@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu18480: (2016-06-30 )
MRTKKRTKEMLPIFDQKKVAFIGAGSMAEGMISGIVRANKIPKQNICVTNRSNTERLTELELQYGIKGALPNQLCIEDMDVLILAMKPKDAENALSSLKSRIQPHQLILSVLAGITTSFIEQSLLNEQPVVRVMPNTSSMIGASATAIALGKYVSEDLKKLAEALLGCMGEVYTIQENQMDIFTGIAGSGPAYFYYLMEFIEKTGEEAGLDKQLSRSIGAQTLLGAAKMLMETGEHPEILRDNITSPNGTTAAGLQALKKSGGGEAISQAIKHAAKRSKEISEDIEKTAAPLSGVIK
Atome Classification :
(21 SA)
.........10..-......20........30........40........50....--....60........70--........80........90........100...-.-...110.......120....---...---130.......140.......150.......160.......170-....-...180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MRTK
K
R
T
K
E
MLPI-FDQK
K
V
A
F
I
GA
G
S
M
A
E
G
M
I
S
G
I
V
R
ANKIPKQ
N
I
C
VTNRSN
T
E
--
R
L
T
E
L
E
L
QYGIKGALP--N
Q
L
C
I
E
DM
D
V
L
I
L
A
MKPK
D
A
E
N
A
L
S
S
L
K
S
RI
Q
P
H
-
Q
-
L
I
L
S
V
L
A
G
I
T
T
S
F
I
E
Q
S
LLN---EQ
P
---
V
V
R
VMPNTSSMIGA
S
A
T
A
I
A
L
G
K
Y
V
S
E
D
L
K
K
L
A
E
A
L
L
G
CMG
E
V
-
Y
T
I
Q-ENQ
M
D
I
F
TGIAGSG
P
A
Y
F
Y
Y
L
M
E
F
I
E
KT
G
E
EAG
L
D
K
Q
L
S
R
S
I
G
A
Q
T
L
L
G
A
A
K
M
L
M
ETGE
H
P
E
I
L
R
DNITSPNG
T
T
A
A
G
L
Q
A
L
K
KSG
G
G
E
A
I
S
Q
A
I
K
H
A
A
K
R
S
K
E
I
S
E
D
I
E
K
T
AAPLSGVIK
59
PsiBlast_CBE
89.47
31%
-117
- C5 -
2IZZ
5
P5CR1_HUMAN
C:
[22-290]
----------------
S
M
S
V
G
F
I
G
A
G
Q
L
A
F
A
L
A
K
G
F
T
A
A
G
V
L
A
A
H
K
I
M
A
S
S
P
D
M
D
L
--
A
T
V
S
A
L
R
K
M
G
V
K
L
T
P
H
--
N
K
E
T
V
Q
H
S
D
V
L
F
L
A
V
K
P
H
I
I
P
F
I
L
D
E
I
G
A
D
I
E
D
R
-
H
-
I
V
V
S
C
A
A
G
V
T
I
S
S
I
E
K
K
L
S
A
---
F
R
P
APR
V
I
R
C
M
T
N
T
P
V
V
V
R
E
G
A
T
V
Y
A
T
G
T
H
A
Q
V
E
D
G
R
L
M
E
Q
L
L
S
S
V
G
F
C
-
T
E
V
E
-
E
D
L
I
D
A
V
T
G
L
S
G
S
G
P
A
Y
A
F
T
A
L
D
A
L
A
D
G
G
V
K
M
G
L
P
R
R
L
A
V
R
L
G
A
Q
A
L
L
G
A
A
K
M
L
L
H
S
E
Q
H
P
G
Q
L
K
D
N
V
S
S
P
G
G
A
T
I
H
A
L
H
V
L
E
S
G
G
F
R
S
L
L
I
N
A
V
E
A
S
C
I
R
T
R
E
L
----------------
60
PsiBlast_CBE
89.32
31%
-118
- C5 -
2IZZ
5
P5CR1_HUMAN
B:
[20-290]
--------------
F
Q
S
M
S
V
G
