@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu21320: (2016-07-03 )
MRKKRVITCVMAASLTLGSLLPAGYATAKEDSKTTPSYEELALHYKMKSEKISSNGKLVEIEYVSGNETHKVQMNGNDHTVKVDGIEQKGLNFEYDENAANRTNYENNNLKSNEFTTQAAKPKKGYHYVGTLSGHTKAAKNALSVTMSLVGIVPGLGWGSKAATILFSYWAKEQIPDAYYKYDLYEKGAMTDSWYQYATVQFFEDKAHKKKMGKPWTSTPAKVDLPNS
Atome Classification :
(13 SA)
----------------------------------------------------------------------------.........10.....---...--------20---.....--------...30------------........40--------........50.......-----------.60........70----------........80.......---------.90-------....--------.-...100.......110------.......120..---------------.....130------.-........140---...----..---------.------.-----150.--.-----.---....-160------------------------.......170...--.---...180-.-------....-------..190.......-----200.......210-........220......-------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------------------------------------------MRK
K
R
V
I
T
C
V
M
A
A
S
L
T
---
L
G
S
--------LL---PAGYA--------TAKED------------SKTTP
S
Y
E
E
L
--------
A
L
H
Y
K
MKSEKISSNG
K
L
-----------
V
E
I
E
Y
VSGN
E
T
H
K
----------
V
Q
MNGND
H
T
V
K
VDGIEQ---------KGL-------
N
F
EY--------D-ENAANRTNYENNNLKS------NEFTTQAAKPKK---------------G
Y
H
Y
V
G
--------T-LSGH
T
K
A
A
K
N
A
---
L
S
V
----
T
M
---------
S
------
L
-----
V
G
IV--P-----G---LGWG-S
K
A
------------------------
A
T
I
L
F
S
Y
W
A
K
EQI--P---
D
A
Y
Y
KY-D-------LYEK-------GAMTDS
W
Y
Q
Y
A
T
-----
V
Q
F
F
E
D
K
A
H
K
K
K--MGKPWTSTP
A
K
VDLPNS-------------------------------------------------------------------------------------------------------------------------
10
Fugue
72.78
23%
9
- C1 -
4F0D
1
PAR16_HUMAN
A:
[2-271]
---------------------------------------------------------------MG
W
A
A
A
R
E
A
A
G
R
D
M
L
A
A
D
L
R
C
S
L
F
A
S
A
L
Q
SYK
R
D
S
--------
V
L
RPF
P
A
S
Y
A
RGDCKD
F
E
A
L
L
A
D
------------
A
S
K
L
P
N
L
K
E
L
L
Q
S
SGDNH
K
R
A
W
D
L
V
S
W
I
L
S
S
--
K
V
-----------
L
T
I
H
S
A
G
K
A
E
F
E
K
----------
I
Q
K
L
T
G
A
P
H
T
P
V
P
A
P
D
----------
F
L
F
-------
E
I
E
Y
----------
F
D
P
A
N
A
K
F
Y
E
T
K
G
E
R
D
------
L
I
Y
A
F
H
G
S
R
L
E
N
---------------
F
H
S
I
I
H
--------
N
G
L
H
C
H
K
T
S
L
F
G
E
G
T
Y
L
T
S
----
D
L
---------
S
------
L
-----
A
L
I
Y
S
P
H
-----
G
---
H
G
W
Q
H
S
L
L
------------------------
G
P
I
L
S
C
V
A
V
C
E
V
I
DH
P
---
D
K
Y
F
V
V
-
T
---------------------
N
N
Q
L
L
R
V
K
Y
-----
L
L
V
Y
S
Q
--------------------------------------------------------------------------------------------------------------------------------------------------
12
Fugue
65.76
16%
41
- C6 -
4D7E
1
?
