@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu17430: (2016-06-28 )
MNEQETIQEKAILVGCQLPHITDEHFENSMEELASLTKTADGKVLTSVTQKRNRADAATYIGKGKVEELKALVEELEADLLIFNDELSPSQLKSLATAIEVKMIDRTQLILDIFAKRARTREGKLQIELAQLQYALPRLTGQGINLSRQGGGIGARGPGETKLETDRRHIRNRIHEINTQLSTVIRHRSRYRERRKKNGVLQIALVGYTNAGKSTWFNRLTSADSYEEDLLFATLDPMTRKMVLPSGYSVLLSDTVGFIQDLPTTLIAAFRSTLEEVKEADLILHLIDSSNEDYAGHEKTVLRLLEELEADDIPMLTAYNKRDQKLPDFIPTAGRDHIMVSAKFEDDAAAFKEAIQRYLRQELLTSFEAHVPASEGKLLSRIKSETMVDRFYFNEENEQYDISGYVQEEQSIIGELKKYM
Atome Classification :
(20 SA)
---.......-----------..10........20......--------..30........40........50...---.....60........70........--80........90..------.....--.-100.-.......110.......120.......130.......140.-...----...150---........160.......170.......180.......190.......200.......210.......220.-.-.-....230.......240...-....250.......260...-.-...--270-........280.......290-...--....--.300....-...-----310.-----......320.-------......330------------.-------.--.-----.-.------...340.......350.......-------------360---------------........370.......380......-----.390.......400.......410.......420---------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---M
N
E
Q
E
T
I
-----------
Q
E
K
A
I
L
V
GCQLPHI
T
D
E
H
F
E
--------
N
S
M
E
E
L
A
S
L
T
KTADG
K
V
L
T
S
V
T
Q
KRNR---AD
A
A
T
YIGKG
K
V
E
E
L
K
A
L
V
E
E
LEA
D
--
L
L
I
FNDEL
S
P
S
Q
L
K
------
S
L
A
T
A
--
I
-
E
-
V
K
-
M
I
D
R
T
Q
L
I
L
D
I
F
A
K
R
ARTREG
K
L
Q
I
E
L
A
Q
L
Q
Y
A
L
P
RLTGQG-I
N
L
----SRQGG----GIGARGPGETKL
E
T
D
R
R
H
I
R
N
R
I
H
E
I
N
T
Q
L
S
T
V
I
R
H
R
S
R
Y
R
E
R
R
KKNG
V
L
Q
I
A
L
V
G
YTNAG
K
S
T
W
F
N
RLTSA-D-S-YEED
L
L
F
ATLDP
M
T
R
K
M
VLP-SG
Y
S
V
L
L
S
D
T
V
G
F
I
Q
DL
P
T
T
-
L
-
I
A
A
--
F
-
R
-
S
T
L
E
E
V
K
EA
D
L
I
L
H
L
IDSSN--EDY--AG
H
E
--
K
T
V
L
R
L
L
E
-
E
LE-----ADDI-----
P
M
L
TAYNKRD-------QKLPDFIP-------------T-------A--G-----R-
D
------
H
I
M
V
S
A
KFE
D
D
A
A
A
F
K
E
A
I
Q
R
Y
L
-------------
R
Q
----------------
E
L
L
T
S
F
E
AHVPASE
G
K
L
L
S
R
I
K
S
E
T
M
V
-----
D
R
F
Y
FNEENEQYDISG
Y
V
Q
E
E
Q
S
I
I
G
E
L
K
KYM-----------------------
39
HHSearch
87.47
28%
-119
- C4 -
2QTF
8
HFLX_SULSO
A:
[9-352]
---------------------------------------
S
K
--------
E
F
E
E
E
A
I
A
L
V
E
G
A
N
Y
K
V
T
S
I
Y
K
L
P
-
K
S
---
P
