@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu21150: (2016-07-03 )
MKLDTVKIKGLFSRVLNNKMDGTDKADIQTYIKKVFGDGGTTPDPSMLHQFNNLVVEQADEIAKPKVTQLLSLLANVQQEKRGNIKEIKIPKKNKAKVIWSATGSGVDLVRVEGQETVPAVPKTMSTGFYYEPLDLVTDSIVYFNKLVNDIADAKVRLYLDKIHQLTASAITAGKIPAKNVQTGSNLTLQQYNKVASVLQRYGGKPIFVADTLLIDYFAFQQGTDSTFKNFLTEEVKGELLTALNPTTIGRTTAVNLTNPFTDDTNSKVELPVNKGYMFAGGVSQKPFSVVEYGGLRQLTEQDIEDERIKMKIVQDASVNLLFGEAIGIIEEQAAVSI
Atome Classification :
(20 SA)
--------.........10........20....---....30--------........---40........50..--------......60.-------.......70........80....--....90........100......----.110.......120...-....130.......140..--------.----....150...----....160.......170--..-----......------180.......190.--------------....---..200........210-------------.......-------------------------.220.......230------.........240.......250........260.......---------270.......280....----...290.......300---........-----310....--------------...320.......330......-----------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------MKL
D
T
V
K
I
K
G
L
F
S
R
V
L
NNKMDGT
D
K
---
A
D
I
Q
T
Y
--------
I
K
K
V
FGDG---GTTP
D
P
S
M
L
H
Q
F
N
N
--------
L
V
V
E
Q
A
D
E
I-------AK
P
K
V
T
Q
L
L
S
L
L
A
N
V
Q
Q
E
KRGNI--
K
E
I
KIPKKNK
A
K
V
I
W
SATGS
G
V
D
----
L
V
R
VEGQETVPAVPKTM-STG
F
Y
YE
P
L
D
L
V
T
D
S
I
V
Y
F
--------
N
----
K
L
V
N
D
I
AD
A
K
----
V
R
L
Y
L
D
K
I
H
Q
L
T
A
S
AI---TA-----GKIPAK------NVQTGSN
L
T
L
Q
Q
Y
N
--------------
K
V
A
S
---
V
L
Q
-
R
YGG
K
P
I
F
V
A
D
--------------
T
L
L
I
D
Y
F
-------------------------
A
FQQGT
D
S
T
F
K
N
--------
F
L
T
E
E
VKG
E
L
L
TALNPTTIG
R
-
T
T
A
V
N
LTNPFTDDTN
S
K
V
---------
E
L
PVNK
G
Y
M
F
AGGVSQK----PF
S
V
V
EYG
G
L
R
Q
L
T
E
----QDIEDE
R
I
-----
K
M
K
I
VQD--------------AS
V
N
L
L
FGEAI
G
I
I
E
E
Q
AAVSI-----------------------------------------------------------------------------
43
Fugue
63.89
19%
-45
* C3 *
4CZB
1
NAH1_METJA
A:
[1-415]
----M
E
L
M
M
A
I
G
Y
L
G
L
A
L
V
L
G
S
L
V
A
K
I
A
E
K
L
K
I
---
P
D
I
P
L
L
--------
L
L
L
G
L
I
I
G
PFL
Q
I
I
P
S
D
S
A
M
E
I
F
E
Y
A
G
P
I
G
L
I
F
I
L
L
G
G
A
F
T
M
RISLLKR
V
I
K
T
V
V
R
L
D
T
I
T
F
L
I
T
L
L
I
S
G
F
I
F
N
M
V
L
N
L
P
Y
T
S
P
V
G
Y
L
F
G
A
I
T
A
A
T
D
P
A
T
L
I
P
V
F
S
R
V
R
T
N
P
E
V
A
I
T
L
E
A
E
S
I
F
N
D
P
L
G
I
V
S
T
S
V
I
L
G
L
F
GLFSSS
N
----
P
L
I
D
L
I
T
L
A
G
G
A
I
V
V
G
L
L
L
A
K
I
Y
E
K
I
I
I
H
C
---
D
F
-----
H
E
Y
V
A
P
------
L
V
L
G
G
A
M
L
L
L
Y
V
G
D
D
L
L
P
S
I
CG
Y
G
F
S
G
Y
M
A
V
A
---
I
M
G
-
L
Y
L
G
D
A
L
F
R
A
D
DID
Y
K
Y
I
V
S
F
C
D
D
L
S
L
L
A
R
V
F
-------------------------
I
F
V
F
L
G
A
C
I
K
L
S
--------
M
L
E
N
Y
F
I
P
G
L
L
V
A
L
G
S
I
F
L
A
R
-
P
L
G
V
F
L
G
L
I
-----
G
S
K
H
---------
S
F
K
E
K
L
Y
F
A
L
E
G
P
R
G
V
V
----
P
A
A
L
A
V
T
V
G
I
E
I
L
K
N
----
A
D
K
I
P
A
S
I
T
K
Y
IT
P
T
D
I
A
G
T
--------------
I
I
I
G
T
F
M
T
I
L
L
S
V
I
L
E
A
S
W
A
G
M
L
A
L
K
L
LGE---------------------------------------------------------------------
46
Fugue
53.30
20%
59
* C5 *
4X7P
8
?
