@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu24750: (2016-07-09 )
MPSLEKAVVLEFINLLAVAILILLTGFFVAVEFSIVKVRRSKIDQLVAKGKKGAKAAKHVITHLDEYLSACQLGITVAALGLGWLGEPTVQTLLRPLFHKAGLNESLTHLLSLVIAFLVVTYLNVVIGELAPKSFAIQKAESITLLFAKPLIWFYKIMFPFIWLLNHSARLITGVFGLKPASEHELAYTEEELRVLLAESYKSGEIRKSELKYMNNIFTFDKRMAKEIMVPRNEMVSLSLDEDSISNLQETVKQTKYTRYPVVREDKDNVIGVINMKEVLFSMLTKDFSIKKHQIEPFVQPVIHVIETIPIYKLLLKMQKERTHMAILIDEYGGTSGLVTVEDIIEEIVGEIRDEFDADEVPHIRELGKDHYLLNAKLLISDVNSLLGTDLSEAEVDTLGGWFLTQNIDAEPESAIEYDGYSFKVKDINSHHILFIEVKKAE
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260...-.-.-..270.......280.........290......-.300.......310.......320.......330-------........340.......350.......360.......370.......380.......390.......400....--..-.410.......420.......430.......440
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MP
S
L
E
K
A
V
V
L
E
F
I
N
L
L
A
V
A
I
L
I
L
L
T
G
F
F
V
A
V
E
F
S
I
V
K
V
R
R
S
K
I
D
Q
L
V
A
KGKK
G
A
K
A
A
K
H
V
I
T
H
L
D
E
Y
L
S
A
C
Q
L
G
I
T
V
A
A
L
GLGWLG
E
P
T
V
Q
T
L
L
R
P
L
F
H
KAGL
N
E
S
L
T
H
L
L
S
L
V
I
A
F
L
V
V
T
Y
L
N
V
V
I
G
ELAPKS
F
A
I
Q
KA
E
S
I
T
L
L
FA
K
P
L
I
W
F
Y
K
I
M
F
P
F
I
W
L
LNH
S
A
R
L
I
T
G
VFGLKPASEHELAY
T
E
E
E
L
R
V
L
L
A
E
SYKSGE
I
R
K
S
E
L
K
Y
M
N
N
I
F
T
F
D
K
R
M
A
K
E
IMVPRN
E
M
V
S
L
SLD
E
D
S
I
S
N
L
Q
E
T
V
K
QTKYTRYPVVRE-D-K-D
N
V
I
G
V
I
N
M
K
E
V
L
--
F
S
M
L
TKDFSIKKHQI
E
P
F
-
V
Q
P
V
I
H
V
I
E
TI
P
I
Y
K
L
L
L
K
M
Q
KER
T
H
M
A
I
L
I
DE--------YGGTSG
L
V
T
V
E
D
I
I
E
E
I
V
G
E
I
R
D
EFDADE
V
P
H
I
R
E
LGKD
H
Y
L
L
N
A
K
L
L
I
S
D
V
N
S
L
LGTDLSEA
E
V
D
T
LG
G
W
F
L
TQ--NI-DAEPES
A
I
EYD
G
Y
S
F
K
V
K
DINSH
H
I
L
F
I
E
V
KKAE
25
HHSearch
80.09
31%
-94
* C1 *
4HG0
1
CORC_ECOLI
A:
[51-282]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
D
T
R
D
M
L
E
G
V
M
D
I
A
D
Q
R
V
R
D
I
M
I
P
R
S
Q
M
I
T
L
K
R
N
-
Q
T
L
D
E
C
L
D
V
I
I
E
S
A
H
S
R
F
P
V
I
S
E
-
D
-
K
-
D
H
I
E
G
I
L
M
A
K
D
L
L
--
P
F
M
R
S
D
---
A
E
A
F
S
M
D
K
V
-
L
R
Q
A
V
V
V
P
E
S
K
R
V
D
R
M
L
K
E
F
R
S
Q
R
Y
H
M
A
I
V
I
D
E
--------
F
G
G
V
S
G
L
V
T
I
E
D
I
L
E
L
I
V
G
E
I
E
D
E
Y
D
E
E
D
D
I
D
F
R
Q
L
S
R
H
T
W
T
V
R
A
L
A
S
I
E
D
F
N
E
A
F
G
T
H
F
S
D
E
E
V
D
T
I
G
G
L
V
M
Q
A
--
F
G
H
L
P
A
R
G
E
T
