@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu25150: (2016-07-09 )
MFSPQQPMRNYPQPGPPRPMPNQRMMGRRPPNMRGPSFGAQQQGFQQAGQFLPQANAGARNGAGAGGGLKGMLSRFLPGGGGAGSAGVPGIPGAGAAASGGAGLQGIQNIANPASLSSMLGNVQKVLGMAQQVTPMIQQYGPLVRNLPAMMKLYSQLSKSDDTETEANEESEKQSVSEESSEKEKETETKTSDGNKKSKPKSSSLPKKSKTTDNKEQELKTSAPKKKEAASPAPKRTSGSSKPRLYI
Atome Classification :
(20 SA)
-----------------------------------------------------------------.........10.......-.20........30........40........50.......------.60........70--.........80........-90..---..-------.....100.----....-..110.-......120...--...-----.130...------------.....140..---------...----------..150...------------....160-..-------------------.....------.170.......180...------....190......----.200.......210.......220.-......230-......------.240....-.-------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------------------------------------------MFSPQ
Q
P
M
RNYPQPGPPR-PMPNQRMMGRRPPNMRGPSF
G
A
Q
Q
Q
G
F
Q
Q
A
G
Q
FLPQANAG------ARNGAGAGG
G
L
K
---
G
M
L
S
R
FLPGGGGAGSAGVP-G-IP---GA-------GAAASGGA
G
----
L
Q
G
I
-
Q
N
IA
N
P
-
A
S
L
S
S
M
L
G
N
V
Q
K
--
V
L
G
-----
M
A
-
Q
Q
V
T
------------
P
M
I
Q
Q
Y
G
P
L
V
---------
R
N
L
----------
P
A
M
M
K
L
Y
S
------------
Q
LSKS-D-DT-------------------ETEAN------
E
E
S
E
K
Q
SVSEESSE
K
E
K------ETETKTSDGNKKS----KPKSSSLPKKSKTTD
N
K
E
Q
E
L
KTSA-PKKKEAASP-APKRTS------GSSK
P
R
LY-I-------------------------------------------------------
20
Fugue
65.32
18%
130
* C7 *
4NQI
1
?
A:
[14-243]
-------------------------------------------------------------------------------------
N
P
V
I
E
I
T
L
K
T
I
N
N
L
K
V
N
S
P
P
L
F
T
E
V
I
K
A
A
N
K
Y
Q
Q
Q
A
Q
A
L
------
S
Q
A
G
L
V
L
A
D
T
L
T
---
R
L
T
I
H
-----------------------------------
N
G
G
D
F
----
G
E
G
F
-
K
K
L
A
D
A
I
K
D
L
E
N
R
R
D
D
V
A
K
--
V
L
------
L
N
-
E
F
I
T
------------
P
N
K
Q
A
I
E
D
D
Q
---------
K
A
I
----------
A
T
F
E
K
N
Y
K
------------
K
D
R
D
Q
M
R
-
Q
D
-------------------
I
L
K
L
E
------
A
K
T
R
K
A
G
K
I
T
E
L
N
D
K
I
K
------
E
S
E
Q
L
N
A
N
K
L
R
D
V
V
L
M
E
R
R
K
H
A
T
F
L
S
Q
F
N
Q
F
L
E
K
E
I
E
L
S
A
D
T
M
S
K
F
S
T
N
L
N
T
-
H
R
D
L
I
N
------
S
Q
S
Q
L
P
