@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu31100: (2016-07-21 )
MTLQKDKVIKWVRFTPPQVLAIGFFLTIIIGAVLLMLPISTTKPLSWIDALFTAASATTVTGLAVVDTGTQFTVFGQTVIMGLIQIGGLGFMTFAVLIVMILGKKIGLKERMLVQEALNQPTIGGVIGLVKVLFLFSISIELIAALILSIRLVPQYGWSSGLFASLFHAISAFNNAGFSLWPDNLMSYVGDPTVNLVITFLFITGGIGFTVLFDVMKNRRFKTFSLHTKLMLTGTLMLNAIAMLTVFILEYSNPGTLGHLHIVDKLWASYFQAVTPRTAGFNSLDFGSMREGTIVFTLLLMFIGAGSASTASGIKLTTFIVILTSVIAYLRGKKETVIFRRSIKYPIIIKALAVSVTSLFIVFLGIFALTITEQAPFLQIVFETFSAFGTVGLTMGLTPELTTAGKCIIIVIMFIGRIGPLTFVFSFAKTEQSNIRYPDGEVFTG
Atome Classification :
(20 SA)
----------------------------------------.........10......-----------..20........30........40........50........60-------.........70...-.....80........90........100.......110...-------....--120--.-.......130.......140.......150........160.......170....-....180.......------190--.......200.......210--------------......--------.-..--220..-------------.......230.......---240.......--.250........--260.......270....-...-280.-.------...--.--.--290......--------.300.......310.......320..-.....330....------...340.......350..--------.....360...--------....370.------------...----.--------------..380.----------......390......----.--------400--.........410.....--------..420.----......430--.......440...------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------MTL
Q
K
D
K
V
I
K
W
V
RFTP
P
-----------
Q
V
L
A
I
G
F
F
L
T
I
I
I
G
A
V
L
L
MLPISTTK
P
L
S
W
I
D
A
L
F
TAASA
T
T
V
--------
T
G
L
A
V
VDTGT
Q
F
T
V
-
F
G
Q
T
V
I
M
G
L
I
Q
IG
G
L
G
F
M
T
F
A
V
L
I
V
M
I
L
GKKI
G
L
K
E
R
M
L
V
Q
-------
E
A
LN--QP---T-I
G
G
V
I
G
L
V
K
V
L
F
L
F
S
I
S
I
E
L
I
A
A
L
I
L
S
I
R
-
L
VPQYGWSS
G
L
F
A
S
L
F
H
A
I
-
S
A
F
NN-AGFSL
W
P
D
N
L
M
S
Y
V------GDP--T
V
N
L
V
I
T
F
L
F
ITGG
I
G
F
T
----------------
V
L
F
D
V
M
--------K-NR--
R
--
F
K
-------------
T
F
S
L
H
T
K
L
M
L
T
G
T
L
M
L
N
---
A
I
-
A
M
L
T
V
F
I
--LE-YSNPGTL
G
H
--
L
H
I
V
D
K
L
W
A
S
Y
F
Q
A
VTP-RTA-GFNS-L------DFG--S--M--RE
G
T
I
V
F
T
L
--------
L
L
M
F
IGAGSASTASG
I
K
L
T
T
F
I
V
I
L
T
-
S
V
I
A
Y
LRGKK
E
T
------
V
I
F
RRSIKY
P
I
I
I
K
A
L
A
V
--------
S
V
T
S
L
F
I
V
F
L
G
--------
I
F
A
L
TITE------------QA
P
----
F
--------------
L
Q
I
V
F
E
----------
T
F
S
A
FGTVGLTMGLT----P--------E----LTTAG
K
C
I
I
I
V
I
M
F
I
GR--------IG
P
L
T
F
----
V
F
S
FAKTEQ--SNIRYPDGEVFTG------------------------------------------
30
Fugue
85.85
100%
-147
- C3 -
4J7C
1
KTRB_BACSU
I:
[35-465]
------------------------------------------------------
T
P
P
-----------
Q
V
L
A
I
G
F
F
L
T
I
I
I
G
A
V
L
L
M
L
P
I
S
T
T
K
P
L
S
W
I
D
A
L
F
T
A
A
S
A
T
T
V
--------
T
G
L
A
V
V
D
T
G
T
Q
F
T
V
-
F
G
Q
T
V
I
M
G
L
I
Q
I
G
G
L
G
F
M
T
F
A
V
L
I
V
M
I
L
--
K
I
G
L
K
E
R
M
L
V
Q
-------
E
A
L
N
--
Q
P
---
T
-
I
G
G
V
I
G
L
V
K
V
L
F
L
F
S
I
S
I
E
L
I
A
A
L
I
L
S
I
R
-
L
V
P
Q
Y
G
W
S
S
G
L
F
A
S
L
F
H
A
I
-
S
A
F
N
N
-
A
G
F
S
L
W
P
D
N
L
M
S
Y
V
------
G
D
P
--
T
V
N
L
V
I
T
F
L
F
I
T
G
G
I
G
F
T
----------------
V
L
F
D
V
M
--------
K
-
N
R
--
R
--