I
D
I
D
G
Y
Q
F
K
V
A
M
A
D
S
R
R
I
I
Q
V
H
V
K
I
P
-
2
PsiBlast_PDB
72.27
30%
-16
- C1 -
4HG0
1
CORC_ECOLI
A:
[51-280]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
D
T
R
D
M
L
E
G
V
M
D
I
A
D
Q
R
V
R
D
I
M
I
P
R
S
Q
M
I
T
L
K
R
N
Q
-
T
L
D
E
C
L
D
V
I
I
E
S
A
H
S
R
F
P
V
I
S
E
-
D
-
K
-
D
H
I
E
G
I
L
M
A
K
D
L
L
PF
M
R
S
D
A
E
A
F
S
M
D
K
-----
V
-
L
R
Q
A
V
V
V
P
E
S
K
R
V
D
R
M
L
K
E
F
R
S
Q
R
Y
H
M
A
I
V
I
D
E
--------
F
G
G
V
S
G
L
V
T
I
E
D
I
L
E
L
I
V
G
E
I
E
D
E
Y
D
E
E
D
D
I
D
F
R
Q
L
S
R
H
T
W
T
V
R
A
L
A
S
I
E
D
F
N
E
A
F
G
T
H
F
S
D
E
E
V
D
T
I
G
G
L
V
M
Q
A
F
G
H
L
-
P
A
R
G
E
T
-
I
D
I
D
G
Y
Q
F
K
V
A
M
A
D
S
R
R
I
I
Q
V
H
V
K
---
29
HHSearch
69.36
40%
-150
- C1 -
3LV9
1
?
A:
[18-147]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
F
E
E
K
K
I
R
E
I
M
V
P
R
T
D
M
V
C
I
Y
E
S
-
D
S
E
E
K
I
L
A
I
L
K
E
E
G
V
T
R
Y
P
V
C
R
K
-
N
-
K
-
D
D
I
L
G
F
V
H
I
R
D
L
Y
--
N
Q
K
I
N
E
----
N
K
I
E
L
E
E
I
-
L
R
D
I
I
Y
I
S
E
N
L
T
I
D
K
A
L
E
R
I
R
K
E
K
L
Q
L
A
I
V
V
D
E
--------
Y
G
G
T
S
G
V
V
T
I
E
D
I
L
E
E
I
V
G
E
I
---------------------------------------------------------------------------------------------
1
PsiBlast_PDB
68.59
37%
-146
- C1 -
3LV9
1
?
A:
[18-147]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
F
E
E
K
K
I
R
E
I
M
V
P
R
T
D
M
V
C
I
-
Y
E
S
D
S
E
E
K
I
L
A
I
L
K
E
E
G
V
T
R
Y
P
V
C
R
K
-
N
-
K
-
D
D
I
L
G
F
V
H
I
R
D
L
Y
--
N
Q
K
I
N
E
N
----
K
I
E
L
E
E
I
-
L
R
D
I
I
Y
I
S
E
N
L
T
I
D
K
A
L
E
R
I
R
K
E
K
L
Q
L
A
I
V
V
D
E
--------
Y
G
G
T
S
G
V
V
T
I
E
D
I
L
E
E
I
V
G
E
I
---------------------------------------------------------------------------------------------
27
HHSearch
67.63
34%
-164
- C1 -
3OI8
4
?
A:
[2-156]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
A
S
A
E
D
V
L
N
L
L
R
Q
A
H
E
Q
E
V
F
D
A
D
T
L
L
R
L
E
K
V
L
D
F
S
D
L
E
V
R
D
A
M
I
T
R
S
R
M
N
V
L
K
E
N
-
D
S
I
E
R
I
T
A
Y
V
I
D
T
A
H
S
R
F
P
V
I
G
E
-
D
-
K
-
D
E
V
L
G
I
L
H
A
K
D
L
L
--
K
Y
M
F
N
P
----
E
Q
F
H
L
K
S
I
-
L
R
P
A
V
F
V
P
E
G
K
S
L
T
A
L
L
K
E
F
R
E
Q
R
N
H
M
A
I
V
I
D
E
--------
Y
G
G
T
S
G
L
V
T
F
E
D
I
I
E
---------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
66.38
35%
-185
- C1 -
3JTF
4
?
