@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu26610: (2016-07-11 )
MTTINLIIFTLLIVLTAFFVATEFAIVKIRSSKIDQLILEGKKGAISAKKVITHLDEYLSACQLGITVTALGIGWVGESTFEVILHPLFAHFHVSETVSHVLILVIAFVMATFLHVVVGELAPKTLAIQKAETITLLTAKPIIWFYRILFPFIWFLNGSARFIVGLFGLKPASEHELAHSEEELRILLSESYKSGEINQNELKYVNNIFEFDERIAKEIMIPRREIVAISSEDSYETIVKIIKTESYTRYPVLNGDKDSIIGFINAKEFLSAYIDTDQKIKEDFKLENHINPVIHVIESVPIHDVLVKMQKERTHIAILVDEYGGTSGLVTAEDILEEIVGEIRDEFDKDEVPNIRKVNDNHYILDSKVLIEDVNDLLGTTLASDEVDTIGGWFMTQQIDAAVGSVIEADGYIFKVHETVGRHINYLEIVRKKE
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230..--.....240.......250.-...-...260.......270.......280.-......290........300.......310.......320--------.......330.......340.......350.......360.......370.......380.......390.......-400.........410.......420.......430..
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MT
T
I
N
L
I
I
F
T
L
L
I
V
L
T
A
F
F
V
A
T
E
F
A
I
V
K
I
RSSK
I
D
Q
L
I
LEGKKGA
I
S
A
K
K
V
I
T
H
L
D
E
Y
L
S
A
C
QLG
I
T
V
T
A
L
G
IGWVG
E
S
T
F
E
V
I
L
H
P
L
F
A
H
F
H
V
S
E
T
V
S
H
V
L
I
L
V
I
A
F
V
M
A
T
F
L
H
V
V
V
G
ELAPK
T
L
A
I
Q
KA
E
T
I
T
L
L
TA
K
P
I
I
W
F
Y
R
I
L
F
P
F
I
W
F
LNGS
A
R
F
I
V
G
L
FGLKPA
S
E
H
E
LAH
S
E
E
E
L
R
I
L
L
S
ESYKSGEI
N
Q
N
E
L
K
Y
V
N
N
I
F
E
F
D
E
R
I
A
K
E
IMIPR
R
E
I
V
A
ISSED
S
--
Y
E
T
I
V
K
I
I
KTESYTRYPVL-NGD-KD
S
I
I
G
F
I
N
A
K
E
F
L
S
A
Y
IDT
D
Q
K
I
K
E
D
-FKLENHI-
N
P
V
I
H
V
I
E
SV
P
I
H
D
V
L
V
K
M
Q
KER
T
H
I
A
I
L
V
DE--------YGGTSGLV
T
A
E
D
I
L
E
E
I
V
G
E
I
R
D
EFDKDEVPN
I
R
KVNDN
H
Y
I
LD
S
K
V
L
I
E
D
V
N
D
L
LGTTLASDEV
D
T
I
G
G
W
F
M
T
Q
Q
I
-
D
--
A
A
V
G
S
VIEAD
G
Y
I
F
K
V
H
E
T
VGRH
I
N
Y
L
E
I
V
RKKE
49
HHSearch
86.35
32%
-102
* C1 *
4HG0
1
CORC_ECOLI
A:
[51-282]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
D
T
R
D
M
L
E
G
V
M
D
I
A
D
Q
R
V
R
D
I
M
I
P
R
S
Q
M
I
T
L
K
R
N
Q
T
--
L
D
E
C
L
D
V
I
I
E
S
A
H
S
R
F
P
V
I
-
S
E
D
-
K
D
H
I
E
G
I
L
M
A
K
D
L
L
P
F
M
R
S
D
----
A
E
A
-
F
S
M
D
K
V
L
-
R
Q
A
V
V
V
P
E
S
K
R
V
D
R
M
L
K
E
F
R
S
Q
R
Y
H
M
A
I
V
I
D
E
--------
F
G
G
V
S
G
L
V
T
I
E
D
I
L
E
L
I
V
G
E
I
E
D
E
Y
D
E
E
D
D
I
D
F
R
Q
L
S
R
H
T
W
T
V
R
A
L
A
S
I
E
D
F
N
E
A
F
G
T
H
F
S
D
E
E
V
D
T
I
G
G
L
V
M
Q
A
F
G
H
L
--
P
A
R
G
E
T
I
D
I
D
G
Y
Q
F
K
V
A
M
A
D
S
R
R
I
I
Q
V
H
V
K
I
P