A:
[1-493]
M
K
K
I
F
M
M
V
H
E
L
D
V
N
K
-
G
G
M
T
S
S
M
F
N
R
S
K
E
F
Y
D
A
DI
P
A
D
I
V
T
F
D
Y
K
GN
Y
D
E
I
I
K
A
L
K
K
Q
---
G
K
M
D
R
R
T
K
M
Y
N
------------
V
F
E
Y
F
K
Q
I
-------
S
N
N
K
H
F
K
S
N
K
L
L
Y
K
H
I
S
E
R
L
K
N
T
--
I
E
I
E
-
E
S
K
G
I
S
R
Y
F
D
I
T
T
G
T
Y
I
A
----
Y
I
R
K
S
K
S
E
K
V
I
D
F
F
K
D
N
-
K
R
I
E
R
F
S
F
I
D
N
K
V
H
M
K
E
T
F
--------
N
VDNK
V
C
Y
Q
V
F
Y
D
E
K
----
G
Y
P
Y
I
S
R
N
I
N
A
N
N
G
A
V
---
G
K
-----
T
Y
V
L
V
N
------
K
K
E
F
K
N
N
L
A
L
C
V
Y
Y
--------------
L
E
K
L
---
I
---
K
D
S
K
D
S
I
M
I
C
D
GP------------
G
S
F
P
K
M
F
N
TNHKN
A
Q
K
Y
G
V
I
HVNHHENFDDTG
A
F
K
K
S
E
K
Y
I
I
E
N
A
NKIN
G
V
I
V
L
T
E
A
Q
R
L
D
I
L
N
Q
F
D
V
E
N
I
F
T
I
S
N
F
V
K
I
H
N
A
P
K
H
F
Q
T
E
K
I
V
G
H
I
S
R
MVP
T
K
R
I
D
L
L
I
E
V
A
E
L
V
V
K
K
DNA
V
K
F
H
I
Y
G
E
G
S
V
K
D
K
I
A
----
K
M
I
E
D
K
N
L
-----
E
R
N
V
F
L
K
GYTTT
P
Q
K
C
L
E
D
FK
L
V
V
S
T
S
Q
Y
E
G
Q
G
L
S
M
I
E
A
M
I
S
K
R
P
V
V
A
F
DIKYGPSDFIEDNKNGYLIENHN
I
N
D
M
A
D
K
I
L
Q
L
V
N
N
D
V
L
A
A
E
F
G
S
K
A
R
E
N
I
I
E
K
Y
S
T
E
S
I
L
E
K
W
L
N
L
F
N
S
32
PsiBlast_CBE
50.24
37%
-51
- C6 -
1AY4
1
TYRB_PARDE
B:
[182-229]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
A
N
L
T
L
D
Q
W
A
--------------
E
I
A
S
---
I
L
E
-
K
T
G
A
L
P
---------------------
L
I
D
-
L
-------------------------
A
Y
Q
-----
G
F
G
D
--------
G
L
E
E
D
A
A
G
T
R
L
I
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
48.47
37%
-54
- C6 -
2AY5
1
TYRB_PARDE
B:
[182-229]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
A
N
L
T
L
D
Q
W
A
--------------
E
I
A
S
---
I
L
E
-
K
T
G
A
L
P
---------------------
L
I
D
-
L
-------------------------
A
Y
Q
-----
G
F
G
D
--------
G
L
E
E
D
A
A
G
T
R
L
I
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
52
Fugue
46.93
14%
8
- C3 -
4UX8
-
GFRA1_RAT
C:
[25-343]
--------
D
R
L
D
-------
C
V
K
A
S
D
Q
C
L
K
E
Q
S
C
---
S
T
K
Y
R
T
--------
L
R
Q
C
V
A
G
K
---
E
T
N
F
S
L
T
-----
S
G
--------
L
E
A
K
D
E
C
R
S
-------
A
M
E
A
L
K
Q
K
S
L
Y
N
C
R
C
K
R
G
M
K
----------
K
E
K
N
C
L
R
I
Y
W
S
M
Y
Q
S
K
G
N
----
N
C
L
D
A
A
K
A
C
N
L
D
D
T
C
K
K
-
Y
R
S
A
Y
I
T
P
C
T
T
S
M
S
N
E
V
C
N
----------------
R
R
K
C
H
K
A
----
L
R
Q
F
F
D
K
V
P
A
K
H
S
Y
G
M
LFC
S
C
-----
R
D
I
A
C
T
------
E
R
R
R
Q
T
I
V
P
V
C
S
Y
E
--------------
E
R
E
R
PNC
L
S
L
-
Q
D
S
C
K
T
N
Y
I
C
R
--------------
S
R
L
A
D
F
F
-------------------------
T
N
C
Q
P
E
S
R
S
V
S
N
--------
C
L
K
E
N
Y
A
D
C
L
L
A
Y
S
G
L
--
I
G
T
-
V
----
M
T
P
N
Y
V
D
S
S
S
L
S
V
---------
A
--------------------
P
W
C
D
C
S
N
S
G
-------------
N
D
L
E
D
-----
C
L
K
F
L
N
F
--------------
F
K
D
N
T
C
L
K
N
A
I
Q
A
F
G
N
G
----------------------------------------------------------------------------------
24
PsiBlast_CBE
46.76
37%
-34
- C6 -
2AY6
1
TYRB_PARDE
B:
