@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu16700: (2016-06-26 )
MYKKFVPFAVFLFLFFVSFEMMENPHALDYIGAMKKDTVTVTASKDPLYEELLQKAPEYEVKPQNARIDKVWKSIPGYNGLKVNIEQSYKKMKQHGKFREKDLVYSQVKPSVHLESLQPEPIYKGNPDKPMVAFLINVAWGNEYLEKMLPILQKHQVKATFFLEGNWVRNNVQLAKKIAKDGHEIGNHSYNHPDMSKLTTGRISEQLDKTNEQIEQTIGVKPKWFAPPSGSFRKAVIDIAAEKQMGTVMWTVDTIDWQKPAPSVLQTRVLSKIHNGAMILMHPTDPTAESLEALITQIKDKGYALGTVTELMDETRLLK
Atome Classification :
(20 SA)
-------------------------------------------------------.........10........20........30...-.....40........50........60.......-.70........80........90..-......100.......110.......120.......130.......140------------------------.......150......-.160........-----170..-....-..180.......190-........200.......210.......220.-.-.....--.230....---...240.......250--------------------........---.260-----------.---.-------.......---270--.---..-....-..280-.-.----.----.---...290........300........310........--------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------------------------------------------MYKKF
V
P
F
A
V
F
L
F
L
F
F
V
S
F
E
MMENPH
A
L
D
Y
I
GAM-KK
D
T
V
T
V
TASKD
P
L
Y
E
E
L
L
Q
KAPEYEVKPQN
A
R
I
-
D
K
V
W
K
SIPGYN
G
L
K
V
N
I
E
Q
S
Y
K
K
M
K
-QHGKF
R
E
KD
L
V
Y
S
QVKP
S
V
H
LESLQPEPIYKGNPDK
P
M
V
A
F
L
I
N
VAW
G
N
------------------------
E
Y
L
E
K
M
L
P
I
L
Q
KHQ
V
K
-
A
T
F
-
F
L
EGNWVR-----
N
-
N
V
Q
-
L
A
K
K
-
I
A
KD
G
H
EIGNHSYN--HP
D
M
S
K
LTT
G
R
I
S
E
Q
L
D
K
T
N
E
Q
I
E
Q
T
IGVK-P-K-WFAPP--SG
S
F
R
K
A
V
---
I
D
I
AAEKQM
G
T
V
M
W
----------------------
T
V
DTIDWQ---KP-------------
A
---
P
-------
S
V
L
Q
T
R
V
---
L
----
S
---
K
I-HN
G
A
-
M
I
L
M
H-P-T----D----P---
T
A
E
S
-
L
E
A
L
I
T
Q
I
KDK-GY
A
L
G
T
V
T
E
L
-
M
D
E
TRLLK--------
2
PsiBlast_PDB
90.08
31%
-89
- C5 -
1NY1
-
PDAA_BACSU
A:
[56-255]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
F
Y
L
G
N
T
K
E
K
T
I
Y
L
T
F
D
N
G
Y
E
N
------------------------
G
Y
T
P
K
V
L
D
V
L
K
K
H
R
V
T
-
G
T
F
-
F
V
T
G
H
F
V
K
-----
D
-
Q
P
Q
-
L
I
K
R
-
M
S
D
E
G
H
I
I
G
N
H
S
F
H
--
H
P
D
L
T
T
K
T
A
D
Q
I
Q
D
E
L
D
S
V
N
E
E
V
Y
K
I
T
G
K
Q
-
D
-
N
L
Y
L
R
P
P
--
R
G
V
F
S
E
Y
V
---
L
K
E
T
K
R
L
G
Y
Q
T
V
F
W
----------------------
S
V
A
F
V
D
W
K
INN
Q
K
-------------
G
---
K
-------
K
Y
A
Y
D
H
M
---
I
----
K
---
Q
A
-
H
P
G
A
-
I
Y
L
L
H
-
T
V
S
----
R
----
D
---
N
A
