@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu29580: (2016-07-18 )
MNYDHILIRFGEISTKGKNRKSFIERLKQNIRLVLKDYPNLKYFSNRDRMTITLNGEDPEALFPHLKQVFGIQSFSLAIKCDSRLDDIKATALKAIKDQYKPGDTFKVATKRAYKQFELDTNQMNAEIGGHILRNTEGLTVDVRNPDIPLRIEIREEATFLTIRDEKGAGGLPVGSAGKAMLMLSGGFDSPVAGFYAMKRGLSVEAVHFFSPPYTSERAKQKVMDLAKCLSRFGGSMTLHIVPFTKTQELIQKQIPENYTMTATRRLMLQIADRIREKRNGLAIITGESLGQVASQTLESMYAINAVTSTPILRPLIAMDKTEIIEKSREIGTYETSIQPFEDCCTIFTPPSPKTRPKKEKIEHFESFVDFEPYIQEAVDNIETMTLYSEQEANDKFAELF
Atome Classification :
(20 SA)
.........10......-..-20.....-...30.--.......40---........50........60........70........80........90..----......100--..----..--.....110.......120.......130.......140.......150.......160.......170.......180.......190.......-200---.-----........210...--.-...220.......230..--..--.-.-.240.--......-250---.----.-----.---.----.----....260.......270.......280.......290.......300-------...---------...---...310.....--.--.-------320-.........330....--...340.-......350.......360.......-370.......380.......390.......400
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MNY
D
H
I
L
I
R
F
G
EISTKG-K
N
-
R
K
S
F
I
E
R
-
L
K
Q
N
I
R
--
L
V
L
KDYPNL---KYFSNR
D
R
M
T
I
T
LNGE
D
P
E
A
L
F
P
H
L
K
Q
V
FGIQ
S
F
S
L
A
I
K
CDSR
L
D
D
I
K
A
T
A
L
----
K
A
I
K
D
QY----KP----GD--
T
F
K
V
A
T
K
R
A
Y
K
QFELDTNQM
N
A
E
IG
G
H
I
LRNTE
G
L
T
V
DVRNPDI
P
L
R
I
E
I
REE
A
T
F
L
T
I
RDEKGAGGLPVGSA
G
K
A
M
L
M
L
SGGFDS
P
V
A
G
F
Y
A
M
K-R-----G-----L
S
V
E
A
V
H
F
FSPPY
T
--
S
-
E
R
A
K
Q
K
V
M
D
L
A
K
C
L
S
RFG--G
S
--
M
-
T
-
L
H
I
V
P--FT
K
T
Q
E
-
L
-----
I
----
Q
-----
K
---Q----I----PENY
T
M
T
A
T
R
R
L
M
L
Q
I
A
D
R
I
R
E
KRN
G
L
A
I
I
TG
E
S
L
G
Q
V
A
S
Q
T
L
E
S
---------
M
Y
A
---------
I
NA---VTSTP
I
L
R
P
L
I
--A--M-------
D
---
K
T
E
I
I
E
K
SREIGTYET--SIQ
P
F
E
D-C
C
T
I
FTPPSPKTR
P
K
K
E
K
I
E
H
F
E
S
FV-DF
E
P
Y
I
Q
E
A
V
DNI
E
T
M
T
L
YSEQEAN
D
K
F
A
ELF
30
Fugue
99.73
55%
-116
- C5 -
2C5S
1
THII_BACAN
A:
[13-401]
--
Y
E
Y
I
L
V
R
Y
G
E
M
---
G
-
K
N
-
R
S
K
F
V
S
T
-
L
K
D
N
V
K
--
F
K
L
K
K
F
P
N
I
---
K
I
D
A
T
H
D
R
M
Y
I
Q
L
N
G
E
D
H
E
A
V
S
E
R
L
K
D
V
F
G
I
H
K
F
N
L
A
M
K
V
P
S
E
L
E
D
I
K
K
G
A
L
----
A
A
F
L
Q
V
K
----
G
D
----
V
K
--
T
F
K
I
T
V
H
R
S
Y
K
H
F
P
M
