@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu35730: (2016-07-30 )
MSLHAVSESNIKQIPDMDYYFISGGLPSNYGGLTKSLLLRSKLFGEECNQNTFFLTFRFDLELSSKIDELYSNGKIDKKFTSVINLFDDFLSVRTNGKRSYEERIGLDQIKKQVGMGKFAKTLLRLFGKKNNEMSVVYYGDGETIRYVDYWNDKNQLIKREEYTKNGNLVLVTHYDVQLNKMYLQEYINDQNQVYLDKLYVWNNEEKDVQLSHIIWYSLEGEIKVKDESELRQYWIEYLQKQNDKPKLFLVDSRPQDKHVFKVKKSPSSYYGAIIHNKHYGSNKYQIKGRYKEVFSQMYNLDAVFFITEEQLEDFKLISGEQETFFFTPHTIDKPLDPAVLNVPSEKYKAVIISRLASMKNLIHAVKAFSLVVKEIPEAKLDIFGSGEDFEKIKKEIEDTKLQNNVFLKGYTDNPDSEFQKAWLTISTSHFEGFGLSNMEALSNGCPVVTYDYDYGARSLVTDGANGYVIEQYNIEKLGQAIISLMKDESTHQKFSEQAFKMAEKYSRPNYIENWAFALNQMIEVRIEREKFSKKVGKKDPSISSYTEDFDKTKIEIDIENFDHNDIKKIRLVGLDRKNKAEIISTNLQNDQLFVIDLEKDVNIEKIAANKTQVIDFYIVFNANGHIKTMRRLSSEETKLSGNSIDTNNGYRVEPYTTVKGNFSWRVTEIKES
Atome Classification :
(20 SA)
.........10........20........30........40........50........--60-.........70..-......80........90.......--------.100...-....-110--...---......----120-----......-.-130...-....140.--........150.......160-........170.......180.........190..-----.....200.......210..-.....220........230.........240.-......250.....-.--.-260.-.--.-.....270.......-280...----.-----.--.-----------------.-----.290----....-.....300..-...--.-.310----.----......---------------------320-------.----........-330.......340------------.-----------------------------.-----------------------------......350---.......360.......370.......380.......-----390---------.........400.......410--.----..--......-420.......430-----.........440.......450.......460..---------.....-------470-----...-------.-------....480.....----..490.......500........510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MSLHAVSES
N
I
KQIPDM
D
Y
Y
F
ISGGLPSNY
G
G
L
T
K
S
L
L
L
R
S
K
LFGEECNQ
N
T
F
F
L
T
F
R
F
--D--L
E
L
S
S
K
I
D
E
L
Y
SN-GKI
D
K
K
F
T
S
V
I
N
L
F
D
D
F
L
S
V
RTNGK--------
R
S
Y
E
E
RI-
G
L
D
Q
-
I
----
K
K
Q
---VGM
G
K
F
----
A
K
T
-----
L
L
R
L
FG-K-KNN
E
M
S
-
V
V
Y
YG--D--G
E
T
I
R
Y
V
DYWN
D
K
N
Q
L
I
K
R
E
--EYTKNG
N
L
V
L
V
T
HYDV
Q
L
N
--
K
M
Y
L
Q
E
Y
INDQ
N
Q
V
-----
Y
L
D
K
L
Y
V
WNNEEKD
V
Q
L
S
H
I
-
I
W
Y
SLE
G
-
E
I
K
VK
D
E
S
E
--
L
R
Q
Y
W
I
E
Y
L
Q
KQN-DKP
K
L
F
L
VDSRPQD-
K
--
H
-
V
-
F
K
-V--K-KSPSS
Y
Y
G
A
I
I
H
NKH-YG-SN
K
----
Y
-----
Q
--
I
-----------------
K
-----
G
R
------
Y
K
E
V
-
F
S
Q
M
YNL
D
A
V
-
F
F
I
--
T
-
E
E
Q
L
----
E
----
D
FKLIS---------------------G---------E----Q
E
T
F
F
FTP-HTIDKPLD
P
A
VL-------------N-----------------------------V-----------------------------P
S
E
K
Y
K
A
V
I
---
I
S
R
L
A
S
M
K
N
L
I
H
A
V
K
A
F
S
L
V
V
K
EIPEA
K
L
D
I
FGSG
E
D
-----
F
-----------
E
K
I
K
K
E
I
E
D
TKLQN
N
V
F
L
K
G----Y----TD--NP
D
S
E
F
-
Q
K
A
W
L
T
I
STSH-------FEGFGL
S
N
M
E
A
LSNGC
P
V
V
T
Y
DYDYGA
R
S
L
VTDG---------AN
G
Y
V
-------
I
E
------QY
N
-------
I
-------
E
K
L
G
Q
A
I
I
S
L
MK----DE
S
T
H
Q
K
F
S
E
Q
A
F
K
-
M
A
E
K
YSRP
N
Y
I
E
N
W
A
F
A
L
N
Q
M
I
E
V
R
I
E
R
E
K
F
S
K
K
VGKKDPSI
S
S
Y
T
EDFDK
T
K
I
E
I
D
IENFDHND
I
K
K
I
R
L
V
GLDRKNK
A
E
I
I
S
TNLQN
D
Q
L
F
V
I
DLEKDV
N
I
E
KIAANK
T
Q
V
I
D
F
Y
I
V
F
NANG
H
I
K
T
M
R
R
LSSEETKLSGNSIDTNN
G
Y
R
V
E
P
Y
T
T
V
KGN
F
S
W
R
V
T
E
IKES
41
Fugue
79.11
27%
22
- C1 -
4X7P
8
?
A:
[1-493]
---------------
M
K
K
I
F
M
M
V
H
E
L
D
V
N
K
G
G
M
T
S
S
M
F
N
R
S
K
E
F
Y
D
A
-
D
I
P
A
D
I
V
T
F
D
Y
--
K
--
G
N
Y
D
E
I
I
K
A
L
K
K
Q
-
G
K
M
D
R
R
-
T
K
M
Y
N
V
F
E
Y
F
K
Q
I
-
S
N
N
K
--------
H
F
K
S
N
K
L
-
L
Y
K
H
-
I
----
S
E
R
L
KN
T
I
E
I
E
E
----
S
K
G
-----
I
S
R
Y
F
D
-
I
-
T
T
G
T
-
Y
-
I
A
Y
I
R
--
K
--
S
K
S
E
K
V
I
D
F
F
K
D
-
N
K
R
I
E
R
F
--
S
F
I
D
N
-
K
V
H
M
K
E
T
F
N
V
D
-
N
--
K
V
C
Y
Q
V
F
Y
D
E
K
G
Y
P
-----
Y
I
S
R
N
I
--
N
A
N
N
G
A
V
G
K
T
Y
V
-----
L
V
N
-
K
K
E
F
K
N
N
L
A
--
L
C
V
Y
Y
L
E
K
L
I
K
-
D
-
S
K
D
S
I
M
I
C
D
G
P
G
S
F
-
P
--
K
-
M
-
F
N
-
T
--
N
-
H
K
N
A
Q
K
Y
G
V
I
H
V
N
H
H
E
N
F
-
D
D
T
----
G
-----
A
--
F
-----------------
K
-----
K
S
------
E
K
Y
I
-
I
E
N
A
N
K
I
N
G
V
-
I
V
L
--
T
-
E
A
Q
R
----
L
----
D
I
L
N
Q
F
-------------------------------
D
----
V
E
N
I
F
T
I
S
-
N
F
V
K
I
H
N
A
P
K
---------------
H
-----------------------------
F
-----------------------------
Q
T
E
K
-
I
V
G
H
---
I
S
R
M
V
P
T
K
R
I
D
L
L
I
E
V
A
E
L
V
V
K
K
D
N
A
V
K
F
H
I
Y
G
E
G
S
V
-----
K
-----------
D
K
I
A
K
M
I
E
D
K
N
L
E
R
N
V
F
L
K
G
----
Y
----
T
T
--
T
P
Q
K
C
L
-
E
D
F
K
L
V
V
S
T
S
Q
-------
Y
E
G
Q
G
L
S
M
I
E
A
M
I
S
K
R
P
V
V
A
F
D
I
K
Y
G
P
S
D
F
I
E
D
N
---------
K
N
G
Y
L
-------
I
E
------
N
H
N
-------
I
-------
N
D
M
A
D
K
I
L
Q
L
V
N
----
N
D
V
L
A
A
E
F
G
S
K
A
R
E
N
I
I
E
K
Y
S
T
E
S
I
L
E
K
W
L
N
L
F
N
S
--------------------------------------------------------------------------------------------------------------------------------------------------------
42
Fugue
72.77
22%
4
- C1 -
4PQG
2
?