E
A
-
L
D
D
A
I
T
D
L
K
K
Q
-
G
Y
T
F
K
S
I
D
D
L
-
M
F
E
-------------
1
PsiBlast_PDB
89.30
31%
-89
- C5 -
1W17
-
PDAA_BACSU
A:
[56-258]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
F
Y
L
G
N
T
K
E
K
T
I
Y
L
T
F
D
N
G
Y
E
N
------------------------
G
Y
T
P
K
V
L
D
V
L
K
K
H
R
V
T
-
G
T
F
-
F
V
T
G
H
F
V
K
-----
D
-
Q
P
Q
-
L
I
K
R
-
M
S
D
E
G
H
I
I
G
N
H
S
F
H
--
H
P
D
L
T
T
K
T
A
D
Q
I
Q
D
E
L
D
S
V
N
E
E
V
Y
K
I
T
G
K
Q
-
D
-
N
L
Y
L
R
P
P
--
R
G
V
F
S
E
Y
V
---
L
K
E
T
K
R
L
G
Y
Q
T
V
F
W
----------------------
S
V
A
F
V
D
W
K
INN
Q
K
-------------
G
---
K
-------
K
Y
A
Y
D
H
M
---
I
----
K
---
Q
A
-
H
P
G
A
-
I
Y
L
L
H
-
T
V
S
----
R
----
D
---
N
A
E
A
-
L
D
D
A
I
T
D
L
K
K
Q
-
G
Y
T
F
K
S
I
D
D
L
-
M
F
E
K
E
M
----------
44
HHSearch
88.65
29%
-89
- C5 -
1NY1
-
PDAA_BACSU
A:
[38-258]
----------------------------------------------------------------------------------------------------------------------------------------------------
N
H
-
Q
P
P
D
A
G
K
Q
L
N
S
L
I
E
K
Y
D
A
----------
F
Y
L
G
N
T
K
E
K
T
I
Y
L
T
F
D
N
G
Y
E
N
------------------------
G
Y
T
P
K
V
L
D
V
L
K
K
H
R
V
T
-
G
T
F
-
F
V
T
G
H
F
V
K
-----
D
-
Q
P
Q
-
L
I
K
R
-
M
S
D
E
G
H
I
I
G
N
H
S
F
H
--
H
P
D
L
T
T
K
T
A
D
Q
I
Q
D
E
L
D
S
V
N
E
E
V
Y
K
I
T
G
K
Q
-
D
N
L
-
Y
L
R
P
P
--
R
G
V
F
S
E
Y
V
---
L
K
E
T
K
R
L
G
Y
Q
T
V
F
W
----------------------
S
V
A
F
V
D
W
K
---
I
N
-------------
N
QKG
K
-------
K
Y
A
Y
D
H
M
---
I
----
K
---
Q
A
-
H
P
G
A
-
I
Y
L
L
H
-
T
-
V
S---
R
----
D
---
N
A
E
A
-
L
D
D
A
I
T
D
L
K
K
Q
-
G
Y
T
F
K
S
I
D
D
L
-
M
F
E
K
E
M
----------
60
HHSearch
88.28
23%
-121
- C5 -
3RXZ
2
?
A:
[22-282]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
T
C
A
V
A
F
T
F
D
V
D
A
E
S
P
L
L
T
T
DPAFADR
M
G
T
M
S
H
Q
A
Y
G
P
L
V
G
V
P
R
L
L
G
I
L
D
E
F
N
V
P
-
G
T
F
-
F
V
P
G
Y
T
A
H
-----
R
-
H
P
E
-
P
I
R
S
-
I
A
R
A
G
H
E
I
A
H
H
G
Y
L
--
H
E
S
L
V
G
A
D
E
D
T
E
R
K
I
L
T
R
G
I
E
A
L
E
E
V
A
G
V
H
-
P
-
V
-
G
Y
R
A
P
--
M
W
E
M
N
W
H
T
---
P
K
L
L
A
E
F
G
F
L
Y
D
S
T
LMDSD
H
P
Y
E
L
AVGD
G
S
L
V
E
LPV
S
W
A
L
D
D
W
Q
---
Q
Y
C
F
V
P
DFSGTG
L
I
E
T
---
P
-------
A
K
A
I
E
L
W
R
A
E
L
N
---
A
---
M
R
D
I
G
G
A
W
V
L
T
N
H
-
P
-
F
LSGR
P
----
G
---
R
A
A
A
-
L
R
E
F
I
A
E
V
C
A
M
D
D
V
W
V
A
G
M
S
Q
I
-
A
E
H
V
R
A
----------
21
PsiBlast_CBE
86.71
32%
-102
- C5 -
4M1B
1
?
