@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu32450: (2016-07-24 )
MFTMDDLNQMDTQTLTDTLGSIFEHSSWIAERSAALRPFSSLSDLHRKMTGIVKAADRETQLDLIKKHPRLGTKKTMSDDSVREQQNAGLGKLEQQEYEEFLMLNEHYYDRFGFPFILAVKGKTKQDIHQALLARLESERETEFQQALIEIYRIARFRLADIITEKGETQMKRTMSYGKGNVFAYRTYLKPLTGVKQIPESSFAGRDNTVVGVDVTCEIGGEAFLPSFTDGDNTLVVATDSMKNFIQRHLASYEGTTTEGFLHYVAHRFLDTYSHMDTITLTGEDIPFEAMPAYEEKELSTSRLVFRRSRNERSRSVLKAERSGNTITITEQYSEIMDLQLVKVSGNSFVGFIRDEYTTLPEDGNRPLFVYLNISWQYENTNDSYASDPARYVAAEQVRDLASTVFHELETPSIQNLIYHIGCRILARFPQLTDVSFQSQNHTWDTVVEEIPGSKGKVYTEPRPPYGFQHFTVTREDAEKEKQKAAEKCRSLKA
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.-...-...330.......340.......350.......360.......370.......380------........390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490..
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MF
T
M
D
D
L
N
QM
D
T
Q
T
L
T
D
T
L
G
S
I
F
E
H
S
S
W
I
A
E
R
S
A
ALRP
F
S
S
L
S
D
L
H
R
K
M
T
G
I
V
KAADR
E
T
Q
L
D
L
I
K
KHPRLGTKKTMS
D
D
S
V
R
E
Q
Q
NAGLGK
L
E
Q
Q
E
Y
E
E
F
L
M
L
N
E
H
Y
Y
D
RFG
F
P
F
I
L
A
VKGK
T
K
Q
D
I
H
Q
A
L
L
A
R
L
E
S
E
R
E
T
E
F
Q
Q
A
L
I
E
I
Y
R
I
A
R
F
R
L
A
D
I
ITEK
G
E
T
Q
M
K
R
T
MSYGKG
N
V
F
A
Y
R
T
Y
L
K
P
L
T
G
V
K
QIPESSFAGRD
N
T
V
V
G
V
D
V
T
C
E
IGGEAFLPSFTDGD
N
T
L
V
V
A
T
D
S
M
K
N
F
I
Q
R
H
L
A
SYEGT
T
T
E
G
F
L
H
Y
V
A
H
R
F
L
D
T
YSHM
D
T
I
T
LTGEDIPFEAMPA
Y
E
E
KELS
T
S
R
L
V
F
R
RSR
N
E
R
S
R
S
V
L
K
AERS-G
N
T
-
I
T
I
T
E
Q
Y
S
EI
M
D
L
Q
L
V
K
VSGN
S
F
V
G
F
IR
D
E
YTTLPEDGN
R
P
L
F
V
Y
L
N
I
S
W
Q
YENT-------NDSYAS
D
P
A
R
Y
V
A
A
E
Q
V
R
D
L
A
S
T
V
F
HELETP
S
I
Q
N
L
I
Y
H
I
G
C
R
I
L
A
RFPQLT
D
V
S
FQSQNH
T
W
D
T
V
V
E
EIPGSKGKVYTEPRPPYGF
Q
H
F
T
V
T
R
E
D
A
E
K
E
K
Q
K
A
A
E
K
C
R
SLKA
22
PsiBlast_CBE
78.93
66%
-48
- C2 -
1J2G
3
PUCL_BACSB
C:
[7-312]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
M
Y
Y
G
K
G
D
V
F
A
Y
R
T
Y
L
K
P
L
T
G
V
R
T
I
P
E
S
P
F
S
G
R
D
H
I
L
F
G
V
N
V
K
I
S
V
G
G
T
K
L
L
T
S
F
T
K
G
D
N
S
L
V
V
A
T
D
S
M
K
N
F
I
Q
K
H
L
A
S
Y
T
G
T
T
I
E
G
F
L
E
Y
V
A
T
S
F
L
K
K
Y
S
H
I
E
K
I
S
L
I
G
E
E
I
P
F
E
T
T
F
A
V
K
N
G
N
R
A
