@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu30280: (2016-07-19 )
MSEIARDVHVKQVKPKKQSSLWWMYIPALLSVLVFMIYPFVKGTLITFTNWNGFSQVYQWVGFAQYERLFSDPDTWHILKNTLHYGLGSTFFQNVVGLLYALLLNQSIKTKAVTRTIVYLPVMISPLIMGYIWYFFFSYDGGALNDLLGVFGISPINALASPSLNPWIIVMINTYQYVGIAMVVYLAGLQSIPKDYYEAAQMDGAKQGQQFFTITLPLLMPSITINIVINIIGGLKLFDVIIALTAGGPGNASQSMSTFMYDLYFKRQDAGYAATQGIFMAFVILIISFCALAYFKRKETEMS
Atome Classification :
(20 SA)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10........20........30........40--........50........60........70...----...----..80........90........100...-.--.-..110.......120.......130.......140......-.150........160.......170.......180..--.....190.......200.......210.......220.......230.....-..240.......---250-------........260.-----...---...270.......280.......290........300.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
S
E
I
A
R
DVH
V
K
QVKPKKQS
S
L
W
W
M
Y
I
P
A
L
L
S
V
L
V
F
M
I
Y
P
FV--K
G
T
L
I
T
F
TNWN
G
F
S
Q
V
Y
Q
W
V
G
F
A
Q
Y
E
R
L
FSDP
D
----
T
W
H
----
I
L
K
N
T
L
H
YG
L
G
S
T
F
F
Q
N
V
V
G
L
L
Y
A
L
L
LN-Q--S-IKTK
A
V
T
R
T
I
V
Y
L
P
V
M
I
S
P
L
I
M
G
Y
I
W
Y
F
F
F
SYDG
G
A
L
N
D
L
L
-
G
V
F-GIS
P
I
N
A
LASPSLN
P
W
I
I
V
M
INT
Y
Q
Y
V
G
I
A
M
V
V
--
Y
L
A
G
L
Q
SI
P
K
D
Y
Y
E
A
A
QMDGAKQG
Q
Q
F
F
T
I
T
L
P
LLMP
S
I
T
I
N
I
V
I
NIIG
G
L
K
L
-
F
D
V
I
I
A
L
TAGGP---GN--------
A
S
Q
S
M
S
T
F
M
Y
D
L
-----
Y
F
K---RQDAG
Y
A
A
T
Q
G
I
F
M
A
F
V
I
L
I
I
S
F
C
-
A
L
A
Y
F
K
RKETEMS
2
PsiBlast_PDB
79.72
29%
-114
- C2 -
4TQV
-
?
A:
[32-320]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
R
D
W
L
L
Y
A
M
L
L
P
T
I
I
W
F
L
I
F
L
Y
K
P
M
I
G
L
Q
M
A
F
K
Q
-----------
P
W
I
G
F
D
H
F
V
T
L
F
Q
S
E
Q
----
F
I
R
----
A
I
K
N
T
L
T
L
S
G
L
S
L
L
F
G
F
P
M
P
I
L
L
A
L
M
I
N
-
E
VY
S
-
K
G
Y
R
K
A
V
Q
T
I
V
Y
L
P
H
F
I
S
I
V
I
V
A
G
L
V
V
T
F
L
S
P
S
T
G
V
V
N
N
M
L
-
S
W
I
-
G
L
D
R
V
Y
F
L
T
Q
P
E
W
F
R
P
I
Y
I
S
S
N
I
W
K
E
A
G
F
D
S
I
V
--
Y
L
A
A
I
M
S
I
N
P
A
L
Y
E
S
A
Q
V
D
G
A
T
R
W
Q
M
I
T
R
I
T
L
P
C
I
V
P
T
I
A
V
L
L
V
I
R
L
G
H
I
L
E
V
G
F
E
Y
I
I
L
L
Y
Q
P
T
T
---
Y
E
--------
T
A
D
V
I
S
T
Y
I
Y
R
L
-----
G
L
Q
---
G
A
R
Y
D
I
A
T
A
A
G
I
F
N
A
V
V
A
L
V
I
V
L
F
-
A
-
N
H
M
S
R
R
I
T
K
--
31
HHSearch
79.68
30%
-119
- C2 -
4TQU
-
?