R
T
M
E
L
L
P
E
I
G
G
H
I
L
E
N
T
E
D
I
T
V
D
V
H
N
P
D
V
N
V
R
V
E
I
R
S
G
Y
S
Y
I
M
C
D
E
R
M
G
A
G
G
L
P
V
G
V
G
G
K
V
M
V
L
L
S
G
G
I
D
S
P
V
A
A
Y
L
T
M
K
-
R
-----
G
-----
V
S
V
E
A
V
H
F
H
S
P
P
F
T
--
S
-
E
R
A
K
Q
K
V
I
D
L
A
Q
E
L
T
K
Y
C
--
K
R
--
V
-
T
-
L
H
L
V
P
--
F
T
E
V
Q
K
-
T
-----
I
----
N
-----
K
---
E
----
I
----
P
S
S
Y
S
M
T
V
M
R
R
M
M
M
R
I
T
E
R
I
A
E
E
R
N
A
L
A
I
T
T
G
E
S
L
G
Q
V
A
S
Q
T
L
D
S
---------
M
H
T
---------
I
N
E
---
V
T
N
Y
P
V
I
R
P
L
I
--
T
--
M
-------
D
---
K
L
E
I
I
K
I
A
E
E
I
G
T
Y
D
I
--
S
I
R
P
Y
---------------
K
P
K
R
E
K
A
N
R
F
E
A
K
Y
-
D
F
T
P
L
I
D
E
A
V
A
N
K
E
T
M
V
L
Q
T
V
E
----------
9
HHSearch
87.31
43%
-11
- C5 -
4KR6
3
THII_THEMA
A:
[3-387]
-
E
L
R
V
Y
I
V
R
Y
S
E
I
G
L
K
G
-
K
N
-
R
K
D
F
E
E
A
-
L
R
R
N
I
E
--
R
V
T
G
-
M
------
K
V
K
R
Q
W
G
R
F
L
I
P
I
D
E
--
N
V
T
L
D
D
K
L
K
K
I
F
G
I
Q
N
F
S
K
G
F
L
V
S
H
D
F
E
E
V
K
K
Y
S
L
----
I
A
V
K
E
K
L
E
K
--
G
N
----
Y
R
--
T
F
K
V
Q
A
K
K
A
Y
K
E
Y
K
K
G
V
Y
E
I
N
S
E
L
G
A
L
I
L
K
N
F
K
E
L
S
V
D
V
R
N
P
D
F
V
L
G
V
E
V
R
P
E
G
V
L
I
F
T
D
R
V
E
C
Y
G
G
L
P
V
G
T
G
G
K
A
V
L
L
L
S
G
G
I
D
S
P
V
A
G
W
Y
A
L
K
-
R
-----
G
-----
V
L
I
E
S
V
T
F
V
S
P
P
F
T
--
S
-
E
G
A
V
E
K
V
R
D
I
L
R
V
L
R
E
F
S
GG
H
P
--
L
-
R
-
L
H
I
V
N
--
L
T
K
L
Q
L
-
E
-----
V
----
K
-----
K
---
R
----
V
----
P
D
K
Y
S
L
I
M
Y
R
R
S
M
F
R
I
A
E
K
I
A
E
E
T
G
A
V
A
F
Y
T
G
E
N
I
G
Q
V
A
S
Q
T
L
E
N
---------
L
W
S
---------
I
E
S
---
V
T
T
R
P
V
I
R
P
L
S
--
G
--
F
-------
D
---
K
T
E
I
V
E
K
A
K
E
I
G
T
Y
E
I
--
S
I
K
P
Y
Q
D
S
C
V
F
-
F
A
P
K
N
P
A
T
R
S
H
P
S
I
L
E
K
L
E
Q
Q
V
P
D
L
P
V
L
E
E
E
A
F
T
S
R
K
V
E
V
I
--------------
5
PsiBlast_CBE
84.75
43%
-14
- C5 -
4KR7
1
THII_THEMA
B:
[8-376]
------
I
V
R
Y
S
E
I
G
L
K
G
-
K
N
-
R
K
D
F
E
E
A
-
L
R
R
N
I
E
--
R
V
----
T
G
M
---
K
V
K
R
Q
W
G
R
F
L
I
P
I
D
--
E
N
V
T
L
D
D
K
L
K
K
I
F
G
I
Q
N
F
S
K
G
F
L
V
S
H
D
F
E
E
V
K
K
Y
S
L
----
I
A
V
K
E
K
L
----
E
K
----
G
N
YR
T
F
K
V
Q
A
K
K
A
Y
K
E
Y
K
K
G
V
Y
E
I
N
S
E
L
G
A
L
I
L
K
N
F
K
E
L
S
V
D
V
R
N
P
D
F
V
L
G
V
E
V
R
P
E
G
V
L
I
F
T
D
R
V
E
C
Y
G
G
L
P
V
G
T
G
G
K
A
V
L
L
L
S
G
G
I
D
S
P
V
A
G
W
Y
A
L
K
-
R
-----
G
-----
V
L
I
E
S
V
T
F
V
S
P
P
F
T
--
S
-
E
G
A
V
E