A
S
E
L
V
F
K
K
S
R
N
E
Y
A
T
A
Y
L
N
M
V
R
N
E
D
N
T
-
L
N
I
T
E
Q
Q
S
G
L
A
G
L
Q
L
I
K
V
S
G
N
S
F
V
G
F
I
R
D
E
Y
T
T
L
P
E
D
S
N
R
P
L
F
V
Y
L
N
I
K
W
K
Y
K
N
T
-------
E
D
S
F
G
T
N
P
E
N
Y
V
A
A
E
Q
I
R
D
I
A
T
S
V
F
H
E
T
E
T
L
S
I
Q
H
L
I
Y
L
I
G
R
R
I
L
E
R
F
P
Q
L
Q
E
V
Y
F
E
S
Q
N
H
T
W
D
K
I
V
E
E
I
P
E
S
E
G
K
V
Y
T
E
P
R
P
P
Y
G
F
Q
C
F
T
V
T
Q
E
D
-----------------
1
PsiBlast_PDB
78.73
66%
-46
- C2 -
1J2G
5
PUCL_BACSB
A:
[7-312]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
M
Y
Y
G
K
G
D
V
F
A
Y
R
T
Y
L
K
P
L
T
G
V
R
T
I
P
E
S
P
F
S
G
R
D
H
I
L
F
G
V
N
V
K
I
S
V
G
G
T
K
L
L
T
S
F
T
K
G
D
N
S
L
V
V
A
T
D
S
M
K
N
F
I
Q
K
H
L
A
S
Y
T
G
T
T
I
E
G
F
L
E
Y
V
A
T
S
F
L
K
K
Y
S
H
I
E
K
I
S
L
I
G
E
E
I
P
F
E
T
T
F
A
V
K
N
G
N
R
A
A
S
E
L
V
F
K
K
S
R
N
E
Y
A
T
A
Y
L
N
M
V
R
N
E
D
N
T
-
L
N
I
T
E
Q
Q
S
G
L
A
G
L
Q
L
I
K
V
S
G
N
S
F
V
G
F
I
R
D
E
Y
T
T
L
P
E
D
S
N
R
P
L
F
V
Y
L
N
I
K
W
K
Y
K
N
T
-------
E
D
S
F
G
T
N
P
E
N
Y
V
A
A
E
Q
I
R
D
I
A
T
S
V
F
H
E
T
E
T
L
S
I
Q
H
L
I
Y
L
I
G
R
R
I
L
E
R
F
P
Q
L
Q
E
V
Y
F
E
S
Q
N
H
T
W
D
K
I
V
E
E
I
P
E
S
E
G
K
V
Y
T
E
P
R
P
P
Y
G
F
Q
C
F
T
V
T
Q
E
D
-----------------
21
PsiBlast_CBE
78.63
66%
-47
- C2 -
1J2G
4
PUCL_BACSB
D:
[7-312]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
M
Y
Y
G
K
G
D
V
F
A
Y
R
T
Y
L
K
P
L
T
G
V
R
T
I
P
E
S
P
F
S
G
R
D
H
I
L
F
G
V
N
V
K
I
S
V
G
G
T
K
L
L
T
S
F
T
K
G
D
N
S
L
V
V
A
T
D
S
M
K
N
F
I
Q
K
H
L
A
S
Y
T
G
T
T
I
E
G
F
L
E
Y
V
A
T
S
F
L
K
K
Y
S
H
I
E
K
I
S
L
I
G
E
E
I
P
F
E
T
T
F
A
V
K
N
G
N
R
A
A
S
E
L
V
F
K
K
S
R
N
E
Y
A
T
A
Y
L
N
M
V
R
N
E
D
N
T
-
L
N
I
T
E
Q
Q
S
G
L
A
G
L
Q
L
I
K
V
S
G
N
S
F
V
G
F
I
R
D
E
Y
T
T
L
P
E
D
S
N
R
P
L
F
V
Y
L
N
I
K
W
K
Y
K
N
T
-------
E
D
S
F
G
T
N
P
E
N
Y
V
A
A
E
Q
I
R
D
I
A
T
S
V
F
H
E
T
E
T
L
S
I
Q
H
L
I
Y
L
I
G
R
R
I
L
E
R
F
P
Q
L
Q
E
V
Y
F
E
S
Q
N
H
T
W
D
K
I
V
E
E
I
P
E
S
E
G
K
V
Y
T
E
P
R
P
P
Y
G
F
Q
C
F
T
V
T
Q
E
D
-----------------
23
PsiBlast_CBE
78.60
66%
-49
- C2 -
1J2G
3
PUCL_BACSB
B:
[7-312]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
M
Y
Y
G
K
G
D
V
F
A
Y
R
T
