@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu36250: (2016-07-31 )
MALRKNRGSRMQRNVIAMTEPKSLNSEQYRTIRTNIEFASVDRQMKSVMITSACPGEGKSTTAANLAVVFAQQGKKVLLIDADLRKPTVHTAFFLENTVGLTSVLLKKSSMEQAVQASNEKHLDVLTSGPIPPNPAELLSSKWMKELAYEACAAYDMVIFDTPPILAVADAQILGNVADGSVLVISSGKTEKEQAAKAKEALATCKSKLLGAIMNGKKLSKHSEYGYYGTKDNFMQK
Atome Classification :
(20 SA)
------------------------.........10........20........30........40........50........60........70........80........90..------...-.-.--.100.......110......-.120.......130.......140.......150--.......160.......170.......180..----...-..190.......200.......210.......220-.......230.....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------------------MALRKNRGSR
M
Q
R
N
V
I
A
MTEPKSL
N
S
E
Q
Y
R
T
I
RTN
I
E
F
A
S
V
D
R
Q
M
K
S
V
M
I
TSACPGEGKSTTAA
N
L
A
V
V
F
AQQG
K
K
V
L
L
I
DADLRKP
T
V
H
T
A
F
------
F
LE-N-T--V
G
L
T
S
V
L
L
K
K
S
S
M
E
Q
A
V
Q
AS-NEK
H
L
D
V
LTSGPIPP
N
P
A
E
L
L
S
S
K
W
M
K
E
L
A
Y
E
A
C
--
A
AY
D
M
V
I
FDTPP
I
L
A
V
A
D
A
Q
I
LGNVAD
G
S
V
L
V
----
I
SS-GKT
E
K
E
Q
A
A
K
A
K
E
A
L
A
T
C
K
S
K
L
L
G
A
I
MN
G
K
KLSKH-SEYGYYGTKDNFMQK
2
PsiBlast_PDB
83.22
43%
-98
- C2 -
2VED
2
?
A:
[47-267]
---------------------------------
R
S
T
S
S
L
I
V
H
E
Q
P
K
S
P
I
S
E
K
F
R
G
I
R
S
N
I
M
F
A
N
P
D
S
A
V
Q
S
I
V
I
T
S
E
A
P
G
A
G
M
S
T
I
A
A
N
L
A
V
A
Y
A
Q
A
G
Y
K
T
L
I
V
D
G
D
M
R
K
P
T
Q
H
Y
I
F
------
N
L
P
-
N
-
N
--
E
G
L
S
S
L
L
L
N
W
S
T
Y
Q
D
S
I
I
S
T
-
E
I
E
D
L
D
V
L
T
S
G
P
I
P
P
N
P
S
E
L
I
T
S
R
A
F
A
N
L
Y
D
T
L
L
--
M
N
Y
N
F
V
I
I
D
T
P
P
V
N
T
V
T
D
A
Q
L
F
S
K
F
T
G
N
V
V
Y
V
----
V
N
S
-
E
N
N
N
K
D
E
V
K
K
G
K
E
L
I
E
A
T
G
A
K
L
L
G
V
V
L
N
R
M
P
K
D
K
S
A
S
Y
Y
A
Y
Y
G
--------
22
PsiBlast_CBE
82.77
43%
-99
- C2 -
2VED
2
?
