@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu22320: (2016-07-04 )
MSDQFNSREARRKANSKSSPSPKKGKKRKKGGLFKKTLFTLLILFVLGVVGGAVTFAVMVSDAPSLDESKLKTPYSSTIYDKNGKEIAEVGAEKRTYVSIDEIPDVVKEAFIATEDARFYEHHGIDPVRIGGALVANFKDGFGAEGGSTITQQVVKNSLLSHQKTLKRKVQEVWLSIQLERNYSKDEILEMYLNRIYFSPRAYGIGKAAEEFFGVTDLSKLTVEQAATLAGMPQSPTAYNPVKNPDKAEKRRNIVLSLMKKQGFISDSQYNKAKKVAVKDEGVVSQKEYEKASTNKYSAFVEEVMKEIDEKSDVDPSADGLKIYTTLDTKAQDKLDELMDGDTVGFTEGMQGGVTLLDTKNGEVRAIGAGRNQPVGGFNYATQTKAQPGSTIKPILDYGPVIENKKWSTYEQIDDSAYTYSNGKPIRDWDRKYLGPISMRYALAQSRNIPALKAFQAVGKDTAVDFANGLGLGLTKDNVTEAYSIGGFGGNDGVSPLTMAGAYSAFGNNGTYNEPHFVKSIEFNDGTKLDLTPKSKSAMSDYTAFMITDMLKTAVKTGTGQLAQVPGVEVAGKTGTTNFDDNEVKRYNIASGGARDSWFVGYTPQYTAAVWTGMGENEAGKKSLSAEEQKVAKRIFAQLIADVDDGSGSFEKPDSVVEATVEKGSNPAKLAGPNTPSDKKLTEYFVKGTAPSTVSKTYEKEEKEETAKLSGLNVKYDKDNQSLTLSWNYDGDATFAVKQSVDGGSYSEIQNSSAKEAVISGVQPGSVYKFEVTAVSDDGKSTASTSYEVPKAEDDEDKKDQQQTDDEKQDDEKTQDDTQTDDSQKDDGQTDQDQTDDSTNDQDKKQDNTNTNPSDNNNQDQSNDNDNDNSNNQDTSDGDSNSGKNDSTGSDTNKNKTDTSNKTQTNSSSIEKTN
Atome Classification :
(22 SA)
.........10........20........30........40........50........60........70........80........90.-........100.......110.......120.......130.......140.......150.......160.......170......---.180.......190.......200--.........210...------...-------.220.......230.......240.......250.......260.......270-.--.......280.-.....----.290....---...300......----.310--..------.---....-----.320.......330.......340-....-----------------------------------------------------------------------------------------------------------...---------------------------------------------------------------------------------------------------350.......360.......370-...-.---...380.......390.......400.....-..-410....--...420----.-..---.....430.--......440.......450......----.460.......470...-..-.--.--480.......490--.......500.......510......-.520.......530-------------.-.--------......540.......550....-.-..560.-.-......570......--.580.....-..590.......600.......610....-...620-......-.--.630.......640....--...-650.....-..660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.......910..
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MSDQF
N
S
R
E
A
R
RKANSKSSPSPKKGKKRKKGG
L
F
K
K
T
L
F
T
L
L
I
L
F
V
L
G
VVGG
A
V
T
F
A
V
M
VSDAPSL
D
E
S
KLKTPYSSTIYDKN
G
K
E
I
A
E
V-G-AEK
R
T
Y
V
S
I
D
E
I
P
D
V
V
K
E
A
F
IATEDA
R
F
Y
E
HHGI
D
P
V
RIG
G
A
L
V
A
NFKDGFGAEG
G
S
T
I
T
Q
Q
V
V
K
N
S
L
L
S
H
Q
K
T
L
K
R
K
V
Q
E
V
W
L
S
I
Q
---
L
ERNY
S
K
D
E
I
L
E
M
Y
L
N
R
IYFSP----RAYGI
G
K
A
A
E
E
F
FGV------
T
D
L
-------
S
K
L
T
V
E
Q
A
A
T
LAGMPQSPTAYNPVKN
P
D
K
A
E
K
R
R
N
I
V
L
S
L
M
K
KQGFISDSQYN--K--A
K
K
V
A
VKDEGV-V
S
Q
K
E
----
Y
E
KASTN
K
---
Y
S
A
F
V
E
E
V
M
K
E
I----DEK---SD------V---DPSA-----D
G
L
K
I
Y
T
TLD
T
K
A
Q
D
K
L
D
E
LMDGD-TVGF-----------------------------------------------------------------------------------------------------------TEG---------------------------------------------------------------------------------------------------MQG
G
V
T
L
L
DTKNG
E
V
R
A
IGAGRN-QPV-G---GFNYATQTKAQPGSTIK
P
I
LDYGPVIENKKW-S
T
-
Y
E
QIDDS--AYTY-S----N-GK---PI
R
D
W
D
R
K
Y--L
G
P
I
S
M
R
Y
A
L
AQSRN
I
P
A
L
K
A
F
Q
A
V----GKDT
A
V
DFANGLGLGLT-KD-N--V--T
E
A
Y
S
IGGFGGND--GVS
P
L
T
MAGAYSAFGNNGTYNEP
H
F
V
-
K
S
I
EFNDG
T
K
L
D
-L-------------T-P--------KSKSA
M
S
D
Y
T
A
F
M
I
T
D
M
L
K
T
A
V
K
-T-GTG-
Q
L
-A-QVP
G
V
E
V
AGKTGTTN--FDDNE
V
K
R
Y
-
N
IASGGARD
S
W
F
VGYTPQ
Y
T
A
A
V
WTGMGE-NEAGK--KSL
S
A
E
-
E
--
Q
K
V
A
K
R
I
F
A
Q
L
I
A
DVDDG--SGS-FEK
P
D
S
V
V
-
E
A
T
V
E
KGSNPAKLAGPNTPS
D
K
K
L
T
E
Y
F
VKGTAP
S
T
V
S
K
T
Y
E
K
E
E
K
E
E
T
AKLSG
L
N
V
K
YDKDN
Q
S
L
T
L
S
W
NYDG
D
A
T
F
A
V
K
QSVDGG
S
Y
S
E
I
QNS
S
A
K
E
A
V
I
SGVQPG
S
V
Y
K
F
E
V
T
A
VSDDGKSTASTSYEVPKAEDDEDKKDQQQTDDEKQDDEKTQDDTQTDDSQKDDGQTDQDQTDDSTNDQDKKQDNTNTNPSDNNNQDQSNDNDNDNSNNQDTSDGDSNSGKNDSTGSDTNKNKTDTSNKTQTNSSSIEKTN
2
PsiBlast_PDB
76.07
37%
69
- C2 -
2OLV
1
?
