@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu36190: (2016-07-31 )
MSKVFESKSLIEEAKSRKKQYETLEEQLNTLKKAFQGVADLGDNFKGNGADNIKDFFQGQAEIVDSWLTLVSAQIAFLNGISGDIKDQELNDSYVETSFLDHELPNGDLKASEIVSAHKEEIDSILSGISDIIDLDMYTLDDYADKMGDAQKIRRDTITAVDKLDESLTTEYQNLESLDNAVLTKYSVLMQATSNGKSASPMYYDKKAFHSNEVYKSVIEVENQGTTYIDAKTQQAEARRLQEKAEEEANKPWYEKTWDGVCNFTGEVTGYYDYKRATEGVDPVTGEKLSTAERVTAGAMAAAGFIPVVGWAGRAFKGGKAIYKTGKAAIAAEHALDAYKTGKSLDILKMTEMGAYGLVASNGFSEAVTGRDMFGNKVSEEKRKQGALEAITIIGGAGLAHYFDRLYQKNAPYVNKVSNESLISNIAKTTEEKQTRLQYLRNKHGVLSKEDLHHRINLRAEVLNELSRIKSSGLTKKQRGPAVAGVLDKKTGNYYFGINNIDGKPPKVLHPLIHDRIVNMPTELKEGYIKTSGAGSHAEVNALNEALLQRPDADLKDLMVYVVSARKINKKMPEGVPMPRCPHCEYITQNTNYIPEALKYGK
Atome Classification :
(20 SA)
------------------.........10--........20....----....30......------..40........50.----.......60........70.........80----------.........--90........100----.......110..----.....120.......130---..-......140-......----..150........160.......170...-....--180.......190.......200.......210.......220.......230.......240.......250.......260.....-----..270....----.---..280.......290-.---.......300--.......310.......320.......330.......340.......350.......360.....--..370--...--..-----...380....-------...390....-------...400.......410...-....420.......430.......440.-----......450...-.....460..------.....470.......480..------.....490.......500.....-----------..510.......520.....--.-------.530.....--..540.....-----..550------.-.-----.....-.560..-.....570-......--------.580.......590.......600-----------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------------MS
K
V
F
E
S
K
S
L
I
--
E
E
A
K
S
R
K
K
Q
Y
E
T
L
E
----
E
Q
L
N
T
L
K
K
A
F
Q
G
------
V
A
D
LGDNFKGNG
A
D
N
----
I
K
D
F
F
Q
G
Q
A
E
I
V
D
S
W
L
T
L
-
V
S
A
Q
I
A
F
LNG-----------ISGDIKDQE--LN
D
S
Y
V
ETSFLDH----ELPNGDL
K
A
S
E
I
----
V
S
A
H
K
E
E
I
D
S
I
L
S
G
I
S
D
----
I
I
-
D
L
D
M
Y
T
L
D
--
D
Y
A
D
KM----G
D
A
-
Q
K
I
R
R
D
T
I
T
A
V
D
K
L
D
E
S
L
T
T
E
Y
Q
N
L
-
E
S
L
D
--
N
A
V
L
T
K
Y
S
V
L
M
QATSNGKSASPMYYDKKAFH
S
N
E
V
Y
K
S
V
I
E
VENQG
T
T
Y
I
DAK
T
Q
Q
A
E
A
R
R
L
Q
E
K
A
E
E
EANKPW
Y
E
K
T
WDGVCNFTGE-----V
T
G
Y
YDYKR----A---TEGVDPVTGEKLS
T
--
A
---
E
R
V
T
A
G
A
M
AA--AGFIPVVGWAGRAFKGGK
A
I
Y
KTG
K
A
A
I
A
A
E
H
A
L
D
A
Y
KTGKS
L
D
I
L
K
M
TEMGA
Y
G
L
V
ASNGFSEA--VTGR---DMF--GN-----KV
S
E
E
K
R
KQG-------A
L
E
A
I
T
I
IGG-------
A
G
L
A
H
Y
F
D
R
L
Y
QKNAP
Y
V
N-KVS
N
E
S
L
I
S
N
I
A
K
T
T
E
E
K
Q
T
R
L
Q
Y
L
R
N
K-----HGVL
S
K
E
D
-
L
H
H
-
R
I
N
L
R
A
E
V
L
N
------
E
L
S
R
I
K
SSGLTKKQRGPAVA------
G
V
L
DKKTG
N
Y
Y
F
G
I
NNIDGKP
P
K
-----------
V
L
H
P
L
I
H
D
R
I
VNM
P
T
E
L
KE
G
--
Y
-------
I
KTSGAGSH--
A
E
V
N
A
L
N
E
A
L
-----LQRP-------D-A-----
D
L
K
D
L
-
M
V
Y
V
V
S
-
A
R
K
INKKM-PEGVPM--------PRCPHC
E
Y
ITQNTNY
I
P
E
A
LKYGK-----------------
45
Fugue
56.50
16%
25
- C3 -
4IUW
16
?