A:
[6-511]
-------------
H
H
H
M
T
I
Y
N
I
N
L
G
I
G
W
A
S
S
G
V
E
Y
A
Q
A
Y
R
A
G
V
F
R
K
L
N
L
S
S
K
F
I
F
T
-----
D
--
M
I
L
A
D
N
I
Q
H
L
T
A
N
-
I
G
F
D
D
N
Q
--
V
I
W
L
Y
N
H
F
T
D
I
K
I
A
P
T
--------
S
-----
V
-
T
V
D
D
-
V
----
L
A
Y
---
F
G
G
E
----------------
E
S
H
R
-
E
-
K
N
G
K
V
L
-
R
V
F
F
F
--
D
--
Q
D
K
F
V
T
C
Y
L
V
D
E
N
K
D
L
V
Q
H
A
--
E
Y
V
F
K
G
N
L
I
R
K
D
Y
F
S
Y
T
-----
R
Y
C
S
E
Y
F
A
P
K
D
N
V
-----
A
V
L
Y
Q
R
T
F
Y
N
E
D
G
T
P
V
Y
D
I
L
-
M
N
Q
G
K
E
E
-
V
Y
H
F
K
D
K
I
F
Y
G
K
Q
A
F
V
R
A
F
M
K
S
L
N
L
N
K
S
D
L
V
I
L
D
R
E
T
G
I
-
G
--
Q
-
V
-
V
--
F
--
E
-
E
A
Q
T
A
H
L
A
V
V
V
H
A
E
H
-
Y
S
-
E
N
A
----
T
-----
N
--
E
-----------------
D
Y
I
L
W
N
N
Y
------
Y
D
Y
Q
-
F
T
N
A
D
K
V
D
F
F
-
I
V
S
--
T
-
D
R
Q
N
----
E
V
L
Q
E
Q
F
A
K
Y
T
---------------------
Q
---------
H
----
Q
P
K
I
V
T
I
P
-
V
G
S
I
D
S
L
T
D
S
---------------
S
-----------------------------
Q
-----------------------------
G
R
K
P
F
S
L
I
T
---
A
S
R
L
A
K
E
K
H
I
D
W
L
V
K
A
V
I
E
A
H
K
E
L
P
E
L
T
F
D
I
Y
G
S
G
G
E
-----
D
-----------
S
L
L
R
E
I
I
A
N
H
Q
A
E
D
Y
I
Q
L
K
G
----
H
----
A
E
---
L
S
Q
I
Y
-
S
Q
Y
E
V
Y
L
T
A
S
T
-------
S
E
G
F
G
L
T
L
M
E
A
I
G
S
G
L
P
L
I
G
F
D
V
P
Y
G
N
Q
T
F
I
E
D
G
---------
Q
N
G
Y
L
-------
I
P
SSSDHV
E
D
Q
-------
I
-------
K
Q
A
Y
A
A
K
I
C
Q
L
Y
----
Q
E
N
R
L
E
A
M
R
A
Y
S
Y
Q
-
I
A
E
G
F
L
T
K
E
I
L
E
K
W
K
K
T
V
E
E
V
L
H
D
----------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
72.16
24%
42
- C1 -
4X7R
3
?
A:
[2-492]
----------------
K
K
I
F
M
M
V
H
E
L
D
V
N
K
G
G
M
T
S
S
M
F
N
R
S
K
E
F
Y
D
A
-
D
I
P
A
D
I
V
T
F
D
Y
--
K
--
G
N
Y
D
E
I
I
K
A
L
K
K
Q
-
G
K
M
D
R
R
T
-
K
M
Y
N
V
F
E
Y
F
K
Q
I
S
N
N
K
H
--------
F
K
S
N
K
L
L
-
Y
K
H
I
-
S
E
R
--
L
K
N
---
T
I
--
E
I
E
---
E
S
K
-----
G
I
S
R
Y
F
-
D
I
T
T
R
T
Y
I
-
A
Y
I
R
K
-----
S
K
S
E
K
V
I
D
F
F
K
D
-
N
K
R
I
E
R
F
--
S
F
-
I
D
N
K
V
H
M
K
E
T
F
N
V
D
N
K
---
V
C
Y
Q
V
F
Y
D
E
K
G
Y
P
-----
Y
I
S
R
N
I
N
A
N
N
G
A
---
V
G
K
T
Y
-
V
L
V
---
N
-
K
K
E
F
K
N
N
L
A
--
L
C
V
Y
Y
L
E
K
L
I
-
K
D
-
S
K
D
S
I
M
I
C
D
G
P
G
S
F
-
P
--
K
-
M
-
F
N
-
T
NH
K
N
A
-
Q
K
Y
G
V
I
H
V
N
H
H
E
N
-
F
D
-
D
T
G
----------
A
--
F
-----------------
K
-----
K
S
------
E
K
Y
I
-
I
E
N
A
N
K
I
N
G
V
-
I
V
L
--
T
-
E
A
Q
R
----
L
----
D
I
L
N
Q
F
---------------------
D
--------------
V
E
N
I
F
T
I
S
-
N
F
V
K
I
H
N
A
P
----------------
K
-----------------------------
H
-----------------------------
F
Q
T
E
K
I
V
G
H
---
I
S
R
M
V
P
T
K
R
I
D
L
L
I
E
V
A
E
L
V
V
K
K
D
N
A
V
K
F
H
I
Y
G
E
G
S
V
-----
K
-----------
D
K
I
A
K
M
I
E
D
K
N
L
E
R
N
V
F
L
K
G
----
Y
----
T
T
--
T
P
Q
K
C
L
-
E
D
F
K
L
V
V
S
T
S
Q
-------
Y
E
G
Q
G
L
S
M
I
E
A
M
I
S
K
R
P
V
V
A
F
D
I
K
Y
G
P
S
D
F
I
E
D
N
---------
K
N
G
Y
L
-------
I
E
------
N
H
N
-------
I
-------
N
D
M
A
D
K
I
L
Q
L
V
N
----
N
D
V
L
A
A
E
F
G
S
K
A
R
E
N
I
I
E
K
Y
S
T
E
S
I
L
E
K
W
L
N
L
F
N
---------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
71.16
26%
39
- C1 -
4X7P
8
?