M:
[5-297]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
K
D
I
K
R
D
W
L
L
Y
A
M
L
L
P
T
I
I
W
F
L
I
F
L
Y
K
P
M
I
--
G
-
L
Q
M
A
F
----------
P
W
I
G
F
D
H
F
V
T
L
F
Q
S
E
Q
----
F
I
R
----
A
I
K
N
T
L
T
L
S
G
L
S
L
L
F
G
F
P
M
P
I
L
L
A
L
M
I
N
-
E
V-
Y
S
K
G
Y
R
K
A
V
Q
T
I
V
Y
L
P
H
F
I
S
I
V
I
V
A
G
L
V
V
T
F
L
S
P
S
T
G
V
V
N
N
M
L
-
S
W
I
-
G
L
D
R
V
Y
F
L
T
Q
P
E
W
F
R
P
I
Y
I
S
S
N
I
W
K
E
A
G
F
D
S
I
V
--
Y
L
A
A
I
M
S
I
N
P
A
L
Y
E
S
A
Q
V
D
G
A
T
R
W
Q
M
I
T
R
I
T
L
P
C
I
V
P
T
I
A
V
L
L
V
I
R
L
G
H
I
L
E
V
G
F
E
Y
I
I
L
L
--
Y
Q
P
---
T
T
YE------
T
A
D
V
I
S
T
Y
I
Y
R
L
-----
G
L
Q
---
G
A
R
Y
D
I
A
T
A
A
G
I
F
N
A
V
V
A
L
V
I
V
L
F
-
A
N
H
M
S
R
R
I
T
K
---
1
PsiBlast_PDB
77.42
29%
-114
- C2 -
4TQU
-
?
M:
[9-297]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
R
D
W
L
L
Y
A
M
L
L
P
T
I
I
W
F
L
I
F
L
Y
K
P
M
I
GL
Q
M
A
F
-------------
P
W
I
G
F
D
H
F
V
T
L
F
Q
S
E
Q
----
F
I
R
----
A
I
K
N
T
L
T
L
S
G
L
S
L
L
F
G
F
P
M
P
I
L
L
A
L
M
I
N
-
E
VY
S
-
K
G
Y
R
K
A
V
Q
T
I
V
Y
L
P
H
F
I
S
I
V
I
V
A
G
L
V
V
T
F
L
S
P
S
T
G
V
V
N
N
M
L
-
S
W
I
-
G
L
D
R
V
Y
F
L
T
Q
P
E
W
F
R
P
I
Y
I
S
S
N
I
W
K
E
A
G
F
D
S
I
V
--
Y
L
A
A
I
M
S
I
N
P
A
L
Y
E
S
A
Q
V
D
G
A
T
R
W
Q
M
I
T
R
I
T
L
P
C
I
V
P
T
I
A
V
L
L
V
I
R
L
G
H
I
L
E
V
G
F
E
Y
I
I
L
L
Y
Q
P
T
T
---
Y
E
--------
T
A
D
V
I
S
T
Y
I
Y
R
L
-----
G
L
Q
---
G
A
R
Y
D
I
A
T
A
A
G
I
F
N
A
V
V
A
L
V
I
V
L
F
-
A
-
N
H
M
S
R
R
I
T
K
--
3
PsiBlast_PDB
76.79
29%
-107
- C2 -
4XIG
-
?