K
V
R
D
I
L
R
V
L
R
E
F
S
--
G
G
HP
L
-
R
-
L
H
I
V
N
--
L
T
K
L
Q
L
-
E
-----
V
----
K
-----
K
---
R
----
V
----
P
D
K
Y
S
L
I
M
Y
R
R
S
M
F
R
I
A
E
K
I
A
E
E
T
G
A
V
A
F
Y
T
G
E
N
I
G
Q
V
A
S
Q
T
L
E
N
---------
L
W
S
---------
I
E
S
---
V
T
T
R
P
V
I
R
P
L
S
--
G
--
F
-------
D
---
K
T
E
I
V
E
K
A
K
E
I
G
T
Y
E
I
--
S
I
K
P
Y
Q
D
-
S
C
V
F
F
A
P
K
N
P
A
T
R
S
H
P
S
I
L
E
K
L
E
Q
Q
V
-
P
D
L
P
V
L
E
E
------------------------
6
PsiBlast_CBE
84.13
43%
-4
- C5 -
4KR6
1
THII_THEMA
B:
[8-376]
------
I
V
R
Y
S
E
I
G
L
K
G
-
K
N
-
R
K
D
F
E
E
A
-
L
R
R
N
I
E
--
R
V
----
T
G
M
---
K
V
K
R
Q
W
G
R
F
L
I
P
I
D
--
E
N
V
T
L
D
D
K
L
K
K
I
F
G
I
Q
N
F
S
K
G
F
L
V
S
H
D
F
E
E
V
K
K
Y
S
L
----
I
A
V
K
E
K
L
----
E
K
----
G
N
YR
T
F
K
V
Q
A
K
K
A
Y
K
E
Y
K
K
G
V
Y
E
I
N
S
E
L
G
A
L
I
L
K
N
F
K
E
L
S
V
D
V
R
N
P
D
F
V
L
G
V
E
V
R
P
E
G
V
L
I
F
T
D
R
V
E
C
Y
G
G
L
P
V
G
T
G
G
K
A
V
L
L
L
S
G
G
I
D
S
P
V
A
G
W
Y
A
L
K
-
R
-----
G
-----
V
L
I
E
S
V
T
F
V
S
P
P
F
T
--
S
-
E
G
A
V
E
K
V
R
D
I
L
R
V
L
R
E
F
S
--
G
G
HP
L
-
R
-
L
H
I
V
N
--
L
T
K
L
Q
L
-
E
-----
V
----
K
-----
K
---
R
----
V
----
P
D
K
Y
S
L
I
M
Y
R
R
S
M
F
R
I
A
E
K
I
A
E
E
T
G
A
V
A
F
Y
T
G
E
N
I
G
Q
V
A
S
Q
T
L
E
N
---------
L
W
S
---------
I
E
S
---
V
T
T
R
P
V
I
R
P
L
S
--
G
--
F
-------
D
---
K
T
E
I
V
E
K
A
K
E
I
G
T
Y
E
I
--
S
I
K
P
Y
Q
D
-
S
C
V
F
F
A
P
K
N
P
A
T
R
S
H
P
S
I
L
E
K
L
E
Q
Q
V
-
P
D
L
P
V
L
E
E
------------------------
3
PsiBlast_PDB
82.60
43%
-11
- C5 -
4KR9
-
THII_THEMA
A:
[8-376]
------
I
V
R
Y
S
E
I
G
L
K
G
-
K
N
-
R
K
D
F
E
E
A
-
L
R
R
N
I
E
--
R
V
----
T
G
M
---
K
V
K
R
Q
W
G
R
F
L
I
P
I
D
--
E
N
V
T
L
D
D
K
L
K
K
I
F
G
I
Q
N
F
S
K
G
F
L
V
S
H
D
F
E
E
V
K
K
Y
S
L
----
I
A
V
K
E
K
L
----
E
K
----
G
N
YR
T
F
K
V
Q
A
K
K
A
Y
K
E
Y
K
K
G
V
Y
E
I
N
S
E
L
G
A
L
I
L
K
N
F
K
E
L
S
V
D
V
R
N
P
D
F
V
L
G
V
E
V
R
P
E
G
V
L
I
F
T
D
R
V
E
C
Y
G
G
L
P
V
G
T
G
G
K
A
V
L
L
L
S
G
G
I
D
S
P
V
A
G
W
Y
A
L
K
-
R
-----
G
-----
V
L
I
E
S
V
T
F
V
S
P
P
F
T
--
S
-
E
G
A
V
E
K
V
R
D
I
L
R
V
L
R
E
F
S
--
G
G
H
P
L
-
R
-
L
H
I
V
N
--
L
T
K
L
Q
L
-
E
-----
V
----
K
-----
K
---
R
----
V
----
P
D
K
Y
S
L
I
M
Y
R
R
S
M
F
R
I
A
E
K
I
A
E
E
T
G
A
V
A
F
Y
T
G
E
N
I
G
Q
V
A
S
Q
T
L
E
N
---------
L
W
S
---------
I
E
S