Y
L
K
P
L
T
G
V
R
T
I
P
E
S
P
F
S
G
R
D
H
I
L
F
G
V
N
V
K
I
S
V
G
G
T
K
L
L
T
S
F
T
K
G
D
N
S
L
V
V
A
T
D
S
M
K
N
F
I
Q
K
H
L
A
S
Y
T
G
T
T
I
E
G
F
L
E
Y
V
A
T
S
F
L
K
K
Y
S
H
I
E
K
I
S
L
I
G
E
E
I
P
F
E
T
T
F
A
V
K
N
G
N
R
A
A
S
E
L
V
F
K
K
S
R
N
E
Y
A
T
A
Y
L
N
M
V
R
N
E
D
N
T
-
L
N
I
T
E
Q
Q
S
G
L
A
G
L
Q
L
I
K
V
S
G
N
S
F
V
G
F
I
R
D
E
Y
T
T
L
P
E
D
S
N
R
P
L
F
V
Y
L
N
I
K
W
K
Y
K
N
T
-------
E
D
S
F
G
T
N
P
E
N
Y
V
A
A
E
Q
I
R
D
I
A
T
S
V
F
H
E
T
E
T
L
S
I
Q
H
L
I
Y
L
I
G
R
R
I
L
E
R
F
P
Q
L
Q
E
V
Y
F
E
S
Q
N
H
T
W
D
K
I
V
E
E
I
P
E
S
E
G
K
V
Y
T
E
P
R
P
P
Y
G
F
Q
C
F
T
V
T
Q
E
D
-----------------
26
PsiBlast_CBE
78.21
66%
-49
- C2 -
3WLV
6
PUCL_BACSB
B:
[2-303]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
Y
Y
G
K
G
D
V
F
A
Y
R
T
Y
L
K
P
L
T
G
V
R
T
I
P
E
S
P
F
S
G
R
D
H
I
L
F
G
V
N
V
K
I
S
V
G
G
T
K
L
L
T
S
F
T
K
G
D
N
S
L
V
V
A
T
D
S
M
K
N
F
I
Q
K
H
L
A
S
Y
T
G
T
T
I
E
G
F
L
E
Y
V
A
T
S
F
L
K
K
Y
S
H
I
E
K
I
S
L
I
G
E
E
I
P
F
E
T
T
F
A
V
K
N
G
N
R
A
A
S
E
L
V
F
K
K
S
R
N
E
Y
A
T
A
Y
L
N
M
V
R
N
E
D
N
T
-
L
N
I
T
E
Q
Q
S
G
L
A
G
L
Q
L
I
K
V
S
G
N
S
F
V
G
F
I
R
D
E
Y
T
T
L
P
E
D
S
N
R
P
L
F
V
Y
L
N
I
K
W
K
Y
K
N
T
-------
E
D
S
F
G
T
N
P
E
N
Y
V
A
A
E
Q
I
R
D
I
A
T
S
V
F
H
E
T
E
T
L
S
I
Q
H
L
I
Y
L
I
G
R
R
I
L
E
R
F
P
Q
L
Q
E
V
Y
F
E
S
Q
N
H
T
W
D
K
I
V
E
E
I
P
E
S
E
G
K
V
Y
T
E
P
R
P
P
Y
G
F
Q
C
F
T
V
T
Q
-------------------
24
PsiBlast_CBE
77.73
66%
-50
- C2 -
3WLV
5
PUCL_BACSB
D:
[2-303]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
Y
Y
G
K
G
D
V
F
A
Y
R
T
Y
L
K
P
L
T
G
V
R
T
I
P
E
S
P
F
S
G
R
D
H
I
L
F
G
V
N
V
K
I
S
V
G
G
T
K
L
L
T
S
F
T
K
G
D
N
S
L
V
V
A
T
D
S
M
K
N
F
I
Q
K
H
L
A
S
Y
T
G
T
T
I
E
G
F
L
E
Y
V
A
T
S
F
L
K
K
Y
S
H
I
E
K
I
S
L
I
G
E
E
I
P
F
E
T
T
F
A
V
K
N
G
N
R
A
A
S
E
L
V
F
K
K
S
R
N
E
Y
A
T
A
Y
L
N
M
V
R
N
E
D
N
T
-
L
N
I
T
E
Q
Q
S
G
L
A
G
L
Q
L
I
K
V
S
G
N
S
F
V
G
F
I
R
D
E
Y
T
T
L
P
E
D
S
N
R
P
L
F
V
Y
L
N
I
K
W
K
Y
K
N
T
-------
E
D
S
F
G
T
N
P
E
N
Y
V
A
A
E
Q
I
R
D
I
A
T
S
V
F
H
E
T
E
T
L
S
I
Q
H
L
I
Y
L
I
G
R
R
I
L
E
R
F
P
Q
L
Q
E
V
Y
F
E
S
Q
N
H
T
W
D
K
I
V
