@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu35620: (2016-07-30 )
MRSYIKVLTMCFLGLILFVPTALADNSVKRVGGSNRYGTAVQISKQMYSTASTAVIVGGSSYADAISAAPLAYQKNAPLLYTNSDKLSYETKTRLKEMQTKNVIIVGGTPAVSSNTANQIKSLGISIKRIAGSNRYDTAARVAKAMGATSKAVILNGFLYADAPAVIPYAAKNGYPILFTNKTSINSATTSVIKDKGISSTVVVGGTGSISNTVYNKLPSPTRISGSNRYELAANIVQKLNLSTSTVYVSNGFSYPDSIAGATLAAKKKQSLILTNGENLSTGARKIIGSKNMSNFMIIGNTPAVSTKVANQLKNPVVGETIFIDPGHGDQDSGAIGNGLLEKEVNLDIAKRVNTKLNASGALPVLSRSNDTFYSLQERVNKAASAQADLFLSIHANANDSSSPNGSETYYDTTYQAANSKRLAEQIQPKLAANLGTRDRGVKTAAFYVIKYSKMPSVLVETAFITNASDASKLKQAVYKDKAAQAIHDGTVSYYR
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320......---.330.....---------------------.--.-340.......350......-.-360---...--.-.-...370---..--.....380.......390.......-400...-...--------------------------------..-410.----..------.----.----------------------------..----------------------------------420..----....--------.430...-.-----.-..-.-----.440-------------------------.-.------..-...450.......460.......470.......480.......490....------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
R
S
Y
I
K
V
L
T
M
C
F
L
G
L
I
L
F
VP
T
A
LADN
S
V
K
RVGGSNRY
G
T
A
V
Q
I
S
K
Q
M
YSTA
S
T
A
V
I
VGGS
S
Y
A
D
A
ISAAP
L
A
YQKNA
P
L
L
Y
TNSDKLS
Y
E
T
K
T
R
L
K
E
MQTK
N
V
I
I
VGGTPAVSSN
T
A
N
Q
I
K
S
LG
I
S
I
K
RIAGSNR
Y
D
T
A
A
R
V
A
K
A
MGATS
K
A
V
I
L
N
G
F
LYADAPAV
I
P
YAAKNG
Y
P
I
L
F
TNKTSINS
A
T
T
S
V
I
KDKGIS
S
T
V
V
VGGTGS
I
S
N
T
V
Y
NKLPSPTRISGS
N
R
Y
E
L
A
A
N
I
V
Q
K
LNLST
S
T
V
Y
V
SNGFSY
P
D
S
IAG
A
T
L
AAKKK
Q
S
L
I
L
TNGENL
S
T
G
A
R
K
I
IGSKNMS
N
F
M
I
IGNTPA
V
S
T
K
V
A
N
Q
LKNPVVG
E
T
I
F
IDPGH---GDQDSGAIG---------------------N--
G
-
L
L
E
K
EVN
L
D
I
A
K
RVNTKLN-A-S-G---AL
P
--
V
-
L
-SRSND
T
---
F
Y
--
S
L
Q
E
R
V
N
K
AASAQA
D
L
F
L
S
I
HANAN-DS-SSP-NGS--------------------------------E
T
-
Y
Y
D
T
----
T
Y------Q----A----------------------------A
N
----------------------------------
S
K
R
L
A
----
E
Q
I
Q
--------
P
K
--
L
A
A
-N-----L-GT-R-----DRG
V
-------------------------
K
-
T
------
A
A
-
F
Y
V
I
K
YSKM
P
S
V
L
V
E
T
A
FITNAS
D
A
S
K
L
K
Q
A
V
Y
K
D
K
A
A
Q
A
I
HDGTVSYYR------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
73.70
38%
27
- C4 -
4BIN
2
AMIC_ECOLI
A:
[171-394]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
R
P
I
V
I
M
L
D
P
G
H
---
G
G
E
D
S
G
A
V
G
---------------------
K
Y-
K
-
T
R
E
K
D
V
V
L
Q
I
A
R
R
L
R
S
L
I
E
-
K
-
E
G
N
---
M
K
V
--
Y
-
M
-
T
R
N
E
D
I
---
F
I
--
P
L
Q
V
R
V
A
K
A
Q
K
Q
R
A
D
L
F
V
S
I
H
A
D
A
F
-
T
S
-
R
Q
P
-
S
G
S
--------------------------------
S
V
-
F
A
L
S
----
T
K
------
G
AT--
S
T
A
A
K
Y
L
A
Q
T
Q
N
A
S
DLIGGVSD
M
V
Q
S
L
T
I
A
D
----------------------------------
S
L
K
F
G
----
K
A
V
L
--------
N
K
--
L
G
K
-
I
-----
N
-
K
L
-
H
-----
K
N
Q
V
-------------------------
E
-
Q
------
A
G
-
F
A
V
L
K
A
P
D
I
P
S
I
L
V
E
T
A
F
I
S
N
V
E
E
E
R
K
L
K
T
A
T
F
Q
Q
E
V
A
E
S
I
L
A
G
I
K
A
Y
F
A
------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
72.18
43%
27
- C4 -
5EMI
4
?
