@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu35070: (2016-07-29 )
MTGMVTERRSVHFIAEALTENCREIFERRRHVLVGISPFNSRFSEDYIYRLIGWAKAQFKSVSVLLAGHEAANLLEALGTPRGKAERKVRKEVSRNRRFAERALVAHGGDPKAIHTFSDFIDNKAYQLLRQEVEHAFFEQPHFRHACLDMSREAIIGRARGVSLMMEEVSEDMLNLAVEYVIAELPFFIGAPDILEVEETLLAYHRPWKLGEKISNHEFSICMRPNQGYLIVQEMAQMLSEKRITSEG
Atome Classification :
(20 SA)
---------------------------------------.........10.-.......--20........30....---------....40..-......50.....-...-60-........------70..----......80........---90...-.---.----------...100.......110..--.----....-..120.----........-----130.......140.-......150...---..----.-.160-........170.-----.....-.180----------.......190--........200.......210----------.......220.......230--.......240......----------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------------------MTGMVTER
R
S
V
H
-
F
I
A
E
A
L
T
--
E
N
C
R
E
I
F
E
RRR
H
V
L
V
G
---------ISPFNSRF-
S
E
D
Y
I
Y
R
L
I
G
W
A
K-
A
Q
F
-
K
S
-
V
S
V
L
LAG
H
------
E
A
A
N
----
L
L
E
A
LGTPR
G
K
A
E
R
K
V
---
R
K
E
V
S
-R---N----------
R
R
F
A
E
R
A
L
VAHGGD--
P
K
--
A
----
I
H
T
F
-
S
D
F
--
I
----
D
N
K
A
Y
Q
L
L
-----
R
Q
E
V
E
H
A
F
FEQPH
F
-
R
H
A
C
L
D
M
S
R
E
A
I
---IG----R-AR-
G
-
V
S
L
M
M
E
E
V
S
E
D
M
-----
L
N
L
A
V
-
E
Y
V
I
----------
A
EL
P
F
FIGA---
P
D
I
L
E
V
E
E
T
L
L
A
YHRPWKLGE----------KISNH
E
F
S
I
C
MRPNQ
G
Y
L
I
V
--
Q
E
M
A
Q
M
L
S
E
KRITSEG----------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_CBE
91.69
70%
-146
- C6 -
3OQH
1
CDLS_BACLD
B:
[11-235]
-------------------------------------------------
Q
L
-
F
K
T
E
T
L
T
--
Q
N
C
N
E
I
L
K
R
R
R
H
V
L
V
G
---------
I
S
P
F
N
S
R
F
-
S
E
D
Y
I
H
R
L
I
A
W
A
V
-
R
E
F
-
Q
S
-
V
S
V
L
L
A
G
K
------
E
A
A
N
----
L
L
E
A
L
G
T
P
H
G
K
A
E
R
K
V
---
R
K
E
V
S
-
R
---
N
----------
R
R
F
A
E
K
A
L
E
A
H
G
G
N
--
P
E
--
D
----
I
H
T
F
-
S
D
F
--
A
----
N
Q
T
A
Y
R
N
L
-----
R
M
E
V
E
A
A
F
F
D
Q
T
H
F
-
R
N
A
C
L
E
M
S
H
A
A
I
---
L
G
----
R
-
A
R
-
G
-
T
R
M
D
V
V
E
V
S
A
D
M
-----
L
E
L
A
V
-
E
Y
V
I
----------
A
E
L
P
F
F
I
A
A
---
P
D
I
L
G
V
E
E
T
L
L
A
Y
H
R
P
W
K
L
G
E
----------
Q
I
S
R
N
E
F
A
V
K
M
R
P
N
Q
G
Y
L
M
V
--
S
E
A
-----------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
