@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu10790: (2016-06-16 )
MCGITGWVDFKKQLVQEKQTMDRMTDTLSKRGPDDSNVWGEHHVLFGHKRLAVVDIEGGRQPMACTYKGDTYTIIYNGELYNTEDLRKELRARGHQFERTSDTEVLLHSYIEWQEDCVDHLNGIFAFAVWDEKRNLLFAARDRLGVKPFFYTKEGSSFLFGSEIKAILAHPDIKARVDRTGLSEIFGLGPSRTPGTGIFKGIKEIRPAHALTFSKDGLNIWRYWNVESEKHTDSFDDTVANVRSLFQDAVTRQLVSDVPVCTFLSGGLDSSAITAIAAGHFEKEGKAPLHTYSIDYEENDKYFQASAFQPNDDGPWIEKMTEAFGTTHHKCVISQKDLVDHLEEAVLVKDLPGMADVDSSLLWFCREIKKDFVVSLSGECADEIFGGYPWFHTADVESGFPWMRSTEERIKLLSDSWQKKLNLKEYVNAKYEETLAETPLLDGETGVDKARRQLFYLNMLWFMTNLLDRKDRMSMGASLEVRVPFADHRLVEYVWNIPWEMKMHDNREKGILRKALEGILPDDILYRKKSPYPKTHHPEYTKGVSEWLKTIRSQKDSVLHTLLDRKQLDQLLETEGSSFKVPWFGQLMKGPQLIAHLAQIHTWFEAYRIDIDER
Atome Classification :
(20 SA)
-----.........10........20........30........--40----------------------------........50.....--.--..60........70........80........90..-......100.......110---.---.-.------.-----------------.-----------...120.......130..-.....140.......150...-..-----.-...160.......170.......180.......190.......200.......210---....--.--..220.......230...------...-----...240--........250...-....260.......270....----...280.......290.......300.......310.......320.......330.......340.......350-.--..--.....360.--........370-..-......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500....-...510.....--..520.......530.......540...-....550......--------------.560.......570.......580.......590.......600.......610..
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----MCGI
T
G
W
V
D
F
K
K
Q
L
V
Q
E
K
Q
T
M
D
R
M
T
D
T
L
SKRGPDDSNVW--GE----------------------------H
H
V
L
FGH
K
R
L
A
V
V
D
I--E--GGRQ
P
M
A
C
T
YKG
D
T
Y
T
I
I
YNGELY
N
T
E
D
L
R
K
E
L
R
AR-GHQFERTS
D
T
E
V
L
L
H
S
Y
I
----
E
---
W
-
Q
------
E
-----------------
D
-----------
C
V
D
H
L
N
G
I
F
A
F
A
V
WDEKR-
N
L
L
F
A
ARDRLGVK
P
F
F
--
Y
TK-EG-----S-SFL
F
G
S
E
I
K
A
I
LAHPDI
K
A
R
VDRT
G
L
S
E
I
FGLGPSRTP
G
T
G
I
F
K
G
I
K
E
IRPA
H
A
L
T
---FSKD--G--
L
N
I
W
R
Y
WNVESEK--HTD------SF
D
-----
D
T
V
A
N
---
V
R
S
L
F
Q
D
A
V
T
R
Q
L
V
-
S
DV
P
V
C
T
F
LSGGL
D
S
S
A
I
T
A
I
----AAGHFEKEGKAP
L
H
T
Y
S
IDYEEND
K
Y
F
QASAFQPNDDG
P
W
I
E
K
M
T
E
A
FGTT
H
H
K
C
VI
S
Q
K
D
L
V
D
H
L
E
E
A
V
L
V
KDL--P--GM--
A
D
V
D
S
S
--
L
--
L
W
F
C
R
E
I
K
K
-
D
-
F
V
-VSLSG
E
C
A
D
E
I
FGGYPW
F
H
TADVESGFPWMR
S
T
E
E
R
I
K
L
L
S
D
S
W
Q
KKL
N
L
K
E
Y
V
N
A
K
Y
E
E
T
L
AETPLLDGET
G
V
D
K
A
R
R
Q
L
F
Y
L
N
M
L
W
F
M
T
N
L
LD
R
K
D
R
MSMG
A
S
L
E
V
R
VPFAD
H
R
L
V
E
Y
V
WNI
P
W
E
M
KMHDN-
R
E
K
G
I
L
R
K
A
L
E