M:
[9-297]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
R
D
W
L
L
Y
A
M
L
L
P
T
I
I
W
F
L
I
F
L
Y
K
P
M
I
GL
Q
M
A
F
K
Q
Y
------------
I
G
F
D
H
F
V
T
L
F
Q
S
E
Q
----
F
I
R
----
A
I
K
N
T
L
T
L
S
G
L
S
L
L
F
G
F
P
M
P
I
L
L
A
L
M
I
N
-
E
VY
S
-
K
G
Y
R
K
A
V
Q
T
I
V
Y
L
P
H
F
I
S
I
V
I
V
A
G
L
V
V
T
F
L
S
P
S
T
G
V
V
N
N
M
L
-
S
W
I
-
G
L
D
R
V
Y
F
L
T
Q
P
E
W
F
R
P
I
Y
I
S
S
N
I
W
K
E
A
G
F
D
S
I
V
--
Y
L
A
A
I
M
S
I
N
P
A
L
Y
E
S
A
Q
V
D
G
A
T
R
W
Q
M
I
T
R
I
T
L
P
C
I
V
P
T
I
A
V
L
L
V
I
R
L
G
H
I
L
E
V
G
F
E
Y
I
I
L
L
Y
Q
P
T
T
---
Y
E
--------
T
A
D
V
I
S
T
Y
I
Y
R
L
-----
G
L
Q
---
G
A
R
Y
D
I
A
T
A
A
G
I
F
N
A
V
V
A
L
V
I
V
L
F
-
A
-
N
H
M
S
R
R
I
T
K
--
4
PsiBlast_PDB
75.76
29%
-115
- C2 -
4XTC
-
?
M:
[9-297]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
R
D
W
L
L
Y
A
M
L
L
P
T
I
I
W
F
L
I
F
L
Y
K
P
M
I
GL
Q
M
A
F
K
Q
Y
------------
I
G
F
D
H
F
V
T
L
F
Q
S
E
Q
----
F
I
R
----
A
I
K
N
T
L
T
L
S
G
L
S
L
L
F
G
F
P
M
P
I
L
L
A
L
M
I
N
-
E
VY
S
-
K
G
Y
R
K
A
V
Q
T
I
V
Y
L
P
H
F
I
S
I
V
I
V
A
G
L
V
V
T
F
L
S
P
S
T
G
V
V
N
N
M
L
-
S
W
I
-
G
L
D
R
V
Y
F
L
T
Q
P
E
W
F
R
P
I
Y
I
S
S
N
I
W
K
E
A
G
F
D
S
I
V
--
Y
L
A
A
I
M
S
I
N
P
A
L
Y
E
S
A
Q
V
D
G
A
T
R
W
Q
M
I
T
R
I
T
L
P
C
I
V
P
T
I
A
V
L
L
V
I
R
L
G
H
I
L
E
V
G
F
E
Y
I
I
L
L
Y
Q
P
T
T
---
Y
E
--------
T
A
D
V
I
S
T
Y
I
Y
R
L
-----
G
L
Q
---
G
A
R
Y
D
I
A
T
A
A
G
I
F
N
A
V
V
A
L
V
I
V
L
F
-
A
-
N
H
M
S
R
R
I
T
K
--
13
PsiBlast_PDB
71.23
28%
-83
- C2 -
4JBW
1
MALF_ECOLI
F:
[259-509]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
W
K
N
F
T
R
V
F
T
D
E
G
----
I
Q
K
PFLA
I
F
V
W
T
V
V
F
S
L
I
T
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
W
E
--
A
-
L
R
G
K
A
V
Y
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
F
K
G
L
F
N
Q
S
F
G
E
I
N
M
M
L
S
A
L
F
-
G
V
K
P
A
-
W
F
S
D
P
T
T
A
R
T
M
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
--
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
M
I
A
S
F
A
F
N
F
N
N
-
F
V
L
I
Q
L
L
T
N
G
G
P
---
D
R
--------
L
G
T
T
T
P
A
G
Y
T
D
L
LVNYT
Y
R
I
---
A
F
E
G
G
G
G
Q
D
F
G
L
A
A
A
I
A
T
L
I
F
L
L
V
G
A
L
A
I
V
N
L
K
A
T
---
21
Fugue
70.96
22%
-125
- C2 -
2R6G
1
MALF_ECOLI
F:
[13-504]
DALKWSVLGLLGLLVGYLVVLMYAQGEYLFAITTLILSSAGLYIFANRKAYAWRYVYPGMAGMGLFVLFPLVCTIAIAFTNYSSTNQLTFERAQEVLLDRSWQAGKTYNFGLYPAGDEWQLALSDGETGKNYLSDAFKFGGEQKLQLKETTAQPEGERANLRVITQNRQALSDITAILPDGNKV
M
M
S
S
L
R
Q
F
S
G
T
Q
P
L
Y
T
L
D
G
D