A:
[4-128]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
T
V
A
D
I
M
V
P
R
S
R
M
D
L
L
D
I
S
Q
-
P
L
P
Q
L
L
A
T
I
I
E
T
A
H
S
R
F
P
V
Y
E
D
-
D
-
R
-
D
N
I
I
G
I
L
L
A
K
D
L
L
--
R
Y
M
L
E
P
A
L
D
I
R
S
-----
L
-
V
R
P
A
V
F
I
P
E
V
K
R
L
N
V
L
L
R
E
F
R
A
S
R
N
H
L
A
I
V
I
D
E
---------
G
G
I
S
G
L
V
T
M
E
D
V
L
E
Q
I
V
G
D
I
---------------------------------------------------------------------------------------------
5
PsiBlast_PDB
66.31
31%
-157
- C1 -
3OI8
4
?
A:
[4-156]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
A
E
D
V
L
N
L
L
R
Q
A
H
E
Q
E
V
F
D
A
D
T
L
L
R
L
E
K
V
L
D
F
S
D
L
E
V
R
D
A
M
I
T
R
S
R
M
N
V
L
K
-
E
N
D
S
I
E
R
I
T
A
Y
V
I
D
T
A
H
S
R
F
P
V
I
G
E
-
D
-
K
-
D
E
V
L
G
I
L
H
A
K
D
------
L
L
K
Y
M
F
N
P
E
Q
F
H
L
K
S
I
-
L
R
P
A
V
F
V
P
E
G
K
S
L
T
A
L
L
K
E
F
R
E
Q
R
N
H
M
A
I
V
I
D
E
--------
Y
G
G
T
S
G
L
V
T
F
E
D
I
I
E
---------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
64.90
35%
-150
- C1 -
3LFR
2
?
A:
[6-125]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
D
I
M
V
P
R
S
Q
M
I
S
I
K
A
T
Q
-
T
P
R
E
F
L
P
A
V
I
D
A
A
H
S
R
Y
P
V
I
G
E
-
S
-
H
-
D
D
V
L
G
V
L
L
A
K
D
L
L
--
P
L
I
L
K
A
D
G
D
--
S
D
D
V
K
K
L
-
L
R
P
A
T
F
V
P
E
S
K
R
L
N
V
L
L
R
E
F
R
A
N
H
N
H
M
A
I
V
I
D
E
--------
Y
G
G
V
A
G
L
V
T
I
E
D
V
L
E
Q
I
-------------------------------------------------------------------------------------------------
48
Fugue
63.65
32%
-168
- C1 -
3HF7
1
?
A:
[1-127]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
S
V
N
D
I
M
V
P
R
N
E
I
V
G
I
D
I
N
-
D
D
W
K
S
I
V
R
Q
L
T
H
S
P
H
G
R
I
V
L
Y
R
D
-
S
-
L
-
D
D
A
I
S
M
L
R
V
R
E
A
Y
--
R
L
M
T
E
K
K
-
E
F
T
K
E
I
M
L
R
A
-
A
D
E
I
Y
F
V
P
E
G
T
P
L
S
T
Q
L
V
K
F
Q
R
N
K
K
K
V
G
L
V
V
D
E
--------
Y
G
D
I
Q
G
L
V
T
V
E
D
I
L
E
E
I
V
G
-----------------------------------------------------------------------------------------------
6
PsiBlast_PDB
62.81
28%
-165
- C1 -
3LHH
1
?
A:
[43-165]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
S
S
L
M
V
P
R
S
D
I
V
F
L
D
L
N
L
P
L
D
A
N
L
R
-
T
V
M
Q
S
P
H
S
R
F
P
V
C
R
N
-
N
-
V
-
D
D
M
V
G
I
I
S
A
K
Q
------
L
L
S
E
S
I
A
G
E
R
L
E
L
V
D
L
-
V
K
N
C
N
F
V
P
N
S
L
S
G
M
E
L
L
E
H
F
R
T
T
G
S
Q
M
V
F
V
V
D
E
--------
Y
G
D
L
K
G
L
V
T
L
Q
D
M
M
D
A
L
T
G
E
----------------------------------------------------------------------------------------------
9
PsiBlast_PDB
61.67
32%
-178
- C1 -
3HF7
1
?