F
I
G
A
G
Q
L
A
F
A
L
A
K
G
F
T
A
A
G
V
L
A
A
H
K
I
M
A
S
S
P
D
M
D
L
--
A
T
V
S
A
L
R
K
M
G
V
K
L
T
P
H
--
N
K
E
T
V
Q
H
S
D
V
L
F
L
A
V
K
P
H
I
I
P
F
I
L
D
E
I
G
A
D
I
E
D
R
-
H
-
I
V
V
S
C
A
A
G
V
T
I
S
S
I
E
K
K
L
S
A
---
F
R
P
APR
V
I
R
C
M
T
N
T
P
V
V
V
R
E
G
A
T
V
Y
A
T
G
T
H
A
Q
V
E
D
G
R
L
M
E
Q
L
L
S
S
V
G
F
C
-
T
E
V
E
-
E
D
L
I
D
A
V
T
G
L
S
G
S
G
P
A
Y
A
F
T
A
L
D
A
L
A
D
G
G
V
K
M
G
L
P
R
R
L
A
V
R
L
G
A
Q
A
L
L
G
A
A
K
M
L
L
H
S
E
Q
H
P
G
Q
L
K
D
N
V
S
S
P
G
G
A
T
I
H
A
L
H
V
L
E
S
G
G
F
R
S
L
L
I
N
A
V
E
A
S
C
I
R
T
R
E
L
----------------
58
PsiBlast_CBE
89.08
31%
-117
- C5 -
2IZZ
5
P5CR1_HUMAN
D:
[20-290]
--------------
F
Q
S
M
S
V
G
F
I
G
A
G
Q
L
A
F
A
L
A
K
G
F
T
A
A
G
V
L
A
A
H
K
I
M
A
S
S
P
D
M
D
L
--
A
T
V
S
A
L
R
K
M
G
V
K
L
T
P
H
--
N
K
E
T
V
Q
H
S
D
V
L
F
L
A
V
K
P
H
I
I
P
F
I
L
D
E
I
G
A
D
I
E
D
R
-
H
-
I
V
V
S
C
A
A
G
V
T
I
S
S
I
E
K
K
L
S
A
---
F
R
P
APR
V
I
R
C
M
T
N
T
P
V
V
V
R
E
G
A
T
V
Y
A
T
G
T
H
A
Q
V
E
D
G
R
L
M
E
Q
L
L
S
S
V
G
F
C
-
T
E
V
E
-
E
D
L
I
D
A
V
T
G
L
S
G
S
G
P
A
Y
A
F
T
A
L
D
A
L
A
D
G
G
V
K
M
G
L
P
R
R
L
A
V
R
L
G
A
Q
A
L
L
G
A
A
K
M
L
L
H
S
E
Q
H
P
G
Q
L
K
D
N
V
S
S
P
G
G
A
T
I
H
A
L
H
V
L
E
S
G
G
F
R
S
L
L
I
N
A
V
E
A
S
C
I
R
T
R
E
L
----------------
57
PsiBlast_CBE
88.60
31%
-119
- C5 -
2IZZ
2
P5CR1_HUMAN
E:
[23-290]
-----------------
M
S
V
G
F
I
G
A
G
Q
L
A
F
A
L
A
K
G
F
T
A
A
G
V
L
A
A
H
K
I
M
A
S
S
P
D
M
D
L
--
A
T
V
S
A
L
R
K
M
G
V
K
L
T
P
H
--
N
K
E
T
V
Q
H
S
D
V
L
F
L
A
V
K
P
H
I
I
P
F
I
L
D
E
I
G
A
D
I
E
D
R
-
H
-
I
V
V
S
C
A
A
G
V
T
I
S
S
I
E
K
K
L
S
A
---
F
R
P
APR
V
I
R
C
M
T
N
T
P
V
V
V
R
E
G
A
T
V
Y
A
T
G
T
H
A
Q
V
E
D
G
R
L
M
E
Q
L
L
S
S
V
G
F
C
-
T
E
V
E
-
E
D
L
I
D
A
V
T
G
L
S
G
S
G
P
A
Y
A
F
T
A
L
D
A
L
A
D
G
G
V
K
M
G
L
P
R
R
L
A
V
R
L
G
A
Q
A
L
L
G
A
A
K
M
L
L
H
S
E
Q
H
P
G
Q
L
K
D
N
V
S
S
P
G
G
A
T
I
H
A
L
H
V
L
E
S
G
G
F
R
S
L
L
I
N
A
V
E
A
S
C
I
R
T
R
E
L
----------------
6
PsiBlast_PDB
87.67
31%
-112
- C5 -
2IZZ
5
P5CR1_HUMAN
A:
[22-290]