--
2
PsiBlast_PDB
85.95
32%
-129
- C1 -
4HG0
1
CORC_ECOLI
A:
[51-274]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
D
T
R
D
M
L
E
G
V
M
D
I
A
D
Q
R
V
R
D
I
M
I
P
R
S
Q
M
I
T
L
K
R
N
Q
T
--
L
D
E
C
L
D
V
I
I
E
S
A
H
S
R
F
P
V
I
-
S
E
D
-
K
D
H
I
E
G
I
L
M
A
K
D
L
L
-
P
F
M
R
S
D
---
A
E
A
-
F
S
M
D
K
V
L
-
R
Q
A
V
V
V
P
E
S
K
R
V
D
R
M
L
K
E
F
R
S
Q
R
Y
H
M
A
I
V
I
D
E
--------
F
G
G
V
S
G
L
V
T
I
E
D
I
L
E
L
I
V
G
E
I
E
D
E
Y
D
E
E
D
D
I
D
F
R
Q
L
S
R
H
T
W
T
V
R
A
L
A
S
I
E
D
F
N
E
A
F
G
T
H
F
S
D
E
E
V
D
T
I
G
G
-
L
V
M
Q
A
F
-
G
HL
P
A
R
G
E
T
I
D
I
D
G
Y
Q
F
K
V
A
M
A
D
S
R
R
I
----------
3
PsiBlast_PDB
78.10
30%
-165
- C1 -
3OI8
4
?
A:
[4-156]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
A
E
D
V
L
N
L
L
R
Q
A
H
E
Q
E
V
F
D
A
D
T
L
L
R
L
E
K
V
L
D
F
S
D
L
E
V
R
D
A
M
I
T
R
S
R
M
N
V
L
K
E
N
D
S
--
I
E
R
I
T
A
Y
V
I
D
T
A
H
S
R
F
P
V
I
-
G
E
D
-
K
D
E
V
L
G
I
L
H
A
K
D
L
L
K
Y
M
F
N
P
E
Q
------
F
H
L
K
S
I
L
-
R
P
A
V
F
V
P
E
G
K
S
L
T
A
L
L
K
E
F
R
E
Q
R
N
H
M
A
I
V
I
D
E
--------
Y
G
G
T
S
G
L
V
T
F
E
D
I
I
E
----------------------------------------------------------------------------------------------------
51
HHSearch
77.52
32%
-165
- C1 -
3OI8
4
?
A:
[2-156]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
A
S
A
E
D
V
L
N
L
L
R
Q
A
H
E
Q
E
V
F
D
A
D
T
L
L
R
L
E
K
V
L
D
F
S
D
L
E
V
R
D
A
M
I
T
R
S
R
M
N
V
L
K
E
N
D
S
--
I
E
R
I
T
A
Y
V
I
D
T
A
H
S
R
F
P
V
I
-
G
E
D
-
K
D
E
V
L
G
I
L
H
A
K
D
L
L
K
Y
M
F
N
P
-----
E
Q
-
F
H
L
K
S
I
L
-
R
P
A
V
F
V
P
E
G
K
S
L
T
A
L
L
K
E
F
R
E
Q
R
N
H
M
A
I
V
I
D
E
--------
Y
G
G
T
S
G
L
V
T
F
E
D
I
I
E
----------------------------------------------------------------------------------------------------
56
HHSearch
76.83
46%
-155
- C1 -
3LV9
1
?
A:
[18-147]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
F
E
E
K
K
I
R
E
I
M
V
P
R
T
D
M
V
C
I
Y
E
S
D
S
--
E
E
K
I
L
A
I
L
K
E
E
G
V
T
R
Y
P
V
C
-
R
K
N
-
K
D
D
I
L
G
F
V
H
I
R
D
L
Y
N
Q
K
I
N
E
-----
N
K
-
I
E
L
E
E
I
L
-
R
D
I
I
Y
I
S
E
N
L
T
I
D
K
A
L
E
R
I
R
K
E
K
L
Q
L
A
I
V
V
D
E
--------
Y
G
G
T
S
G
V
V
T
I
E
D
I
L
E
E
I
V
G
E
I
----------------------------------------------------------------------------------------------
1
PsiBlast_PDB
71.00
45%
-99
- C1 -
3LV9
1
?