G
T
L
T
N
N
Q
S
G
V
K
Y
R
P
N
N
Q
I
G
F
Y
--
Q
S
I
T
A
N
W
G
D
E
K
L
S
P
G
Y
T
V
T
T
G
W
K
N
F
T
R
V
F
T
D
E
G
IQKP
F
L
A
----
I
F
V
W
T
V
V
F
S
L
I
T
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
-
W
E-
A
-
L
R
G
K
A
V
Y
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
F
K
G
L
F
N
Q
S
F
G
E
I
N
M
M
L
-
S
A
L
-
F
G
V
K
P
A
W
F
S
D
P
T
T
A
R
T
M
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
--
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
M
I
A
S
F
A
F
N
F
N
N
-
F
V
L
I
Q
L
L
T
N
G
G
P
DRL
G
T
--------
T
T
P
A
G
Y
T
D
L
L
V
N
-----
Y
T
Y
---
R
I
A
F
E
G
G
G
G
Q
D
F
G
L
A
A
A
I
A
T
L
I
F
L
-
L
V
G
A
L
A
I
V
-----
35
HHSearch
70.28
28%
-95
- C2 -
3RLF
2
MALF_ECOLI
F:
[258-503]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
T
G
W
K
N
F
T
R
V
F
T
D
E
G
IQKP
F
L
A
----
I
F
V
W
T
V
V
F
S
L
I
T
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
-
W
E-
A
-
L
R
G
K
A
V
Y
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
F
K
G
L
F
N
Q
S
F
G
E
I
N
M
M
L
-
S
A
L
F
G
V
-
K
P
A
W
F
S
D
P
T
T
A
R
T
M
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
--
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
M
I
A
S
F
A
F
N
F
N
N
-
F
V
L
I
Q
L
L
T
N
G
G
P
---
D
R
LGTTTPAG
Y
T
D
L
L
V
N
Y
T
Y
R
I
-----
A
F
E
GGG
G
Q
D
F
G
L
A
A
A
I
A
T
L
I
F
L
L
V
G
A
L
A
I
---------------
8
PsiBlast_PDB
68.30
28%
-78
- C2 -
3PV0
2
MALF_ECOLI
F:
[259-505]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
W
K
N
F
T
R
V
F
T
D
E
G
----
I
Q
K
PFLA
I
F
V
W
T
V
V
F
S
L
I
T
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
W
E
--
A
-
L
R
G
K
A
V
Y
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
F
K
G
L
F
N
Q
S
F
G
E
I
N
M
M
L
S
A
L
F
-
G
V
K
P
A
-
W
F
S
D
P
T
T
A
R
T
M
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
--
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
M
I
A
S
F
A
F
N
F
N
N
-
F
V
L
I
Q
L
L
T
N
G
G
P
---
D
R
--------
L
G
T
T
T
P
A
G
Y
T
D
L
LVNYT
Y
R
I
---
A
F
E
G
G
G
G
Q
D
F
G
L
A
A
A
I
A
T
L
I
F
L
L
V
G
A
L
A
I
V
N
-------
14
PsiBlast_PDB
68.10
28%
-83
- C2 -
4KHZ
2
MALF_ECOLI
F:
[259-505]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
W
K
N
F
T
R
V
F
T
D
E
G
----
I
Q
K
PFLA
I
F
V
W
T
V
V
F
S
L
I
T
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
W
E
--
A
-
L
R
G
K
A
V
Y
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
F
K
G
L
F
N
Q
S
F
G
E
I
N
M
M
L
S
A
L
F
-
G
V
K
P
A
-
W
F
S