E
E
I
P
E
S
E
G
K
V
Y
T
E
P
R
P
P
Y
G
F
Q
C
F
T
V
T
Q
-------------------
25
PsiBlast_CBE
77.50
66%
-47
- C2 -
3WLV
7
PUCL_BACSB
C:
[2-303]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
Y
Y
G
K
G
D
V
F
A
Y
R
T
Y
L
K
P
L
T
G
V
R
T
I
P
E
S
P
F
S
G
R
D
H
I
L
F
G
V
N
V
K
I
S
V
G
G
T
K
L
L
T
S
F
T
K
G
D
N
S
L
V
V
A
T
D
S
M
K
N
F
I
Q
K
H
L
A
S
Y
T
G
T
T
I
E
G
F
L
E
Y
V
A
T
S
F
L
K
K
Y
S
H
I
E
K
I
S
L
I
G
E
E
I
P
F
E
T
T
F
A
V
K
N
G
N
R
A
A
S
E
L
V
F
K
K
S
R
N
E
Y
A
T
A
Y
L
N
M
V
R
N
E
D
N
T
-
L
N
I
T
E
Q
Q
S
G
L
A
G
L
Q
L
I
K
V
S
G
N
S
F
V
G
F
I
R
D
E
Y
T
T
L
P
E
D
S
N
R
P
L
F
V
Y
L
N
I
K
W
K
Y
K
N
T
-------
E
D
S
F
G
T
N
P
E
N
Y
V
A
A
E
Q
I
R
D
I
A
T
S
V
F
H
E
T
E
T
L
S
I
Q
H
L
I
Y
L
I
G
R
R
I
L
E
R
F
P
Q
L
Q
E
V
Y
F
E
S
Q
N
H
T
W
D
K
I
V
E
E
I
P
E
S
E
G
K
V
Y
T
E
P
R
P
P
Y
G
F
Q
C
F
T
V
T
Q
-------------------
28
PsiBlast_CBE
77.48
66%
-53
- C2 -
5AYJ
5
PUCL_BACSB
C:
[7-313]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
M
Y
Y
G
K
G
D
V
F
A
Y
R
T
Y
L
K
P
L
T
G
V
R
T
I
P
E
S
P
F
S
G
R
D
H
I
L
F
G
V
N
V
K
I
S
V
G
G
T
K
L
L
T
S
F
T
K
G
D
N
S
L
V
V
A
T
D
S
M
K
N
F
I
Q
K
H
L
A
S
Y
T
G
T
T
I
E
G
F
L
E
Y
V
A
T
S
F
L
K
K
Y
S
H
I
E
K
I
S
L
I
G
E
E
I
P
F
E
T
T
F
A
V
K
N
G
N
R
A
A
S
E
L
V
F
K
K
S
R
N
E
Y
A
T
A
Y
L
N
M
V
R
N
E
D
N
T
-
L
N
I
T
E
Q
Q
S
G
L
A
G
L
Q
L
I
K
V
S
G
N
S
F
V
G
F
I
R
D
E
Y
T
T
L
P
E
D
S
N
R
P
L
F
V
Y
L
N
I
K
W
K
Y
K
N
T
-------
E
D
S
F
G
T
N
P
E
N
Y
V
A
A
E
Q
I
R
D
I
A
T
S
V
F
H
E
T
E
T
L
S
I
Q
H
L
I
Y
L
I
G
R
R
I
L
E
R
F
P
Q
L
Q
E
V
Y
F
E
S
Q
N
H
T
W
D
K
I
V
E
E
I
---
E
G
K
V
Y
T
E
P
C
P
P
Y
G
F
Q
C
F
T
V
T
Q
E
D
L
P
---------------
29
PsiBlast_CBE
77.42
66%
-52
- C2 -
5AYJ
7
PUCL_BACSB
B:
[7-313]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
M
Y
Y
G
K
G
D
V
F
A
Y
R
T
Y
L
K
P
L
T
G
V
R
T
I
P
E
S
P
F
S
G
R
D
H
I
L
F
G
V
N
V
K
I
S
V
G
G
T
K
L
L
T
S
F
T
K
G
D
N
S
L
V
V
A
T
D
S
M
K
N
F
I
Q
K
H
L
A
S
Y
T
G
T
T
I
E
G
F
L
E
Y
V
A
T
S
F
L
K
K
Y
S
H
I
E
K
I
S
L
I
G
E
E
I
P
F
E
T
T
F
A
V
K
N
G
N
R
A
A
S
E
L
V
F
K
K
S
R
N
E
Y
A
T
A
Y
L
N
M
V
R
N
E
D
N
T
-
L
N
I
T
E
Q
Q
S
G
L
A
G
L
Q
L
I