N
V
K
F
Y
I
Q
Y
D
K
L
Q
Q
I
K
N
D
---
E
E
I
S
--
T
L
I
I
F
E
Q
L
K
P
R
H
F
I
------
N
I
R
R
E
--
L
K
G
-
K
E
-
V
L
D
K
I
L
L
L
L
E
I
F
A
L
H
A
G
S
K
E
A
K
M
Q
I
E
L
A
R
L
K
Y
E
L
P
I
I
K
E
T
-------------------------------
S
T
I
K
F
Y
K
R
R
I
N
K
L
M
K
E
L
E
S
I
K
I
-------------
I
P
S
I
G
I
V
G
Y
T
N
S
G
K
T
S
L
F
N
S
L
T
G
L
--------------
M
S
P
K
R
Y
A
I
P
I
N
--
N
R
K
I
M
L
V
D
T
V
G
F
I
R
G
I
P
P
Q
-
I
-
V
D
A
--
F
-
F
-
V
T
L
S
E
A
K
Y
S
D
A
L
I
L
V
I
D
S
T
F
--
S
E
N
L
L
I
E
T
L
--
Q
S
S
F
E
I
L
R
-
E
I
G
-----
V
S
G
K
-----
P
I
L
V
T
L
N
K
I
D
-------
K
I
N
G
D
L
Y
K
K
L
D
L
V
E
K
L
S
K
---
E
-------
L
YS
P
-----
I
F
D
------
V
I
P
I
S
A
L
K
R
T
N
L
E
L
L
R
D
K
I
Y
Q
L
A
----------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
79.33
30%
0
- C- -
3KXK
-
HFLX_SULSO
A:
[14-305]
----------------------------------------------------
E
E
A
I
A
L
V
E
G
A
N
Y
K
V
-
T
S
I
Y
K
L
P
K
S
---
P
N
V
K
F
Y
I
Q
Y
D
K
L
Q
Q
I
K
---
N
D
E
E
I
S
--
T
L
I
I
F
E
Q
L
K
P
R
H
F
I
------
N
I
R
R
E
--
L
-
K
--
K
E
V
L
D
K
I
L
L
L
L
E
I
F
A
L
H
A
G
S
K
E
A
K
M
Q
I
E
L
A
R
L
K
Y
E
L
P
-
I
I
K
E
T
---------------------------------------------------------------
N
N
I
P
S
I
G
I
V
G
Y
T
N
S
G
K
T
S
L
F
N
S
L
T
G
L
---------------
S
P
--
K
R
Y
A
I
P
I
N
N
R
K
I
M
L
V
D
T
V
P
F
I
R
G
I
P
P
Q
-
I
-
V
D
A
--
F
-
F
-
V
T
L
S
E
A
K
Y
S
D
A
L
I
L
V
I
D
S
T
F
--
S
E
N
--
L
L
I
E
T
L
Q
S
S
F
E
I
L
R
-
E
I
G
-----
V
S
G
K
-----
P
I
L
V
T
L
N
K
I
D
-------
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
62
Fugue
78.53
25%
-106
- C4 -
2QTH
9
HFLX_SULSO
A:
[1-355]
-------------------------------
M
K
T
A
A
L
F
V
S
K
--------
E
F
E
E
E
A
I
A
L
V
E
G
A
-
N
Y
K
V
T
S
I
Y
K
L
P
K
S
---
P
N
V
K
F
Y
I
Q
Y
D
K
L
Q
Q
I
K
---
N
D
E
E
I
S
--
T
L
I
I
F
E
Q
L
K
P
R
H
F
I
------
N
I
R
R
E
--
L
-
K
G
K
E
-
V
L
D
K
I
L
L
L
L
E
I
F
A
L
H
A
G
S
K
E
A
K
M
Q
I
E
L
A
R
L
K
Y
E
L
P
I
I
K
E
-------------------------------
T
S
T
I
K
F
Y
K
R
R
I
N
K
L
M
K
E
L
E
S
I
K
I
I
P
-------------
S
I
G
I
V
G
Y
T
N
S
G
K
T
S
L
F
N
S
L
T
--------------
G
L
M
S
P
K
R
Y
A
I
P
I
N
--
N
R
K
I
M
L
V
D
T
V
G
F
I
R
G
I
P
P
Q
-
I
-
V
D
A
--
F
-
F
-
V
T
L
S
E
A
K
Y
S
D
A
L
I
L
V
I
D
S
T
F
S
E
N
L
L
--
I
E
T
L
--
Q
S
S
F
E
I
L
R
-
E
I
G
-----
V
S
G
K
-----
P
I
L
V
T
L
