@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu20980: (2016-07-02 )
MERVKVIDSIMGSGKTTYIIKMMNEAPKNEHFIFITPYLDEVTRIKRSCTNRKFYEPKIHSEEGETLYKLDSLHKHLADNNDIVTTHALFSMANETTKELIYSGNYTLILDETMEVVKKLNISKDDLDMLFQNEWIKNNNGTIIWNDEQERNLNREYKGEFQTLKHLAKSKNLILHNESVLFWQFPADIFAQFKQVYNLTYLFDAQIQKYYYDINGIEYELYAVVKDNDSYKLMQHSRQFDKAKKDVLRHKIKIYEGDLNKIGDDYYALSKNWFEKRSVLHKRLKNNILNYYQNILKSKSKGNLWTTFKSHKSKLSGKGYTKGFLACNIKATNEYSHKRSLVYSINRFVNPAIDDYFRSKGIIINEDNFALSEMIQWIWRSAIRNGQDINIYVPSSRMRKLLMDWLENQR
Atome Classification :
(20 SA)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10..------..---------...-.20..-.-..--------.------.--.30........40.---..-.....50..----..--.-..--.--.60-......-.--.70--.-----.-..-...--..80........-----90........100-...-.-.--.---.110.....-----..120.......-------130.--......140..--...-..150.......160.......------------------170-.....------..180.-......190.....----..200-----------.......210.......220.......-230------...----.....240........250-.........260..-...-..270.-...-...280.-......290....-...300.--------------......310.......320.......330.......340.......-350..----------.....360----------....-...370----------------.-...-.....380...--------.-...390--...-....400.......410--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M
E
R
V
K
V
I
D
S
I
MGS------G
K
---------
T
T
Y
-
I
I
K
M
M
-N-EA--------P------K--NE
H
F
I
F
I
T
P
Y
L
D
E
V
---
T
R
-
I
K
R
SCT-NR----KF--Y-EP--K--IHS-EEGE
T
L
-
Y
--
K
L
---
D
-----
S
-
L
H
-
K
H
L--ADNN
D
I
V
T
T
H
A
L
-----
F
S
M
A
N
E
T
T
K
E
L
I
Y-SG
N
-
Y
-
T
--
L
---
I
L
D
E
T
M
E
V
V
-----
K
KLNI
S
K
D
D
L
D
M
-------
L
F
Q
N
--
E
WIKNNN
G
T
I
I
--WN
D
-
E
Q
E
RNL
N
R
E
YK
G
E
F
Q
T
L
K
H
L
A
K------------------SK
N
-
L
I
L
HN------E
S
V
L
F
W
-QF
P
A
D
I
F
A
Q
F
K
Q
V
Y----N
L
T
Y
L
-----------
F
D
A
Q
I
Q
K
Y
Y
Y
DING
I
E
Y
E
L
Y
A
V
V
KDND-
S
Y
-------
K
L
M
----
Q
H
S
R
Q
F
-
D
K
A
K
K
D
V
L
R
H
---
K
I
K
IYEG
D
L
N
KIGD-
D
Y
Y
-
A
L
S
K
N
W
-
F
E
K
-
R
S
V
L
H
K
R
-
L
K
N
N
I
L
N
Y
Y
Q
N
I
L
-KSKSKGN--------------
L
W
T
T
F
K
S
H
K
S
KLSGKGY
T
K
G
F
L
A
C
N
I
K
ATNEY
S
H
K