B:
[47-269]
---------------------------------
R
S
T
S
S
L
I
V
H
E
Q
P
K
S
P
I
S
E
K
F
R
G
I
R
S
N
I
M
F
A
N
P
D
S
A
V
Q
S
I
V
I
T
S
E
A
P
G
A
G
M
S
T
I
A
A
N
L
A
V
A
Y
A
Q
A
G
Y
K
T
L
I
V
D
G
D
M
R
K
P
T
Q
H
Y
I
F
------
N
L
P
-
N
-
N
--
E
G
L
S
S
L
L
L
N
W
S
T
Y
Q
D
S
I
I
S
T
-
E
I
E
D
L
D
V
L
T
S
G
P
I
P
P
N
P
S
E
L
I
T
S
R
A
F
A
N
L
Y
D
T
L
L
--
M
N
Y
N
F
V
I
I
D
T
P
P
V
N
T
V
T
D
A
Q
L
F
S
K
F
T
G
N
V
V
Y
V
----
V
N
S
-
E
N
N
N
K
D
E
V
K
K
G
K
E
L
I
E
A
T
G
A
K
L
L
G
V
V
L
N
R
M
P
K
D
K
S
A
S
Y
Y
A
Y
Y
G
T
D
------
1
PsiBlast_PDB
80.96
44%
-100
- C2 -
3BFV
2
CAP8A_STAAU
A:
[47-256]
---------------------------------
R
S
T
S
S
L
I
V
H
E
Q
P
K
S
P
I
S
E
K
F
R
G
I
R
S
N
I
M
F
A
N
P
D
S
A
V
Q
S
I
V
I
T
S
E
A
P
G
A
G
K
S
T
I
A
A
N
L
A
V
A
Y
A
Q
A
G
Y
K
T
L
I
V
D
G
D
M
R
K
P
T
Q
H
Y
I
F
------
N
L
P
-
N
-
N
--
E
G
L
S
S
L
L
L
N
W
S
T
Y
Q
D
S
I
I
S
T
-
E
I
E
D
L
D
V
L
T
S
G
P
I
P
P
N
P
S
E
L
I
T
S
R
A
F
A
N
L
Y
D
T
L
L
--
M
N
Y
N
F
V
I
I
D
T
P
P
V
N
T
V
T
D
A
Q
L
F
S
K
F
T
G
N
V
V
Y
V
----
V
N
S
-
E
N
N
N
K
D
E
V
K
K
G
K
E
L
I
E
A
T
G
A
K
L
L
G
V
V
L
N
R
M
P
K
-------------------
21
PsiBlast_CBE
79.98
44%
-97
- C2 -
3BFV
2
CAP8A_STAAU
B:
[47-256]
---------------------------------
R
S
T
S
S
L
I
V
H
E
Q
P
K
S
P
I
S
E
K
F
R
G
I
R
S
N
I
M
F
A
N
P
D
S
A
V
Q
S
I
V
I
T
S
E
A
P
G
A
G
K
S
T
I
A
A
N
L
A
V
A
Y
A
Q
A
G
Y
K
T
L
I
V
D
G
D
M
R
K
P
T
Q
H
Y
I
F
------
N
L
P
-
N
-
N
--
E
G
L
S
S
L
L
L
N
W
S
T
Y
Q
D
S
I
I
S
T
-
E
I
E
D
L
D
V
L
T
S
G
P
I
P
P
N
P
S
E
L
I
T
S
R
A
F
A
N
L
Y
D
T
L
L
--
M
N
Y
N
F
V
I
I
D
T
P
P
V
N
T
V
T
D
A
Q
L
F
S
K
F
T
G
N
V
V
Y
V
----
V
N
S
-
E
N
N
N
K
D
E
V
K
K
G
K
E
L
I
E
A
T
G
A
K
L
L
G
V
V
L
N
R
M
P
K
-------------------
3
PsiBlast_PDB
79.45
42%
-88
- C2 -
4JLV
2
?
A:
[57-254]
-------------------------------------------
K
P
K
S
T
I
S
E
K
F
R
G
I
R
S
N
I
M
F
S
K
--
G
E
V
K
R
L
L
V
T
S
E
K
P
G
A
G
K
S
T
V
V
S
N
V
A
I
T
Y
A
Q
A
G
Y
K
T
L
V
I
D
G
D
M
R
K
P
T
Q
N
Y
I
F
------
N
E
Q
-
N
-
N
--
N
G
L
S
S
L
I
I
G
R
T
T
M
S
E
A
I
T
S
T
-
E
I
E
N
L
D
L
L
T
A
G
P
V
P
P
N
P
S
E
L
I
G
S
E
R
F
K
E
L
V
D
L
F
N
--
K
R
Y
D
I
I
I
V
D
T
P
P
V
N
T
V
T
D
A
Q
L
Y
A
R
A
I
K
D
S
L
L
V
----
I
D
N
-
E
K
N
D
K
N
E
V
K
K
A
K
A
L
M
E
K
A
G
S
N
I
L
G
V
I
L
N
K
T
---------------------
129
HHSearch
79.33
41%
-88
- C2 -
4JLV
2
?