F
K
-------------
T
F
S
L
H
T
K
L
M
L
T
G
T
L
M
L
N
---
A
I
-
A
M
L
T
V
F
I
--
L
E
-
Y
S
N
P
G
T
L
G
H
--
L
H
I
V
D
K
L
W
A
S
Y
F
Q
A
V
T
P
-
R
T
A
-
G
F
N
S
-
L
------
D
F
G
--
S
--
M
--
R
E
G
T
I
V
F
T
L
--------
L
L
M
F
I
G
A
G
S
A
S
T
A
S
G
I
K
L
T
T
F
I
V
I
L
T
-
S
V
I
A
Y
L
R
G
K
K
E
T
------
V
I
F
R
R
S
I
K
Y
P
I
I
I
K
A
L
A
V
--------
S
V
T
S
L
F
I
V
F
L
G
--------
I
F
A
L
T
I
T
E
------------
Q
A
P
----
F
--------------
L
Q
I
V
F
E
----------
T
F
S
A
F
G
T
V
G
L
T
M
G
L
T
----
P
--------
E
----
L
T
T
A
G
K
C
I
I
I
V
I
M
F
I
G
R
--------
I
G
P
L
T
F
----
V
F
S
F
A
K
T
E
Q
--
S
N
I
R
Y
P
D
G
E
V
F
T
G
------------------------------------------
22
PsiBlast_PDB
85.85
100%
-147
- C3 -
4J7C
1
KTRB_BACSU
I:
[35-465]
------------------------------------------------------
T
P
P
-----------
Q
V
L
A
I
G
F
F
L
T
I
I
I
G
A
V
L
L
M
L
P
I
S
T
T
K
P
L
S
W
I
D
A
L
F
T
A
A
S
A
T
T
V
--------
T
G
L
A
V
V
D
T
G
T
Q
F
T
V
-
F
G
Q
T
V
I
M
G
L
I
Q
I
G
G
L
G
F
M
T
F
A
V
L
I
V
M
I
L
--
K
I
G
L
K
E
R
M
L
V
Q
-------
E
A
L
N
--
Q
P
---
T
-
I
G
G
V
I
G
L
V
K
V
L
F
L
F
S
I
S
I
E
L
I
A
A
L
I
L
S
I
R
-
L
V
P
Q
Y
G
W
S
S
G
L
F
A
S
L
F
H
A
I
-
S
A
F
N
N
-
A
G
F
S
L
W
P
D
N
L
M
S
Y
V
------
G
D
P
--
T
V
N
L
V
I
T
F
L
F
I
T
G
G
I
G
F
T
----------------
V
L
F
D
V
M
--------
K
-
N
R
--
R
--
F
K
-------------
T
F
S
L
H
T
K
L
M
L
T
G
T
L
M
L
N
---
A
I
-
A
M
L
T
V
F
I
--
L
E
-
Y
S
N
P
G
T
L
G
H
--
L
H
I
V
D
K
L
W
A
S
Y
F
Q
A
V
T
P
-
R
T
A
-
G
F
N
S
-
L
------
D
F
G
--
S
--
M
--
R
E
G
T
I
V
F
T
L
--------
L
L
M
F
I
G
A
G
S
A
S
T
A
S
G
I
K
L
T
T
F
I
V
I
L
T
-
S
V
I
A
Y
L
R
G
K
K
E
T
------
V
I
F
R
R
S
I
K
Y
P
I
I
I
K
A
L
A
V
--------
S
V
T
S
L
F
I
V
F
L
G
--------
I
F
A
L
T
I
T
E
------------
Q
A
P
----
F
--------------
L
Q
I
V
F
E
----------
T
F
S
A
F
G
T
V
G
L
T
M
G
L
T
----
P
--------
E
----
L
T
T
A
G
K
C
I
I
I
V
I
M
F
I
G
R
--------
I
G
P
L
T
F
----
V
F
S
F
A
K
T
E
Q
--
S
N
I
R
Y
P
D
G
E
V
F
T
G
------------------------------------------
26
PsiBlast_CBE
85.84
100%
-148
- C3 -
4J7C
1
KTRB_BACSU
J:
[35-465]
------------------------------------------------------
T
P
P
-----------
Q
V
L
A
I
G
F
F
L
T
I
I
I
G
A
V
L
L
M
L
P
I
S
T
T
K
P
L
S
W
I
D
A
L
F
T
A
A
S
A
T
T
V
--------
T
G
L
A
V
V
D
T
G
T
Q
F
T
V
-
F
G
Q
T
V
I
M
G
L
I
Q
I
G
G
L
G
F
M
T
F
A
V
L
I
V
M
I
L
--
K
I
G
L
K
E
R
M
L
V
Q
-------
E
A
L
N
--
Q
P
---
T
-
I
G
G
V
I
G
L
V
K
V
L
F
L
F
S
I
S
I
E
L
I
A
A
L
I
L
S
I
R
-
L
V
P
Q
Y
G
W
S
S
G
L
F
A
S
L
F
H
A
I
-
S
A
F
N
N
-
A
G
F
S
L
W
P
D
N
L
M
S
Y
V
------
G
D
P
--
T
V
N
L
V
I
T
F
L
F
I
T
G
G
I
G
F
T
----------------
V
L
F
D
V
M
--------
K
-
N
R
--
R
--
F
K
-------------
T
F
S
L
H
T
K
L
M
L
T
G
T
L
M
L
N
---
A
I
-
A
M
L
T
V
F
I
--
L
E
-
Y
S
N
P
G
T
L
G
H
--
L
H
I
V
D
K
L
W
A
S
Y
F
Q
A
V
T
P
-
R
T
A
-
G
F
N
S
-
L
------
D
F
G
--
S
--
M
--
R
E
G
T
I
V
F
T
L
--------
L
L
M
F
I
G
A
G
S
A
S
T
A
S
G
I
K
L
T
T
F
I
V
I
L
T
-
S
V
I
A
Y
L
R
G
K
K
E
T
------
V
I
F
R
R
S
I
K
Y
P
I
I
I
K
A
L
A
V
--------
S
V
T
S
L
F
I
V
F
L
G
--------
I
F
A
L
T
I
T