A:
[18-147]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
F
E
E
K
K
I
R
E
I
M
V
P
R
T
D
M
V
C
I
Y
E
S
D
S
--
E
E
K
I
L
A
I
L
K
E
E
G
V
T
R
Y
P
V
C
-
R
K
N
-
K
D
D
I
L
G
F
V
H
I
R
D
L
Y
N
------
Q
K
I
N
E
N
K
I
E
L
E
E
I
L
-
R
D
I
I
Y
I
S
E
N
L
T
I
D
K
A
L
E
R
I
R
K
E
K
L
Q
L
A
I
V
V
D
E
--------
Y
G
G
T
S
G
V
V
T
I
E
D
I
L
E
E
I
V
G
E
I
----------------------------------------------------------------------------------------------
6
PsiBlast_PDB
69.45
32%
-177
- C1 -
3JTF
4
?
A:
[4-128]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
T
V
A
D
I
M
V
P
R
S
R
M
D
L
L
D
I
S
Q
P
--
L
P
Q
L
L
A
T
I
I
E
T
A
H
S
R
F
P
V
Y
-
E
D
D
-
R
D
N
I
I
G
I
L
L
A
K
D
L
L
R
Y
M
L
E
P
A
L
D
I
R
-------
S
L
V
-
R
P
A
V
F
I
P
E
V
K
R
L
N
V
L
L
R
E
F
R
A
S
R
N
H
L
A
I
V
I
D
E
---------
G
G
I
S
G
L
V
T
M
E
D
V
L
E
Q
I
V
G
D
I
----------------------------------------------------------------------------------------------
9
PsiBlast_PDB
69.10
33%
-170
- C1 -
3HF7
1
?
A:
[6-127]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
M
V
P
R
N
E
I
V
G
I
D
I
N
D
D
--
W
K
S
I
V
R
Q
L
T
H
S
P
H
G
R
I
V
L
Y
-
R
D
S
-
L
D
D
A
I
S
M
L
R
V
R
E
A
Y
R
L
M
T
E
K
K
E
F
T
K
E
---
I
M
L
R
A
A
-
D
E
I
Y
F
V
P
E
G
T
P
L
S
T
Q
L
V
K
F
Q
R
N
K
K
K
V
G
L
V
V
D
E
--------
Y
G
D
I
Q
G
L
V
T
V
E
D
I
L
E
E
I
V
G
------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
69.08
35%
-163
- C1 -
3NQR
1
CORC_SALTY
A:
[3-124]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
R
V
-
R
D
I
M
I
P
R
S
Q
M
I
T
L
K
R
N
Q
T
--
L
D
E
C
L
D
V
I
I
E
S
A
H
S
R
F
P
V
I
-
S
E
D
-
K
D
H
I
E
G
I
L
M
A
K
D
L
L
-
P
F
M
R
S
D
---
A
E
A
-
F
S
M
D
K
V
L
-
R
T
A
V
V
V
P
E
S
K
R
V
D
R
M
L
K
E
F
R
S
Q
R
Y
H
M
A
I
V
I
D
E
--------
F
G
G
V
S
G
L
V
T
I
E
D
I
L
E
L
I
--------------------------------------------------------------------------------------------------
50
HHSearch
68.50
28%
-181
- C1 -
3LHH
1
?
A:
[43-167]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
S
S
L
M
V
P
R
S
D
I
V
F
L
D
L
N
L
P
--
L
D
A
N
L
R
T
V
M
Q
S
P
H
S
R
F
P
V
C
-
R
N
N
-
V
D
D
M
V
G
I
I
S
A
K
Q
L
L
S
E
S
I
A
G
-----
E
R
-
L
E
L
V
D
L
V
-
K
N
C
N
F
V
P
N
S
L
S
G
M
E
L
L
E
H
F
R
T
T
G
S
Q
M
V
F
V
V
D
E
--------
Y
G
D
L
K
G
L
V
T
L
Q
D
M
M
D
A
L
T
G
E
F
F
---------------------------------------------------------------------------------------------
10
PsiBlast_PDB
68.28
28%
-152
- C1 -
3OCM
7
?
