@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu14370: (2016-06-22 )
MSLLENIRMALSSVLAHKMRSILTMLGIIIGVGSVIVVVAVGQGGEQMLKQSISGPGNTVELYYMPSDEELASNPNAAAESTFTENDIKGLKGIEGIKQVVASTSESMKARYHEEETDATVNGINDGYMNVNSLKIESGRTFTDNDFLAGNRVGIISQKMAKELFDKTSPLGEVVWINGQPVEIIGVLKKVTGLLSFDLSEMYVPFNMMKSSFGTSDFSNVSLQVESADDIKSAGKEAAQLVNDNHGTEDSYQVMNMEEIAAGIGKVTAIMTTIIGSIAGISLLVGGIGVMNIMLVSVTERTREIGIRKSLGATRGQILTQFLIESVVLTLIGGLVGIGIGYGGAALVSAIAGWPSLISWQVVCGGVLFSMLIGVIFGMLPANKAAKLDPIEALRYE
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70---........80........90......--..100...-..-..110-...-.-...120.......130.......140.......150.--------......160.......170......----.180......--.190---.........-200....-.---..210-....---....220.......230.--......240.......250...---....260......---.270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
S
L
L
E
N
I
R
M
A
L
S
S
V
L
A
H
K
M
R
S
I
L
T
M
L
G
I
I
I
GVG
S
V
I
V
V
V
A
VGQ
G
G
E
Q
M
L
K
Q
SISGPG
N
T
V
E
L
Y
Y
MP
S
D
E
E
L---ASNPNAAAESTFTEN
D
I
KGLK
G
I
E
G
I
--
K
Q
V
V
A
S
T
S
-
E
S
-
M
K
A
R
Y-HEE-E-TDATVNGINDG
Y
M
N
V
N
S
L
K
IESGRTFTDNDFLAGNR
V
--------
G
I
I
S
Q
K
M
A
K
E
L
F
DKTSPLG
E
V
V
W
IN----GQ
P
V
E
I
I
G
V
L
--
K
K
-----
V
T
G
L
L
SF
D
L
-
S
E
M
Y
V
P
F
-
N
---
M
M
K
-
S
-SFGT---SDFS
N
V
S
L
Q
V
E
S
A
D
D
I
K
S
--
A
G
K
E
A
A
Q
L
V
NDNHGTE
D
S
Y
Q
V
M---
N
M
E
E
I
A
A
G
I
G
K
V
T
---
A
I
M
T
T
I
I
G
S
I
A
G
I
S
L
L
V
G
G
I
G
V
M
N
I
M
L
V
SV
T
E
R
T
R
E
IGI
R
K
SLGA
T
R
G
Q
I
L
T
Q
F
L
I
E
S
V
V
L
T
L
I
G
G
L
V
G
IGIGY
G
G
A
A
L
V
S
A
IAG
W
P
S
L
I
S
W
Q
V
V
C
G
G
V
L
F
S
M
L
I
G
V
I
F
G
MLPANKAAKLDP
I
E
ALRYE
1
PsiBlast_PDB
79.20
66%
-70
- C5 -
5F9Q
-
?
A:
[16-214]
---------------------------------------------------------
N
T
I
E
L
F
Y
M
P
S
D
E
E
L
---
T
A
N
P
-----
A
S
F
T
E
E
D
I
N
G
L
K
G
V
D
G
V
--
K
Q
V
V
A
S
A
V
-
K
S
-
M
T
A
R
Y
-
H
E
E
-
D
-
T
D
I
T
L
N
G
I
N
S
G
Y
M
D
V
K
K
L
D
V
Q
D
G
R
T
F
T
D
N
D
F
L
S
G
K
R
A
--------
G
I
I
S
K
K
M
A
E
K
L
F
G
K
T
S
P
L
G
K
I
V
W
A
G
----
G
Q
P
V
E
V
I
G
V
L
--
K
E
------------
G
L
-
S
E
M
Y
V
P
F
-
N
---
M
L
K
-
T
-
S
F
G
T
---
N
D
Y
S
N
V
S
V
Q
T
E
S
A
D
Q
I
K
S
--
T
G
K
E
A
A
R
L
L
N
D
N
H
G
T
K
E
A
Y
Q
V
M
---
N
------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
69.33
69%
-79
- C5 -
5F9Q
-
?