91.09
70%
-157
- C6 -
3OQJ
1
CDLS_BACLD
A:
[13-234]
----------------------------------------------------
F
K
T
E
T
L
T
--
Q
N
C
N
E
I
L
K
R
R
R
H
V
L
V
G
---------
I
S
P
F
N
S
R
F
-
S
E
D
Y
I
H
R
L
I
A
W
A
V
-
R
E
F
-
Q
S
-
V
S
V
L
L
A
G
K
------
E
A
A
N
----
L
L
E
A
L
G
T
P
H
G
K
A
E
R
K
V
---
R
K
E
V
S
-
R
---
N
----------
R
R
F
A
E
K
A
L
E
A
H
G
G
N
--
P
E
--
D
----
I
H
T
F
-
S
D
F
--
A
----
N
Q
T
A
Y
R
N
L
-----
R
M
E
V
E
A
A
F
F
D
Q
T
H
F
-
R
N
A
C
L
E
M
S
H
A
A
I
---
L
G
----------------
V
E
V
S
A
D
M
-----
L
E
L
A
V
-
E
Y
V
I
----------
A
E
L
P
F
F
I
A
A
---
P
D
I
L
G
V
E
E
T
L
L
A
Y
H
R
P
W
K
L
G
E
----------
Q
I
S
R
N
E
F
A
V
K
M
R
P
N
Q
G
Y
L
M
V
--
S
E
------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_CBE
90.90
70%
-150
- C6 -
3OQJ
1
CDLS_BACLD
B:
[13-234]
----------------------------------------------------
F
K
T
E
T
L
T
--
Q
N
C
N
E
I
L
K
R
R
R
H
V
L
V
G
---------
I
S
P
F
N
S
R
F
-
S
E
D
Y
I
H
R
L
I
A
W
A
V
-
R
E
F
-
Q
S
-
V
S
V
L
L
A
G
K
------
E
A
A
N
----
L
L
E
A
L
G
T
P
H
G
K
A
E
R
K
V
---
R
K
E
V
S
-
R
---
N
----------
R
R
F
A
E
K
A
L
E
A
H
G
G
N
--
P
E
--
D
----
I
H
T
F
-
S
D
F
--
A
----
N
Q
T
A
Y
R
N
L
-----
R
M
E
V
E
A
A
F
F
D
Q
T
H
F
-
R
N
A
C
L
E
M
S
H
A
A
I
---
L
G
-------
R
-
G
-
T
R
M
D
V
V
E
V
S
A
D
M
-----
L
E
L
A
V
-
E
Y
V
I
----------
A
E
L
P
F
F
I
A
A
---
P
D
I
L
G
V
E
E
T
L
L
A
Y
H
R
P
W
K
L
G
E
----------
Q
I
S
R
N
E
F
A
V
K
M
R
P
N
Q
G
Y
L
M
V
--
S
E
------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
90.07
70%
-144
- C6 -
3OQI
4
CDLS_BACLD
A:
[13-234]
----------------------------------------------------
F
K
T
E
T
L
T
--
Q
N
C
N
E
I
L
K
R
R
R
H
V
L
V
G
---------
I
S
P
F
N
S
R
F
-
S
E
D
Y
I
H
R
L
I
A
W
A
V
-
R
E
F
-
Q
S
-
V
S
V
L
L
A
G
K
------
E
A
A
N
----
L
L
E
A
L
G
T
P
H
G
K
A
E
R
K
V
---
R
K
E
V
S
-
R
---
N
----------
R
R
F
A
E
K
A
L
E
A
H
G
G
N
--
P
E
--
D
----
I
H
T
F
-
S
D
F
--
A
----
N
Q
T
A
Y
R
N
L
-----
R
M
E
V
E
A
A
F
F
D
Q
T
H
F
-
R
N
A
C
L
E
M
S
H
A
A
I
---
L
G
----
R
-
A
R
-
G
-
T
R
M
D
V
V
E
V
S
A
D
M
-----
L
E
L
A
V
-
E
Y
V
I
----------
A
E
L
P
F
F
I
A
A
---
P
D
I
L
G
V
E
E
T
L
L
A
Y
H
R
P
W
K
L
G
E
----------
Q
I
S
R
N
E
F
A
V
K
M
R
P
N
Q