--GILP
D
D
I
LYRKKSPYPKTH
H
P
E
Y
T
K
G
V
S
-
E
W
L
K
T
I
R
SQ
K
D
S
V
--------------
L
H
T
L
L
D
R
K
Q
L
D
Q
L
L
E
TEGSSFKV
P
W
F
G
Q
LMK
G
P
Q
L
I
A
H
L
A
Q
I
H
T
W
F
E
A
Y
R
IDIDER
1
PsiBlast_PDB
96.81
26%
0
- C- -
1CT9
7
ASNB_ECOLI
A:
[1-486]
------
A
S
I
F
G
V
F
D
I
K
T
D
A
V
E
L
R
K
K
A
L
E
L
S
R
L
M
R
H
R
G
P
D
W
S
G
I
Y
--
A
S
----------------------------
D
N
A
I
L
A
H
E
R
L
S
I
V
D
V
--
N
--
A
G
A
Q
P
L
Y
N
Q
Q
K
--
T
H
V
L
A
V
N
G
E
I
Y
N
H
Q
A
L
R
A
E
Y
G
D
R
--
Y
Q
F
Q
T
G
S
D
C
E
V
I
L
A
L
Y
Q
----
E
---
K
-
G
------
P
-----------------
E
-----------
F
L
D
D
L
Q
G
M
F
A
F
A
L
Y
D
S
E
K
-
D
A
Y
L
I
G
R
D
H
L
G
I
I
P
L
Y
M
G
Y
D
E
-
H
G
-----
Q
-
L
Y
V
-
A
S
E
M
K
A
L
V
P
----------------------------
V
C
R
T
I
K
E
F
-
P
A
G
S
Y
L
---
W
S
Q
D
--
G
---------
E
I
R
S
Y
Y
--
H
R
D
------
W
F
D
YDAVK
D
N
V
T
D
K
N
E
L
R
Q
A
L
E
D
S
V
K
S
H
L
M
-
S
D
V
P
Y
G
V
L
L
S
G
G
L
D
S
S
I
I
S
A
I
T
K
K
Y
A
-----------
L
H
S
F
A
V
------------
G
L
P
G
S
P
D
L
K
A
A
Q
E
V
A
N
H
L
G
T
V
H
H
E
I
H
F
T
V
Q
E
G
L
D
A
I
R
D
V
I
Y
H
I
E
T
--
Y
--
D
V
--
T
T
I
R
A
S
T
P
M
--
Y
L
M
S
R
K
I
K
A
-
M
-
G
I
K
M
V
L
S
G
E
G
S
D
E
V
F
G
G
Y
L
Y
F
H
K
A
P
--------------------------
N
A
K
E
L
----
H
E
E
T
V
----------------
R
K
L
L
A
L
H
M
Y
-----
D
C
A
R
A
N
K
A
M
S
A
W
G
V
E
A
R
V
P
F
L
D
K
K
F
L
D
V
A
M
R
I
N
P
Q
D
K
M
C
--K
M
E
K
H
I
L
R
E
C
F
E
--
A
Y
L
P
A
S
V
A
W
R
Q
K
E
--------
Q
F
S
D
G
V
G
Y
S
W
I
D
T
L
K
E
----------------------
V
A
A
Q
Q
V
S
D
Q
Q
L
E
T
--
A
R
F
R
F
P
Y
-------------------------------
49
Fugue
95.30
26%
0
- C- -
1CT9
7
ASNB_ECOLI
A:
[1-516]
------
A
S
I
F
G
V
F
D
I
K
T
D
A
V
E
L
R
K
K
A
L
E
L
S
R
L
M
R
H
R
G
P
D
W
S
G
I
Y
--
A
S
----------------------------
D
N
A
I
L
A
H
E
R
L
S
I
V
D
V
--
N
--
A
G
A
Q
P
L
Y
--
N
Q
Q
K
T
H
V
L
A
V
N
G
E
I
Y
N
H
Q
A
L
R
A
E
Y
G
D
--
R
Y
Q
F
Q
T
G
S
D
C
E
V
I
L
A
L
Y
Q
----
E
---
K
-
G
------
P
-----------------
E
-----------
F
L
D
D
L
Q
G
M
F
A
F
A
L
Y
D
S
E
K
-
D
A
Y
L
I
G
R
D
H
L
G
I
I
P
L
Y
--
M
G
Y
D
E
H
-----
G
-
Q
L
Y
V
A
S
E
M
K
A
L
V
P
V
C
----------------------------
R
T
I
K
E
F
P
A
G
S
Y
L
W
---
S
Q
D
G
--
E
--
I
R
S
Y
Y
H
R
D
W
F
D
Y
D
--
A
V
K
------
D
N
V
-----
T
D
K
N
E
---
L
R
Q
A
L
E
D
S
V
K
S
H
L
M
-
S
D
V
P
Y
G
V
L
L
S
G
G
L
D
S
S
I
I
S
A
I
----
T
K
K
Y
-------
A
L
H
S
F
A
V
G
L
P
G
S
------------
P
D
L
K
A
A
Q
E
V
A
N
H
L
G
T
V
H
H
E
I
H
F
T
V
Q
E
G
L
D
A
I
R
D
V
I
Y
H
I
E
T
--
Y
--
D
V
--
T
T
I
R
A
S
--
T
P
M
Y
L
M
S
R
K
I
K
A
-
M
G
I
K
-
M
V
L
S
G
E
G
S
D
E
V
F
G
G
Y
L
Y
F
H
