@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu10930: (2016-06-17 )
MNETITYDTWNDMLSKQITDQLIDELDVLKWAYRTYGEKIVYACSFGAEGMVLLDLISKINKNAHIIFLDTGLHFQETYELIETVKERYPGFAIQMLEPELSLTEQGTKYGGELWKHNPNLCCQLRKIEPLKKHLSGMTAWISGLRRDQSPTRKHIQYVNLDQKFELIKICPLIHWTWDDVWTYIRLHNLPYNKLHDQHYPSIGCEMCTLPSPDPNDERAGRWAGREKTECGLHQE
Atome Classification :
(20 SA)
-----------------.........10....-....20.......---.30.----.......40........50........60---.----....-----....70........80........---90........100--....--.--..110--..-.-....120..---.....130....--..--.140.........150.-.......160-----------------------...-.-----...170.......180.......190.....--..200.......210.-----.-------------.....220.......230....-----------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------MNE
T
I
T
Y
D
T
W
N
D
M
L
S
-
K
Q
I
T
D
Q
L
I
D
E
L
D
V
---
L
K
W
A
----
Y
R
TYG
E
K
I
V
Y
A
C
SFGAE
G
M
V
L
L
D
L
I
S
K
I----N----KN
A
H
-----
I
I
F
LDTGL
H
F
Q
E
T
Y
E
L
I
E
T
V
K
E
RY---PG
F
A
I
Q
M
LEPELS--LTEQ--
G
--
T
KYG
G
--
E
L
-W-KHNPN
L
C
C
Q
---LRK
I
E
P
L
K
K
H
L
S
--
G
M
--
T
A
--
W
I
S
G
L
RRDQSP-T-
R
K
H
I
Q
YVN
L
D
-----------------------
Q
K
F
-
E
-----
L
I
K
IC
P
L
I
H
W
T
W
D
D
V
W
T
Y
I
R
LHNLPY
N
K
LHD--QHYPSIGCEMCTLPSP-----D-------------P
N
D
E
R
A
GRWAGREKTECGLHQE-----------------------------------
40
HHSearch
87.92
39%
-114
- C3 -
2GOY
1
CYSH_PSEAE
A:
[28-249]
---------------------
F
D
L
P
A
L
A
S
S
L
A
-
D
------
K
S
P
Q
D
I
---
L
K
A
A
----
F
E
H
F
G
D
E
L
W
I
S
F
S
G
A
E
D
V
-
V
L
V
D
M
A
W
K
L
----
N
----
R
N
V
K
-----
V
F
S
L
D
T
G
R
L
H
P
E
T
Y
R
F
I
D
Q
V
R
E
H
Y
---
G
-
I
A
I
D
V
L
S
P
D
P
R
L
-
L
E
P
L
--
V
--
K
E
K
G
L
--
F
S
-
F
Y
R
D
G
H
G
E
C
C
G
---
I
R
K
I
E
P
L
K
R
K
L
A
--
G
V
--
R
A
--
W
A
T
G
Q
R
R
D
Q
S
P
-
G
T
R
S
Q
V
A
V
L
E
I
D
GAFST------------------
P
E
K
-
P
-----
L
Y
K
F
N
P
L
S
S
M
T
S
E
E
V
W
G
Y
I
R
M
L
E
L
P
Y
N
S
L
H
E
--
R
G
Y
I
S
I
G
C
E
P
C
T
R
P
V
L
-----
P
-------------
N
Q
H
E
R
E
G
R
W
W
W
E
---------------------------------------------
1
PsiBlast_PDB
85.97
44%
-109
- C3 -
2GOY
1
CYSH_PSEAE