----------------
S
M
S
V
G
F
I
G
A
G
Q
L
A
F
A
L
A
K
G
F
T
A
A
G
V
L
A
A
H
K
I
M
A
S
S
P
D
M
D
L
--
A
T
V
S
A
L
R
K
M
G
V
K
L
T
P
H
--
N
K
E
T
V
Q
H
S
D
V
L
F
L
A
V
K
P
H
I
I
P
F
I
L
D
E
I
G
A
D
I
E
D
R
-
H
-
I
V
V
S
C
A
A
G
V
T
I
S
S
I
E
K
K
L
S
A
---
F
R
P
A
P
R
V
I
R
C
M
T
N
T
P
V
V
V
R
E
G
A
T
V
Y
A
T
G
T
H
A
Q
V
E
D
G
R
L
M
E
Q
L
L
S
S
V
G
F
C
-
T
E
V
E
-
E
D
L
I
D
A
V
T
G
L
S
G
S
G
P
A
Y
A
F
T
A
L
D
A
L
A
D
G
G
V
K
M
G
L
P
R
R
L
A
V
R
L
G
A
Q
A
L
L
G
A
A
K
M
L
L
H
S
E
Q
H
P
G
Q
L
K
D
N
V
S
S
P
G
G
A
T
I
H
A
L
H
V
L
E
S
G
G
F
R
S
L
L
I
N
A
V
E
A
S
C
I
R
T
R
E
L
----------------
66
PsiBlast_CBE
87.14
31%
-125
- C5 -
2GR9
1
P5CR1_HUMAN
D:
[5-270]
-------------------
V
G
F
I
G
A
G
Q
L
A
F
A
L
A
K
G
F
T
A
A
G
V
L
A
A
H
K
I
M
A
S
S
P
D
M
D
L
--
A
T
V
S
A
L
R
K
M
G
V
K
L
T
P
H
--
N
K
E
T
V
Q
H
S
D
V
L
F
L
A
V
K
P
H
I
I
P
F
I
L
D
E
I
G
A
D
I
E
D
R
-
H
-
I
V
V
S
C
A
A
G
V
T
I
S
S
I
E
K
K
L
S
A
---
F
R
P
APR
V
I
R
C
M
T
N
T
P
V
V
V
R
E
G
A
T
V
Y
A
T
G
T
H
A
Q
V
E
D
G
R
L
M
E
Q
L
L
S
S
V
G
F
C
-
T
E
V
E
-
E
D
L
I
D
A
V
T
G
L
S
G
S
G
P
A
Y
A
F
T
A
L
D
A
L
A
D
G
G
V
K
M
G
L
P
R
R
L
A
V
R
L
G
A
Q
A
L
L
G
A
A
K
M
L
L
H
S
E
Q
H
P
G
Q
L
K
D
N
V
S
S
P
G
G
A
T
I
H
A
L
H
V
L
E
S
G
G
F
R
S
L
L
I
N
A
V
E
A
S
C
I
R
T
R
E
L
----------------
7
PsiBlast_PDB
85.79
31%
-118
- C5 -
2GER
-
P5CR1_HUMAN
A:
[3-268]
-------------------
V
G
F
I
G
A
G
Q
L
A
F
A
L
A
K
G
F
T
A
A
G
V
L
A
A
H
K
I
M
A
S
S
P
D
M
D
L
--
A
T
V
S
A
L
R
K
M
G
V
K
L
T
P
H
--
N
K
E
T
V
Q
H
S
D
V
L
F
L
A
V
K
P
H
I
I
P
F
I
L
D
E
I
G
A
D
I
E
D
R
-
H
-
I
V
V
S
C
A
A
G
V
T
I
S
S
I
E
K
K
L
S
A
---
F
R
P
A
P
R
V
I
R
C
M
T
N
T
P
V
V
V
R
E
G
A
T
V
Y
A
T
G
T
H
A
Q
V
E
D
G
R
L
M
E
Q
L
L
S
S
V
G
F
C
-
T
E
V
E
-
E
D
L
I
D
A
V
T
G
L
S
G
S
G
P
A
Y
A
F
T
A
L
D
A
L
A
D
G
G
V
K
M
G
L
P
R
R
L
A
V
R
L
G
A
Q
A
L
L
G
A
A
K
M
L
L
H
S
E
Q
H
P
G
Q
L
K
D
N
V
S
S
P
G
G
A
T
I
H
A
L
H
V
L
E
S
G
G
F
R
S
L
L
I
N
A
V
E
A
S
C
I
R
T
R
E
L
----------------
87
HHSearch
85.71
34%
-47
- C5 -
3TRI
5
?