K
A
P
----------------------------------------------
N
A
K
E
L
H
E
E
T
V
R
K
L
L
A
L
H
M
-----
Y
D
C
A
R
A
N
K
A
M
S
A
W
G
V
E
A
R
V
P
F
L
D
K
K
F
L
D
V
A
M
R
I
N
P
Q
D
K
M
C
-
K
-
M
E
K
H
I
L
R
E
C
F
E
--
A
Y
L
P
A
S
V
A
W
R
Q
K
E
Q
F
S
D
G
V
G
Y
S
W
I
D
T
L
K
-
E
V
A
A
Q
Q
V
S
D
Q
Q
L
E
--------------
T
---
A
R
F
R
F
P
Y
N
T
P
T
S
K
E
A
Y
L
Y
R
E
I
F
E
E
L
F
P
L
P
S
A
A
E
C
V
P
G
---------------
48
Fugue
93.14
26%
0
- C- -
1CT9
7
ASNB_ECOLI
A:
[1-516]
------
A
S
I
F
G
V
F
D
I
K
T
D
A
V
E
L
R
K
K
A
L
E
L
S
R
L
M
R
H
R
G
P
D
W
S
G
I
Y
A
S
-
D
----------------------------
N
-
A
I
L
A
H
E
R
L
S
I
V
D
V
--
N
--
A
G
A
Q
P
L
Y
-
N
Q
Q
K
-
T
H
V
L
A
V
N
G
E
I
Y
N
H
Q
A
L
R
A
E
Y
G
-
D
-
R
Y
Q
F
Q
T
G
S
D
C
E
V
I
L
A
L
Y
Q
----
E
---
K
-
G
------
P
-----------------
E
-----------
F
L
D
D
L
Q
G
M
F
A
F
A
L
Y
D
S
E
K
-
D
A
Y
L
I
G
R
D
H
L
G
I
I
P
L
Y
--
M
G
Y
-
D
E
-----
H
G
Q
L
Y
V
A
S
E
M
K
A
L
V
P
V
C
R
----------------------------
T
I
K
E
F
P
A
G
S
Y
L
W
-----
S
Q
--
D
G--
E
I
R
S
Y
Y
H
R
D
W
F
D
--
Y
D
A
VKD
N
V
T
D
---------
K
N
E
---
L
R
Q
A
L
E
D
S
V
K
S
H
L
M
-
S
D
V
P
Y
G
V
L
L
S
G
G
L
D
S
S
I
I
S
A
I
----
T
K
K
Y
A
-------
L
H
S
F
A
V
G
L
P
G
S
------------
P
D
L
K
A
A
Q
E
V
A
N
H
L
G
T
V
H
H
E
I
H
F
T
V
Q
E
G
L
D
A
I
R
D
V
I
Y
H
I
E
T
YD
V
--
T
T
--
I
R
A
S
T
P
--
M
--
Y
L
M
S
R
K
I
K
A
-
M
-
G
I
K
M
V
L
S
G
E
G
S
D
E
V
F
G
G
Y
L
Y
F
H
K
-------------
A
P
N
A
K
E
L
H
E
E
T
V
R
K
L
L
A
L
H
M
--------------------------------------
Y
D
C
A
R
A
N
K
A
M
S
A
W
G
V
E
A
R
V
P
F
L
D
K
K
F
L
D
V
A
M
R
I
N
P
Q
D
K
M
C
K
--
M
E
K
H
I
L
R
E
C
F
E
--
A
Y
L
P
A
S
V
A
W
R
Q
K
E
Q
F
S
D
G
V
G
Y
S
W
I
D
T
L
K
-
E
V
A
A
Q
Q
-
V
S
D
Q
Q
L
--------------
E
T
--
A
R
F
R
F
P
Y
N
T
P
T
S
K
E
A
Y
L
Y
R
E
I
F
E
E
L
F
P
-------------
L
P
S
A
A
E
C
V
P
G
--
22
HHSearch
92.61
29%
0
- C- -
1CT9
7
ASNB_ECOLI
A:
[1-456]
------
A
S
I
F
G
V
F
D
I
K
T
D
A
V
E
L
R
K
K
A
L
E
L
S
R
L
M
R
H
R
G
P
D
W
S
G
I
Y
--
A
S
----------------------------
D
N
A
I
L
A
H
E
R
L
S
I
V
D
V
--
N
--
A
G
A
Q
P
L
Y
N
Q
Q
--
K
T
H
V
L
A
V
N
G
E
I
Y
N
H
Q
A
L
R
A
E
Y
G
D
R
--
Y
Q
F
Q
T
G
S
D
C
E
V
I
L
A
L
Y
Q
----
E
---
K
-
G
------
P
-----------------
E
-----------
F
L
D
D
L
Q
G
M
F
A
F
A
L
Y
D
S
E
K
-
D
A
Y
L
I
G
R
D
H
L
G
I
I
P
L
Y
--
M
G
Y
-
D
E
H----
G
-
Q
L
Y
V
A
S
E
M
K
A
L
V
P
V
----------------------------
C
R
T
I
K
E
F
P
A
G
S
Y
L
W
---
S
Q
D
G
--
E
----
I
R
S
Y
Y
H
R
D
W
F
D
YD
A
V
K
------
D
N
V
-----
T
D
K
N
E
---
L
R
Q
A
L
E
D
S
V
K
S
H
L
M
-
S
D
V
P
Y
G
V
L
L
S
G
G
L
D
S
S
I
I
S