A:
[41-201]
-------------------------------------------------------------------------------------
F
T
E
E
D
I
N
G
L
K
G
V
D
G
V
--
K
Q
V
V
A
S
A
V
-
K
S
-
M
T
A
R
Y
-
H
E
E
-
D
-
T
D
I
T
L
N
G
I
N
S
G
Y
M
D
V
K
K
L
D
V
Q
D
G
R
T
F
T
D
N
D
F
L
S
G
K
R
A
--------
G
I
I
S
K
K
M
A
E
K
L
F
G
K
T
S
P
L
G
K
I
V
W
A
G
----
G
Q
P
V
E
V
I
G
V
L
--
K
E
-------------
G
L
S
E
M
Y
V
P
F
-
N
---
M
L
K
-
T
-
S
F
G
T
---
N
D
Y
S
N
V
S
V
Q
T
E
S
A
D
Q
I
K
S
--
T
G
K
E
A
A
R
L
L
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
59.79
24%
-67
- C5 -
3FTJ
-
MACB_AGGAC
A:
[307-528]
----------------------------------------------
Q
K
I
L
E
N
I
R
G
I
G
T
N
-
T
M
T
I
F
N
G
N
G
F
-----
G
D
R
R
S
R
H
I
Q
N
L
K
I
S
D
A
N
T
L
S
K
Q
S
Y
I
--
Q
S
V
T
P
N
T
S
-
S
S
-
G
I
L
V
V
G
N
K
S
-
F
-
T
S
A
N
L
Y
G
I
G
E
Q
Y
F
D
V
E
G
L
K
L
K
Q
G
R
L
L
T
E
D
D
V
D
Q
S
N
Q
V
--------
V
V
L
D
E
S
A
K
K
A
I
F
A
N
E
N
P
L
G
K
T
V
I
F
N
----
K
R
P
F
R
V
I
G
V
V
--
S
D
-----
Q
S
L
--------
N
L
Y
S
P
Y
-
S
T
--
V
L
N
-
K
-
I
T
G
G
---
S
R
I
G
S
I
T
V
K
I
S
D
D
V
N
S
T
V
--
A
E
K
S
L
T
E
L
L
K
S
L
H
G
K
K
D
-
F
F
I
M
---
N
S
D
T
I
K
Q
T
I
E
N
T
T
---
G
--------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
52.71
25%
-73
- C5 -
3FTJ
-
MACB_AGGAC
A:
[339-523]
------------------------------------------------------------------------------------
N
L
K
I
S
D
A
N
T
L
S
K
Q
S
Y
I
--
Q
S
V
T
P
N
T
S
-
S
S
-
G
I
L
V
V
-
G
N
K
S
F
-
T
S
A
N
L
Y
G
I
G
E
Q
Y
F
D
V
E
G
L
K
L
K
Q
G
R
L
L
T
E
D
D
V
D
Q
S
N
Q
V
--------
V
V
L
D
E
S
A
K
K
A
I
F
A
N
E
N
P
L
G
K
T
V
I
F
N
----
K
R
P
F
R
V
I
G
V
V
--
S
D
-----
Q
--------S
L
N
L
Y
S
P
Y
-
S
---
T
V
L
N
K
-
I
T
G
G
---
S
R
I
G
S
I
T
V
K
I
S
D
D
V
N
S
T
V
--
A
E
K
S
L
T
E
L
L
K
S
L
H
G
-
K
K
D
F
F
I
M
---
N
S
D
T
I
K
Q
T
I
----------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
52.71
28%
-98
- C5 -
3FTJ
-
MACB_AGGAC
A:
[375-528]
------------------------------------------------------------------------------------------------------------------------------
T
S
A
N
L
Y
G
I
G
E
Q
Y
F
D
V
E
G
L
K
L
K
Q
G
R
L
L
T
E
D
D
V
D
Q
S
N
Q
V
--------
V
V
L
D
E
S
A
K
K
A
I
F
A
N
E
N
P
L
G
K
T
V
I
F
N
----
K
R
P
F
R
V
I
G
V
V
S
D
Q
-------------
S
L
-
N
-
L
Y
S
P
Y
-
S
T
--
V
L
N
-
K
-
I
T
G
G
---
S
R
I
G
S
I
T
V
K
I
--
S
D
D
V
N
S
T
V
A
E
K
S
L
T
E
L
L
K
S
L
H
G
K
K
D
F
F
-
I
M
---
N
S
D
T
I
K
Q
T
I
E
N
T
T
---
G
--------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
38.03
15%
-105
- C5 -
3IS6
2
?