A:
[11-487]
-------------------------
L
D
V
N
K
G
G
M
T
S
S
M
F
N
R
S
K
E
F
-
Y
D
A
D
I
P
A
D
I
V
T
F
D
Y
--
K
--
G
N
Y
D
E
I
I
K
A
L
K
K
Q
-
G
K
M
D
R
R
-
T
K
M
Y
N
V
F
E
Y
F
K
Q
I
S
N
N
K
H
FKSN
K
L
L
Y
K
H
I
S
E
R
L
K
N
T
I
E
-
I
----
E
E
S
---
K
G
I
S
R
Y
F
D
IT
T
G
T
-----
Y
I
A
Y
I
R
-
K
-
S
K
S
E
K
V
-
I
D
F
F
K
--
D
--
N
K
R
I
E
R
F
S
F
I
D
N
K
V
H
M
--
K
E
--
T
F
N
V
D
N
K
V
C
Y
Q
V
F
Y
D
-
E
K
G
--
Y
P
Y
I
S
R
N
I
N
A
N
N
G
A
------
V
G
K
T
Y
V
L
V
N
K
K
E
-------------------
F
K
N
N
L
A
--
L
C
V
Y
Y
L
E
K
L
I
K
-
D
-
S
K
D
S
I
M
I
C
D
G
P
G
S
F
-
P
--
K
-
M
-
F
N
-
T
--
N
-
H
K
N
A
Q
K
Y
G
V
I
H
V
N
H
H
-
E
N
F
D
D
T
----
G
-----
A
--
F
-----------------
K
-----
K
S
------
E
K
Y
I
-
I
E
N
A
N
K
I
N
G
V
-
I
V
L
--
T
-
E
A
Q
R
----
L
----
D
I
-
L
N
Q
---------------------
F
---------
D
----
V
E
N
I
F
T
I
S
-
N
F
V
------
K
I
H
-------------
N
-----------------------------
A
-----------------------------
P
K
H
F
Q
T
E
K
I
V
G
H
I
S
R
M
V
P
T
K
R
I
D
L
L
I
E
V
A
E
L
V
V
K
K
D
N
A
V
K
F
H
I
Y
G
E
G
S
V
-----
K
-----------
D
K
I
A
K
M
I
E
D
K
N
L
E
R
N
V
F
L
K
G
----
Y
----
T
T
--
T
P
Q
K
C
L
-
E
D
F
K
L
V
V
S
T
S
Q
-------
Y
E
G
Q
G
L
S
M
I
E
A
M
I
S
K
R
P
V
V
A
F
D
I
K
Y
G
P
S
D
F
I
E
D
N
---------
K
N
G
Y
L
-------
I
E
------
N
H
N
-------
I
-------
N
D
M
A
D
K
I
L
Q
L
V
N
----
N
D
V
L
A
A
E
F
G
S
K
A
R
E
N
I
I
E
K
Y
S
T
E
S
I
L
E
K
W
--------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
70.43
26%
41
- C1 -
4X7M
1
?
A:
[11-487]
-------------------------
L
D
V
N
K
G
G
M
T
S
S
M
F
N
R
S
K
E
F
-
Y
D
A
D
I
P
A
D
I
V
T
F
D
Y
--
K
--
G
N
Y
D
E
I
I
K
A
L
K
K
Q
-
G
K
M
D
R
R
-
T
K
M
Y
N
V
F
E
Y
F
K
Q
I
S
N
N
K
H
FKSN
K
L
L
Y
K
H
I
S
E
R
L
K
N
T
I
E
-
I
----
E
E
S
---
K
G
I
S
R
Y
----
F
D
I
-----
T
T
R
T
Y
-----------
I
A
Y
I
R
--
K
--
S
K
S
E
K
V
I
D
F
F
K
D
-
N
K
R
I
E
R
F
--
S
F
I
D
N
----------------
K
V
H
M
K
E
T
F
N
V
D
N
K
V
C
Y
Q
V
F
Y
D
E
K
G
Y
P
Y
I
S
R
N
I
N
A
N
N
G
A
V
G
K
T
Y
V
L
V
N
-
K
K
E
F
K
N
N
L
A
--
L
C
V
Y
Y
L
E
K
L
I
K
-
D
-
S
K
D
S
I
M
I
C
D
G
P
G
S
F
-
P
--
K
-
M
-
F
N
-
T
--
N
-
H
K
N
A
Q
K
Y
G
V
I
H
V
N
H
H
-
E
N
F
D
D
T
----
G
-----
A
--
F
-----------------
K
-----
K
S
------
E
K
Y
I
-
I
E
N
A
N
K
I
N
G
V
-
I
V
L
--
T
-
E
A
Q
R
----
L
----
D
I
-
L
N
Q
---------------------
F
---------
D
----
V
E
N
I
F
T
I
S
-
N
F
V
------
K
I
H
-------------
N
-----------------------------
A
-----------------------------
P
K
H
F
Q
T
E
K
I
V
G
H
I
S
R
M
V
P
T
K
R
I
D
L
L
I
E
V
A
E
L
V
V
K
K
D
N
A
V
K
F
H
I
Y
G
E
G
S
V
-----
K
-----------
D
K
I
A
K
M
I
E
D
K
N
L
E
R
N
V
F
L
K
G
----
Y
----
T
T
--
T
P
Q
K
C
L
-
E
D
F
K
L
V
V
S
T
S
Q
-------
Y
E
G
Q
G
L
S
M
I
E
A
M
I
S
K
R
P
V
V
A
F
D
I
K
Y
G
P
S
D
F
I
E
D
N
---------
K
N
G
Y
L
-------
I
E
------
N
H
N
-------
I
-------
N
D
M
A
D
K
I
L
Q
L
V
N
----
N
D
V
L
A
A
E
F
G
S
K
A
R
E
N
I
I
E
K
Y
S
T
E
S
I
L
E
K
W
--------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
70.23
26%
39
- C1 -
4WAD
5
?