L
E
M
E
S
M
I
S
K
Q
E
R-----------------------------------------------
8
PsiBlast_PDB
56.31
33%
-3
- C6 -
2W4U
-
TPM1_RABIT
A:
[170-232]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
A
E
E
R
A
E
L
S
E
G
K
C
A
E
L
------
E
E
E
L
K
T
V
T
N
N
L
K
S
----
L
E
A
Q
A
E
--
K
Y
S
Q
K
E
D
K
Y
E
E
E
I
K
V
L
S
-
D
K
L
K
E
A
E
T
R
-
A
----------------------------------------------------------------------------
21
Fugue
55.52
14%
64
* C5 *
1B0P
1
POR_DESAF
A:
[1-257]
----------------------------------------------G
K
K
M
M
T
T
D
G
N
T
A
T
A
H
V
A
Y
A
M
S
E
V
A
A
I
Y
P
I
T
P
S
S
T
M
G
E
-
E
A
D
D
W
A
A
Q
G
R
K
N
I
F
G
Q
T
L
T
I
R
E
M
Q
S
E
A
G
A
A
G
A
V
H
G
A
L
A
A
G
------
A
L
T
T
T
F
T
A
S
Q
G
L
---
L
L
M
I
P
N
M
Y
K
I
S
G
E
L
L
P
G
V
F
-
H
-
V
T
A
R
A
I
A
-------
A
H
A
L
S
I
F
G
D
----
H
Q
D
I
-
Y
A
A
R
Q
T
-
G
F
A
M
L
A
S
S
S
V
Q
E
--
A
H
D
-----
M
A
-
L
V
A
H
------------
L
A
A
I
E
S
--------------
N
V
----------
P
F
M
H
F
F
D
G
------------
F
R
T
S
H
-
E
-
I
Q
-------------------
K
I
E
V
L
------
D
Y
A
D
M
A
S
L
V
--
N
Q
K
A
L
A
------
E
F
R
A
K
S
M
N
P
E
H
P
H
----
V
R
G
T
A
Q
N
P
D
I
Y
F
Q
G
R
E
A
A
N
P
Y
Y
L
K
V
-
P
G
I
V
A
E
Y
M
Q
-
K
V
A
S
L
T
------
G
R
S
Y
-------------------------------------------------------------
1
PsiBlast_PDB
55.30
28%
-112
- C6 -
1UDX
2
OBG_THET8
A:
[210-290]
----------------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
I
P
-
G
-
I
I
----
E
-------
G
A
S
E
G
K
G
L
G
----
L
E
F
L
-
R
H
I
A
R
T
-
R
V
L
L
Y
V
L
D
A
A
D
E
--
P
L
K
-----
T
L
-
E
T
L
R
------------
K
E
V
G
A
Y
D
P
A
L
---------
L
R
R
----------
P
S
L
V
A
----------------
L
N
K
V
-
D
-
L
L
-------------------
E
E
E
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
54.71
31%
138
- C6 -
2EFS
-
GCN4_YEAST (first)
A:
[154-239]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
E
E
------------
L
L
S
K
N
-
Y
-
H
L
-------------------
E
N
E
V
A
R
L
K
K
L
L
E
R
A
E
E
R
A
E
L
S
E
G
K
S
A
E
L
------
E
E
E
L
K
T
V
T
N
N
L
K
S
----
L
E
A
Q
A
E
--
K
Y
S
Q
K
E
D
K
Y
E
E
E
I
K
V
L
S
-
D
K
L
K
E
A
E
T
R
-
A
----------------------------------------------------------------------------
24
Fugue
53.10
10%
65
- C5 -
3R4V
1
?