B:
[47-246]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
I
Y
K
G
D
T
S
K
K
Q
V
A
F
T
F
D
I
S
W
G
D
------------------------
K
K
A
I
P
I
L
D
T
L
K
E
R
D
I
K
N
A
T
F
-
F
L
S
A
A
W
A
E
-----
R
-
H
P
D
-
V
V
E
R
-
I
I
K
D
G
H
E
I
G
S
M
G
Y
N
--
Y
T
S
Y
T
S
L
E
T
N
E
I
R
R
D
L
L
R
A
Q
D
V
F
T
K
-
L
G
V
K
-
Q
I
K
-
L
L
R
P
P
--
S
G
D
F
N
K
A
T
---
L
K
I
A
E
S
L
G
Y
T
V
V
H
W
----------------------
S
N
N
S
N
D
W
K
---
N
P
-------------
G
---
V
-------
N
K
I
V
S
T
V
---
S
----
N
---
N
L
-
K
G
G
D
-
I
V
L
L
H
-
A
-
S
----
D
----
S
ALQ
T
N
K
A
-
L
P
L
L
L
Q
K
L
K
S
D
-
G
Y
E
Q
I
S
V
S
Q
L
-
I
S
N
T
------------
52
HHSearch
85.55
29%
-98
- C5 -
2C1I
3
PGDA_STRR6
A:
[230-420]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
D
K
K
H
Q
K
V
V
A
L
T
F
N
D
G
P
N
P
------------------------
A
T
T
P
Q
V
L
E
T
L
A
K
Y
D
I
K
-
A
T
F
-
F
V
L
G
K
N
V
S
-----
G
-
N
E
D
-
L
V
K
R
-
I
K
S
E
G
H
V
V
G
N
H
S
W
S
--
H
P
I
L
S
Q
L
S
L
D
E
A
K
K
Q
I
T
D
T
E
D
V
L
T
K
V
L
G
S
S
-
S
-
K
-
L
M
R
P
P
--
Y
G
A
I
T
D
D
I
---
R
N
---
S
L
D
L
S
F
I
M
W
----------------------
D
V
D
S
L
D
W
K
---
S
K
-------------
N
---
E
-------
A
S
I
L
T
E
I
---
Q
----
H
---
Q
V
-
A
N
G
S
-
I
V
L
M
H
-
D
-
I
H---
S
----
P
---
T
V
N
A
-
L
P
R
V
I
E
Y
L
K
N
Q
-
G
Y
T
F
V
T
I
P
E
M
-
L
N
T
R
L
-----------
63
Fugue
85.19
27%
-68
- C5 -
1NY1
-
PDAA_BACSU
A:
[24-257]
------------------------------------------------------------------------------------------------------------------------
V
P
N
E
-
P
I
N
W
G
F
K
R
S
V
N
H
Q
P
P
D
A
G
K
Q
L
N
S
L
I
-
E
K
-----------------------
Y
D
A
F
Y
L
G
N
T
K
E
K
T
I
Y
L
T
F
D
N
G
Y
E
N
------------------------
G
Y
T
P
K
V
L
D
V
L
K
K
H
R
V
T
-
G
T
F
-
F
V
T
G
H
F
V
K
-----
D
-
Q
P
Q
-
L
I
K
R
M
S
-
D
E
G
H
I
I
G
N
H
S
F
H
--
H
P
D
L
T
T
K
T
A
D
Q
I
Q
D
E
L
D
S
V
N
E
E
V
Y
K
I
T
G
K
Q
-
D
N
L
-
Y
L
R
P
P
--
R
G
V
F
S
E
Y
V
---
L
K
E
T
K
R
L
G
Y
Q
T
V
F
W
----------------------
S
V
A
F
V
D
W
K
---
I
N
-------------
N
---
Q
KG-----
K
K
Y
A
Y
D
H
M
--
I
----
K
---
Q
A
-
H
P
G
A
-
I
Y
L
L
H
T
V
-
S
----
R
----
D
---
N
A
E
A
-
L
D
D
A
I
T
D
L
K
K
Q
-
G
Y
T
F
K
S
I
D
D
L
M
F
E
K
E
------------
3
PsiBlast_PDB
84.89
32%
-97
- C5 -
4M1B
-
?