A
I
----
T
K
K
Y
A
-------
L
H
S
F
A
V
G
L
P
------------
G
S
P
D
L
K
A
A
Q
E
V
A
N
H
L
G
T
V
H
H
E
I
H
F
T
V
Q
E
G
L
D
A
I
R
D
V
I
Y
H
I
E
T
--
Y
--
D
V
T
T
I
R
A
S
T
P
--
M
--
Y
L
M
S
R
K
I
K
A
M
G
-
I
K
-
M
V
L
S
G
E
G
S
D
E
V
F
G
G
Y
L
Y
F
H
K
A
-----
P
N
A
K
E
-------
L
H
-----
E
E
-------------
T
V
R
K
---
L
----------
L
A
L
H
--------
M
Y
D
C
A
R
A
N
K
A
M
S
A
W
G
V
E
A
R
V
P
F
L
D
K
K
F
L
D
V
A
M
R
I
N
P
Q
D
K
M
C
-
K
-
M
E
K
H
I
L
R
E
C
F
E
--
A
Y
L
P
A
S
V
A
W
R
Q
K
E
Q
F
S
D
G
V
---------------------------------------------------------------------------------------------
47
Fugue
69.39
18%
-70
* C4 *
1JGT
4
BLS_STRCL
A:
[4-508]
PVLPA
A
F
G
F
L
A
S
A
R
--------
T
G
G
G
P
V
F
A
T
R
G
S
H
T
D
I
D
T
P
Q
G
E
--
R
S
----------------------------
L
A
A
T
L
V
H
A
P
S
V
A
P
D
R
--
A
---
V
A
R
S
L
----
T
G
A
P
T
T
A
V
L
A
G
E
I
Y
N
R
D
E
L
L
S
V
L
----
P
A
G
P
A
P
E
G
D
A
E
L
V
L
R
L
L
E
----
R
---
Y
-
D
------
L
-----------------
H
-----------
A
F
R
L
V
N
G
R
F
A
T
V
V
R
T
--
G
-
D
R
V
L
L
A
T
D
H
A
G
S
V
P
L
Y
--
T
C
V
-
A
P
-----
G
-
E
V
R
A
S
T
E
A
K
A
L
A
A
H
P
K
G
F
P
L
A
D
A
R
R
V
A
--------------
G
L
T
G
V
Y
Q
V
P
A
G
A
V
M
D
---
I
D
L
G
--
S
G
T
A
V
T
H
R
T
W
T
P
G
L
S
R
--
R
I
L
------
P
E
G
-----
E
A
V
A
A
---
V
R
A
A
L
E
K
A
V
A
Q
R
V
T
-
P
G
D
T
P
L
V
V
L
S
G
G
I
D
S
S
G
V
A
A
C
----
A
H
R
A
A
G
-----
E
L
D
T
V
S
M
G
------------
T
D
T
S
N
E
F
R
E
A
R
A
V
V
D
H
L
R
T
R
H
R
E
I
T
I
P
T
T
E
L
L
A
Q
L
P
Y
A
V
W
A
S
E
S
VD
P
--
D
I
--
I
E
Y
L
L
P
--
L
--
T
A
L
Y
R
A
L
D
G
-
P
-
E
R
-
R
I
L
T
G
Y
G
A
D
I
P
L
G
G
M
H
R
E
D
R
L
------------------------------
P
A
L
D
T
V
L
A
H
D
M
A
T
-------------------------
F
D
G
L
N
E
M
S
P
V
L
S
T
L
A
G
H
W
T
T
H
P
Y
W
D
R
E
V
L
D
L
L
V
S
L
E
A
G
L
K
R
R
H
G
-
R
D
K
W
V
L
R
A
A
M
A
--
D
A
L
P
A
E
T
V
N
R
P
K
L
--------------
S
-
S
F
S
R
L
L
L
D
H
G
V
A
E
--------------
D
R
V
H
E
A
K
R
Q
V
V
R
E
L
F
D
L
T
V
G
G
G
R
H
--------
P
S
E
V
-------
D
T
D
D
V
V
R
S
V
A
D
R
T
50
Fugue
66.60
17%
-69
- C4 -
1Q19
3
CARA_PECCC
A:
[2-501]
---------------
S
N
S
F
C
V
V
Y
K
G
S
D
T
D
I
N
N
I
Q
R
D
F
D
G
--------------------------------------
K
G
E
A
L
S
N
G
Y
L
F
I
E
Q
--
N
--
G
H
Y
Q
K
C
E
----
M
E
R
G
T
A
Y
L
I
G
S
L
Y
N
R
T
F
L
I
G
L
A
G
V
W
-
E
G
E
A
Y
L
A
N
D
A
E
L
L
A
L
L
F
T
----
R
---
L
-
G
------
A
-----------------
N
-----------
A
L
A
L
A
E
G
D
F
C
F
F
I
D
E
P
N
G
-
E
-
L
T
V
I
T
E
S
R
G
F
S
P
V
H
--
V
V
Q
-
G
K
-----
K
-
A
W
M
T
N
S
L
K
L
V
T
A
A
E
G
E
G
A
L
W
F
E
E
E
A
L
V
C
Q
S
L
M
R
A
D
T
Y
T
---
