@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu35340: (2016-07-30 )
MVTRITGLASGMDIDDIVSKLMQTERAPLDKLTQKKQTLEWQRDSYREVNSKIKELQDYMSKNTLTYPSTYQSKTVTSSNESVLTATGSVSAPNSSSTVEVASLATAATYKANNYTGYTQGDYNLAFNVVAPGETTAKTVNISVTSADTIDNVISKLNSSDLGVSAFKDKIWNGTEYVETIAFSSKATGAGGSIQAADSATADFMSGQLGFSLDADNKLTAYKEGTNAKVTINGFEMEKLTNNFTVNGVTYSIKNTTAATGPVTTSVSTDVDGIYNQIKEFVDKYNELVDSLNEKLKEEKYRDYTPLTSEQKEAMSDKEVELWEEKAKSGLLRNDSSISTGTNQMRTDFYTQVNADGKTYQLTEFGITTSSAYQLRGHLEINEEKLKAKIAEDPQGVANLFTSGTNDSNYSDKGIMKRITNTLRSTVKSIEAKAGNSTMGASSYSIGKNLNSISTEITDMQDRLNTIENRYYSKFSAMDSAIQKMNEQASYLSQLLVQ
Atome Classification :
(20 SA)
---.........10........20........-----30........-40........50........60....---....70........80........90......---..100.......110......-------.120----........130.......140......---------.150.......160.....-..170........180.......190.......200.......210.......220.......230....----...240.......250.---......260.......270..---.----------....280.......290.......---300....-...310.......320..-.....330.......340.......350.......360.......370..-------.....---.380.......390..---.....400..-----.....410......---------.420..----.....430.......440.....------..450.......460.....----..--470.--......480.......490------........---------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---MV
T
R
I
TGLASGM
D
I
D
D
I
V
S
K
L
M
Q
TERA
P
L
-----
D
K
L
T
Q
K
K
Q
T
L
-
E
W
Q
R
D
S
Y
R
E
V
N
S
K
I
K
E
L
Q
D
Y
M
SKNTL---TYPSTYQSKTVTSSNE
S
V
L
T
ATGSVSAPNSSS---
T
V
E
V
A
S
L
A
T
A
A
T
Y
KANNYTGY-------TQG-----D
Y
N
L
A
F
N
V
VAPGET
T
A
K
T
V
N
I
S
V
TS
A
D
---------
T
I
D
N
V
I
S
K
LNSSDL
G
V
S
A
F
-
K
D
K-IWN
G
T
E
Y
V
E
T
I
AFSSKATGAGG
S
I
Q
AADSA
T
A
D
FMSGQLG
F
S
LDADNK
L
T
A
Y
KEGTN
A
K
V
T
ING
F
E
----
M
E
K
LTNN
F
T
VN
G
V
T
Y
S
I---KNTTAATGP
V
T
T
SVST
D
V
D
G
I
---
Y
----------
N
Q
I
K
E
F
V
D
K
Y
N
E
L
V
D
S
L
N
E
K
L
K
E
E
---
K
YRDYTP-L
T
S
E
Q
K
E
AMS
D
K
E
V
E
L
W
E
-
E
K
A
KSGLLRNDSSISTGTNQ
M
R
T
D
F
Y
T
Q
VNADG
K
T
Y
Q
L
T
E
FGITTS
S
-
A
Y
-------
Q
L
R
G
H
---
L
E
I
N
E
E
K
L
K
A
K
IAE
D
P
---
Q
G
V
A
N
L
F
TSG-----TNDSNY
S
D
K
G
I
M
K
R
---------
I
T
N
T
L
R
----
S
T
V
K
S
I
E
AKAGNSTMGASSYSIG------KN
L
N
S
I
S
T
E
I
T
D
M
Q
D
R
L
N
T
I
----
E
N
--
R
Y
Y
S
--
K
F
S
A
M
D
S
A
I
Q
K
M
N
E
Q
A
S
--------
Y
L
S
Q
L
LVQ---------
37
Fugue
61.13
17%
63
- C2 -
2BVL
8
TOXB_PEPDI
A:
[1-543]
--------
M
S
L
V
N
R
K
Q
L
E
K
M
A
N
V
R
F
R
T
Q
E
D
E
Y
-----
V
A
I
L
D
A
L
E
E
Y
H
N
M
S
E
N
T
V
V
E
K
Y
L
K
L
K
D
I
N
S
L
T
D
I
C
I
D
---
T
Y
K
K
S
G
R
N
K
A
L
K
K
F
K
E
Y
L
V
T
E
V
L
E
L
K
N
N
N
L
T
P
VEK
N
L
H
F
V
W
I
G
G
Q
I
N
D
T
A
I
N
Y
I
N
Q
-------
W
K
D
V
N
SD
Y
N
V
N
V
F
Y
D
S
N
A
F
L
I
N
T
L
K
K
T
