S
-----
G
C
D
A
V
M
I
G
R
G
------
A
L
N
I
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
74.06
24%
-101
- C3 -
3B0P
1
DUSAL_THET8
A:
[4-263]
--------------------------------------------
P
R
L
S
V
A
P
-
M
V
D
R
--------
T
D
R
H
F
R
F
L
V
R
Q
V
-
S
L
G
V
R
L
---------------
Y
T
E
-
M
T
V
------
D
----------
Q
A
V
L
R
--
G
---
N
R
-----
E
--------
R
L
--------------
L
A
-
F
R
-
P
E
E
H
P
I
A
L
Q
L
A
G
S
----------------------------
D
------------
P
K
S
L
A
E
A
A
R
I
-
G
E
A
F
G
Y
D
E
I
N
L
N
L
G
---------
C
P
S
E
K
A
Q
E
G
G
Y
G
A
C
L
L
L
D
----
L
A
R
---
V
R
E
I
L
-
K
A
M
G
E
A
------
V
---
R
-
V
P
V
T
V
K
M
R
L
G
L
E
G
-----
K
---
E
T
Y
--------------
R
G
L
A
-
Q
----------------------
S
V
E
A
M
---
A
E
A
G
V
K
V
F
V
V
H
A
----
R
S
A
L
----------------
I
P
P
L
R
H
D
W
V
H
R
L
K
G
D
F
-
P
Q
L
T
---
F
V
T
N
G
G
----
I
R
S
L
E
E
A
L
F
H
L
K
R
-------
V
D
G
V
M
L
G
R
A
------
V
Y
E
D
P
F
V
L
E
-------
E
--------
A
DRRVFGL
P
R
--------
R
-------
P
S
--------
R
----
L
E
V
A
R
R
M
R
---
A
Y
L
E
-------------------------------------------------------------------------------------
1
PsiBlast_PDB
73.32
27%
-103
- C3 -
3W9Z
1
DUSC_ECOLI
A:
[3-242]
----------------------------------------------
V
L
L
A
P
-
M
E
G
V
--------
L
D
S
L
V
R
E
L
L
T
E
V
-
N
D
Y
D
L
C
---------------
I
T
E
-
F
V
R
------
V
VDQLLP
V
K
V
F
H
R
I
C
---
P
---
E
L
-----
Q
--------
N
A
----
S
R
------------
T
-
P
S
G
T
L
V
R
V
Q
L
L
G
Q
----------------------------
F
------------
P
Q
W
L
A
E
N
A
A
R
-
A
V
E
L
G
S
W
G
V
D
L
N
C
G
---------
C
-------------
L
L
K
D
----
P
E
L
I
Y
Q
G
A
K
A
M
-
R
E
-
A
V
P
------
A
---
H
-
L
P
V
S
V
K
V
R
L
G
W
D
S
-----
G
---
E
K
K
--------------
F
----
E
----------------------
I
A
D
A
V
---
Q
Q
A
G
A
T
E
L
V
V
H
G
----
R
T
K
E
Q
G
--
Y
R
A
--
E
H
I
-
D
W
Q
A
I
G
D
----
I
R
Q
-----
R
L
N
I
P
---
V
I
A
N
G
E
----
I
W
D
W
Q
S
A
Q
Q
C
M
A
I
S
-----
G
C
D
A
V
M
I
G
R
G
------
A
L
N
I
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
70.89
22%
-131
- C3 -
4XP7
1
DUS2L_HUMAN
A:
[20-261]
----------------------------------------------
L
I
L
A
P
-
M
V
R
V
--------
G
T
L
P
M
R
L
L
A
L
D
Y
-
G
A
D
I
V
Y
CEEL
I
D
L
K
M
I
Q
C
K
R
V
V
N
E
-
V
L
S
------
T
----------
V
D
F
V
A
--
P
---
D
D
-----
R
--------
V
V
----
F
R
---------
T
-
C
E
-
R
E
Q
N
R
V
V
F
Q
M
G
T
S
----------------------------
D
------------
A
E
--
R
A
L
A