[182-229]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
A
N
L
T
L
D
Q
W
A
--------------
E
I
A
S
---
I
L
E
-
K
T
G
A
L
P
---------------------
L
I
D
-
L
-------------------------
A
Y
Q
-----
G
F
G
D
--------
G
L
E
E
D
A
A
G
T
R
L
I
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
46.76
37%
-54
- C6 -
1AY4
1
TYRB_PARDE
A:
[182-229]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
A
N
L
T
L
D
Q
W
A
--------------
E
I
A
S
---
I
L
E
-
K
T
G
A
L
P
---------------------
L
I
D
-
L
-------------------------
A
Y
Q
-----
G
F
G
D
--------
G
L
E
E
D
A
A
G
T
R
L
I
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
46.74
37%
-41
- C6 -
2AY4
2
TYRB_PARDE
B:
[182-229]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
A
N
L
T
L
D
Q
W
A
--------------
E
I
A
S
---
I
L
E
-
K
T
G
A
L
P
---------------------
L
I
D
-
L
-------------------------
A
Y
Q
-----
G
F
G
D
--------
G
L
E
E
D
A
A
G
T
R
L
I
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
PsiBlast_CBE
46.62
37%
-47
- C6 -
1AY5
1
TYRB_PARDE
B:
[182-229]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
A
N
L
T
L
D
Q
W
A
--------------
E
I
A
S
---
I
L
E
-
K
T
G
A
L
P
---------------------
L
I
D
-
L
-------------------------
A
Y
Q
-----
G
F
G
D
--------
G
L
E
E
D
A
A
G
T
R
L
I
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
46.57
37%
-33
- C6 -
2AY3
2
TYRB_PARDE
B:
[182-229]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
A
N
L
T
L
D
Q
W
A
--------------
E
I
A
S
---
I
L
E
-
K
T
G
A
L
P
---------------------
L
I
D
-
L
-------------------------
A
Y
Q
-----
G
F
G
D
--------
G
L
E
E
D
A
A
G
T
R
L
I
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
PsiBlast_CBE
46.49
37%
-32
- C6 -
2AY2
2
TYRB_PARDE
B:
[182-229]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
A
N
L
T
L
D
Q
W
A
--------------
E
I
A
S
---
I
L
E
-
K
T
G
A
L
P
---------------------
L
I
D
-
L
-------------------------
A
Y
Q
-----
G
F
G
D
--------
G
L
E
E
D
A
A
G
T
R
L
I
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
46.23
37%
-47
- C6 -
1AY8
1
TYRB_PARDE
A:
[182-229]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
A
N
L
T
L
D
Q
W
A
--------------
E
I
A
S
---
I
L
E
-
K
T
G
A
L
P
---------------------
L
I
D
-
L
-------------------------
A
Y
Q
-----
G
F
G
D
--------
G
L
E
E
D
A
A
G
T
R
L
I
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
PsiBlast_CBE
46.03
37%
-46
- C6 -
1AY8
1
TYRB_PARDE
B:
[182-229]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
A
N
L
T
L
D
Q
W
A
--------------
E
I
A
S
---
I
L
E
-
K
T
G
A
L
P
---------------------
L
I
D
-
L
-------------------------
A
Y
Q
-----
G
F
G
D
--------
G
L
E
E
D
A
A
G
T
R
L
I
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
45.87
10%
-29
- C2 -
3QPR
-
CAPSD_BPHK7
A:
[134-381]