A:
[3-179]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
L
L
V
V
I
D
P
G
H
---
G
G
K
D
S
G
A
P
G
---------------------
L
G-
G
-
L
L
E
K
D
V
I
L
P
I
G
K
R
V
A
A
I
L
E
-
Q
-
H
-
G
---
V
Q
A
--
V
-
L
-
T
R
D
A
D
F
---
F
V
--
E
L
Q
G
R
V
E
I
A
E
R
V
N
A
T
A
F
V
S
I
H
A
N
S
V
-
D
N
R
P
D
V
-
N
G
L
--------------------------------
E
V
-
Y
Y
Y
D
-----------------------------------------------
S
----------------------------------
G
Y
A
L
A
----
E
V
V
R
--------
N
T
--
I
L
Q
-
N
-----
I
D
T
I
-
K
-----
N
R
G
T
-------------------------
R
-
K
------
A
R
-
F
Y
V
L
R
K
S
S
M
P
S
I
L
V
E
T
G
Y
M
T
G
R
E
D
N
P
R
L
A
S
R
E
Y
Q
N
Q
M
A
E
A
I
A
R
G
I
L
K
Y
L
Q
------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
71.95
43%
17
- C4 -
5EMI
4
?
A:
[7-177]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
V
I
D
P
G
H
---
G
G
K
D
S
G
A
P
G
L--------------------
G
--
G
-
L
L
E
K
D
V
I
L
P
I
G
K
R
V
A
A
I
L
E
-
Q
-
H
-
G
---
V
Q
A
--
V
-
L
-
T
R
D
A
D
F
---
F
V
--
E
L
Q
G
R
V
E
I
A
E
R
V
N
A
T
A
F
V
S
I
H
A
N
S
V
-
D
N
-
R
P
D
V
N
G
L
--------------------------------
E
V
Y
Y
Y
D
S
----
G
Y
------
A
------------------------------------------------------------------------
L
A
----
E
V
V
R
--------
N
T
--
I
L
Q
-
N
-----
I
-
D
T
I
K
-----
N
R
G
T
-------------------------
R
-
K
------
A
R
-
F
Y
V
L
R
K
S
S
M
P
S
I
L
V
E
T
G
Y
M
T
G
R
E
D
N
P
R
L
A
S
R
E
Y
Q
N
Q
M
A
E
A
I
A
R
G
I
L
K
Y
--------------------------------------------------------------------------------------------------------------------------------------------
42
Fugue
71.50
25%
27
- C4 -
1XOV
6
?