G
Y
L
M
V
--
S
E
------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
89.86
70%
-158
- C6 -
3OQH
-
CDLS_BACLD
A:
[12-235]
--------------------------------------------------
L
-
F
K
T
E
T
L
T
--
Q
N
C
N
E
I
L
K
R
R
R
H
V
L
V
G
---------
I
S
P
F
N
S
R
F
-
S
E
D
Y
I
H
R
L
I
A
W
A
V
-
R
E
F
-
Q
S
-
V
S
V
L
L
A
G
K
------
E
A
A
N
----
L
L
E
A
L
G
T
P
H
G
K
A
E
R
K
V
---
R
K
E
V
S
-
R
---
N
----------
R
R
F
A
E
K
A
L
E
A
H
G
G
N
--
P
E
--
D
----
I
H
T
F
-
S
D
F
--
A
----
N
Q
T
A
Y
R
N
L
-----
R
M
E
V
E
A
A
F
F
D
Q
T
H
F
-
R
N
A
C
L
E
M
S
H
A
A
I
---
L
----------------
V
V
E
V
S
A
D
M
-----
L
E
L
A
V
-
E
Y
V
I
----------
A
E
L
P
F
F
I
A
A
---
P
D
I
L
G
V
E
E
T
L
L
A
Y
H
R
P
W
K
L
G
E
----------
Q
I
S
R
N
E
F
A
V
K
M
R
P
N
Q
G
Y
L
M
V
--
S
E
A
-----------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
89.01
69%
-157
- C- -
3S7T
-
CDLS_BACLD
A:
[12-235]
--------------------------------------------------
L
-
F
K
T
E
T
L
T
--
Q
N
C
N
E
I
L
K
R
R
R
H
V
L
V
G
---------
I
S
P
F
N
S
R
F
-
S
E
D
Y
I
H
R
L
I
A
W
A
V
-
R
E
F
-
Q
S
-
V
S
V
L
L
A
G
K
------
E
A
A
N
----
L
L
E
A
L
G
T
P
H
G
K
A
E
R
K
V
---
R
K
E
V
S
-
R
---
N
----------
R
R
F
A
E
K
A
L
E
A
H
G
G
N
--
P
E
--
D
----
I
H
T
F
-
S
D
F
--
A
----
N
Q
T
A
Y
R
N
L
-----
R
M
E
V
E
A
A
F
F
D
Q
T
H
F
-
R
N
A
C
L
E
M
S
H
A
A
I
---
L
-----------------
V
E
V
S
A
D
M
-----
L
E
L
A
V
-
E
Y
V
I
----------
A
E
L
P
F
F
I
A
A
---
P
D
I
L
G
V
E
E
T
L
L
A
Y
H
R
P
W
K
L
G
E
----------
Q
I
S
R
N
E
F
A
V
K
M
R
P
N
Q
G
Y
L
M
V
--
S
E
A
-----------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
86.30
71%
-100
- C6 -
3OQI
4
CDLS_BACLD
A:
[13-234]
----------------------------------------------------
F
K
T
E
T
L
T
--
Q
N
C
N
E
I
L
K
R
R
R
H
V
L
V
G
---------
I
S
P
F
N
S
R
F
-
S
E
D
Y
I
H
R
L
I
A
W
A
V
-
R
E
F
-
Q
S
-
V
S
V
L
L
A
G
K
------
E
A
A
N
----
L
L
E
A
L
G
T
P
H
G
K
A
E
R
K
V
---
R
K
E
V
S
-
R
---
N
----------
R
R
F
A
E
K
A
L
E
A
H
G
G
N
--
P
E
--
D
----
I
H
T
F
-
S
D
F
--
A
----
N
Q
T
A
Y
R
N
L
-----
R
M
E
V
E
A
A
F
F
D
Q
T
H
F
-
R
N
A
C
L
E
M
S
H
A
A
I
---
L
G
----
R
-
A
R
G
T
R
M
D
V
--
V
E
V
S
A
D
M
-----
L
E
L
A
V
-
E
Y
V
I
----------
A
E
L
P
F
F
I
A
A
---
P
D
I
L
G
V
E
E
T
L
L
A
Y
H
R
P
W