P
V
K
N
A
Q
R
L
K
P
G
A
V
H
V
---
L
T
H
D
SE
G
--
Y
S
F
V
E
S
R
T
L
T
T
P
A
--
S
N
Q
LLAL--
P
R
E
-----
P
L
L
A
L
---
I
D
R
Y
L
N
A
P
L
E
D
L
A
P
-
R
F
D
T
V
G
I
P
L
S
G
G
L
D
S
S
L
V
T
A
L
----
A
S
R
H
F
K
-----
K
L
N
T
Y
S
I
G
T
E
------------
L
S
N
E
F
E
F
S
Q
Q
V
A
D
A
L
G
T
H
H
Q
M
K
I
L
S
E
T
E
V
I
N
G
I
I
E
S
I
Y
Y
N
E
I
--
F
D
G
L
S
--
A
E
I
Q
S
G
--
L
--
F
N
V
Y
R
Q
A
Q
G
-
Q
-
V
S
-
C
M
L
T
G
Y
G
S
D
L
L
F
G
G
I
L
K
P
G
A
Q
Y
------------------------------------------------------
D
N
P
N
Q
L
L
A
E
Q
V
Y
R
T
R
W
T
G
E
F
A
T
H
G
A
S
C
Y
G
I
D
I
R
H
P
F
W
S
H
S
L
I
S
L
C
H
A
L
H
P
D
Y
K
I
F
D
N
-
E
V
K
N
I
L
R
E
Y
A
D
S
L
Q
L
L
P
K
D
I
V
W
R
K
K
I
G
I
H
E
G
-----
S
S
V
N
Q
-
A
F
A
N
V
L
G
S
T
V
D
N
-----------------------------
Y
Q
T
K
S
R
F
T
Y
R
V
Y
Q
A
F
L
R
G
R
L
S
I
T
D
V
-------
T
P
S
Q
L
K
D
L
I
K
51
Fugue
54.82
25%
0
- C- -
1CT9
6
ASNB_ECOLI
A:
[193-516]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
D
W
F
D
Y
D
A
V
--
K
D
N
------
V
-------
T
D
K
N
E
---
L
R
Q
A
L
E
D
S
V
K
S
H
L
M
-
S
D
V
P
Y
G
V
L
L
S
G
G
L
D
S
S
I
I
S
A
I
----
T
K
K
Y
A
-------
L
H
S
F
A
V
G
L
P
G
S
------------
P
D
L
K
A
A
Q
E
V
A
N
H
L
G
T
V
H
H
E
I
H
F
T
V
Q
E
G
L
D
A
I
R
D
V
I
Y
H
I
E
T
--
Y
--
D
V
--
T
T
I
R
A
S
--
T
P
M
Y
L
M
S
R
K
I
K
A
-
M
-
G
I
K
M
V
L
S
G
E
G
S
D
E
V
F
G
G
Y
L
Y
F
H
K
A
P
--
N
A
K
E
L
H
E
E
T
V
R
K
L
L
A
L
H
M
-------------------------------------------------
Y
D
C
A
R
A
N
K
A
M
S
A
W
G
V
E
A
R
V
P
F
L
D
K
K
F
L
D
V
A
M
R
I
N
P
Q
D
K
M
C
K
--
M
E
K
H
I
L
R
E
C
F
E
--
A
Y
L
P
A
S
V
A
W
R
Q
K
E
Q
F
S
D
G
V
G
Y
S
W
I
D
T
L
K
-
E
V
A
A
Q
Q
-
V
S
D
Q
Q
L
E
T
ARFRFPYNTPTS
K
E
A
Y
L
Y
R
E
I
F
E
E
L
F
P
---------
L
P
S
A
A
E
C
V
P
G
----------------------
8
PsiBlast_PDB
53.57
25%
-107
- C3 -
1MC1
4
BLS_STRCL
A:
[62-313]
-----------------------------------------------------------------------------------------------------
V
A
R
S
L
T
G
A
P
T
T
A
V
L
A
G
E
I
Y
N
R
D
E
L
L
S
V
L
P
A
--
G
P
A
P
E
--
G
D
A
E
L
V
L
R
L
L
E
----
R
---
Y
-
D
------
L
-----------------
H
-----------
A
F
R
L
V
N
G
R
F
A
T
V
V
R
T
G
D
R
-
V
L
L
--
A
T
D
H
A
G
S
V
P
L
Y
--
T
C
V
-
A
P
-----
G
-
E
V
R
A
S
T
E
A
K
A
L
A
A
-----
G
----------
F
P
L
A
D
A
R
R
--
V
A
G
L
T
G
V
Y
Q
V
-
P
A
G
A
V
M
D
I
D
L
G
S
G
--
T
--
A
V
T
H
R
T
W
T
P
G
L
S
R
--
R
I
L
------
P
E
G
-----
E
A
V
A
A
---
V
R
A
A
L
E
K
A
V
A
Q
R
V
T
P
G
D
T
P
L
V
-
V
L
S
G
G
I
D
S
S
G
V
A
A
C
----
A
-----
H
R
A
A
G
E
L
D
T
V
S
M
G
T
D
T
S
N
E
F
R
E
A
R
A
------------
V
V
D
H
L
R
T
R
H
R
E
I
T
I
P