A:
[12-326]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
M
S
N
Y
S
M
S
R
G
H
---
S
D
K
C
V
G
A
E
D
------------------------
I
-
L
S
E
I
K
E
A
E
K
V
L
N
A
A
S
D
E
L
K
-
R
-
E
-
G
H
N
V
K
T
F
--
I
-
D
-
R
T
S
T
T
Q
---
S
A
--
N
L
N
K
I
V
N
W
H
N
A
N
P
A
D
V
H
I
S
V
H
L
N
A
G
-----
K
G
-
T
G
V
--------------------------------
E
V
-
W
Y
Y
A
------------
G
----
D
----------------------------
E
K
----------------------------------
G
R
K
L
A
----
V
E
I
S
--------
A
K
--
M
A
K
-
A
-----
L
-
G
L
-
P
-----
N
R
G
A
-------------------------
K
-
A
------
T
K
D
L
R
F
L
N
S
T
K
G
T
A
V
L
L
E
V
C
F
V
D
R
K
E
D
A
N
A
I
H
K
S
G
M
Y
D
K
L
G
I
A
I
A
E
G
L
T
G
K
T
V
AAKNPN
R
H
S
G
A
V
V
DSVPMLSKMDFKSSPI
K
M
Y
K
AG
S
S
L
L
V
Y
E
H
N
KY
W
Y
K
A
Y
I
ND
K
L
C
Y
I
Y
KSF
C
I
S
N
G
K
KDAKG
R
I
K
V
R
I
K
SAKD
L
R
I
P
V
W
NNTKLNS
G
K
I
K
W
Y
S
PG
T
K
L
S
W
Y
D
NKKG
Y
L
E
L
W
Y
EKD
G
W
Y
Y
T
A
NYFLK
4
PsiBlast_PDB
70.51
32%
39
- C4 -
4BIN
2
AMIC_ECOLI
A:
[172-393]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
P
I
V
---
I
M
L
D
P
G
H
---
G
G
E
D
S
G
A
V
G
---------------------
K
Y-
K
-
T
R
E
K
D
V
V
L
Q
I
A
R
R
L
R
S
L
I
E
-
K
-
E
-
G
---
N
M
K
--
V
Y
M
-
T
R
N
E
D
I
---
F
I
--
P
L
Q
V
R
V
A
K
A
Q
K
Q
R
A
D
L
F
V
S
I
H
A
D
A
F
-
T
S
-
R
Q
P
-
S
G
S
S
V
F
A
L
S
TKGATS
T
A
A
K
Y
L
A
Q
T
Q
N
A
S
DLIGGVS-------------D
M
V
Q
S
L
T
----
I
----------------------------
A
D
----------------------------------
S
L
K
F
G
----
K
A
V
L
--------
N
K
--
L
G
K
-
I
-----
N
-
K
L
-
H
-----
K
N
Q
V
-------------------------
E
-
Q
------
A
G
-
F
A
V
L
K
A
P
D
I
P
S
I
L
V
E
T
A
F
I
S
N
V
E
E
E
R
K
L
K
T
A
T
F
Q
Q
E
V
A
E
S
I
L
A
G
I
K
A
Y
F
-------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
65.95
32%
39
- C4 -
3NE8
8
?
A:
[3-225]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
F
R
V
V
L
D
P
G
H
---
G
G
I
D
G
G
A
R
G
---------------------
V
T-
G
-
I
L
E
K
D
V
T
L
A
F
A
R
A
L
R
D
E
L
Q
-
K
-
G
-
S
H--
T
I
V
--
A
-
L
-
T
R
D
S
D
I
---
F
L
--
R
L
S
E
R
V
K
K
A
Q
E
F
D
A
D
L
F
I
S
I
H
A
D
T
I
-
D
V
-
H
S
L
-
R
G
A
--------------------------------
T
V
-
Y
T
I
S
----
D
E
------
A
----
S
D---------------------------
A
I
A
K
S
L
A
E
S
E
N
K
VDLLDGLPKED
I
L
L
D
L
T
R
R
E
T
H
A
F
S
I
N
F
A
----
N
N
V
V
--------
S
N
--
L
S
K
S
H
-----
I
-
N
L
-
I
-----
N
N
P
H
-------------------------
R
-
Y
------
A
D
-
F
Q
V
L
K
A
P
D
V
P
S
V
L
I
E
I
G
Y
L
S
N
K
E
D
E
K
L
L
N
N
P
Q
W
R
K
Q
M
A
A
S
I
A
Y
S
I
R
Q
F
A
E
------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
64.78
39%
31
- C4 -
1JWQ
1
?