E
------------
Q
A
P
----
F
--------------
L
Q
I
V
F
E
----------
T
F
S
A
F
G
T
V
G
L
T
M
G
L
T
----
P
--------
E
----
L
T
T
A
G
K
C
I
I
I
V
I
M
F
I
G
R
--------
I
G
P
L
T
F
----
V
F
S
F
A
K
T
E
Q
--
S
N
I
R
Y
P
D
G
E
V
F
T
G
------------------------------------------
25
PsiBlast_CBE
85.82
100%
-149
- C3 -
4J7C
1
KTRB_BACSU
K:
[35-465]
------------------------------------------------------
T
P
P
-----------
Q
V
L
A
I
G
F
F
L
T
I
I
I
G
A
V
L
L
M
L
P
I
S
T
T
K
P
L
S
W
I
D
A
L
F
T
A
A
S
A
T
T
V
--------
T
G
L
A
V
V
D
T
G
T
Q
F
T
V
-
F
G
Q
T
V
I
M
G
L
I
Q
I
G
G
L
G
F
M
T
F
A
V
L
I
V
M
I
L
--
K
I
G
L
K
E
R
M
L
V
Q
-------
E
A
L
N
--
Q
P
---
T
-
I
G
G
V
I
G
L
V
K
V
L
F
L
F
S
I
S
I
E
L
I
A
A
L
I
L
S
I
R
-
L
V
P
Q
Y
G
W
S
S
G
L
F
A
S
L
F
H
A
I
-
S
A
F
N
N
-
A
G
F
S
L
W
P
D
N
L
M
S
Y
V
------
G
D
P
--
T
V
N
L
V
I
T
F
L
F
I
T
G
G
I
G
F
T
----------------
V
L
F
D
V
M
--------
K
-
N
R
--
R
--
F
K
-------------
T
F
S
L
H
T
K
L
M
L
T
G
T
L
M
L
N
---
A
I
-
A
M
L
T
V
F
I
--
L
E
-
Y
S
N
P
G
T
L
G
H
--
L
H
I
V
D
K
L
W
A
S
Y
F
Q
A
V
T
P
-
R
T
A
-
G
F
N
S
-
L
------
D
F
G
--
S
--
M
--
R
E
G
T
I
V
F
T
L
--------
L
L
M
F
I
G
A
G
S
A
S
T
A
S
G
I
K
L
T
T
F
I
V
I
L
T
-
S
V
I
A
Y
L
R
G
K
K
E
T
------
V
I
F
R
R
S
I
K
Y
P
I
I
I
K
A
L
A
V
--------
S
V
T
S
L
F
I
V
F
L
G
--------
I
F
A
L
T
I
T
E
------------
Q
A
P
----
F
--------------
L
Q
I
V
F
E
----------
T
F
S
A
F
G
T
V
G
L
T
M
G
L
T
----
P
--------
E
----
L
T
T
A
G
K
C
I
I
I
V
I
M
F
I
G
R
--------
I
G
P
L
T
F
----
V
F
S
F
A
K
T
E
Q
--
S
N
I
R
Y
P
D
G
E
V
F
T
G
------------------------------------------
24
PsiBlast_CBE
85.51
100%
-147
- C3 -
4J7C
1
KTRB_BACSU
L:
[35-465]
------------------------------------------------------
T
P
P
-----------
Q
V
L
A
I
G
F
F
L
T
I
I
I
G
A
V
L
L
M
L
P
I
S
T
T
K
P
L
S
W
I
D
A
L
F
T
A
A
S
A
T
T
V
--------
T
G
L
A
V
V
D
T
G
T
Q
F
T
V
-
F
G
Q
T
V
I
M
G
L
I
Q
I
G
G
L
G
F
M
T
F
A
V
L
I
V
M
I
L
--
K
I
G
L
K
E
R
M
L
V
Q
-------
E
A
L
N
--
Q
P
---
T
-
I
G
G
V
I
G
L
V
K
V
L
F
L
F
S
I
S
I
E
L
I
A
A
L
I
L
S
I
R
-
L
V
P
Q
Y
G
W
S
S
G
L
F
A
S
L
F
H
A
I
-
S
A
F
N
N
-
A
G
F
S
L
W
P
D
N
L
M
S
Y
V
------
G
D
P
--
T
V
N
L
V
I
T
F
L
F
I
T
G
G
I
G
F
T
----------------
V
L
F
D
V
M
--------
K
-
N
R
--
R
--
F
K
-------------
T
F
S
L
H
T
K
L
M
L
T
G
T
L
M
L
N
---
A
I
-
A
M
L
T
V
F
I
--
L
E
-
Y
S
N
P
G
T
L
G
H
--
L
H
I
V
D
K
L
W
A
S
Y
F
Q
A
V
T
P
-
R
T
A
-
G
F
N
S
-
L
------
D
F
G
--
S
--
M
--
R
E
G
T
I
V
F
T
L
--------
L
L
M
F
I
G
A
G
S
A
S
T
A
S
G
I
K
L
T
T
F
I
V
I
L
T
-
S
V
I
A
Y
L
R
G
K
K
E
T
------
V
I
F
R
R
S
I
K
Y
P
I
I
I
K
A
L
A
V
--------
S
V
T
S
L
F
I
V
F
L
G
--------
I
F
A
L
T
I
T
E
------------
Q
A
P
----
F
--------------
L
Q
I
V
F
E
----------
T
F
S
A
F
G
T
V
G
L
T
M
G
L
T
----
P
--------
E
----
L
T
T
A
G
K
C
I
I
I
V
I
M
F
I
G
R
--------
I
G
P
L
T
F
----
V
F
S
F
A
K
T
E
Q
--
S
N
I
R
Y
P
D
G
E
V
F
T
G
------------------------------------------
27
PsiBlast_CBE
82.76
98%
-150
- C3 -
5BUT
1
KTRB_BACSU
L:
[15-445]
------------------------------------------------------