T
T
E
L
L
A
Q
L
P
Y
A
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
52.56
25%
-109
- C3 -
1MB9
2
BLS_STRCL
A:
[62-323]
-----------------------------------------------------------------------------------------------------
V
A
R
S
L
T
G
A
P
T
T
A
V
L
A
G
E
I
Y
N
R
D
E
L
L
S
V
L
P
A
--
G
P
A
P
E
--
G
D
A
E
L
V
L
R
L
L
E
----
R
---
Y
-
D
------
L
-----------------
H
-----------
A
F
R
L
V
N
G
R
F
A
T
V
V
R
T
G
D
R
-
V
L
L
--
A
T
D
H
A
G
S
V
P
L
Y
--
T
C
V
-
A
P
-----
G
-
E
V
R
A
S
T
E
A
K
A
L
A
A
----------------
F
P
L
A
D
A
R
R
--
V
A
G
L
T
G
V
Y
Q
V
-
P
A
G
A
V
M
D
I
D
L
G
S
G
--
T
--
A
V
T
H
R
T
W
T
P
G
L
S
R
--
R
I
L
------
P
E
G
-----
E
A
V
A
A
---
V
R
A
A
L
E
K
A
V
A
Q
R
V
T
P
G
D
T
P
L
V
-
V
L
S
G
G
I
D
S
S
G
V
A
A
C
----
A
-----
H
R
A
A
G
E
L
D
T
V
S
M
G
T
D
T
S
N
E
F
R
E
A
R
A
------------
V
V
D
H
L
R
T
R
H
R
E
I
T
I
P
T
T
E
L
L
A
Q
L
P
Y
A
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
51.91
25%
-107
- C3 -
1M1Z
-
BLS_STRCL
A:
[62-328]
-----------------------------------------------------------------------------------------------------
V
A
R
S
L
T
G
A
P
T
T
A
V
L
A
G
E
I
Y
N
R
D
E
L
L
S
V
L
P
A
--
G
P
A
P
E
--
G
D
A
E
L
V
L
R
L
L
E
----
R
---
Y
-
D
------
L
-----------------
H
-----------
A
F
R
L
V
N
G
R
F
A
T
V
V
R
T
G
D
R
-
V
L
L
--
A
T
D
H
A
G
S
V
P
L
Y
--
T
C
V
-
A
P
-----
G
-
E
V
R
A
S
T
E
A
K
A
L
A
A
H
---------------
F
P
L
A
D
A
R
R
--
V
A
G
L
T
G
V
Y
Q
V
-
P
A
G
A
V
M
D
I
D
L
G
S
G
--
T
--
A
V
T
H
R
T
W
T
P
G
L
S
R
--
R
I
L
------
P
E
G
-----
E
A
V
A
A
---
V
R
A
A
L
E
K
A
V
A
Q
R
V
T
P
G
D
T
P
L
V
-
V
L
S
G
G
I
D
S
S
G
V
A
A
C
----
A
-----
H
R
A
A
G
E
L
D
T
V
S
M
G
T
D
T
S
N
E
F
R
E
A
R
A
------------
V
V
D
H
L
R
T
R
H
R
E
I
T
I
P
T
T
E
L
L
A
Q
L
P
Y
A
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
51.44
25%
-103
- C3 -
1MBZ
4
BLS_STRCL
A:
[62-313]
-----------------------------------------------------------------------------------------------------
V
A
R
S
L
T
G
A
P
T
T
A
V
L
A
G
E
I
Y
N
R
D
E
L
L
S
V
L
P
A
--
G
P
A
P
E
--
G
D
A
E
L
V
L
R
L
L
E
----
R
---
Y
-
D
------
L
-----------------
H
-----------
A
F
R
L
V
N
G
R
F
A
T
V
V
R
T
G
D
R
-
V
L
L
--
A
T
D
H
A
G
S
V
P
L
Y
--
T
C
V
-
A
P
-----
G
-
E
V
R
A
S
T
E
A
K
A
L
A
A
H
----
G
----------
F
P
L
A
D
A
R
R
--
V
A
G
L
T
G
V
Y
Q
V
-
P
A
G
A
V
M
D
I
D
L
G
S
G
--
T
--
A
V
T
H
R
T
W
T
P
G
L
S
R
--
R
I
L
------
P
E
G
-----
E
A
V
A
A
---
V
R
A
A
L
E
K
A
V
A
Q
R
V
T
P
G
D
T
P
L
V
-
V
L
S
G
G
I
D
S
S
G
V
A
A
C
----
A
-----
H
R
A
A
G
E
L
D
T
V
S
M
G
T
D
T
S
N
E
F