A:
[6-127]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
M
V
P
R
N
E
I
V
G
I
D
I
N
D
D
W
K
S
I
V
R
Q
-
L
T
H
S
P
H
G
R
I
V
L
Y
R
D
-
S
-
L
-
D
D
A
I
S
M
L
R
V
R
E
A
---
Y
R
L
M
T
E
K
K
E
F
T
K
E
I
M
L
R
A
-
A
D
E
I
Y
F
V
P
E
G
T
P
L
S
T
Q
L
V
K
F
Q
R
N
K
K
K
V
G
L
V
V
D
E
--------
Y
G
D
I
Q
G
L
V
T
V
E
D
I
L
E
E
I
V
G
-----------------------------------------------------------------------------------------------
45
HHSearch
61.66
34%
-162
- C1 -
3NQR
1
CORC_SALTY
A:
[3-124]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
R
V
R
D
I
M
I
P
R
S
Q
M
I
T
L
K
R
N
-
Q
T
L
D
E
C
L
D
V
I
I
E
S
A
H
S
R
F
P
V
I
S
E
-
D
-
K
-
D
H
I
E
G
I
L
M
A
K
D
L
L
--
P
F
M
R
S
D
---
A
E
A
F
S
M
D
K
V
-
L
R
T
A
V
V
V
P
E
S
K
R
V
D
R
M
L
K
E
F
R
S
Q
R
Y
H
M
A
I
V
I
D
E
--------
F
G
G
V
S
G
L
V
T
I
E
D
I
L
E
L
I
-------------------------------------------------------------------------------------------------
32
HHSearch
61.57
25%
-125
- C1 -
3OCM
7
?
A:
[18-166]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
F
G
V
E
E
R
N
M
V
S
G
V
L
T
L
A
E
R
S
I
R
S
I
M
T
P
R
T
D
V
S
W
V
N
I
D
-
D
D
A
A
T
I
R
Q
Q
L
T
A
A
P
H
S
F
F
P
V
C
R
G
-
S
-
L
-
D
E
V
V
G
I
G
R
A
K
D
L
V
--
A
D
L
I
T
E
------
G
R
V
R
R
N
R
L
R
D
P
I
I
V
H
E
S
I
G
I
L
R
L
M
D
T
L
K
R
S
R
G
Q
L
V
L
V
A
D
E
--------
F
G
A
I
E
G
L
V
T
P
I
D
V
F
E
A
I
A
G
E
F
P
D
E
D
E
L
P
--------------------------------------------------------------------------------------
11
PsiBlast_PDB
60.99
32%
-207
- C1 -
3I8N
1
?
A:
[26-130]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
N
E
F
L
D
K
H
K
D
T
P
F
S
R
P
L
V
Y
S
E
-
Q
-
K
-
D
N
I
I
G
F
V
H
R
L
E
-
L
--
F
K
--
M
Q
Q
S
G
S
G
Q
K
Q
L
G
A
V
-
M
R
P
I
Q
V
V
L
N
N
T
A
L
P
K
V
F
D
Q
M
M
T
H
R
L
Q
L
A
L
V
V
D
E
--------
Y
G
T
V
L
G
L
V
T
L
E
D
I
F
E
H
L
V
G
E
----------------------------------------------------------------------------------------------
8
PsiBlast_PDB
60.38
27%
-137
- C1 -
3OCM
7
?
A:
[23-166]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
N
M
V
S
G
V
L
T
L
A
E
R
S
I
R
S
I
M
T
P
R
T
D
V
S
W
V
N
I
D
D
D
A
-
A
T
I
R
Q
Q
L
T
A
A
P
H
S
F
F
P
V
C
R
G
-
S
-
L
-
D
E
V
V
G
I
G
R
A
K
D
L
V
--
A
D
L
I
T
E
-
G
R
V
R
R
N
R
L
R
----
D
P
I
I
-
V
H
E
S
I
G
I
L
R
L
M
D
T
L
K
R
S
R
G
Q
L
V
L
V
A
D
E
--------
F
G
A
I
E
G
L
V
T
P
I
D
V
F
E
A
I
A
G
E
F
P
D
E
---
D
E
L
P
-----------------------------------------------------------------------------------
26
HHSearch
57.57
29%
-127
- C1 -
3LHH
1
?
