@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu10560: (2016-06-16 )
MPTIDEIAKLCNVSKTTVSRVLNNHPYVSKEKRDMILKAINELDYTPNYLARNFRRNKTQTIALSVPSIDHPFFAQLIKGVSHEVLFKNYKVIVFQTFYDKQTELELLELLKHKEVDGIILGTLENEWDQISPFLKYGPILLCNEYHHSADITIIGYDEFEAAYMGVVHLIERGHKKIGFCFDTPYSEAQCQRKEGYLKALQDYNLHHRSEWIFGEMFNIEDGFRVFHKIKDLKDRPSAIFTGNDQVAAGIIKQAMKNGFKVPEDLAVIGFDNQLICQVVTPTITTIDIPVIELGQQAVLKIIESISGNASLNRRIIKLPTKLIIREST
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120-........130.--.....--.140.......-150.......-160.......170.......180.......--190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MP
T
I
D
E
I
A
K
L
CNV
S
K
T
T
V
S
R
V
L
NNHPYV
S
K
E
K
R
D
M
I
L
K
A
I
N
ELDYT
P
N
Y
L
A
R
N
FRRNK
T
Q
T
I
A
L
SVPSID
H
P
F
F
A
Q
L
I
K
G
V
S
H
E
V
L
FKN
Y
K
V
I
V
F
Q
TFYDKQ
T
E
L
E
L
L
E
L
L
K
HKEVD
G
I
I
L
--GTLEN
E
W
D
QI
S
P
--
F
L
KYG--
P
I
L
L
CNEYHHS-A
D
I
T
I
I
G
Y
D
E
-
F
E
A
A
Y
M
G
V
V
H
L
I
ERGH
K
K
I
G
F
C
FDTPY
S
E
A
--
Q
C
Q
R
K
E
G
Y
L
K
A
L
Q
DYN
L
H
H
R
SEWIF
G
E
MFNI
E
D
G
F
R
V
F
H
K
I
K
D
LKDRP
S
A
I
FTGN
D
Q
V
A
A
G
I
I
K
Q
A
M
KNGFKVPE
D
L
A
V
I
GFDN
Q
L
I
C
Q
VVTP
T
I
T
T
I
D
I
P
V
I
EL
G
Q
Q
A
V
L
K
I
I
E
S
ISGNASLN
R
R
I
IKLP
T
K
L
I
I
REST
26
PsiBlast_CBE
74.56
31%
-115
- C3 -
1BDH
2
PURR_ECOLI
A:
[2-329]
--
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
A
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
--
M
C
S
E
Y
P
E
P
L
L
A
M
--
L
E
E
Y
R
HI
P
M
V
V
M
D
W
G
E
A
K
-
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
R
N
T
--
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
V
-
N
K
R
E
E
P
Q
S
I
E
V
H
P
R
L
I
E
R
R
S
-
18
PsiBlast_PDB
73.72
31%
-115
- C3 -
2PUE
2
PURR_ECOLI
A:
[2-329]
--
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
--
M
C
S
E
Y
P
E
P
L
L
A
M
--
L
E
E
Y
R
HI
P
M
V
V
M
D
W
G
E
A
K
-
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
Q
N
T
--
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
V
-
N
K
R
E
E
P
Q
S
I
E
V
H
P
R
L
I
E
R
R
S
-
16
PsiBlast_PDB
73.69
31%
-114
- C3 -
1QPZ
2
PURR_ECOLI
A:
[2-329]
--
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
--
M
C
S
E
Y
P
E
P
L
L
A
M
--
L
E
E
Y
R
HI
P
M
V
V
M
D
W
G
E
A
K
-
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
R
N
T
--
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
V
-
N
K
R
E
E
P
Q
S
I
E
V
H
P
R
L
I
E
R
R
S
-
4
PsiBlast_PDB
73.58
29%
-116
- C3 -
3OQO
4
CCPA_BACSU
A:
[4-331]
--
T
I
Y
D
V
A
R
E
A
N
V
S
M
A
T
V
S
R
V
V
N
G
N
P
N
V
K
P
T
T
R
K
K
V
L
E
A
I
E
R
L
G
Y
R