A:
[50-204]
-----------------------------------------------------------------------------------------------
E
I
P
G
V
--
E
L
A
T
R
T
T
L
-
Y
G
T
S
K
M
I
L
-
E
D
N
-
K
T
Y
E
T
K
T
L
L
A
E
P
A
F
L
D
M
F
G
V
E
L
I
A
G
V
R
D
S
A
L
R
---
D
N
M
T
--------
C
L
I
S
E
S
L
A
R
K
M
G
G
--
D
V
L
G
K
R
L
R
P
A
ESKS
D
R
A
I
T
I
G
G
V
F
--
E
D
-----
L
P
H
N
-
S
S
-
I
Q
A
D
M
L
L
P
I
-
T
---
W
M
P
-
A
E
S
L
N
N
WIG
N
D
R
Y
I
A
Y
V
R
L
R
P
G
V
S
P
E
S
--
L
D
E
A
L
L
E
M
Q
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
33.12
17%
-131
- C6 -
1IXS
-
A:
[21-38]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
M
A
L
A
A
L
G
F
K
E
A
Q
A
R
A
V
V
---------------------------------------------------------------------------
10
HHSearch
32.56
20%
-290
* C6 *
2L66
-
?
A:
[12-36]
----------------------------------------------------------------------------------------------------------------------------------------------------------------
N
Y
Q
--------
V
T
I
P
A
K
V
R
Q
K
F
Q
---
I
K
E
G
D
L
V
K
V
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
30.64
17%
-87
* C4 *
4D53
-
Y689_BORBU
A:
[4-136]
--------------------------------------------------------------------------------------------------------------------------------------------------------------
M
G
H
K
I
--------
D
T
--
K
E
D
M
K
I
L
Y
S
E
I
A
E
L
R
K
K
L
--
N
----
L
N
H
L
E
I
D
D
T
L
--
E
K
-----
V
A
K
E
Y
A
I
K
L
-
G
E
N
R
T
I
T
-
H
---
T
L
F
-
G
-
T
T
P
M
---
Q
R
I
H
K
Y
D
Q
S
F
N
L
T
R
E
I
L
A
--
S
G
I
E
L
N
R
V
V
N
A
W
L
N
S
P
S
H
K
E
A
L
I
NT
D
T
D
K
I
G
G
Y
R
L
K
T
T
DN
I
D
I
F
V
V
L
F
G
K
R
K
----------------------------------------------------------------------------------------------------------------------
24
Fugue
29.04
16%
-86
- C4 -
2AXP
-
YORR_BACSU
A:
[2-173]
-----------------------------------------------------------------------------------------
T
L
I
I
L
E
G
P
D
C
C
F
K
S
T
V
A
A
K
L
S
-
K
E
-
L
K
Y
P
I
-
I
K
G
-
S
-
S
F
E
L
A
K
S
G
N
E
K
L
F
E
H
F
N
K
L
A
D
E
D
N
V
I
I
D
R
-
F
V
Y
S
N
L
V
YAKKFKD
Y
S
I
L
T
E
R
Q
L
R
F
I
E
D
K
I
K
A
K
A
K
V
V
Y
L
H
----
A
D
P
S
V
I
K
K
R
L
--
R
V
R
GDEY
I
E
G
K
D
I
D
S
I
-
L
E
L
Y
R
E
V
M
S
N
AG
L
H
T
-
Y
-
S
W
D
T
---
G
Q
W
S
S
D
E
I
A
K
D
I
I
F
L
V
E
L
--
E
H
H
H
H
H
H
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
28.37
11%
-93
- C5 -
2CVI
2
?