A:
[2-315]
----------------------------------------------PVK
V
C
L
I
F
A
G
G
T
G
M
N
V
A
T
K
L
V
D
L
G
E
A
V
H
C
F
D
T
C
D
K
N
V
-
V
D
V
H
R
S
V
N
V
T
L
T
K
G
T
R
G
N
R
K
V
I
L
P
L
V
R
P
Q
I
P
A
L
M
D
T
I
P
E
A
D
F
Y
I
V
C
Y
S
L
G
G
G
S
G
S
V
L
G
---
P
L
I
T
G
Q
L
A
D
R
K
A
S
F
V
S
F
V
V
-
G
A
M
E
---
S
T
-------
D
N
L
G
N
D
I
D
T
----
M
K
T
L
-
E
A
I
A
V
N
-
K
H
L
P
I
V
V
N
Y
V
P
N
--
T
Q
G
RS
Y
E
S
I
N
-
D
E
I
A
------------
E
K
I
R
K
V
V
L
L
V
NQNHGRLD
V
H
D
V
----------
A
N
W
V
R
F
T
D
KHNY
L
I
P
Q
V
C
E
L
H
I
E
T
T
-
R
-
K
D
-------------------
A
E
N
V
P
------
E
A
I
S
Q
L
S
L
Y
L
D
P
S
K
E
V
A
FGTPI
Y
R
K
V
G
I
M
K
V
D
D
L
D
V
----
T
D
D
Q
I
H
F
V
I
N
S
V
G
V
V
E
I
M
K
T
I
T
D
S
K
-
L
E
M
T
R
Q
Q
S
K
-
F
T
Q
R
N
P
IIDADD
N
V
D
E
D
G
M
V
-
V
-------------------------------------------------------
23
Fugue
50.83
14%
-142
* C6 *
4W7Z
8
BAP29_HUMAN
A:
[1-64]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
M
-------------------
D
E
E
C
V
------
L
E
A
E
N
K
K
L
V
E
D
Q
E
K
L
K
T
------
E
L
R
K
T
S
D
A
L
S
K
A
Q
----
N
D
V
M
E
M
K
M
Q
S
E
R
L
S
K
E
Y
D
Q
L
L
K
E
H
S
-
E
L
-------------------------------------------------------------------------------------
4
PsiBlast_PDB
50.53
31%
215
- C6 -
2D3E
-
GCN4_YEAST (first)
A:
[154-239]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
E
E
------------
L
L
S
K
N
-
Y
-
H
L
-------------------
E
N
E
V
A
R
L
K
K
L
L
E
R
A
E
E
R
A
E
L
S
E
G
K
C
A
E
L
------
E
E
E
L
K
T
V
T
N
N
L
K
S
----
L
E
A
Q
A
E
--
K
Y
S
Q
K
E
D
K
Y
E
E
E
I
K
V
L
S
-
D
K
L
K
E
A
E
T
R
-
A
----------------------------------------------------------------------------
2
PsiBlast_PDB
48.83
31%
272
- C6 -
2EFR
-
GCN4_YEAST (first)
A:
[154-239]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
E
E
------------
L
L
S
K
N
-
Y
-
H
L
-------------------
E
N
E
V
A
R
L
K
K
L
L
E
R
A
E
E
R
A
E
L
S
E
G
K
S
A
E
L
------
E
E
E
L
K
T
V
T
N
N
L
K
S
----
L
E
A
Q
A
E
--
K
Y
S
Q
K
E
D
K
Y
E
E
E
I
K
V
L
S
-
D
K
L
K
E
A
E
T
R
-
A
----------------------------------------------------------------------------
9
PsiBlast_PDB
45.55
28%
31
- C6 -
3MAJ
1
?
A:
[131-253]
------------------------------------------------------------------------------------------------------------------------
A
I
V
G
------
S
R
N
A
S
G
A
G
L
K
F
A
---
G
Q
L
A
A
D
L
G
A
A
G
F
V
V
I
S
G
L
A
R
G
-
I
D
---
Q
A
-------
A
H
R
A
S
L
S
S
G
T
V
A
V
L
A
G
G
-
H
D
K
I
Y
P
-
A
E
H
E
D
L
L
L
D
I
I
Q
--
T
R
G
-----
A
A
-
I
S
E
M
------------
P
L
--
G
H
V
P
R
G
---------
K
D
F
----------
P