K
V
S
G
N
S
F
V
G
F
I
R
D
E
Y
T
T
L
P
E
D
S
N
R
P
L
F
V
Y
L
N
I
K
W
K
Y
K
N
T
-------
E
D
S
F
G
T
N
P
E
N
Y
V
A
A
E
Q
I
R
D
I
A
T
S
V
F
H
E
T
E
T
L
S
I
Q
H
L
I
Y
L
I
G
R
R
I
L
E
R
F
P
Q
L
Q
E
V
Y
F
E
S
Q
N
H
T
W
D
K
I
V
E
E
I
----
G
K
V
Y
T
E
P
C
P
P
Y
G
F
Q
C
F
T
V
T
Q
E
D
L
P
---------------
2
PsiBlast_PDB
77.32
66%
-50
- C2 -
3WLV
5
PUCL_BACSB
A:
[2-303]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
Y
Y
G
K
G
D
V
F
A
Y
R
T
Y
L
K
P
L
T
G
V
R
T
I
P
E
S
P
F
S
G
R
D
H
I
L
F
G
V
N
V
K
I
S
V
G
G
T
K
L
L
T
S
F
T
K
G
D
N
S
L
V
V
A
T
D
S
M
K
N
F
I
Q
K
H
L
A
S
Y
T
G
T
T
I
E
G
F
L
E
Y
V
A
T
S
F
L
K
K
Y
S
H
I
E
K
I
S
L
I
G
E
E
I
P
F
E
T
T
F
A
V
K
N
G
N
R
A
A
S
E
L
V
F
K
K
S
R
N
E
Y
A
T
A
Y
L
N
M
V
R
N
E
D
N
T
-
L
N
I
T
E
Q
Q
S
G
L
A
G
L
Q
L
I
K
V
S
G
N
S
F
V
G
F
I
R
D
E
Y
T
T
L
P
E
D
S
N
R
P
L
F
V
Y
L
N
I
K
W
K
Y
K
N
T
-------
E
D
S
F
G
T
N
P
E
N
Y
V
A
A
E
Q
I
R
D
I
A
T
S
V
F
H
E
T
E
T
L
S
I
Q
H
L
I
Y
L
I
G
R
R
I
L
E
R
F
P
Q
L
Q
E
V
Y
F
E
S
Q
N
H
T
W
D
K
I
V
E
E
I
P
E
S
E
G
K
V
Y
T
E
P
R
P
P
Y
G
F
Q
C
F
T
V
T
Q
-------------------
34
PsiBlast_CBE
76.17
56%
-80
- C2 -
4R99
3
?
C:
[2-315]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
T
M
F
Y
G
K
G
D
V
Y
V
F
R
T
Y
A
N
P
L
K
G
L
K
Q
I
P
E
S
N
F
T
E
K
H
N
T
I
F
G
M
N
A
K
V
A
L
K
G
E
Q
L
L
T
S
F
T
E
G
D
N
S
L
V
V
A
T
D
S
M
K
N
F
I
Q
R
H
A
A
S
Y
E
G
A
T
L
E
G
F
L
Q
Y
V
C
E
A
F
L
A
K
Y
S
H
L
D
A
V
R
L
E
A
K
E
Y
A
F
D
D
I
Q
V
G
T
D
K
G
V
V
T
S
D
L
V
F
R
K
S
R
N
E
Y
V
T
A
T
V
E
V
A
R
T
-
A
S
G
-
T
E
V
V
E
Q
A
S
G
I
A
D
I
Q
L
I
K
V
S
G
S
S
F
Y
G
Y
I
I
D
E
Y
T
T
L
A
E
A
T
D
R
P
L
Y
I
F
L
N
I
G
W
A
Y
E
N
Q
-------
D
D
A
K
G
D
N
P
A
N
Y
V
A
A
E
Q
V
R
D
I
A
A
S
V
F
H
T
L
D
N
K
S
I
Q
H
L
I
Y
H
I
G
L
T
I
L
D
R
F
P
Q
L
T
E
V
N
F
G
T
N
N
R
T
W
D
T
V
V
E
G
-
D
G
F
K
G
A
V
F
T
E
P
R
P
P
F
G
F
Q
G
F
S
V
H
Q
E
D
L
A
R
E
K
A
S
A
---------
32
PsiBlast_CBE
76.09
66%
-50
- C2 -
4XFP
5
PUCL_BACSB
B:
[2-303]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
Y
Y
G
K
G
D
V
F
A
Y
R
T
Y
L
K
P
L
T
G
V
R
T
I
P
E
S
P
F
S
G
R
D
H
I
L
F
G
V
N
V
K
I
S
V
G
G
T
K
L
L
T
S
F
T
K
G
D
N
S