N
K
I
D
-------
K
----
I
N
G
-------------
D
-------
L
--
Y
-----
K
-
K
------
L
D
L
V
E
K
L
S
K
E
L
Y
S
P
I
F
D
V
I
P
-------------------------------------------
I
S
A
L
K
R
T
-------------------------------
N
L
E
L
L
R
D
K
I
Y
Q
L
A
T
Q
L
------------------------
3
PsiBlast_PDB
78.24
30%
-126
- C4 -
3KXI
3
HFLX_SULSO
A:
[14-304]
----------------------------------------------------
E
E
A
I
A
L
V
E
G
A
N
Y
K
V
-
T
S
I
Y
K
L
P
K
S
---
P
N
V
K
F
Y
I
Q
Y
D
K
L
Q
Q
I
K
---
N
D
E
E
I
S
--
T
L
I
I
F
E
Q
L
K
P
R
H
F
I
------
N
I
R
R
E
--
L
-
K
-
G
K
E
V
L
D
K
I
L
L
L
L
E
I
F
A
L
H
A
G
S
K
E
A
K
M
Q
I
E
L
A
R
L
K
Y
E
L
P
-
I
I
K
E
T
----------------------------
V
E
S
T
I
K
F
Y
K
R
R
I
N
K
L
M
K
E
L
E
S
I
K
I
F
K
E
K
S
I
E
S
N
K
R
N
N
I
P
S
I
G
I
V
G
Y
T
N
S
G
K
T
S
L
F
N
S
L
T
G
L
-
T
--------------
P
--
K
R
Y
A
I
P
I
N
N
R
K
I
M
L
V
D
T
V
G
F
I
R
G
I
P
P
Q
-
I
-
V
D
A
--
F
-
F
-
V
T
L
S
E
A
K
Y
S
D
A
L
I
L
V
I
D
S
T
F
--
S
E
N
--
L
L
I
E
T
L
Q
S
S
F
E
I
L
R
-
E
I
G
-----
V
S
G
K
-----
P
I
L
V
T
L
N
K
I
D
-------
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
76.52
30%
-120
- C4 -
2QTH
8
HFLX_SULSO
A:
[14-304]
----------------------------------------------------
E
E
A
I
A
L
V
E
G
A
N
Y
K
V
-
T
S
I
Y
K
L
P
K
S
---
P
N
V
K
F
Y
I
Q
Y
D
K
L
Q
Q
I
K
---
N
D
E
E
I
S
--
T
L
I
I
F
E
Q
L
K
P
R
H
F
I
------
N
I
R
R
E
--
L
-
K
-
G
K
E
V
L
D
K
I
L
L
L
L
E
I
F
A
L
H
A
G
S
K
E
A
K
M
Q
I
E
L
A
R
L
K
Y
E
L
P
-
I
I
K
E
T
------------------------------
S
T
I
K
F
Y
K
R
R
I
N
K
L
M
K
E
L
E
S
I
K
I
-------------
I
P
S
I
G
I
V
G
Y
T
N
S
G
K
T
S
L
F
N
S
L
T
G
L
--------------
M
S
P
--
K
R
Y
A
I
P
I
N
N
R
K
I
M
L
V
D
T
V
G
F
I
R
G
I
P
P
Q
-
I
-
V
D
A
--
F
-
F
-
V
T
L
S
E
A
K
Y
S
D
A
L
I
L
V
I
D
S
T
F
--
S
E
N
--
L
L
I
E
T
L
Q
S
S
F
E
I
L
R
-
E
I
G
-----
V
S
G
K
-----
P
I
L
V
T
L
N
K
I
D
-------
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
75.81
30%
-121
- C4 -
2QTF
8
HFLX_SULSO
A:
[14-304]
----------------------------------------------------
E
E
A
I
A
L
V
E
G
A
N
Y
K
V
-
T
S
I
Y
K
L
P
K
S
---
P
N
V
K
F
Y
I
Q
Y
D
K
L
Q
Q
I
K
---
N
D
E
E
I
S
--
T
L
I
I
F
E
Q
L
K
P
R
H
F
I
------
N
I
R
R
E
--
L
-
K
-
G
K
E
V
L
D
K
I
L
L
L
L
E
I
F
A
L
H
A
G
S
K
E
A
K
M
Q
I
E
L
A
R
L
K
Y
E
L
P
-
I
I
K
E
T
------------------------------