D
P
T
T
A
R
T
M
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
--
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
M
I
A
S
F
A
F
N
F
N
N
-
F
V
L
I
Q
L
L
T
N
G
G
P
---
D
R
--------
L
G
T
T
T
P
A
G
Y
T
D
L
LVNYT
Y
R
I
---
A
F
E
G
G
G
G
Q
D
F
G
L
A
A
A
I
A
T
L
I
F
L
L
V
G
A
L
A
I
V
N
-------
15
PsiBlast_PDB
68.06
28%
-88
- C2 -
4KI0
5
MALF_ECOLI
F:
[259-505]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
W
K
N
F
T
R
V
F
T
D
E
G
----
I
Q
K
PFLA
I
F
V
W
T
V
V
F
S
L
I
T
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
W
E
--
A
-
L
R
G
K
A
V
Y
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
F
K
G
L
F
N
Q
S
F
G
E
I
N
M
M
L
S
A
L
F
-
G
V
K
P
A
-
W
F
S
D
P
T
T
A
R
T
M
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
--
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
M
I
A
S
F
A
F
N
F
N
N
-
F
V
L
I
Q
L
L
T
N
G
G
P
---
D
R
--------
L
G
T
T
T
P
A
G
Y
T
D
L
LVNYT
Y
R
I
---
A
F
E
G
G
G
G
Q
D
F
G
L
A
A
A
I
A
T
L
I
F
L
L
V
G
A
L
A
I
V
N
-------
5
PsiBlast_PDB
67.65
28%
-85
- C2 -
2R6G
1
MALF_ECOLI
F:
[259-504]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
W
K
N
F
T
R
V
F
T
D
E
G
----
I
Q
K
PFLA
I
F
V
W
T
V
V
F
S
L
I
T
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
W
E
--
A
-
L
R
G
K
A
V
Y
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
F
K
G
L
F
N
Q
S
F
G
E
I
N
M
M
L
S
A
L
F
-
G
V
K
P
A
-
W
F
S
D
P
T
T
A
R
T
M
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
--
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
M
I
A
S
F
A
F
N
F
N
N
-
F
V
L
I
Q
L
L
T
N
G
G
P
---
D
R
--------
L
G
T
T
T
P
A
G
Y
T
D
L
LVNYT
Y
R
I
---
A
F
E
G
G
G
G
Q
D
F
G
L
A
A
A
I
A
T
L
I
F
L
L
V
G
A
L
A
I
V
--------
11
PsiBlast_PDB
67.47
28%
-94
- C2 -
3PUX
3
MALF_ECOLI
F:
[259-503]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
W
K
N
F
T
R
V
F
T
D
E
G
----
I
Q
K
PFLA
I
F
V
W
T
V
V
F
S
L
I
T
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
W
E
--
A
-
L
R
G
K
A
V
Y
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
F
K
G
L
F
N
Q
S
F
G
E
I
N
M
M
L
S
A
L
F
-
G
V
K
P
A
-
W
F
S
D
P
T
T
A
R
T
M
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
--
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
M
I
A
S
F
A
F
N
F
N
N
-
F
V
L
I
Q
L
L
T
N
G
G
P
---
D
R
--------
L
G
T
T
T
P
A
G
Y
T
D
L
LVNYT
Y
R
I
---
A
F
E
G
G
G
G
Q
D
F
G
L
A
A
A
I
A
T
L
I
F
L
L
V
G
A
L
A
I
---------
12
PsiBlast_PDB
67.35
28%
-90
- C2 -