L
V
V
A
T
D
S
M
K
N
F
I
Q
K
H
L
A
S
Y
T
G
T
T
I
E
G
F
L
E
Y
V
A
T
S
F
L
K
K
Y
S
H
I
E
K
I
S
L
I
G
E
E
I
P
F
E
T
T
F
A
V
K
N
G
N
R
A
A
S
E
L
V
F
K
K
S
R
N
E
Y
A
T
A
Y
L
N
M
V
R
N
E
D
N
T
-
L
N
I
T
E
Q
Q
S
G
L
A
G
L
Q
L
I
K
V
S
G
N
S
F
V
G
F
I
R
D
E
Y
T
T
L
P
E
D
S
N
R
P
L
F
V
Y
L
N
I
K
W
K
Y
K
N
T
-------
E
D
S
F
G
T
N
P
E
N
Y
V
A
A
E
Q
I
R
D
I
A
T
S
V
F
H
E
T
E
T
L
S
I
Q
H
L
I
Y
L
I
G
R
R
I
L
E
R
F
P
Q
L
Q
E
V
Y
F
E
S
Q
N
H
T
W
D
K
I
---------
K
V
Y
T
E
P
R
P
P
Y
G
F
Q
C
F
T
V
T
Q
-------------------
31
PsiBlast_CBE
76.00
66%
-49
- C2 -
4XFP
5
PUCL_BACSB
C:
[2-303]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
Y
Y
G
K
G
D
V
F
A
Y
R
T
Y
L
K
P
L
T
G
V
R
T
I
P
E
S
P
F
S
G
R
D
H
I
L
F
G
V
N
V
K
I
S
V
G
G
T
K
L
L
T
S
F
T
K
G
D
N
S
L
V
V
A
T
D
S
M
K
N
F
I
Q
K
H
L
A
S
Y
T
G
T
T
I
E
G
F
L
E
Y
V
A
T
S
F
L
K
K
Y
S
H
I
E
K
I
S
L
I
G
E
E
I
P
F
E
T
T
F
A
V
K
N
G
N
R
A
A
S
E
L
V
F
K
K
S
R
N
E
Y
A
T
A
Y
L
N
M
V
R
N
E
D
N
T
-
L
N
I
T
E
Q
Q
S
G
L
A
G
L
Q
L
I
K
V
S
G
N
S
F
V
G
F
I
R
D
E
Y
T
T
L
P
E
D
S
N
R
P
L
F
V
Y
L
N
I
K
W
K
Y
K
N
T
-------
E
D
S
F
G
T
N
P
E
N
Y
V
A
A
E
Q
I
R
D
I
A
T
S
V
F
H
E
T
E
T
L
S
I
Q
H
L
I
Y
L
I
G
R
R
I
L
E
R
F
P
Q
L
Q
E
V
Y
F
E
S
Q
N
H
T
W
D
K
I
---------
K
V
Y
T
E
P
R
P
P
Y
G
F
Q
C
F
T
V
T
Q
-------------------
3
PsiBlast_PDB
75.70
66%
-51
- C2 -
4XFP
5
PUCL_BACSB
A:
[2-303]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
Y
Y
G
K
G
D
V
F
A
Y
R
T
Y
L
K
P
L
T
G
V
R
T
I
P
E
S
P
F
S
G
R
D
H
I
L
F
G
V
N
V
K
I
S
V
G
G
T
K
L
L
T
S
F
T
K
G
D
N
S
L
V
V
A
T
D
S
M
K
N
F
I
Q
K
H
L
A
S
Y
T
G
T
T
I
E
G
F
L
E
Y
V
A
T
S
F
L
K
K
Y
S
H
I
E
K
I
S
L
I
G
E
E
I
P
F
E
T
T
F
A
V
K
N
G
N
R
A
A
S
E
L
V
F
K
K
S
R
N
E
Y
A
T
A
Y
L
N
M
V
R
N
E
D
N
T
-
L
N
I
T
E
Q
Q
S
G
L
A
G
L
Q
L
I
K
V
S
G
N
S
F
V
G
F
I
R
D
E
Y
T
T
L
P
E
D
S
N
R
P
L
F
V
Y
L
N
I
K
W
K
Y
K
N
T
-------
E
D
S
F
G
T
N
P
E
N
Y
V
A
A
E
Q
I
R
D
I
A
T
S
V
F
H
E
T
E
T
L
S
I
Q
H
L
I
Y
L
I
G
R
R
I
L
E
R
F
P
Q
L
Q
E
V
Y
F
E
S
Q
N
H
T
W
D
K
I
---------
K
V
Y
T
E
P
R
P
P
Y
G
F
Q
C
F
T
V
T
Q
-------------------
33
PsiBlast_CBE
75.39
56%
-83
- C2 -
4R99
3
?