A:
[56-254]
------------------------------------------
E
K
P
K
S
T
I
S
E
K
F
R
G
I
R
S
N
I
M
F
S
K
--
G
E
V
K
R
L
L
V
T
S
E
K
P
G
A
G
K
S
T
V
V
S
N
V
A
I
T
Y
A
Q
A
G
Y
K
T
L
V
I
D
G
D
M
R
K
P
T
Q
N
Y
I
F
------
N
E
Q
-
N
-
N
--
N
G
L
S
S
L
I
I
G
R
T
T
M
S
E
A
I
T
S
T
-
E
I
E
N
L
D
L
L
T
A
G
P
V
P
P
N
P
S
E
L
I
G
S
E
R
F
K
E
L
V
D
L
F
N
--
K
R
Y
D
I
I
I
V
D
T
P
P
V
N
T
V
T
D
A
Q
L
Y
A
R
A
I
K
D
S
L
L
V
----
I
D
N
-
E
K
N
D
K
N
E
V
K
K
A
K
A
L
M
E
K
A
G
S
N
I
L
G
V
I
L
N
K
T
---------------------
130
HHSearch
78.99
45%
-101
- C- -
4JMP
-
?
A:
[1015-1215]
------------------------------------------
E
Q
P
K
S
P
I
S
E
K
F
R
G
I
R
S
N
I
M
F
A
-
P
D
S
A
V
Q
S
I
V
I
T
S
E
A
P
G
A
G
K
S
T
I
A
A
N
L
A
V
A
Y
A
Q
A
G
Y
K
T
L
I
V
D
G
D
M
R
K
P
T
Q
H
Y
I
F
------
N
L
P
-
N
-
N
--
E
G
L
S
S
L
L
L
N
W
S
T
Y
Q
D
S
I
I
S
T
-
E
I
E
D
L
D
V
L
T
S
G
P
I
P
P
N
P
S
E
L
I
T
S
R
A
F
A
N
L
Y
D
T
L
L
--
M
N
Y
N
F
V
I
I
D
T
P
P
V
N
T
V
T
D
A
Q
L
F
S
K
F
T
G
N
V
V
Y
V
----
V
N
S
-
E
N
N
N
K
D
E
V
K
K
G
K
E
L
I
E
A
T
G
A
K
L
L
G
V
V
L
N
R
M
P
K
-------------------
131
HHSearch
75.21
36%
-101
- C2 -
3CIO
2
ETK_ECOLI
A:
[77-283]
-----------------------------------------
V
D
N
P
A
D
S
A
V
E
A
V
R
A
L
R
T
S
L
H
F
A
M
M
E
T
E
N
N
I
L
M
I
T
G
A
T
P
D
S
G
K
T
F
V
S
S
T
L
A
A
V
I
A
Q
S
D
Q
K
V
L
F
I
D
A
D
L
R
R
G
Y
S
H
N
L
F
------
T
V
S
-
N
-
E
--
H
G
L
S
E
Y
L
A
G
K
D
E
L
N
K
V
I
Q
H
F
-
G
K
G
G
F
D
V
I
T
R
G
Q
V
P
P
N
P
S
E
L
L
M
R
D
R
M
R
Q
L
L
E
W
A
N
--
D
H
Y
D
L
V
I
V
D
T
P
P
M
L
A
V
S
D
A
A
V
V
G
R
S
V
G
T
S
L
L
V
----
A
R
F
-
G
L
N
T
A
K
E
V
S
L
S
M
Q
R
L
E
Q
A
G
V
N
I
K
G
A
I
L
N
G
V
I
K
R
A
S
-
T
A
-------------
128
HHSearch
71.60
32%
-118
* C2 *
3LA6
2
WZC_ECOLI
A:
[65-270]
-----------------------------------------
V
G
N
P
T
D
L
A
I
E
A
I
R
S
L
R
T
S
L
H
F
A
M
M
Q
A
Q
N
N
V
L
M
M
T
G
V
S
P
S
I
G
M
T
F
V
C
A
N
L
A
A
V
I
S
Q
T
N
K
R
V
L
L
I
D
C
D
M
R
K
G
Y
T
H
E
L
L
------
G
T
N
-
N
-
V
--
N
G
L
S
E
I
L
I
G
Q
G
D
I
T
T
A
A
K
P
T
-
S
I
A
K
F
D
L
I
P
R
G
Q
V
P
P
N
P
S
E
L
L
M
S
E
R
F
A
E
L
V
N
W
A
S
--
K
N
Y
D
L
V
L
I
D
T
P
P
I
L
A
V
T
D
A
A
I
V
G
R
H
V
G
T
T
L
M
V