---
V
T
T
R
P
V
I
R
P
L
S
--
G
--
F
-------
D
---
K
T
E
I
V
E
K
A
K
E
I
G
T
Y
E
I
--
S
I
K
P
Y
Q
D
-
S
C
V
F
F
A
P
K
N
P
A
T
R
S
H
P
S
I
L
E
K
L
E
Q
Q
V
-
P
D
L
P
V
L
E
E
------------------------
1
PsiBlast_PDB
82.47
43%
-7
* C5 *
4KR6
3
THII_THEMA
A:
[8-376]
------
I
V
R
Y
S
E
I
G
L
K
G
-
K
N
-
R
K
D
F
E
E
A
-
L
R
R
N
I
E
--
R
V
----
T
G
M
---
K
V
K
R
Q
W
G
R
F
L
I
P
I
D
--
E
N
V
T
L
D
D
K
L
K
K
I
F
G
I
Q
N
F
S
K
G
F
L
V
S
H
D
F
E
E
V
K
K
Y
S
L
----
I
A
V
K
E
K
L
----
E
K
----
G
N
YR
T
F
K
V
Q
A
K
K
A
Y
K
E
Y
K
K
G
V
Y
E
I
N
S
E
L
G
A
L
I
L
K
N
F
K
E
L
S
V
D
V
R
N
P
D
F
V
L
G
V
E
V
R
P
E
G
V
L
I
F
T
D
R
V
E
C
Y
G
G
L
P
V
G
T
G
G
K
A
V
L
L
L
S
G
G
I
D
S
P
V
A
G
W
Y
A
L
K
-
R
-----
G
-----
V
L
I
E
S
V
T
F
V
S
P
P
F
T
--
S
-
E
G
A
V
E
K
V
R
D
I
L
R
V
L
R
E
F
S
--
G
G
H
P
L
-
R
-
L
H
I
V
N
--
L
T
K
L
Q
L
-
E
-----
V
----
K
-----
K
---
R
----
V
----
P
D
K
Y
S
L
I
M
Y
R
R
S
M
F
R
I
A
E
K
I
A
E
E
T
G
A
V
A
F
Y
T
G
E
N
I
G
Q
V
A
S
Q
T
L
E
N
---------
L
W
S
---------
I
E
S
---
V
T
T
R
P
V
I
R
P
L
S
--
G
--
F
-------
D
---
K
T
E
I
V
E
K
A
K
E
I
G
T
Y
E
I
--
S
I
K
P
Y
Q
D
-
S
C
V
F
F
A
P
K
N
P
A
T
R
S
H
P
S
I
L
E
K
L
E
Q
Q
V
-
P
D
L
P
V
L
E
E
------------------------
2
PsiBlast_PDB
81.01
43%
-10
- C5 -
4KR7
1
THII_THEMA
A:
[8-376]
------
I
V
R
Y
S
E
I
G
L
K
G
-
K
N
-
R
K
D
F
E
E
A
-
L
R
R
N
I
E
--
R
V
----
T
G
M
---
K
V
K
R
Q
W
G
R
F
L
I
P
I
D
--
E
N
V
T
L
D
D
K
L
K
K
I
F
G
I
Q
N
F
S
K
G
F
L
V
S
H
D
F
E
E
V
K
K
Y
S
L
----
I
A
V
K
E
K
L
----
E
K
----
G
N
YR
T
F
K
V
Q
A
K
K
A
Y
K
E
Y
K
K
G
V
Y
E
I
N
S
E
L
G
A
L
I
L
K
N
F
K
E
L
S
V
D
V
R
N
P
D
F
V
L
G
V
E
V
R
P
E
G
V
L
I
F
T
D
R
V
E
C
Y
G
G
L
P
V
G
T
G
G
K
A
V
L
L
L
S
G
G
I
D
S
P
V
A
G
W
Y
A
L
K
-
R
-----
G
-----
V
L
I
E
S
V
T
F
V
S
P
P
F
T
--
S
-
E
G
A
V
E
K
V
R
D
I
L
R
V
L
R
E
F
S
--
G
G
H
P
L
-
R
-
L
H
I
V
N
--
L
T
K
L
Q
L
-
E
-----
V
----
K
-----
K
---
R
----
V
----
P
D
K
Y
S
L
I
M
Y
R
R
S
M
F
R
I
A
E
K
I
A
E
E
T
G
A
V
A
F
Y
T
G
E
N
I
G
Q
V
A
S
Q
T
L
E
N
---------
L
W
S
---------
I
E
S
---
V
T
T
R
P
V
I
R
P
L
S
--
G
--
F
-------
D
---
K
T
E
I
V
E
K
A
K
E
I
G
T
Y
E
I
--
S
I
K
P
Y
Q
D
-
S
C
V
F
F
A
P
K
N
P
A
T
R
S
H
P
S
I
L
E
K
L
E
Q
Q
V
-
P
D
L
P
V
L
E
E
------------------------
10
HHSearch
64.99
29%
12
- C5 -
1VBK
2
?