A:
[9-611]
--------------------------------------------------------------------
A
K
L
Q
D
P
I
P
A
K
I
Y
D
K
N
G
E
L
V
K
T
L
D
N
-
G
Q
R
H
E
H
V
N
L
K
D
V
P
K
S
M
K
D
A
V
L
A
T
E
D
N
R
F
Y
E
H
G
A
L
D
Y
K
R
L
F
G
A
I
G
K
---------
G
A
S
T
L
T
Q
Q
V
V
K
D
A
F
L
S
Q
H
K
S
I
G
R
K
A
Q
E
A
Y
L
S
Y
R
---
L
E
Q
E
Y
S
K
D
D
I
F
Q
V
Y
L
N
K
I
Y
Y
S
D
----
G
V
T
G
I
K
A
A
A
K
Y
Y
F
N
-------
K
D
L
-------
K
D
L
N
L
A
E
E
A
Y
L
A
G
L
P
Q
V
P
N
N
Y
N
I
Y
D
H
P
K
A
A
E
D
R
K
N
T
V
L
Y
L
M
H
Y
H
K
R
I
T
D
K
Q
W
E
--
D
--
A
K
K
I
D
L
K
A
N
L
V
N
R
T
P
E
E
----
R
Q
N
I
D
T
N
Q
DSE
Y
N
S
Y
V
N
F
V
K
S
E
L
M
---
N
N
K
---
A
F
------
K
---
D
E
N
L
G
N
V
L
Q
S
G
I
K
I
Y
T
N
M
D
K
D
V
Q
K
T
L
Q
N
D
V
D
N
G
-
S
F
Y
K
-----------------------------------------------------------------------------------------------------------
N
K
D
---------------------------------------------------------------------------------------------------
Q
Q
V
G
A
T
I
L
D
S
K
T
G
G
L
V
A
I
S
G
G
R
D
F
K
D
V
-
V
---
N
R
N
Q
A
T
D
P
H
P
T
-
G
S
S
L
K
P
F
L
A
Y
G
P
A
I
E
N
M
K
W
-
A
T
-
N
H
A
I
Q
D
E
--
S
S
Y
Q
-
V
----
D
-
G
S
---
T
F
R
N
Y
D
T
K
S
--
H
G
T
V
S
I
Y
D
A
L
R
Q
S
F
N
I
P
A
L
K
A
W
Q
S
V
K
Q
NA
G
N
D
A
P
K
K
F
A
A
K
L
G
L
N
Y
E
-
G
D
----
I
--
G
P
S
E
V
L
G
G
S
A
S
E
----
F
S
P
T
Q
L
A
S
A
F
A
A
I
A
N
G
G
T
Y
N
N
A
H
S
I
-
Q
K
V
V
T
R
D
G
E
T
I
E
-
Y
-------------
D
-
H
--------
T
S
H
K
A
M
S
D
Y
T
A
Y
M
L
A
E
M
L
K
G
T
F
K
-
P
Y
G
S
A
-
Y
G
-
H
-
G
V
S
G
V
N
M
G
A
K
T
G
T
G
T
--
Y
G
A
E
T
Y
S
Q
Y
-
N
L
P
D
N
A
A
K
D
V
W
I
N
G
F
T
P
Q
Y
T
M
S
V
W
M
G
F
S
K
V
K
Q
Y
G
E
--
N
S
F
V
G
H
S
Q
--
Q
E
Y
P
Q
F
L
Y
E
N
V
M
S
K
I
S
S
R
--
D
G
E
D
F
K
R
P
S
S
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
75.60
37%
71
- C2 -
3DWK
10
?
C:
[3-602]
-----------------------------------------------------------------------
Q
D
P
I
P
A
K
I
Y
D
K
N
G
E
L
V
K
T
L
D
N
-
G
Q
R
H
E
H
V
N
L
K
D
V
P
K
S
M
K
D
A
V
L
A
T
E
D
N
R
F
Y
E
H
G
A
L
D
Y
K
R
L
F
G
A
I
G
K
N
L
T
G
G
F
G
S
E
G
A
S
T
L
T
Q
Q
V
V
K
D
A
F
L
S
Q
H
K
S
I
G
R
K
A
Q
E
A
Y
L
S
Y
R
---
L
E
Q
E
Y
S
K
D
D
I
F
Q
V
Y
L
N
K
I
Y
Y
S
D
----
G
V
T
G
I
K
A
A
A
K
Y
Y
F
N
-------
K
D
L
-------
K
D
L
N
L
A
E
E
A
Y
L
A
G
L
P
Q
V
P
N
N
Y
N
I
Y
D
H
P
K
A
A
E
D
R
K
N
T
V
L
Y
L
M
H
Y
H
K
R
I
T
D
K
Q
W
E
--
D
--
A
K
K
I
D
L
K
A
N
L
V
N
R
T
P
E
E
----
R
Q
N
I
D
T
N
Q
DSE
Y
N
S
Y
V
N
F
V
K
S
E
L
M
---
N
N
K
---
A
F
------
K
---
D
E
N
L
G
N
V
L
Q
S
G
I
K
I
Y
T
N
M
D
K
D
V
Q
K
T
L
Q
N
D
V
D
N
G
-
S
F
Y
K
-----------------------------------------------------------------------------------------------------------
N
K
D
---------------------------------------------------------------------------------------------------
Q
Q
V
G
A
T
I
L
D
S
K
T
G
G
L
V
A
I
S
G
G
R
D
F
K
D
V
-
V
---
N
R
N
Q
A
T
D
P
H
P
T
-
G
S
S
L
K
P
F
L
A
Y
G
P
A
I
E
N
M
K
W
-
A
T
-
N
H
A
I
Q
D
E
--
S
S
Y
Q
-
V
----
D
-
G
S
---
T
F
R
N
Y
D
T
K
S
--
H
G
T
V
S
I
Y
D
A
L
R
Q
S
F
N
I
P
A
L
K
A
W
Q
S
V
K
Q
N
A
G
N
D
A
P
K
K
F
A
A
K
L
G
L
N
Y
E
-
G
D
----
I
--
G
P
S
E
V
L
G
G
S
A
S
E
----
F
S
P
T
Q
L
A
S
A
F
A
A
I
A
N
G
G
T
Y
N
N
A
H
S
I
-
Q
K
V
V
T
R
D
G
E
T
I
E
-
Y
-------------
D
-
H
--------
T
S
H
K
A
M
S
D
Y
T
A
Y
M
L
A
E
M
L
K
G
T
F
K
P
Y
-
G
S
A
-
Y
G
-
H
-
G
V
S
G
V
N
M
G
A
K
T
G
T
G
T
--
Y
G
A
E
T
Y
S
Q
Y
-
N
L
P
D
N
A
A
K
D
V
W
I
N
G
F
T
P
Q
Y
T
M
S
V
W
M
G
F
S
K
V
K
Q
Y
G
E
--
N
S
F
V
G
H
S
Q
--
Q
E
Y
P
Q
F
L
Y
E
N
V
M
S
K
I
S
S
R
--
D
G
E
D
F
K
R
P
S
S
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
75.51
37%
67
- C2 -
2OLU
1
?