R
S
L
V
Y
S
I
N
R
FV-N
P
A
I
D
----------
D
Y
F
RSK
G
I
----------
I
INE-DN
F
A
------------------
L
-
S
E
M
-
I
Q
W
I
W
R
S
AIRN--------G-
Q
D
I
N
I
Y--V
P
S
-
S
R
M
R
K
L
L
M
D
W
LENQR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
Fugue
58.54
16%
35
- C4 -
4P0G
9
MLTF_PSEAE
A:
[7-435]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
P
T
A
L
E
R
V
Q
K
E
------
G
V
---------
L
R
V
-
I
T
R
-------------------------
N
S
P
A
T
Y
F
Q
D
R
N
G
E
T
G
F
E
Y
E
-
L
A
K
R
F
A
-
E
R
----
L
G
--
V
-
E
L
--
K
--
I
E
T
-
A
D
N
--------
L
---
D
-----
D
-
L
Y
-
A
Q
L
--
S
R
E
G
G
P
A
L
A
A
A
G
-----
L
T
P
G
R
E
D
D
A
S
V
R
Y
-
S
H
T
-
Y
--------------
L
D
V
-----
T
P
Q
I
I
Y
R
N
G
Q
Q
R
-------
P
T
R
P
--
E
D
L
V
G
K
R
I
M
V
L
--
K
G
S
-
S
H
A
E
Q
L
-
A
E
L
K
K
Q
Y
P
E
L
K
Y
-
E
E
------------------
S
D
A
-
V
E
V
V
D
------
L
L
R
M
V
D
-
V
G
D
I
D
L
T
L
V
D
S
N
E
L
----
A
M
N
Q
V
-----------
Y
F
P
N
V
R
V
A
F
D
--
F
G
E
A
R
G
L
A
W
A
L
P
G
G
D
-
D
D
-------
S
L
M
----
N
E
V
N
A
F
L
D
Q
A
K
K
-------------
E
G
L
L
Q
R
L
K
D
-
R
Y
Y
-
G
H
V
D
V
L
G
Y
V
G
-
A
Y
T
F
A
Q
H
-
L
Q
Q
R
L
P
R
Y
E
S
H
F
K
-
Q
S
G
K
Q
L
D
TD
W
R
L
L
A
A
I
G
Y
Q
E
S
L
W
Q
P
G
A
T
S
K
T
G
V
R
G
L
M
M
L
T
N
R
T
A
Q
A
M
G
V
S
N
R
L
D
P
K
Q
S
I
Q
G
G
S
K
Y
F
V
-
Q
I
R
S
E
LPESIKE
P
D
R
S
W
F
A
L
A
A
Y
----------
N
I
G
G
-
A
H
L
E
D
A
R
K
M
A
E
K
E
GLNPNK
W
L
D
V
-
K
K
M
-
L
P
R
L
A
Q
K
Q
W
Y
A
KTRYGYAR
G
-
G
E
T
V
H
F
--
V
Q
N
-
V
R
R
Y
Y
D
I
L
T
W
V
T
Q
P
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
Fugue
44.91
15%
-12
- C2 -
4MND
4
DIPPS_ARCFU
A:
[40-457]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
M
K
A
V
I
L
A
A
G
L
G
G
------
G
V
PKPLVRVGG
C
E
I
-
I
L
R
T
M
-
K
-
L
L
--------
S
------
P
HV
S
E
F
I
I
V
A
S
R
Y
A
D
D
I
---
D
A
F
L
K
D
K
G
F
-
N
Y
----
K
I
--
V
-
R
H
--
D
----
R
-
P
E
K
G
N
G
-
Y
--
S
L
---
L
-----
V
-
A
K
-
N
H
V
--
E
D
R
F
I
L
T
M
G
D
H
V
-----
Y
S
------
Q
Q
F
I
E
-
K
A
V
-
R
-
G
E
G
V
---
I
A
D
R
E
P
R
F
V
DIGEA
T
K
I
R
V
E
D
G
R
V
A
K
-------
I
G
K
D
LR
E
F
D
C
V
D
T
G
F
F
V
--
L
D
D
-
S
I
F
E
H
A
E
K
L
R
D
R
E
E
I
P