A:
[16-492]
-------------------------
L
D
V
N
K
G
G
M
T
S
S
M
F
N
R
S
K
E
F
-
Y
D
A
D
I
P
A
D
I
V
T
F
D
Y
--
K
--
G
N
Y
D
E
I
I
K
A
L
K
K
Q
-
G
K
M
D
R
R
-
T
K
M
Y
N
V
F
E
Y
F
K
Q
I
S
N
N
K
H
FKSN
K
L
L
Y
K
H
I
S
E
R
L
K
N
T
I
E
-
I
----
E
E
S
---
K
G
I
S
R
Y
F
D
IT
T
G
T
-----
Y
I
A
Y
I
R
-
K
-
S
K
S
E
K
V
-
I
D
F
F
K
--
D
--
N
K
R
I
E
R
F
S
F
I
D
N
K
V
H
M
--
K
E
--
T
F
N
V
D
N
K
V
C
Y
Q
V
F
Y
D
-
E
K
G
--
Y
P
Y
I
S
R
N
I
N
A
N
N
G
A
------
V
G
K
T
Y
V
L
V
N
K
K
E
-------------------
F
K
N
N
L
A
--
L
C
V
Y
Y
L
E
K
L
I
K
-
D
-
S
K
D
S
I
M
I
C
D
G
P
G
S
F
-
P
--
K
-
M
-
F
N
-
T
--
N
-
H
K
N
A
Q
K
Y
G
V
I
H
V
N
H
H
-
E
N
F
D
D
T
----
G
-----
A
--
F
-----------------
K
-----
K
S
------
E
K
Y
I
-
I
E
N
A
N
K
I
N
G
V
-
I
V
L
--
T
-
E
A
Q
R
----
L
----
D
I
-
L
N
Q
---------------------
F
---------
D
----
V
E
N
I
F
T
I
S
-
N
F
V
------
K
I
H
-------------
N
-----------------------------
A
-----------------------------
P
K
H
F
Q
T
E
K
I
V
G
H
I
S
R
M
V
P
T
K
R
I
D
L
L
I
E
V
A
E
L
V
V
K
K
D
N
A
V
K
F
H
I
Y
G
E
G
S
V
-----
K
-----------
D
K
I
A
K
M
I
E
D
K
N
L
E
R
N
V
F
L
K
G
----
Y
----
T
T
--
T
P
Q
K
C
L
-
E
D
F
K
L
V
V
S
T
S
Q
-------
Y
E
G
Q
G
L
S
M
I
E
A
M
I
S
K
R
P
V
V
A
F
D
I
K
Y
G
P
S
D
F
I
E
D
N
---------
K
N
G
Y
L
-------
I
E
------
N
H
N
-------
I
-------
N
D
M
A
D
K
I
L
Q
L
V
N
----
N
D
V
L
A
A
E
F
G
S
K
A
R
E
N
I
I
E
K
Y
S
T
E
S
I
L
E
K
W
--------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
70.13
26%
38
- C1 -
4WAC
6
?
A:
[16-492]
-------------------------
L
D
V
N
K
G
G
M
T
S
S
M
F
N
R
S
K
E
F
-
Y
D
A
D
I
P
A
D
I
V
T
F
D
Y
--
K
--
G
N
Y
D
E
I
I
K
A
L
K
K
Q
-
G
K
M
D
R
R
-
T
K
M
Y
N
V
F
E
Y
F
K
Q
I
S
N
N
K
H
FKSN
K
L
L
Y
K
H
I
S
E
R
L
K
N
T
I
E
-
I
----
E
E
S
---
K
G
I
S
R
Y
F
D
IT
T
G
T
-----
Y
I
A
Y
I
R
-
K
-
S
K
S
E
K
V
-
I
D
F
F
K
--
D
--
N
K
R
I
E
R
F
S
F
I
D
N
K
V
H
M
--
K
E
--
T
F
N
V
D
N
K
V
C
Y
Q
V
F
Y
D
-
E
K
G
--
Y
P
Y
I
S
R
N
I
N
A
N
N
G
A
------
V
G
K
T
Y
V
L
V
N
K
K
E
-------------------
F
K
N
N
L
A
--
L
C
V
Y
Y
L
E
K
L
I
K
-
D
-
S
K
D
S
I
M
I
C
D
G
P
G
S
F
-
P
--
K
-
M
-
F
N
-
T
--
N
-
H
K
N
A
Q
K
Y
G
V
I
H
V
N
H
H
-
E
N
F
D
D
T
----
G
-----
A
--
F
-----------------
K
-----
K
S
------
E
K
Y
I
-
I
E
N
A
N
K
I
N
G
V
-
I
V
L
--
T
-
E
A
Q
R
----
L
----
D
I
-
L
N
Q
---------------------
F
---------
D
----
V
E
N
I
F
T
I
S
-
N
F
V
------
K
I
H
-------------
N
-----------------------------
A
-----------------------------
P
K
H
F
Q
T
E
K
I
V
G
H
I
S
R
M
V
P
T
K
R
I
D
L
L
I
E
V
A
E
L
V
V
K
K
D
N
A
V
K
F
H
I
Y
G
E
G
S
V
-----
K
-----------
D
K
I
A
K
M
I
E
D
K
N
L
E
R
N
V
F
L
K
G
----
Y
----
T
T
--
T
P
Q
K
C
L
-
E
D
F
K
L
V
V
S
T
S
Q
-------
Y
E
G
Q
G
L
S
M
I
E
A
M
I
S
K
R
P
V
V
A
F
D
I
K
Y
G
P
S
D
F
I
E
D
N
---------
K
N
G
Y
L
-------
I
E
------
N
H
N
-------
I
-------
N
D
M
A
D
K
I
L
Q
L
V
N
----
N
D
V
L
A
A
E
F
G
S
K
A
R
E
N
I
I
E
K
Y
S
T
E
S
I
L
E
K
W
--------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
69.53
26%
39
- C1 -
4X6L
1
?
A:
[11-487]
-------------------------
L
D
V
N
K
G
G
M
T
S
S
M
F
N
R
S
K
E
F
-
Y
D
A
D
I
P
A
D
I
V
T
F
D
Y
--
K
--
G
N
Y
D
E
I
I
K
A
L
K
K
Q
-
G
K
M
D
R
R
-
T
K
M
Y
N
V
F
E
Y
F
K
Q
I
S
N
N
K
H
FKSN
K
L
L
Y
K
H
I
S
E
R
L
K
N
T
I
E
-
I
----
E
E
S
---
K
G
I
S
R
Y
F
D
IT
T
G
T
-----
Y
I
A
Y
I
R
-
K
-
S
K
S
E
K
V
-
I
D
F
F
K
--
D
--
N
K
R
I
E
R
F
S
F
I
D
N
K
V
H
M
--
K
E
--
T
F
N
V
D
N
K
V
C
Y
Q
V
F
Y
D
-
E
K
G
--
Y
P
Y
I
S
R
N
I
N
A
N
N
G
A
------
V
G
K
T
Y
V
L
V
N
K
K
E
-------------------
F
K
N
N
L
A
--
L
C
V
Y
Y
L
E
K
L
I
K
-
D
-
S
K
D
S
I
M
I
C
D
G
P
G
S
F
-
P
--
K
-
M
-
F
N
-
T
--
N
-
H
K
N
A
Q
K
Y
G
V
I
H
V
N
H
H
-
E
N
F
D
D
T
----
G
-----
A
--
F
-----------------
K
-----
K
S
------
E
K
Y
I
-
I
E
N
A
N
K
I
N
G
V
-
I
V
L
--
T
-
E
A
Q
R
----
L
----
D
I
-
L
N
Q
---------------------
F
---------
D
----
V
E
N
I
F
T
I
S
-
N
F
V
------
K
I
H
-------------
N
-----------------------------
A
-----------------------------
P
K
H
F
Q
T
E
K
I
V
G
H
I
S
R
M
V
P
T
K
R
I
D
L
L
I
E
V
A
E
L
V
V
K
K
D
N
A
V
K
F
H
I
Y
G
E
G
S
V
-----
K
-----------
D
K
I
A
K
M
I
E
D
K
N
L
E
R
N
V
F
L
K
G
----
Y
----
T
T
--
T
P
Q
K
C
L
-
E
D
F
K
L
V
V
S
T
S
Q
-------
Y
E
G
Q
G
L
S
M
I
E
A
M
I
S
K
R
P
V
V
A
F
D
I
K
Y
G
P
S
D
F
I
E
D
N
---------
K
N
G
Y
L
-------
I
E
------
N
H
N
-------
I
-------
N
D
M
A
D
K
I
L
Q
L
V
N
----
N
D
V
L
A
A
E
F
G
S
K
A
R
E
N
I
I
E
K
Y
S
T
E
S
I
L
E
K
W
--------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
69.42
26%
45
- C1 -
4X7R
3
?