A:
[2-175]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
V
V
I
D
A
G
H
---
G
A
K
D
S
G
A
V
G
IS-------------------
R
--
K
-
N
Y
E
K
T
F
N
L
A
M
A
L
K
V
E
S
I
L
K
-
Q
-
N
-
P
---
K
L
E
--
V
V
L
-
T
R
S
D
D
T
---
F
L
--
E
L
K
Q
R
V
K
V
A
E
N
L
K
A
N
V
F
V
S
I
H
A
N
S
S
-
G
S
-
S
A
S
-
N
G
T
--------------------------------
E
T
-
Y
Y
--------------
Q
----
R
----------------------------
S
A
----------------------------------
S
K
A
F
A
----
N
V
M
H
--------
K
Y
--
F
A
P
-
A
-----
T
-
G
L
-
T
-----
D
R
G
I
-------------------------
R
-
Y
------
G
N
-
F
H
V
I
R
E
T
T
M
P
A
V
L
L
E
V
G
Y
L
S
N
A
K
E
E
A
T
L
F
D
E
D
F
Q
N
R
V
A
Q
G
I
A
D
G
I
T
E
Y
--------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
64.65
37%
54
- C4 -
4RN7
6
?
A:
[2-183]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
A
Y
T
V
F
I
D
P
G
H
---
G
G
N
D
K
G
T
E
S
KT-------------------
S
--
N
-
R
Y
E
K
D
L
N
L
Q
I
A
K
K
L
A
N
K
L
S
-
K
Q
K
-
D
---
I
Q
V
--
V
-
V
-
S
R
T
D
D
T
---
Y
I
--
S
L
K
D
R
A
I
L
A
N
N
S
S
A
D
V
L
V
S
I
H
L
N
A
E
-
K
N
G
N
T
A
-
T
G
I
--------------------------------
E
T
-
W
Y
R
N
----
K
-------
A
----
T
----------------------------
D
G
----------------------------------
S
K
E
L
A
----
Q
T
V
Q
--------
S
T
--
I
V
S
-
Y
-----
V
-
K
V
-
R
-----
D
R
G
I
-------------------------
V
-
E
------
N
N
-
F
E
V
L
R
E
S
N
M
P
A
I
L
I
E
C
G
F
L
T
T
P
S
E
E
Q
K
I
I
N
E
K
Y
Q
D
Q
L
A
E
G
I
V
Q
G
V
L
S
Y
L
D
------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
63.30
39%
28
- C4 -
1JWQ
1
?
A:
[2-177]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
V
V
I
D
A
G
H
---
G
A
K
D
S
G
A
V
G
---------------------
I
SR
K
-
N
Y
E
K
T
F
N
L
A
M
A
L
K
V
E
S
I
L
K
-
Q
N
P
-
K
---
L
E
V
--
V
-
L
-
T
R
S
D
D
T
---
F
L
--
E
L
K
Q
R
V
K
V
A
E
N
L
K
A
N
V
F
V
S
I
H
A
N
S
S
-
G
S
-
S
A
S
-
N
G
T
--------------------------------
E
T
-
Y
Y
Q
R
----------------------------------------------
S
A
----------------------------------
S
K
A
F
A
----
N
V
M
H
--------
K
Y
--
F
A
P
-
A
-----
T
-
G
L
-
T
-----
D
R
G
I
-------------------------
R
-
Y
------
G
N
-
F
H
V
I
R
E
T
T
M
P
A
V
L
L
E
V
G
Y
L
S
N
A
K
E
E
A
T
L
F
D
E
D
F
Q
N
R
V
A
Q
G
I
A
D
G
I
T
E
Y
L
D
------------------------------------------------------------------------------------------------------------------------------------------
40
Fugue
63.21
39%
29
* C4 *
1JWQ
1
?
A:
[1-179]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
V
V
V
I
D
A
G
H
---
G
A
K
D
S
G
A
V
G
IS-------------------
R
--
K
-
N
Y
E
K
T
F
N
L
A
M
A
L
K
V
E
S
I
L
K
-
Q
-
N
-
P
---
K
L
E
--
V
-
V
L
T
R
S
D
D
T
---
F
L
--
E
L
K
Q
R
V
K
V
A
E
N
L
K
A
N
V
F
V
S
I
H
A
N
S
S
-
G
S
-
S
A
S
-
N
G
T
--------------------------------
E
T
-
Y
Y
--------------
Q
----
R
----------------------------
S
A
----------------------------------
S
K
A
F
A
----
N
V
M
H
--------
K
Y
--
F
A
P
-
A
-----
T
-
G
L
-
T
-----
D
R
G
I
-------------------------
R
-
Y
------
G
N
-
F
H
V
I
R
E
T
T
M
P
A
V
L
L
E
V
G
Y
L
S
N
A
K
E
E
A
T
L
F
D
E
D
F
Q
N
R
V
A
Q
G
I
A
D
G
I
T
E
Y
L
D
VK----------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
62.44
36%
58
- C4 -
4RN7
6
?