A:
[23-166]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
N
M
V
S
G
V
L
T
L
A
E
R
S
I
R
S
I
M
T
P
R
T
D
V
S
W
V
N
I
D
D
D
--
A
A
T
I
R
Q
Q
L
T
A
A
P
H
S
F
F
P
V
C
-
R
G
S
-
L
D
E
V
V
G
I
G
R
A
K
D
L
V
A
D
L
I
-
T
E
G
R
V
R
R
------
N
R
L
-
R
D
P
I
I
V
H
E
S
I
G
I
L
R
L
M
D
T
L
K
R
S
R
G
Q
L
V
L
V
A
D
E
--------
F
G
A
I
E
G
L
V
T
P
I
D
V
F
E
A
I
A
G
E
F
P
D
E
---
D
E
L
P
------------------------------------------------------------------------------------
39
Fugue
68.26
31%
-158
- C1 -
3HF7
1
?
A:
[1-127]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
S
V
N
D
I
M
V
P
R
N
E
I
V
G
I
D
I
N
D
D
--
W
K
S
I
V
R
Q
L
T
H
S
P
H
G
R
I
V
L
Y
-
R
D
S
-
L
D
D
A
I
S
M
L
R
V
R
E
A
Y
R
L
M
T
E
K
K
E
F
--
T
K
-
E
I
M
L
R
A
A
-
D
E
I
Y
F
V
P
E
G
T
P
L
S
T
Q
L
V
K
F
Q
R
N
K
K
K
V
G
L
V
V
D
E
--------
Y
G
D
I
Q
G
L
V
T
V
E
D
I
L
E
E
I
V
G
------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
67.87
27%
-180
- C1 -
3LHH
1
?
A:
[43-165]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
S
S
L
M
V
P
R
S
D
I
V
F
L
D
L
N
L
P
--
L
D
A
N
L
R
T
V
M
Q
S
P
H
S
R
F
P
V
C
-
R
N
N
-
V
D
D
M
V
G
I
I
S
A
K
Q
L
L
S
E
S
I
-----
A
G
E
R
-
L
E
L
V
D
L
V
-
K
N
C
N
F
V
P
N
S
L
S
G
M
E
L
L
E
H
F
R
T
T
G
S
Q
M
V
F
V
V
D
E
--------
Y
G
D
L
K
G
L
V
T
L
Q
D
M
M
D
A
L
T
G
E
-----------------------------------------------------------------------------------------------
70
HHSearch
66.36
32%
-146
- C1 -
3LFR
2
?
A:
[3-125]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
V
R
D
I
M
V
P
R
S
Q
M
I
S
I
K
A
T
Q
T
--
P
R
E
F
L
P
A
V
I
D
A
A
H
S
R
Y
P
V
I
-
G
E
S
-
H
D
D
V
L
G
V
L
L
A
K
D
L
L
P
L
I
L
K
A
D
---
G
D
S
-
D
D
V
K
K
L
L
-
R
P
A
T
F
V
P
E
S
K
R
L
N
V
L
L
R
E
F
R
A
N
H
N
H
M
A
I
V
I
D
E
--------
Y
G
G
V
A
G
L
V
T
I
E
D
V
L
E
Q
I
--------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
65.07
33%
-138
- C1 -
3LFR
2
?
A:
[6-125]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
D
I
M
V
P
R
S
Q
M
I
S
I
K
A
T
Q
T
--
P
R
E
F
L
P
A
V
I
D
A
A
H
S
R
Y
P
V
I
-
G
E
S
-
H
D
D
V
L
G
V
L
L
A
K
D
L
L
P
L
I
L
K
A
D
G
D
S
D
D
V
-
K
K
L
---
L
-
R
P
A
T
F
V
P
E
S
K
R
L
N
V
L
L
R
E
F
R
A
N
H
N
H
M
A
I
V
I
D
E
--------
Y
G
G
V
A
G
L
V
T
I
E
D
V
L
E
Q
I
--------------------------------------------------------------------------------------------------
57
HHSearch
63.66
26%
-123
- C1 -
3OCM
7
?