V
V
E
S
A
I
N
D
---------
T
L
E
S
F
R
E
N
L
N
D
P
R
F
D
Y
N
K
F
F
R
K
R
-
M
E
I
I
Y
D
K
Q
K
N
F
I
N
Y
Y
K
A
Q
R
E
E
N
P
E
L
I
I
D
D
I
V
K
T
Y
L
S
N
E
Y
S
---
K
E
I
D
E
L
N
T
Y
I
E
E
S
L
N
K
I
T
Q
N
S
G
N
DVRN
F
G
E
F
K
N
G
E
S
F
N
L
Y
E
Q
E
L
VER
W
N
L
A
A
A
S
D
I
L
R
I
S
A
L
K
E
I
G
G
M
---
Y
L
D
VDMLPGIQ
P
D
L
F
E
S
I
E
K
P
S
S
V
T
V
D
F
W
E
M
T
K
L
E
A
I
M
K
Y
K
E
Y
I
P
E
Y
T
S
E
H
F
D
M
L
D
E
E
V
Q
S
S
F
E
-
S
V
L
A
S
K
--
S
D
K
S
E
I
F
S
S
L
G
D
M
E
A
S
P
L
E
V
K
I
A
F
N
S
K
G
I
I
N
Q
G
L
I
S
V
K
D
-
S
Y
C
S
N
L
I
V
K
Q
I
E
N
R
---
Y
K
I
L
N
N
S
L
N
P
A
I
S
E
D
N
D
F
N
T
T
T
N
T
F
I
D
S
I
-----
M
A
E
A
N
A
D
N
G
R
F
M
M
E
---------
L
G
K
Y
L
R
VGFF
P
D
V
K
T
T
I
N
L
S
G
P
E
A
Y
A
A
A
Y
Q
D
L
L
M
FKEGS
M
N
I
H
L
I
E
A
D
L
R
N
F
E
I
S
K
T
N
I
SQST
E
Q
--
E
M
A
S
--
L
W
S
F
D
D
A
R
A
K
A
Q
F
E
E
Y
K
--------
R
N
Y
F
E
G
A
L
---------
39
Fugue
60.16
17%
60
- C2 -
4ZH0
-
?
A:
[27-527]
-------------------------------------
Q
D
L
S
D
R
Y
E
S
L
-
N
N
L
L
N
R
Y
S
T
L
N
T
L
I
K
L
S
A
D
P
S
A
I
N
A
V
---
R
E
N
L
G
A
S
A
K
N
L
I
G
D
K
A
N
-------------
S
P
---
A
Y
Q
A
V
L
L
A
I
N
A
A
V
G
F
W
N
V
V
G
Y
V
T
Q
C
G
G
N
A
N
G
-----
Q
K
S
I
S
S
K
T
I
F
N
N
E
P
G
Y
R
S
T
S
I
T
C
S
L
N
G
HSPGYYGPM
S
I
E
N
F
K
K
L
N
E
A
Y
Q
I
L
Q
T
A
L
-
K
R
G
-
L
P
A
L
K
E
N
N
G
K
V
N
V
T
Y
T
Y
T
C
S
G
D
G
N
N
N
C
S
S
Q
V
T
G
---------------
V
N
N
Q
K
D
G
T
K
T
K
I
Q
T
I
D
------
G
K
S
V
T
T
T
I
S
S
K
V
V
D
S
R
A
---
D
G
N
T
--
T
G
V
S
Y
T
E
I
T
N
K
L
E
G
V
---
P
----------
D
S
A
Q
A
L
L
A
Q
A
S
T
L
I
N
T
I
N
N
A
C
P
Y
F
---
H
A
P
K
F
S
T
-
T
T
G
K
I
C
G
A
F
S
E
E
I
S
A
I
Q
K
M
I
T
D
A
Q
E
L
V
N
Q
T
S
V
I
N
E
H
E
Q
T
T
P
V
G
-----
N
N
N
G
K
P
F
N
P
F
T
D
A
S
F
A
Q
G
M
L
A
-------
N
A
S
A
Q
A
K
M
L
N
L
A
E
Q
V
G
Q
A
I
N
P
E
R
L
---
S
G
T
F
Q
N
F
V
K
G
FLATC
N
N
P
S
Q
G
S
A
P
G
T
V
T
T
QTFASGCAY
V
G
Q
T
I
T
----
N
L
K
N
S
I
A
H
F
G
T
Q
E
Q
Q
I
Q
Q
A
E
N
I
A
------
D
T
L
V
N
F
K
S
R
Y
S
E
L
G
N
T
Y
N
S
I
----
T
T
--
A
L
S
N
IP
N
A
Q
S
L
Q
N
A
V
S
K
K
N
N
P
Y
S
PQGID
T
N
Y
Y
L
N
Q
N
S
Y
N
Q
I
Q
T
I
N
Q
E
L
40
Fugue
57.39
16%
65
- C1 -
4O2X
-
MALE_ECOLI
A:
[5-483]
EG
K
L
V
I
W
I
N
G
D
K
G
Y
N
G
L
A
E
V
G
K
K
F
E
K
D
T
G
I
K
V
T
V
E
H
P
D
K
L
E
E
K
F
P
Q
V
-
A
A
T
G
D
G
P
D
I
I
F
W
A
H
D
R
F
G
G
Y
A
Q
S
G
L
L
A
E
I
T
P
D
K
A
F
Q
D
K
L
Y
P
F
T
W
D
A
V
R
Y
N
G
K
L
I
A
Y
P
---
I
---
A
V
E
A
L
S
L
I
Y
N
K
D
L
L
P
N
P
P
K
T
W
-------
E
E
--------------
I
P
A
L
D
K
E
L
K
A
K
G
K
S
A
L
M
F
N
---------
L
Q
E
P
Y
F
T
W
P
L
I
A
A
D
G
G
Y
A
F
-
K
Y
E
---
N
G
K
Y
D
I
K
D
V
G
V
D
N
-----
A
G
A
K
A
G
L
T
F
L
V
D
L
I
K
N
K
H
M
N
A
D
T
D
Y
S
I
A
E
A
A
F
N
K
G
E
T
A
M
T
I
N
G
P
W
A
----
W
S
N
I
D
T
S
K
V
N
Y
G
V
T
V
L
P
---