P
N
A
V
A
R
G
L
A
S
K
K
T
T
T
V
G
V
I
I
P
D
I
S
S
I
F
Y
S
E
L
A
R
G
I
E
D
I
A
T
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
M
E
K
E
L
H
L
L
N
T
M
L
G
K
Q
V
D
G
I
V
F
M
G
G
N
I
T
D
E
--
H
V
A
E
--
F
K
R
S
P
V
-
P
I
V
L
A
A
S
V
E
E
Q
-
E
E
T
P
S
V
A
I
D
Y
-
E
Q
A
I
Y
D
A
V
K
L
L
V
D
K
G
H
T
D
I
A
F
V
-
S
G
P
M
A
E
P
IN
R
S
K
K
L
Q
G
Y
K
R
A
L
E
E
A
N
L
P
F
N
E
Q
F
V
A
E
G
D
Y
T
Y
D
S
G
L
E
A
L
Q
H
L
M
S
L
D
K
K
P
T
A
I
L
S
A
T
D
E
M
A
L
G
I
I
H
A
A
Q
D
Q
G
L
S
I
P
E
D
L
D
I
I
G
F
D
N
T
R
L
S
L
M
V
R
P
Q
L
S
T
V
V
Q
P
T
Y
D
I
G
A
V
A
-
M
R
L
L
T
K
L
M
N
K
E
P
V
E
E
H
I
V
E
L
P
H
R
I
E
L
R
K
S
T
21
PsiBlast_CBE
73.48
31%
-116
- C3 -
1VPW
2
PURR_ECOLI
A:
[2-329]
--
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
M
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
--
M
C
S
E
Y
P
E
P
L
L
A
M
--
L
E
E
Y
R
HI
P
M
V
V
M
D
W
G
E
A
K
-
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
R
N
T
--
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
V
-
N
K
R
E
E
P
Q
S
I
E
V
H
P
R
L
I
E
R
R
S
-
6
PsiBlast_PDB
73.18
31%
-116
- C3 -
2PUB
2
PURR_ECOLI
A:
[2-329]
--
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
--
M
C
S
E
Y
P
E
P
L
L
A
M
--
L
E
E
Y
R
HI
P
M
V
V
M
D
W
G
E
A
K
-
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
A
N
T
--
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
V
-
N
K
R
E
E
P
Q
S
I
E
V
H
P
R
L
I
E
R
R
S
-
7
PsiBlast_PDB
72.99
31%
-115
- C3 -
2PUC
2
PURR_ECOLI
A:
[2-329]
--
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
--
M
C
S
E
Y
P
E
P
L
L
A
M
--
L
E
E
Y
R
HI
P
M
V
V
M
D
W
G
E
A
K
-
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
A
N
T
--
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
V
-
N
K
R
E
E
P
Q
S
I
E
V
H
P
R
L
I
E
R
R
S
-
13
PsiBlast_PDB
72.88
31%
-115
- C3 -
1WET
2
PURR_ECOLI
A:
[2-329]
--
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
--
M
C
S
E
Y
P
E
P
L
L
A
M
--
L
E
E
Y
R
HI
P
M
V
V
M
D
W
G
E
A
K
-
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
R
N
T
--
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
V
-
N
K
R
E
E
P
Q
S
I
E
V
H
P
R
L
I
E
R
R
S
-
24
PsiBlast_CBE
72.86
31%
-113
- C3 -
1QQA
2
PURR_ECOLI
A:
[2-329]
--
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
A
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
--
M
C
S
E
Y
P
E
P
L
L
A
M
--
L
E
E
Y
R
HI
P
M
V
V
M
D
W
G
E
A
K
-
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
R
N
T
--
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
V