A:
[18-166]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
F
G
V
E
E
R
N
M
V
S
G
V
L
T
L
A
E
R
S
I
R
S
I
M
T
P
R
T
D
V
S
W
V
N
I
D
D
D
--
A
A
T
I
R
Q
Q
L
T
A
A
P
H
S
F
F
P
V
C
-
R
G
S
-
L
D
E
V
V
G
I
G
R
A
K
D
L
V
A
D
L
I
T
E
--------
G
R
V
R
R
N
R
L
R
D
P
I
I
V
H
E
S
I
G
I
L
R
L
M
D
T
L
K
R
S
R
G
Q
L
V
L
V
A
D
E
--------
F
G
A
I
E
G
L
V
T
P
I
D
V
F
E
A
I
A
G
E
F
P
D
E
D
E
L
P
---------------------------------------------------------------------------------------
16
PsiBlast_PDB
62.40
28%
-165
- C1 -
3I8N
1
?
A:
[10-130]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
V
M
T
P
R
P
V
V
F
R
V
D
A
T
M
T
--
I
N
E
F
L
D
K
H
K
D
T
P
F
S
R
P
L
V
Y
-
S
E
Q
-
K
D
N
I
I
G
F
V
H
R
L
E
L
F
K
----
M
Q
Q
S
G
S
G
Q
-
K
Q
L
G
A
V
M
-
R
P
I
Q
V
V
L
N
N
T
A
L
P
K
V
F
D
Q
M
M
T
H
R
L
Q
L
A
L
V
V
D
E
--------
Y
G
T
V
L
G
L
V
T
L
E
D
I
F
E
H
L
V
G
E
-----------------------------------------------------------------------------------------------
8
PsiBlast_PDB
58.69
26%
-81
- C- -
3OCO
-
?
A:
[211-346]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
N
F
M
Q
R
A
F
E
M
N
D
K
V
A
S
D
V
M
V
D
R
T
S
M
S
V
V
D
V
D
E
T
--
I
A
D
A
L
L
L
Y
L
E
E
Q
Y
S
R
F
P
V
T
A
D
N
D
-
K
D
K
I
I
G
Y
A
Y
N
Y
D
I
V
R
Q
-----
A
R
I
D
D
K
-
A
K
I
S
T
I
M
-
R
D
I
V
S
V
P
E
N
M
K
V
P
D
V
M
E
E
M
S
A
H
R
V
P
M
A
I
V
I
D
E
--------
Y
G
G
T
S
G
I
I
T
D
K
D
V
Y
E
E
L
F
G
------------------------------------------------------------------------------------------------
59
HHSearch
58.50
28%
-91
- C- -
3OCO
-
?
A:
[211-346]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
N
F
M
Q
R
A
F
E
M
N
D
K
V
A
S
D
V
M
V
D
R
T
S
M
S
V
V
D
V
D
E
T
--
I
A
D
A
L
L
L
Y
L
E
E
Q
Y
S
R
F
P
V
T
-
A
D
N
D
K
D
K
I
I
G
Y
A
Y
N
Y
D
I
V
R
Q
A
R
I
D
-----
D
K
-
A
K
I
S
T
I
M
-
R
D
I
V
S
V
P
E
N
M
K
V
P
D
V
M
E
E
M
S
A
H
R
V
P
M
A
I
V
I
D
E
--------
Y
G
G
T
S
G
I
I
T
D
K
D
V
Y
E
E
L
F
G
------------------------------------------------------------------------------------------------
40
Fugue
54.63
26%
-35
- C1 -
4IY4
-
CNNM2_HUMAN
A:
[429-580]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
E
L
N
I
I
Q
G
A
L
E
L
R
T
K
T
V
E
D
V
M
T
P
L
R
D
C
F
M
I
T
G
E
A
I
LD
F
N
T
M
S
E
I
M
E
S
-
G
Y
T
R
I
P
V
F
-
E
G
E
-
R
S
N
I
V
D
L
L
F
V
K
D
L
A
F
V
D
P
D
D
C
T
P
L
K
T
I
-
T
K
F
Y
N
H
---
P
L
H
F
V
F
N
D
T
K
L
D
A
M
L
E
E
F
K
K
G
K
S
H
L
A
I
V
Q
R
V
N
NEGE
G
D
P
F
Y
E
V
L
G
I
V
I
L
E
D
V
I
E
E
I
I
K
S
E
----------------------------------------------------------------------------------------------