A:
[47-246]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
I
Y
K
G
D
T
S
K
K
Q
V
A
F
T
F
D
I
S
W
G
D
------------------------
K
K
A
I
P
I
L
D
T
L
K
E
R
D
I
K
N
A
T
F
-
F
L
S
A
A
W
A
E
-----
R
-
H
P
D
-
V
V
E
R
-
I
I
K
D
G
H
E
I
G
S
M
G
Y
N
--
Y
T
S
Y
T
S
L
E
T
N
E
I
R
R
D
L
L
R
A
Q
D
V
F
T
K
-
L
G
V
K
-
Q
I
K
-
L
L
R
P
P
--
S
G
D
F
N
K
A
T
---
L
K
I
A
E
S
L
G
Y
T
V
V
H
W
----------------------
S
N
N
S
N
D
W
K
---
N
P
-------------
G
---
V
-------
N
K
I
V
S
T
V
---
S
----
N
---
N
L
-
K
G
G
D
-
I
V
L
L
H
-
A
-
S
----
D
----
S
ALQ
T
N
K
A
-
L
P
L
L
L
Q
K
L
K
S
D
-
G
Y
E
Q
I
S
V
S
Q
L
-
I
S
N
T
------------
6
PsiBlast_PDB
84.46
28%
-132
- C5 -
2J13
7
?
A:
[47-242]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
Y
L
G
D
T
K
K
K
D
I
Y
L
T
F
D
N
G
Y
E
N
------------------------
G
Y
T
G
K
I
L
D
V
L
K
E
K
K
V
P
-
A
T
F
-
F
V
T
G
H
Y
I
K
-----
T
-
Q
K
D
-
L
L
L
R
-
M
K
D
E
G
H
I
I
G
N
H
S
W
S
--
H
P
D
F
T
A
V
N
D
E
K
L
R
E
E
L
T
S
V
T
E
E
I
K
K
V
T
G
Q
K
-
E
V
K
-
Y
V
R
P
P
--
R
G
V
F
S
E
R
T
---
L
A
L
T
K
E
M
G
Y
Y
N
V
F
W
----------------------
S
L
A
F
L
D
W
---------------------------------------------------
I
-
H
P
G
S
-
I
L
L
L
H
-
A
I
S
----
K
----
D
---
N
A
E
A
-
L
A
K
I
I
D
D
L
R
E
K
-
G
Y
H
F
K
S
L
D
D
L
-
V
---------------
54
HHSearch
83.33
28%
-111
- C5 -
2C71
1
?
A:
[5-194]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
L
V
A
L
T
F
D
D
G
P
D
N
------------------------
V
L
T
A
R
V
L
D
K
L
D
K
Y
N
V
K
-
A
T
F
-
M
V
V
G
Q
R
V
N
-----
D
S
T
A
A
-
I
I
R
R
-
M
V
N
S
G
H
E
I
G
N
H
S
W
S
--
Y
S
G
M
A
N
M
S
P
D
Q
I
R
K
S
I
A
D
T
N
A
V
I
Q
K
Y
A
G
T
T
-
P
-
K
-
F
F
R
P
P
--
N
L
E
T
S
P
T
L
---
F
N
N
---
V
D
L
V
-
F
V
G
----------------------
G
L
T
A
N
D
W
I
---
P
S
T------------
T
---
A
-------
E
Q
R
A
A
A
V
---
I
----
N
---
G
V
-
R
D
G
T
-
I
I
L
L
H
-
D
-
V
----
Q
PEPH
P
---
T
P
E
A
-
L
D
I
I
I
P
T
L
K
S
R
-
G
Y
E
F
V
T
L
T
E
L
-
F
T
L
K
G
V
----------
42
HHSearch
83.09
28%
-124
- C5 -
2J13
7
?
A:
[48-245]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
L
G
D
T
K
K
K
D
I
Y
L
T
F
D
N
G
Y
E
N
------------------------
G
Y
T
G
K
I
L
D
V
L
K
E
K
K
V
P
-
A
T
F
-
F
V
T
G
H
Y
I
K
-----
T
-
Q
K
D
-
L
L
L
R
-
M
K
D
E
G
H
I
I
G
N
H
S
W
S
--
H
P
D
F
T
A
V
N
D
E
K
L
R
E
E
L
T
S
V
T
E
E
I
K
K
V
T
G
Q
K
E
V
-
K
-
Y
V
R
P
P
--
R
G
V
F
S
E
R
T
---
L
A
L
T
K
E
M
G
Y
Y
N
V
F
W
----------------------
S
L
A
F
L
D
W
---------------------------------------------------
I
-
H
P
G
S
-
I
L
L
L
H
-
A
-
I
S---
K
----
D
---
N
A
E
A
-
L
A
K
I
I
D
D
L
R
E
K
-
G
Y
H
F
K
S
L
D
D
L
-
V
K
S
N
------------
43
HHSearch
81.99
31%
-91
* C5 *
4M1B
-
?