S
T
I
K
F
Y
K
R
R
I
N
K
L
M
K
E
L
E
S
I
K
I
-------------
I
P
S
I
G
I
V
G
Y
T
N
S
G
K
T
S
L
F
N
S
L
T
G
L
--------------
M
S
P
--
K
R
Y
A
I
P
I
N
N
R
K
I
M
L
V
D
T
V
G
F
I
R
G
I
P
P
Q
-
I
-
V
D
A
--
F
-
F
-
V
T
L
S
E
A
K
Y
S
D
A
L
I
L
V
I
D
S
T
F
--
S
E
N
--
L
L
I
E
T
L
Q
S
S
F
E
I
L
R
-
E
I
G
-----
V
S
G
K
-----
P
I
L
V
T
L
N
K
I
D
-------
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
69.76
30%
-115
- C4 -
3KXL
1
HFLX_SULSO
A:
[14-304]
----------------------------------------------------
E
E
A
I
A
L
V
E
G
A
N
Y
K
V
-
T
S
I
Y
K
L
P
K
S
---
P
N
V
K
F
Y
I
Q
Y
D
K
L
Q
Q
I
K
---
N
D
E
E
I
S
--
T
L
I
I
F
E
Q
L
K
P
R
H
F
I
------
N
I
R
R
E
--
L
-
K
-
G
K
E
V
L
D
K
I
L
L
L
L
E
I
F
A
L
H
A
G
S
K
E
A
K
M
Q
I
E
L
A
R
L
K
Y
E
L
P
-
I
I
K
E
T
---------------------------------------------------------------
N
N
I
P
S
I
G
I
V
G
Y
T
N
S
G
K
T
S
L
F
N
S
L
T
G
L
---------------
S
P
--
K
R
Y
A
I
P
I
N
N
R
K
I
M
L
V
D
T
V
S
F
I
R
G
I
P
P
Q
-
I
-
V
D
A
--
F
-
F
-
V
T
L
S
E
A
K
Y
S
D
A
L
I
L
V
I
D
S
T
F
--
S
E
N
--
L
L
I
E
T
L
Q
S
S
F
E
I
L
R
-
E
I
G
-----
V
S
G
K
-----
P
I
L
V
T
L
N
K
I
D
-------
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
66
Fugue
55.43
16%
-86
- C4 -
1XZP
3
MNME_THEMA
A:
[27-482]
SSV
D
K
L
M
D
T
I
V
A
VATPPGKGA
I
A
I
L
R
L
S
G
P
D
S
W
K
I
V
Q
K
H
L
R
T
R
SKIVPR
K
A
I
H
G
W
I
H
E
N
G
E
D
V
D
E
V
V
V
V
F
Y
K
S
P
K
S
YTG
E
D
M
V
E
V
M
C
H
G
G
P
L
V
V
K
K
L
L
D
L
F
L
K
S
GA
R
M
A
E
P
G
E
F
T
K
R
A
F
L
N
GKMD
L
T
S
A
E
A
--
V
-
R
-
D
L
-
I
E
A
K
S
E
T
S
L
K
L
S
L
R
N
L
K
---
G
G
L
R
D
F
V
D
S
L
R
R
E
L
I
E
V
L
A
E
I
-
R
V
E
----
L
D
Y
--------------
P
D
E
I
E
T
N
T
G
E
V
V
T
R
L
E
R
I
K
E
K
L
T
E
E
L
K
K
A
D
A
G
I
L
L
N
R
G
---
L
R
M
V
I
V
G
K
P
N
V
G
K
S
T
L
L
N
R
L
L
N
E
-
D
-
R
-
A
I
V
T
D
I
P
G
T
T
R
D
V
I
S
E
E
I
V
I
-
R
G
I
L
F
R
I
V
D
T
A
G
V
R
S
E
T
N
D
L
-
V
E
R
L
G
--
I
-
E
-
R
T
L
Q
E
I
E
K
A
D
I
V
L
F
V
L
D
A
S
S
--
P
------
L
D
--
E
E
D
R
K
I
L
E
-
R
I
K
-------
N
K
-----
R
Y
L
V
V
I
N
K
V
D
-------
V
V
E
K
I
N
E
E
-------------
E
-------
I
--
K
-----
N
-
K
L
GTDRH
M
V
K
I
S
A
L
K
G
E
G
L
E
K
L
E
E
S
I
Y
R
E
T
-------------
Q
E
I
F
E
R
G
S
DSLITN
L
R
Q
K
Q
L
L
E
N
V
K
G
H
L
E
D
A
I
K
S
L
K
E
G
M
P
V
D
M
A
S
-----
I
D
L
E
-
R
A
L
N
L
L
D
E
V
T
G
R
S
F
R
E
D
L
L
D
T
I
F
S
N
F