R
E
A
R
A
------------
V
V
D
H
L
R
T
R
H
R
E
I
T
I
P
T
T
E
L
L
A
Q
L
P
Y
A
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
51.15
24%
-106
- C3 -
1ECF
2
PUR1_ECOLI
A:
[1-245]
------
C
G
I
V
G
I
A
G
V
M
P
V
N
----
Q
S
I
Y
D
A
L
T
V
L
Q
H
R
G
Q
D
A
A
G
I
I
--
T
I
D
ANN
C
F
R
L
R
K
A
N
G
L
V
S
D
V
F
E
A
R
H
M
Q
R
LQ
G
N
M
G
I
G
H
V
R
Y
P
T
A
G
S
--
S
SA
S
E
A
Q
P
F
Y
V
N
S
P
-
Y
G
I
T
L
A
H
N
G
N
L
T
N
A
H
E
L
R
K
K
L
F
E
E
K
R
R
H
I
N
T
T
S
D
S
E
I
L
L
N
I
F
A
----
S
---
E
-
L
------
D
NFRHYPLE
A
D
N
I
F
A
A
I
A
A
-----------
T
N
R
L
I
R
G
A
Y
A
C
V
A
M
I
I
G
--
H
G
M
V
A
F
R
D
P
N
G
I
R
P
L
V
--
L
G
K
-
R
D
IDEN
R
T
-
E
Y
M
V
A
S
E
S
V
A
L
D
T
L
------------------
G
---------
F
D
F
L
R
D
V
A
P
G
E
A
I
Y
---
I
T
E
E
--
G
--
Q
L
F
T
R
Q
C
A
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
50.67
25%
-102
- C3 -
1JGT
2
BLS_STRCL
A:
[62-322]
-----------------------------------------------------------------------------------------------------
V
A
R
S
L
T
G
A
P
T
T
A
V
L
A
G
E
I
Y
N
R
D
E
L
L
S
V
L
P
A
--
G
P
A
P
E
--
G
D
A
E
L
V
L
R
L
L
E
----
R
---
Y
-
D
------
L
-----------------
H
-----------
A
F
R
L
V
N
G
R
F
A
T
V
V
R
T
G
D
R
-
V
L
L
--
A
T
D
H
A
G
S
V
P
L
Y
--
T
C
V
-
A
P
-----
G
-
E
V
R
A
S
T
E
A
K
A
L
A
A
H
--
P
K
G
----------
F
P
L
A
D
A
R
R
--
V
A
G
L
T
G
V
Y
Q
V
-
P
A
G
A
V
M
D
I
D
L
G
S
G
--
T
--
A
V
T
H
R
T
W
T
P
G
L
S
R
--
R
I
L
------
P
E
G
-----
E
A
V
A
A
---
V
R
A
A
L
E
K
A
V
A
Q
R
V
T
P
G
D
T
P
L
V
-
V
L
S
G
G
I
D
S
S
G
V
A
A
C
----
A
-----
H
R
A
A
G
E
L
D
T
V
S
M
G
T
D
T
S
N
E
F
R
E
A
R
A
------------
V
V
D
H
L
R
T
R
H
R
E
I
T
I
P
T
T
E
L
L
A
Q
L
P
Y
A
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
49.48
23%
-104
- C3 -
1XFF
3
GLMS_ECOLI
A:
[1-220]
------
C
G
I
V
G
A
I
A
Q
R
D
V
----
A
E
I
L
L
E
G
L
R
R
L
E
Y
R
G
Y
D
S
A
G
L
A
--
V
V
D
AEG
H
M
T
R
L
R
R
LGK
V
Q
M
L
A
Q
A
A
E
E
H
PLH
G
G
T
G
I
A
H
T
R
W
A
T
H
G
E
PS
E
--
V
N
A
H
P
H
V
S
E
----
H
I
V
V
V
H
N
G
I
I
E
N
H
E
P
L
R
E
E
L
K
A
R
-
G
Y
T
F
V
S
E
T
D
T
E
V
I
A
H
L
V
N
----
W
E
L
K
Q
G
G
T
L
R
E
A
V
L
-----------------
R
-----------
A
I
P
Q
L
R
G
A
Y
G
T
V
I
M
D
S
R
H
P
D
T
L
L
A
A
R
S
G
---
S
P
L
V
--
I
G
L
-
G
M
-----
G
-
E
N
F
I
A
S
D
Q
L
A
L
L
P
V
T
----------------------------
R
R
F
I
F
L
E
E
G
D
I
A
E
---
I
T
R
R
--
S
--
V
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
49.02
30%
-203
- C3 -
3OOJ
1
GLMS_ECOLI
A:
[94-173]
---------------------------------------------------------------------------------------------------------------
V
V
V
H