A:
[10-611]
---------------------------------------------------------------------
K
L
Q
D
P
I
P
A
K
I
Y
D
K
N
G
E
L
V
K
T
L
D
N
-
G
Q
R
H
E
H
V
N
L
K
D
V
P
K
S
M
K
D
A
V
L
A
T
E
D
N
R
F
Y
E
H
G
A
L
D
Y
-------------
G
F
G
S
E
G
A
S
T
L
T
Q
Q
V
V
K
D
A
F
L
S
----
I
G
R
K
A
Q
E
A
Y
L
S
Y
R
---
L
E
Q
E
Y
S
K
D
D
I
F
Q
V
Y
L
N
K
I
Y
Y
S
D
----
G
V
T
G
I
K
A
A
A
K
Y
Y
F
N
-------
K
D
L
-------
K
D
L
N
L
A
E
E
A
Y
L
A
G
L
P
Q
V
P
N
N
Y
N
I
Y
D
H
P
K
A
A
E
D
R
K
N
T
V
L
Y
L
M
H
Y
H
K
R
I
T
D
K
Q
W
E
--
D
--
A
K
K
I
D
L
K
A
N
L
V
N
R
T
P
E
E
----
R
Q
N
I
D
T
N
Q
DSE
Y
N
S
Y
V
N
F
V
K
S
E
L
M
---
N
N
K
---
A
F
------
K
---
D
E
N
L
G
N
V
L
Q
S
G
I
K
I
Y
T
N
M
D
K
D
V
Q
K
T
L
Q
N
D
V
D
N
G
-
S
F
Y
K
-----------------------------------------------------------------------------------------------------------
N
K
D
---------------------------------------------------------------------------------------------------
Q
Q
V
G
A
T
I
L
D
S
K
T
G
G
L
V
A
I
S
G
G
R
D
F
K
D
V
-
V
---
N
R
N
Q
A
T
D
P
H
P
T
-
G
S
S
L
K
P
F
L
A
Y
G
P
A
I
E
N
M
K
W
-
A
T
-
N
H
A
I
Q
D
E
--
S
S
Y
Q
-
V
----
D
-
G
S
---
T
F
R
N
Y
D
T
K
S
--
H
G
T
V
S
I
Y
D
A
L
R
Q
S
F
N
I
P
A
L
K
A
W
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L
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L
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-
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----
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----
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-------------
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--------
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--
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--
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K
I
S
S
R
--
D
G
E
D
F
K
R
P
S
S
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
74.91
38%
70
* C2 *
2OLV
1
?
A:
[9-621]
--------------------------------------------------------------------
A
K
L
Q
D
P
I
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A
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---
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----
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N
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---
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A
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L
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---
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-----
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-
S
F
Y
K
-----------------------------------------------------------------------------------------------------------
N
K
D
---------------------------------------------------------------------------------------------------
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N
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L
G
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N
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E
--
G
-
D
--
I
--
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L
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G
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A
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----
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F
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Q
L
A
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A
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A
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A
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G
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N
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A
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S
I
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K
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D
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E
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I
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-
Y
-------------
D
-
H
--------
T
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H
K
A
M
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D
Y
T
A
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M
L
A
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M
L
K
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T
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Y
-
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--
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L
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M
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K
R
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S
S
V
S
G
S
I
P
S
I
N
V
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
74.75
37%
71
- C2 -
3DWK
4
?
B:
[4-602]
------------------------------------------------------------------------
D
P
I
P
A
K
I
Y
D
K
N
G
E
L
V
K
T
L
D--
G
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---
L
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----
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-------
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L
-------
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--
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DSE
Y
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---
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N
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---
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------
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---
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-----------------------------------------------------------------------------------------------------------
N
K
D
---------------------------------------------------------------------------------------------------
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Q
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----
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--
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----
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--------
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--
D
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E
D
F
K
R
P
S
S
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
73.85
37%
68
- C2 -
3DWK
12
?
D:
[6-602]
--------------------------------------------------------------------------
I
P
A
K
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D
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N
G
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R
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-----------------------------------------------------------------------------------------------------------
N
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D
---------------------------------------------------------------------------------------------------
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-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
63.36
28%
38
- C2 -
3UDI
1
?
