@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu19450: (2016-07-01 )
MAKNKKLFEYLSQHAETISSTWYETIEETDPNSIYASTDPVVIHNLKSQNLAFNYKINRIFIDDEDVYLPILKEWAFEVTQDQEHLKTPIHYIIREFVRVRDLYVSYVKEFVHLNQNTVKSEEAEDLYHALIKAFDLVIHIFIEEMYKNTSLQLQAQKDMITELSAPVIVLFHSVGLLPLIGDIDTVRAKLIMENTLHQCAKKKVTQLYIDLSGVAVIDTMVAHQLFSLIEALRLIGVSSTLSGIRPEIAQTAVQLGLSFEGISLRSTLASAIASDLKLKKV
Atome Classification :
(20 SA)
--------....-----.....10........20........30........40........50........----60------.------.......70-.....--------------....80.....---...90........100---.........110.......120.......130.......----140....----...150.......160.......170...----....180.......190-----------.........------------------------------------------------------------200.......210.......220.......230.......240.......250.....---------...260.--.-.---......270.......280------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------MAK
N
-----
K
K
L
F
E
Y
L
S
Q
H
A
E
T
I
S
S
T
W
Y
E
T
I
EETDPNSIYASTD
P
V
V
I
H
NLKSQ
N
L
A
F
N
Y
K
I
N
R
----
I
F
------I------DDED
V
Y
L
P
--
I
L
K
E
W
--------------
A
F
EVTQ
D
Q
E
H
L
---
K
T
P
I
H
Y
I
I
R
E
F
V
R
V
-----
R
D
L
Y
V
S
Y
V
K
E
F
V
HLNQNTVK
S
E
E
A
E
D
L
Y
H
A
L
I
K
A
F
D
L
V
I
----
H
I
F
I
E
E
M
----YKNT
S
L
Q
L
Q
A
Q
K
D
M
I
T
E
LSA
P
V
I
V
L
F
HSV----GL
L
P
LIG
D
I
D
T
V
R
A
K
-------------
L
I
M
E
N
T
L
H
Q
------------------------------------------------------------
C
A
K
K
K
V
T
Q
L
Y
I
DLS
G
V
A
V
I
D
T
M
V
A
H
Q
L
F
S
L
I
E
A
L
R
L
IG
V
S
S
T
LSGI
R
P
E
I
A
Q
-
T
A
V
Q
L---------GLSF--E--G-
I
---
S
L
R
S
T
L
A
S
A
I
A
SDLKLKKV------------------
3
PsiBlast_PDB
64.09
30%
-321
- C5 -
2VY9
-
?
A:
[32-102]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
L
L
H
N
------------------------------------------------------------
I
T
G
V
A
G
K
G
L
V
I
D
I
S
A
L
E
V
V
D
S
F
V
T
R
V
L
I
E
I
S
R
L
A
E
L
L
G
L
P
F
V
L
T
G
I
K
P
A
V
A
I
-
T
L
T
E
M
---------
G
L
D
L
--
R
--
G
-
M
---
A
------------------------------------
1
PsiBlast_PDB
63.72
30%
-325
- C5 -
3ZTB
-
?