C
VGK--------------------
6
PsiBlast_PDB
55.34
25%
-115
- C4 -
1UDX
3
OBG_THET8
A:
[157-381]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
A
D
V
G
L
V
G
Y
P
N
A
G
K
S
S
L
L
A
A
M
T
R
A
-
H
-
P
-
K
I
A
P
Y
P
F
T
T
L
S
P
N
L
G
V
V
E
V
S
-
E
E
E
R
F
T
L
A
D
I
P
G
I
I
E
G
A
S
E
G
-
K
-
G
L
G
--
L
---
E
F
L
R
H
I
A
R
T
R
V
L
L
Y
V
L
D
A
A
D
--
E
P
L
--------
K
T
L
E
T
L
R
K
-
E
V
G
-----
A
Y
D
P
A
L
L
R
R
P
S
L
V
A
L
N
K
V
D
LLE
E
E
A
V
K
A
L
A
D
A
L
A
-------------
R
-------
E
--
G
-----
L
-
A
------
V
L
P
V
S
A
L
T
G
A
G
L
P
A
L
K
E
A
L
H
A
L
V
R
S
T
PPPEMPKPVP--------------------
Q
A
G
V
E
V
-
V
P
V
A
E
G
V
Y
E
V
R
A
P
E
---
V
-----
E
R
Y
L
A
R
I
K
G
D
L
M
E
A
A
G
Y
L
Q
E
-----------------------------------
52
HHSearch
52.99
26%
-135
- C4 -
1MKY
3
DER_THEMA
A:
[2-181]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
T
V
L
I
V
G
R
P
N
V
G
K
S
T
L
F
N
K
L
V
K
----------------
D
P
V
Q
D
T
V
E
W
Y
--
G
K
T
F
K
L
V
D
T
C
G
V
F
D
N
P
Q
D
I
-
I
-
S
Q
K
--
M
-
K
E
V
T
L
N
M
I
R
E
A
D
L
V
L
F
V
V
D
G
K
R
--
G
I
T
--
K
E
D
E
---
S
L
A
D
F
L
R
-
K
--------
S
T
V
-----
D
T
I
L
V
A
N
K
A
E
-------
N
L
R
E
F
E
R
E
V
K
P
E
L
Y
-------
S
-------
L
--
G
-----
F
G
E
------
P
I
P
V
S
A
E
H
N
I
N
L
D
T
M
L
E
T
I
I
K
K
L
----------------------------------------------------------------------------------------------------------------------
54
HHSearch
52.58
22%
-128
- C4 -
5DN8
1
DER_COXBU
A:
[177-348]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
G
I
K
I
A
M
I
G
R
P
N
V
G
K
S
T
L
I
N
R
L
L
G
E
E
R
-
V
-
I
V
Y
D
-------
S
I
Y
I
P
F
A
R
N
--
D
E
N
Y
T
L
I
D
T
A
G
I
R
R
R
A
K
I
Q
-----
K
FS
M
-
I
-
K
S
L
Q
A
M
H
A
A
D
V
V
I
F
L
L
D
A
R
Q
--
G
V
T
--
E
Q
D
L
--
R
L
L
N
R
I
V
--
E
--------
A
G
V
-----
S
L
I
I
A
V
N
K
W
D
-------
G
L
N
I
E
E
R
D
N
V
R
N
A
I
D
R
RMP--
F
-------
V
--
D
-----
F
A
R
------
R
Y
F
I
S
A
L
H
G
T
G
V
G
K
L
F
R
A
I
Q
E
S
Y
----------------------------------------------------------------------------------------------------------------------
42
HHSearch
49.79
23%
-81
- C4 -
1XZP
3
MNME_THEMA
A:
[143-403]
----------------------------------------------------------------------------------------------------------
R
A
F
L
N
G
K
M
D
L
T
S
A
E
------
A
V
R
D
L
--
I
--------------------
E
A
K
S