A:
[44-249]
--------------------------------------------
D
I
---
L
K
A
A
----
F
E
H
F
G
D
E
L
W
I
S
F
S
-
G
A
E
D
V
V
L
V
D
M
A
W
K
L
----
N
----
R
N
V
K
-----
V
F
S
L
D
T
G
R
L
H
P
E
T
Y
R
F
I
D
Q
V
R
E
H
Y
----
G
I
A
I
D
V
L
S
P
D
P
R
--
L
L
E
P
--
L
--
V
K
E
K
G
LF
S
F
-
Y
-
R
D
G
H
G
E
C
C
G
---
I
R
K
I
E
P
L
K
R
K
L
A
--
G
V
--
R
A
--
W
A
T
G
Q
R
R
D
Q
S
P
G
T
-
R
S
Q
V
A
V
L
E
I
D
-----------------------
G
A
F
-
S
TPE
K
P
L
Y
K
F
N
P
L
S
S
M
T
S
E
E
V
W
G
Y
I
R
M
L
E
L
P
Y
N
S
L
H
E
--
R
G
Y
I
S
I
G
C
E
P
C
T
R
P
V
L
-----
P
-------------
N
Q
H
E
R
E
G
R
W
W
W
E
---------------------------------------------
23
PsiBlast_CBE
85.74
44%
-108
- C3 -
2GOY
2
CYSH_PSEAE
D:
[44-249]
--------------------------------------------
D
I
---
L
K
A
A
----
F
E
H
F
G
D
E
L
W
I
S
F
S
-
G
A
E
D
V
V
L
V
D
M
A
W
K
L
----
N
----
R
N
V
K
-----
V
F
S
L
D
T
G
R
L
H
P
E
T
Y
R
F
I
D
Q
V
R
E
H
Y
----
G
I
A
I
D
V
L
S
P
D
P
R
--
L
L
E
P
--
L
--
V
K
E
K
G
LF
S
F
-
Y
-
R
D
G
H
G
E
C
C
G
---
I
R
K
I
E
P
L
K
R
K
L
A
--
G
V
--
R
A
--
W
A
T
G
Q
R
R
D
Q
S
P
G
T
-
R
S
Q
V
A
V
L
E
I
D
-----------------------
G
A
F
-
S
TPEKP
L
Y
K
F
N
P
L
S
S
M
T
S
E
E
V
W
G
Y
I
R
M
L
E
L
P
Y
N
S
L
H
E
--
R
G
Y
I
S
I
G
C
E
P
C
T
R
P
V
L
-----
P
-------------
N
Q
H
E
R
E
G
R
W
W
W
E
---------------------------------------------
22
PsiBlast_CBE
85.31
44%
-113
- C3 -
2GOY
1
CYSH_PSEAE
E:
[44-249]
--------------------------------------------
D
I
---
L
K
A
A
----
F
E
H
F
G
D
E
L
W
I
S
F
S
-
G
A
E
D
V
V
L
V
D
M
A
W
K
L
----
N
----
R
N
V
K
-----
V
F
S
L
D
T
G
R
L
H
P
E
T
Y
R
F
I
D
Q
V
R
E
H
Y
----
G
I
A
I
D
V
L
S
P
D
P
R
--
L
L
E
P
--
L
--
V
K
E
K
G
LF
S
F
-
Y
-
R
D
G
H
G
E
C
C
G
---
I
R
K
I
E
P
L
K
R
K
L
A
--
G
V
--
R
A
--
W
A
T
G
Q
R
R
D
Q
S
P
G
T
-
R
S
Q
V
A
V
L
E
I
D
-----------------------
G
A
F
-
S
TPEKP
L
Y
K
F
N
P
L
S
S
M
T
S
E
E
V
W
G
Y
I
R
M
L
E
L
P
Y
N
S
L
H
E
--
R
G
Y
I
S
I
G
C
E
P
C
T
R
P
V
L
-----
P
-------------
N
Q
H
E
R
E
G
R
W
W
W
E
---------------------------------------------
20
PsiBlast_CBE
85.29
44%
-110
- C3 -
2GOY
1
CYSH_PSEAE