A:
[43-167]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
S
S
L
M
V
P
R
S
D
I
V
F
L
D
L
N
-
L
P
L
D
A
N
L
R
T
V
M
Q
S
P
H
S
R
F
P
V
C
R
N
---
N
V
D
D
M
V
G
I
I
S
A
K
Q
L
L
--
S
E
S
I
A
G
----
E
R
L
E
L
V
D
L
-
V
K
N
C
N
F
V
P
N
S
L
S
G
M
E
L
L
E
H
F
R
T
T
G
S
Q
M
V
F
V
V
D
E
--------
Y
G
D
L
K
G
L
V
T
L
Q
D
M
M
D
A
L
T
G
E
F
F
--------------------------------------------------------------------------------------------
33
HHSearch
57.15
30%
-94
- C- -
3OCO
-
?
A:
[211-346]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
N
F
M
Q
R
A
F
E
M
N
D
K
V
A
S
D
V
M
V
D
R
T
S
M
S
V
V
D
V
D
-
E
T
I
A
D
A
L
L
L
Y
L
E
E
Q
Y
S
R
F
P
V
T
A
D
-
N
D
K
-
D
K
I
I
G
Y
A
Y
N
Y
D
I
V
--
R
Q
A
R
I
D
----
D
K
A
K
I
S
T
I
-
M
R
D
I
V
S
V
P
E
N
M
K
V
P
D
V
M
E
E
M
S
A
H
R
V
P
M
A
I
V
I
D
E
--------
Y
G
G
T
S
G
I
I
T
D
K
D
V
Y
E
E
L
F
G
-----------------------------------------------------------------------------------------------
10
PsiBlast_PDB
55.67
27%
-92
- C- -
3OCO
-
?
A:
[211-346]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
N
F
M
Q
R
A
F
E
M
N
D
K
V
A
S
D
V
M
V
D
R
T
S
M
S
V
V
D
V
D
E
-
T
I
A
D
A
L
L
L
Y
L
E
E
Q
Y
S
R
F
P
V
T
A
D
N
D
-
K
-
D
K
I
I
G
Y
A
Y
N
Y
D
I
V
--
R
Q
A
R
I
D
D
----
K
A
K
I
S
T
I
-
M
R
D
I
V
S
V
P
E
N
M
K
V
P
D
V
M
E
E
M
S
A
H
R
V
P
M
A
I
V
I
D
E
--------
Y
G
G
T
S
G
I
I
T
D
K
D
V
Y
E
E
L
F
G
-----------------------------------------------------------------------------------------------
7
PsiBlast_PDB
54.21
33%
-63
- C1 -
3NQR
1
CORC_SALTY
A:
[3-124]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
R
V
-
R
D
I
M
I
P
R
S
Q
M
I
T
L
K
R
N
Q
-
T
L
D
E
C
L
D
V
I
I
E
S
A
H
S
R
F
P
V
I
S
E
-
D
-
K
-
D
H
I
E
G
I
L
M
A
K
D
L
L
PF
M
R
S
D
A
E
A
F
S
M
D
K
-----
V
-
L
R
T
A
V
V
V
P
E
S
K
R
V
D
R
M
L
K
E
F
R
S
Q
R
Y
H
M
A
I
V
I
D
E
--------
F
G
G
V
S
G
L
V
T
I
E
D
I
L
E
L
I
-------------------------------------------------------------------------------------------------
47
Fugue
52.35
21%
-98
- C1 -
4IY4
-
CNNM2_HUMAN
A:
[429-580]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
E
L
N
I
I
Q
G
A
L
E
L
R
T
K
T
V
E
D
V
M
T
P
L
R
D
C
F
M
I
T
G
E
A
I
L
D
F
N
T
M
S
E
I
M
E
S
G
Y
T
R
I
P
V
F
E
G
-
E
-
R
-
S
N
I
V
D
L
L
F
V
K
D
L
A
--
F
V
-
D
P
D
D
C
T
P
L
K
T
I
T
K
F
Y
-
N
H
P
L
H
F
V
F
N
D
T
K
L
D
A
M
L
E
E
F
K
K
G
K
S
H
L
A
I
V
Q
R
V
N
NEGE
G
D
P
F
Y
E
V
L
G
I
V
I
L
E
D
V
I
E
E
I
I
K
S
E
---------------------------------------------------------------------------------------------