A:
[5-181]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
V
F
I
D
P
G
H
---
G
G
N
D
K
G
T
E
S
KT-------------------
S
--
N
-
R
Y
E
K
D
L
N
L
Q
I
A
K
K
L
A
N
K
L
S
-
K
-
Q
-
K
---
D
I
Q
--
V
-
V
V
S
R
T
D
D
T
---
Y
I
--
S
L
K
D
R
A
I
L
A
N
N
S
S
A
D
V
L
V
S
I
H
L
N
A
E
K
N
G
-
N
T
A
-
T
G
I
--------------------------------
E
T
-
W
Y
-
R
----
N
K
------
A
----
T
----------------------------
D
G
----------------------------------
S
K
E
L
A
----
Q
T
V
Q
--------
S
T
--
I
V
S
-
Y
-----
V
-
K
V
-
R
-----
D
R
G
I
-------------------------
V
-
E
------
N
N
-
F
E
V
L
R
E
S
N
M
P
A
I
L
I
E
C
G
F
L
T
T
P
S
E
E
Q
K
I
I
N
E
K
Y
Q
D
Q
L
A
E
G
I
V
Q
G
V
L
S
Y
--------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
61.40
30%
47
- C4 -
3NE8
8
?
A:
[7-216]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
V
L
D
P
G
H
---
G
G
I
D
G
G
A
R
G
V--------------------
T
--
G
-
I
L
E
K
D
V
T
L
A
F
A
R
A
L
R
D
E
L
Q
K
G
-
S
-
H
---
T
I
V
--
A
-
L
-
T
R
D
S
D
I
---
F
L
--
R
L
S
E
R
V
K
K
A
Q
E
F
D
A
D
L
F
I
S
I
H
A
D
T
I
-
D
V
-
H
S
L
-
R
G
A
---------------------------------
T
-
V
Y
T
I
----
S
D
------
E
----
A
----------------------------
S
D
A
I
--------------------------------
A
K
S
L
A
----
E
S
E
N
K
VDLLDGL
P
K
ED
I
L
L
-
D
-----
L
-
T
R
-
R
-----
E
T
H
A
F
S
I
N
F
A
N
N
V
V
S
N
L
S
K
S
HINLINNP
H
R
-
Y
------
A
D
-
F
Q
V
L
K
A
P
D
V
P
S
V
L
I
E
I
G
Y
L
S
N
K
E
D
E
K
L
L
N
N
P
Q
W
R
K
Q
M
A
A
S
I
---------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
58.00
28%
40
- C4 -
4LQ6
9
PEPAM_MYCTU
A:
[3-212]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
M
V
V
F
I
D
P
G
H
---
N
G
A
N
D
A
S
I
G
R
Q
V
P
TGRGGTKNCQAS
G
T
S
T
N
S
--
G
-
Y
P
E
H
T
F
T
W
E
T
G
L
R
L
R
A
A
L
N
-
A
-
L
-
G
---
V
R
T
--
A
-
L
-
S
R
G
N
D
N
---
A
L
G
P
C
V
D
E
R
A
N
M
A
N
A
L
R
P
N
A
I
V
S
L
H
A
D
G
G
-
P
--
A
S
G
-
R
G
F
--------------------------------
H
V
-
N
Y
S
A
----
P
P
------
L
NAIQ
A
----------------------------
G
P
----------------------------------
S
V
Q
F
A
----
R
I
M
R
--------
D
Q
--
L
Q
A
-
S
-----
G
-
I
P
-
K
ANYIG
Q
D
G
L
-------------------------
Y
G
R
------
S
D
-
L
A
G
L
N
L
A
Q
Y
P
S
I
L
V
E
L
G
N
M
K
N
P
A
D
S
A
L
M
E
S
A
E
G
R
Q
K
Y
A
N
A
L
V
R
G
V
A
G
F
L
A
------------------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
56.74
21%
13
- C4 -
3CZX
1
?