A:
[4-633]
LPRIQDD
L
Y
L
A
V
N
G
E
W
Q
A
K
T
P
I
P
P
D
K
S
V
V
S-
A
D
S
N
L
T
D
D
I
R
Q
K
L
V
----
A
D
L
S
T
M
T
K
T
-------------
A
K
T
L
P
L
Q
Y
A
A
R
----
L
F
A
K
A
N
D
Q
T
R
R
Q
Q
L
G
I
E
P
-
V
R
D
R
I
S
F
L
M
A
-----------
L
T
---
T
L
D
Q
--
F
R
S
A
M
P
K
L
V
A
D
Q
Y
----
V
L
P
-----
I
S
P
Y
----
V
D
A
D
M
H
D
A
E
H
N
I
L
N
L
G
G
P
D
T
I
L
P
-
D
A
A
M
Y
N
Q
E
D
A
E
N
A
A
D
L
----
A
A
W
-
S
Q
M
A
A
A
M
L
A
A
V
G
F
S
Q
T
D
Q
T
A
Y
V
E
A
A
-
K
R
F
D
--
R
R
L
A
D
Y
V
P
A
N
V
D
L
-----
A
V
D
S
T
Y
D
N
P
L
S
W
Q
A
F
E
D
A
A
G
Y
L
G
I
P
Q
A
F
A
T
Y
M
P
Q
T
P
A
K
V
N
A
V
V
-----------
P
A
Y
L
P
H
L
S
K
L
L
T
-
P
D
N
-----
Y
S
E
W
H
A
W
M
V
----
I
---
N
E
L
L
T
C
A
T
--
Y
L
S
D
--
D
---
L
R
Q
L
A
G
Q
Y
D
R
F
L
A
G
Q
P
E
A
S
S
W
T
K
H
A
F
G
I
A
N
E
Y
F
D
D
V
I
G
Q
Y
Y
G
Q
T
Y
F
G
A
D
A
K
A
D
V
T
A
M
V
K
Q
I
L
A
Q
Y
R
V
Q
L
E
N
N
T
W
L
S
P
--
A
T
K
Q
---
K
A
M
---
R
-----
K
L
A
T
M
Q
V
K
M
G
YPARLFS
L
Y
D
H
L
S
V
D
V
D
-------
D
D
L
L
T
A
I
L
K
L
S
A
Q
T
Q
A
F
W
F
-
K
Q
L
G
Q
T
V
D
R
N
------------
Q
W
N
M
P
G
-----
H
L
V
N
A
S
Y
D
P
L
K
N
-
D
I
T
F
P
A
G
I
L
Q
PPYYSL
K
W
T
R
A
E
N
L
G
G
T
G
A
T
I
G
H
E
I
S
------
H
S
F
D
N
N
G
A
L
Y
-----
D
E
Y
G
N
L
H
N
-----------
W
W
T
P
A
D
K
Q
A
F
D
Q
L
V
K
A
M
A
A
Q
--
F
DGRDYEG
V
K
V
N
G
T
L
T
V
--
S
E
N
M
A
D
N
A
G
M
D
V
A
L
A
L
L
G
D
-------
Q
-
P
-----
D
V
K
D
L
-
Q
A
F
F
I
T
Y
A
R
S
W
A
T
K
M
R
P
E
R
A
K
T
V
L
R
QDVHA
P
A
T
L
R
V
N
V
P
V
Q
N
F
P
A
W
Y
Q
A
F
N
V
Q
P
QDGMYRQPQK
R
L
T
I
WHQ
43
Fugue
55.60
18%
83
* C2 *
4UNM
4
?