T
P
P
-----------
Q
V
L
A
I
G
F
F
L
T
I
I
I
G
A
V
L
L
M
L
P
I
S
T
T
K
P
L
S
W
I
D
A
L
F
T
A
A
S
A
T
T
V
--------
T
G
L
A
V
V
D
T
G
T
Q
F
T
V
-
F
G
Q
T
V
I
M
G
L
I
Q
I
G
G
L
G
F
M
T
F
A
V
L
I
V
M
I
L
A
A
A
I
G
L
K
E
R
M
L
V
Q
-------
E
A
L
N
--
Q
P
---
T
-
I
G
G
V
I
G
L
V
K
V
L
F
L
F
S
I
S
I
E
L
I
A
A
L
I
L
S
I
R
-
L
V
P
Q
Y
G
W
S
S
G
L
F
A
S
L
F
H
A
I
-
S
A
F
N
N
-
A
G
F
S
L
W
P
D
N
L
M
S
Y
V
------
G
D
P
--
T
V
N
L
V
I
T
F
L
F
I
T
G
G
I
G
F
T
----------------
V
L
F
D
V
M
--------
K
-
Q
R
--
R
--
F
K
-------------
T
F
S
L
H
T
A
L
M
L
T
G
T
L
M
L
N
---
A
I
-
A
M
L
T
V
F
I
--
L
E
-
Y
S
N
P
G
T
L
G
H
--
L
A
A
V
D
K
L
W
A
S
Y
F
Q
A
V
T
P
-
R
T
A
-
G
F
N
S
-
L
------
D
F
G
--
S
--
M
--
R
E
G
T
I
V
F
T
L
--------
L
L
M
F
I
G
A
G
S
A
S
T
A
S
G
I
K
L
T
T
F
I
V
I
L
T
-
S
V
I
A
Y
L
R
G
K
K
E
T
------
V
I
F
R
R
S
I
K
Y
P
I
I
I
K
A
L
A
V
--------
S
V
T
S
L
F
I
V
F
L
G
--------
I
F
A
L
T
I
T
E
------------
Q
A
P
----
F
--------------
L
Q
I
V
F
E
----------
T
F
S
A
F
G
T
V
G
L
T
M
G
L
T
----
P
--------
E
----
L
T
T
A
G
K
C
I
I
I
V
I
M
F
I
G
R
--------
I
G
P
L
T
F
----
V
F
S
F
A
A
T
E
Q
--
S
N
I
R
Y
P
D
G
E
V
F
T
G
------------------------------------------
23
PsiBlast_PDB
82.60
98%
-150
- C3 -
5BUT
1
KTRB_BACSU
I:
[15-445]
------------------------------------------------------
T
P
P
-----------
Q
V
L
A
I
G
F
F
L
T
I
I
I
G
A
V
L
L
M
L
P
I
S
T
T
K
P
L
S
W
I
D
A
L
F
T
A
A
S
A
T
T
V
--------
T
G
L
A
V
V
D
T
G
T
Q
F
T
V
-
F
G
Q
T
V
I
M
G
L
I
Q
I
G
G
L
G
F
M
T
F
A
V
L
I
V
M
I
L
A
A
A
I
G
L
K
E
R
M
L
V
Q
-------
E
A
L
N
--
Q
P
---
T
-
I
G
G
V
I
G
L
V
K
V
L
F
L
F
S
I
S
I
E
L
I
A
A
L
I
L
S
I
R
-
L
V
P
Q
Y
G
W
S
S
G
L
F
A
S
L
F
H
A
I
-
S
A
F
N
N
-
A
G
F
S
L
W
P
D
N
L
M
S
Y
V
------
G
D
P
--
T
V
N
L
V
I
T
F
L
F
I
T
G
G
I
G
F
T
----------------
V
L
F
D
V
M
--------
K
-
Q
R
--
R
--
F
K
-------------
T
F
S
L
H
T
A
L
M
L
T
G
T
L
M
L
N
---
A
I
-
A
M
L
T
V
F
I
--
L
E
-
Y
S
N
P
G
T
L
G
H
--
L
A
A
V
D
K
L
W
A
S
Y
F
Q
A
V
T
P
-
R
T
A
-
G
F
N
S
-
L
------
D
F
G
--
S
--
M
--
R
E
G
T
I
V
F
T
L
--------
L
L
M
F
I
G
A
G
S
A
S
T
A
S
G
I
K
L
T
T
F
I
V
I
L
T
-
S
V
I
A
Y
L
R
G
K
K
E
T
------
V
I
F
R
R
S
I
K
Y
P
I
I
I
K
A
L
A
V
--------
S
V
T
S
L
F
I
V
F
L
G
--------
I
F
A
L
T
I
T
E
------------
Q
A
P
----
F
--------------
L
Q
I
V
F
E
----------
T
F
S
A
F
G
T
V
G
L
T
M
G
L
T
----
P
--------
E
----
L
T
T
A
G
K
C
I
I
I
V
I
M
F
I
G
R
--------
I
G
P
L
T
F
----
V
F
S
F
A
A
T
E
Q
--
S
N
I
R
Y
P
D
G
E
V
F
T
G
------------------------------------------
1
HHSearch
82.46
95%
-136
- C3 -
4J7C
1
KTRB_BACSU
I:
[35-465]
------------------------------------------------------
T
P
P
-----------
Q
V
L
A
I
G
F
F
L
T
I
I
I
G
A
V
L
L
M
L
P
I
S
T
T
K
P
L
S
W
I
D
A
L
F
T
A
A
S
A
T
T
V
--------
T
G
L
A
V
V
D
T
G
T
Q
F
T
V
F
G
Q
T
V
I
M
G
L
I
-
Q
I
G
G
L
G
F
M
T
F
A
V
L
I
V
M
I
L
--
K
I
G
L
K
E
-
R
M
L
V
-------
Q
E
A
L
--
N
Q
---
P
T
I
G
G
V
I
G
L
V
K
V
L
F
L
F
S
I
S
I
E
L
I
A
A
L
I
L
S
I
R
-
L
V
P
Q
Y
G
W
S
S
G
L
F
A
S
L
F
H
A
I
-
S
A
F
N
N
-
A
G
F
S
L
W
P
D
N
L
M
S