A:
[50-246]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
K
G
D
T
S
K
K
Q
V
A
F
T
F
D
I
S
W
G
D
------------------------
K
K
A
I
P
I
L
D
T
L
K
E
R
D
I
K
N
A
T
F
-
F
L
S
A
A
W
A
E
-----
R
-
H
P
D
-
V
V
E
R
-
I
I
K
D
G
H
E
I
G
S
M
G
Y
N
--
Y
T
S
Y
T
S
L
E
T
N
E
I
R
R
D
L
L
R
A
Q
D
V
F
T
K
L
G
V
K
Q
-
I
-
K
-
L
L
R
P
P
--
S
G
D
F
N
K
A
T
---
L
K
I
A
E
S
L
G
Y
T
V
V
H
W
----------------------
S
N
N
S
N
D
W
K
---
N
P
-------------
G
---
V
-------
N
K
I
V
S
T
V
---
S
----
N
---
N
L
-
K
G
G
D
-
I
V
L
L
H
-
A
-
S
----
D
SAL-
Q
---
T
N
K
A
-
L
P
L
L
L
Q
K
L
K
S
D
-
G
Y
E
Q
I
S
V
S
Q
L
-
I
S
N
T
------------
53
HHSearch
79.01
24%
-94
- C5 -
2IW0
6
?
A:
[38-243]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
T
Q
P
G
L
V
A
L
T
Y
D
D
G
P
F
T
------------------------
F
-
T
P
Q
L
L
D
I
L
K
Q
N
D
V
R
-
A
T
F
-
F
V
N
G
N
N
W
A
NIEAG
S
-
N
P
D
-
T
I
R
R
-
M
R
A
D
G
H
L
V
G
S
H
T
Y
A
--
H
P
D
L
N
T
L
S
S
A
D
R
I
S
Q
M
R
Q
L
E
E
A
T
R
R
I
D
G
F
A
-
P
-
K
-
Y
M
R
A
P
--
Y
L
S
C
D
A
G
C
---
Q
G
D
L
G
G
L
G
Y
H
I
I
D
T
----------------------
N
L
D
T
K
D
Y
E
---
N
N
-------------
K
---
P
ET
T
H
L
S
A
E
K
F
N
N
E
L
---
S
----
A
---
D
V
G
A
N
S
Y
-
I
V
L
S
H
-
D
-
V
----
H
EQ--
T
---
V
V
S
L
-
T
Q
K
L
I
D
T
L
K
S
K
-
G
Y
R
A
V
T
V
G
E
C
-
L
G
D
A
P
E
----------
4
PsiBlast_PDB
78.59
33%
-82
- C5 -
2C1I
3
PGDA_STRR6
A:
[253-420]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
V
L
E
T
L
A
K
Y
D
I
K
-
A
T
F
-
F
V
L
G
K
N
V
S
-----
G
-
N
E
D
-
L
V
K
R
-
I
K
S
E
G
H
V
V
G
N
H
S
W
S
--
H
P
I
L
S
Q
L
S
L
D
E
A
K
K
Q
I
T
D
T
E
D
V
L
T
K
V
L
G
S
S
-
S
-
K
-
L
M
R
P
P
--
Y
G
A
I
T
D
------
D
I
R
N
S
L
D
L
S
F
I
M
W
----------------------
D
V
D
S
L
D
W
K
---
S
K
-------------
N
---
E
-------
A
S
I
L
T
E
I
---
Q
----
H
---
Q
V
-
A
N
G
S
-
I
V
L
M
H
-
D
-
I
H---
S
----
P
---
T
V
N
A
-
L
P
R
V
I
E
Y
L
K
N
Q
-
G
Y
T
F
V
T
I
P
E
M
-
L
N
-
T
R
L
----------
8
PsiBlast_PDB
78.29
28%
-108
- C5 -
2C79
1
?