A:
[19-727]
-------------------------------------------------------------------------------------------------------------------------------
K
P
L
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G
-
R
S
---
D
L
G
G
K
T
G
T
T
N
-----------------
D
A
K
D
A
W
F
A
G
F
N
G
K
L
V
T
V
T
W
V
G
F
D
Q
-
P
------
T
T
L
G
R
R
-
E
YG
G
I
A
A
L
P
I
W
I
N
F
M
G
Q
A
L
Q
G
--
T
P
A
-
A
W
V
R
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
62.21
29%
32
- C2 -
3FWL
1
PBPB_ECOLI
A:
[152-695]
--------------------------------------------------------------------------------------
I
S
S
P
-
N
-
G
E
Q
R
L
F
V
P
R
S
G
F
P
D
L
L
V
D
T
L
L
A
T
E
D
R
H
F
Y
E
H
D
G
I
S
L
Y
S
I
-------------------
L
T
Q
Q
L
V
K
N
L
F
L
S
S
E
R
S
Y
W
R
K
A
N
E
A
Y
M
A
L
I
---
M
D
A
R
Y
S
K
D
R
I
L
E
L
Y
M
N
E
V
Y
L
G
Q
SGD
N
E
I
R
G
F
P
L
A
S
L
Y
Y
F
G
-------
R
P
V
-------
E
E
L
S
L
D
Q
Q
A
L
L
V
G
M
V
K
G
A
S
I
Y
N
P
W
R
N
P
K
L
A
L
E
R
R
N
L
V
L
R
L
L
Q
Q
Q
Q
I
I
D
Q
E
L
Y
D
--
M
LS
A
R
P
---------
V
I
S
P
Q
----------------
P
A
F
M
Q
L
V
R
Q
E
L
----
Q
A
K
L--
G
D
------
K
---
V
K
D
L
-----
S
G
V
K
I
F
T
T
F
D
S
V
A
Q
D
A
A
E
K
A
A
V
E
G
-
I
P
A
L
-----------------------------------------------------------------------------------------------------------
K
K
Q
R
KLSD----------------------------------------------------------------------------------------------
L
E
T
A
I
V
V
V
D
R
F
S
G
E
V
R
A
M
V
G
G
S
E
-
P
Q
F
-
A
---
G
Y
N
R
A
M
Q
A
R
R
S
I
G
S
L
A
K
P
A
T
Y
L
T
A
L
S
Q
P
K
I
Y
-
R
L
-
N
T
W
I
A
D
A
P
I
A
L
R
Q
-
P
----
N
-
G
Q
V
W
S
P
Q
N
D
-
D
R
R
Y
SE
S
G
R
V
M
L
V
D
A
L
T
R
S
M
N
V
P
T
V
N
L
G
M
A
L
----
G
L
P
A
V
T
E
--
T
W
I
K
L
G
V
P
-
K
D
-
Q
--
L
HP
V
P
A
M
L
L
G
A
L
------
N
L
T
P
I
E
V
A
Q
A
F
Q
T
I
A
S
G
G
N
R
A
P
L
S
A
L
-
R
S
V
I
A
E
D
G
K
V
L
Y
-
Q
-------------
S
F
P
--------
Q
A
E
R
A
V
P
A
Q
A
A
Y
L
T
L
W
T
M
Q
Q
V
V
Q
-
R
-
G
T
G
R
Q
L
G
A
-
K
Y
P
N
L
H
L
A
G
K
T
G
T
T
N
-----
N
N
V
------------
D
T
W
F
A
G
I
D
G
S
T
V
T
I
T
W
V
G
R
D
N
-
N
Q
P
T
K
--
L
Y
G
A
S
G
-
A
--
M
S
I
Y
Q
R
Y
L
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
HHSearch
61.81
34%
35
- C2 -
3ZG9
5
?
B:
[9-464]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
D
E
I
M
E
M
Y
L
N
R
S
Y
F
G
N
----
G
E
W
G
V
E
N
A
S
L
K
Y
F
G
K
-------
S
A
-------
A
D
L
N
I
P
E
A
A
T
I
A
G
L
L
Q
A
P
S
A
Y
D
P
Y
Q
H
I
D
K
A
T
N
R
R
N
M
V
L
N
A
M
V
E
T
G
T
I
S
K
A
E
G
D
--
K
--
Y
K
A
T
K
I
V
L
N
D
Q
-
S
K
--
D
----
P
---
L
A
N
K
---
Y
P
W
Y
V
D
A
V
I
N
E
A
----
V
N
E
A
DI
T
Q
------
D
---
E
I
M
Q
-----
K
G
Y
K
I
Y
T
E
L
D
Q
N
Y
Q
T
S
L
E
N
V
Y
N
N
D
-
G
L
F
P
SNAND------------------------------------------------------------------------------------------------------
G
T
L
---------------------------------------------------------------------------------------------------
V
Q
S
G
A
V
L
M
D
P
A
T
G
G
I
R
A
L
V
G
G
R
G
-
E
H
V
F
R
---
G
F
N
R
A
T
Q
M
K
A
Q
P
G
S
T
M
K
P
L
A
V
Y
T
P
A
L
Q
S
G
-
Y
-
D
V
-
D
S
M
L
K
D
E
--
K
I
T
Y
-
K
----
G
-
N
Y
---
T
P
T
N
V
G
G
V
Y
--
S
G
E
V
P
M
Y
K
A
V
A
N
S
I
N
A
P
A
V
W
L
L
D
Q
I
----
G
I
D
K
G
V
K
S
V
E
K
F
G
I
T
V
P
-
E
K
-
D
--
R
--
T
L
G
L
A
L
G
G
M
S
K
----
G
A
S
P
V
E
M
A
T
A
Y
A
T
F
A
N
N
G
A
K
P
E
S
H
I
I
-
T
K
I
V
D
P
S
G
N
T
V
Y
E
N
-------------
V
-
P
--------
K
T
K
Q
I
I
S
E
T
V
S
N
E
M
T
S
M
L
L
D
V
I
N
-
T
-
G
T
G
-
Q
S
-
A
-
A
V
S
G
H
E
M
A
G
K
T
G
S
T
Q
--
V
P
F
D
D
--------
T
S
G
T
K
D
Q
W
F
V
G
Y
T
P
N
L
V
G
A
V
W
M
G
Y
D
K
-
T
D
K
E
---
H
Y
L
T
T
T
-
S
--
S
A
G
V
S
S
L
A
H
Y
V
M
N
S
G
L
Q
Y
Q-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
61.00
36%
36
- C2 -
3ZG9
5
?
B:
[9-431]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
D
E
I
M
E
M
Y
L
N
R
S
Y
F
G
N
----
G
E
W
G
V
E
N
A
S
L
K
Y
F
G
-------
K
S
A
-------
A
D
L
N
I
P
E
A
A
T
I
A
G
L
L
Q
A
P
S
A
Y
D
P
Y
Q
H
I
D
K
A
T
N
R
R
N
M
V
L
N
A
M
V
E
T
G
T
I
S
K
A
E
G
D
K
Y
K
--
A
T
K
I
V
L
N
D
Q
S
------------
K
D
P
L
A
N
K
---
Y
P
W
Y
V
D
A
V
I
N
E
A
----
V
N
E
---
A
D
------
I
T
Q
D
E
I
M
Q
-----
K
G
Y
K
I
Y
T
E
L
D
Q
N
Y
Q
T
S
L
E
N
V
Y
N
N
D
-
G
L
F
P
-----------------------------------------------------------------------------------------------------------
S
N
A
NDGTL----------------------------------------------------------------------------------------------
V
Q
S
G
A
V
L
M
D
P
A
T
G
G
I
R
A
L
V
G
G
R
G
-
E
H
V
F
R
---
G
F
N
R
A
T
Q
M
K
A
Q
P
G
S
T
M
K
P
L
A
V
Y
T
P
A
L
Q
S
-
G
Y
-
D
V
-
D
S
M
L
K
D
E
--
K
I
T
Y
-
K
----
G
-
N
Y
---
T
P
T
N
V
G
G
V
Y
--
S
G
E
V
P
M
Y
K
A
V
A
N
S
I
N
A
P
A
V
W
L
L
D
Q
I
----
G
I
D
K
G
V
K
S
V
E
K
F
G
I
T
V
P
-
E
K
-
D
--
R
--
T
L
G
L
A
L
G
G
M
--
S
K
--
G
A
S
P
V
E
M
A
T
A
Y
A
T
F
A
N
N
G
A
K
P
E
S
H
I
I
T
K
I
V
D
P
S
G
N
T
V
Y
E
-
N
-------------
V
-
P
--------
K
T
K
Q
I
I
S
E
T
V
S
N
E
M
T
S
M
L
L
D
V
I
N
-
T
-
G
T
G
-
Q
S
-
A
-
A
V
S
G
H
E
M
A
G
K
T
G
S
T
Q
V
P
F
D
D
----------
T
S
G
T
K
D
Q
W
F
V
G
Y
T
P
N
L
V
G
A
V
W
M
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
59.45
34%
34
- C2 -
3ZG7
2
?