E
T
S
-
L
K
L
S
L
R
N
L
K
G
G
L
R
D
F
V
D
S
L
R
R
E
L
----
I
E
V
L
A
E
I
R
V
E
L
D
Y
--
P
D
E
--
I
E
T
N
T
G
E
V
V
T
R
L
E
R
I
K
E
K
L
T
E
E
L
K
K
A
D
---
A
G
I
L
L
N
R
G
L
R
M
V
I
V
G
K
P
N
V
G
K
S
T
L
L
N
R
L
L
N
E
-
D
R
A
-
I
V
T
D
I
P
G
T
T
R
D
V
I
S
E
E
I
V
I
R
--
G
I
L
F
R
I
V
D
T
A
G
V
R
S
E
T
-
N
D
-
L
-
V
E
R
LG
I
-
E
-
R
T
L
Q
E
I
E
K
A
D
I
V
L
F
V
L
D
A
S
S
--
P
L
D
--
E
E
D
R
------
K
I
L
E
-
R
I
K
-------
N
K
-----
R
Y
L
V
V
I
N
K
V
D
-------
V
V
E
K
I
N
E
E
E
I
K
N
---------
K
-------
L
--
G
T----
D
R
H
------
M
V
K
I
S
A
L
K
G
E
G
L
E
K
L
E
E
S
I
Y
R
E
T
----------------------------------------------------------------------------------------------------------------------
44
HHSearch
49.28
17%
-132
- C4 -
4B43
9
IF2_THET8
A:
[31-234]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
K
S
H
A
S
T
L
E
E
K
D
A
E
A
V
R
E
L
V
K
E
Q
R
G
L
Q
E
K
L
A
E
E
E
R
---
R
K
S
L
P
R
R
P
P
V
V
V
I
M
G
H
V
D
H
G
L
T
T
L
L
D
Y
L
R
K
S
-
R
-
I
-
A
E
K
E
A
G
G
I
T
Q
H
V
G
A
F
E
V
K
T
P
--
Q
G
T
V
V
F
I
D
T
P
G
A
E
A
-----------------------
K
V
A
D
I
A
V
I
V
I
A
A
D
D
--
G
I
M
--
P
Q
T
E
---
E
A
I
A
H
A
K
-
A
--------
A
G
A
-----
K
L
I
F
A
I
N
K
I
D
-------
L
P
Q
A
D
P
E
K
V
K
R
Q
L
M
-------
E
R
G
F
V
P
EE
Y
G-
G
-----
D
A
I
------
V
I
P
I
S
A
K
T
G
Q
G
V
Q
D
L
L
E
M
I
L
L
L
A
----------------------------------------------------------------------------------------------------------------------
63
Fugue
48.37
18%
-133
- C4 -
1EGA
3
ERA_ECOLI
A:
[4-182]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
S
Y
C
G
F
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
-
K
-
I
-
S
I
T
S
R
K
A
Q
T
T
R
H
R
I
V
G
I
H
T
E
-
G
A
Y
Q
A
I
Y
V
D
T
P
G
L
H
M
E
E
K
R
A
-
I
-
N
R
L
--
M
N
K
-
A
A
S
S
S
I
G
D
V
E
L
V
I
F
V
V
E
G
T
R
---------
W
T
--
P
D
D
E
M
V
L
N
-
K
L
R
-----
E
G
K
A
-----
P
V
I
L
A
V
N
K
V
D
NVQEK--
A
D
L
L
P
H
L
Q
-------------
F
-------
L
--
A
S
Q
MNF
L
-
D
------
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
-------------
P
E
----------------
A
T
H
H
F
P
E
--------------------------------------------------------------------------------
45
HHSearch
47.97
22%
-122
* C4 *
3IEV
2
ERA_AQUAE
A:
[10-180]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
G
Y
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