A:
[3-178]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
I
I
C
L
T
A
G
H
---
S
N
T
D
P
G
A
V
N
---------------------
G
--
S
-
D
R
E
A
D
L
A
Q
D
M
R
N
I
V
A
S
I
L
R
-
N
D
Y
-
G
---
L
T
V
--
K
-
T
-
D
G
T
G
K
G
---
N
M
--
P
L
R
D
A
V
K
L
I
R
--
G
S
D
V
A
I
E
F
H
T
N
A
A
-
A
N
-
K
T
A
-
T
G
I
--------------------------------
E
A
-
L
S
T
P
-----------------------------------------------
K
----------------------------------
N
K
R
W
C
----
Q
V
L
G
--------
K
A
--
V
A
K
-
K
-----
T
-
G
W
-
K
-----
L
R
G
E
-------------------------
D
-
G
FKPDNA
G
Q
-
H
S
R
L
A
Y
A
Q
A
G
G
I
V
F
E
P
F
F
I
S
N
D
T
D
L
A
L
F
K
T
T
K
--
W
G
I
C
R
A
I
A
D
A
I
A
M
E
L
G
------------------------------------------------------------------------------------------------------------------------------------------
43
Fugue
54.24
26%
53
- C4 -
4M6G
3
PEPAM_MYCTU
A:
[8-221]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
A
G
M
V
V
F
I
D
P
G
H
NGA
N
D
A
S
I
G
R
Q
V
PTGRGGTKNCQAS
G
T
S
T
N---
S
--
G
-
Y
P
E
H
T
F
T
W
E
T
G
L
R
L
R
A
A
L
N
-
A
-
L
-
G
---
V
R
T
--
A
-
L
-
S
R
G
N
D
N
---
A
L
G
P
C
V
D
E
R
A
N
M
A
N
A
L
R
P
N
A
I
V
S
L
H
A
D
G
G
-
P
A
-
S
G
R
-
G
F
H
--------------------------------
V
N
-
Y
S
A
P
----
P
L
------
N
----
A
----------------------------
I
Q
AG
P
-------------------------------
S
V
Q
F
A
----
R
I
M
R
--------
D
Q
--
L
Q
A
-
S
GIPKA
N
-
Y
I
-
G
-----
Q
D
G
L
-------------------------
Y
-
G
R
-----
S
D
-
L
A
G
L
N
L
A
Q
Y
P
S
I
L
V
E
L
G
N
M
K
N
P
A
D
S
A
L
M
E
S
A
E
G
R
Q
K
Y
A
N
A
L
V
R
G
V
A
G
F
L
A
T
Q----------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
53.98
25%
43
- C4 -
4LQ6
9
PEPAM_MYCTU
A:
[3-210]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
M
V
V
F
I
D
P
G
H
---
N
G
A
N
D
A
S
I
G
R
Q
V
P
TGRGGTKNCQAS
G
T
S
T
N
S
--
G
-
Y
P
E
H
T
F
T
W
E
T
G
L
R
L
R
A
A
L
N
-
A
-
L
-
G
---
V
R
T
--
A
-
L
-
S
R
G
N
D
N
---
A
L
G
P
C
V
D
E
R
A
N
M
A
N
A
L
R
P
N
A
I
V
S
L
H
A
D
G
G
-
P
A
-
S
G
--
R
G
F
--------------------------------
H
V
-
N
Y
S
A
PPLN
A
I
------
Q
----
A
----------------------------
G
P
----------------------------------
S
V
Q
F
A
R
I
M
R
D
Q
L
Q
A
S
GI----
P
K
----
A
-
N
-----
Y
-
I
G
-
Q
-----
D
G
L
Y
-------------------------
G
-
R
------
S
D
-
L
A
G
L
N
L
A
Q
Y
P
S
I
L
V
E
L
G
N
M
K
N
P
A
D
S
A
L
M
E
S
A
E
G
R
Q
K
Y
A
N
A
L
V
R
G
V
A
G
F
--------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
53.53
25%
54
- C4 -
3QAY
6
?