A:
[11-487]
-------------------------
L
D
V
N
K
G
G
M
T
S
S
M
F
N
R
S
K
E
F
-
Y
D
A
D
I
P
A
D
I
V
T
F
D
Y
--
K
--
G
N
Y
D
E
I
I
K
A
L
K
K
Q
-
G
K
M
D
R
R
-
T
K
M
Y
N
V
F
E
Y
F
K
Q
I
S
N
N
K
H
FKSN
K
L
L
Y
K
H
I
S
E
R
L
K
N
T
I
E
-
I
----
E
E
S
---
K
G
I
S
R
Y
----
F
D
I
-----
T
T
R
T
Y
-----------
I
A
Y
I
R
--
K
--
S
K
S
E
K
V
I
D
F
F
K
D
-
N
K
R
I
E
R
F
--
S
F
I
D
N
----------------
K
V
H
M
K
E
T
F
N
V
D
N
K
V
C
Y
Q
V
F
Y
D
E
K
G
Y
P
Y
I
S
R
N
I
N
A
N
N
G
A
V
G
K
T
Y
V
L
V
N
-
K
K
E
F
K
N
N
L
A
--
L
C
V
Y
Y
L
E
K
L
I
K
-
D
-
S
K
D
S
I
M
I
C
D
G
P
G
S
F
-
P
--
K
-
M
-
F
N
-
T
--
N
-
H
K
N
A
Q
K
Y
G
V
I
H
V
N
H
H
-
E
N
F
D
D
T
----
G
-----
A
--
F
-----------------
K
-----
K
S
------
E
K
Y
I
-
I
E
N
A
N
K
I
N
G
V
-
I
V
L
--
T
-
E
A
Q
R
----
L
----
D
I
-
L
N
Q
---------------------
F
---------
D
----
V
E
N
I
F
T
I
S
-
N
F
V
------
K
I
H
-------------
N
-----------------------------
A
-----------------------------
P
K
H
F
Q
T
E
K
I
V
G
H
I
S
R
M
V
P
T
K
R
I
D
L
L
I
E
V
A
E
L
V
V
K
K
D
N
A
V
K
F
H
I
Y
G
E
G
S
V
-----
K
-----------
D
K
I
A
K
M
I
E
D
K
N
L
E
R
N
V
F
L
K
G
----
Y
----
T
T
--
T
P
Q
K
C
L
-
E
D
F
K
L
V
V
S
T
S
Q
-------
Y
E
G
Q
G
L
S
M
I
E
A
M
I
S
K
R
P
V
V
A
F
D
I
K
Y
G
P
S
D
F
I
E
D
N
---------
K
N
G
Y
L
-------
I
E
------
N
H
N
-------
I
-------
N
D
M
A
D
K
I
L
Q
L
V
N
----
N
D
V
L
A
A
E
F
G
S
K
A
R
E
N
I
I
E
K
Y
S
T
E
S
I
L
E
K
W
--------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
60.94
19%
19
* C1 *
5E9T
1
?
A:
[1-502]
----------------
S
T
V
Y
N
I
N
L
G
I
G
W
A
S
S
G
V
E
Y
A
Q
A
Y
R
A
Q
I
L
R
R
I
-
Q
Q
P
A
K
F
I
F
M
D
M
--
I
LA
D
N
I
Q
H
L
T
E
N
I
G
------
F
L
D
E
-
E
I
I
W
L
Y
N
Y
F
T
D
I
K
I
A
P
T
--------
T
V
T
L
D
Q
V
-
L
A
Q
V
A
G
----
Q
P
E
---
R
S
--
E
-----
K
E
G
-----
K
I
V
R
Y
F
Y
P
-
Q
D
D
Q
F
I
T
C
Y
L
R
Q
--
E
D-
Q
D
F
V
E
H
V
E
Y
V
S
R
-
G
R
L
I
R
K
D
--
Y
F
S
Y
V
R
Y
--
A
S
E
Y
F
A
P
H
N
D
AA
T
L
Y
Q
R
R
F
Y
H
E
D
G
S
V
-----
A
Y
D
M
L
I
E
D
G
---------
Q
E
-
K
L
Y
-
R
F
P
-
D
R
I
F
Y
S
K
A
E
--
L
V
R
Y
F
L
Q
C
L
Q
-
L
Q
--
A
D
D
V
V
I
L
D
R
E
T
G
I
-
G
--
Q
-
V
-
V
F
-
E
--
E
-
S
-
Q
K
A
K
L
G
V
V
V
H
A
E
H
-
F
S
-
E
N
A
----
S
SDD
Y
I
L
--
W
-----------------
N
-----
N
F
------
Y
D
Y
Q
-
F
T
N
A
D
K
V
D
F
F
-
I
V
A
--
T
-
E
A
Q
K
----
R
----
I
L
E
Q
Q
F
---------------------
Q
---------
H
YSDK
Q
P
Q
I
A
T
I
P
-
V
G
S
L
D
Q
L
T
Y
P
---------------
K
-----------------------------
E
-----------------------------
P
R
K
P
Y
S
M
I
T
---
A
S
R
L
A
T
E
K
H
I
D
W
L
V
A
A
T
V
Q
A
H
A
Q
L
P
E
L
T
L
D
I
Y
G
K
G
S
E
-----
E
-----------
D
K
L
R
R
R
I
E
E
A
G
A
Q
D
Y
I
R
L
K
G
----
H
-----
A
--
D
L
S
Q
I
Y
-
A
G
Y
E
L
Y
L
T
A
S
T
-------
S
E
G
F
G
L
T
L
M
E
A
V
G
S
G
L
P
L
I
G
F
D
V
R
Y
G
N
Q
T
F
I
D
D
G
---------
K
N
G
Y
L
-------
L
P
------
V
S
S
N
H
V
E
D
Q
I
I
-------
A
A
F
V
E
K
I
I
A
L
F
S
----
Q
G
-
R
Q
Q
E
M
S
Q
H
S
Y
Q
-
V
A
E
N
Y
L
T
S
R
V
E
A
A
W
T
Q
L
L
K
E
V
R
D
-----------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
58.11
18%
25
- C1 -
4PQG
2
?