A:
[2-272]
---------------
N
T
S
N
I
T
F
I
G
G
G
N
M
A
R
N
I
V
V
G
L
I
A
N
G
Y
-
D
P
N
R
I
C
V
T
N
R
S
-
L
D
--
K
L
D
F
F
K
E
K
C
G
V
H
--
T
T
QD
N
R
Q
G
A
L
N
A
D
V
V
V
L
A
V
K
P
H
Q
I
K
M
V
C
E
E
L
K
D
I
L
S
E
T
K
I
-
L
V
I
S
L
A
V
G
V
T
T
P
L
I
E
K
W
L
G
K
---
A
S
R
---
I
V
R
A
M
P
N
T
P
S
S
V
R
A
G
A
T
G
L
F
A
N
E
T
V
D
K
D
Q
K
N
L
A
E
S
I
M
R
A
V
G
L
V
-
I
W
V
S
S
E
D
Q
I
E
K
I
A
A
L
S
G
S
G
P
A
Y
I
F
L
I
M
E
A
L
Q
E
A
A
E
Q
L
G
L
T
K
E
T
A
E
L
L
T
E
Q
T
V
L
G
A
A
R
M
A
L
E
T
E
Q
S
V
V
Q
L
R
Q
F
V
T
S
P
G
G
T
T
E
Q
A
I
K
V
L
E
S
G
N
L
R
E
L
F
I
K
A
L
T
A
A
V
N
R
A
K
E
L
S
K
T
V
------------
9
PsiBlast_PDB
85.55
31%
-117
- C5 -
2GRA
1
P5CR1_HUMAN
A:
[5-270]
-------------------
V
G
F
I
G
A
G
Q
L
A
F
A
L
A
K
G
F
T
A
A
G
V
L
A
A
H
K
I
M
A
S
S
P
D
M
D
L
--
A
T
V
S
A
L
R
K
M
G
V
K
L
T
P
H
--
N
K
E
T
V
Q
H
S
D
V
L
F
L
A
V
K
P
H
I
I
P
F
I
L
D
E
I
G
A
D
I
E
D
R
-
H
-
I
V
V
S
C
A
A
G
V
T
I
S
S
I
E
K
K
L
S
A
---
F
R
P
A
P
R
V
I
R
C
M
T
N
T
P
V
V
V
R
E
G
A
T
V
Y
A
T
G
T
H
A
Q
V
E
D
G
R
L
M
E
Q
L
L
S
S
V
G
F
C
-
T
E
V
E
-
E
D
L
I
D
A
V
T
G
L
S
G
S
G
P
A
Y
A
F
T
A
L
D
A
L
A
D
G
G
V
K
M
G
L
P
R
R
L
A
V
R
L
G
A
Q
A
L
L
G
A
A
K
M
L
L
H
S
E
Q
H
P
G
Q
L
K
D
N
V
S
S
P
G
G
A
T
I
H
A
L
H
V
L
E
S
G
G
F
R
S
L
L
I
N
A
V
E
A
S
C
I
R
T
R
E
L
----------------
5
PsiBlast_PDB
85.25
32%
-80
- C5 -
3TRI
5
?