3RLF
2
MALF_ECOLI
F:
[259-503]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
W
K
N
F
T
R
V
F
T
D
E
G
----
I
Q
K
PFLA
I
F
V
W
T
V
V
F
S
L
I
T
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
W
E
--
A
-
L
R
G
K
A
V
Y
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
F
K
G
L
F
N
Q
S
F
G
E
I
N
M
M
L
S
A
L
F
-
G
V
K
P
A
-
W
F
S
D
P
T
T
A
R
T
M
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
--
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
M
I
A
S
F
A
F
N
F
N
N
-
F
V
L
I
Q
L
L
T
N
G
G
P
---
D
R
--------
L
G
T
T
T
P
A
G
Y
T
D
L
LVNYT
Y
R
I
---
A
F
E
G
G
G
G
Q
D
F
G
L
A
A
A
I
A
T
L
I
F
L
L
V
G
A
L
A
I
---------
32
HHSearch
67.03
20%
-146
* C2 *
2ONK
-
WTPB_ARCFU
C:
[26-275]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
F
S
A
L
L
A
L
L
S
S
I
I
L
L
F
V
L
L
P
V
A
--
A
T
V
T
L
Q
L
F
------------
N
F
D
E
F
L
K
A
A
S
D
P
A
----
V
W
K
----
V
V
L
T
T
Y
Y
A
A
L
I
S
T
L
I
A
V
I
F
G
T
P
L
A
Y
I
L
A
-
R
K-
S
-
F
P
G
K
S
V
V
E
G
I
V
D
L
P
V
V
I
P
H
T
V
A
G
I
A
L
L
V
V
F
G
S
-
S
G
L
I
G
S
F
S
-
P
-------
L
K
F
----
V
D
A
L
P
G
I
V
V
A
M
L
F
V
S
V
P
I
Y
I
N
Q
--
A
K
E
G
F
A
S
V
D
V
R
L
E
H
V
A
R
T
L
G
S
S
P
L
R
V
F
F
T
V
S
L
P
L
S
V
R
H
I
V
A
G
A
I
M
S
W
A
R
G
I
S
E
-
F
G
A
V
V
V
I
--
A
Y
Y
--------------
P
M
I
A
P
T
L
I
Y
E
R
-----
Y
L
S
----
E
G
L
S
A
A
M
P
V
A
A
I
L
I
L
L
S
L
A
V
F
V
A
-
L
R
I
I
V
G
-------
6
PsiBlast_PDB
66.84
28%
-92
- C2 -
3PUY
2
MALF_ECOLI
F:
[259-503]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
W
K
N
F
T
R
V
F
T
D
E
G
----
I
Q
K
PFLA
I
F
V
W
T
V
V
F
S
L
I
T
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
W
E
--
A
-
L
R
G
K
A
V
Y
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
F
K
G
L
F
N
Q
S
F
G
E
I
N
M
M
L
S
A
L
F
-
G
V
K
P
A
-
W
F
S
D
P
T
T
A
R
T
M
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
--
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
M
I
A
S
F
A
F
N
F
N
N
-
F
V
L
I
Q
L
L
T
N
G
G
P
---
D
R
--------
L
G
T
T
T
P
A
G
Y
T
D
L
LVNYT
Y
R
I
---
A
F
E
G
G
G
G
Q
D
F
G
L
A
A
A
I
A
T
L
I
F
L
L
V
G
A
L
A
I
---------
10
PsiBlast_PDB
66.29
28%
-92
- C2 -
3PUW
3
MALF_ECOLI
F:
[259-503]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
W
K
N
F
T
R
V
F
T
D
E
G
----
I
Q
K
PFLA
I
F
V
W
T
V
V
F
S
L
I
T
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
W
E
--
A
-
L
R
G
K
A
V
Y
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
F
K
G
L
F
N
Q
S
F
G
E
I
N
M
M
L
S
A
L