A:
[7-510]
--------------
H
H
M
T
I
Y
N
I
N
L
G
I
G
W
A
S
S
G
V
E
Y
A
Q
A
Y
R
A
G
V
F
R
K
L
-
N
L
S
S
K
F
I
F
T
D
M
IL
A
--
D
N
I
Q
H
L
T
A
N
I
G
------
F
D
D
N
-
Q
V
I
W
L
Y
N
H
F
T
D
I
K
I
A
P
T
--------
S
V
----
T
-
V
D
D
V
-
L
A
Y
F
G
G
E
E
---
S
H
--
R
E
----
K
N
G
-----
K
V
L
R
V
F
F
F
-
D
Q
D
K
F
V
-
T
C
Y
L
V
--
D
EN
K
D
L
V
Q
H
A
E
Y
V
F
K
-
G
N
L
I
R
K
D
--
Y
F
S
Y
T
R
Y
--
C
S
E
Y
F
A
P
K
D
N
V
A
V
L
Y
Q
R
T
F
Y
N
E
D
G
T
P
-----
V
Y
D
I
L
M
N
Q
G
---------
K
E
-
E
V
--
Y
H
F
K
D
K
I
F
Y
G
K
Q
A
--
F
V
R
A
F
M
K
S
L
N
--
L
-
N
K
S
D
L
V
I
L
D
R
E
T
G
I
-
G
--
Q
V
V
-
F
E
-
E
A
-
Q
-
T
-
A
H
L
A
V
V
V
H
A
E
H
Y
S
-
E
N
-
A
T
N
----
E
D
Y
I
--
L
--
W
-----------------
N
-----
N
Y
------
Y
D
Y
Q
-
F
T
N
A
D
K
V
D
F
F
-
I
V
S
--
T
-
D
R
Q
N
----
E
----
V
L
Q
E
Q
F
---------------------
A
---------
K
YTQH
Q
P
K
I
V
T
I
P
-
V
G
S
I
D
S
L
T
D
S
---------------
S
-----------------------------
Q
-----------------------------
G
R
K
P
F
S
L
I
T
---
A
S
R
L
A
K
E
K
H
I
D
W
L
V
K
A
V
I
E
A
H
K
E
L
P
E
L
T
F
D
I
Y
G
S
G
G
E
-----
D
-----------
S
L
L
R
E
I
I
A
N
H
Q
A
E
D
Y
I
Q
L
K
G
----
H
-----
A
--
E
L
S
Q
I
Y
-
S
Q
Y
E
V
Y
L
T
A
S
T
-------
S
E
G
F
G
L
T
L
M
E
A
I
G
S
G
L
P
L
I
G
F
D
V
P
Y
G
N
Q
T
F
I
E
D
G
---------
Q
N
G
Y
L
-------
I
P
------
S
S
S
-------
D
HV
E
D
Q
I
K
Q
A
Y
A
A
K
I
C
Q
L
Y
Q
----
E
-
N
R
L
E
A
M
R
A
Y
S
Y
Q
-
I
A
E
G
F
L
T
K
E
I
L
E
K
W
K
K
T
V
E
E
V
L
H
-----------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
55.88
25%
52
- C1 -
5E9U
3
?
A:
[41-500]
-------------------------------------------------------------
D
--
M
I
L
A
D
N
I
Q
H
L
T
E
N
I
G
F
L
D
E
E
I
I
W
L
Y
N
Y
F
T
D
I
K
I
A
P
T
T
----------------
V
-
T
L
D
Q
-
V
----
L
A
Q
---
V
A
-
G
Q
P
----
E
R
S
E
K
E
GK
I
V
R
Y
F
Y
-
P
-
Q
D
D
Q
F
I
-
T
C
Y
L
R
QE
D
--
Q
D
F
V
E
H
V
E
Y
V
S
-
R
G
R
L
I
R
K
D
Y
F
S
Y
V
R
Y
A
S
E
Y
F
A
P
H
N
D
A
--
A
--
T
L
Y
Q
R
R
F
Y
H
E
D
G
S
V
-----
A
Y
D
M
L
-
I
E
D
G
Q
E
K
L
Y
R
F
P
D
R
-
I
F
Y
S
----------
K
A
E
--
L
V
R
Y
F
L
Q
C
L
Q
L
Q
A
-
D
D
--
V
V
I
L
D
R
E
T
G
I
-
G
--
Q
-
V
-
V
--
F
--
E
-
E
S
Q
K
A
K
L
G
V
V
V
H
A
E
H
-
F
S
-
E
N
A
SSDD
Y
-----
I
--
L
-----------------
W
-----
N
N
------
F
Y
D
Y
---
Q
F
T
N
A
D
K
V
D
F
F
I
V
A
T
-
E
A
Q
K
R
I
L
E
Q
----
Q
F
Q
H
Y
S
---------------------
D
---------
K
----
Q
P
Q
I
A
T
I
P
V
G
S
L
D
Q
L
T
Y
P
----------------
K
-----------------------------
E
-----------------------------
P
R
K
P
Y
S
M
I
T
---
A
S
R
L
A
T
E
K
H
I
D
W
L
V
A
A
T
V
Q
A
H
A
Q
L
P
E
L
T
L
D
I
Y
G
K
G
S
E
-----
E
-----------
D
K
L
R
R
R
I
E
E
A
G
A
Q
D
Y
I
R
L
K
G
----
H
----
A
D
L-
S
Q
I
Y
A
G
-
Y
E
L
Y
L
T
A
S
T
S
---------
E
G
F
G
L
T
L
M
E
A
V
G
S
G
L
P
L
I
G
F
D
V
R
Y
G
N
Q
T
F
I
D
D
G
---------
K
N
G
Y
L
L
P
V
S
SNH
V
E
------
D
Q
I
-------
I
-------
A
A
F
V
E
K
I
I
A
L
F
S
-----
Q
G
R
Q
Q
E
M
S
Q
H
S
Y
Q
-
V
A
E
N
Y
L
T
S
R
V
E
A
A
W
T
Q
L
L
K
E
V
-------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
54.39
25%
50
- C1 -
5E9T
1
?