L
S
E
I
V
K
L
A
R
L
P
V
T
Y
V
D
G
E
L
W
M
D
V
D
T
K
E
-
D
V
R
R
A
------
N
R
A
L
V
S
-
A
A
V
G
D
G
F
I
S
R
K
I
N
R
----
K
I
S
T
R
-----------
I
S
A
A
I
V
N
---
K
V
N
P
N
Q
M
T
L
I
S
F
L
V
G
A
F
-
S
A
-------
L
A
S
----
F
F
S
-----
I
P
L
A
G
L
L
Y
Q
---
F
S
S
I
L
D
G
C
D
G
E
I
A
R
-
A
S
L
-
K
M
S
K
K
G
-
G
Y
V
-
D
S
I
L
D
R
F
-
V
D
F
L
F
L
A
I
I
A
L
L
Y
-
P
K
T
A
T
V
A
--------------
M
F
A
I
F
G
S
V
M
V
S
Y
T
S
E
K
Y
K
A
E
F
G
E
S
I
R
V
L
N
Y
I
P
G
K
R
D
E
R
I
F
L
I
M
I
F
C
-
L
L
S
A
I
----------
S
L
----------------------------------------------
Q
W
-
I
F
W
M
F
L
F
V
A
A
I
--------
S
-
L
T
R
V
V
V
--
T
L
L
-
A
V
L
V
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
Fugue
43.16
19%
51
- C4 -
5A07
3
KTR4_YEAST
A:
[40-434]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
H
D
A
E
V
L
D
S
I
M
D
R
L
H
E
PLY
E
K
---------
D
T
F
-
D
P
N
E
V
-
L
-
A
E
--------
N
------
K
--
Q
L
Y
E
E
F
L
---
L
Q
E
I
---
S
E
-
P
K
V
D
N
L
-
V
R
----
S
---
G
-
D
P
--
L
--
A
G
K
-
A
K
G
T
I
L
-
S
LV
R
N
---
S
-----
D
-
L
E
-
D
I
I
--
S
S
I
Q
Q
L
E
E
E
Y
N
K
NFG
Y
P
Y
T
F
L
N
D
E
E
F
T
D
E
F
-
K
D
G
-
I
-
K
--
S
---
I
L
P
K
D
-
R
V
V
-----
E
F
G
T
I
G
P
D
N
W
N
M
PDSID
R
E
R
Y
D
Q
--
E
M
D
K
M
S
K
E
N
I
Q
--
Y
A
E
V
E
S
Y
H
N
M
C
R
F
Y
S
K
E
F
Y
H
H
P
L
L
S
K
------------------
Y
K
Y
-
V
W
R
L
E
------
P
N
V
N
F
Y
C
K
I
N
Y
D
V
F
-
Q
F
M
N
K
N
----
D
K
I
Y
G
-----------
F
V
L
N
L
Y
D
S
P
Q
T
I
E
T
L
W
T
S
T
M
D
F
V
E
E
H
P
-
N
Y
LNVNGA
F
A
W
L
K
DNS
Q
N
P
K
N
Y
-
D
Y
T
Q
G
Y
S
T
C
H
FWT
N
F
E
I
V
D
L
D
F
L
R
-
S
E
-
P
Y
E
-
K
Y
M
Q
Y
L
-
E
E
K
-
G
G
F
Y
Y
E
R
-
W
G
D
A
P
V
R
S
L
A
L
A
L
F
A
D
K
S
S
I
H
--------------
W
F
R
D
I
G
Y
H
H
T
P
Y
T
N
---------
C
P
T
C
P
A
D
S
-----------
D
R
C
N
-
G
N
C
V
P
----------
G
K
F
T
P
W
---------------
S
-
D
L
D
N
------------------
Q
-
N
C
Q
-
A
T
W
I
R
H
S
M
--
S
--------
E
-
E
E
L
E
M
Y
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
Fugue
41.12
21%
58
- C4 -
4QOY
-
?
C:
[5-886]
PNDVD
P
I
E
T
R
D
W
L
Q
A
I
E
S
V
I
R
E
EG
V
E
R
A
Q
Y
L
I
D
Q
L
L
A
E
A
R
KGGVNVAAGTGISNYINTIPVEEQPEYPGN
L
E
L
E
R
R
I