F
-
G
V
K
P
A
-
W
F
S
D
P
T
T
A
R
T
M
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
--
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
M
I
A
S
F
A
F
N
F
N
N
-
F
V
L
I
Q
L
L
T
N
G
G
P
---
D
R
--------
L
G
T
T
T
P
A
G
Y
T
D
L
LVNYT
Y
R
I
---
A
F
E
G
G
G
G
Q
D
F
G
L
A
A
A
I
A
T
L
I
F
L
L
V
G
A
L
A
I
---------
7
PsiBlast_PDB
66.09
28%
-83
- C2 -
3PUZ
2
MALF_ECOLI
F:
[259-503]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
W
K
N
F
T
R
V
F
T
D
E
G
----
I
Q
K
PFLA
I
F
V
W
T
V
V
F
S
L
I
T
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
W
E
--
A
-
L
R
G
K
A
V
Y
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
F
K
G
L
F
N
Q
S
F
G
E
I
N
M
M
L
S
A
L
F
-
G
V
K
P
A
-
W
F
S
D
P
T
T
A
R
T
M
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
--
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
M
I
A
S
F
A
F
N
F
N
N
-
F
V
L
I
Q
L
L
T
N
G
G
P
---
D
R
--------
L
G
T
T
T
P
A
G
Y
T
D
L
LVNYT
Y
R
I
---
A
F
E
G
G
G
G
Q
D
F
G
L
A
A
A
I
A
T
L
I
F
L
L
V
G
A
L
A
I
---------
9
PsiBlast_PDB
65.68
28%
-95
- C2 -
3PUV
3
MALF_ECOLI
F:
[259-503]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
W
K
N
F
T
R
V
F
T
D
E
G
----
I
Q
K
PFLA
I
F
V
W
T
V
V
F
S
L
I
T
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
W
E
--
A
-
L
R
G
K
A
V
Y
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
F
K
G
L
F
N
Q
S
F
G
E
I
N
M
M
L
S
A
L
F
-
G
V
K
P
A
-
W
F
S
D
P
T
T
A
R
T
M
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
--
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
M
I
A
S
F
A
F
N
F
N
N
-
F
V
L
I
Q
L
L
T
N
G
G
P
---
D
R
--------
L
G
T
T
T
P
A
G
Y
T
D
L
LVNYT
Y
R
I
---
A
F
E
G
G
G
G
Q
D
F
G
L
A
A
A
I
A
T
L
I
F
L
L
V
G
A
L
A
I
---------
22
Fugue
63.66
18%
-139
- C2 -
2ONK
-
WTPB_ARCFU
C:
[24-275]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
R
L
L
F
S
A
L
L
A
L
L
S
S
I
I
L
L
F
V
L
L
P
V
A
--
A
T
V
T
L
Q
L
F
N
------------
F
D
E
F
L
K
A
A
S
D
P
A
----
V
W
K
----
V
V
L
T
T
Y
Y
A
A
L
I
S
T
L
I
A
V
I
F
G
T
P
L
A
Y
I
L
A
-
R
K-
S
-
F
P
G
K
S
V
V
E
G
I
V
D
L
P
V
V
I
P
H
T
V
A
G
I
A
L
L
V
V
F
G
S
S
G
---------------
L
I
G
S
F
S
P
L
K
F
V
D
A
L
P
G
I
V
V
A
M
L
F
V
S
V
P
I
Y
I
NQ
A
K
E
G
F
A
S
V
D
V
R
L
E
H
V
A
R
T
L
G
S
S
P
L
R
V
F
F
T
V
S
L
P
L
S
V
R
H
I
V
A
G
A
I
M
S
W
A
R
G
I
S
E
-
F
G
A
V
V
V
I
---------------------
A
Y
Y
P
M
I
A
P
T
-----
L
I
Y
---
E
R
Y
L
S
E
G
L
S
A
A
M
P
V
A
A
I
L
I
L
L
S
L
A
-
V
F
V
A
L
R
I
I
V
G
---