A:
[41-500]
-------------------------------------------------------------
D
--
M
I
L
A
D
N
I
Q
H
L
T
E
N
I
G
F
L
D
E
E
I
I
W
L
Y
N
Y
F
T
D
I
K
I
A
P
T
T
----------------
V
-
T
L
D
Q
-
V
----
L
A
Q
---
V
A
-
G
Q
P
----
E
R
S
E
K
E
GK
I
V
R
Y
F
Y
-
P
-
Q
D
D
Q
F
I
-
T
C
Y
L
R
QE
D
--
Q
D
F
V
E
H
V
E
Y
V
S
-
R
G
R
L
I
R
K
D
Y
F
S
Y
V
R
Y
A
S
E
Y
F
A
P
H
N
D
A
--
A
--
T
L
Y
Q
R
R
F
Y
H
E
D
G
S
V
-----
A
Y
D
M
L
-
I
E
D
G
Q
E
K
L
Y
R
F
P
D
R
-
I
F
Y
S
----------
K
A
E
--
L
V
R
Y
F
L
Q
C
L
Q
L
Q
A
-
D
D
--
V
V
I
L
D
R
E
T
G
I
-
G
--
Q
-
V
-
V
--
F
--
E
-
E
S
Q
K
A
K
L
G
V
V
V
H
A
E
H
-
F
S
-
E
N
A
SSDD
Y
-----
I
--
L
-----------------
W
-----
N
N
------
F
Y
D
Y
---
Q
F
T
N
A
D
K
V
D
F
F
I
V
A
T
-
E
A
Q
K
R
I
L
E
Q
----
Q
F
Q
H
Y
S
---------------------
D
---------
K
----
Q
P
Q
I
A
T
I
P
V
G
S
L
D
Q
L
T
Y
P
----------------
K
-----------------------------
E
-----------------------------
P
R
K
P
Y
S
M
I
T
---
A
S
R
L
A
T
E
K
H
I
D
W
L
V
A
A
T
V
Q
A
H
A
Q
L
P
E
L
T
L
D
I
Y
G
K
G
S
E
-----
E
-----------
D
K
L
R
R
R
I
E
E
A
G
A
Q
D
Y
I
R
L
K
G
----
H
----
A
D
L-
S
Q
I
Y
A
G
-
Y
E
L
Y
L
T
A
S
T
S
---------
E
G
F
G
L
T
L
M
E
A
V
G
S
G
L
P
L
I
G
F
D
V
R
Y
G
N
Q
T
F
I
D
D
G
---------
K
N
G
Y
L
L
P
V
S
S
N
H
V
E
------
D
Q
I
-------
I
-------
A
A
F
V
E
K
I
I
A
L
F
S
-----
Q
G
R
Q
Q
E
M
S
Q
H
S
Y
Q
-
V
A
E
N
Y
L
T
S
R
V
E
A
A
W
T
Q
L
L
K
E
V
-------------------------------------------------------------------------------------------------------------------------------------------------------
39
HHSearch
41.50
17%
11
- C1 -
3S28
5
SUSY1_ARATH
A:
[406-771]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
P
D
L
I
I
G
N
Y
S
D
G
N
-
L
--
V
-
A
-
S
L
L
A
--
H
-
K
-
L
G
V
T
Q
C
T
I
A
H
A
L
E
-
K
T
-
K
Y
P
----
D
SDI--
Y
--
W
KKL--------------
D
-----
D
K
YH
F
S
C
Q
F
T
A
D
-
I
F
A
M
N
H
T
D
F
I
-
I
T
S
--
T
-
F
Q
E
I
----
A
----
G
S
K
E
T
V
G
Q
Y
E
S
H
TAFTLPGLYRVVHGI
D
V--------
F
----
D
P
K
F
N
I
V
S
-
P
G
A
D
M
S
I
Y
F
P
Y
T
-------------
E
-----------------------------
E
KRRLTKF
H
S
E
I
E
E
L
L
YSDVENKEHLCVLK
D
K
K
K
P
I
L
F
T
---
M
A
R
L
D
R
V
K
N
L
S
G
L
V
E
W
Y
G
K
N
T
R
L
R
E
L
A
N
L
V
V
V
G
G
D
R
R
-----
K
ESKD
N
E
E
K
A
E
M
K
K
M
Y
D
L
I
E
E
Y
K
L
N
G
Q
F
R
W
I
S
SQMD
R
----
V
R
N
G
E
L
Y
R
Y
I
C
D
T
K
G
A
F
V
Q
P
A
L
-------
Y
E
A
F
G
L
T
V
V
E
A
M
T
C
G
L
P
T
F
A
T
C
K
G
-
G
P
A
E
I
I
V
H
G
---------
K
S
G
F
H
-------
I
D
------
P
Y
H
-------
G
-------
D
Q
A
A
D
T
L
A
D
F
F
T
K
C
K
E
D
P
S
H
W
D
E
I
S
K
G
G
L
Q
R
I
E
E
K
Y
T
W
Q
I
Y
S
Q
R
L
L
T
L
T
G
V
Y
G
F
-----------------------------------------------------------------------------------------------------------------------------------------------------
38
HHSearch
41.40
17%
-12
- C1 -
2X6Q
-
TRET_PYRHO
A:
[123-415]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
L
-
S
S
F
D
Y
V
L
V
H
D
P
Q
P
A
-
A
--
L
-
I
-
E
F
-
Y
--
E
---
K
K
S
P
W
L
W
R
C
H
I
D
L
-
S
S
-
P
N
--------------------------------
R
-----
E
F
------
W
E
F
L
-
R
R
F
V
E
K
Y
D
R
Y
-
I
F
H
--
L
P
E
Y
V
Q
----
P
----
E
L
-------------------------
D
--------------
R
N
K
A
V
I
M
P
-
P
S
I
D
P
L
S
E
K
N
V
E
LK
Q
T
E
I
L
R
I
L
E
R
F
D
-----------------------------
V
-----------------------------
D
P
E
K
P
I
I
T
Q
---
V
S
R
F
D
P
W
K
G
I
F
D
V
I
E
I
Y
R
K
V
K
E
K
I
P
G
V
Q
L
L
L
V
G
V
M
A
H
-----
D
D
P
E
G
W
------
I
Y
F
E
K
T
L
R
K
I
G
E
D
Y
D
V
K
V
L
T
----
N
LIGV
H
A
R
-
E
V
N
A
F
Q
-
R
A
S
D
V
I
L
Q
M
S
I
-------
R
E
G
F
G
L
T
V
T
E
A
M
W
K
G
K
P
V
I
G
R
A
V
G
-
G
I
K
F
Q
I
V
D
G
---------
E
T
G
F
L
-------
V
R
--------
D
-------
A
-------
N
E
A
V
E
V
V
L
Y
L
L
K
----
H
P
E
V
S
K
E
M
G
A
K
A
K
E
R
V
R
K
N
F
I
I
T
K
H
M
E
R
Y
L
D
I
L
N
S
L
G
------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
41.36
21%
27
- C1 -
3OKP
1
PIMB_CORGL
A:
[78-381]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
E
I
I
-
R
E
-
R
E
I
D
N
V
W
F
G
A
A
A
P
L
-
A
--
L
-
M
A
G
T
-
A
--
K
-
Q
A
G
A
S
K
V
I
A
S
T
H
G
H
E
-
V
G
-
W
S
M
-------------
L
-----------------
P
-----
G
S
------
R
Q
S
L
-
R
K
I
G
T
E
V
D
V
L
-
T
Y
I
--
S
-
Q
Y
T
L
----
R
----
R
F
K
S
A
F
---------------------
G
---------
S
----
H
P
T
F
E
H
L
P
-
S
G
V
D
V
K
R
F
T
P
A
T
-------------
P
E
D
K
S
A
T
R
K
K
L
G------------------
F
-----------------------------
T
D
T
T
P
V
I
A
C
---
N
S
R
L
V
P
R