B:
[8-431]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
D
E
I
M
E
M
Y
L
N
R
S
Y
F
G
N
----
G
E
W
G
V
E
N
A
S
L
K
Y
F
G
K
------
S
-
A
-------
A
D
L
N
I
P
E
A
A
T
I
A
G
L
L
Q
A
P
S
A
Y
D
P
Y
Q
H
I
D
K
A
T
N
R
R
N
M
V
L
N
A
M
V
E
T
G
T
I
S
K
A
E
G
D
K
Y
K
--
A
T
K
I
V
L
N
D
Q
S
------------
K
D
P
L
A
N
K
---
Y
P
W
Y
V
D
A
V
I
N
E
A
----
V
N
E
---
A
D
------
I
T
Q
D
E
I
M
Q
-----
K
G
Y
K
I
Y
T
E
L
D
Q
N
Y
Q
T
S
L
E
N
V
Y
N
N
D
-
G
L
F
P
-----------------------------------------------------------------------------------------------------------
S
N
A
NDGTL----------------------------------------------------------------------------------------------
V
Q
S
G
A
V
L
M
D
P
A
T
G
G
I
R
A
L
V
G
G
R
G
-
E
H
V
F
R
---
G
F
N
R
A
T
Q
M
K
A
Q
P
G
S
T
M
K
P
L
A
V
Y
T
P
A
L
Q
S
-
G
Y
-
D
V
-
D
S
M
L
K
D
E
--
K
I
T
Y
-
K
----
G
-
N
Y
---
T
P
T
N
V
G
G
V
Y
--
S
G
E
V
P
M
Y
K
A
V
A
N
S
I
N
A
P
A
V
W
L
L
D
Q
I
----
G
I
D
K
G
V
K
S
V
E
K
F
G
I
T
V
P
-
E
K
-
D
--
R
--
T
L
G
L
A
L
G
G
M
--
S
K
--
G
A
S
P
V
E
M
A
T
A
Y
A
T
F
A
N
N
G
A
K
P
E
S
H
I
I
T
K
I
V
D
P
S
G
N
T
V
Y
E
-
N
-------------
V
-
P
--------
K
T
K
Q
I
I
S
E
T
V
S
N
E
M
T
S
M
L
L
D
V
I
N
-
T
-
G
T
G
-
Q
S
-
A
-
A
V
S
G
H
E
M
A
G
K
T
G
S
T
Q
V
P
F
D
D
----------
T
S
G
T
K
D
Q
W
F
V
G
Y
T
P
N
L
V
G
A
V
W
M
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
58.73
36%
37
- C2 -
3ZGA
4
?
B:
[7-431]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
S
K
D
E
I
M
E
M
Y
L
N
R
S
Y
F
G
N
----
G
E
W
G
V
E
N
A
S
L
K
Y
F
G
-------
K
S
A
-------
A
D
L
N
I
P
E
A
A
T
I
A
G
L
L
Q
A
P
S
A
Y
D
P
Y
Q
H
I
D
K
A
T
N
R
R
N
M
V
L
N
A
M
V
E
T
G
T
I
S
K
A
E
G
D
K
Y
K
--
A
T
K
I
V
L
N
D
Q
S
------------
K
D
P
L
A
N
K
---
Y
P
W
Y
V
D
A
V
I
N
E
A
----
V
N
E
---
A
D
------
I
T
Q
D
E
I
M
Q
-----
K
G
Y
K
I
Y
T
E
L
D
Q
N
Y
Q
T
S
L
E
N
V
Y
N
N
D
-
G
L
F
P
-----------------------------------------------------------------------------------------------------------
S
N
A
NDGTL----------------------------------------------------------------------------------------------
V
Q
S
G
A
V
L
M
D
P
A
T
G
G
I
R
A
L
V
G
G
R
G
-
E
H
V
F
R
---
G
F
N
R
A
T
Q
M
K
A
Q
P
G
S
T
M
K
P
L
A
V
Y
T
P
A
L
Q
S
-
G
Y
-
D
V
-
D
S
M
L
K
D
E
--
K
I
T
Y
-
K
----
G
-
N
Y
---
T
P
T
N
V
G
G
V
Y
--
S
G
E
V
P
M
Y
K
A
V
A
N
S
I
N
A
P
A
V
W
L
L
D
Q
I
----
G
I
D
K
G
V
K
S
V
E
K
F
G
I
T
V
P
-
E
K
-
D
--
R
--
T
L
G
L
A
L
G
G
M
--
S
K
--
G
A
S
P
V
E
M
A
T
A
Y
A
T
F
A
N
N
G
A
K
P
E
S
H
I
I
T
K
I
V
D
P
S
G
N
T
V
Y
E
-
N
-------------
V
-
P
--------
K
T
K
Q
I
I
S
E
T
V
S
N
E
M
T
S
M
L
L
D
V
I
N
-
T
-
G
T
G
-
Q
S
-
A
-
A
V
S
G
H
E
M
A
G
K
T
G
S
T
Q
V
P
F
D
D
----------
T
S
G
T
K
D
Q
W
F
V
G
Y
T
P
N
L
V
G
A
V
W
M
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
57.67
36%
37
- C2 -
3ZG8
4
?