A:
[1-307]
--
M
N
V
V
I
V
R
Y
G
E
I
G
T
K
S
R
Q
T
-
R
S
W
F
E
K
I
-
L
M
N
N
I
R
--
E
A
L
V
T
E
-
E
V
PYK
E
I
F
S
R
H
G
R
I
I
V
K
T
N
S
--
P
K
E
A
A
N
V
L
V
R
V
F
G
I
V
S
I
S
P
A
M
E
V
E
A
S
L
E
K
I
N
R
T
A
L
----
L
M
F
R
K
K
A
K
E
V
G
K
E
----
R
P
--
K
F
R
V
T
A
R
R
I
T
K
E
F
P
L
D
S
L
E
I
Q
A
K
V
G
E
Y
I
L
N
N
E
-
N
C
E
V
D
L
K
N
Y
D
I
E
I
G
I
E
I
M
Q
G
K
A
Y
I
Y
T
E
K
I
K
G
W
G
G
L
P
I
G
T
E
G
R
M
I
G
I
L
H
D
E
-
L
S
A
L
A
I
F
L
M
M
K
-
R
-----
G
-----
V
E
V
I
P
V
Y
I
G
K
D
-------
D
K
N
L
E
K
V
R
S
L
W
N
L
L
-------
K
--
R
-
Y
-
S
Y
--
G
--
S
K
G
F
--------------------------------------
L
V
V
A
---
E
S
F
D
R
V
L
K
L
I
R
D
F
G
V
K
G
V
I
K
G
L
R
P
N
D
L
N
S
E
V
S
E
----------
I
T
E
---------
D
F
K
---
M
F
P
V
P
V
Y
Y
P
L
I
--
A
--
L
-------
P
---
E
E
Y
I
K
S
V
K
E
R
L
G
L
------------------------------------------------------------------------
31
Fugue
60.72
27%
20
- C5 -
1VBK
2
?
A:
[1-307]
--
M
N
V
V
I
V
R
Y
G
E
I
G
T
K
S
-
R
Q
T
R
S
W
F
E
K
I
-
L
M
N
N
I
R
--
E
A
L
V
T
E
E
V
P
---
Y
K
E
I
F
S
R
H
G
R
I
I
V
K
T
N
S
P
K
E
A
A
N
V
L
V
R
V
F
G
I
V
S
I
S
P
A
M
E
V
E
A
S
L
E
K
I
N
R
T
A
L
----
L
M
F
R
K
K
A
----
K
E
V
GKE
R
P
--
K
F
R
V
T
A
R
R
I
T
K
E
F
P
L
D
S
L
E
I
Q
A
K
V
G
E
Y
I
L
N
N
E
-
N
C
E
V
D
L
K
N
Y
D
I
E
I
G
I
E
I
M
Q
G
K
A
Y
I
Y
T
E
K
I
K
G
W
G
G
L
P
I
G
T
E
G
R
M
I
G
I
L
H
D
E
L
-
S
A
L
A
I
F
L
M
M
K
-
R
-----
G
-----
V
E
V
I
P
V
Y
I
----
G
K
--
D
-
D
K
N
L
E
K
V
R
S
L
W
N
L
L
K
R
Y
S
--
Y
G
--
S
-
K
-
G
F
L
--------------------------------------------------
V
V
A
E
S
F
D
R
V
L
K
L
I
R
D
F
G
V
K
G
V
I
K
G
L
R
P
N
D
L
N
S
E
V
S
E
I
---------
T
E
D
---------
F
K
M
---
F
-
P
V
P
V
Y
Y
P
L
I
--
A
--
L
-------
P
---
E
E
Y
I
K
S
V
K
E
R
L
G
L
------------------------------------------------------------------------
4
PsiBlast_PDB
54.73
33%
-16
- C5 -
1VBK
2
?