-
N
K
R
E
E
P
Q
S
I
E
V
H
P
R
L
I
E
R
R
S
-
48
HHSearch
72.85
30%
-113
- C3 -
1QPZ
2
PURR_ECOLI
A:
[1-330]
-
A
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
-
C
S
E
Y
P
-
E
P
L
L
A
M
L
E
E
Y
R
H
I
--
P
M
V
V
M
D
W
G
E
A
K
A
D
F
T
D
A
V
I
D
N
A
-
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
R
N
T
--
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
V
N
K
R
E
-
E
P
Q
S
I
E
V
H
P
R
L
I
E
R
R
S
V
20
PsiBlast_PDB
72.74
31%
-114
- C3 -
2PUG
2
PURR_ECOLI
A:
[2-329]
--
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
--
M
C
S
E
Y
P
E
P
L
L
A
M
--
L
E
E
Y
R
HI
P
M
V
V
M
D
W
G
E
A
K
-
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
Q
N
T
--
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
V
-
N
K
R
E
E
P
Q
S
I
E
V
H
P
R
L
I
E
R
R
S
-
23
PsiBlast_CBE
72.69
31%
-112
- C3 -
1QQB
2
PURR_ECOLI
A:
[2-329]
--
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
A
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
--
M
C
S
E
Y
P
E
P
L
L
A
M
--
L
E
E
Y
R
HI
P
M
V
V
M
D
W
G
E
A
K
-
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
R
N
T
--
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
V
-
N
K
R
E
E
P
Q
S
I
E
V
H
P
R
L
I
E
R
R
S
-
17
PsiBlast_PDB
72.60
31%
-113
- C3 -
1ZAY
2
PURR_ECOLI
A:
[2-329]
--
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
--
M
C
S
E
Y
P
E
P
L
L
A
M
--
L
E
E
Y
R
HI
P
M
V
V
M
D
W
G
E
A
K
-
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
R
N
T
--
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
V
-
N
K
R
E
E
P
Q
S
I
E
V
H
P
R
L
I
E
R
R
S
-
2
PsiBlast_PDB
72.58
29%
-112
- C3 -
3OQM
4
CCPA_BACSU
A:
[4-331]
--
T
I
Y
D
V
A
R
E
A
N
V
S
M
A
T
V
S
R
V
V
N
G
N
P
N
V
K
P
T
T
R
K
K
V
L
E
A
I
E
R
L
G
Y
R
P
N
A
V
A
R
G
L
A
S
K
K
T
T
T
V
G
V
I
I
P
D
I
S
S
I
F
Y
S
E
L
A
R
G
I
E
D
I
A
T
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
M
E
K
E
L
H
L
L
N
T
M
L
G
K
Q
V
D
G
I
V
F
M
G
G
N
I
T
D
E
--
H
V
A
E
--
F
K
R
S
P
V
-
P
I
V
L
A
A
S
V
E
E
Q
-
E
E
T
P
S
V
A
I
D
Y
-
E
Q
A
I
Y
D
A
V
K
L
L
V
D
K
G
H
T
D
I
A
F
V
-
S
G
P
M
A
E
P
IN
R
S
K
K
L
Q
G
Y
K
R
A
L
E
E
A
N
L
P
F
N
E
Q
F
V
A
E
G
D
Y
T
Y
D
S
G
L
E
A
L
Q
H
L
M
S
L
D
K
K
P
T
A
I
L
S
A
T
D
E
M
A
L
G
I
I
H
A
A
Q
D
Q
G
L
S
I
P
E
D
L
D
I
I
G
F
D
N
T
R
L
S
L
M
V
R
P
Q
L
S
T
V
V
Q
P
T
Y
D
I
G
A
V
A
-
M
R
L
L
T
K
L
M
N
K
E
P
V
E
E
H
I
V
E
L
P
H
R
I
E
L
R
K
S
T
15
PsiBlast_PDB
72.57
31%
-114
- C3 -
1QP4
2
PURR_ECOLI
A:
[2-329]
--
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
--
M
C
S
E
Y
P
E
P
L