B:
[7-431]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
S
K
D
E
I
M
E
M
Y
L
N
R
S
Y
F
G
N
----
G
E
W
G
V
E
N
A
S
L
K
Y
F
G
-------
K
S
A
-------
A
D
L
N
I
P
E
A
A
T
I
A
G
L
L
Q
A
P
S
A
Y
D
P
Y
Q
H
I
D
K
A
T
N
R
R
N
M
V
L
N
A
M
V
E
T
G
T
I
S
K
A
E
G
D
K
Y
K
--
A
T
K
I
V
L
N
D
Q
S
------------
K
D
P
L
A
N
K
---
Y
P
W
Y
V
D
A
V
I
N
E
A
----
V
N
E
---
A
D
------
I
T
Q
D
E
I
M
Q
-----
K
G
Y
K
I
Y
T
E
L
D
Q
N
Y
Q
T
S
L
E
N
V
Y
N
N
D
-
G
L
F
P
-----------------------------------------------------------------------------------------------------------
S
N
A
NDGTL----------------------------------------------------------------------------------------------
V
Q
S
G
A
V
L
M
D
P
A
T
G
G
I
R
A
L
V
G
G
R
G
-
E
H
V
F
R
---
G
F
N
R
A
T
Q
M
K
A
Q
P
G
S
T
M
K
P
L
A
V
Y
T
P
A
L
Q
S
-
G
Y
-
D
V
-
D
S
M
L
K
D
E
--
K
I
T
Y
-
K
----
G
-
N
Y
---
T
P
T
N
V
G
G
V
Y
--
S
G
E
V
P
M
Y
K
A
V
A
N
S
I
N
A
P
A
V
W
L
L
D
Q
I
----
G
I
D
K
G
V
K
S
V
E
K
F
G
I
T
V
P
-
E
K
-
D
--
R
--
T
L
G
L
A
L
G
G
M
--
S
K
--
G
A
S
P
V
E
M
A
T
A
Y
A
T
F
A
N
N
G
A
K
P
E
S
H
I
I
T
K
I
V
D
P
S
G
N
T
V
Y
E
-
N
-------------
V
-
P
--------
K
T
K
Q
I
I
S
E
T
V
S
N
E
M
T
S
M
L
L
D
V
I
N
-
T
-
G
T
G
-
Q
S
-
A
-
A
V
S
G
H
E
M
A
G
K
T
G
S
T
Q
V
P
F
D
D
----------
T
S
G
T
K
D
Q
W
F
V
G
Y
T
P
N
L
V
G
A
V
W
M
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
HHSearch
56.25
30%
14
- C2 -
4OON
1
PBPA_PSEAE
A:
[20-765]
---------------------------------------------------------------------------
P
L
K
V
Y
S
E
D
G
K
L
I
S
E
F
-
G
-
E
M
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
---
P
E
L
N
---
A
P
Y
I
A
E
M
A
R
A
E
M
----
V
G
R
---
Y
G
------
S
---
E
A
Y
T
-----
E
G
Y
K
V
I
T
T
V
R
S
D
L
Q
N
A
A
S
Q
S
V
R
D
G
-
L
I
D
Y
D
Q
R
H
GYRGPE
T
R
L
P
GQT
R
D
A
W
L
K
H
L
G
Q
Q
R
S
I
GG
L
E
P
A
I
V
TQVEKS
G
I
M
V
M
T
RDG
K
E
E
A
V
T
WDSMKWARPFLSNNSMGPMPRQPADVAQAG
D
Q
I
R
V
Q
R
Q
EDGTL
R
F
V
Q
I
P
A
---------------------------------------------------------------------------------------------------
A
Q
S
A
L
I
S
L
D
P
K
D
G
A
I
R
S
L
V
G
G
F
S
-
F
E
Q
-
S
---
N
Y
N
R
A
I
Q
A
K
R
Q
P
G
S
S
F
K
P
F
I
-
Y
S
A
A
L
D
N
-
G
F
-
T
A
-
A
S
L
V
N
D
A
--
P
I
V
F
-
V
D
E
Y
L--------------
T
F
--
L
G
P
I
P
L
R
E
A
L
Y
K
S
R
N
M
V
S
I
R
V
L
Q
G
L
----
G
I
E
R
A
I
S
Y
I
T
K
F
G
F
Q
R
D
-
E
L
-
P
--
R
--
N
F
S
L
A
L
G
T
A
------
T
V
T
P
M
E
I
A
G
A
W
S
V
F
A
N
G
G
Y
K
V
N
P
Y
V
I
-
E
R
I
E
S
R
D
G
Q
V
L
Y
Q
A
-------------
N
-
P
PRVPVE
P
T
P
A
E
R
I
I
D
A
R
T
A
Y
I
M
T
S
M
L
Q
D
V
I
K
-
R
-
G
T
G
-
R
R
-
A
L
A
L
K
R
T
D
L
A
G
K
T
G
T
T
N
--
D
S
---------------
K
D
G
W
F
S
G
Y
N
S
D
Y
V
T
S
V
W
V
G
F
D
Q
-
P
E
T
L
----
G
R
R
E
Y
-
G
--
G
T
V
A
L
P
I
W
I
R
Y
M
G
F
A
L
K
D
KP
M
H
T
-
M
A
E
P
P
G
I
V
-
S
L
R
I
D
P
V
T
--
G
R
S
A
A
P
G
T
P
G
--
A
Y
F
E
M
F
K
N
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
HHSearch
54.71
33%
59
- C2 -
2V2F
3
?
F:
[5-383]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
P
A
Y
M
D
N
Y
L
K
E
V
INQV
E
Q
E
---
T
G
------
Y
---
N
L
L
T
-----
T
G
M
D
V
Y
T
N
V
D
Q
E
A
Q
K
H
L
W
D
I
Y
N
S
D
-
Q
Y
V
S
YP---------------------------------------------------------------------------------------------------------
D
D
D
---------------------------------------------------------------------------------------------------
L
Q
V
A
S
T
V
V
D
V
S
N
G
K
V
I
A
Q
L
G
A
R
H
------SF-
G
T
N
Q
A
V
E
T
N
R
D
W
G
S
A
M
K
P
I
T
D
Y
A
P
A
I
E
Y
G
V
Y
-
D
S
T
A
T
M
V
N
D
I
--
P
Y
N
Y
-
P
----
G
T
S
T
---
P
V
Y
N
W
D
R
A
Y
--
F
G
N
I
T
L
Q
Y
A
L
Q
Q
S
R
N
V
T
A
V
E
T
L
N
K
V
----
G
L
D
R
A
K
T
F
L
N
G
L
G
I
D
Y
P
S
M
H
Y
A
NA
I
SS
N
T
T
E
S
N
K
Q
Y
------
G
A
S
S
E
K
M
A
A
A
Y
A
A
F
A
N
G
G
I
Y
H
K
P
M
Y
I
-
N
K
V
V
F
S
D
G
S
K
K
E
-
F
-------------
S
-
D
--------
V
G
T
R
A
M
K
E
T
T
A
Y
M
M
T
E
M
M
K
T
V
L
A
-
Y
-
G
T
G
-
R
G
-
A
-
Y
L
P
W
L
A
Q
A
G
K
T
G
T
S
N
--
Y
T
D
-----------
Y
V
A
P
D
E
M
F
V
G
Y
T
R
K
Y
S
M
A
V
W
T
G
Y
S
N
-
R
L
T
P
---
I
--
V
G
D
-
G
--
F
L
V
A
A
K
V
Y
R
S
M
I
T
Y
L
S
E
G
S-
P
E
D
-
W
N
I
P
E
G
L
Y
-
R
N
G
E
F
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
54.68
34%
53
- C2 -
2ZC6
6
?