A:
[4-252]
-----
V
I
V
R
Y
G
E
I
G
T
K
S
-
R
Q
-
T
R
S
W
F
E
K
I
L
M
N
N
I
R
E
A
L
V
T
E
E
V
P
Y
K
---
E
I
F
S
R
H
G
R
I
I
V
K
T
N
--
S
P
K
E
A
A
N
V
L
V
R
V
F
G
I
V
S
I
S
P
A
M
E
V
E
A
S
L
E
K
I
N
R
T
A
L
L
M
F
R
K
K
A
K
E
V
G
----
K
E
----
R
P
--
K
F
R
V
T
A
R
R
I
T
K
E
F
P
L
D
S
L
E
I
Q
A
K
V
G
E
Y
I
L
-
N
N
E
N
C
E
V
D
L
K
N
Y
D
I
E
I
G
I
E
I
M
Q
G
K
A
Y
I
Y
T
E
K
I
K
G
W
G
G
L
P
I
G
T
E
G
R
M
I
G
I
L
H
D
E
L
-
S
A
L
A
I
F
L
M
M
K
-
R
-----
G
-----
V
E
V
I
P
V
Y
I
G
K
------
D
-
D
K
N
L
E
K
V
R
S
L
W
N
L
L
K
R
Y
S
Y-
G
S
--
K
-
G
-
F
L
V
V
A
ES
F
D
R
V
L
K
-
L
-----
I
----
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_CBE
51.59
33%
-16
- C5 -
1VBK
2
?
B:
[4-258]
-----
V
I
V
R
Y
-----
K
S
-
R
Q
-
T
R
S
W
F
E
K
I
L
M
N
N
I
R
E
A
L
V
T
E
E
V
P
Y
K
---
E
I
F
S
R
H
G
R
I
I
V
K
T
N
--
S
P
K
E
A
A
N
V
L
V
R
V
F
G
I
V
S
I
S
P
A
M
E
V
E
A
S
L
E
K
I
N
R
T
A
L
L
M
F
R
K
K
A
K
E
V
G
----
K
E
----
R
P
--
K
F
R
V
T
A
R
R
I
T
K
E
F
P
L
D
S
L
E
I
Q
A
K
V
G
E
Y
I
L
-
N
N
E
N
C
E
V
D
L
K
N
Y
D
I
E
I
G
I
E
I
M
Q
G
K
A
Y
I
Y
T
E
K
I
K
G
W
G
G
L
P
I
G
T
E
G
R
M
I
G
I
L
H
D
E
L
-
S
A
L
A
I
F
L
M
M
K
-
R
-----
G
-----
V
E
V
I
P
V
Y
I
G
K
------
D
-
D
K
N
L
E
K
V
R
S
L
W
N
L
L
K
R
Y
S
Y-
G
S
--
K
-
G
-
F
L
V
V
A
ES
F
D
R
V
L
K
-
L
-----
I
----
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
46.40
13%
-16
- C5 -
2NZ2
3
ASSY_HUMAN
A:
[5-174]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
G
S
V
V
L
A
Y
S
G
G
L
D
T
S
C
I
L
V
W
L
K
E
-
Q
-----
G
-----
Y
D
V
I
A
Y
L
A
N
I
G
Q
K
------
E
D
F
E
E
A
R
K
K
A
L
K
L
-------
G
--
A
-
K
K
V
F
I
E
D
--
V
S
R
E
F
V
-
E
E----
F
----
I
W
P
A
I
Q
S
---
S
----
A
LYED
R
Y
L
L
G
T
S
L
A
R
P
C
I
A
R
K
Q
V
E
I
A
Q
R
E
G
A
K
Y
V
S
H
G
A
T
G
K
G
N
-
D
Q
V
R
F
E
---------
L
S
----------
C
Y
S
L
--
A
P
Q
I
K
V
I
A
P
W
R
MP
E
--
F
YNRFK------
R
N
D
L
M
E
Y
A
K
Q
H
G
I
P
I
P
---------------------------------------------------------------------
24
HHSearch
46.17
18%
-23
- C5 -
3A2K
-
TILS_GEOKA
A:
[17-187]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
G
A
A
V
I
V
G
V
S
G
G
P
D
S
L
A
L
L
H
V
F
L
S
-
L
R
D
E
W
-
K
-----
L
Q
V
I
A
A
H
V
D
H
M
F
R
G
R
E
S
-
E
E
E
M
E
F
V
K
R
F
C
V
E
R
-------
R
--
I
-
L
-
C
E
T
A
Q
--
I
D
V
P
A
--------
F
----
Q
---------
R
----
S
----
A
G
L
G
A
Q
E
A
A