A:
[8-615]
--------------------
K
Y
H
Q
Y
K
I
N
Q
--
P
E
Y
K
A
A
N
G
K
W
E
I
I
E
F
PEK
Y
R
Q
N
T
I
H
A
A
L
L
R
TG
K
V
L
M
V
A
G
S
G
N
N
Q
D
N
S
D
D
K
Q
Y
D
T
R
I
W
D
P
V
K
G
T
I
K
K
V
P
T
P
S
D
L
F
C
T
G
H
T
Q
L
A
N
G
N
L
L
--------
I
A
G
G
T
K
R
Y
E
--
K
L
K
G
D
V
T
K
A
G
G
L
M
----
V
V
H
N
E
N
P
D
K
P
I
T
----
L
P
A
-----
G
T
K
F
T
G
K
E
N
---------
G
K
T
F
V
S
--
K
D
P
V
L
V
----
P
R
A
-
E
K
V
R
N
D
P
G
L
G
R
I
Y
V
E
A
Q
K
S
G
S
A
Y
E
T
-
G
T
E
D
--
N
Y
R
V
Q
G
L
S
G
A
D
A
R
N
T
Y
G
I
A
-
Q
K
L
A
L
D
K
K
D
F
Q
G
---
I
R
D
A
F
E
F
D
P
V
A
E
K
Y
I
K
V
D
-------------------
P
M
H
E
A
R
W
Y
P
T
L
T
T
L
G
D
G
K
I
L
S
V
S
G
L
D
D
I
G
Q
LVPG
K
---
N
E
V
Y
D
P
K
T
K
-
A
W
T
Y
--
T
---
D
K
V
R
Q
F
P
T
Y
P
--
A
L
F
L
---------
M
Q
N
G
K
I
F
Y
-
S
G
-----
A
N
A
G
Y
G
P
D
D
V
G
R
T
P
G
V
W
D
---------
V
E
T
N
K
F
T
K
V
P
G
M
S
D
A
---
N
M
L
ET
A
N
-----
T
V
L
L
P
P
A
Q
D
----------
E
K
Y
M
V
I
G
G
-------
G
G
V
G
E
--
S
K
L
S
S
E
K
T
R
I
A
D
L
K
A
D
D
P
K
F
V
D
G
P
S
L
E
K
G
T
R
Y
P
Q
A
S
I
L
P
D
D
-----
S
V
L
V
S
G
G
S
-
Q
D
Y
-
R
G
R
G
D
S
N
I
L
Q
------
A
R
L
Y
H
P
D
T
N
E
F
E
R
V
A
D
P
L
V
G
R
N
Y
H
S
G
S
I
L
L
P
D
G
R
L
M
F
F
G
S
D
S
L
Y
A
D
K
A
N
T
K
P
G
K
F
EQ
R
I
E
I
Y
T
P
P
Y
L
Y
R
--
D
S
R
P
D
L
S
G
G
P
Q
T
-------
I
A
R
G
G
S
G
T
F
T
S
R
A
A
S
T
V
K
K
V
R
-----
L
I
R
P
SASTHVT
D
-
V
-----
D
Q
R
S
I
A
L
D
F
K
A
D
-
G
D
K
L
T
V
T
V
-
P
S
G
K
N
L
--------
V
Q
S
G
W
Y
M
M
F
V
T
D
G
E
G
T
P
S
K
A
E
W
V
R
V
P---------------
46
Fugue
53.68
18%
14
- C2 -
4TR2
8
?