A:
[1-83]
-------------------------------
M
V
T
A
F
I
L
M
V
T
A
A
G
K
E
R
E
V
M
E
K
L
L
A
M
P
E
V
K
E
A
Y
V
V
Y
G
E
Y
D
L
I
V
K
V
E
T
D
T
L
K
D
L
D
Q
F
I
T
E
K
I
R
K
M
P
E
I
Q
M
T
--
S
T
M
I
A
I
L
E
-
H
H
-
H
H
H
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
26.44
29%
-
- C1 -
2ROD
-
APR_MOUSE
B:
[29-35]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
G
D
K
V
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
23.07
11%
-64
- C4 -
4WV4
2
A:
[3-102]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
T
P
L
V
D
F
L
--
M
Q
-----
L
E
D
Y
-
T
P
T
I
-
P
D
A
V
T
G
Y
-
Y
---
L
N
R
-
A
-
G
F
E
A
---
S
D
P
R
I
I
R
L
I
S
L
A
A
Q
K
F
I
S
--
D
I
A
N
D
A
L
Q
H
C
K
M
K
K
Y
T
L
T
M
E
D
L
---
T
P
A
L
S
E
Y
G
I
N
V
K
-------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
22.26
27%
-109
- C5 -
2M0Q
-
KCNE2_HUMAN
A:
[64-78]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
V
A
I
L
V
S
T
V
K
S
K
R
R
E
---------------------------------------------------------------------------------------------
11
HHSearch
22.14
12%
-205
- C6 -
1YFB
-
ABRB_BACSU
A:
[15-39]
----------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
R
--------
V
V
I
P
I
E
L
R
R
T
L
G
---
I
A
E
K
D
A
L
E
I
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
21.43
30%
14
- C6 -
2X27
8
?
X:
[126-194]
-------------------------------------------------------------------
D
E
D
L
---
A
S
N
R
K
A
Q
G
F
S
S
M
K
L
Q
D
S
W
G
L
A
G
E
L
G
F
--
D
Y
M
L
N
E
H
A
L
F
N
-
M
A
V
W
Y
-
M
D
I
-
D
-
T
K
A
S
I
N
G
P
S
--
A
L
G
V
N
K
T
K
V
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
21.33
30%
22
- C2 -
2N6L
-
?
A:
[123-191]
-------------------------------------------------------------------
D
E
D
L
---
A
S
N
R
K
A
Q
G
F
S
S
M
K
L
Q
D
S
W
G
L
A
G
E
L
G
F
--
D
Y
M
L
N
E
H
A
L
F
N
-
M
A
V
W
Y
-
M
D
I
-
D
-
T
K
A
S
I
N
G
P
S
--
A
L
G
V
N
K
T
K
V
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
20.05
18%
-139
- C5 -
2F9H
-
?
A:
[52-73]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
E
G
D
H
L
K
I
G
----
D
T
N
Y
T
I
T
K
V
G
--
S
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
19.95
16%
-49
* C5 *
4FXE
1
RELB_ECOLI
A:
[12-42]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
A
R
S
Y
A
A
L
E
K
M
G
V
T
P
S
E
A
L
R
L
M
L
E
Y
I
A
D
N
E
-------------------------------------------------------------------
4
PsiBlast_PDB
15.25
28%
33
- C6 -
2N6P
-
?
A:
[102-191]
-------------------------------------------
G
G
T
N
S
A
F
Q
P
Y
G
G
L
G
V
N
Y
T
T
F
F
---
D
E
D
L
---
A
S
N
R
K
A
Q
G
F
S
S
M
K
L
Q
D
S
W
G
L
A
G
E
L
G
F
--
D
Y
M
L
N
E
H
A
L
F
N
-
M
A
V
W
Y
-
M
D
I
-
D
-
T
K
A
S
I
N
G
P
S
--
A
L
G
V
N
K
T
K
V
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------