T
-
K
-
V
S
I
I
S
P
K
A
G
T
T
R
M
R
V
L
G
V
K
N
I
P
-
N
E
A
Q
I
I
F
L
D
T
P
G
I
Y
E
P
K
K
S
D
V
L
-
G
H
S
M
-
V
-
E
-
I
A
K
Q
S
L
E
E
A
D
V
I
L
F
M
I
D
A
T
E
--
G
W
R
--
P
R
D
E
--
E
I
Y
Q
N
F
I
K
-
P
--------
L
N
K
-----
P
V
I
V
V
I
N
K
I
D
-------
K
I
G
P
A
K
N
V
L
P
L
I
D
E
I
H
K
----
K
-------
H
P-
E
-----
L
T
E
------
I
V
P
I
S
A
L
K
G
A
N
L
D
E
L
V
K
T
I
L
K
Y
L
----------------------------------------------------------------------------------------------------------------------
40
HHSearch
47.79
22%
-101
- C4 -
3GEH
4
MNME_NOSS1
A:
[123-382]
----------------------------------------------------------------------------------------------------------
R
A
F
L
N
G
R
L
D
L
T
Q
A
E
------
S
I
A
D
L
--
V
--------------------
G
A
R
S
P
Q
A
-
A
Q
T
A
L
A
G
L
Q
G
K
L
A
H
P
I
R
Q
L
R
A
N
C
L
D
I
L
A
E
I
E
A
----
R
I
D
F
--
E
E
D
-
L
P
P
L
D
D
E
A
I
I
S
D
I
E
N
I
A
A
E
I
S
Q
L
L
A
T
K
D
K
G
E
---
L
L
R
T
G
L
K
V
A
I
V
G
R
P
N
V
G
K
S
S
L
L
N
A
W
S
Q
S
D
R
-
A
-
I
V
T
D
L
P
G
T
T
R
D
V
V
E
S
Q
L
V
V
G
--
G
I
P
V
Q
V
L
D
--------------------------
Q
A
A
N
T
A
D
L
V
L
L
T
I
D
A
A
T
--
G
W
T
--
T
G
D
Q
--
E
----
I
Y
E
-
Q
V
-------
K
H
R
-----
P
L
I
L
V
M
N
K
I
D
-------
L
V
E
K
Q
L
I
T
SLEY---------
P
-------
E
--
N
-----
I
T
Q
------
I
V
H
T
A
A
A
Q
K
Q
G
I
D
S
L
E
T
A
I
L
E
I
V
----------------------------------------------------------------------------------------------------------------------
56
HHSearch
47.32
22%
-111
- C4 -
1LNZ
2
OBG_BACSU
A:
[157-328]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
L
A
D
V
G
L
V
G
F
P
S
V
G
K
S
T
L
L
S
V
V
S
S
A
-
K
-
P
-
K
I
A
D
Y
H
F
T
T
L
V
P
N
L
G
M
V
E
T
D
-
D
G
R
S
F
V
M
A
D
L
P
G
L
I
E
G
A
H
Q
G
---
V
G
L
--
G
-
H
-
Q
F
L
R
H
I
E
R
T
R
V
I
V
H
V
I
D
M
S
G
--
L
E
G
--
R
D
P
Y
--
D
D
Y
L
T
I
N
Q
-
E
L
S
E
Y
NLR
L
T
E
R
-----
P
Q
I
I
V
A
N
K
M
D
-------
M
P
E
A
A
E
N
L
E
A
F
K
E
--------
K
-------
L
--
T
D----
D
Y
P
------
V
F
P
I
S
A
V
T
R
E
G
L
R
E
L
L
F
E
V
A
N
Q
L
----------------------------------------------------------------------------------------------------------------------
48
HHSearch
46.96
20%
-112
- C4 -
1WF3
4
ERA_THET8
A:
[6-172]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
S
G
F
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