Y
V
------
G
D
P
--
T
V
N
L
V
I
T
F
L
F
I
T
G
G
I
G
F
T
----------------
V
L
F
D
V
M
--------
K
-
N
R
--
R
--
F
K
-------------
T
F
S
L
H
T
K
L
M
L
T
G
T
L
M
L
N
---
A
I
-
A
M
L
T
V
F
I
--
L
E
-
Y
S
N
P
G
T
L
G
H
--
L
H
I
V
D
K
L
W
A
S
Y
F
Q
A
V
T
P
-
R
T
A
-
G
F
N
S
-
L
------
D
F
G
--
S
--
M
--
R
E
G
T
I
V
F
T
L
--------
L
L
M
F
I
G
A
G
S
A
S
T
A
S
G
I
K
L
T
T
F
I
V
I
L
T
-
S
V
I
A
Y
L
R
G
K
K
E
T
------
V
I
F
R
R
S
I
K
Y
P
I
I
I
K
A
L
A
V
--------
S
V
T
S
L
F
I
V
F
L
G
--------
I
F
A
L
T
I
T
E
------------
Q
A
P
----
F
--------------
L
Q
I
V
F
E
----------
T
F
S
A
F
G
T
V
G
L
T
M
G
L
T
----
P
--------
E
----
L
T
T
A
G
K
C
I
I
I
V
I
M
F
I
G
R
--------
I
G
P
L
T
F
----
V
F
S
F
A
K
T
E
Q
--
S
N
I
R
Y
P
D
G
E
V
F
T
G
------------------------------------------
28
PsiBlast_CBE
82.10
98%
-150
- C3 -
5BUT
1
KTRB_BACSU
K:
[15-445]
------------------------------------------------------
T
P
P
-----------
Q
V
L
A
I
G
F
F
L
T
I
I
I
G
A
V
L
L
M
L
P
I
S
T
T
K
P
L
S
W
I
D
A
L
F
T
A
A
S
A
T
T
V
--------
T
G
L
A
V
V
D
T
G
T
Q
F
T
V
-
F
G
Q
T
V
I
M
G
L
I
Q
I
G
G
L
G
F
M
T
F
A
V
L
I
V
M
I
L
A
A
A
I
G
L
K
E
R
M
L
V
Q
-------
E
A
L
N
--
Q
P
---
T
-
I
G
G
V
I
G
L
V
K
V
L
F
L
F
S
I
S
I
E
L
I
A
A
L
I
L
S
I
R
-
L
V
P
Q
Y
G
W
S
S
G
L
F
A
S
L
F
H
A
I
-
S
A
F
N
N
-
A
G
F
S
L
W
P
D
N
L
M
S
Y
V
------
G
D
P
--
T
V
N
L
V
I
T
F
L
F
I
T
G
G
I
G
F
T
----------------
V
L
F
D
V
M
--------
K
-
Q
R
--
R
--
F
K
-------------
T
F
S
L
H
T
A
L
M
L
T
G
T
L
M
L
N
---
A
I
-
A
M
L
T
V
F
I
--
L
E
-
Y
S
N
P
G
T
L
G
H
--
L
A
A
V
D
K
L
W
A
S
Y
F
Q
A
V
T
P
-
R
T
A
-
G
F
N
S
-
L
------
D
F
G
--
S
--
M
--
R
E
G
T
I
V
F
T
L
--------
L
L
M
F
I
G
A
G
S
A
S
T
A
S
G
I
K
L
T
T
F
I
V
I
L
T
-
S
V
I
A
Y
L
R
G
K
K
E
T
------
V
I
F
R
R
S
I
K
Y
P
I
I
I
K
A
L
A
V
--------
S
V
T
S
L
F
I
V
F
L
G
--------
I
F
A
L
T
I
T
E
------------
Q
A
P
----
F
--------------
L
Q
I
V
F
E
----------
T
F
S
A
F
G
T
V
G
L
T
M
G
L
T
----
P
--------
E
----
L
T
T
A
G
K
C
I
I
I
V
I
M
F
I
G
R
--------
I
G
P
L
T
F
----
V
F
S
F
A
A
T
E
Q
--
S
N
I
R
Y
P
D
G
E
V
F
T
G
------------------------------------------
29
PsiBlast_CBE
81.75
98%
-148
- C3 -
5BUT
1
KTRB_BACSU
J:
[15-445]
------------------------------------------------------
T
P
P
-----------
Q
V
L
A
I
G
F
F
L
T
I
I
I
G
A
V
L
L
M
L
P
I
S
T
T
K
P
L
S
W
I
D
A
L
F
T
A
A
S
A
T
T
V
--------
T
G
L
A
V
V
D
T
G
T
Q
F
T
V
-
F
G
Q
T
V
I
M
G
L
I
Q
I
G
G
L
G
F
M
T
F
A
V
L
I
V
M
I
L
A
A
A
I
G
L
K
E
R
M
L
V
Q
-------
E
A
L
N
--
Q
P
---
T
-
I
G
G
V
I
G
L
V
K
V
L
F
L
F
S
I
S
I
E
L
I
A
A
L
I
L
S
I
R
-
L
V
P
Q
Y
G
W
S
S
G
L
F
A
S
L
F
H
A
I
-
S
A
F
N
N
-
A
G
F
S
L
W
P
D
N
L
M
S
Y
V
------
G
D
P
--
T
V
N
L
V
I
T
F
L
F
I
T
G
G
I
G
F
T
----------------
V
L
F
D
V
M
--------
K
-
Q
R
--
R
--
F
K
-------------
T
F
S
L
H
T
A
L
M
L
T
G
T
L
M
L
N
---
A
I
-
A
M
L
T
V
F
I
--
L
E
-
Y
S
N
P
G
T
L
G
H
--
L
A
A
V
D
K
L
W
A
S
Y
F
Q
A
V
T
P
-
R
T
A
-
G
F
N
S
-
L
------
D
F
G
--
S
--
M
--
R
E
G
T
I
V
F
T
L
--------
L
L
M
F
I
G
A
G
S
A
S
T
A
S
G
I
K
L
T
T
F
I
V
I
L
T
-
S
V
I
A
Y
L