----
A
R
Y
-
A
V
N
T
L
K
E
V
E
T
S
L
S
R
F
E
Q
N
G
I
P
V
K
G
V
I
L
N
S
I
F
R
R
A
S
-
A
--------------
31
PsiBlast_CBE
68.28
33%
-111
- C2 -
3LA6
2
WZC_ECOLI
D:
[59-277]
-----------------------------------
Q
S
Q
L
L
A
V
G
N
P
T
D
L
A
I
E
A
I
R
S
L
R
T
S
L
H
F
A
M
M
Q
A
Q
N
N
V
L
M
M
T
G
V
S
P
S
I
G
M
T
F
V
C
A
N
L
A
A
V
I
S
Q
T
N
K
R
V
L
L
I
D
C
D
M
R
K
G
Y
T
H
E
L
L
------
G
T
N
-
N
-
V
--
N
G
L
S
E
I
L
I
G
Q
G
D
I
T
T
A
A
K
P
T
-
S
I
A
K
F
D
L
I
P
R
G
Q
V
P
P
N
P
S
E
L
L
M
S
E
R
F
A
E
L
V
N
W
A
S
--
K
N
Y
D
L
V
L
I
D
T
P
P
I
L
A
V
T
D
A
A
I
V
G
R
H
V
G
T
T
L
M
V
ARYA
V
N
T
-
L
K
E
V
E
T
S
L
S
R
F
E
Q
N
G
I
P
V
K
G
V
I
L
N
S
I
F
--
R
R
A
S
A
Y
-
Q
D
Y
G
Y
Y
---------
32
PsiBlast_CBE
67.71
33%
-114
- C2 -
3LA6
2
WZC_ECOLI
C:
[59-277]
-----------------------------------
Q
S
Q
L
L
A
V
G
N
P
T
D
L
A
I
E
A
I
R
S
L
R
T
S
L
H
F
A
M
M
Q
A
Q
N
N
V
L
M
M
T
G
V
S
P
S
I
G
M
T
F
V
C
A
N
L
A
A
V
I
S
Q
T
N
K
R
V
L
L
I
D
C
D
M
R
K
G
Y
T
H
E
L
L
------
G
T
N
-
N
-
V
--
N
G
L
S
E
I
L
I
G
Q
G
D
I
T
T
A
A
K
P
T
-
S
I
A
K
F
D
L
I
P
R
G
Q
V
P
P
N
P
S
E
L
L
M
S
E
R
F
A
E
L
V
N
W
A
S
--
K
N
Y
D
L
V
L
I
D
T
P
P
I
L
A
V
T
D
A
A
I
V
G
R
H
V
G
T
T
L
M
V
A
R
Y
A
V
N
T
-
L
K
E
V
E
T
S
L
S
R
F
E
Q
N
G
I
P
V
K
G
V
I
L
N
S
I
F
--
R
R
A
S
A
Y
-
Q
D
Y
G
Y
Y
---------
33
PsiBlast_CBE
67.31
33%
-114
- C2 -
3LA6
2
WZC_ECOLI
B:
[59-277]
-----------------------------------
Q
S
Q
L
L
A
V
G
N
P
T
D
L
A
I
E
A
I
R
S
L
R
T
S
L
H
F
A
M
M
Q
A
Q
N
N
V
L
M
M
T
G
V
S
P
S
I
G
M
T
F
V
C
A
N
L
A
A
V
I
S
Q
T
N
K
R
V
L
L
I
D
C
D
M
R
K
G
Y
T
H
E
L
L
------
G
T
N
-
N
-
V
--
N
G
L
S
E
I
L
I
G
Q
G
D
I
T
T
A
A
K
P
T
-
S
I
A
K
F
D
L
I
P
R
G
Q
V
P
P
N
P
S
E
L
L
M
S
E
R
F
A
E
L
V
N
W
A
S
--
K
N
Y
D
L
V
L
I
D
T
P
P
I
L
A
V
T
D
A
A
I
V
G
R
H
V
G
T
T
L
M
V
A
R
Y
A
V
N
T
-
L
K
E
V
E
T
S
L
S
R
F
E
Q
N
G
I
P
V
K
G
V
I
L
N
S
I
F
--
R
R
A
S
A
Y
-
Q
D
Y
G
Y
Y
---------
30
PsiBlast_CBE
67.16
33%
-112
- C2 -
3LA6
2
WZC_ECOLI
E:
[59-277]
-----------------------------------
Q
S
Q
L
L
A
V
G
N
P
T
D
L
A
I
E
A
I
R
S
L
R
T
S
L
H
F
A
M
M
Q
A
Q
N
N
V
L
M
M
T
G
V
S
P
S
I
G
M
T
F
V
C
A
N
L
A
A
V
I
S
Q
T
N
K
R
V
L
L