A:
[6-273]
-------------------
I
T
F
I
G
G
G
N
M
A
R
N
I
V
V
G
L
I
-
A
N
G
Y
D
P
N
R
I
C
V
T
N
R
S
-
L
D
--
K
L
D
F
F
K
E
K
C
G
V
H
T
T
Q
D
--
N
R
Q
G
A
L
N
A
D
V
V
V
L
A
V
K
P
H
Q
I
K
M
V
C
E
E
L
K
D
I
L
S
E
T
-
K
I
L
V
I
S
L
A
V
G
V
T
T
P
L
I
E
K
W
L
G
K
---
A
S
R
---
I
V
R
A
M
P
N
T
P
S
S
V
R
A
G
A
T
G
L
F
A
N
E
T
V
D
K
D
Q
K
N
L
A
E
S
I
M
R
A
V
G
L
V
I
W
V
S
S
-
E
D
Q
I
E
K
I
A
A
L
S
G
S
G
P
A
Y
I
F
L
I
M
E
A
L
Q
E
A
A
E
Q
L
G
L
T
K
E
T
A
E
L
L
T
E
Q
T
V
L
G
A
A
R
M
A
L
E
T
E
Q
S
V
V
Q
L
R
Q
F
V
T
S
P
G
G
T
T
E
Q
A
I
K
V
L
E
S
G
N
L
R
E
L
F
I
K
A
L
T
A
A
V
N
R
A
K
E
L
S
K
T
V
D
-----------
61
PsiBlast_CBE
85.05
31%
-117
- C5 -
2GRA
1
P5CR1_HUMAN
E:
[5-270]
-------------------
V
G
F
I
G
A
G
Q
L
A
F
A
L
A
K
G
F
T
A
A
G
V
L
A
A
H
K
I
M
A
S
S
P
D
M
D
L
--
A
T
V
S
A
L
R
K
M
G
V
K
L
T
P
H
--
N
K
E
T
V
Q
H
S
D
V
L
F
L
A
V
K
P
H
I
I
P
F
I
L
D
E
I
G
A
D
I
E
D
R
-
H
-
I
V
V
S
C
A
A
G
V
T
I
S
S
I
E
K
K
L
S
A
---
F
R
P
APR
V
I
R
C
M
T
N
T
P
V
V
V
R
E
G
A
T
V
Y
A
T
G
T
H
A
Q
V
E
D
G
R
L
M
E
Q
L
L
S
S
V
G
F
C
-
T
E
V
E
-
E
D
L
I
D
A
V
T
G
L
S
G
S
G
P
A
Y
A
F
T
A
L
D
A
L
A
D
G
G
V
K
M
G
L
P
R
R
L
A
V
R
L
G
A
Q
A
L
L
G
A
A
K
M
L
L
H
S
E
Q
H
P
G
Q
L
K
D
N
V
S
S
P
G
G
A
T
I
H
A
L
H
V
L
E
S
G
G
F
R
S
L
L
I
N
A
V
E
A
S
C
I
R
T
R
E
L
----------------
8
PsiBlast_PDB
84.83
31%
-118
- C5 -
2GR9
1
P5CR1_HUMAN
A:
[5-270]
-------------------
V
G
F
I
G
A
G
Q
L
A
F
A
L
A
K
G
F
T
A
A
G
V
L
A
A
H
K
I
M
A
S
S
P
D
M
D
L
--
A
T
V
S
A
L
R
K
M
G
V
K
L
T
P
H
--
N
K
E
T
V
Q
H
S
D
V
L
F
L
A
V
K
P
H
I
I
P
F
I
L
D
E
I
G
A
D
I
E
D
R
-
H
-
I
V
V
S
C
A
A
G
V
T
I
S
S
I
E
K
K
L
S
A
---
F
R
P
A
P
R
V
I
R
C
M
T
N
T
P
V
V
V
R
E
G
A
T
V
Y
A
T
G
T
H
A
Q
V
E
D
G
R
L
M
E
Q
L
L
S
S
V
G
F
C
-
T
E
V
E
-
E
D
L
I
D
A
V
T
G
L
S
G
S
G
P
A
Y
A
F
T
A
L
D
A
L
A
D
G
G
V
K
M
G
L
P
R
R
L
A
V
R
L
G
A
Q
A
L
L
G
A
A
K
M
L
L
H
S
E
Q
H
P
G
Q
L
K
D
N
V
S
S
P
G
G
A
T
I
H
A
L
H
V
L
E
S
G
G
F
R
S
L
L
I
N
A
V
E
A
S
C
I
R
T
R
E
L
----------------
65
PsiBlast_CBE
84.69
31%
-118
- C5 -