V
A
R
L
V
E
N
D
V
A
G
I
D
V
N
M
G
---------
C
P
K
Q
---------
A
L
L
S
D
----
P
D
K
---
I
E
K
I
L
-
S
T
L
V
K
G
------
T
---
R
-
R
P
V
T
C
K
I
R
I
-
L
P
S
-----
L
---
E
D
T
--------------
L
----
S
----------------------
L
V
K
R
I
---
E
R
T
G
I
A
A
I
A
V
H
G
----
R
K
R
E
E
R
--
P
Q
H
--
P
-
V
-
S
C
E
V
I
K
A
----
I
--------
A
D
T
L
S
I
P
V
I
A
N
G
G
----
S
H
D
H
I
Q
Q
Y
S
D
I
E
D
F
R
Q
A
T-
A
A
S
S
V
M
V
A
R
A
------
A
M
W
N
P
S
I
F
L
-------
K
--------
E
--------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
70.64
24%
-95
- C3 -
3B0V
1
DUSAL_THET8
C:
[25-258]
--------------------------------------------
P
R
L
S
V
A
P
-
M
V
D
R
--------
T
D
R
H
F
R
F
L
V
R
Q
V
-
S
L
G
V
R
L
---------------
Y
T
E
-
M
T
V
------
D
----------
Q
A
V
L
R
--
G
---
N
R
-----
E
--------
R
L
--------------
L
A
-
F
R
-
P
E
E
H
P
I
A
L
Q
L
A
G
S
----------------------------
D
------------
P
K
S
L
A
E
A
A
R
I
-
G
E
A
F
G
Y
D
E
I
N
L
N
L
G
---------
C
P
S
E
K
A
Q
E
G
G
Y
G
A
C
L
L
L
D
----
L
A
R
---
V
R
E
I
L
-
K
A
M
G
E
A
------
V
---
R
-
V
P
V
T
V
K
M
R
L
G
L
E
G
-----
K
---
E
T
Y
--------------
R
----
G
----------------------
L
A
Q
S
V
EAM
A
E
A
G
V
K
V
F
V
V
H
A
----
R
S
A
L
L
A
--
L
S
T
--
K
-
A
-
N
R
E
I
P
P
L
RHDW
V
H
R
L
K
G
D
F
-
P
Q
L
T
---
F
V
T
N
G
G
----
I
R
S
L
E
E
A
L
F
H
L
K
R
-------
V
D
G
V
M
L
G
R
A
------
V
Y
E
D
P
F
V
L
E
-------
E
-----------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
68.69
22%
-129
- C3 -
4WFS
4
DUS2L_HUMAN
A:
[8-249]
----------------------------------------------
L
I
L
A
P
-
M
V
R
V
--------
G
T
L
P
M
R
L
L
A
L
D
Y
-
G
A
D
I
V
Y
C
E
ELI
D
L
K
M
I
Q
C
K
R
V
V
N
E
-
V
L
S
------
T
----------
V
D
F
V
A
--
P
---
D
D
-----
R
--------
V
V
----
F
R
---------
T
-
C
E
-
R
E
Q
N
R
V
V
F
Q
M
G
T
S
----------------------------
D
------------
A
E
--
R
A
L
A
V
A
R
L
V
E
N
D
V
A
G
I
D
V
N
M
G
----------------------
A
L
L
S
D
----
P
D
K
---
I
E
K
I
L
-
S
T
L
V
K
G
------
T
---
R
-
R
P
V
T
C
K
I
R
I
-
L
P
S
-----
L
---
E
D
T
--------------
L
----
S
----------------------
L
V
K
R
I
---
E
R
T
G
I
A
A
I
A
V
H
G
----
R
K
R
E
E
R
--
P
Q
H
--
P
-
V
-
S
C
E
V
I
K
A
----
I
--------
A
D
T
L
S
I
P
V
I
A
N
G
G
----
S
H
D
H
I
Q
Q
Y
S
D
I
E
D
F
R
Q
A
T
-
A
A
S
S
V
M
V
A
R
A
------
A
M
W
N
P
S
I
F
L
-------
K
--------
E
--------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
65.39
20%
-71
- C2 -
5DBJ
2
?