R
G
K
K
E
T
------
V
I
F
R
R
S
I
K
Y
P
I
I
I
K
A
L
A
V
--------
S
V
T
S
L
F
I
V
F
L
G
--------
I
F
A
L
T
I
T
E
------------
Q
A
P
----
F
--------------
L
Q
I
V
F
E
----------
T
F
S
A
F
G
T
V
G
L
T
M
G
L
T
----
P
--------
E
----
L
T
T
A
G
K
C
I
I
I
V
I
M
F
I
G
R
--------
I
G
P
L
T
F
----
V
F
S
F
A
A
T
E
Q
--
S
N
I
R
Y
P
D
G
E
V
F
T
G
------------------------------------------
31
Fugue
50.18
19%
-123
- C3 -
3PJZ
1
TRKH_VIBPA
A:
[1-484]
MQ
F
R
S
I
I
R
I
V
G
L
L
L
A
L
F
S
V
T
M
L
A
P
A
L
V
A
L
L
Y
RDGAG
V
P
F
V
T
T
F
F
V
L
L
F
C
G
A
M
C
W
F
P
N
RRHKHELK
S
R
D
G
F
L
I
V
V
L
F
W
T
V
L
G
S
A
G
S
L
P
F
L
I
A
D
N
P
N
I
S
V
T
D
A
F
F
E
S
F
S
A
L
T
T
--------
T
G
A
T
V
I
V
G
L
D
E
L
P
K
-
A
I
L
F
Y
R
Q
F
L
Q
W
F
G
G
M
G
I
I
V
L
A
V
A
I
L
P
V
L
G
I
G
G
M
T
P
R
I
A
E
T
A
-------
K
A
L
W
--
Y
I
---
Y
-
L
S
L
T
I
A
C
A
V
A
F
W
L
A
G
M
T
-----------------------
P
F
D
A
I
S
H
S
F
-
S
T
I
A
I
-
G
G
F
S
T
-
H
D
A
S
M
G
Y
F
------
D
S
Y
--
A
I
N
L
I
T
V
V
F
L
L
I
S
A
C
N
F
T
----------------
L
H
F
A
A
F
--------
A
-
S
G
GV
H
--
P
K
-------------
Y
Y
W
K
D
P
E
F
R
A
F
I
F
I
Q
V
L
---
L
F
-
L
V
C
F
L
L
L
--
L
K
-
H
H
S
Y
T
S
-------
P
Y
D
A
F
D
Q
A
L
F
Q
T
V
S
I
-
S
T
T
A
G
F
T
T
-
T
------
G
F
A
--
D
--
W
--
P
L
F
L
P
V
L
L
L
--------
F
S
S
F
I
G
G
C
A
G
S
T
G
G
G
M
K
V
I
R
I
L
L
L
T
L
Q
G
A
R
E
L
K
R
L
V
H
P
R
------
A
V
Y
T
I
K
V
G
G
S
A
L
P
Q
R
V
V
D
--------
A
V
W
G
F
F
S
A
Y
A
L
--------
V
F
V
V
C
M
L
G
------------
L
I
A
T
GMD
E
--------------
L
S
A
F
S
A
----------
V
A
A
T
L
N
N
L
G
P
G
L
G
E
V
----
A
--------
L
HFGD
V
N
D
K
A
K
W
V
L
I
V
S
M
L
F
G
R
--------
L
E
I
F
T
L
----
L
I
L
L
T
P
T
--------------
F
W
R
------------------------------------------
2
HHSearch
49.09
18%
-127
- C3 -
3PJZ
1
TRKH_VIBPA
A:
[61-483]
-----------------------------------------------
K
H
E
L
K
S
R
D
G
F
-----------
L
I
V
V
L
F
W
T
V
L
G
S
A
G
S
L
P
F
L
I
A
D
-
N
P
-
N
I
S
V
T
D
A
F
F
E
S
F
S
A
L
T
T
--------
T
G
A
T
V
I
V
G
L
D
E
L
P
K
-
A
I
L
F
Y
R
Q
F
L
Q
W
F
G
G
M
G
I
I
V
L
A
V
A
I
L
P
V
L
G
-
I
G
---
G
------------------------M
T
P
R
I
A
E
T
A
K
A
L
W
Y
I
Y
L
S
L
T
I
A
C
A
V
A
F
--
W
-
L
-
A
----
G
M
T
P
F
D
A
I
S
H
S
F
-
S
T
I
A
I
-
G
G
F
S
T
H
D
A
S
M
G
Y
F
D
-------
S
Y
--
A
I
N
L
I
T
V
V
F
L
L
I
S
A
C
N
F
T
----------------
L
H
F
A
A
F
--------
A
-
S
G
GV
H
--
P
K
-------------
Y
Y
W
K
D
P
E
--
F
R
A
F
I
F
I
Q
---
V
L
-
L
F
L
V
C
F
L
L
L
L
K
-
H
H
S
-----
Y
--
T
S
P
Y
D
A
F
D
Q
A
L
F
Q
T
V
S
I
S
T
T
A
-
G
F
T
T
-
T
------
G
F
A
--
D
--
W
--
P
L
F
L
P
V
L
L
L
--------
F
S
S
F
I
G
G
C
A
G
S
T
G
G
G
M
K
V
I
R
I
L
L
L
T
L
-
Q
G
A
R
E
L
K
R
L
V
H
P
R
A
V
Y
T
I
K
V
G
G
S
A
L
P
Q
R
V
V
D
A
V
W
G
F
--------
F
S
A
Y
A
L
V
F
V
V
C
--------
M
L
G
L
I
-
A
T
------------
G
M
D
----
E
--------------
L
S
A
F
S
A
----------
V
A
A
T
L
N
N
L
G
P
G
L
G
E
V
ALHF
G
--------
D
----
V
N
D
K
A
K
W
V
L
I
V
S
M
L
F
G
R
--------
L
E
I
F
T
L
----
L
I
L
L
T
P
T
F
W
---------------------------------------------------------
32
Fugue
34.74
17%
-60
- C3 -
3W36
1
?