K
L
G
E
----------
Q
I
S
R
N
E
F
A
V
K
M
R
P
N
Q
G
Y
L
M
V
--
S
E
------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
60.56
29%
-48
- C6 -
4Q24
1
CLPS_STRNR
A:
[16-233]
-------------------------------------------------------
E
I
L
G
--
D
R
S
R
L
I
R
Q
R
G
E
H
A
L
I
G
---------
I
C
A
G
N
S
Y
F
-
S
Q
K
N
T
V
M
L
L
Q
W
A
G
-
Q
R
F
-
E
R
-
T
D
V
V
Y
V
D
T
------
H
I
D
E
----
M
L
I
A
D
G
R
S
A
Q
E
A
E
R
S
V
---
K
R
T
L
K
-
D
---
L
----------
R
R
R
L
R
R
S
L
E
S
V
G
D
H
--
A
E
R
F
R
----
V
R
S
L
-
S
E
L
--
Q
----
E
T
P
E
Y
R
A
V
-----
R
E
R
T
D
R
A
F
E
E
D
A
E
F
-
A
T
A
C
E
D
M
V
R
A
V
V
---
M
N
----
R
P
G
D
-
G
-
V
G
-----
I
S
A
E
H
-----
L
R
A
G
L
-
N
Y
V
L
----------
A
E
A
P
L
F
A
D
S
---
P
G
V
F
S
V
P
S
S
V
L
C
Y
H
I
D
T
P
I
T
A
----------
F
L
S
R
R
E
T
G
F
R
A
A
E
G
Q
A
Y
V
V
V
R
P
Q
-------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
57.58
29%
-37
- C6 -
3OQV
4
CLPS_STRNR
A:
[28-237]
---------------------------------------------------------------------
R
G
E
H
A
L
I
G
---------
I
S
A
G
N
S
Y
F
-
S
Q
K
N
T
V
M
L
L
Q
W
A
G
-
Q
R
F
-
E
R
-
T
D
V
V
Y
V
D
T
------
H
I
D
E
----
M
L
I
A
D
G
R
S
A
Q
E
A
E
R
S
V
---
K
R
T
L
K
-
D
---
L
----------
R
R
R
L
R
R
S
L
E
S
V
G
D
H
--
A
E
R
F
R
----
V
R
S
L
-
S
E
L
--
Q
----
E
T
P
E
Y
R
A
V
-----
R
E
R
T
D
R
A
F
E
E
D
A
E
F
-
A
T
A
C
E
D
M
V
R
A
V
V
---
M
N
----
R
P
G
D
-
G
-
V
G
-----
I
S
A
E
H
-----
L
R
A
G
L
-
N
Y
V
L
----------
A
E
A
P
L
F
A
D
S
---
P
G
V
F
S
V
P
S
S
V
L
C
Y
H
I
D
T
P
I
T
A
----------
F
L
S
R
R
E
-
G
F
R
A
A
E
G
Q
A
Y
V
V
V
R
P
Q
E
L
A
D
---------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
55.97
28%
-36
- C6 -
3OQV
4
CLPS_STRNR
A:
[28-237]
---------------------------------------------------------------------
R
G
E
H
A
L
I
G
---------
I
S
A
G
N
S
Y
F
-
S
Q
K
N
T
V
M
L
L
Q
W
A
G
-
Q
R
F
-
E
R
-
T
D
V
V
Y
V
D
T
------
H
I
D
E
----
M
L
I
A
D
G
R
S
A
Q
E
A
E
R
S
V
---
K
R
T
L
K
-
D
---
L
----------
R
R
R
L
R
R
S
L
E
S
V
G
D
H
AE
R
F
--
R
----
V
R
S
L
-
S
E
L
--
Q
----
E
T
P
E
Y
R
A
V
-----
R
E
R
T
D
R
A
F
E
E
D
A
E
F
-
A
T
A
C
E
D
M
V
R
A
V
V
---
M
N
----
R
-
P
G
D
G
-
V
-----
G
I
S
A
E
H
-----
L
R
A
G
L
-
N
Y
V
L
----------
A
E
A
P
L
F
A
D
S
---
P
G
V
F
S
V
P
S