V
-
K
-
V
A
P
I
S
P
R
P
Q
T
T
R
K
R
L
R
G
I
L
T
E
--
G
R
R
Q
I
V
F
V
D
T
P
G
L
H
K
P
M
D
-
A
-
L
-
G
E
F
--
M
D
Q
-
E
V
Y
E
A
L
A
D
V
N
A
V
V
W
V
V
D
L
R
H
--
P
P
T
--
P
E
D
---
E
L
V
A
R
A
L
K
-
P
L
V
------
G
K
V
-----
P
I
L
L
V
G
N
K
L
D
-------
A
A
K
Y
P
E
E
A
M
K
A
Y
H
E
-------
L
-------
L
--
P
-----
E
A
E
------
P
R
M
L
S
A
L
D
E
R
Q
V
A
E
L
K
A
D
L
L
A
L
M
-------------
P
--------------------------------------------------------------------------------------------------------
68
Fugue
46.17
19%
-43
- C4 -
1UDX
3
OBG_THET8
A:
[1-416]
---
M
F
----
Q
-----------
D
V
L
V
I
T
V
A
A
G
R
G
G
D
G
A
V
S
F
R
--------
R
E
K
F
V
P
K
G
G
P
D
G
G
D
G
G
R
G
G
S
V
Y
L
R
A
R
----------------
G
S
V
D
S
L
S
R
L
S
K
R
T
--
Y
K
A
E
D
G
E
H
G
R
G
S
Q
Q
------
H
G
R
G
G
E
D
L
-
V
-
I
E
-
V
P
R
G
T
R
V
F
D
--------
A
D
T
G
E
L
L
A
D
L
T
E
--------
E
G
Q
T
-
V
L
V
----
A
R
G
G
A
----
G
----
G
R
G
N
M
H
F
V
S
P
T
R
Q
A
P
R
F
A
E
A
G
E
E
G
E
K
R
R
L
R
L
E
L
M
L
--------
I
A
D
V
G
L
V
G
Y
P
N
A
G
K
S
S
L
L
A
A
M
T
R
A
-
H
-
P
-
K
I
A
P
Y
P
F
T
T
L
S
P
N
L
G
V
V
E
V
S
-
E
E
E
R
F
T
L
A
D
I
P
G
I
I
E
G
A
S
E
G
---
K
G
L
--
G
-
L
-
E
F
L
R
H
I
A
R
T
R
V
L
L
Y
V
L
D
A
A
D
--
E
P
L
--
K
T
L
E
--
T
L
R
K
E
V
G
A
Y
D
P
A
-----
L
L
R
R
-----
P
S
L
V
A
L
N
K
V
D
LLE
E
E
A
V
K
A
L
A
D
A
L
A
-------------
R
-------
E
--
G
-----
L
-
A
------
V
L
P
V
S
A
L
T
G
A
G
L
P
A
L
K
E
A
L
H
A
L
V
-------------
R
S
----------------
T
P
P
P
E
M
P
K
P
V
P
Q
A
G
V
E
V
V
P
V
A
E
G
V
Y
E
V
R
A
P
E
V
E
R
Y
L
A
R
I
K
G
D
L
M
E
A
A
G
Y
L
Q
E
V
F
R
R
Q
G
V
E
A
A
L
R
A
K
GVRAG
D
L
V
R
I
GG
L
E
F
E
YIPEV
46
HHSearch
46.05
18%
-117
- C4 -
1MKY
3
DER_THEMA
A:
[178-353]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
D
A
I
K
V
A
I
V
G
R
P
N
V
G
K
S
T
L
F
N
A
I
L
N
K
E
R
-
A
-
L
V
S
P
I
P
------
V
D
D
E
V
F
I
D
--
G
R
K
Y
V
F
V
D
T
A
G
L
-----------
E
K
YS
N
-
Y
-
R
V
V
D
S
I
E
K
A
D
V
V
V
I
V
L
D
A
T
Q
--
G
I
T
--
R
Q
D
Q
--
R
M
-
A
G
L
M
E
-
R
--------
R
G
R
-----
A
S
V
V
V
F
N
K
W
D
-------
L
V
V
H
R
E
K
R
Y
D
E
F
T
K
L
F
R
E
K
L
Y
F
-------
I
--
D
-----
Y
S
P
------
L
I
F
T
S
A
D
K
G
W
N
I
D
R
M
I
D
A
M
N
L
A
Y
----------------------------------------------------------------------------------------------------------------------