2GR9
2
P5CR1_HUMAN
E:
[5-270]
-------------------
V
G
F
I
G
A
G
Q
L
A
F
A
L
A
K
G
F
T
A
A
G
V
L
A
A
H
K
I
M
A
S
S
P
D
M
D
L
--
A
T
V
S
A
L
R
K
M
G
V
K
L
T
P
H
--
N
K
E
T
V
Q
H
S
D
V
L
F
L
A
V
K
P
H
I
I
P
F
I
L
D
E
I
G
A
D
I
E
D
R
-
H
-
I
V
V
S
C
A
A
G
V
T
I
S
S
I
E
K
K
L
S
A
---
F
R
P
APR
V
I
R
C
M
T
N
T
P
V
V
V
R
E
G
A
T
V
Y
A
T
G
T
H
A
Q
V
E
D
G
R
L
M
E
Q
L
L
S
S
V
G
F
C
-
T
E
V
E
-
E
D
L
I
D
A
V
T
G
L
S
G
S
G
P
A
Y
A
F
T
A
L
D
A
L
A
D
G
G
V
K
M
G
L
P
R
R
L
A
V
R
L
G
A
Q
A
L
L
G
A
A
K
M
L
L
H
S
E
Q
H
P
G
Q
L
K
D
N
V
S
S
P
G
G
A
T
I
H
A
L
H
V
L
E
S
G
G
F
R
S
L
L
I
N
A
V
E
A
S
C
I
R
T
R
E
L
----------------
63
PsiBlast_CBE
84.65
31%
-117
- C5 -
2GRA
1
P5CR1_HUMAN
C:
[5-270]
-------------------
V
G
F
I
G
A
G
Q
L
A
F
A
L
A
K
G
F
T
A
A
G
V
L
A
A
H
K
I
M
A
S
S
P
D
M
D
L
--
A
T
V
S
A
L
R
K
M
G
V
K
L
T
P
H
--
N
K
E
T
V
Q
H
S
D
V
L
F
L
A
V
K
P
H
I
I
P
F
I
L
D
E
I
G
A
D
I
E
D
R
-
H
-
I
V
V
S
C
A
A
G
V
T
I
S
S
I
E
K
K
L
S
A
---
F
R
P
APR
V
I
R
C
M
T
N
T
P
V
V
V
R
E
G
A
T
V
Y
A
T
G
T
H
A
Q
V
E
D
G
R
L
M
E
Q
L
L
S
S
V
G
F
C
-
T
E
V
E
-
E
D
L
I
D
A
V
T
G
L
S
G
S
G
P
A
Y
A
F
T
A
L
D
A
L
A
D
G
G
V
K
M
G
L
P
R
R
L
A
V
R
L
G
A
Q
A
L
L
G
A
A
K
M
L
L
H
S
E
Q
H
P
G
Q
L
K
D
N
V
S
S
P
G
G
A
T
I
H
A
L
H
V
L
E
S
G
G
F
R
S
L
L
I
N
A
V
E
A
S
C
I
R
T
R
E
L
----------------
62
PsiBlast_CBE
84.57
31%
-120
- C5 -
2GRA
1
P5CR1_HUMAN
D:
[5-270]
-------------------
V
G
F
I
G
A
G
Q
L
A
F
A
L
A
K
G
F
T
A
A
G
V
L
A
A
H
K
I
M
A
S
S
P
D
M
D
L
--
A
T
V
S
A
L
R
K
M
G
V
K
L
T
P
H
--
N
K
E
T
V
Q
H
S
D
V
L
F
L
A
V
K
P
H
I
I
P
F
I
L
D
E
I
G
A
D
I
E
D
R
-
H
-
I
V
V
S
C
A
A
G
V
T
I
S
S
I
E
K
K
L
S
A
---
F
R
P
APR
V
I
R
C
M
T
N
T
P
V
V
V
R
E
G
A
T
V
Y
A
T
G
T
H
A
Q
V
E
D
G
R
L
M
E
Q
L
L
S
S
V
G
F
C
-
T
E
V
E
-
E
D
L
I
D
A
V
T
G
L
S
G
S
G
P
A
Y
A
F
T
A
L
D
A
L
A
D
G
G
V
K
M
G
L
P
R
R
L
A
V
R
L
G
A
Q
A
L
L
G
A
A
K
M
L
L
H
S
E
Q
H
P
G
Q
L
K
D
N
V
S
S
P
G
G
A
T
I
H
A
L
H
V
L
E
S
G
G
F
R
S
L
L
I
N
A
V
E
A
S
C
I
R
T
R
E
L
----------------
67
PsiBlast_CBE
83.53
31%