R
S
A
I
R
W
N
A
I
M
T
V
L
R
A
S
K
K
DLEL
G
G
H
M
A
S
F
Q
S
S
A
T
I
Y
D
V
C
F
N
HFFRARNEQDGGDLVYFQGHI
S
P
G
V
Y
A
R
A
F
L
E
GRLT
Q
E
Q
L
D
N
FRQEVHGNGLSSYPHPKLMPEFWQFPTVSMG
L
G
P
I
G
A
I
Y
Q
A
K
F
L
K
Y
L
E
H
R
GLKDTSK
Q
T
V
Y
A
F
L
G
-----
D
G
E
M
D
E
------
P
E
---------
S
K
G
-
A
I
T
I
A
-
T
-
R
E
--------
K
------
L
--
D
N
L
V
F
V
I
N
C
N
L
Q
------
R
-
L
D
G
P
V
T
G
N
G
----
K
I
--
I
-
N
E
L
E
G
--
I
F
E
-
G
A
G
W
N
V
-
I
--
K
V
MWG
S
-----
R
-
W
D
-
E
L
L
--
R
K
D
----
T
S
G
K
L
-----
I
Q
L
M
N
E
T
V
---------------------
D
G
D
Y
Q
T
F
-----
K
S
K
D
G
A
Y
V
R
E
H
F
-------
F
G
K
Y
--
P
E
T
A
A
L
V
A
D
----
W
T
D
-
E
Q
I
W
A
L
N
R
-------------------------------------
G
G
H
D
---------------
P
K
K
I
Y
A
A
F
K
K
A
Q
E
TKG
K
A
T
V
I
-----------
L
A
H
T
I
K
G
Y
G
M
G
D
A
A
I
A
H
Q
V
K
K
M
--------------------------
N
M
-
D
G
V
R
H
I
R
D
R
F
---
N
V
P
V
S
D
A
D
I
E
K
L
P
----
Y
-
I
T
F
P
E
G
-
S
E
E
-
H
T
Y
L
H
A
Q
-
R
Q
K
L
--------------
H
G
Y
--------------
L
P
S
R
Q
P
N
F
T
E
K
L
E
L
P
S
L
-
Q
D
F
G
A
L
L
E
E
Q
S
K
E
I
S
T
T
I
A
F
V
R
A
L
N
V
M
L
K
N
K
S
I
K
----------
D
R
L
V
P
--
I
----------
I
A
D
E
A
R
T
F
G
------------------
M
-
E
G
L
-
F
R
Q
I
--------------------
G
I
Y
--
S
P
N
-
G
K
E
D
E
K
G
Q
I
L
Q
E
G
I
N
E
L
G
A
G
C
S
W
L
A
A
A
T
SYSTNN
L
P
M
I
P
F
Y
I
Y
YSMFGFQRI
G
D
L
C
W
A
A
G
D
Q
Q
A
R
G
F
L
I
GGTSGRTTLNGEGLQHEDGH
S
H
I
Q
S
L
T
IPN
C
I
S
Y
D
P
AY
A
Y
E
V
A
V
I
M
H
D
G
L
E
R
M
YGEKQEN
V
Y
Y
Y
I
T
T
L
NEN
Y
H
M
P
A
M
PEGA
E
E
G
I
R
K
GIYKL
E
T
I
E
G
SK
G
K
V
Q
L
L
G
S
G
SI
L
R
H
V
R
E
A
A
E
I
L
A
KDYG
V
G
S
D
V
Y
S
V
TS
F
T
E
L
A
R
D
G
Q
D
C
E
R
W
N
M
L
H
PLET
P
R
V
P
Y
I
A
Q
V
M
ND
A
P
A
V
A
S
T
DYM
K
L
F
A
E
Q
VRTYVPAD
D
Y
R
V
L
GTD
G
F
G
R
S
D
S
R
E
N
L
R
H
H
F
EVD
A
S
Y
V
V
V
A
A
L
G
E
L
A
K
R
GEID
K
K
V
V
A
D
A
I
A
K
F
NIDADKVNPRLA
11
PsiBlast_PDB
39.37
40%
-240
- C5 -
3WAG
-
?
A:
[87-114]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
W
-
Q
Y
I
H
D
V
F
A
Q
Y
S
Q
I
Y
----
E
--
Y
M
-----------
A
D
S
T
M
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
Fugue
38.37
12%
34
- C4 -
4INA
-
?