A:
[54-627]
----------------------
D
D
V
H
K
I
I
--
S
E
L
R
F
L
Q
K
V
E
T
I
L
E
----
S
S
-
N
M
S
V
S
D
V
E
A
------
D
A
N
A
Y
N
P
D
R
D
A
P
K
E
E
----
L
Q
K
L
Q
D
K
K
S
------
L
R
L
-
I
V
S
E
-----------------------
N
H
A
--
T
S
P
S
F
F
E
E
S
L
L
Q
E
----
D
V
V
S
F
I
Q
S
K
G
K
L
----
S
N
-----
L
K
N
L
K
S
M
I
I
D
----
L
N
S
D
M
T
D
E
E
L
A
--
E
Y
I
S
L
L
----
E
R
K
G
A
L
I
E
S
D
K
L
V
G
A
D
Y
---
K
F
N
D
E
Y
R
N
L
Q
W
G
L
D
--
L
A
R
L
D
E
T
-------------------
Q
D
L
I
N
A
N
R
V
S
V
T
K
I
C
V
I
D
S
G
I
D
Y
----
N
H
P
D
L
R
N
N
I
D
V
N
V
K
E
L
H
G
R
K
G
V
D
D
D
S
N
G
V
---
V
D
D
-----
V
Y
G
A
N
F
V
N
N
----
S
---
G
D
P
M
D
D
-----------------
N
Y
H
G
T
H
V
--
S
G
I
I
S
A
V
G
N
N
G
I
G
I
V
G
V
-----
D
G
H
S
K
L
V
I
C
K
A
L
D
Q
H
K
L
G
R
L
G
D
M
F
K
C
I
D
Y
C
I
S
R
--------------------------------------------------
Q
A
H
M
I
N
G
S
-------
F
S
F
D
E
Y
-
S
N
I
F
N
A
S
V
E
H
L
R
-
S
L
G
I
L
F
F
V
S
--
A
S
N
C
A
-----------------
H
D
K
L
S
K
P
D
-
I
A
K
C
D
L
A
V
N
H
R
Y
P
P
------
I
L
S
K
T
H
N
N
-------
V
I
A
V
A
------
N
L
K
R
D
L
D
E
S
Y
S
L
S
V
N
S
F
Y
S
N
I
Y
C
-----------
Q
L
A
A
P
G
T
N
I
Y
S
T
T
P
M
N
---
N
--
Y
-------
R
K
L
N
G
T
S
M
A
--
S
P
H
V
A
A
I
A
S
I
-----
V
R
S
I
-------
N
-
P
-----
N
L
T
Y
L
-
Q
I
V
E
I
L
-
R
N
A
I
V
K
-
L
-
P
S
L
T
E
R
--------
V
S
W
G
G
Y
V
D
I
L
R
A
V
N
L
A
I
D
S
K
---------------------
30
HHSearch
45.99
12%
-145
- C4 -
4I0X
2
?
B:
[10-90]
---------------------
S
F
D
L
D
H
I
E
--
Q
V
T
S
R
A
R
G
F
K
E
F
V
T
----
E
N
L
D
Q
L
E
S
R
A
Q
K
------
L
V
Q
-
S
G
Q
W
A
G
A
A
A
A
A
----
Y
S
Q
A
H
K
E
W
M
D
A
A
R
E
L
V
E
G
-
L
S
Q
M
E
E
A
A
R
T
-----------
A
H
G
A
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
45.75
13%
-232
- C4 -
4J42
3
?
A:
[9-87]
----------------------
I
T
P
E
E
L
E
--
R
I
A
G
N
F
K
N
A
A
G
E
A
Q
----
S
Q
I
N
R
L
E
G
D
I
N
S
------
L
---
E
G
Q
W
A
G
A
T
Q
A
K
----
F
R
G
E
F
I
Q
S
K
Q
A
M
Q
Q
F
I
P
I
-
L
E
G
I
S
T
D
L
K
R
-----------
I
A
D
K
F
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
Fugue
43.26
15%
33
* C3 *
2BVL
8
TOXB_PEPDI
A:
[1-543]
------------------
M
S
L
V
-
N
R
K
Q
L
E
--
K
M
A
N
V
R
---
F
R
T
Q
E
----
D
E
Y
V
A
I
L
D
A
L
E
E
------
Y
H
N
M
S
E
N
T
V
V
E
K
Y
L
K
----
L
K
D
I
N
S
L
T
D
I
C
I
D
T
Y
------------------------------------------------------------
K
K
S
G