S
V
L
C
Y
H
I
D
T
P
I
T
A
----------
F
L
S
R
R
E
-
G
F
R
A
A
E
G
Q
A
Y
V
V
V
--
R
P
Q
E
L
A
D
-------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
55.47
27%
-67
- C6 -
2X9Q
-
CDTS_MYCTU
A:
[64-281]
----------------------------------------------------
F
L
V
R
P
F
T
--
Q
Q
C
Q
I
I
H
T
E
G
D
H
A
V
I
G
---------
V
S
P
G
N
S
Y
F
-
S
R
Q
R
L
R
D
L
G
L
W
G
L
-
T
N
F
-
D
R
-
V
D
F
V
Y
T
D
V
------
H
V
A
E
----
S
Y
E
A
L
G
D
S
A
I
E
A
R
R
K
A
---
V
K
N
I
R
-
G
---
V
----------
R
--
A
K
I
T
T
T
V
N
E
L
D
--
P
A
--
G
AR
L
C
V
R
P
M
-
S
E
F
--
Q
----
S
N
E
A
Y
R
E
L
-----
H
A
D
L
L
T
R
L
K
D
D
E
D
M
-
R
A
V
C
Q
D
L
V
R
R
F
L
S
T
K-----------
G
-
A
T
A
T
Q
E
Q
V
C
M
D
-------------
Y
I
C
----------
A
E
A
P
L
F
L
D
T
---
P
A
I
L
G
V
P
S
S
L
N
C
Y
H
Q
S
L
P
L
A
E
----------
M
L
Y
A
R
G
S
G
L
R
A
S
R
N
Q
G
H
A
I
V
----------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
49.94
25%
6
* C6 *
2X9Q
-
CDTS_MYCTU
A:
[49-284]
-------------------------------------FQ
L
G
R
R
I
P
E
A
T
A
Q
E
G
F
L
V
R
P
F
T
--
Q
Q
C
Q
I
I
H
T
E
G
D
H
A
V
I
G
---------
V
S
P
G
N
S
Y
F
-
S
R
Q
R
L
R
D
L
G
L
W
G
L
-
T
N
F
-
D
R
-
V
D
F
V
Y
T
D
V
------
H
V
A
E
----
S
Y
E
A
L
G
D
S
A
I
E
A
R
R
K
A
---
V
K
N
I
R
-
G
---
V
----------
R
A
K
I
T
T
T
V
N
E
L
D
P
A
G-
A
R
--
L
----
C
V
R
P
M
S
E
F
--
Q
----
S
N
E
A
Y
R
E
L
-----
H
A
D
L
L
T
R
L
K
D
D
E
-
D
M
R
A
V
C
Q
D
L
V
R
R
F
L
---
S
T
----
K
-
G
------------
A
T
A
T
-----
Q
E
Q
V
C
M
D
Y
I
C
----------
A
E
A
P
L
F
L
D
T
---
P
A
I
L
G
V
P
S
S
L
N
C
Y
H
Q
S
L
P
L
A
E
M
---------
L
Y
A
R
-
G
S
G
L
R
A
S
R
N
Q
G
H
A
I
V
--
T
P
D
-----------------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
44.16
18%
-138
- C- -
4YNH
-
SAS5_CAEEL
A:
[229-250]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
-----
L
T
I
I
E
Q
R
L
R
S
D
P
M
F
-
R
Q
Q
I
D
N
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
32.55
13%
-61
- C6 -
1D2R
-
SYW_GEOSE
A:
[1-326]
----------------------------------------------------------------------
M
K
T
I
F
S
G
---------
I
Q
P
S
-
G
V
I
T
I
G
N
Y
I
G
A
L
R
Q
F
V
E
-
L
Q
H
--
E
-
Y
N
C
Y
F
C
I
V
------
D
Q
H
A
----
I
T
V
----------
W
Q
D
---
P
H
E
L
R
-
Q
---
N
----------
I
R
R
L
A
A
L
Y
L
A
V
G
I
D
--