A:
[2-394]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
V
L
Q
I
----
G
A
------
G
G
---------
V
G
G
-
V
V
A
H
K
M
A
M
N
R
--------
E
------
V
--
F
S
H
I
T
L
A
S
R
T
L
S
K
C
---
Q
E
-
I
A
Q
S
I
K
-
A
K
------------------------------------------------------
G
Y
G
E
I
D
I
T
T
V
-----
D
A
D
S
I
E
E
L
V
A
L
I
N
-
E
V
K
-
P
-
Q
--
I
---
V
L
N
-------------
I
A
L
P
Y
Q
D
L
T
I
-----------
M
-
E
A
C
L
R
T
G
V
P
Y
L
D
T
A
N
Y
-
E
H
P
D
L
A
K
F
E
Y
K
E
Q
W
A
F
H
D
R
Y
K
E
------------------
K
G
V
M
A
L
L
G
S
GFDPG
V
T
N
V
F
C
A
-
Y
A
Q
K
H
Y
F
D
E
I
H
E
I
D
----
I
L
D
C
N
AGDHGYPFATN
F
N
P
E
I
N
L
R
E
V
S
S
K
G
R
Y
W
E
N
G
E
W
I
E
T
E
P
M
E
I
M
------
Q
V
W
----
D
Y
P
E
V
G
-
P
K
D
S
Y
L
L
Y
H
E
---
E
L
E
S
L
V
R
N
I
K
G
L
K
R
I
R
F
F
M
T
F
G
Q
S
Y
-
L
T
H
M
R
C
L
E
N
V
G
M
L
R
I
D
E
I
E
V
N
G
----
C
K
V
V
P
I
Q
--------------
V
L
K
A
L
L
P
D
P
A
S
L
A
S
R
T
K
G
K
T
N
I
G
C
Y
I
K
G
I
K
E
--
G
K
A
R
T
I
Y
I
Y
N
V
C
D
-
H
E
S
C
Y
----------
R
E
V
N
A
Q
A
I
----------
S
Y
T
T
-
G
V
P
A
M
-----------------
I
G
A
K
L
M
L
E
G
K
W
S
G
K
G
V
F
--------
N
M
E
E
L
D
P
D
---
P
F
M
D
E
L
N
K
Q
G
L
P
W
E
V
K
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
38.11
17%
-24
- C6 -
2Z83
-
A:
[188-293]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
M
T
V
L
D
L
H
P
G
S
------
G
K
---------
T
R
K
I
L
P
Q
I
I
-
K
-
D
A
I
-------
Q
------
Q
--
R
L
R
T
A
V
L
A
P
T
R
V
V
A
---
A
E
-
M
A
E
A
L
R
-
G
L
----
P
V
--
R
-
Y
Q
--
T
-------------------------------------
G
N
E
I
V
D
V
M
C
H
A
T
-----
L
T
H
R
L
M
S
P
N
-----
V
P
N
-
Y
N
L
--
F
---
V
M
D
E
A
H
F
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
37.38
40%
-260
- C5 -
3WAD
-
?
A:
[87-114]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
W
-
Q
Y
I
H
D
V
F
A
Q
Y
S
Q
I
Y
----
E
--
Y
M
-----------
A
D
S
T
M
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
35.54
21%
-123
- C3 -
1YF9
-
?
A:
[24-106]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
C
N
S
T
R
K
V
Y
-
P
S
D
T
V
A
E
--------------
F
W
V
E
F
K
G
P
E
----
G
T
P
Y
E
D
G
T
W
M
L
H
V
Q
L
P
S
D
Y
P
F
K
S
P
S
I
G
F
C
N
R
I
L
-
H
P
N
V
D
----------
E
--
R
S
G
S
V
----------
C
L
D
V
-
I
N
Q
T
------------------
W
-
T
P
M
-
Y
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
34.88
16%
-56
- C6 -
2JLQ
-
A:
[20-122]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
L
T
I
M
D
L
H
P
G
A
------
G
K
---------
T
K
R
-
I
L
P
S
I
-
V
-
R
E
A
L
------
L
------
R
--
R
L
R
T
L
I
L
A
P
T
R
V
V
A
---
A
E
-
M
E
E
A
L
R
-
G
L
----
P
I
--
R
-
Y
Q
--
T
--
P
---
A
-
V
----
K
--
S
---------------
D
H
T
--
G
R
E
I
V
D
L
M
C
H
A
T
-----
F
T
T
R
L
L
S
S
---
T
R
-
V
P
N
-
Y
N
L
--
I
---
V
M
D
E
A
H
F
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
Fugue
34.56
11%
5
- C4 -
1NIJ
-
YJIA_ECOLI
A:
[2-318]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N
P
I
A
V
T
L
L
T
G
F
L
G
A
------
G
K
---------
T
T
L
-
L
R
H
I
L
-
N
-
E
---------
Q
------
H
--
G
Y
K
I
A
V
I
E
N
E
F
G
E
V
---
S
-------------------
V
-
D
D
--
Q
--
L
I
G
-
D
R
A
T
Q
I
-
K
--
T
L
---
T
-----
N
-
G
C
-
I
C
C
--
S
R
S
N
E
L
E
D
A
L
L
D
-----
L
L
D
N
L
D
K
G
N
------
I
Q
-
F
-
D
--
R
---
L
V
I
E
C
T
G
M
A
-----
D
---------------------------------------------------------------------------------------------------------
P
G
P
I
I
Q
T
F
F
S
-----------------------
H
E
V
L
C
Q
R
--------
Y
L
L
D
G
V
I
A
L
V
D
-
A
V
-------
H
A
D
----
E
Q
M
N
Q
F
-
T
I
A
Q
S
Q
V
G
Y
A
---
D
R
I
L
L
T
K
--
T
D
V
A
G
-
E
A
E
-
K
L
H
E
R
L
-
A
R
I
-
N
A
R
A
P
V
Y
-
T
V
T
H
G
D
I
D
L
G
L
L
F
-
N
T
N
G
F
M
L
--------------
E
E
N
V
V
S
T
K
P
R
F
H
F
I
A
D
K
Q
N
D
I
S
S
I
V
V
E
L
D
Y
P
V
D
-
I
S
E
V
S
R
V
M
E
N
L
L
-
L
E
S
A
D
----------
K
L
L
R
Y
K
G
M
L
WIDGEP
N
R
L
L
F
Q
G
-
V
Q
R
L
------------------
Y
-
S
A
D
-
W
D
R
P
W
G
D
E
K
P
H
--------
S
-
T
M
V
F
I
G
I
Q
L
P
E
-
E
E
I
R
A
A
F
A
G
L
R
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
33.91
17%
-34
- C6 -
2Z0M
-
?