A:
[58-527]
--------------------------------------IE
F
D
L
D
K
D
N
Y
I
K
W
A
Q
P
T
D
E
-----------
N
A
G
Q
S
P
T
L
A
I
L
G
P
M
D
V
T
V
F
L
W
I
N
R
V
V
W
L
A
A
F
D
A
L
--
A
P
Y
H
E
T
A
--------
V
G
-----
V
Y
S
Q
I
P
R
-
R
P
S
S
E
S
A
T
N
R
N
L
N
I
A
A
L
H
A
Q
H
G
V
W
K
R
V
L
P
Q
Q
V
D
Q
L
R
E
L
M
T
A
L
GLDPSD
E
T
E
N
--
L
S
---
S
-
P
V
G
I
G
N
V
A
A
K
N
A
F
N
A
L
K
N
D
G
M
N
F
L
G
Y
E
G
R
-
K
Y
N
P
R
P
W
A
D
--
Y
T
G
Y
E
P
V
N
-
T
A
F
K
V
-
N
N
P
S
R
W
Q
P
Q
L
Q
A
H
N
ARRAGG
G
P
G
--
D
L
G
I
Y
V
T
Q
H
F
V
T
P
Q
T
A
R
T
KAHIFRDPSRF
R
I
P
R
P
E
F
S
D
H
T
--------
N
-
T
R
--
A
--
Y
K
R
S
V
D
E
I
I
D
A
----
S
A
N
L
N
D
E
R
K
A
L
A
E
I
M
E
N
KLW
G
I
-
G
H
S
S
I
V
I
--
A
N
K
Y
D
Q
N
N
E
M
G
V
--
H
G
W
C
H
W
M
L
A
H
V
L
A
T
F
E
P
-
L
I
A
-
A
W
H
H
K
T
------
R
F
D
--
A
--
V
--
R
----
P
V
T
A
--------
I
R
H
V
Y
G
N
R
K
I
R
A
W
G
G
V
G
M
G
T
V
D
I
R
A
S
-
E
W
S
S
Y
L
P
V
G
D
H
P
------
E
-------
Y
P
S
G
S
T
S
L
C
S
--------
A
T
S
Q
A
A
R
R
Y
F
D
--------
S
D
E
L
D
W
T
I
------------
N
Y
P
----
A
GSTVVEPGITPG
K
D
L
S
I
H
I
P
----------
T
W
T
D
F
T
R
T
C
A
T
S
R
V
W
----
G
--------
G
----
V
H
F
-
Q
T
T
V
D
R
T
I
D
F
G
E
Q
--------
F
G
D
L
A
H
----
E
F
V
Q
R
H
V
K
G
---------------------------------------------------------
36
Fugue
34.01
18%
-41
- C2 -
4OUA
8
?
B:
[4-557]
-------------------------------LLATVGPTG
G
V
K
N
R
L
D
I
V
D
F
V
R
D
-------------------
E
K
F
F
T
L
Y
I
R
A
L
Q
A
I
Q
D
----
K
D
Q
S
D
Y
S
S
F
F
Q
L
S
G
I
H
G
L
PFTPWAKP
K
D
T
P
T
V
P
Y
E
S
G
Y
C
T
-
H
S
Q
V
L
F
P
T
W
H
R
V
Y
V
S
I
Y
E
Q
I
L
Q
E
A
A
K
G
I
A
K
K
F
T
V
H
K
K
E
W
A
Q
-------
A
A
E
D
LR
Q
P
YWD
T
-
G
F
A
L
V
P
P
D
E
I
I
K
L
E
Q
V
K
I
T
N
Y
D
G
T
K
I
T
V
R
N
P
I
L
R
Y
S
---------
F
H
P
I
D
P
S
F
N
G
Y
P
N
F
D
T
W
K
T
T
V
R
N
P
D
------
A
D
K
KE
N
I
P
A
L
I
G
K
L
D
L
E
A
D
S
T
R
E
----------------
K
T
Y
N
M
L
--------
K
F
N
A
--
N
--
W
E
-------------
A
F
S
N
H
G
E
F
D
D
T
H
A
N
S
L
E
---
A
V
H
D
D
I
H
G
F
V
--
G
R
-
G
A
I
R
G
H
M
T
H
AL
F
A
A
F
D
P
I
F
W
L
H
H
S
N
V
D
R
-
H
L
S
-
L
W
Q
A
-
L
YPGVWV
T
Q
G
--
P
--
E
--
R
E
G
S
M
G
F
A
P
GTELNKDS
A
L
E
P
F
Y
E
T
E
D
K
P
W
T
S
V
P
L
T
D
T
A
L
L
N
Y
-
S
Y
P
D
F
D
K
V
K
G
G
T
------
P
D
L
V
R
D
Y
I
N
D
H
I
D
R
R
Y
G
I
KKSEGGKN
P
A
Q
D
L
L
S
D
F
K
G
VTHDHNED
L
K
M
F
D
W
T
I
------------
Q
A
S
----
W
KKFELDDS------
F
A
I
I
F
Y
FAADGSTNVT
K
E
N
Y
I
G
S
I
N
I
F
R
G
T
T
----
P
TNCANCRT
Q
----
D
N
L
V
Q
E
G
F
V
H
L
D
R
F
I
A
R
--------
D
L
D
-
T
F
DPQA
V
H
R
Y
L
K
E
K
K
--
L
S
Y
K
V
V
A
D
D
H
S
V
T
LKSLRIRVQGRPLHLPPGVSFPRLDKNIPIVNFDDVLDLVTG
19
HHSearch
33.48
28%
-153
- C3 -
3VOU
2
?