D:
[5-441]
SDHDYDVVIIGGGPAGSTMASYLAKAGVKCAVF
E
K
E
L
F
E
R
E
H
V
G
E
S
L
V
P
A
T
-
T
P
V
L
--------
L
E
I
G
V
M
E
K
I
E
K
A
-
N
F
P
K
K
F
---------------
G
A
A
-
W
T
S
------
A
----------
D
S
--
G
--
P
---
E
D
-----
K
MGFQGLDH
D
F
----
R
S
----
A
E
--
I
L
-
F
N
-
E
R
K
Q
E
G
V
D
R
D
F
T
F
----------------------------
H
------------
V
D
R
G
K
F
D
R
I
L
-
L
E
H
A
G
S
L
G
A
K
V
F
Q
G
---------
V
E
I
A
D
V
E
F
L
S
P
G
N
V
I
V
N
A
KLGK
R
S
V
---
E
I
K
A
K
-
M
V
-
V
D
A
------
S
---
G
-
R
N
V
L
L
G
R
R
L
G
L
R
E
-----
K
---
D
P
V
FNQFAIHSWFDNFD
R
----
K
SATQSPDKVDYIFIHFLPMTNT
W
V
W
Q
I
P--
I
T
E
T
I
T
S
V
G
V
V
T
QKQN
Y
T
N
S
D
L
--
T
Y
E
--
E
-
F
-
F
W
E
A
V
K
T
----
R
E
N
L
H
D
A
L
K
A
S
E
Q
---
V
R
P
F
K
K
----
E
A
D
Y
S
Y
G
M
K
--
E
V
C
-----
G
D
S
F
V
L
I
G
D
A
ARFVDP
I
F
S
S
G
V
S
V
A
-------
L
--------
N
-------
S
A
--------
R
-------
I
A
--------
S
----
G
D
I
I
E
A
V
K
NND
F
S
K
S
S
F
T
H
Y
E
G
M
I
R
N
G
I
K
-
N
W
Y
E
F
I
T
L
Y
Y
R
LNILFT
A
F
V
Q
D
P
R
Y
R
L
D
I
L
-
Q
L
LQGDVYL
E
V
L
D
K
M
R
E
-
I
I
A
A
V
E
SDPEHLW
H
K
Y
L
G
---
59
HHSearch
63.95
18%
-113
- C3 -
4QNW
6
OYE3_ASPFU
A:
[19-338]
----------------------------------------
C
H
L
Q
H
R
M
I
M
A
P
-
T
T
R
F
RADGQGVP
L
P
F
V
Q
E
Y
Y
G
Q
R
A
S
V
P
G
T
L
L
---------------
I
T
E
-
A
T
D
------
I
----------
T
P
K
A
M
GY
K
HVP
G
I
WS
E
P
Q
R
--------
E
A
----
W
R
----
E
I
--
V
S
R
V
H
-
S
K
K
C
F
I
F
C
Q
L
W
A
T
GRAADPDVLADMKDLISSSAVPVEEKGP
L
P
R
A
L
T
E
D
E
I
Q
Q
C
I
A
D
F
A
Q
A
A
R
N
-
A
I
N
A
G
F
D
G
V
E
I
H
G
A
NGY
L
I
D
Q
F
T
Q
K
S
C
N
H
R
Q
D
R
W
G
G
S
I
E
N
R
----
A
R
F
---
A
V
E
V
T
-
R
A
-
V
I
E
A
-----
V
---
G
A
D
R
V
G
V
K
L
S
P
Y
S
Q
Y
LGMGT
M
---
D
E
L
--------------
V
P
Q
F
E
Y
----------------------
L
I
A
Q
M
---
R
R
L
D
V
A
Y
L
H
L
A
N
----
S
R
W
L
D
E
EK
P
H
P
--
D
-
P
-
N
H
E
V
F
V
R
----
V
W
G
-
Q
-----
S
S
P
---
I
L
L
A
G
G
----
Y
-
D
A
A
S
A
E
K
V
T
E
Q
M
A
A
A
TY
T
N
V
A
I
A
F
G
R
Y
------
F
I
S
T
P
D
L
P
F
-------
R
--------
V
-------
M
A
-----------------------------------------------------------------------------------------------------------------------------------