A:
[34-141]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
V
V
R
A
K
T
G
S
------
G
K
---------
T
A
A
-
Y
A
I
P
I
-
L
-
E
----------------
L
--
G
M
K
S
L
V
V
T
P
T
R
E
L
T
---
R
Q
-
V
A
S
H
I
R
-
D
I
----
G
R
--
Y
-
M
D
T
K
V
--
A
E
V
-
Y
G
G
----
M
--
P
Y
---
K
-----
A
-
Q
I
-
N
R
V
--
R
N
A
D
I
V
V
A
T
P
G
R
-----
L
L
D
L
W
S
K
G
--
V
I
D
L
S
S
F
-
E
-
I
--
V
---
I
I
D
E
A
D
L
M
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
31.36
17%
25
- C6 -
2PL3
4
DDX10_HUMAN
A:
[64-185]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
L
G
A
A
K
T
G
S
------
G
K
---------
T
L
A
-
F
L
V
P
V
-
L
-
E
A
L
Y
R
L
QWTS
T
------
D
--
G
L
G
V
L
I
I
S
P
T
R
E
L
A
---
Y
Q
-
T
F
E
V
L
R
-
K
V
----
G
K
--
N
-
H
D
--
F
S
A
G
L
I
-
I
G
G
--------
L
---
K
-----
H
-
E
A
-
E
R
I
--
N
N
I
N
I
L
V
C
T
P
G
R
-----
L
L
Q
H
M
D
E
T
V
S
F
H
A
-
T
D
L
-
Q
-
M
--
L
---
V
L
D
E
A
D
R
I
L
-----
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
31.21
13%
-21
- C6 -
3TBK
1
A:
[22-173]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
I
C
A
P
T
G
C
------
G
K
---------
T
F
V
-
S
L
L
I
C
-
E
-
H
H
--------
L
K
KFPCG
Q
--
K
G
K
V
V
F
F
A
N
Q
I
P
V
Y
---
E
Q
-
Q
A
T
V
F
S
-
R
Y
----
F
E
RL
G
-
Y
N
--
I
--
A
S
I
-
S
G
A
----
T
--
S
D
---
S
-----
V
S
V
Q
-
H
I
I
--
E
D
N
D
I
I
I
L
T
P
Q
I
-----
L
V
N
N
L
N
N
G
A
-
I
P
S
-
L
S
V
-
F
T
L
--
M
---
I
F
D
E
C
H
N
T
S
-----
K
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
30.99
12%
-53
- C6 -
4CBH
-
POLG_CSFVA
A:
[220-476]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
R
Q
I
T
L
A
T
G
A
------
G
K
---------
T
T
E
-
L
P
R
S
V
-
I
-
E
E
I
-------
G
------
R
--
H
K
R
V
L
V
L
I
P
L
R
A
A
A
---
E
S
-
V
Y
Q
Y
M
R
-
Q
K
----
H
P
--
S
-
I
A
--
F
--
N
L
R
-
I
-
G
----
E
---------------
M
K
-
E
G
D
--
M
A
T
G
I
T
Y
A
S
Y
G
Y
-----
F
C
Q
M
S
Q
P
K
L
R
-
A
A
-
M
V
E
Y
S
-
F
--
I
---
F
L
D
E
Y
H
C
A
T
-----
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
30.60
21%
0
- C- -
4F4W
-
DPO4_SULAC (first)
A:
[214--100]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
K
I
T
G
K
------
A
K
---------
A
L
Y
-
L
L
K
L
A
-
Q
-
D
E
--------
Y
------
N
--
E
P
I
R
T
R
V
R
K
S
I
G
R
I
---
V
T
-
M
K
R
N
S
R
-
N
L
----
E
E
--
I
-