G:
[44-249]
--------------------------------------------
D
I
---
L
K
A
A
----
F
E
H
F
G
D
E
L
W
I
S
F
S
-
G
A
E
D
V
V
L
V
D
M
A
W
K
L
----
N
----
R
N
V
K
-----
V
F
S
L
D
T
G
R
L
H
P
E
T
Y
R
F
I
D
Q
V
R
E
H
Y
----
G
I
A
I
D
V
L
S
P
D
P
R
--
L
L
E
P
--
L
--
V
K
E
K
G
LF
S
F
-
Y
-
R
D
G
H
G
E
C
C
G
---
I
R
K
I
E
P
L
K
R
K
L
A
--
G
V
--
R
A
--
W
A
T
G
Q
R
R
D
Q
S
P
G
T
-
R
S
Q
V
A
V
L
E
I
D
-----------------------
G
A
F
-
S
TPEKP
L
Y
K
F
N
P
L
S
S
M
T
S
E
E
V
W
G
Y
I
R
M
L
E
L
P
Y
N
S
L
H
E
--
R
G
Y
I
S
I
G
C
E
P
C
T
R
P
V
L
-----
P
-------------
N
Q
H
E
R
E
G
R
W
W
W
E
---------------------------------------------
25
PsiBlast_CBE
84.51
44%
-104
- C3 -
2GOY
2
CYSH_PSEAE
B:
[44-249]
--------------------------------------------
D
I
---
L
K
A
A
----
F
E
H
F
G
D
E
L
W
I
S
F
S
-
G
A
E
D
V
V
L
V
D
M
A
W
K
L
----
N
----
R
N
V
K
-----
V
F
S
L
D
T
G
R
L
H
P
E
T
Y
R
F
I
D
Q
V
R
E
H
Y
----
G
I
A
I
D
V
L
S
P
D
P
R
--
L
L
E
P
--
L
--
V
K
E
K
G
LF
S
F
-
Y
-
R
D
G
H
G
E
C
C
G
---
I
R
K
I
E
P
L
K
R
K
L
A
--
G
V
--
R
A
--
W
A
T
G
Q
R
R
D
Q
S
P
G
T
-
R
S
Q
V
A
V
L
E
I
D
-----------------------
G
A
F
-
S
TPE
K
P
L
Y
K
F
N
P
L
S
S
M
T
S
E
E
V
W
G
Y
I
R
M
L
E
L
P
Y
N
S
L
H
E
--
R
G
Y
I
S
I
G
C
E
P
C
T
R
P
V
L
-----
P
-------------
N
Q
H
E
R
E
G
R
W
W
W
E
---------------------------------------------
24
PsiBlast_CBE
84.42
44%
-114
- C3 -
2GOY
1
CYSH_PSEAE
C:
[44-249]
--------------------------------------------
D
I
---
L
K
A
A
----
F
E
H
F
G
D
E
L
W
I
S
F
S
-
G
A
E
D
V
V
L
V
D
M
A
W
K
L
----
N
----
R
N
V
K
-----
V
F
S
L
D
T
G
R
L
H
P
E
T
Y
R
F
I
D
Q
V
R
E
H
Y
----
G
I
A
I
D
V
L
S
P
D
P
R
--
L
L
E
P
--
L
--
V
K
E
K
G
LF
S
F
-
Y
-
R
D
G
H
G
E
C
C
G
---
I
R
K
I
E
P
L
K
R
K
L
A
--
G
V
--
R
A
--
W
A
T
G
Q
R
R
D
Q
S
P
G
T
-
R
S
Q
V
A
V
L
E
I
D
-----------------------
G
A
F
-
S
TPEKP
L
Y
K
F
N
P
L
S
S
M
T
S
E
E
V
W
G
Y
I
R
M
L
E
L
P
Y
N
S
L
H
E
--
R
G
Y
I
S
I
G
C
E
P
C
T
R
P
V
L
-----
P
-------------
N
Q
H
E
R
E
G
R
W
W
W
E
---------------------------------------------
21
PsiBlast_CBE
84.02
44%
-104
- C3 -
2GOY
2
CYSH_PSEAE
F:
[44-249]
--------------------------------------------
D
I
---
L
K
A
A
----
F
E
H
F
G
D
E
L
W
I
S
F
S
-
G
A
E
D
V
V
L
V
D
M
A
W
K
L
----
N
----
R
N
V
K
-----
V
F
S
L
D
T
G
R
L
H
P
E
T
Y
R
F
I
D
Q
V
R
E
H
Y
----
G
I
A
I
D
V
L
S
P
D
P
R
--
L
L
E
P
--
L
--
V
K
E
K
G
LF
S
F
-
Y
-
R
D
G
H
G
E
C
C
G
---
I
R
K
I
E
P
L
K
R
K
L
A
--
G
V
--
R
A
--
W
A
T
G
Q
R
R
D
Q
S
P
G
T
-
R
S
Q
V
A
V
L
E
I
D
-----------------------
G
A
F
-
S
TPEKP
L
Y
K
F
N
P
L
S
S
M
T
S
E
E
V
W
G
Y
I
R
M
L
E
L
P
Y
N
S
L
H
E
--
R
G
Y
I
S
I
G
C
E
P
C
T
R
P
V
L
-----
P
-------------
N
Q
H
E
R
E
G
R
W
W
W
E
---------------------------------------------
19
PsiBlast_CBE
83.61
44%
-103
- C3 -
2GOY
2
CYSH_PSEAE
H:
[44-249]
--------------------------------------------
D
I
---
L
K
A
A
----
F
E
H
F
G
D
E
L
W
I
S
F
S
-
G
A
E
D
V
V
L
V
D
M
A
W
K
L
----
N
----
R
N
V
K
-----
V
F
S
L
D
T
G
R
L
H
P
E
T
Y
R
F
I
D
Q
V
R
E
H
Y
----
G
I
A
I
D
V
L
S
P
D
P
R
--
L
L
E
P
--
L
--
V
K
E
K
G
LF
S
F
-
Y
-
R
D
G
H
G
E
C
C
G
---
I
R
K
I
E
P
L
K
R
K
L
A
--
G
V
--
R
A
--
W
A
T
G
Q
R
R
D
Q
S
P
G
T
-
R
S
Q
V
A
V
L
E
I
D
-----------------------
G
A
F
-
S
TPEKP
L
Y
K
F
N
P
L
S
S
M
T
S
E
E
V
W
G
Y
I
R
M
L
E
L
P
Y
N
S
L
H
E
--
R
G
Y
I
S
I
G
C
E
P
C
T
R
P
V
L
-----
P
-------------
N
Q
H
E
R
E
G
R
W
W
W
E
---------------------------------------------
26
PsiBlast_CBE
82.17
32%
-104
- C3 -
2OQ2
1
MET16_YEAST
D:
[18-249]
------------------------
D
H
W
N
E
Q
L
I
-
K
L
E
T
P
Q
-----
E
I
---
I
A
W
S
----
I
V
T
F
P
H
-
L
F
Q
T
T
A
F
G
L
T
G
L
V
T
I
D
M
L
S
K
L
----
S
----
E
K
Y
Y
MPE--
L
L
F
I
D
T
L
H
H
F
P
Q
T
L
T
L
K
N
E
I
E
K
K
Y
YQP
K
N
Q
T
I
H
V
Y
K
P
D
G
C
--
E
S
E
A
DF
A
--
S
K
Y
G
D
--
F
L
-
W
-
E
K
D
D
D
K
Y
D
Y
---
L
A
K
V
E
P
A
H
R
A
Y
K
--
E
L
HI
S
A
--
V
F
T
G
R
R
K
S
Q
G
S
-
A
-
R
S
Q
L
S
I
I
E
I
D
-----------------------
E
L
N
-
G
-----
I
L
K
I
N
P
L
I
N
W
T
F
E
Q
V
K
Q
Y
I
D
A
N
N
V
P
Y
N
E
L
L
D
--
L
G
Y
R
S
I
G
D
Y
H
S
T
Q
P
V
K
-----
E
-------------
G
E
D
E
R
A
G
R
-------
E
C
G
I
H
E
------------------------------------
39
HHSearch
81.57
33%
-127
* C3 *
4BWV
1
?