A:
[1-413]
ME
T
L
L
V
VGAG
P
K
A
L
A
V
A
A
K
S
H
V
L
R
Q
L
GLSAPR
V
I
A
V
E
AHAVGGNWLASGGWTDGRHRLGTSPEKDIGFPYHSTWAR
G
H
N
R
E
I
N
E
A
M
M
A
F
S
W
T
---
S
F
L
--------
V
E
---
H
G
T
Y
A
--------
E
W
I
D
R
------------
G
R
P
S
P
Q
H
H
V
W
--------
A
K
Y
L
Q
W
V
A
R
K
I
D
L
E
L
V
L
-----------
G
K
V
R
T
I
R
--
Q
G
W
S
----------
V
E
V
A
G
A
T
T
E
L
E
A
D
G
L
M
I
---------
T
G
P
-------
G
Q
S
T
--------
K
-
A
L
A
A
H
P
-----
R
V
L
S
I
------
A
E
F
W
D
L
A
G
K
R
K
L
---------------
P
I
S
S
R
A
--------
A
-
V
I
G
G
G
E
T
A
G
S
A
---
L
D
E
L
V
R
H
E
M
---------
L
------
T
-----
I
S
V
I
--
S
-----
P
---
M
A
----------------------------------------------------------------
S
Y
F
E
-------
N
S
L
F
S
D
P
T
K
W
N
A
-----
L
S
I
Q
E
R
R
D
V
I
R
R
--
T
D
R
G
V
F
S
V
R
V
Q
E
S
L
L
G
D
NR
V
H
H
L
Q
G
R
VT
R
I
V
G
Q
G
D
G
V
A
V
T
L
R
N
EMR
A
D
Q
V
H
N
F
DLVVDATGGQPL
W
F
L
D
L
FD
S
E
S
A
D
L
L
E
L
A
V
GGPLT
Q
Q
R
I
E
S
S
IGYDLAVTGLG
A
K
L
Y
L
PNMAALAQGPGFPNLSC
L
G
E
L
S
D
R
V
L
R
7
Fugue
65.08
17%
-20
- C5 -
2A35
-
?
A:
[4-215]
------------------------------------------------------------------------------
T
P
K
R
V
L
L
A
G
A
T
G
L
T
---
G
E
H
--------
L
L
---
D
R
I
L
S
--------
E
P
T
L
A
------------
K
V
I
A
P
A
R
K
A
L
--------
A
E
H
P
R
L
D
N
P
V
G
P
L
A
E
L
L
-----------
P
Q
L
D
----------------------
G
S
I
D
T
A
F
C
C
L
G
------------------------
T
T
--------
I
-
K
E
A
G
S
E
E
A
F
R
A
V
D
F
D
L
------
P
L
A
V
G
K
R
A
L
E
M
G
---------------
A
R
H
Y
L
V
V
S
A
L
GADA
K
-
S
S
I
F
Y
N
R
V
K
G
E
---
L
E
Q
----
A
L
---------
Q
E
QGWP
Q
L
-----
T
I
A
R
--
P
-----
S
---
L
L
F
G
-
P
R
E
------------------------
E
F
R
L
A
E
I
L
A
A
P
I
A
--
G
-------
K
Y
-
H
-------
G
I
E
A
-------
C
D
L
A
R
A
L
W
R
L
A
L
E
E
G
K
G
V
R
F
V
E
S
D
E
L
R
K
L
--
G
K
G
S
--------------------------------------------------------------------------------------------------------------------------------------
13
Fugue
55.30
19%
-18
- C3 -
4M02
2
A:
[36-204]
--------------------------------------------------------------------------------
A
V
T
Q
V
R
Y
V
D
V
T
T
---
G
K
D
--------
I
I
---
P
P
K
T
Y
--------
S
G
N
V
D
------------
Q
V
V
T
I
D
N
Q
Q
S
--------
A
L
T
A
K
------------------------
G
Y
N
Y
T
S
V
D
S
S
Y
A
----------
S
T
Y
N
D
T
N
K
T
V
K
M
T
--------------------------------------