L
A
M
--
L
E
E
Y
R
HI
P
M
V
V
M
D
W
G
E
A
K
-
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
R
N
T
--
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
V
-
N
K
R
E
E
P
Q
S
I
E
V
H
P
R
L
I
E
R
R
S
-
11
PsiBlast_PDB
72.54
31%
-117
- C3 -
1PNR
2
PURR_ECOLI
A:
[2-329]
--
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
--
M
C
S
E
Y
P
E
P
L
L
A
M
--
L
E
E
Y
R
HI
P
M
V
V
M
D
W
G
E
A
K
-
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
R
N
T
--
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
V
-
N
K
R
E
E
P
Q
S
I
E
V
H
P
R
L
I
E
R
R
S
-
3
PsiBlast_PDB
72.54
29%
-118
- C3 -
3OQN
2
CCPA_BACSU
A:
[4-331]
--
T
I
Y
D
V
A
R
E
A
N
V
S
M
A
T
V
S
R
V
V
N
G
N
P
N
V
K
P
T
T
R
K
K
V
L
E
A
I
E
R
L
G
Y
R
P
N
A
V
A
R
G
L
A
S
K
K
T
T
T
V
G
V
I
I
P
D
I
S
S
I
F
Y
S
E
L
A
R
G
I
E
D
I
A
T
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
M
E
K
E
L
H
L
L
N
T
M
L
G
K
Q
V
D
G
I
V
F
M
G
G
N
I
T
D
E
--
H
V
A
E
--
F
K
R
S
P
V
-
P
I
V
L
A
A
S
V
E
E
Q
-
E
E
T
P
S
V
A
I
D
Y
-
E
Q
A
I
Y
D
A
V
K
L
L
V
D
K
G
H
T
D
I
A
F
V
-
S
G
P
M
A
E
P
IN
R
S
K
K
L
Q
G
Y
K
R
A
L
E
E
A
N
L
P
F
N
E
Q
F
V
A
E
G
D
Y
T
Y
D
S
G
L
E
A
L
Q
H
L
M
S
L
D
K
K
P
T
A
I
L
S
A
T
D
E
M
A
L
G
I
I
H
A
A
Q
D
Q
G
L
S
I
P
E
D
L
D
I
I
G
F
D
N
T
R
L
S
L
M
V
R
P
Q
L
S
T
V
V
Q
P
T
Y
D
I
G
A
V
A
-
M
R
L
L
T
K
L
M
N
K
E
P
V
E
E
H
I
V
E
L
P
H
R
I
E
L
R
K
S
T
8
PsiBlast_PDB
72.38
31%
-114
- C3 -
2PUD
2
PURR_ECOLI
A:
[2-329]
--
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
--
M
C
S
E
Y
P
E
P
L
L
A
M
--
L
E
E
Y
R
HI
P
M
V
V
M
D
W
G
E
A
K
-
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
A
N
T
--
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
V
-
N
K
R
E
E
P
Q
S
I
E
V
H
P
R
L
I
E
R
R
S
-
10
PsiBlast_PDB
72.37
31%
-112
- C3 -
1JFT
3
PURR_ECOLI
A:
[2-329]
--
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
--
M
C
S
E
Y
P
E
P
L
L
A
M
--
L
E
E
Y
R
HI
P
M
V
V
M
D
A
G
E
A
K
-
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
R
N
T
--
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
V
-
N
K
R
E
E
P
Q
S
I
E
V
H
P
R
L
I
E
R
R
S
-
25
PsiBlast_CBE
72.21
31%
-115
- C3 -
1QP7
2
PURR_ECOLI
A:
[2-329]
--
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
A
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
--
M
C
S
E
Y
P
E
P
L
L
A
M
--
L
E
E
Y
R
HI
P
M
V
V
M
D
W
G
E
A
K
-
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
R
N
T
--
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
V
-
N
K
R
E
E
P
Q
S
I
E
V
H
P
R
L
I
E
R
R
S
-