R
R
N
R
L
I
S
------------
G
A
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
43.94
33%
-
- C6 -
2TMA
-
TPM1_RABIT
A:
[177-239]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
A
E
E
R
A
E
L
S
E
G
K
C
A
E
L
------
E
E
E
I
K
T
V
T
N
N
L
K
S
----
L
E
A
Q
A
E
--
K
Y
S
Q
K
E
D
K
Y
E
E
E
I
K
V
L
S
-
D
K
L
K
E
A
E
T
R
-
A
----------------------------------------------------------------------------
6
PsiBlast_PDB
43.87
33%
198
- C6 -
1C1G
-
TPM1_PIG
A:
[177-239]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
A
E
E
R
A
E
L
S
E
G
K
C
A
E
L
------
E
E
E
I
K
T
V
T
N
N
L
K
S
----
L
E
A
Q
A
E
--
K
Y
S
Q
K
E
D
K
Y
E
E
E
I
K
V
L
S
-
D
K
L
K
E
A
E
T
R
-
A
----------------------------------------------------------------------------
7
PsiBlast_PDB
42.67
33%
0
- C- -
2W49
-
TPM1_RABIT
A:
[170-232]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
A
E
E
R
A
E
L
S
E
G
K
C
A
E
L
------
E
E
E
L
K
T
V
T
N
N
L
K
S
----
L
E
A
Q
A
E
--
K
Y
S
Q
K
E
D
K
Y
E
E
E
I
K
V
L
S
-
D
K
L
K
E
A
E
T
R
-
A
----------------------------------------------------------------------------
18
Fugue
39.36
8%
11
- C5 -
3P0K
3
VP33_NPVAC
A:
[2-259]
-----------------------------------------------------------------
G
I
P
L
T
P
L
F
S
R
Y
K
D
S
Y
L
L
Y
-
S
F
R
L
I
D
L
L
R
A
S
K
S
-------
T
H
L
T
K
L
L
S
S
Q
A
T
Y
L
Y
H
F
A
C
L
------
M
K
Y
K
D
I
Q
K
Y
E
V
Q
---
Q
L
I
E
W
A
I
N
A
S
P
D
M
D
L
Q
Q
F
R
-
I
-
E
F
---
M
D
-------
K
T
T
E
L
N
-------
L
R
S
C
-
Q
P
K
S
F
T
-
Y
T
F
T
T
I
W
D
T
M
H
F
--
L
S
L
-----
I
I
-
D
D
M
V
Y
T
RDKSS
L
D
F
V
M
Q
Q
L
K
T
M
K
V
L
F
---------
Y
N
V
FFILQC
A
M
C
R
D
H
Y
M
N
V
K
G
------------
F
I
I
Y
H
-
I
-
E
L
-------------------
I
E
I
A
L
------
D
K
E
K
Y
G
T
D
I
T
F
V
D
S
Y
Q
Q
------
E
T
A
G
A
D
V
A
V
V
S
N
N
----
M
L
M
K
N
L
M
A
Y
V
S
M
T
F
H
N
H
I
N
D
Y
K
W
I
Q
-
R
N
K
K
P
P
-
A
H
-
Y
E
R
M
T
W
------
G
E
Y
K
K
L
L
N
-
L
-------------------------------------------------------
22
Fugue
38.27
14%
142
- C6 -
2KZ9
-
VATE_YEAST
A:
[1-69]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
S
------------
A
I
T
A
L
-
T
-
P
N
-------------------
Q
V
N
D
E
------
L
N
K
M
Q
A
F
I
R
K
E
A
E
E
K
A
K
------
E
I
Q
L
K
A
D
Q
E
Y
E
I
E
----
K
T
N
I
V
R
N
E
T
N
N
I
D
G
N
F
K
S
K
L
K
K
A
------------------------------------------------------------------------------------------
25
Fugue
37.56
6%
51
- C5 -
1Z2C
1
DIAP1_MOUSE
B:
[15-375]
V
L
V
L
F
E
Q
M
L
V
D
M
NLNEEKQ
Q
P
L
R
E
KD
I
V
I
K
R
E
M
V
S
Q
Y
L
H
T
SSSRS
A
M
M
Y
I
Q
E
L
R
S
GLRD
M
H
L
L
S
C
L
E
S
L
R
V
S