N
A
G
Q
S
V
T
Y
Y
F
T
D
V
K
A
------
P
T
V
T
V
G
N
Q
T
I
E
V
---------------
G
K
T
M
N
P
--------
I
-
V
L
T
T
T
D
N
G
T
G
-----
T
V
----
T
N
---------
T
------
V
-----
T
G
L
P
--
S
-----
G
---
L
S
Y
D
-
S
A
T
------------------------
N
S
I
I
-----------------------------------------
G
T
P
T
K
I
G
Q
S
T
V
T
-----
V
V
S
T
D
Q
A
---------
N
N
K
S
T
T
T
F
T
I
N
V
V
D
T
T------------------------------------------------------------------------------------------------------------------------
9
Fugue
42.33
10%
45
* C6 *
1PV1
-
SFGH_YEAST
A:
[1-299]
----------------------------------------------------------------------------
M
K
V
V
K
E
F
S
V
C
G
G
R
L
I
K
---
L
S
H
N
S
NSTK
T
S
M
N
---
V
N
I
Y
L
--------
P
K
H
Y
Y
------------
A
Q
D
F
P
R
N
K
R
I
--------
P
T
V
F
Y
L
S
G
L
T
C
T
P
D
N
A
S
-----------
E
K
A
F
W
Q
F
Q
A
D
K
Y
G
----------
F
A
I
V
F
P
D
T
S
P
R
G
D
E
V
A
N
DPEGSWDFG
Q
G
A
-------
G
F
Y
L
--------
N
A
T
Q
E
P
Y
A
Q
H
Y
Q
M
Y
D
Y
I
H
------
K
E
L
P
Q
T
L
D
S
H
F
N
---------------
K
L
D
F
L
D
N
V
------
A
-
I
T
G
H
S
M
G
G
Y
G
A
---
I
C
G
----
Y
L
K
G
Y
SGKRYK
S
------
C
-----
S
A
F
A
--
P
IVNPS
N
---
V
P
W
G
-
Q
K
A
------------------------
F
K
G
Y
L
G
E
W
E
A
Y
D
P
--
C
---
L
L
I
K
N
I
-
R
H
V
G
D
D
R
I
L
I
H
V
-------
G
D
S
D
P
F
L
E
E
H
L
K
-----
P
E
L
L
L
E
A
V
K
A
T
S
--
W
Q
D
Y
V
E
I
K
K
V
H
-
G
F
D
H
S
Y
Y
F
V
S
T
F
V
P
E
H
A
E
F
H
A
R
N
L
GLI---------------------------------------------------------------------------------------------------
8
Fugue
42.04
19%
21
* C5 *
1Z0P
-
?
A:
[1-77]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
S
Y
-
E
K
E
------------------------
F
L
K
D
F
E
D
W
V
K
T
Q
I
--
Q
---
V
N
Q
L
A
M
-
A
-------
T
S
Q
E
V
AD
E
R
A
K
D
A
F
I
R
Y
E
S
K
L
D
A
-----
Y
E
F
L
L
G
K
F
D
N
Y
K
--
N
G
K
A
F
H
D
I
P
D
E
-------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
41.19
27%
10
- C7 -
1UYQ
1
BGLA_PAEPO
A:
[362-439]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
G
K
V
-----------
Q
D
D
R
R
I
S
Y
M
Q
Q
H
L
----------
V
Q
V
----
H
R
A
I
H
D
G
L
H
V
---------
K
G
Y
M
A
WSLLD
N
F
E
W
--------
A
-
E
G
Y
N
M
R
F
G
-----
M
I
H
------
V
D
F
R
T
Q
V
R
T
P
K
Q
---------------
S
Y
Y
W
Y
R
--------
N
-
V
V
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
Fugue
40.00
20%
-40
* C7 *
1IQ5
-
?