D:
[2-315]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
T
M
F
Y
G
K
G
D
V
Y
V
F
R
T
Y
A
N
P
L
K
G
L
K
Q
I
P
E
S
N
F
T
E
K
H
N
T
I
F
G
M
N
A
K
V
A
L
K
G
E
Q
L
L
T
S
F
T
E
G
D
N
S
L
V
V
A
T
D
S
M
K
N
F
I
Q
R
H
A
A
S
Y
E
G
A
T
L
E
G
F
L
Q
Y
V
C
E
A
F
L
A
K
Y
S
H
L
D
A
V
R
L
E
A
K
E
Y
A
F
D
D
I
Q
V
G
T
D
K
G
V
V
T
S
D
L
V
F
R
K
S
R
N
E
Y
V
T
A
T
V
E
V
A
R
T
-
A
S
G
-
T
E
V
V
E
Q
A
S
G
I
A
D
I
Q
L
I
K
V
S
G
S
S
F
Y
G
Y
I
I
D
E
Y
T
T
L
A
E
--
D
R
P
L
Y
I
F
L
N
I
G
W
A
Y
E
N
Q
-------
D
D
A
K
G
D
N
P
A
N
Y
V
A
A
E
Q
V
R
D
I
A
A
S
V
F
H
T
L
D
N
K
S
I
Q
H
L
I
Y
H
I
G
L
T
I
L
D
R
F
P
Q
L
T
E
V
N
F
G
T
N
N
R
T
W
D
T
V
V
E
G
T
D
G
F
K
G
A
V
F
T
E
P
R
P
P
F
G
F
Q
G
F
S
V
H
Q
E
D
L
A
R
E
K
A
S
A
---------
27
PsiBlast_CBE
75.21
66%
-55
- C2 -
5AYJ
4
PUCL_BACSB
D:
[6-309]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
M
Y
Y
G
K
G
D
V
F
A
Y
R
T
Y
L
K
P
L
T
G
V
R
T
I
P
E
S
P
F
S
G
R
D
H
I
L
F
G
V
N
V
K
I
S
V
G
G
T
K
L
L
T
S
F
T
K
G
D
N
S
L
V
V
A
T
D
S
M
K
N
F
I
Q
K
H
L
A
S
Y
T
G
T
T
I
E
G
F
L
E
Y
V
A
T
S
F
L
K
K
Y
S
H
I
E
K
I
S
L
I
G
E
E
I
P
F
E
T
T
F
A
V
------
A
S
E
L
V
F
K
K
S
R
N
E
Y
A
T
A
Y
L
N
M
V
R
N
E
D
N
T
-
L
N
I
T
E
Q
Q
S
G
L
A
G
L
Q
L
I
K
V
S
G
N
S
F
V
G
F
I
R
D
E
Y
T
T
L
P
E
D
S
N
R
P
L
F
V
Y
L
N
I
K
W
K
Y
K
N
T
-------
E
D
S
F
G
T
N
P
E
N
Y
V
A
A
E
Q
I
R
D
I
A
T
S
V
F
H
E
T
E
T
L
S
I
Q
H
L
I
Y
L
I
G
R
R
I
L
E
R
F
P
Q
L
Q
E
V
Y
F
E
S
Q
N
H
T
W
D
K
I
V
E
E
I
----
G
K
V
Y
T
E
P
C
P
P
Y
G
F
Q
C
F
T
V
T
Q
-------------------
30
PsiBlast_CBE
75.00
66%
-51
- C2 -
4XFP
5
PUCL_BACSB
D:
[2-303]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
Y
Y
G
K
G
D
V
F
A
Y
R
T
Y
L
K
P
L
T
G
V
R
T
I
P
E
S
P
F
S
G
R
D
H
I
L
F
G
V
N
V
K
I
S
V
G
G
T
K
L
L
T
S
F
T
K
G
D
N
S
L
V
V
A
T
D
S
M
K
N
F
I
Q
K
H
L
A
S
Y
T
G
T
T
I
E
G
F
L
E
Y
V
A
T
S
F
L
K
K
Y
S
H
I
E
K
I
S
L
I
G
E
E
I
P
F
E
T
T
F
A
V
K
N
G
N
R
A
A
S
E
L
V
F
K
K
S
R
N
E
Y
A
T
A
Y
L
N
M
V
R
N
E
D
N
T
-
L
N
I
T
E
Q
Q
S
G
L
A
G
L
Q
L
I
K
V
S
G
N
S
F
V
G
F
I
R
D
E
Y
T
T
L
P
E
D
S
N
R
P
L
F
V
Y
L
N
I
K
W
K
Y
K
N
T
-------
E
D
S
F
G
T
N
P
E
N
Y
V
A
A
E
Q
I
R
D
I
A
T
S
V
F
H
E
T
E
T
L
S
I
Q
H
L
I
Y
L
I
G
R
R
I
L
E
R
F
P
Q
L
Q
E
V
Y
F
E
S
Q
N
H
T
W
D
K
I
---------
K
V
Y
T
E
P
R
P
P
Y
G
F
Q
C
F
T
V
T
Q
-------------------
35
PsiBlast_CBE
74.69
56%
-83
- C2 -
4R99
3
?