A:
[34-260]
---------------------
I
D
I
K
K
C
N
E
Q
A
R
D
A
R
L
Q
H
L
E
A
Q
A
L
E
T
---
L
Q
K
T
----
V
E
N
F
-
E
K
P
A
F
P
C
A
L
I
A
G
D
V
V
I
L
D
L
L
H
R
I
----
G
AFSD
N
K
V
K
-----
I
I
F
I
D
T
F
H
L
F
P
E
T
Y
K
F
L
S
E
V
E
E
R
Y
---
G
-
F
K
A
H
V
F
H
A
A
D
V
NN
K
E
A
Y
--
D
--
A
K
F
G
S
--
D
L
-
F
-
I
T
D
I
E
E
Y
D
R
---
I
C
K
V
E
P
F
S
R
A
L
K
T
L
E
V
--
D
A
--
M
I
N
G
R
R
R
D
H
G
A
-
E
-
R
A
H
L
E
V
F
E
--------------------------
E
G
-
K
-----
M
V
K
V
Q
P
L
A
Y
W
E
F
R
D
C
W
D
Y
L
T
K
Y
S
L
P
Y
H
P
L
H
D
--
Q
G
F
P
S
I
G
D
V
Q
S
T
I
P
V
P
-----
R
EKWFE--------
Y
A
G
E
R
S
G
R
-------------------------------------------------
27
PsiBlast_CBE
81.41
32%
-92
- C3 -
2OQ2
1
MET16_YEAST
C:
[18-249]
------------------------
D
H
W
N
E
Q
L
I
-
K
L
E
T
P
Q
-----
E
I
---
I
A
W
S
----
I
V
T
F
P
H
-
L
F
Q
T
T
A
F
G
L
T
G
L
V
T
I
D
M
L
S
K
L
----
S
----
E
K
Y
Y
MPE--
L
L
F
I
D
T
L
H
H
F
P
Q
T
L
T
L
K
N
E
I
E
K
K
Y
YQP
K
N
Q
T
I
H
V
Y
K
P
D
G
C
--
E
S
E
A
DF
A
--
S
K
Y
G
D
--
F
L
-
W
-
E
K
D
D
D
K
Y
D
Y
---
L
A
K
V
E
P
A
H
R
A
Y
K
--
E
L
HI
S
A
--
V
F
T
G
R
R
K
S
Q
G
S
-
A
-
R
S
Q
L
S
I
I
E
I
D
-----------------------
E
L
N
-
G
-----
I
L
K
I
N
P
L
I
N
W
T
F
E
Q
V
K
Q
Y
I
D
A
N
N
V
P
Y
N
E
L
L
D
--
L
G
Y
R
S
I
G
D
Y
H
S
T
Q
P
V
K
-----
E
-------------
G
E
D
E
R
A
G
R
W
K
G
K
A
K
T
E
C
G
I
H
E
------------------------------------
43
HHSearch
78.52
24%
-159
- C3 -
1ZUN
3
CYSD_PSESM
A:
[26-231]
---------------------------------
T
H
L
K
Q
L
E
A
E
S
I
H
I
---
I
R
E
V
----
A
A
E
F
-
D
N
P
V
M
L
Y
S
I
G
K
D
S
A
V
M
L
H
L
A
R
K
A
----
F
FPGK
L
P
F
P
-----
V
M
H
V
D
T
R
W
K
F
Q
E
M
Y
R
F
R
D
Q
M
V
E
E
M
---
G
-
L
D
L
I
T
H
I
N
-----------------------------
S
A
K
H
T
D
---
I
M
K
T
E
G
L
K
Q
A
L
D
K
H
G
F
--
D
A
--
A
F
G
G
A
R
R
D
E
E
K
-
S
-
R
A
K
E
R
V
Y
S
F
R
D
SK
H
R
W
D
PKN
Q
R
P
E
L
W
NVYNGNV
N
K
G
-
E
-----
S
I
R
V
F
P
L
S
N
W
T
E
L
D
I
W
Q
Y
I
Y
L
E
G
I
P
I
V
P
L
Y
F
AA--------------------------------------------------------------------------------------------
42
HHSearch
77.50
29%
-126
- C3 -
2O8V
-
CYSH_ECOLI
A:
[33-243]
------------------------------------------
A
E
G
R
---
V
A
W
A
----
L
D
N
L
P
G
E
Y
V
L
S
S
S
F
G
I
Q
A
A
V
S
L
H
L
V
N
Q
I
----
R
----
P
D
I
P
-----
V
I
L
T
D
T
G
Y
L
F
P
E
T
Y
R
F
I
D
E
L
T
D
K
L
---
K
-
L
N
L
K
V
Y
R
A
T
E
S
--
A
A
W
Q
--
E
--
A
R
Y
G
K
LW
E
Q
-
G
-
V
E
G
I
E
K
Y
N
D
---
I
N
K
V
E
P
M
N
R
A
L
K
E
L
N
A
--
Q
T
--
W
F
A
G
L
R
R
E
Q
S
G
-
S
-
R
A
N
L
P
V
L
A
I
-------------------------
Q
R
-
G
-----
V
F
K
V
L
P
I
I
D
W
D
N
R
T
I
Y
Q
Y
L
Q
K
H
G
L
K
Y
H
P
L
W
D
--
E
G
Y
L
S
V
G
D
T
H
T
T
R
K
---------------------------------
L
K
R
E
C
G
L
H
E
------------------------------------
2
PsiBlast_PDB
76.67
32%
-122
- C3 -
4BWV
1
?