A:
[32-102]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
L
L
H
N
------------------------------------------------------------
I
T
G
V
A
G
K
G
L
V
I
D
I
S
A
L
E
V
V
D
S
F
V
T
R
V
L
I
E
I
S
R
L
A
E
L
L
G
L
P
F
V
L
T
G
I
K
P
A
V
A
I
-
T
L
T
E
M
---------
G
L
D
L
--
R
--
G
-
M
---
A
------------------------------------
50
Fugue
63.18
21%
29
* C7 *
4B3X
3
IF2_THET8
A:
[1-363]
MAKVR
I
Y
Q
L
A
K
E
L
GME
T
Q
E
L
L
E
L
L
D
Q
M
G
V
A
Y
K
S
H
-
A
S
T
L
E
E
K
D
A
E
A
V
R
E
L
V
K
E
Q
R
G
L
Q
E
K
L
A
E
E
E
R
R
K
S
L
P
R
R
P
P
V
V
V
------
I
M
G
HVDH
G
K
T
T
L
L
D
Y
--
L
R
K
S
R
I
AEKEGGG
I
T
Q
H
VG
A
F
E
V
K
T
P
Q
G
T
V
V
F
I
D
T
P
G
H
E
A
F
T
T
-
I
R
Q
-----
R
G
A
K
V
A
D
I
A
V
I
V
I
A
A
D
D
G
I
M
P
Q
T
E
E
A
I
A
H
A
K
A
A
G
A
K
L
I
F
----
A
I
N
K
I
D
L
PQAD
P
E
K
V
K
R
Q
L
M
E
R
G
F
V
P
E
E
Y
G
G
D
A
I
V
I
P
I
S
A
KTGQ
G
V
Q
D
L
L
E
M
I
L
L
L
A
E
L
E
D
Y
R
A
D
PNAE
P
R
G
V
I
L
E
S
K
L
D
K
-------------------------------------------------------------
Q
A
G
I
I
A
N
M
L
V
Q
E
G
T
F
R
V
G
D
Y
V
V
A
G
E
A
Y
G
R
I
R
A
M
M
-----
D
A
D
G
N
Q
R
K
E
A
G
P
G
S
A
V
Q
V
L
GFQELPHA
G
D
V
V
--
E
--
W
-
V
---
P
D
L
E
A
A
K
E
I
A
E
E
R
K
E
E
R
K
A
R
E
E
E
E
K
A
RRPRTMAELLR
23
HHSearch
61.26
21%
-207
- C5 -
3ZXN
-
?
A:
[3-119]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
R
V
P
I
L
K
V
-
D
D
Y
----
W
V
V
A
I
E
E
T
L
-
D
Q
S
V
I
-------------
Q
F
K
E
E
L
L
H
N
------------------------------------------------------------
I
T
G
V
A
G
K
G
L
V
I
D
I
S
A
L
E
V
V
D
E
F
V
T
R
V
L
I
E
I
S
R
L
A
E
L
L
G
L
P
F
V
L
T
G
I
K
P
A
V
A
I
-
T
L
T
E
M
---------
G
L
D
L
--
R
--
G
-
M
---
A
T
A
L
N
L
Q
K
G
L
D
K
L
K
N
L
A
R
-------------------
2
PsiBlast_PDB
61.09
30%
-316
- C5 -
3ZXN
-
?
A:
[32-102]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
L
L
H
N
------------------------------------------------------------
I
T
G
V
A
G
K
G
L
V
I
D
I
S
A
L
E
V
V
D
E
F
V
T
R
V
L
I
E
I
S
R
L
A
E
L
L
G
L
P
F
V
L
T
G
I
K
P
A
V
A
I
-
T
L
T
E
M
---------
G
L
D
L
--
R
--
G
-
M
---
A
------------------------------------
42
Fugue
55.45
22%
-154
- C5 -
2VY9
-
?
A:
[6-119]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
I
L
K
V
D
D
Y
----
W
V
V
A
I
E
E
T
L
H
D
Q
S
V
I
-------------
Q
F
K
E
E
L
L
H
N
------------------------------------------------------------
I
T
G
V
A
G
K
G
L
V
I
D
I
S
A
L
E
V
V
D
S
F
V
T
R
V
L
I
E
I
S
R
L
A
E
L
L
G
L
P
F
V
L
T
G
I
K
P
A
V
A
I
-
T
L
T
-
E
M
--------
G
L
D
L
--
R
--
G
M
A
---
T
A
-
L
N
L
Q
K
G
L
D
K
L
K
N
L
A
R
-------------------
22
HHSearch
53.45
13%
-219
- C5 -
2KA5
-
Y1081_THEMA
A:
[13-124]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
F
P
Y
K
I
V
D
D
V
----
V
I
L
M
P
N
K
E
L
N
I
E
N
A
H
-------------
L
F
K
K
W
V
F
D
E
------------------------------------------------------------
F
L
N
K
G
Y
N
K
I
F
L
V
L
S
D
V
E
S
I
D
S
F
S
L
G
V
I
V
N
I
L
K
S
I
S
S
S
G
G
F
F
A
L
V
S
P
N
E
K
V
E
R
-
V
L
S
L
T
---------
N
L
D
R
-----
I
-
V
---
K
I
Y
D
T
I
S
E
A
M
E
E
V
R
R
----------------------
32
HHSearch
53.18
18%
-139
- C5 -
1SBO
-
Y1442_THEMA
A:
[10-110]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Q
D
D
K
----
A
I
V
R
V
Q
G
D
I
D
A
Y
N
S
S
-------------
E
L
K
E
Q
L
R
N
F
------------------------------------------------------------
I
S
T
T
S
K
K
K
I
V
L
D
L
S
S
V
S
Y
M
D
S
A
G
L
G
T
L
V
V
I
L
K
D
A
K
I
N
G
K
E
F
I
L
S
S
L
K
E
S
I
S
R
-
I
L
K
L
T
---------
H
L
D
K
-----
I
-
F
---
K
I
T
D
T
V
E
E
A
----------------------------
30
HHSearch
52.97
17%
-187
* C5 *
4DGF
3
?