K
G
Q
D
S
L
I
K
A
M
P
Q
V
I
A
A
R
P
D
A
Q
L
L
I
V
G
S
G
R
Y
-----
E
-----------
S
T
L
R
R
L
A
T
D
--
V
S
Q
N
V
K
F
L
G
----
R
----
L
E
Y
Q
D
M
I
N
T
L
-
A
A
A
D
I
F
A
M
P
A
R
T
R
GGGLD
V
E
G
L
G
I
V
Y
L
E
A
Q
A
C
G
V
P
V
I
A
G
T
S
G
-
G
A
P
E
T
V
T
P
----------
A
T
G
L
V
-------
V
E
------
G
S
D
-------
V
-------
D
K
L
S
E
L
L
I
E
L
L
D
----
D
P
I
R
R
A
A
M
G
A
A
G
R
A
H
V
E
A
E
W
S
W
E
I
M
G
E
R
L
T
N
I
L
Q
S
E
P
R
-----------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
40.97
18%
12
- C1 -
2JJM
-
BSHA_BACAN
A:
[80-374]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
V
A
-
Q
R
-
E
N
L
D
I
L
H
V
H
Y
A
I
P
H
A
I
C
A
Y
-
L
-
A
K
-
Q
M
-
I
-
G
-
E
R
I
K
I
V
T
T
L
H
G
T
D
-
I
T
-
V
L
G
----
S
--------
D
-----------------
P
-----
S
L
------
N
N
L
I
-
R
F
G
I
E
Q
S
D
V
V
-
T
A
V
--
S
-
H
S
L
I
----
N
----
E
T
H
E
L
V
---------------------
K
---------
P
----
N
K
D
I
Q
T
V
Y
-
N
F
I
D
E
R
V
Y
F
K
R
D
M
T
Q
L
K
K
E
Y
-----
G
-----------------------------
I
-----------------------------
S
---
K
I
L
I
H
---
I
S
N
F
R
K
V
K
R
V
Q
D
V
V
Q
A
F
A
K
I
V
T
E
-
V
D
A
K
L
L
L
V
G
D
G
P
E
-----
F
-----------
C
T
I
L
Q
L
V
K
N
L
H
I
E
D
R
V
L
F
L
G
----
K
----
Q
D
--
N
V
A
E
L
L
-
A
M
S
D
L
M
L
L
L
S
E
-------
K
E
S
F
G
L
V
L
L
E
A
M
A
C
G
V
P
C
I
G
T
R
V
G
-
G
I
P
E
V
I
Q
H
G
---------
D
T
G
Y
L
-------
C
E
------
V
G
D
-------
T
-------
T
G
V
A
D
Q
A
I
Q
L
L
K
----
D
E
E
L
H
R
N
M
G
E
R
A
R
E
S
V
Y
E
Q
F
R
S
E
K
I
V
S
Q
Y
E
T
I
Y
Y
D
V
L
R
-----------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
40.64
18%
8
- C1 -
2QZS
3
GLGA_ECOLI
A:
[120-477]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
S
G
L
D
-
P
F
-
W
R
P
D
V
V
H
A
H
D
W
H
A
G
-
L
A
P
A
-
Y
-
L
A
-
A
--
R
-
G
-
R
P
A
K
S
V
F
T
V
H
N
L
A
-
Y
Q
-
G
M
F
----
Y
-----
A
HH
M
NDIQLPWSFFNIHGLEF
N
-----
G
Q
------
I
S
F
L
-
K
A
G
L
Y
Y
A
D
H
I
-
T
A
V
--
S
-
P
T
Y
A
----
R
----
E
I
T
E
P
Q
FAY------------------
G
M
E
G
L
L
Q
Q
R
H
R
----
E
G
R
L
S
G
V
L
-
N
G
V
D
E
K
I
W
S
P
E
T
-------------
D
LLLA
S
R
Y
T
RDTLEDK
A
E
N
K
R
Q
L
Q
I
A
M
GLK
V
-----------------------------
D
D
K
V
P
L
F
A
V
---
V
S
R
L
T
S
Q
K
G
L
D
L
V
L
E
A
L
P
G
L
L
E
Q
--
G
G
Q
L
A
L
L
G
A
G
D
P
V
L
---
Q
-----------
E
G
F
L
A
A
A
A
E
Y
P
G
Q
V
G
V
-
Q
I
G
----
Y
----
H
E
A
-
F
S
H
R
I
M
-
G
G
A
D
V
I
L
V
P
S
R
-------
F
E
P
C
G
L
T
Q
L
Y
G
L
K
Y
G
T
L
P
L
V
R
R
T
G
-
G
L
A
D
T
V
S
D
C
S
L
E
N
L
A
D
GV
A
S
G
F
V
-------
F
E
------
D
S
N
-------
A
-------
W
S
L
L
R
A
I
R
R
A
F
V
L
W
S
-
R
P
S
L
W
R
F
V
Q
R
Q
A
---
M
A
M
D
F
S
W
Q
V
A
A
K
S
Y
R
E
L
Y
Y
R
L
K
------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
39.93
29%
-34
- C1 -
3MBO
2
BSHA_BACAN
A:
[228-381]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
E
S
E
K
I
L
I
H
--
I
S
N
F
R
K
V
K
R
V
Q
D
V
V
Q
A
F
A
K
I
V
T
E
V
-
D
A
K
L
L
L
V
G
D
G
P
E
-----
F
-----------
C
T
I
L
Q
L
V
K
N
L
H
I
E
D
R
V
L
F
L
G
----
K
----
Q
D
--
N
V
A
E
L
L
-
A
M
S
D
L
M
L
L
L
S
E
-------
K
E
S
F
G
L
V
L
L
E
A
M
A
C
G
V
P
C
I
G
T
R
V
G
-
G
I
P
E
V
I
Q
H
G
---------
D
T
G
Y
L
-------
C
E
------
V
G
D
-------
T
-------
T
G
V
A
D
Q
A
I
Q
L
L
K
----
D
E
E
L
H
R
N
M
G
E
R
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
39.35
16%
-4
- C1 -
4XSO
2
?
B:
[95-384]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
E
Y
D
L
I
Y
A
N
T
Q
K
A
L
V
V
--
G
-
A
-
I
A
-
S
--
F
-
I
-
A
R
R
P
L
V
Y
H
L
H
D
I
L
-
S
P
-
E
H
F
----
S
--------------------------
Q
-----
T
N
------
L
R
V
A
V
N
L
A
N
R
F
A
S
L
V
-
I
A
N
--
S
-
Q
A
S
Q
----
T
----
A
F
I
Q
A
G
---------------------
G
---------
R
----
A
E
L
T
K
V
I
Y
-
N
G
F
D
I
N
L
Y
K
T
S
P
-------------
S
DISKLRQQL--------------------
G
-----------------------------
V
A
N
N
F
V
V
G
H
---
F
S
R
L
S
P
W
K
G
Q
H
I
L
I
D
A
L
A
Q
C
P
---
P
Q
V
T
A
I
L
V
G
D
A
L
F
GEQDY
V
-----------
K
E
L
H
Q
Q
I
T
R
L
G
L
E
N
R
V
K
F
L
G
----
F
----
R
A
--
D
I
P
Q
L
M
-
A
A
C
D
L
V
A
H
T
S
T
A------
P
E
P
F
G
R
V
I
V
E
A
M
L
C
G
K
P
V
V
A
A
K
A
G
-
G
A
M
E
L
V
E
H
G
---------
V
N
G
F
L
-------
T
T
------
P
G
E
-------
S
-------
Q
E
L
A
N
I
I
N
T
C
I
E
----
D
T
Q
K
T
A
T
I
A
S
N
A
Q
A
I
A
S
Q
R
F
D
V
V
T
I
N
Q
Q
I
A
E
T
L
S
S
L
-------------------------------------------------------------------------------------------------------------------------------------------------------