K
P
--
Y
--
L
F
R
-
A
I
E
E
S
Y
-
Y
--
K
L
---
D
KRIPK
A
-
I
H
V
V
A
V
--
T
E
D
L
D
I
V
S
R
G
R
T
-----
F
P
H
G
--
I
S
K
E
T
A
Y
-
S
E
S
-
V
-
K
--
L
L
Q
K
I
L
E
E
D
E
R
K
I
-----
R
R
I
G
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
HHSearch
30.31
14%
-7
- C6 -
2YKG
3
A:
[31-200]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
I
C
A
P
T
G
C
------
G
K
---------
T
F
V
-
S
L
L
I
C
-
E
-
H
H
--------
L
K
KFPQG
Q
--
K
G
K
V
V
F
F
A
N
Q
I
P
V
Y
---
E
Q
-
N
K
S
V
F
S
-
K
Y
F
ERH
G
Y
--
R
-
V
T
--
G
---
I
S
-
G
A
T
----
A
--
E
N
---
V
-----
P
-
V
E
-
Q
I
V
--
E
N
N
D
I
I
I
L
T
P
Q
I
-----
L
V
N
N
L
K
K
G
-
T
I
P
S
-
L
S
I
F
T
-
L
--
M
---
I
F
D
E
C
H
N
T
S
-----
K
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
HHSearch
30.14
15%
-70
- C6 -
3O8B
2
?
A:
[233-330]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
V
A
H
L
H
A
P
T
G
S
------
G
K
---------
S
T
K
-
V
P
A
A
Y
-
A
-
A
----------------
Q
--
G
Y
K
V
L
V
L
N
P
S
V
A
A
T
---
L
G
-
F
G
A
Y
M
S
-
K
A
----
H
G
--
I
-
D
P
--
N
--
I
R
---
T
G
----
V
--
R
---------------
T
I
T
--
T
G
A
P
V
T
Y
S
T
Y
G
K
-----
F
L
A
D
G
G
C
S
----
G
-
G
A
Y
-
D
-
I
--
I
---
I
C
D
E
C
H
S
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
29.99
15%
-29
- C6 -
3OIY
2
?
A:
[39-153]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
T
M
V
A
P
T
G
V
------
G
K
---------
T
T
F
-
G
M
M
T
A
-
L
-
W
L
A
-------
R
------
K
--
G
K
K
S
A
L
V
F
P
T
V
T
L
V
---
K
Q
-
T
L
E
R
L
Q
-
K
L
----
A
D
--
E
K
V
K
--
I
--
F
G
F
-
Y
S
S
-
M
K
K
E
--
E
K
---
E
-----
K
-
F
E
-
K
S
F
E
E
D
D
Y
H
I
L
V
F
S
T
Q
F
-----
V
S
K
N
R
E
K
L
-
S
--
Q
-
K
R
F
-
D
-
F
--
V
---
F
V
D
D
V
D
A
V
L
-----
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
28.93
11%
-4
- C6 -
2OCA
-
UVSW_BPT4
A:
[131-247]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
L
N
L
P
T
S
A
------
G
R
---------
S
L
I
-
Q
A
L
L
A
-
R
-
Y
Y
L
E
------
N
------
Y
--
E
G
K
I
L
I
I
V
P
T
T
A
L
T
---
T
Q
-
M
A
D
D
F
V
-
D
Y
----
R
L
--
F
-
S
H
--
A
--
M
I
K
K
I
G
G
----
G
--
A
S
---------
K
-
D
D
-
K
Y
K
--
N
D
A
P
V
V
V
G
T
W
Q
T
-----
V
V
K
Q
P
K
E
W
F
-----
S
Q
F
-
G
-
M
--
M
---
M
N
D
E
C
H
L
A
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------