A:
[16-128]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
K
V
V
P
L
G
V
----
E
I
Y
E
I
N
G
P
F
F
F
G
V
A
D
-------------
R
L
K
G
V
L
D
V
I
-------------------------------------------------------------
E
-
E
T
P
K
V
F
I
L
R
M
R
R
V
P
V
I
D
A
T
G
M
H
A
L
W
E
F
Q
E
S
C
E
K
R
G
T
I
L
L
L
S
G
V
S
D
R
L
Y
G
-
A
L
N
R
F
---------
G
F
I
E
-----
A
-
L
GEE
R
V
F
D
H
I
D
K
A
L
A
Y
A
K
L
L
---------------------
27
HHSearch
52.30
13%
-199
- C5 -
1TH8
1
SP2AA_GEOSE
B:
[8-114]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
V
K
Q
D
V
----
L
I
V
R
L
S
G
E
L
D
H
H
T
A
E
-------------
E
L
R
E
Q
V
T
D
V
------------------------------------------------------------
L
E
N
R
A
I
R
H
I
V
L
N
L
G
Q
L
T
F
M
D
S
S
G
L
G
V
I
L
G
R
Y
K
Q
I
K
N
V
G
G
Q
M
V
V
C
A
V
S
P
A
V
K
R
-
L
F
D
M
S
---------
G
L
F
K
-----
I
-
I
---
R
V
E
A
D
E
Q
F
A
L
Q
A
L
G
-----------------------
24
HHSearch
51.74
17%
-197
- C5 -
4HYL
3
?
A:
[10-114]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
E
Q
G
I
----
D
I
I
T
L
H
G
H
L
D
T
R
S
S
P
-------------
A
V
Q
A
A
V
L
P
R
------------------------------------------------------------
V
T
A
--
K
G
K
M
I
L
D
L
R
E
V
S
Y
M
S
S
A
G
L
R
V
L
L
S
L
Y
R
H
T
S
N
Q
Q
G
A
L
V
L
V
G
V
S
E
E
I
R
D
-
T
M
E
I
T
---------
G
F
W
N
-----
F
-
F
---
T
A
C
A
S
M
D
E
A
L
R
I
L
G
S
----------------------
47
Fugue
48.27
14%
-34
- C- -
4QYX
-
HSP31_YEAST
A:
[2-236]
----------
A
P
-----
K
K
V
L
L
A
L
T
S
Y
----
N
D
V
F
Y
S
D
G
A
K
T
G
V
F
-
V
V
E
A
L
H
P
F
N
T
F
R
K
E
G
F
E
V
D
F
V
S
E
T
G
K
----
F
G
------
W
------
D
E
H
S
L
A
K
D
--
F
L
N
G
Q
--------------
D
E
T
D
F
K
N
K
------
D
S
D
F
N
K
T
L
A
K
I
K
T
P
-----
K
E
V
N
---------------------------
A
D
D
Y
Q
I
F
F
A
S
A
G
H
G
T
L
F
D
Y
----
P
K
A
K
D
L
Q
D
I
A
S
E
--
I
Y
A
N
G
G
V
V
A
A
V
C
H
G
P
----
A
I
F
D
G
L
T
D
K
K
T
-
G
R
P
-------------
L
I
E
G
K
S
I
T
G
------------------------------------------------------------
F
T
D
V
G
E
T
I
L
-------
G
V
D
S
I
L
K
A
K
N
L
A
T
V
E
D
V
A
K
K
Y
G
--
A
K
Y
L
A
P
V
G
P
W
D
D
-
Y
S
I
T
D
---------
G
R
L
V
--
T
--
G
-
V
---
N
P
A
S
A
H
S
T
A
V
R
S
I
V
A
L
K
--------------------
35
HHSearch
48.09
21%
-177
- C5 -
4QTP
5
?