P
T
Q
A
T
----
L
F
I
Q
-
S
E
V
--
P
-------
A
H
A
Q
A
-----
A
W
M
L
Q
C
I
V
Y
I
G
E
L
E
-
R
M
T
Q
F
K
E
K
S
A
G
A
---
A
A
----
A
-
A
A
-
G
-
L
L
T
Y
P
P
L
M
A
A
D
I
-----
L
L
Y
-----
N
T
----------
D
I
V
P
V
G
E
D
Q
---
K
Q
H
I
E
L
T
R
D
L
A
E
R
F
N
K
-
R
Y
G
E
----------
L
F
T
I
P
-
E
A
R
I
P
K
V
G
A
R
I
M
S
L
--
V
D
P
T
K
K
M
S
K
S
D
P
N
P
K
A
YITLLDD
A
K
T
I
E
K
K
I
K
S
AVTDSEGTIRYDKEAK
P
G
I
S
N
L
L
N
I
Y
S
T
L
S
GQS
I
E
E
L
E
R
Q
Y
EGKG
Y
G
V
F
K
A
D
L
A
Q
V
V
I
E
T
L
R
P
I
Q
E
R
Y
H
H
W
M
E
SE
E
L
D
R
V
L
D
E
G
A
E
K
A
N
R
V
A
S
E
M
V
R
K
M
E
Q
A
M
GLGR
35
Fugue
30.17
22%
-77
- C6 -
1IXS
-
A:
[13-62]
----------------------------------------------------------------------------------------------------------------------
E
S
E
A
A
E
------
E
A
V
M
----
A
L
A
A
L
G
F
K
E
A
Q
A
R
A
V
V
---
L
D
L
L
A
-
Q
---
N
----------
P
K
A
R
A
Q
D
L
I
K
E
A
L
K
--
R
L
--
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
26.72
13%
-30
- C6 -
2CYC
1
SYY_PYRHO
A:
[33-138]
----------------------------------------------------------------------
P
L
Q
H
Y
I
G
---------
F
E
I
S
G
Y
I
H
-
L
G
T
G
L
M
A
G
A
K
I
A
D
F
Q
K
A
G
I
K
-
T
R
V
F
L
A
D
W
------
H
S
W
I
----
N
D
K
-
L
G
G
D
L
----
E
V
I
---
Q
E
V
A
L
K
Y
---
F
----------
K
V
G
M
E
K
S
I
E
V
M
G
G
D
PK
K
V
--
E
----
F
V
L
A
-
S
E
I
--
L
----
E
K
G
D
Y
W
Q
T
-----
V
I
D
I
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
Fugue
25.67
14%
22
- C6 -
2TS1
-
?
?:
[1-227]
-------------------------------M
D
L
L
A
E
L
Q
W
R
G
L
V
N
Q
T
T
D
E
D
-
G
L
R
K
L
L
N
--
E
E
-------
R
V
T
L
Y
C
G
---------
F
D
P
T
A
D
S
L
-
H
I
G
H
L
A
T
I
L
T
M
R
R
-
F
Q
Q
-
A
G
H
R
P
I
A
L
V
G
----------
G
----
A
T
G
L
I
G
D
P
S
G
K
K
S
E
R
T
L
N
A
K
E
T
V
E
-
A
---
W
----------
S
A
R
I
K
E
Q
L
-
G
R
F
L
D
--
F
E
--
A
----
D
G
N
P
-
A
K
I
--
K
----
N
N
Y
D
W
I
G
P
-----
L
D
V
I
T
F
L
R
D
V
G
K
H
F
-
S
V
N
Y
M
M
A
K
E
S
V
Q
---
S
R
----
I
-
E
T
-
G
-
I
S
-----
F
T
E
F
S
-----
Y
M
M
L
Q
-
A
Y
D
F
----------
L
R
L
Y
E
T
E
G
C
---
R
L
Q
I
G
G
S
D
Q
W
G
N
I
T
A
G
L
E
L
I
R
----------
K
T
K
G
R
A
F
G
L
T
I
P
L
--------------------
V
T
K
A
D
----------------------------------------------------------------------------------------------------------------------------