I
D
C
D
M
R
K
G
Y
T
H
E
L
L
------
G
T
N
-
N
-
V
--
N
G
L
S
E
I
L
I
G
Q
G
D
I
T
T
A
A
K
P
T
-
S
I
A
K
F
D
L
I
P
R
G
Q
V
P
P
N
P
S
E
L
L
M
S
E
R
F
A
E
L
V
N
W
A
S
--
K
N
Y
D
L
V
L
I
D
T
P
P
I
L
A
V
T
D
A
A
I
V
G
R
H
V
G
T
T
L
M
V
ARYA
V
N
T
-
L
K
E
V
E
T
S
L
S
R
F
E
Q
N
G
I
P
V
K
G
V
I
L
N
S
I
F
--
R
R
A
S
A
Y
-
Q
D
Y
G
Y
Y
---------
4
PsiBlast_PDB
67.10
33%
-112
- C2 -
3LA6
2
WZC_ECOLI
A:
[59-277]
-----------------------------------
Q
S
Q
L
L
A
V
G
N
P
T
D
L
A
I
E
A
I
R
S
L
R
T
S
L
H
F
A
M
M
Q
A
Q
N
N
V
L
M
M
T
G
V
S
P
S
I
G
M
T
F
V
C
A
N
L
A
A
V
I
S
Q
T
N
K
R
V
L
L
I
D
C
D
M
R
K
G
Y
T
H
E
L
L
------
G
T
N
-
N
-
V
--
N
G
L
S
E
I
L
I
G
Q
G
D
I
T
T
A
A
K
P
T
-
S
I
A
K
F
D
L
I
P
R
G
Q
V
P
P
N
P
S
E
L
L
M
S
E
R
F
A
E
L
V
N
W
A
S
--
K
N
Y
D
L
V
L
I
D
T
P
P
I
L
A
V
T
D
A
A
I
V
G
R
H
V
G
T
T
L
M
V
A
R
Y
A
V
N
T
-
L
K
E
V
E
T
S
L
S
R
F
E
Q
N
G
I
P
V
K
G
V
I
L
N
S
I
F
--
R
R
A
S
A
Y
-
Q
D
Y
G
Y
Y
---------
118
Fugue
65.39
34%
22
- C2 -
3CIO
2
ETK_ECOLI
A:
[25-290]
GVEAPE
Q
L
E
E
H
GISVY
A
T
I
P
M
S
E
W
L
D
K
R
Q
Q
R
H
R
T
K
N
I
P
F
L
A
V
D
N
P
A
D
S
A
V
E
A
V
R
A
L
R
T
S
L
H
F
A
M
M
E
T
E
N
N
I
L
M
I
T
G
A
T
P
D
S
G
K
T
F
V
S
S
T
L
A
A
V
I
A
Q
S
D
Q
K
V
L
F
I
D
A
D
L
R
R
G
Y
S
H
N
L
F
------
T
V
S
-
N
-
E
--
H
G
L
S
E
Y
L
A
G
K
D
E
L
N
K
V
I
Q
H
F
-
G
K
G
G
F
D
V
I
T
R
G
Q
V
P
P
N
P
S
E
L
L
M
R
D
R
M
R
Q
L
L
E
W
A
N
--
D
H
Y
D
L
V
I
V
D
T
P
P
M
L
A
V
S
D
A
A
V
V
G
R
S
V
G
T
S
L
L
V
----
A
R
F
-
G
L
N
T
A
K
E
V
S
L
S
M
Q
R
L
E
Q
A
G
V
N
I
K
G
A
I
L
N
G
V
I
K
R
A
S
-
T
A
Y
S
Y
G
Y
N
Y
------
132
HHSearch
53.00
23%
-32
- C2 -
1G3Q
2
?
A:
[2-176]
--------------------------------------------------------------------
G
R
I
I
S
I
V
S
G
K
G
G
T
G
K
T
T
V
T
A
N
L
S
V
A
L
G
D
R
G
R
K
V
L
A
V
D
G
D
L
T
M
A
N
L
S
L
V
L
------
G
V
D
D
P
-
D
--
V
T
L
H
D
V
L
A
G
E
A
N
V
E
D
A
I
Y
M
T
-
Q
F
D
N
V
Y
V
L
P
G
A
V
D
W
E
H
V
-
L
K
A
D
P
R
K
L
P
E
V
I
K
S
L
K
--
D
K
F
D
F
I
L
I
D
C
P
A
G
L
Q
L
-
D
A
M
S
A
M
L
S
G
E
E
A
L
L
V
----
T
N
P
-
E
I
S
C
L
T
D
T
M
K
V
G
I
V
L
K
K
A
G
L
A
I
L
G
F
V
L
N
R
Y
G
R
S
------------------
8
PsiBlast_PDB
49.88
24%
-72
- C3 -
1ION
2
?