A:
[5-189]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
L
V
A
L
T
F
D
D
G
P
D
N
------------------------
V
L
T
A
R
V
L
D
K
L
D
K
Y
N
V
K
-
A
T
F
-
M
V
V
G
Q
R
V
N
-----
D
-
S
T
A
A
I
I
R
R
-
M
V
N
S
G
H
E
I
G
N
H
S
W
S
--
Y
S
G
M
A
N
M
S
P
D
Q
I
R
K
S
I
A
D
T
N
A
V
I
Q
K
Y
A
G
T
T
-
P
-
K
-
F
F
R
P
P
--
N
L
E
T
S
P
T
L
F
N
N
V
D
L
V
F
V
G
G
L
T
A
N
D
W
----------------------
I
P
S
T
T
A
E
Q
---
R
A
-------------
A
----------------
A
V
---
I
----
N
---
G
V
-
R
D
G
T
-
I
I
L
L
H
-
D
-
V
----
Q
PEPH
P
---
T
P
E
A
-
L
D
I
I
I
P
T
L
K
S
R
-
G
Y
E
F
V
T
L
T
E
L
-
F
---------------
57
HHSearch
77.36
21%
-121
- C5 -
2VYO
10
YB51_ENCCU
A:
[19-220]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
D
V
C
T
N
S
G
M
I
A
I
N
F
V
D
G
P
V
R
------------------------
G
V
T
D
R
I
L
N
T
L
D
E
L
G
V
K
-
A
T
F
S
F
T
V
N
Q
K
A
V
-----
G
N
V
G
Q
-
L
Y
R
R
-
A
V
E
E
G
H
N
V
A
L
R
V
D
P
SM
D
E
G
Y
Q
C
L
S
Q
D
A
L
E
N
N
V
D
R
E
I
D
T
I
D
G
L
S
G
T
E
-
I
-
R
-
Y
A
A
V
P
IC
N
G
Q
V
N
S
E
M
---
Y
N
I
L
T
E
R
G
V
L
P
V
G
Y
----------------------
T
F
C
P
Y
D
Y
D
---
D
P
-------------
V
---
G
---------
E
F
E
S
M
---
I
----
E
G
SD
P
K
-
H
H
S
F
-
I
I
L
M
H
-
D
-
G
Q---
E
----
A
---
D
T
S
R
-
L
E
N
M
V
K
I
G
K
D
K
-
G
Y
R
F
V
N
M
D
E
C
-
L
Q
G
Y
K
-----------
7
PsiBlast_PDB
77.27
28%
-107
- C5 -
2C71
1
?
A:
[5-189]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
L
V
A
L
T
F
D
D
G
P
D
N
------------------------
V
L
T
A
R
V
L
D
K
L
D
K
Y
N
V
K
-
A
T
F
-
M
V
V
G
Q
R
V
N
-----
D
-
S
T
A
A
I
I
R
R
-
M
V
N
S
G
H
E
I
G
N
H
S
W
S
--
Y
S
G
M
A
N
M
S
P
D
Q
I
R
K
S
I
A
D
T
N
A
V
I
Q
K
Y
A
G
T
T
-
P
-
K
-
F
F
R
P
P
--
N
L
E
T
S
P
T
L
F
N
N
V
D
L
V
F
V
G
G
L
T
A
N
D
W
----------------------
I
P
S
T
T
A
E
Q
---
R
A
-------------
A
----------------
A
V
---
I
----
N
---
G
V
-
R
D
G
T
-
I
I
L
L
H
-
D
-
V
----
Q
PEPH
P
---
T
P
E
A
-
L
D
I
I
I
P
T
L
K
S
R
-
G
Y
E
F
V
T
L
T
E
L
-
F
---------------
62
Fugue
76.97
19%
-73
- C5 -
2C1I
4
PGDA_STRR6
A:
[14-431]
F
E
Q
K
I
E
S
L
K
K
E
K
D
D
Q
LSEG
N
Q
K
E
H
F
R
Q
GQ
A
E
V
I
A
Y
Y
P
L
QGEKVI
S
S
V
R
E
L
I
N
Q
D
V