R
----
N
K
A
L
K
K
F
K
E
Y
L
V
T
E
V
L
E
----
L
K
-
N
N
N
L
T
P
V
E
--
K
N
L
H
F
V
----
W
I
G
-
G
Q
I
N
D
T
A
I
N
Y
I
N
Q
W
K
D
V
------------------------------
N
S
D
Y
N
V
N
V
F
Y
D
S
N
A
F
L
I
N
T
L
K
K
T
V
V
E
---------
S
A
I
N
D
T
L
E
S
F
R
E
N
L
N
D
P
R
F
D
Y
N
K
F
F
R
K
R
M
E
I
I
Y
D
K
Q
K
N
-----
F
I
N
Y
Y
K
A
Q
R
----
E
E
NP
E
L
I
I
D
D
I
V
K
T
Y
L
S
N
--
E
YSK
E
I
D
E
L
N
T
Y
I
E
--
E
S
L
N
K
I
T
Q
N
S
G
N
D
V
R
N
F
G
E
F
K
N
G
E
S
F
N
L
Y
E
Q
E
L
V
E
R
W
N
L
A
A
A
S
D
I
L
R
I
S
A
L
K
E
I
G
G
M
Y
L
D
V
D
M
L
P
--
G
I
Q
P
---
D
L
F
--
E
S
IEKPS
S
V
T
V
D
F
W
E
M
T
-------
K
L
E
A
I
M
K
Y
K
E
YIPEYTS
E
H
F
D
M
L
D
E
E
V
Q
S
S
F
E
S
V
L
A
-
S
K
S
D
K
S
E
I
F
S
S
L
G
D
M
E
A
S
P
L
E
V
K
I
A
F
N
S
KGIIN
Q
G
L
I
S
V
K
D
-
S
Y
C
-
S
N
L
I
V
K
Q
I
E
N
------
R
Y
K
I
L
N
N
S
L
N
P
A
I
S
E
D
N
D
F
N
------
T
T
T
N
T
F
I
D
S
I
M
A
E
A
N
A
D
N
G
R
F
M
M
-----------
E
L
G
K
Y
L
R
---
V
G
F
F
P
D
V
K
-
T
--
T
-------
I
N
L
S
G
--
P
E
--
A
Y
A
A
A
Y
Q
D
L
L
-----
M
F
K
E
-------
G
-
S
MNIHL
I
E
A
D
L
-
R
N
F
E
I
S
-
K
T
N
I
S
Q
S
T
-
E
Q
E
M
A
S
--------
L
W
S
F
D
D
A
R
A
K
A
Q
F
E
E
Y
K
R
N
Y
F
E
G
A
L----------------
34
HHSearch
42.81
9%
-131
- C4 -
3FAV
3
ESXB_MYCTU
A:
[12-85]
---------------------------
L
A
--
Q
E
A
G
N
F
E
R
I
S
G
D
L
K
----
T
Q
I
D
Q
V
E
S
T
A
G
S
------
L
---
Q
G
Q
W
R
G
A
A
G
T
A
----
A
Q
A
A
V
V
R
F
Q
E
A
A
N
K
Q
K
Q
E
-
L
D
E
I
S
T
N
I
R
Q
-----------
A
G
V
Q
Y
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
42.44
10%
-194
- C4 -
3OGI
-
ES6L6_MYCTU
A:
[13-69]
--------------------------------
H
G
A
M
I
R
A
Q
A
G
L
L
E
----
A
E
H
Q
A
I
V
R
D
V
L
A
------
A
G
------------
A
----
C
Q
E
F
I
T
Q
L
G
R
N
F
Q
V
I
Y
E
Q
-
A
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
42.36
30%
-198
- C4 -
1U5P
-
SPTN1_CHICK
A:
[148-200]
-------------------------------------
R
K
K
H
K
R
L
E
----
A
E
L
A
A
H
E
P
A
I
Q
G
------
V
L
D
T
G
K
K
L
S
D
D
N
T
I
G
----
K
E
E
I
Q
Q
R
L
A
Q
F
V
D
H
W
K
E
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
41.26
30%
-170
- C4 -
1AJ3
-
A:
[46-98]
-------------------------------------
R
K
K
H
K
R
L
E
----
A
E
L
A
A
H
E
P
A
I
Q
G
------
V
L
D
T
G
K
K
L
S
D
D
N
T
I
G
----
K
E
E
I
Q
Q
R
L
A
Q
F
V
D
H
W
K
E
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
41.17
11%
-129
- C4 -
4LWS
5
?