A:
[3-120]
---------------------------------------------------------------------
R
I
I
S
I
V
S
G
K
G
G
T
G
K
T
T
V
T
A
N
L
S
V
A
L
G
E
M
G
R
K
V
L
A
V
D
G
D
L
T
M
A
N
L
S
L
V
L
------
G
V
D
-
D
-
V
N-
I
T
L
H
D
V
L
A
G
D
A
K
L
E
D
A
I
Y
M
T
-
Q
F
E
N
V
Y
I
L
-
P
G
A
V
D
W
E
H
V
I
K
A
D
P
R
K
L
P
E
V
I
K
S
L
K
--
G
K
Y
D
F
I
L
I
D
C
P
--------------------------------------------------------------------------------
20
PsiBlast_PDB
48.74
22%
0
- C- -
5AUN
4
?
B:
[1-197]
-----------------------------------------------
M
N
A
I
D
P
R
E
I
A
I
N
A
R
L
E
G
V
K
R
---
I
I
P
V
V
S
G
K
G
G
V
G
K
S
L
V
S
T
T
L
A
L
V
L
A
E
K
G
Y
R
V
G
L
L
D
L
D
F
H
G
A
S
D
H
V
I
L
GFEPKE
F
P
E
-
E
-
D
--
R
G
V
V
P
P
T
V
H
G
I
K
F
M
T
I
A
Y
Y
T
-
E
D
R
--------
P
T
P
L
R
G
K
E
-
I
S
D
A
L
I
E
L
L
T
I
T
R
W
--
D
E
L
D
Y
L
V
I
D
M
P
P
G
L
G
D
Q
L
L
D
V
L
R
F
L
K
R
G
E
F
L
V
----
V
A
T
P
S
K
L
S
L
N
V
V
R
K
L
I
E
L
L
K
E
E
G
H
K
V
I
G
V
V
E
N
M
K
---------------------
135
HHSearch
48.24
25%
4
- C2 -
4V03
2
?
A:
[2-180]
--------------------------------------------------------------------
A
E
V
I
V
I
T
S
G
K
G
G
V
G
K
T
T
L
T
A
N
I
G
T
A
L
A
K
L
G
K
K
V
L
L
I
D
A
D
---
R
N
L
D
M
I
L
------
G
L
E
-
N
-
R
IV
Y
D
I
L
D
V
L
E
G
R
V
P
Y
E
K
A
L
V
K
D
K
R
G
L
S
L
W
L
L
P
----------
V
I
D
I
E
K
W
N
K
T
V
E
E
I
K
N
S
G
N
Y
D
Y
I
L
V
D
S
P
A
G
I
E
K
-
G
F
Q
I
A
V
S
P
A
D
K
A
L
I
V
----
V
N
P
-
E
V
S
S
I
R
D
A
D
R
V
I
G
L
L
E
S
M
D
K
R
N
Y
K
V
I
V
N
R
I
K
W
E
M
-----------------
138
HHSearch
48.18
22%
-29
- C2 -
1HYQ
-
?
A:
[2-176]
--------------------------------------------------------------------
V
R
T
I
T
V
A
S
G
K
G
G
T
G
K
T
T
I
T
A
N
L
G
V
A
L
A
Q
L
G
H
D
V
T
I
V
D
A
D
I
T
M
A
N
L
E
L
I
L
------
G
M
E
-
G
L
P
--
V
T
L
Q
N
V
L
A
G
E
A
R
I
D
E
A
I
Y
-
V
-
G
P
G
G
V
K
V
V
P
A
G
V
S
L
E
G
L
-
R
K
A
N
P
E
K
L
E
D
V
L
T
Q
I
M
--
E
S
T
D
I
L
L
L
D
A
P
A
G
L
E
R
-
S
A
V
I
A
I
A
A
A
Q
E
L
L
L
V
----
V
N
P
-
E
I
S
S
I
T
D
G
L
K
T
K
I
V
A
E
R
L
G
T
K
V
L
G
V
V
V
N
R
I
T
T
L
G
-----------------