B:
[4-27]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
P
R
L
D
T
-----
L
I
L
V
K
A
M
G
H
R
K
R
--
F
G
N
P
F
R
------------------------------------------------------------------------------------------------------------------------------------
11
Fugue
38.01
11%
48
- C4 -
4AG4
4
DDR1_HUMAN
A:
[5-344]
---------------------------------------------------------------------KCRYALG
M
Q
D
R
T
I
P
D
S
D
I
S
A
S
S
S
---
W
S
D
--------
S
T
---
A
A
R
H
S
--------
R
L
E
S
S
DGDG
A
W
C
P
AGSV
F
P
K
E
E
E
Y
L
Q
V
--------
D
L
Q
R
L
H
L
V
A
L
V
G
T
Q
G
R
H
AGGLGKEFSR
S
Y
R
L
R
Y
S
R
D
G
R
R
W
M
G
W
K
D
RWGQEV
I
S
G
N
E
D
P
E
G
V
V
L
K
D
L
G
P
---------
P
M
V
-------
A
R
L
V
R
F
Y
P
R
A
DR
V
-
M
S
V
C
L
R
V
E
L
Y
G
C
L
W
R
D
------
G
L
L
S
Y
T
A
P
V
G
Q
T
M
YLSEAVYLNDSTYD
G
H
T
V
G
G
--------
L
-
Q
Y
G
G
L
G
Q
L
A
D
G
---
V
V
G
----
L
D
---------
D
------
F
RKSQE
L
R
V
W
--
P
-----
G
YD
Y
V
G
W
S
-
N
H
S
FSSG
Y
-------------------
V
E
M
E
F
E
F
D
R
L
R
A
F
--
Q
---
A
M
Q
V
H
C
N
N
-------
M
H
T
L
-------
G
A
R
L
---
P
G
G
V
E
-----
C
R
F
R
R
G
P
A
M
A
W
E
--
G
E
P
M
R
H
N
L
G
G
N
L
G
D
P
R
A
R
A
V
S
V
P
LGGRVAR
F
L
Q
C
R
F
L
F
AGP
W
L
L
F
S
E
I
S
F
I
S
D
A
A-----------------------------------------------------------------------------------
2
PsiBlast_PDB
34.52
24%
-8
- C2 -
4IOV
-
?
A:
[546-622]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
N
T
T
T
S
A
N
N
L
L
F
T
------
S
E
E
E
I
A
A
T
N
P
R
D
---------------
T
D
M
F
G
Q
--------
I
-
A
D
N
N
Q
N
A
T
T
A
P
---
I
T
G
----
N
V
---------
T
------
A
-----
M
G
V
L
--
P
-----
G
---
M
V
W
Q
-
N
R
D
------------------------
I
Y
Y
Q
G
P
I
W
A
K
--
I
--
P
---
H
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
Fugue
31.60
16%
101
- C5 -
4TKO
2
?
B:
[3-349]
--------------HRIEYAITNAVFVKADELSYLSFRVSGKVIEVYKDLGDYVKRGEALAKLDPTYYELEKRTLE
K
K
M
S
A
L
L
E
K
K
K
A
L
E
I
K
---
I
Q
K
--------
L
E
---
K
G
L
H
I
--------
S
L
S
A
K
------------
K
L
K
V
E
S
L
K
K
K
--------
R
E
A
L
R
E
K
L
L
Q
V
E
E
K
I
K
L
-----------
V
K
L
D
W
E
R
Y
K
S
L
F
Q
----------
K
G
L
I
P
R
R
K
F
E
E
V
D
T
N
L
K
---------
V
L
L
H------
E
R
E
Y
--------
L
-
E
K
S
I
Q
E
I
N
T
E
I
K
R
A
K
K
GIENAR
N
E
F
K
T
I
E
E
L
K
K
E
---------------
L
S
S
L
E
E
--------
E
-
I
K
S
L
K
E
R
I
K
T
A
---
E
Q
K
----
I
K
---------
D
------
T
-----
V
L
I
A
--
P
-----
F
---
D
G
V
V
-
A
K
R
FISRGDVVRAGQPAFALVNPESFY
V
E
V
L
L
E
E
T
K
L
K
G
V
--
K
VGN
K
A
Y
V
R
L
-
D
-------
A
Y
P
D
-------
I
L
F
E
G
V
V
E
E
I
S
P
-----
V
Q
R
I
P
V
K
I
K
I
T
K
GD
L
S
L
L
R
V
G
M
G
G
E
V
E
I
R
R
T
-------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
21.81
31%
66
- C7 -
3WFI
-
?
A:
[252-289]
----------------------------------------------------------------------------------------------------------------------------------------------------
E
T
I
--------
G
L
H
Y
P
S
M
Y
Q
D
L
I
K
N
H
R
L
-----------
T
E
I
D
Y
I
N
G
A
I
S
R
K
----------
G
K
K
Y
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
21.33
31%
77
- C7 -
3WFJ
1
?
A:
[252-289]
----------------------------------------------------------------------------------------------------------------------------------------------------
E
T
I
--------
G
L
H
Y
P
S
M
Y
Q
D
L
I
K
N
H
R
L
-----------
T
E
I
D
Y
I
N
G
A
I
S
R
K
----------
G
K
K
Y
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------