A:
[32-139]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
V
E
D
H
D
G
V
----
S
V
V
S
V
S
G
E
I
D
M
V
T
A
P
-------------
A
L
E
Q
A
I
G
A
V
------------------------------------------------------------
V
A
-
D
S
P
P
A
L
V
I
D
L
S
A
V
E
F
L
G
S
V
G
L
K
I
L
A
A
T
Y
E
K
L
G
K
E
T
-
G
F
G
V
V
A
R
G
P
A
T
R
R
-
P
I
H
L
T
---------
G
L
D
K
-----
T
-
F
---
P
L
Y
P
T
L
D
D
A
L
T
A
V
R
D
----------------------
51
Fugue
47.52
13%
16
- C7 -
6MHT
3
MTH1_HAEPH
A:
[1-327]
------MI
E
I
K
D
-----
K
Q
L
T
G
L
R
F
I
D
L
F
A
G
L
G
G
F
R
L
A
L
E
S
C
G
A
E
C
V
Y
S
N
E
W
D
K
Y
A
Q
E
V
Y
E
M
N
F
G
-
E
K
P
E
G
D
----
I
T
QVNEKT
I
------
P
D
H
D
I
L
C
A
--
G
F
P
C
Q
--------------
A
F
S
I
S
G
K
Q
K
G
F
---
E
D
S
R
G
T
L
F
F
D
I
A
R
I
-----
V
R
E
K
--
K
P
K
V
V
F
M
E
N
V
K
N
F
A
S
H
D
N
G
N
T
L
E
V
V
K
N
T
M
N
E
L
D
----
Y
S
F
H
A
K
V
----
L
N
A
L
D
Y
G
I
P
Q
K
R
E
R
I
Y
M
I
C
F
R
N
D
L
N
I
Q
N
F
----
Q
F
P
K
P
F
E
L
N
T
F
V
K
D
L
-------------
L
L
P
D
S
E
V
E
H
L
V
I
D
R
KDLVMTNQEIEQTTP
K
T
V
R
LGIVGKGGQGE
R
I
Y
S
TR
G
I
A
I
T
LSAYGGGIFAK
T
G
G
Y
L
V
N
---------------
G
K
---
T
R
K
L
H
P
R
E
C
A
R
V
M
G
Y
P
D
S
Y
K
V
H
-
P
S
T
S
Q
-
A
Y
K
Q
F
---------
G
N
S
V
-----
V
-
I
---
N
V
L
Q
Y
I
A
Y
N
I
G
S
S
L
N
F
K
P
Y
------------------
31
HHSearch
47.29
16%
-158
- C5 -
4DGH
8
?