B:
[2-315]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
T
M
F
Y
G
K
G
D
V
Y
V
F
R
T
Y
A
N
P
L
K
G
L
K
Q
I
P
E
S
N
F
T
E
K
H
N
T
I
F
G
M
N
A
K
V
A
L
K
G
E
Q
L
L
T
S
F
T
E
G
D
N
S
L
V
V
A
T
D
S
M
K
N
F
I
Q
R
H
A
A
S
Y
E
G
A
T
L
E
G
F
L
Q
Y
V
C
E
A
F
L
A
K
Y
S
H
L
D
A
V
R
L
E
A
K
E
Y
A
F
D
D
I
Q
V
G
T
D
K
G
V
V
T
S
D
L
V
F
R
K
S
R
N
E
Y
V
T
A
T
V
E
V
A
R
T
-
A
S
G
-
T
E
V
V
E
Q
A
S
G
I
A
D
I
Q
L
I
K
V
S
G
S
S
F
Y
G
Y
I
I
D
E
Y
T
-----
T
D
R
P
L
Y
I
F
L
N
I
G
W
A
Y
E
N
Q
-------
D
D
A
K
G
D
N
P
A
N
Y
V
A
A
E
Q
V
R
D
I
A
A
S
V
F
H
T
L
D
N
K
S
I
Q
H
L
I
Y
H
I
G
L
T
I
L
D
R
F
P
Q
L
T
E
V
N
F
G
T
N
N
R
T
W
D
T
V
V
E
G
T
D
G
F
K
G
A
V
F
T
E
P
R
P
P
F
G
F
Q
G
F
S
V
H
Q
E
D
L
A
R
E
K
A
S
A
---------
5
PsiBlast_PDB
73.99
56%
-89
- C2 -
4R99
3
?
A:
[2-315]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
T
M
F
Y
G
K
G
D
V
Y
V
F
R
T
Y
A
N
P
L
K
G
L
K
Q
I
P
E
S
N
F
T
E
K
H
N
T
I
F
G
M
N
A
K
V
A
L
K
G
E
Q
L
L
T
S
F
T
E
G
D
N
S
L
V
V
A
T
D
S
M
K
N
F
I
Q
R
H
A
A
S
Y
E
G
A
T
L
E
G
F
L
Q
Y
V
C
E
A
F
L
A
K
Y
S
H
L
D
A
V
R
L
E
A
K
E
Y
A
F
D
D
I
Q
V
G
T
D
K
G
V
V
T
S
D
L
V
F
R
K
S
R
N
E
Y
V
T
A
T
V
E
V
A
R
T
-
A
S
G
-
T
E
V
V
E
Q
A
S
G
I
A
D
I
Q
L
I
K
V
S
G
--
F
Y
G
Y
I
I
D
E
Y
T
T
L
-----
R
P
L
Y
I
F
L
N
I
G
W
A
Y
E
N
Q
-------
D
D
A
K
G
D
N
P
A
N
Y
V
A
A
E
Q
V
R
D
I
A
A
S
V
F
H
T
L
D
N
K
S
I
Q
H
L
I
Y
H
I
G
L
T
I
L
D
R
F
P
Q
L
T
E
V
N
F
G
T
N
N
R
T
W
D
T
V
V
E
G
T
D
G
F
K
G
A
V
F
T
E
P
R
P
P
F
G
F
Q
G
F
S
V
H
Q
E
D
L
A
R
E
K
A
S
A
---------
45
HHSearch
73.24
65%
-48
* C2 *
4XFP
5
PUCL_BACSB
A:
[2-303]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
Y
Y
G
K
G
D
V
F
A
Y
R
T
Y
L
K
P
L
T
G
V
R
T
I
P
E
S
P
F
S
G
R
D
H
I
L
F
G
V
N
V
K
I
S
V
G
G
T
K
L
L
T
S
F
T
K
G
D
N
S
L
V
V
A
T
D
S
M
K
N
F
I
Q
K
H
L
A
S
Y
T
G
T
T
I
E
G
F
L
E
Y
V
A
T
S
F
L
K
K
Y
S
H
I
E
K
I
S
L
I
G
E
E
I
P
F
E
T
T
F
A
V
K
N
G
N
R
A
A
S
E
L
V
F
K
K
S
R
N
E
Y
A
T
A
Y
L
N
M
V
R
N
-
E
D
N
T
L
N
I
T
E
Q
Q
S
G
L
A
G
L
Q
L
I
K
V
S
G
N
S
F
V
G
F
I
R
D
E
Y
T
T
L
P
E
D
S
N
R
P
L
F
V
Y
L
N
I
K
W
K
Y
K
N
T
E
D
S
F
GTN
P
E
N
Y
V
-
A
A
------
E
Q
I
R
D
I
A
T
S
V
F
H
E
T
E
T
L
S
I
Q
H
L
I
Y
L
I
G
R
R
I
L
E
R
F
P
Q
L
Q
E
V
Y
F
E
S
Q
N
H
T
W
D
K
I
---------
K
V
Y
T
E
P
R
P
P
Y
G
F
Q
C
F
T
V
T
Q
-------------------