A:
[1-178]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
M
K
I
C
I
T
V
G
H
---
S
I
L
K
S
G
A
C
T
---------------------
S
AD
G
V
V
N
E
Y
Q
Y
N
K
S
L
A
P
V
L
A
D
T
F
R
-
K
-
E
-
G
---
H
K
V
D
V
I
-
I
-
C
P
E
K
Q
F
KTK
N
E
--
E
K
S
Y
K
I
P
R
V
N
S
G
G
Y
D
L
L
I
E
L
H
L
N
A
S
-
N
G
--
Q
G
-
K
G
S
--------------------------------
E
V
-
L
Y
Y
S
----
N
------------------------------------------
K
----------------------------------
G
L
E
Y
A
----
T
R
I
C
--------
D
K
--
L
G
T
-
V
--------
F
-
K
-----
N
R
G
A
-------------------------
K
-
L
D
-----
K
R
-
L
Y
I
L
N
S
S
K
P
T
A
V
L
I
E
S
F
F
C
D
N
K
E
D
Y
D
K
A
K
K
-
L
G
H
E
G
I
A
K
L
I
V
E
G
V
L
N
K
N
-------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
53.44
25%
41
- C4 -
4M6G
3
PEPAM_MYCTU
A:
[8-217]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
A
G
M
V
V
F
I
D
P
G
H
---
N
G
A
N
D
A
S
I
G
RQVPTGRGGTKNCQAS
G
T
S
T
N
S
--
G
-
Y
P
E
H
T
F
T
W
E
T
G
L
R
L
R
A
A
L
N
-
A
-
L
-
G
---
V
R
T
--
A
-
L
-
S
R
G
N
D
N
---
A
L
G
P
C
V
D
E
R
A
N
M
A
N
A
L
R
P
N
A
I
V
S
L
H
A
D
G
G
-
P
A
-
S
G
--
R
G
F
--------------------------------
H
V
-
N
Y
S
A
PPLN
A
I
------
Q
----
A
----------------------------
G
P
----------------------------------
S
V
Q
F
A
R
I
M
R
D
Q
L
Q
A
S
GI----
P
K
----
A
-
N
-----
Y
-
I
G
-
Q
-----
D
G
L
Y
-------------------------
G
-
R
------
S
D
-
L
A
G
L
N
L
A
Q
Y
P
S
I
L
V
E
L
G
N
M
K
N
P
A
D
S
A
L
M
E
S
A
E
G
R
Q
K
Y
A
N
A
L
V
R
G
V
A
G
F
--------------------------------------------------------------------------------------------------------------------------------------------
44
Fugue
51.98
25%
-113
- C- -
4CU2
-
?
A:
[195-274]
--------------------------------------------------
P
E
N
L
V
V
Y
N
D
G
A
--
D
Q
R
A
A
E
Y
L
A
D
R
L
A
C
P
T
I
N
N
A
R
K
F
---------
D
Y
S
N
V
K
N
V
Y
A
V
G
G
N
K
E
Q
Y
T
S
Y
L
T
---------
T
L
I
A
G
S
T
R
Y
T
T
M
Q
A
V
L
D
Y
I
K
N
L
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
49.39
25%
55
- C4 -
4M6I
1
PEPAM_MYCTU
A:
[8-217]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
A
G
M
V
V
F
I
D
P
G
H
------------TSTN-----------------
S
--
G
-
Y
P
E
H
T
F
T
W
E
T
G
L
R
L
R
A
A
L
N
-
A
-
L
-
G
---
V
R
T
--
A
-
L
-
S
R
G
N
D
------GP
C
V
D
E
R
A
N
M
A
N
A
L
R
P
N
A
I
V
S
L
H
A
D
G
G
-
P
A
-
S
G
--
R
G
F
--------------------------------
H
V
-
N
Y
S
A
PPLN
A
I
------
Q
----
A
----------------------------
G
P
----------------------------------
S
V
Q
F
A
R
I
M
R
D
Q
L
Q
A
S
GI----
P
K
----
A
-
N
-----
Y
-
I
G
-
Q
-----
D
G
L
Y
-------------------------
G
-
R
------
S
D
-
L
A
G
L
N
L
A
Q
Y
P
S
I
L
V
E
L
G
N
M
K
N
P
A
D
S
A
L
M
E
S
A
E
G
R
Q
K
Y
A
N
A
L
V
R
G
V
A
G
F
--------------------------------------------------------------------------------------------------------------------------------------------