A:
[16-127]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
L
P
R
E
L
----
A
V
Y
A
L
E
G
P
F
F
F
A
A
A
E
-------------
T
F
E
R
V
M
G
S
-------------------------------------------------------------
I
Q
-
E
T
P
Q
I
L
I
L
R
L
K
W
V
P
F
M
D
I
T
G
I
Q
T
L
E
E
M
I
Q
S
F
H
K
R
G
I
K
V
L
I
S
G
A
N
S
R
V
S
Q
-
K
L
V
K
A
---------
G
I
V
K
L
V
G
--
E
-
Q
---
N
V
Y
P
V
F
E
G
A
L
S
A
A
L
T
E
I
E
-------------------
26
HHSearch
47.29
14%
-182
- C5 -
1H4X
1
SP2AA_LYSSH
A:
[9-112]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
R
E
T
----
V
V
I
R
L
F
G
E
L
D
H
H
A
V
E
-------------
Q
I
R
A
K
I
S
T
A
------------------------------------------------------------
I
F
Q
G
A
V
T
T
I
I
W
N
F
E
R
L
S
F
M
D
S
S
G
V
G
L
V
L
G
R
M
R
E
L
E
A
V
A
G
R
T
I
L
L
N
P
S
P
T
M
R
K
-
V
F
Q
F
S
---------
G
L
G
P
-----
W
-
M
----
M
D
A
T
E
E
E
A
I
D
R
V
R
-----------------------
28
HHSearch
46.49
14%
-162
- C5 -
3NY7
2
A:
[9-118]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
V
V
V
D
V
P
D
D
V
----
L
V
L
R
V
I
G
P
L
F
F
A
A
A
E
-------------
G
L
F
T
D
L
E
S
R
------------------------------------------------------------
L
--
E
G
K
R
I
V
I
L
K
W
D
A
V
P
V
L
D
A
G
G
L
D
A
F
Q
R
F
V
K
R
L
P
-
E
G
C
E
L
R
V
C
N
V
E
F
Q
P
L
R
-
T
M
A
R
A
---------
G
I
Q
P
--
I
PG
R
-
L
---
A
F
F
P
N
R
R
A
A
M
A
D
L
------------------------
21
HHSearch
44.80
15%
-133
- C5 -
3PMD
2
?
A:
[6-152]
---------
A
T
K
-----
R
Y
L
C
L
Y
L
K
E
S
Q
E
K
F
I
S
N
W
K
K
R
I
L
V
H
E
H
-------
D
P
Y
K
N
-
E
I
I
K
N
G
T
H
L
L
H
V
F
T
M
----
Y
M
------
R
------
E
E
--
I
N
L
Q
--
D
I
E
D
I
--------------
S
K
K
I
A
Q
E
R
M
D
A
---
K
V
N
I
A
D
F
I
Y
N
T
N
E
G
-----
K
K
E
I
L
N
T
L
F
L
L
N
------
P
T
G
Q
E
C
K
V
V
I
E
Q
I
N
L
F
F
D
H
L
I
----
Y
S
T
I
Y
S
Y
----
Y
K
L
K
K
E
Y
I
H
S
Y
Y
E
L
K
K
K
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
43.95
15%
-112
- C5 -
3PMC
19
Y6575_BACAN
A:
[9-135]
-----------------
C
L
L
C
R
Y
L
K
E
R
Q
E
K
F
I
S
D
W
K
K
K
V
I
I
R
E
R
-------
D
P
Y
K
-
E
E
I
I
K
N
G
E
H
L
L
S
A
F
I
M
----
Y
L
------
K
------
E
E
I
--
S
L
Q
--
E
I
E
I
T
--------------
S
K
K
I
A
R
E
R
I
D
A
---
K
V
N
I
A
E
F
I
H
N
T
N
V
A
K
I
E
I
M
N
I
L
T
L
L
N
-----------
P
D
L
Q
Q
Y
Q
A
L
V
K
K
I
N
Q
F
F
D
H
L
I
----
Y
Y
T
V
H
S
Y
----
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
HHSearch
42.69
15%
-57
- C5 -
4ZVA
1
DOSC_ECOLI
A:
[20-149]
-----------------
A
K
A
A
E
I
A
V
A
H
A
H
Y
L
S
I
E
F
Y
R
I
V
R
I
D
P
H
A
E
E
F
L
-
S
N
E
Q
V
E
R
Q
L
K
S
A
---
M
E
R
W
I
I
N
----
V
L
------
S
------
A
Q
---
V
D
D
V
E
R
L
I
Q
I
--------------
Q
H
T
V
A
E
V
H
A
R
I
---
G
I
P
V
E
I
V
E
M
G
F
R
V
L
-----
K
K
I
L
Y
P
V
I
F
S
S
D
------
Y
S
A
A
E
K
L
Q
V
Y
H
F
S
I
N
S
I
D
I
A
M
----
E
V
M
T
R
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------