R
I
C
R
Y
R
F
F
A
E
L
M
E
K
H
Q
A
G
Y
V
A
V
G
H
H
G
D
D
Q
V
E
T
I
L
M
R
---------
L
V
R
GSTSKGYAG
I
P
V
KRP
F
H
G
G
Y
L
I
R
P
F
L
--
A
--
V
-------
S
---
R
A
E
I
E
A
Y
C
R
Q
M
G
L
S
P
R
---------------------------------------------------------------------
23
HHSearch
46.05
18%
-28
- C5 -
1NI5
-
TILS_ECOLI
A:
[11-175]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
S
R
Q
I
L
V
A
F
S
G
G
L
D
S
T
V
L
L
H
Q
L
V
Q
-
W
R
T
E
N
P
G
-----
V
A
L
R
A
I
H
V
H
H
G
L
S
A
--
N
A
D
A
W
V
T
H
C
E
N
V
C
Q
Q
W
-------
Q
--
V
-
P
-
L
V
V
E
R
--
V
Q
L
A
Q
---------------------------------
E
G
L
G
I
E
A
Q
A
R
Q
A
R
Y
Q
A
F
A
R
T
L
L
--
P
G
E
V
L
V
T
A
Q
H
L
D
D
Q
C
E
T
F
L
L
A
L
K
R
GSGPAG
L
S
A
---------
M
A
E
V
S
E
F
A
G
T
R
L
I
R
P
L
L
--
A
--
R
-------
T
---
R
G
E
L
V
Q
W
A
R
Q
Y
D
L
R
W
I
---------------------------------------------------------------------
22
HHSearch
45.69
16%
4
- C5 -
4XFJ
4
?
A:
[10-177]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
E
R
V
I
L
A
Y
S
G
G
L
D
T
S
V
A
I
S
W
I
G
K
E
T
-----
G
-----
R
E
V
V
A
V
A
I
D
L
G
Q
G
G
-----
E
D
M
E
V
V
R
Q
R
A
L
D
C
-------
G
--
A
V
E
-
S
I
V
I
D
--
A
R
D
E
F
A
N
D
Y
C
V
P
A
I
----
Q
-----
S
---
N
A
L
Y
M
D
----
R
Y
P
L
V
S
A
L
S
R
P
L
I
V
K
H
L
V
K
A
A
R
E
H
G
G
T
I
V
A
H
G
C
T
G
K
G
-
N
D
Q
V
R
-
F
---------
E
V
G
---------
F
A
S
L
--
A
P
D
L
E
V
L
A
P
V
R
--
D
YA
W
-------
T
---
R
E
K
A
I
A
F
A
E
E
N
N
I
P
I
N
---------------------------------------------------------------------
13
HHSearch
45.55
22%
7
- C5 -
1WY5
-
TILS_AQUAE
A:
[23-190]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
E
R
R
V
L
I
A
F
S
G
G
V
D
S
V
V
L
T
D
V
L
L
K
-
L
-----
K
NYFSL
K
E
V
A
L
A
H
F
N
H
M
L
R
E
--
S
A
E
R
D
E
E
F
C
K
E
F
A
K
E
R
-------
N
--
M
-
K
-
I
F
V
G
K
--
E
D
V
R
A
--------
F
----
A
-----
K
--------
E
----
N
R
M
S
L
E
E
A
G
R
F
L
R
Y
K
F
L
K
E
I
L
E
S
E
G
F
D
C
I
A
T
A
H
H
L
N
D
L
L
E
T
S
L
L
F
---------
F
T
R
GTG
L
D
G
---
L
I
G
FL-
P
K
E
E
V
I
R
R
P
L
Y
--
Y
--
V
-------
K
---
R
S
E
I
E
E
Y
A
K
F
K
G
L
R
W
V
--
E
------------------------------------------------------------------
26
HHSearch
45.33
15%
-10
- C5 -
1KOR
3
ASSY_THET8
A:
[2-180]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
V
L
A
Y
S
G
G
L
D
T
S
I
I
L
K
W
L
K
E
-
T
Y
----
R
-----
A
E
V
I
A
F