L
N
N
N
P
V
S
W
V
Q
T
F
G
A
E
G
L
A
S
L
L
D
I
L
K
R
L
H
D
E
K
D
S
R
N
Q
H
E
I
I
R
C
L
K
A
F
M
N
N
K
F
G
------
I
K
T
M
L
E
T
E
E
G
I
L
---
L
L
V
R
A
M
D
P
A
V
P
N
M
M
I
D
A
A
K
-
L
-
L
S
---
A
L
C
I
LPQPE
D
M
N
E
R
V
L
E
A
----
M
T
E
R
-
A
E
M
D
E
V
-
E
R
F
Q
P
L
L
D
G
L
K
S
GT
S
I
A
-----
L
K
-
V
G
C
L
------------
Q
L
I
N
A
L
I
T
P
A
---------
E
E
L
----------
D
F
R
V
H
I
R
S
------------
E
L
M
R
L
-
G
L
H
Q
-------------------
V
L
Q
E
L
------
R
E
I
E
N
E
D
M
K
V
Q
L
C
V
F
D
E
------
Q
G
D
E
D
F
F
D
L
K
G
R
L
----
D
D
I
R
M
E
M
D
D
F
G
E
V
F
Q
I
I
L
N
T
V
K
D
S
K
-
A
E
P
H
F
L
S
I
L
-
Q
H
L
L
L
V
------
R
N
D
Y
E
A
R
P
-
Q
Y
Y
K
L
I
E
E
C
V
S
Q
I
V
LHKNGTDPDF--------------------------------
14
HHSearch
36.90
17%
-192
- C6 -
2ZOP
-
CMR5_THET8
A:
[23-40]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
G
R
G
E
Y
R
D
M
A
---------
L
K
L
----------
P
V
L
V
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
34.64
8%
101
- C7 -
2P03
-
AMRP_HUMAN
A:
[1-323]
-----------------------------------------------------------------
Y
S
R
E
K
N
Q
P
K
P
S
P
K
R
E
S
G
E
-
E
F
R
M
E
K
L
N
Q
L
W
E
K
A
Q
R
L
H
L
P
P
V
R
L
A
E
L
H
A
D
L
K
I
Q
E
R
D
E
L
A
------
W
K
K
L
K
L
D
G
L
D
E
D
---
G
E
K
E
A
R
L
I
R
N
L
N
V
I
L
A
K
Y
G
-
L
-
D
G
---
K
K
-------
D
A
R
Q
V
T
S
N
S
----
L
S
G
T
Q
E
D
G
L
D
D
-
P
R
L
E
K
L
W
H
K
A
K
T
--
S
G
K
-----
F
S
G
E
E
L
D
------------
K
L
W
R
E
F
L
H
H
K
---------
E
K
V
----------
H
E
Y
N
V
L
L
E
------------
T
L
S
R
T
-
E
-
E
I
HENVISPSDLSDIKGSVL
H
S
R
H
T
E
------
L
K
E
K
L
R
S
I
N
Q
G
L
D
R
L
R
R
------
V
S
H
Q
G
Y
S
T
E
A
E
F
E
----
E
P
R
V
I
D
L
W
D
L
A
Q
S
A
N
L
T
D
K
E
L
E
A
F
R
-
E
E
L
K
H
F
E
A
K
-
I
E
K
H
N
H
------
Y
Q
K
Q
L
E
I
A
-
H
E
K
L
R
H
A
E
S
VGDGER
V
S
R
S
R
E
K
H
A
L
L
E
G
R
T
K
E
L
G
Y
T
V
K
K
H
L
Q
D
L
S
G
R
ISRARHNEL
19
Fugue
33.52
11%
206
- C6 -
1UIX
-
ROCK2_BOVIN
A:
[-2-1045]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
S
D
V
A
N
L
A
N
E
K
E
E
L
N
N
------
K
L
K
E
A
Q
E
Q
L
S
R
L
K
----
D
E
E
I
S
A
A
A
I
K
A
Q
F
E
K
Q
L
L
T
E
R
T
L
K
T
-
Q
A
V
N
K
L
A
E
I
M
N
R
K
--------------------------------------------------------------------------
10
PsiBlast_PDB
32.36
32%
-16
* C8 *
4D7U
1
?
A:
[143-198]
------------------------------------------------------------------------------------------------------------------
G
Q
Y
L
M
R
A
E
L
I
------
A
L
H
N
A
G
S
Q
A
G
A
Q
F
Y
I
G
C
A
Q
I
N
V
T
G
G
G
S
A
S
P
S
N
T
V
-
S
-
F
P
---
G
A
-------
Y
S
A
S
D
P
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------