K
D
K
L
E
S
K
D
N
L
V
F
Y
Y
T
E
Q
E
E
S
G
L
K
G
V
V
N
R
N
V
T
K
Q
I
Y
D
I
E
E
T
E
K
T
S
L
G
K
V
H
L
T
E
D
G
Q
P
F
T
L
D
Q
L
F
S
D
A
S
K
A
K
E
Q
L
I
K
E
L
T
S
F
D
L
S
A
W
N
F
D
Y
K
D
S
Q
I
I
L
Y
E
I
A
L
P
V
S
A
F
F
D
V
I
Q
S
S
Y
L
L
E
K
D
A
A
L
Y
Q
S
Y
F
D
K
K
H
Q
K
V
V
A
L
T
F
N
D
G
P
N
P
------------------------
A
T
T
P
Q
V
L
E
T
L
A
K
Y
D
I
K
-
A
T
F
-
F
V
L
G
K
N
V
S
-----
G
-
N
E
D
-
L
V
K
R
-
I
K
S
E
G
H
V
V
G
N
H
S
W
S
--
H
P
I
L
S
Q
L
S
L
D
E
A
K
K
Q
I
T
D
T
E
D
V
L
T
K
V
L
G
S
S
-
S
-
K
-
L
M
R
P
P
--
Y
G
A
I
T
D
D
I
---
R
N
---
S
L
D
L
S
F
I
M
W
----------------------
D
V
D
S
L
D
W
K
---
S
K
-------------
N
---
E
-------
A
S
I
L
T
E
I
---
Q
----
H
---
Q
V
-
A
N
G
S
-
I
V
L
M
H
D
I
-
H
----
S
----
P
---
T
V
N
A
-
L
P
R
V
I
E
Y
L
K
N
Q
-
G
Y
T
F
V
T
I
P
E
M
-
L
N
T
R
L
K
A
H
ELYYSRDE
5
PsiBlast_PDB
76.71
33%
-85
- C5 -
2C1G
4
PGDA_STRR6
A:
[253-420]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
V
L
E
T
L
A
K
Y
D
I
K
-
A
T
F
-
F
V
L
G
K
N
V
S
-----
G
-
N
E
D
-
L
V
K
R
-
I
K
S
E
G
H
V
V
G
N
H
S
W
S
--
H
P
I
L
S
Q
L
S
L
D
E
A
K
K
Q
I
T
D
T
E
D
V
L
T
K
V
L
G
S
S
-
S
-
K
-
L
M
R
P
P
--
Y
G
A
I
T
D
------
D
I
R
N
S
L
D
L
S
F
I
M
W
----------------------
D
V
D
S
L
D
W
K
---
S
K
-------------
N
---
E
-------
A
S
I
L
T
E
I
---
Q
----
H
---
Q
V
-
A
N
G
S
-
I
V
L
M
H
-
D
-
I
H---
S
----
P
---
T
V
N
A
-
L
P
R
V
I
E
Y
L
K
N
Q
-
G
Y
T
F
V
T
I
P
E
M
-
L
N
-
T
R
L
----------
50
HHSearch
74.36
21%
-99
- C5 -
2Y8U
6
?
A:
[27-225]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
Q
C
T
T
P
N
T
I
A
L
T
F
D
D
G
P
S
E
------------------------
Y
-
T
P
Q
L
L
D
L
L
S
R
Y
S
A
R
-
A
T
F
-
F
V
L
G
D
A
A
A
-----
Q
-
N
P
G
-
L
L
Q
R
-
M
R
D
E
G
H
Q
V
G
A
H
T
Y
D
--
H
V
S
L
P
S
L
G
Y
D
G
I
A
S
Q
M
T
R
L
E
E
V
I
R
P
A
L
G
V
A
-
P
-
A
-
Y
M
R
P
P
--
Y
L
E
T
N
E
L
V
---
L
Q
V
M
R
D
L
D
Y
R
V
I
S
A
----------------------
S
V
D
T
K
D
Y
E
---
N
Q
-------------
D
---
A
-------
D
A
I
I
N
T
S
---
F
Q
L
F
L
D
---
Q
L
D
A
G
G
N
-
I
V
L
A
H
-
D
-
I
H---
Y
----
W
---
T
V
A
S
L
A
E
R
M
L
Q
E
V
N
A
R
-
G
L
I
A
T
T
V
G
D
C
-
L
G
D
G
E
-----------