T
F
K
G
Q
P
S
K
P
F
V
G
V
L
S
A
G
I
N
A
A
SPN
K
----------
E
L
A
K
E
F
L
E
N
Y
L
-
L
T
D
E
G
L
E
A
V
N
K
D
---
K
P
L
G
A
V
A
-
L
K
S
Y
E
E
E
L
A
K
D
P
R
I
A
A
T
M
-
E
N
A
Q
K
G
E
I
M
P
N
I
P
Q
M
S
A
F
W
Y
A
V
R
T
A
V
I
N
A
A
S
G
R
Q
T
--------
V
D
E
A
-
L
A
-------
A
A
Q
T
N
---
A
A
A
N
L
E
K
I
K
K
L
R
N
V
I
T
---
S
A
W
K
V
I
L
Y
--------
N
D
D
I
H
N
----
F
T
Y
---------
V
T
D
V
I
V
----
K
V
V
G
Q
I
S
-
K
A
K
A
H
T
I
T
V
E
A
H
S
T
G
----------------------
Q
A
L
I
----
L
S
--
T
W
K
S
--
K
A
E
K
Y
C
Q
E
L
Q
Q
N
G
L
T
V
S
--------
I
I
H
E
S
------------
36
Fugue
51.94
14%
-18
- C2 -
4O5J
3
?
A:
[27-400]
-----------------
L
K
N
L
N
E
K
Y
E
Q
L
S
Q
Y
L
-----
N
Q
V
A
S
L
K
Q
S
I
-
Q
N
A
N
N
-
I
E
L
V
N
S
S
L
N
Y
L
K
S
F
T
N
N
N
Y
N
---
S
---------------------
T
T
Q
S
P
I
F
N
A
V
---
Q
A
V
I
T
S
V
L
G
F
W
S
L
Y
A
G
N
Y
F
T
F
-------
F
V
G
-----------
K
K
V
D
S
G
Q
P
A
S
V
Q
G
N
P
P
F
---
K
---------
T
I
I
E
N
C
S
G
I
E
N
C
A
M
D
Q
T
T
Y
--
D
K
-
M
K
K
L
A
E
D
L
Q
A
A
Q
T
N
S
A
T
K
G
N
N
L
C
A
L
S
G
C
A
A
T
S
N
P
P
N
S
T
V
S
N
A
L
N
L
A
Q
Q
L
M
D
L
I
A
N
T
K
T
A
M
M
W
K
N
I
V
----
I
S
G
V
S
N
T
-------------------
S
G
A
I
T
S
T
N
Y
P
T
Q
Y
A
V
---
F
----------
N
N
I
K
A
M
I
P
I
L
Q
Q
A
V
T
L
S
Q
S
N
H
T
L
S
---
A
---------
S
L
Q
A
Q
A
T
G
S
Q
T
N
P
K
F
A
-
K
D
I
Y
T
-
F
A
Q
N
Q
K
Q
V
I
S
Y
A
Q
D
I
F
N
L
F
N
S
---
I
P
A
E
Q
Y
K
Y
L
E
---------------------------------------------------------------------------------------
K
----
A
Y
L
K
I
P
N
A
G
S
T
P
T
N
P
Y
R
Q
V
V
N
L
N
------
Q
E
V
Q
T
I
K
N
N
V
S
Y
Y
G
N
R
V
D
A
A
----
L
S
V
A
R
D
V
Y
--
N
L
K
S
N
Q
A
E
I
V
T
A
Y
N
D
A
K
--------
T
L
S
E
E
I
S
K
LPH------
21
HHSearch
38.65
17%
-358
- C3 -
2XDJ
-
YBGF_ECOLI
A:
[26-67]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
Q
Q
L
S
D
N
Q
------
S
D
I
D
S
L
R
G
Q
I
Q
E
N
Q
Y
Q
L
N
Q
V
----
V
E
--
R
Q
K
Q
--
I
L
L
Q
I
D
S
L
----------------------------------
14
PsiBlast_PDB
34.07
50%
-56
- C3 -
2JWZ
-
UBI4P_YEAST
A:
[9-34]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
K
T
I
T
L
E
V
E
S
S
D
---------
T
I
D
N
V
K
S
K
I
Q
D
K
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
33.27
56%
-92
- C3 -
3L10
-
UBI4P_YEAST
B:
[9-34]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
K
T
I
T
L
E
V
E
S
S
D
---------
T
I
D
N
V
K
S
K
I
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
33.00
50%
-74
- C3 -
1OTR
-
UBI4P_YEAST
B:
[9-34]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
K
T
I
T
L
E
V
E
S
S
D
---------
T
I
D
N
V
K
S
K
I
Q
D
K
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
32.36
50%
-2
- C3 -
4Q5E
-
B:
[9-34]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