T
A
D
I
G
Q
G
------
E
E
V
E
E
A
R
E
K
A
L
R
T
-------
G
--
A
-
S
K
A
I
A
L
D
--
L
K
E
E
F
V
R
D
-----
F
V
F
P
M
M
-----
R
A
--
G
AVYE
G
----
Y
Y
L
L
G
T
S
I
A
R
P
L
I
A
K
H
L
V
R
I
A
E
E
E
G
A
E
A
I
A
H
G
A
T
G
K
G
-
N
D
Q
V
R
F
E
---------
L
T
A
---------
Y
A
L
---
K
P
D
I
K
V
I
A
P
W
R
--
E
--
W
-------
S
FQG
R
K
E
M
I
A
Y
A
E
A
H
G
I
P
V
P
---------------------------------------------------------------------
14
HHSearch
44.61
16%
-19
- C5 -
1VL2
-
ASSY_THEMA
A:
[2-178]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
K
V
V
L
A
Y
S
G
G
L
D
T
S
V
I
L
K
W
L
C
E
-
K
-----
G
-----
F
D
V
I
A
Y
V
A
N
V
G
Q
K
------
D
D
F
V
A
I
K
E
K
A
L
K
T
-------
G
--
A
S
K
-
V
Y
V
E
D
--
L
R
R
E
F
V
T
D
Y
I
F
T
A
L
----
L
-----
G
---
N
AMYE
G
----
R
Y
L
L
G
T
A
I
A
R
P
L
I
A
K
R
Q
V
E
I
A
E
K
E
G
A
Q
Y
V
A
H
G
A
T
G
K
G
N
-
D
Q
V
R
-
F
---------
E
L
T
---------
Y
A
A
L
--
N
P
N
L
K
V
I
S
P
W
K
--
D
--
P
E
F
L
A
K
F
K-----
T
D
L
I
N
Y
A
M
E
K
G
I
P
I
K
---------------------------------------------------------------------
27
HHSearch
43.79
13%
-33
- C5 -
2O8V
-
CYSH_ECOLI
A:
[46-216]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
E
Y
V
L
S
S
S
F
G
I
Q
A
A
V
S
L
H
L
V
N
Q
-
I
-----
R
-----
P
D
I
P
V
I
L
T
D
T
G
Y
L
F
----
P
E
T
Y
R
F
I
D
E
L
T
D
K
L
-------
K
--
L
-
N
-
L
K
V
Y
R
--
A
T
E
S
A
A
-
W
-----
Q
E
A
R
-
Y
-----
G
KLW
E
----
Q
----
G
V
E
G
I
E
K
Y
N
D
I
N
K
V
E
P
M
N
R
A
L
K
E
L
N
A
Q
T
W
F
A
G
L
R
R
E
Q
S
G
S
R
--
A
N
---------
L
P
V
---------
L
A
I
---
Q
R
G
V
F
K
V
L
P
I
I
--
D
--
W
-------
D
---
N
R
T
I
Y
Q
Y
L
Q
K
H
G
L
K
Y
H
---------------------------------------------------------------------
12
HHSearch
43.27
14%
19
- C5 -
3TQI
-
GUAA_COXBU
A:
[228-445]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Q
V
I
V
G
L
S
G
G
V
D
S
A
V
T
A
T
L
V
H
K
-
A
I----
G
-----
D
Q
L
V
C
V
L
V
D
T
G
L
L
R
--
L
-
N
E
V
D
E
V
L
N
V
F
Q
K
H
L
-------
G
--
A
-
K
-
V
I
C
V
D
--
A
K
D
R
F
M
-
K
A----
L
----
K
-----
G
---
I
----
S
----
D
P
E
E
K
R
K
I
A
G
E
Q
F
I
R
V
F
E
E
Q
A
K
K
L
N
V
K
W
L
G
Q
G
T
I
Y
P
D
V
I
E
S
-----------------------------------
K
L
I
E
P
L
R
--
E
--
L
-------
F
---
K
D
E
V
R
K
L
G
L
E
L
G
L
P
A
D
L
I
Y
R
H
P
F
P
G
P
G
L
A
I
R
I
L
-
G
E
V
S
A
E
Y
I
N
I
L
K
Q
A
D
A
I
F
---------------------------------