33
Fugue
25.50
17%
34
* C4 *
4UX8
-
GFRA1_RAT
C:
[25-343]
---------------DRLDCVKASDQCLKEQSCSTKYRT
L
R
Q
C
V
A
G
K
E
T
N
F
-
S
L
T
S
G
L
E
AK
D
E
C
R
S
A
M
E
A
L
K
Q
K
S
L
Y
---------
N
C
R
C
K
R
G
M
-
K
K
E
K
N
C
L
R
I
Y
W
S
M
-
Y
Q
S
-
K
G
--
N
N
C
L
D
A
A
------
K
A
C
N
----
L
D
D
T
C
K
K
Y
R
S
A
Y
I
T
P
C
---
T
T
S
M
S
-
N
EVC
N
----------
R
R
K
C
H
K
A
L
R
Q
F
F
D
K
--
V
P
--
A
----
K
H
S
Y
-
G
M
L
--
F
CSCR
D
I
A
C
T
E
R
R
-----
R
Q
T
I
V
P
V
C
S
Y
E
E
R
E
-
R
P
N
C
L
S
L
Q
D
S
C
K
TNY
I
C
----
R
-
S
R
-
L
-
A
D
F
F
T
N
C
Q
P
E
S
R
SVSNC
L
K
E
N
Y
-
A
D
C
L
----------
L
A
Y
S
G
L
I
G
T
VMT
P
N
Y
V
D
S
S
S
L
S
V
A
---
P
W
C
D
C
S
----------
N
-
S
G
N
D
L
E
D
C
L
K
F
L
N
F
F
K
D
N
--
T
C
L
K
N
A
I
Q
A
F
G
---
N
G
----------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
25.29
25%
-11
- C3 -
4GEO
2
MK14_HUMAN
A:
[216-319]
-------------------------------------------------------------------------------------------------------
V
G
C
I
M
-
A
E
L
-
L
T
-
G
R
T
L
F
P
G
T
------
D
A
A
D
Q
L
K
L
I
L
R
L
V
G
T
P
G
A
E
L
L
K
K
I
---
S
S
E
S
A
-
R
---
N
A
I
Q
S
LTQMPK
M
N
F
A
N
---
V
F
I
G
A
N
--
P
L
--
A
----
V
D
L
L
-
E
K
M
L
V
L
----
D
S
D
K
R
I
T
A
-----
A
Q
A
L
A
H
A
Y
F
A
Q
Y
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
Fugue
24.93
16%
-40
- C5 -
4O6M
13
?
A:
[29-370]
M
R
L
A
Y
V
K
N
H
EIYGEKLLGLT
L
R
E
R
I
E
K
T
L
Q
R
A
G
F
D
V
R
F
F
D
E
L
S
L
E
E
A
E
D
Y
L
-
I
I
L
E
P
V
L
--
I
L
E
R
D
L
L
L
E
G
R
K
I
L
V
S
DGFTV
G
Y
F
F
G
G
D
F
R
T
V
F
-
D
G
N
L
Q
S
S
I
E
K
Y
L
S
-
L
N
N
-
L
E
-
S
Y
E
I
W
A
I
K
L
S
NDN
L
K
T
A
E
----
K
L
L
L
S
S
L
I
D
G
W
I
A
R
E
I
---
N
R
K
V
S
-
L
---
R
----------
I
S
---
R
L
L
A
D
T
S
V
T
--
P
N
--
Q
----
I
T
V
F
-
S
F
F
--
L
----
S
L
V
G
S
A
L
F
L
L
NS
Y
L
T
T
L
L
A
G
V
I
I
Q
L
H
S
-
I
I
D
G
C
D
G
E
I
A
R
L
---
K
F
MES
K
Y
-
G
A
-
W
-
L
D
G
V
L
D
R
Y
S
D
F
I
-----
I
V
F
S
I
-
T
Y
V
L
S
A
S
NP
V
Y
W
I
I
G
F
L
A
A
F
A
S
L
---
M
I
A
Y
T
G
D
K
F
V
A
A
Y
M
R
T
Y
S
P
E
G
FAIPIT
R
D
F
R
L
L
I
I
F
A
C
S
V
V
N
L
P
S
L
A
L
V
I
I
--
A
L
L
G
N
F
E
A
L
R
R
I
V
A
L
R
SY--------------------------------------------------------------------------------------------------------------------------