-116
- C5 -
2GR9
2
P5CR1_HUMAN
C:
[5-270]
-------------------
V
G
F
I
G
A
G
Q
L
A
F
A
L
A
K
G
F
T
A
A
G
V
L
A
A
H
K
I
M
A
S
S
P
D
M
D
L
--
A
T
V
S
A
L
R
K
M
G
V
K
L
T
P
H
--
N
K
E
T
V
Q
H
S
D
V
L
F
L
A
V
K
P
H
I
I
P
F
I
L
D
E
I
G
A
D
I
E
D
R
-
H
-
I
V
V
S
C
A
A
G
V
T
I
S
S
I
E
K
K
L
S
A
---
F
R
P
APR
V
I
R
C
M
T
N
T
P
V
V
V
R
E
G
A
T
V
Y
A
T
G
T
H
A
Q
V
E
D
G
R
L
M
E
Q
L
L
S
S
V
G
F
C
-
T
E
V
E
-
E
D
L
I
D
A
V
T
G
L
S
G
S
G
P
A
Y
A
F
T
A
L
D
A
L
A
D
G
G
V
K
M
G
L
P
R
R
L
A
V
R
L
G
A
Q
A
L
L
G
A
A
K
M
L
L
H
S
E
Q
H
P
G
Q
L
K
D
N
V
S
S
P
G
G
A
T
I
H
A
L
H
V
L
E
S
G
G
F
R
S
L
L
I
N
A
V
E
A
S
C
I
R
T
R
E
L
----------------
86
HHSearch
82.88
32%
-35
- C5 -
2IZZ
5
P5CR1_HUMAN
A:
[22-293]
----------------
S
M
S
V
G
F
I
G
A
G
Q
L
A
F
A
L
A
K
G
F
T
A
A
G
V
L
A
A
H
K
I
M
A
S
S
P
D
-
M
D
L
A
T
V
S
A
L
R
K
-
M
G
V
K
--
L
T
PH
N
K
E
T
V
Q
H
S
D
V
L
F
L
A
V
K
P
H
I
I
P
F
I
L
D
E
I
G
A
D
I
E
D
R
-
H
-
I
V
V
S
C
A
A
G
V
T
I
S
S
I
E
K
K
L
S
A
F
RP
A
P
R
---
V
I
R
C
M
T
N
T
P
V
V
V
R
E
G
A
T
V
Y
A
T
G
T
H
A
Q
V
E
D
G
R
L
M
E
Q
L
L
S
S
V
G
F
C
-
T
E
V
E
-
E
D
L
I
D
A
V
T
G
L
S
G
S
G
P
A
Y
A
F
T
A
L
D
A
L
A
D
G
G
V
K
M
G
L
P
R
R
L
A
V
R
L
G
A
Q
A
L
L
G
A
A
K
M
L
L
H
S
E
Q
H
P
G
Q
L
K
D
N
V
S
S
P
G
G
A
T
I
H
A
L
H
V
L
E
S
G
G
F
R
S
L
L
I
N
A
V
E
A
S
C
I
R
T
R
E
L
Q
S
M
-------------
64
PsiBlast_CBE
82.77
31%
-123
- C5 -
2GRA
2
P5CR1_HUMAN
B:
[5-270]
-------------------
V
G
F
I
G
A
G
Q
L
A
F
A
L
A
K
G
F
T
A
A
G
V
L
A
A
H
K
I
M
A
S
S
P
D
M
D
L
--
A
T
V
S
A
L
R
K
M
G
V
-
L
T
P
H
--
N
K
E
T
V
Q
H
S
D
V
L
F
L
A
V
K
P
H
I
I
P
F
I
L
D
E
I
G
A
D
I
E
D
R
-
H
-
I
V
V
S
C
A
A
G
V
T
I
S
S
I
E
K
K
L
S
A
---
F
R
P
A
P
R
V
I
R
C
M
T
N
T
P
V
V
V
R
E
G
A
T
V
Y
A
T
G
T
H
A
Q
V
E
D
G
R
L
M
E
Q
L
L
S
S
V
G
F
C
-
T
E
V
E
-
E
D
L
I
D
A
V
T
G
L
S
G
S
G
P
A
Y
A
F
T
A
L
D
A
L
A
D
G
G
V
K
M
G
L
P
R
R
L
A
V
R
L
G
A
Q
A
L
L
G
A
A
K
M
L
L
H
S
E
Q
H
P
G
Q
L
K
D
N
V
S
S
P
G
G
A
T
I
H
A
L
H
V
L
E
S
G
G
F
R
S
L
L
I
N
A
V
E
A
S
C
I
R
T
R
E
L
----------------
68
PsiBlast_CBE