A:
[29-71]
---------------------------------------------------------------------
V
L
F
V
L
T
F
L
T
L
T
S
G
T
I
F
Y
S
T
V
E
----
G
L
R
P
L
D
A
L
Y
F
S
V
V
T
L
T
T
--------
V
G
D
G
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
HHSearch
33.47
15%
-133
- C3 -
3PJZ
1
TRKH_VIBPA
A:
[65-380]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
S
R
D
G
F
L
I
V
V
L
F
W
T
V
L
G
S
A
G
S
L
P
F
L
---
I
A
D
--
N
P
N
I
S
V
T
D
A
F
F
E
S
F
-
S
A
L
T
T
-
T
G
A
T
V
I
V
G
-
L
D
E
L
--------
P
K
--
A
I
L
F
Y
R
Q
F
L
Q
W
F
G
G
M
G
I
I
----------------
V
L
A
V
A
I
LPVLGIGG-----------MTP----------
R
I
A
E
T
A
K
A
L
W
Y
I
Y
L
S
L
T
---
I
A
-
C
A
V
A
F
W
L
------------
A
------
G
M
T
P
F
D
A
I
S
H
S
F
S
T
I
A
I
G
-
G
F
S
T
-
H
------
D
A
S
--
M
GY
F
D-
S
Y
A
I
N
L
I
T
V
--------
V
F
L
L
I
S
A
C
N
F
T
-----------
L
H
F
A
-
A
F
A
S
---
G
G
V
H
P
---------
K
Y
Y
W
K
D
P
E
F
R
A
F
I
F
I
--------
Q
V
---
L
L
F
L
V
C
--------
F
L
L
L
--
L
K
H
HSYTS
P
-----
Y
D
A
----
F
--------------
D
Q
A
L
F
Q
----------
T
V
S
I
S
T
T
A
G
F
T
T
T
G
F
----
A
--------
D
----
W
P
L
F
L
P
V
L
L
L
F
S
S
F
I
G
G
CAGSTGGG
M
K
V
I
R
I
----
L
L
L
T
L
Q
G
A
R
E
L
K
R
L
V
H
P
R
A
-----------------------------------------------
20
HHSearch
33.25
18%
-180
- C3 -
3LDC
4
MTHK_METTH
A:
[9-48]
-------------------------------------------------------------------------
L
V
L
A
V
I
I
Y
G
T
A
G
F
H
F
I
E
----
G
E
S
W
T
V
S
L
Y
W
T
F
V
T
I
A
T
--------
V
G
Y
G
D
Y
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
HHSearch
33.14
18%
-122
- C3 -
4J7C
1
KTRB_BACSU
I:
[35-348]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
P
P
Q
V
L
A
I
G
F
F
L
T
I
I
I
G
A
V
L
L
M
L
P
-
I
S
T
--
T
K
P
L
S
W
I
D
A
L
F
T
A
A
-
S
A
T
T
V
-
T
G
L
A
V
V
D
T
G
-
T
Q
F
--------
T
V
--
F
G
Q
T
V
I
M
G
L
I
Q
I
G
G
L
G
F
M
----------------
T
F
A
V
L
I
VMIL-------
K
I-
G
LK
E
R
MLVQEALNQPTIG
G
V
I
G
L
V
K
V
L
F
L
F
S
I
S
I
E
---
L
I
-
A
A
L
I
L
S
I
--
R
L
-
V
------
P
Q
--
Y
G
W
S
S
G
L
F
A
S
L
F
H
A
I
S
A
F
N
N
A
-
G
F
S
L
-
W
------
P
D
N
LM
S
--
Y
VG
D
P
T
V
N
L
V
I
T
--------
F
L
F
I
T
G
G
I
G
F
T
-----------
V
L
F
D
-
V
----
M
K
N
R
R
-
F
---------
K
T
F
S
L
H
T
K
L
M
L
T
G
-------------
T
L
M
L
N
A
I
A
--------
M
L
T
V
F
I
L
E
YSNPGTLGHLHI
V
D
K
----
L
--------------
W
A
S
Y
F
Q
----------
A
V
T
P
-
R
T
A
G
F
N
S
L
D
F
----
G
--------
S
----
M
R
E
G
T
I
V
F
T
L
L
L
M
F
I
G
A
GSASTASG
I
K
L
T
T
F
----
I
V
I
L
T
S
V
I
A
---------------------------------------------------------
38
Fugue
32.94
20%
-274
* C3 *
1M45
-
B:
[1-25]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
I
S
-
Q
A
I
K
Y
L
Q
N
N
I
K
G
------
F
I
I
R
Q
R
V
N
D
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
Fugue
28.72
8%
-112
* C2 *
1JS8
2
HCYG_ENTDO
A:
[1-275]
----------------------------------------
A
I
I
R
K
N
----
V
N
S
L
T
P
S
-----------
D
I
K
E
L
R
D
A
M
A
K
V
Q
A
D
-------
T
--
S
D
N
G
Y
Q
K
I
A
S
Y
H
G
I
P
--
L
--------
S
C
H
Y
E
N
G
T
A
Y
A
C
C
Q
-
H
G
-----------
M
V
T
F
P
N
W
H
R
L
L
T
K
Q
M
E
D
A
L
V
A
K
-
G
S
--------------------------------------------------
H
V
-
G
I
P
Y
W
D
W
T
T
T
-
F
A
N
L
P
V
L
V
-
T
E
E
K
D
-
N
S
F
H
------------------------------------
H
A
H
----------------
I
D
V
A
N
------------
T
--
D
--
T
T
-------------
R
S
P
R
--------
A
Q
L
F
S
---
F
F
-
Y
R
Q
I
A
L
A
--
L
E
---
Q
T
D
---------
F
C
D
F
E
I
----------------
Q
-
F
------
E
I
---
G
--
H
--
N
A
I
H
S
W
V
G
G
---------
S
S
P
--
Y
G
M
S
T
L
H
Y
T
S
Y
D
P
L
F
Y
L
H
H
S
-
N
T
D
R
I
W
S
V
W
Q
A
L
------
Q
K
Y
R
G
L
-------------------------------------------
P
Y
N
T
------------
A
N
C
----
E
--------------
I
N
K
L
V
K
----------
P
L
K
P
F
N
L
D
T
N
P
N
A
V
T
----
K
--------
A
----
H
S
T
G
A
T
S
F
--------------------------------
D
Y
H
K
--
L
G
Y
D
Y
D
N
L
N
F
H
G
M
------------------------------------------