N
G
I
I
E
N
H
E
P
L
R
E
E
L
K
A
R
-
G
Y
T
F
V
S
E
T
D
T
E
V
I
A
H
-
L
V
----
N
---
W
-
E
------
L
-----------------
K
QGGT
L
R
E
A
V
L
R
A
I
P
Q
L
R
G
A
Y
G
T
V
I
M
D
S
R
H
P
D
T
L
L
A
A
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
48.72
30%
-168
- C3 -
1XFG
3
GLMS_ECOLI
A:
[94-174]
---------------------------------------------------------------------------------------------------------------
V
V
V
H
N
G
I
I
E
N
H
E
P
L
R
E
E
L
K
A
R
-
G
Y
T
F
V
S
E
T
D
T
E
V
I
A
H
-
L
V
----
N
---
W
-
E
------
L
-----------------
K
Q
GGT
L
R
E
A
V
L
R
A
I
P
Q
L
R
G
A
Y
G
T
V
I
M
D
S
R
H
P
D
T
L
L
A
A
R
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
48.65
30%
-191
- C3 -
2J6H
1
GLMS_ECOLI
A:
[94-173]
---------------------------------------------------------------------------------------------------------------
V
V
V
H
N
G
I
I
E
N
H
E
P
L
R
E
E
L
K
A
R
-
G
Y
T
F
V
S
E
T
D
T
E
V
I
A
H
-
L
V
----
N
---
W
-
E
------
L
-----------------
K
Q
GGT
L
R
E
A
V
L
R
A
I
P
Q
L
R
G
A
Y
G
T
V
I
M
D
S
R
H
P
D
T
L
L
A
A
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
47.83
30%
-178
- C3 -
1XFF
3
GLMS_ECOLI
A:
[94-174]
---------------------------------------------------------------------------------------------------------------
V
V
V
H
N
G
I
I
E
N
H
E
P
L
R
E
E
L
K
A
R
-
G
Y
T
F
V
S
E
T
D
T
E
V
I
A
H
-
L
V
----
N
---
W
-
E
------
L
-----------------
K
Q
GGT
L
R
E
A
V
L
R
A
I
P
Q
L
R
G
A
Y
G
T
V
I
M
D
S
R
H
P
D
T
L
L
A
A
R
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
46.96
30%
-190
- C3 -
4AMV
-
GLMS_ECOLI
A:
[95-174]
---------------------------------------------------------------------------------------------------------------
V
V
V
H
N
G
I
I
E
N
H
E
P
L
R
E
E
L
K
A
R
-
G
Y
T
F
V
S
E
T
D
T
E
V
I
A
H
-
L
V
----
N
---
W
-
E
------
L
-----------------
K
QGGT
L
R
E
A
V
L
R
A
I
P
Q
L
R
G
A
Y
G
T
V
I
M
D
S
R
H
P
D
T
L
L
A
A
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
46.03
26%
-102
- C3 -
4AMV
-
GLMS_ECOLI
A:
[2-200]
------
C
G
I
V
G
A
I
A
Q
R
D
V
----
A
E
I
L
L
E
G
L
R
R
L
E
Y
R
G
Y
D
S
A
G
L
A
--
V
V
D
AEGH
M
T
R
L
R
R
L
G
K
V
Q
M
L
A
Q
A
A
E
E
H
P
L
H
G
G
T
G
I
A
H
T
R
W
A
T
H
G
E
--
P
SE
V
N
A
H
P
H
V
S
E
----
H
I
V
V
V
H
N
G
I
I
E
N
H
E
P
L
R
E
E
L
K
A
R
-
G
Y
T
F
V
S
E
T
D
T
E
V
I
A
H
L
V
N
W
E
L
K
Q
---
G
-
G
T
L
R
E
A
V
L
-----------------
R
-----------
A
I
P
Q
L
R
G
A
Y
G
T
V
I
M
D
S
R
H
P
D
T
L
L
A
A
R
S
G
---
S
P
L
V
--
I
G
L
-
G
M
-----
G
-
E
N
F
I
A
S
D
Q
L
A
L
L
P
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------