82.55
31%
-126
- C5 -
2GR9
2
P5CR1_HUMAN
B:
[5-270]
-------------------
V
G
F
I
G
A
G
Q
L
A
F
A
L
A
K
G
F
T
A
A
G
V
L
A
A
H
K
I
M
A
S
S
P
D
M
D
L
--
A
T
V
S
A
L
R
K
M
G
V
-
L
T
P
H
--
N
K
E
T
V
Q
H
S
D
V
L
F
L
A
V
K
P
H
I
I
P
F
I
L
D
E
I
G
A
D
I
E
D
R
-
H
-
I
V
V
S
C
A
A
G
V
T
I
S
S
I
E
K
K
L
S
A
---
F
R
P
A
P
R
V
I
R
C
M
T
N
T
P
V
V
V
R
E
G
A
T
V
Y
A
T
G
T
H
A
Q
V
E
D
G
R
L
M
E
Q
L
L
S
S
V
G
F
C
-
T
E
V
E
-
E
D
L
I
D
A
V
T
G
L
S
G
S
G
P
A
Y
A
F
T
A
L
D
A
L
A
D
G
G
V
K
M
G
L
P
R
R
L
A
V
R
L
G
A
Q
A
L
L
G
A
A
K
M
L
L
H
S
E
Q
H
P
G
Q
L
K
D
N
V
S
S
P
G
G
A
T
I
H
A
L
H
V
L
E
S
G
G
F
R
S
L
L
I
N
A
V
E
A
S
C
I
R
T
R
E
L
----------------
26
PsiBlast_CBE
82.13
36%
-12
- C5 -
5BSH
2
?
E:
[6-277]
---------
I
I
P
I
P
A
D
S
Y
T
L
G
F
I
G
A
G
K
M
A
E
S
I
A
K
G
A
V
R
S
G
V
L
S
P
S
R
I
K
T
A
I
H
S
N
P
A
--
R
R
T
A
F
E
-
S
I
G
I
T
V
L
S
S
--
N
D
D
V
V
R
D
S
N
V
V
V
F
S
V
K
P
Q
L
L
K
D
V
V
L
K
L
K
P
L
L
T
K
D
-
K
-
L
L
V
S
V
A
A
G
I
K
M
K
D
L
Q
E
W
A
G
H
---
E
R
----
F
I
R
V
M
P
N
T
A
A
T
V
G
E
A
A
S
V
M
S
L
G
G
A
A
T
E
E
D
A
N
L
I
S
Q
L
F
G
S
I
G
K
I
-
W
K
A
D
-
D
K
Y
F
D
A
I
T
G
L
S
G
S
G
P
A
Y
I
Y
L
A
I
E
A
L
A
D
G
G
V
A
A
G
L
P
R
D
L
A
L
S
L
A
S
Q
T
V
L
G
A
A
S
M
A
T
Q
S
G
K
H
P
G
Q
L
K
D
D
V
T
S
P
G
G
T
T
I
A
G
V
H
E
L
E
K
A
G
F
R
G
I
L
M
N
A
V
V
A
A
A
K
R
S
Q
E
L
S
---------------
30
PsiBlast_CBE
81.43
36%
-13
- C5 -
5BSG
14
?
J:
[8-277]
-----------
P
I
P
A
D
S
Y
T
L
G
F
I
G
A
G
K
M
A
E
S
I
A
K
G
A
V
R
S
G
V
L
S
P
S
R
I
K
T
A
I
H
S
N
P
A
--
R
R
T
A
F
E
-
S
I
G
I
T
V
L
S
S
--
N
D
D
V
V
R
D
S
N
V
V
V
F
S
V
K
P
Q
L
L
K
D
V
V
L
K
L
K
P
L
L
T
K
D
-
K
-
L
L
V
S
V
A
A
G
I
K
M
K
D
L
Q
E
W
A
G
H
---
E
R
----
F
I
R
V
M
P
N
T
A
A
T
V
G
E
A
A
S
V
M
S
L
G
G
A
A
T
E
E
D
A
N
L
I
S
Q
L
F
G
S
I
G
K
I
-
W
K
A
D
-
D
K
Y
F
D
A
I
T
G
L
S
G
S
G
P
A
Y
I
Y
L
A
I
E
A
L
A
D
G
G
V
A
A
G
L
P
R
D
L
A
L
S
L
A
S
Q
T
V
L
G
A
A
S
M
A
T
Q
S
G
K
H
P
G
Q
L
K
D
D
V
T
S
P
G
G
T
T
I
A
G
V
H
E
L
E
K
A
G
F
R
G
I
L
M
N
A
V
V
A
A
A
K
R
S
Q
E
L
S
---------------