----------------------------------------------------------------------------------------------------------
I
R
D
L
L
A
Q
G
R
T
S
--
S
N
A
--
L
E
Y
V
R
E
E
V
F
T
N
N
A
---------
P
----
E
S
D
I
T
F
-
S
K
Q
T
A
N
V
K
T
I
-
A
H
W
V
Q
A
-
S
R
Q
V
M
D
D
A
P
M
L
Q
--------
S
----
Y
I
N
N
R
L
M
Y
G
--------
L
A
L
K
E
E
G
Q
L
L
N
G
D
---
G
T
GDNLE
G
L
N
K
V
A
T
A
Y
DTS
L
N
A
T
G
D
-
T
R
A
D
I
I
A
--------------
H
A
I
Y
---
Q
V
T
E
S
E
F
S
A
S
G
I
V
L
N
--------------
P
R
D
W
H
N
I
-------------------------
A
L
L
K
D
N
E
G
R
--
Y
--------
I
F
G
G
P
------
Q
A
F
T
S
N
I
M
W
G
-
L
P
V
V
P
T
K
A
--
Q
A
------------------
A
G
T
F
T
V
G
-
G
F
--
D
M
----
A
S
Q
V
W
D
R
M
D
A
T
V
E
V
S
REDR
D
N
F
V
K
N
M
L
-----
T
I
L
C
E
E
R
--------------
L
A
L
A
H
Y
R
P
T
A
I
I
K
G
T
F
-----------------------------------------------------------------------------------
29
PsiBlast_CBE
45.53
37%
-54
- C6 -
2AY1
2
TYRB_PARDE
B:
[182-229]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
A
N
L
T
L
D
Q
W
A
--------------
E
I
A
S
---
I
L
E
-
K
T
G
A
L
P
---------------------
L
I
D
-
L
-------------------------
A
Y
Q
-----
G
F
G
D
--------
G
L
E
E
D
A
A
G
T
R
L
I
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
45.45
37%
-39
- C6 -
2AY9
2
TYRB_PARDE
A:
[182-229]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
A
N
L
T
L
D
Q
W
A
--------------
E
I
A
S
---
I
L
E
-
K
T
G
A
L
P
---------------------
L
I
D
-
L
-------------------------
A
Y
Q
-----
G
F
G
D
--------
G
L
E
E
D
A
A
G
T
R
L
I
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
HHSearch
45.33
17%
-147
* C6 *
4UXD
-
KDGA_PICTO
A:
[70-98]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
F
P
Y
F
T
L
K
E
R
K
--------------
D
F
L
K
---
F
V
R
-
E
N
S
K
K
P
I
M
A
G
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
45.30
37%
-43
- C6 -
1AY5
1
TYRB_PARDE
A:
[182-229]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
A
N
L
T
L
D
Q
W
A
--------------
E
I
A
S
---
I
L
E
-
K
T
G
A
L
P
---------------------
L
I
D
-
L
-------------------------
A
Y
Q
-----
G
F
G
D
--------
G
L
E
E
D
A
A
G
T
R
L
I
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
44.95
37%
-42
- C6 -
2AY4
1
TYRB_PARDE
A:
[182-229]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
A
N
L
T
L
D
Q
W
A
--------------
E
I
A
S
---
I
L
E
-
K
T
G
A
L
P
---------------------
L
I
D
-
L
-------------------------
A
Y
Q
-----
G
F
G
D
--------
G
L
E
E
D
A
A
G
T
R
L
I
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
44.90
37%
-44
- C6 -
2AY3
1
TYRB_PARDE
A:
[182-229]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
A
N
L
T
L
D
Q
W
A
--------------
E
I
A
S
---
I
L
E
-
K
T
G
A
L
P
---------------------
L
I
D
-
L
-------------------------
A
Y
Q
-----
G
F
G
D
--------
G
L
E
E
D
A
A
G
T
R
L
I
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------