D:
[12-366]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
L
K
E
V
I
N
Q
V
----
E
E
E
---
T
G
------
Y
---
N
L
L
T
-----
T
G
M
D
V
Y
T
N
V
D
Q
E
A
Q
K
H
L
W
D
I
Y
N
T
D
E
Y
V
A
Y
-----------------------------------------------------------------------------------------------------------
P
D
D
E--------------------------------------------------------------------------------------------------
L
Q
V
A
S
T
I
V
D
V
S
N
G
K
V
I
A
Q
L
G
A
R
H
-
Q
S
S
-
N
VSF
G
I
N
Q
A
V
E
T
N
R
D
W
G
S
T
M
K
P
I
T
D
Y
A
P
A
L
E
Y
G
V
Y
D
S
T
-
A
T
I
V
H
D
E
--
P
Y
N
Y
P
G
----
T
-
N
T
---
P
V
Y
N
W
D
R
G
Y
--
F
G
N
I
T
L
Q
Y
A
L
Q
Q
S
R
N
V
P
A
V
E
T
L
N
K
V
----
G
L
N
R
A
K
T
F
L
N
G
L
G
I
D
Y
P
-
S
I
-
H
--
Y
--
S
N
A
I
S
S
N
T
T
E
S
D
K
KY
G
A
S
S
E
K
M
A
A
A
Y
A
A
F
A
N
G
G
T
Y
Y
K
P
M
Y
I
-
H
K
V
V
F
S
D
G
S
E
K
E
-
F
-------------
S
-
N
--------
V
G
T
R
A
M
K
E
T
T
A
Y
M
M
T
D
M
M
K
T
V
L
S
-
Y
-
G
T
G
-
Q
N
-
A
-
Y
L
A
W
L
P
Q
A
G
K
T
G
T
S
N
--
Y
T
D
E
E
I
E
N
H
I
K
T
S
Q
F
V
A
P
D
E
L
F
A
G
Y
T
R
K
Y
S
M
A
V
W
T
G
Y
S
N
-
R
---
L
--
T
P
L
V
G
N
-
G
--
L
T
V
A
A
K
V
Y
R
S
M
M
T
Y
L
S
E
G
--
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
54.20
34%
50
- C2 -
2ZC6
6
?
B:
[12-366]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
L
K
E
V
I
N
Q
V
----
E
E
E
---
T
G
------
Y
---
N
L
L
T
-----
T
G
M
D
V
Y
T
N
V
D
Q
E
A
Q
K
H
L
W
D
I
Y
N
T
D
E
Y
V
A
Y
-----------------------------------------------------------------------------------------------------------
P
D
D
E--------------------------------------------------------------------------------------------------
L
Q
V
A
S
T
I
V
D
V
S
N
G
K
V
I
A
Q
L
G
A
R
H
-
Q
S
S
-
N
VSF
G
I
N
Q
A
V
E
T
N
R
D
W
G
S
T
M
K
P
I
T
D
Y
A
P
A
L
E
Y
G
V
Y
D
S
T
-
A
T
I
V
H
D
E
--
P
Y
N
Y
P
G
----
T
-
N
T
---
P
V
Y
N
W
D
R
G
Y
--
F
G
N
I
T
L
Q
Y
A
L
Q
Q
S
R
N
V
P
A
V
E
T
L
N
K
V
----
G
L
N
R
A
K
T
F
L
N
G
L
G
I
D
Y
P
-
S
I
-
H
--
Y
--
S
N
A
I
S
S
N
T
T
E
S
D
K
KY
G
A
S
S
E
K
M
A
A
A
Y
A
A
F
A
N
G
G
T
Y
Y
K
P
M
Y
I
-
H
K
V
V
F
S
D
G
S
E
K
E
-
F
-------------
S
-
N
--------
V
G
T
R
A
M
K
E
T
T
A
Y
M
M
T
D
M
M
K
T
V
L
S
-
Y
-
G
T
G
-
Q
N
-
A
-
Y
L
A
W
L
P
Q
A
G
K
T
G
T
S
N
--
Y
T
D
E
E
I
E
N
H
I
K
T
S
Q
F
V
A
P
D
E
L
F
A
G
Y
T
R
K
Y
S
M
A
V
W
T
G
Y
S
N
-
R
---
L
--
T
P
L
V
G
N
-
G
--
L
T
V
A
A
K
V
Y
R
S
M
M
T
Y
L
S
E
G
--
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
53.31
34%
53
- C2 -
2ZC5
6
?
D:
[12-366]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
L
K
E
V
I
N
Q
V
----
E
E
E
---
T
G
------
Y
---
N
L
L
T
-----
T
G
M
D
V
Y
T
N
V
D
Q
E
A
Q
K
H
L
W
D
I
Y
N
T
D
E
Y
V
A
Y
-----------------------------------------------------------------------------------------------------------
P
D
D
E--------------------------------------------------------------------------------------------------
L
Q
V
A
S
T
I
V
D
V
S
N
G
K
V
I
A
Q
L
G
A
R
H
-
Q
S
S
-
N
VSF
G
I
N
Q
A
V
E
T
N
R
D
W
G
S
T
M
K
P
I
T
D
Y
A
P
A
L
E
Y
G
V
Y
D
S
T
-
A
T
I
V
H
D
E
--
P
Y
N
Y
P
G
----
T
-
N
T
---
P
V
Y
N
W
D
R
G
Y
--
F
G
N
I
T
L
Q
Y
A
L
Q
Q
S
R
N
V
P
A
V
E
T
L
N
K
V
----
G
L
N
R
A
K
T
F
L
N
G
L
G
I
D
Y
P
-
S
I
-
H
--
Y
--
S
N
A
I
S
S
N
T
T
E
S
D
K
KY
G
A
S
S
E
K
M
A
A
A
Y
A
A
F
A
N
G
G
T
Y
Y
K
P
M
Y
I
-
H
K
V
V
F
S
D
G
S
E
K
E
-
F
-------------
S
-
N
--------
V
G
T
R
A
M
K
E
T
T
A
Y
M
M
T
D
M
M
K
T
V
L
S
-
Y
-
G
T
G
-
Q
N
-
A
-
Y
L
A
W
L
P
Q
A
G
K
T
G
T
S
N
--
Y
T
D
E
E
I
E
N
H
I
K
T
S
Q
F
V
A
P
D
E
L
F
A
G
Y
T
R
K
Y
S
M
A
V
W
T
G
Y
S
N
-
R
---
L
--
T
P
L
V
G
N
-
G
--
L
T
V
A
A
K
V
Y
R
S
M
M
T
Y
L
S
E
G
--
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
52.83
34%
49
- C2 -
2C6W
8
?