A:
[67-260]
--------------------------------------------------------------
E
K
P
A
F
P
C
A
L
I
A
G
D
V
V
I
L
D
L
L
H
R
I
GAFS
D
----
N
K
V
K
-----
I
I
F
I
D
T
F
H
L
F
P
E
T
Y
K
F
L
S
E
V
E
E
R
Y
----
G
F
K
A
H
V
F
H
A
A
D
V
--
N
N
K
E
--
A
Y
D
A
K
F
G
S
--
D
L
-
F
-
I
T
D
I
E
E
Y
D
R
---
I
C
K
V
E
P
F
S
R
A
L
K
--
T
L
EV
D
A
--
M
I
N
G
R
R
R
D
H
G
A
-
E
-
R
A
H
L
E
V
F
--------------------------
E
E
G
-
K
-----
M
V
K
V
Q
P
L
A
Y
W
E
F
R
D
C
W
D
Y
L
T
K
Y
S
L
P
Y
H
P
L
H
D
--
Q
G
F
P
S
I
G
D
V
Q
S
T
I
P
V
P
REKWF
E
-------------
Y
A
G
E
R
S
G
R
-------------------------------------------------
28
PsiBlast_CBE
76.36
32%
-122
- C3 -
4BWV
1
?
B:
[67-260]
--------------------------------------------------------------
E
K
P
A
F
P
C
A
L
I
A
G
D
V
V
I
L
D
L
L
H
R
I
GAFS
D
----
N
K
V
K
-----
I
I
F
I
D
T
F
H
L
F
P
E
T
Y
K
F
L
S
E
V
E
E
R
Y
----
G
F
K
A
H
V
F
H
A
A
D
V
--
N
N
K
E
--
A
YD
A
K
F
G
S
--
D
L
-
F
-
I
T
D
I
E
E
Y
D
R
---
I
C
K
V
E
P
F
S
R
A
L
K
--
T
L
EV
D
A
--
M
I
N
G
R
R
R
D
H
G
A
-
E
-
R
A
H
L
E
V
F
--------------------------
E
E
G
-
K
-----
M
V
K
V
Q
P
L
A
Y
W
E
F
R
D
C
W
D
Y
L
T
K
Y
S
L
P
Y
H
P
L
H
D
--
Q
G
F
P
S
I
G
D
V
Q
S
T
I
P
V
P
REKWF
E
-------------
Y
A
G
E
R
S
G
R
-------------------------------------------------
4
PsiBlast_PDB
76.20
27%
-137
- C3 -
1SUR
-
CYSH_ECOLI
A:
[17-212]
-----------------------------
I
L
A
-
L
A
E
T
N
A
E
L
E
K
L
D
A
E
G
R
V
A
W
A
----
L
D
N
L
P
G
E
Y
V
L
S
S
S
F
G
I
Q
A
A
V
S
L
H
L
V
N
Q
I
----
R
----
P
D
I
P
-----
V
I
L
T
D
T
G
Y
L
F
P
E
T
Y
R
F
I
D
E
L
T
D
K
L
---
K
-
L
N
L
K
V
Y
R
A
T
E
S
--
A
A
W
Q
--
E
--
A
R
Y
-
G
--
K
L
-
W
-
E
Q
G
V
E
G
I
E
K
Y
N
D
I
N
K
V
E
P
M
N
R
A
L
K
--
E
L
--
N
A
Q
T
W
F
A
G
L
R
R
E
Q
S
G
-
S
-
R
A
N
L
P
V
L
A
I
Q
-----------------------
R
G
--------
V
F
K
V
L
P
I
I
D
W
D
N
R
T
I
Y
Q
Y
L
Q
K
H
G
L
K
Y
H
P
L
W
D
--
E
G
Y
L
S
V
G
-------------------------------------------------------------------------------------
46
HHSearch
70.25
27%
-128
- C3 -
1SUR
-
CYSH_ECOLI
A:
[31-214]
-----------------------------------------
D
A
E
G
R
---
V
A
W
A
----
L
D
N
L
P
G
E
Y
V
L
S
S
S
F
G
I
Q
A
A
V
S
L
H
L
V
N
Q
I
----
R
----
P
D
I
P
-----
V
I
L
T
D
T
G
Y
L
F
P
E
T
Y
R
F
I
D
E
L
T
D
K
L
---
K
-
L
N
L
K
V
Y
R
A
T
E
S
--
A
A
W
Q
--
E
--
A
R
Y
G
K
L-
W
E
Q
G
-
V
E
G
I
E
K
Y
N
D
---
I
N
K
V
E
P
M
N
R
A
L
K
E
L
N
A
--
Q
T
--
W
F
A
G
L
R
R
E
Q
S
G
-
S
-
R
A
N
L
P
V
L
A
I
-------------------------
Q
R
-
G
-----
V
F
K
V
L
P
I
I
D
W
D
N
R
T
I
Y
Q
Y
L
Q
K
H
G
L
K
Y
H
P
L
W
D
--
E
G
Y
L
S
V
G
D
T
-----------------------------------------------------------------------------------
31
Fugue
67.45
19%
-100
- C3 -
3FWK
2
?
A:
[1-308]
GAMVMR
L
G
D
A
A
E
L
C
Y
N
L
T
S
S
Y
L
Q
I
A
A
E
S
D
S
I
I
-
A
Q
T
Q
R
A
I
N
T
T
K
S
I
---
L
I
N
E
TFPK
W
S
P
L
N
G
E
I
S
F
S
Y
N
G
G
K
D
C
Q
V
L
L
L
L
Y
L
S
C
----
L
----
W
E
Y
Y
IVK
L
P
T
V
F
I
D
H
D
D
T
F
K
T
L
E
N
F
I
E
E
T
S
L
R
Y
-------------
S
L
S
--
L
Y
E
S
--
D
--
R
D
K
C
E
--
T
------------
M
---
A
E
A
F
E
T
F
L
Q
V
F
P
--
E
T
--
K
A
--
I
V
I
G
I
R
H
T
D
P
F
-
G
-
E
H
L
K
P
I
Q
K
T
D
-----------------------
A
N
W
P
D
-----
F
Y
R
L
Q
P
L
L
H
W
N
L
A
N
I
W
S
F
L
L
Y
S
N
E
P
I
C
E
L
Y
R
--
Y
G
F
T
S
L
G
N
V
E
E
T
L
P
N
P
-----
H
LRKDKNST
P
L
K
L
N
F
E
W
E
I
E
N
R
Y
K
H
N
E
V
T
K
A
E
P
I
P
I
A
D
E
D
L
V
K
I
E
N
L
H
E
D
Y
Y
P
GWYLVDDKLERAGRIKKK
3
PsiBlast_PDB
64.80
27%
0
- C- -
2O8V
-
CYSH_ECOLI
A:
[18-227]
-----------------------------
I
L
A
-
L
A
E
T
N
A
E
L
E
K
L
D
A
E
G
R
V
A
W
A
----
L
D
N
L
P
G
E
Y
V
L
S
S
S
F
G
I
Q
A
A
V
S
L
H
L
V
N
Q
I
----
R
----
P
D
I
P
-----
V
I
L
T
D
T
G
Y
L
F
P
E
T
Y
R
F
I
D
E
L
T
D
K
L
---
K
-
L
N
L
K
V
Y
R
A
T
E
S
--
A
A
W
Q
--
E
--
A
R
Y
-
G
--
K
L
-
W
-
E
Q
G
V
E
G
I
E
K
Y
N
D
I
N
K
V
E
P
M
N
R
A
L
K
--
E
L
--
N
A
Q
T
W
F
A
G
L
R
R
E
Q
S
G
-
S
-
R
A
N
L
P
V
L
A
I
Q
-----------------------
R
G
--------
V
F
K
V
L
P
I
I
D
W
D
N
R
T
I
Y
Q
Y
L
Q
K
H
G
L
K
Y
H
P
L
W
D
--
E
G
Y
L
S
V
G
-------------------------------------------------------------------------------------