A:
[37-118]
---------------------
A
V
D
R
A
A
M
A
--
Q
A
A
Q
D
I
E
Q
S
A
N
A
I
R
----
G
M
Q
N
Q
L
A
S
A
K
D
Q
------
L
---
R
S
H
W
E
G
D
A
S
M
A
----
F
E
A
V
F
N
R
F
N
E
D
F
S
R
V
L
K
A
-
L
D
G
M
H
E
S
L
V
Q
-----------
T
R
I
T
Y
E
A
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
40.23
14%
-117
- C4 -
4I0X
-
?
A:
[3-77]
-------------------------
D
E
V
G
--
A
L
S
K
F
A
A
S
L
A
D
Q
M
R
----
A
G
S
N
S
L
D
R
D
V
Q
S
------
L
---
F
G
V
W
K
G
S
A
A
D
A
----
Y
R
S
G
W
D
E
M
Q
D
G
A
T
K
V
W
N
A
-
L
T
D
I
A
S
T
L
G
S
-----------
N
A
A
A
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
Fugue
39.84
17%
59
- C1 -
4C3X
9
?
A:
[23-530]
-------------------
D
W
T
S
E
C
D
V
L
V
V
G
S
G
G
G
A
L
T
G
A
Y
T
A
A
A
----
Q
G
L
T
T
I
--
V
L
E
K
------
T
D
R
F
G
G
T
S
A
Y
S
G
A
S
I
WL--
P
G
T
Q
V
Q
E
R
A
G
L
P
D
S
T
E
N
A
-
R
T
Y
L
R
A
L
L
G
D
-----------
A
E
S
E
R
Q
D
A
Y
--
V
E
T
A
P
A
V
V
A
L
L
E
Q
----
N
-
P
N
I
E
F
E
F
R
A
F
----
P
D
Y
Y
K
A
E
G
R
M
D
T
G
R
S
I
N
----
P
L
-
D
L
D
P
A
D
I
G
--
D
L
A
G
K
-----------
V
R
P
E
-------
L
D
Q
D
R
T
G
Q
D
H
A
P
-
G
P
M
I
G
G
R
A
L
I
G
R
L
L
A
A
V
Q
S
T
G
K
A
E
L
R
T
E
S
V
L
T
S
L
I
V
E
D
G
R
V
V
G
A
E
V
E
S
G
G
--------
E
T
Q
R
I
K
A
N
R
-------------------
G
V
L
M
A
A
G
G
-----
I
E
G
N
-
A
E
M
R
----
E
---
Q
A
G
T
P
---
G
K
A
I
W
S
MG
P
---
F
G
A
N
T
G
D
A
I
S
--
A
G
I
---------
A
V
G
G
A
T
A
L
L
D
Q
A
W
F
C
P
G
V
E
Q
-----
P
D
G
S
A
A
F
M
V
G
V
R
G
----
G
L
V
V
D
S
A
G
E
R
Y
--
L
N
E
S
LP
Y
D
Q
F
--
G
R
-----
A
M
D
A
H
D
D
N
G
S
-------
A
V
P
S
F
M
I
F
----------------
D
S
R
E
G
G
G
L
P
-
A
I
-
C
I
P
N
T
A
P
A
K
H
L
E
A
G
T
W
V
G
A
D
T
L
E
E
L
A
A
K
-----
T
G
L
P
------
A
D
-
A
L
R
S
T
V
E
K
F
N
------
D
A
A
K
L
G
V
D
E
E
F
H
R
G
E
D
P
Y
D
A
------
F
F
C
P
P
N
G
G
A
N
A
-
A
L
T
A
I
E
N
G
P
F
Y
-----------
A
A
R
I
V
L
S
D
L
---------------------------
G
T
K
--
G
G
L
V
T
D
V
N
G
R
-----
V
L
R
A
-------
D
G
S
-----
A
I
D
G
L
-
Y
A
A
G
N
T
-
S
A
S
L
S
G
R
F
----
Y
P
G
--------
P
G
V
P
L
G
T
A
M
V
F
S
Y
R
A
A
Q
D
M
A
K
--------------------
21
HHSearch
39.68
8%
-80
- C4 -
3FAV
4
ESXA_MYCTU
B:
[9-80]
--------------------------
G
I
E
--
A
A
A
S
A
I
Q
G
N
V
T
S
I
H
----
S
L
L
D
E
G
K
Q
S
L
T
K
------
L
---
A
A
A
W
G
G
S
G
S
E
A
----
Y
Q
G
V
Q
Q
K
W
D
A
T
A
T
E
L
N
N
A
-
L
Q
N
L
A
R
T
I
S
E
-----------
A
G
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
37.72
16%
-70
- C4 -
3GWK
1
?