K
T
I
T
L
E
V
E
S
S
D
---------
T
I
D
N
V
K
S
K
I
Q
D
K
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
31.38
50%
-5
- C3 -
4Q5H
-
B:
[9-34]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
K
T
I
T
L
E
V
E
S
S
D
---------
T
I
D
N
V
K
S
K
I
Q
D
K
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
30.86
50%
8
- C3 -
4II3
-
RL402_SCHPO
B:
[29-54]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
K
T
I
T
L
E
V
E
S
S
D
---------
T
I
D
N
V
K
S
K
I
Q
D
K
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
30.04
42%
-7
- C3 -
1FI0
1
VPR_HV1RH
A:
[1-21]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
P
Y
N
E
W
T
L
E
L
L
E
E
L
K
S
E
---
A
V
R
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
29.98
15%
-
* C3 *
2AKF
1
COR1A_MOUSE
A:
[3-29]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
L
E
------
E
D
V
R
N
L
N
A
I
V
Q
K
L
Q
E
R
L
D
R
L
----
E
E
--
T
V
----------------------------------------------
4
PsiBlast_PDB
29.86
35%
-24
- C3 -
2OJR
1
UBC_HUMAN
A:
[19-65]
----------------------------------------------------------------------------------------------------------------------------
Y
I
D
T
N
N
D
G
W
-------
I
E
G
-----
D
E
L
L
A
M
Q
I
F
V
K
-
T
L
T
G
K
T
I
T
L
E
V
E
P
S
D
---------
T
I
E
N
V
K
A
K
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
29.84
56%
-12
- C3 -
3L0W
-
UBI4P_YEAST
B:
[9-34]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
K
T
I
T
L
E
V
E
S
S
D
---------
T
I
D
N
V
K
S
K
I
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
Fugue
29.47
30%
-55
* C2 *
1M3W
1
?
A:
[2-30]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
G
G
E
I
---
W
----------
K
L
H
E
E
F
L
K
K
F
E
E
L
L
K
L
H
E
E
R
L
K
K
M
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
29.37
50%
38
- C3 -
3CMM
-
UBI4P_YEAST
B:
[9-34]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
K
T
I
T
L
E
V
E
S
S
D
---------
T
I
D
N
V
K
S
K
I
Q
D
K
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
28.93
39%
-2
- C3 -
2KDI
-
UBI4P_YEAST
A:
[18-59]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
K
T
I
T
L
E
V
E
S
S
D
---------
T
I
D
N
V
K
S
K
I
Q
D
K
E
-
G
I
P
P
D
-
Q
Q
R
L
I
W
A
G
K
Q
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
28.52
50%
51
- C3 -
4NNJ
-
UBI4P_YEAST
B:
[12-37]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
K
T
I
T
L
E
V
E
S
S
D
---------
T
I
D
N
V
K
S
K
I
Q
D
K
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
28.42
50%
49
- C3 -
4HCN
-
UBI4P_YEAST
B:
[31-56]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
K
T
I
T
L
E
V
E
S
S
D
---------
T
I
D
N
V
K
S
K
I
Q
D
K
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------