B:
[9-363]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
L
K
E
V
I
N
Q
V
----
E
E
E
---
T
G
------
Y
---
N
L
L
T
-----
T
G
M
D
V
Y
T
N
V
D
Q
E
A
Q
K
H
L
W
D
I
Y
N
T
D
E
Y
V
A
Y
-----------------------------------------------------------------------------------------------------------
P
D
D
E--------------------------------------------------------------------------------------------------
L
Q
V
A
S
T
I
V
D
V
S
N
G
K
V
I
A
Q
L
G
A
R
H
-
Q
S
S
-
N
VSF
G
I
N
Q
A
V
E
T
N
R
D
W
G
S
T
M
K
P
I
T
D
Y
A
P
A
L
E
Y
G
V
Y
D
S
T
-
A
T
I
V
H
D
E
--
P
Y
N
Y
P
G
----
T
-
N
T
---
P
V
Y
N
W
D
R
G
Y
--
F
G
N
I
T
L
Q
Y
A
L
Q
Q
S
R
N
V
P
A
V
E
T
L
N
K
V
----
G
L
N
R
A
K
T
F
L
N
G
L
G
I
D
Y
P
-
S
I
-
H
--
Y
--
S
N
A
I
S
S
N
T
T
E
S
D
K
KY
G
A
S
S
E
K
M
A
A
A
Y
A
A
F
A
N
G
G
T
Y
Y
K
P
M
Y
I
-
H
K
V
V
F
S
D
G
S
E
K
E
-
F
-------------
S
-
N
--------
V
G
T
R
A
M
K
E
T
T
A
Y
M
M
T
D
M
M
K
T
V
L
T
-
Y
-
G
T
G
-
R
N
-
A
-
Y
L
A
W
L
P
Q
A
G
K
T
G
T
S
N
--
Y
T
D
E
E
I
E
N
H
I
K
T
S
Q
F
V
A
P
D
E
L
F
A
G
Y
T
R
K
Y
S
M
A
V
W
T
G
Y
S
N
-
R
---
L
--
T
P
L
V
G
N
-
G
--
L
T
V
A
A
K
V
Y
R
S
M
M
T
Y
L
S
E
G
--
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
52.66
46%
-84
- C2 -
3NB6
-
PBPA_AQUAE
A:
[61-240]
----------------------------------------------------------------------------------------------
Q
K
R
F
Y
V
S
I
D
K
I
P
E
H
V
I
N
A
F
V
A
T
E
D
R
N
F
W
H
H
F
G
I
D
P
V
A
I
V
R
A
A
I
V
N
Y
R
A
G
R
I
A
Q
G
G
S
T
I
T
Q
Q
L
A
K
N
L
F
L
T
R
E
R
T
L
E
R
K
I
K
E
A
L
L
A
I
K
---
I
E
R
T
F
D
K
K
K
I
M
E
L
Y
L
N
Q
I
Y
L
G
S
----
G
A
Y
G
V
E
A
A
A
Q
V
Y
F
G
-------
K
H
V
-------
W
E
L
S
L
D
E
A
A
L
L
A
A
L
P
K
A
P
A
K
Y
N
P
F
Y
H
P
E
R
A
L
Q
R
R
N
L
V
L
K
R
M
L
E
E
G
Y
I
T
P
E
Q
Y
E
--
E
--
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
HHSearch
43.42
40%
-22
- C2 -
3VMT
3
MGT_STAAM
A:
[72-261]
----------------------------------------------------------------------------------------------
N
K
S
S
F
V
S
A
D
N
M
P
E
Y
V
K
G
A
F
I
S
M
E
D
E
R
F
Y
N
H
H
G
F
D
L
K
G
T
T
R
A
L
F
S
T
--------
G
G
S
T
I
T
Q
Q
V
V
K
N
Y
F
Y
D
N
D
R
S
F
T
R
K
V
K
E
L
F
V
A
H
R
---
V
E
K
Q
Y
N
K
N
E
I
L
S
F
Y
L
N
N
I
Y
F
G
D
----
N
Q
Y
T
L
E
G
A
A
N
H
Y
F
G
T
-------
T
V
NKNSTTM
S
H
I
T
V
L
Q
S
A
I
L
A
S
K
V
N
A
P
S
V
Y
N
I
N
N
M
S
E
N
F
T
Q
R
V
S
T
N
L
E
K
M
K
Q
Q
N
Y
I
N
E
T
Q
Y
Q
--
Q
--
A
M
S
Q
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
40.58
40%
-18
- C2 -
3VMT
3
MGT_STAAM
A:
[73-257]
-----------------------------------------------------------------------------------------------
K
S
S
F
V
S
A
D
N
M
P
E
Y
V
K
G
A
F
I
S
M
E
D
E
R
F
Y
N
H
H
G
F
D
L
K
G
T
T
R
A
L
F
S
T
--------
G
G
S
T
I
T
Q
Q
V
V
K
N
Y
F
Y
D
N
D
R
S
F
T
R
K
V
K
E
L
F
V
A
H
R
---
V
E
K
Q
Y
N
K
N
E
I
L
S
F
Y
L
N
N
I
Y
F
G
D
----
N
Q
Y
T
L
E
G
A
A
N
H
Y
F
G
T
TVNKNS
T
T
M
-------
S
H
I
T
V
L
Q
S
A
I
L
A
S
K
V
N
A
P
S
V
Y
N
I
N
N
M
S
E
N
F
T
Q
R
V
S
T
N
L
E
K
M
K
Q
Q
N
Y
I
N
E
T
Q
Y
Q
--
Q
--
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------