C:
[7-89]
---------------------
K
L
T
P
E
E
L
R
--
S
S
A
Q
K
Y
T
A
G
S
Q
Q
V
T
----
E
V
L
N
L
L
T
Q
E
Q
A
V
------
I
---
D
E
N
W
D
G
S
T
F
D
S
----
F
E
A
Q
F
N
E
L
S
P
K
I
T
E
F
A
Q
L
-
L
E
D
I
N
Q
Q
L
L
K
-----------
V
A
D
I
I
E
Q
T
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
36.50
21%
-6
- C- -
1U4Q
-
A:
[1808-1979]
-------------------------------------
R
K
K
H
K
R
L
E
----
A
E
L
A
A
H
E
P
A
I
Q
G
------
V
L
D
T
G
K
K
L
S
D
D
N
T
I
G
----
K
E
E
I
Q
Q
R
L
A
Q
F
V
D
H
W
K
E
L
---
K
Q
L
A
A
A
R
G
Q
R
L
E
E
S
L
E
Y
Q
Q
F
V
A
N
V
E
E
E
E
A
W
I
N
E
K
M
T
L
V
A
S
E
D
Y
GDTL
A
A
I
Q
G
L
L
K
K
H
E
A
F
E
T
D
F
T
V
H
K
D
R
V
N
D
V
C
A
N
G
E
D
----
L
I
-
K
K
N
N
H
H
V
E
--
N
I
T
A
K
M
K
G
L
K
G
K
V
-
S
D
L
E
K
A
A
A
Q
R
K
A
K
L
D
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
36.09
11%
-99
- C4 -
4LWS
10
?
B:
[12-91]
---------------------
R
A
N
F
G
G
L
S
--
E
G
E
A
Q
F
S
M
T
A
R
A
L
L
----
D
E
L
T
D
L
E
G
K
L
R
A
------
K
---
L
D
R
W
D
G
D
A
Q
A
A
----
Y
W
N
Y
Q
K
E
W
D
A
A
A
K
D
M
Q
N
V
-
V
A
Q
L
G
V
A
I
R
E
-----------
A
H
D
N
Y
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
35.85
11%
-69
* C4 *
3ZBH
3
?
A:
[9-90]
----------------------
L
T
P
E
E
L
R
--
G
V
A
R
Q
Y
N
V
E
S
S
N
V
T
----
E
L
I
A
R
L
D
Q
M
S
H
T
------
L
---
Q
G
I
W
E
G
A
S
S
E
A
----
F
I
Q
Q
Y
Q
E
L
R
P
S
F
E
K
M
A
V
L
-
L
N
E
V
G
Q
Q
L
H
N
-----------
S
A
T
I
L
E
D
T
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
35.83
16%
-63
- C4 -
2VS0
4
ESXA_STAAM
A:
[6-85]
----------------------
M
S
P
E
E
I
R
--
A
K
S
Q
S
Y
G
Q
G
S
D
Q
I
R
----
Q
I
L
S
D
L
T
R
A
Q
G
E
------
I
---
A
A
N
W
E
G
Q
A
F
S
R
----
F
E
E
Q
F
Q
Q
L
S
P
K
V
E
K
F
A
Q
L
-
L
E
E
I
K
Q
Q
L
N
S
-----------
T
A
D
A
V
Q
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
35.52
22%
-75
- C4 -
1M7L
-
SFTPD_HUMAN
A:
[1-40]
---------------------------
G
L
--
P
D
V
A
S
L
R
Q
Q
V
E
A
L
Q
----
G
Q
V
Q
H
L
Q
A
A
F
S
Q
------
Y
K
K
V
E
L
F
P
N
G
G
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------