@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu37090: (2016-08-01 )
MERSLSMELVRVTEAAALASARWMGRGKKDEADEAATSAMRDVFDTVPMKGTVVIGEGEMDEAPMLYIGEKLGNGYGPRVDVAVDPLEGTNILASGGWNALTVIAVADHGTLLNAPDMYMQKIAVGPEAVGCIDIEAPVIDNLKAVAKAKNKDVEDVVATILNRERHAKIISELREAGARIKLINDGDVAGAINTAFDHTGVDILFGSGGAPEGVLSAVALKALGGEIIGKLLPQSEEEITRCHKMGLDLSKVLRMEDLVKGDDAIFAATGVTDGELLKGVQFKGSVGTTESLVIRAKSGTVRFVDGRHSLKKKPNLVIRP
Atome Classification :
(20 SA)
---------.........10........20........30........40........-------50........60........70..--------...------------..------------.80........90.....-...100.......110-------------........120...----....130.......140.......150.......160---.......170.......180.......190.......200.......210.......220.......230.--..-------------.------------.------------..240.......-.-250.......260.......270....-...280.......290...---....300.......310.......320------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------MERSLS
M
E
L
V
R
V
T
E
A
A
A
L
A
S
A
R
WMGRGKKD
E
A
D
E
A
A
T
S
A
M
R
D
V
F
DTVPM-------K
G
T
V
V
I
GEGEMDEA
P
M
L
Y
I
G
E
K
LG--------NGY------------GP------------R
V
D
V
A
VDPLEG
T
N
I
L
ASG-GW
N
A
L
T
V
I
A
V
ADHGT--------------LLN
A
P
D
M
Y
M
Q
K
IAV----GPE
A
V
G
C
I
D
IEA
P
V
I
D
N
L
K
A
V
A
KAKNK
D
V
E
D
V
V
A
T
I
L---N
R
E
R
H
A
K
I
I
S
E
L
R
EAG
A
R
I
K
L
I
NDGDVAGAINTAFDHTG
V
D
I
L
FGSGGA
P
E
G
V
L
S
A
V
A
L
K
A
L
G
G
E
I
I
G
K
LL--PQ-------------
S
------------
E
------------
E
E
I
T
-
R
C
H
KMGL-
D
-
L
S
K
V
L
R
M
E
D
L
VKGDD
A
I
F
A
ATGVT
D
G
E
-
L
L
KG
V
Q
FKGSVGTT
E
S
L
V
I
---
R
AKSG
T
V
R
F
VDG
R
H
SLKKKP
N
L
V
IRP-------------------------------
95
HHSearch
81.99
50%
-67
- C4 -
3BIG
2
GLPX_ECOLI
A:
[3-326]
---------
M
R
R
E
L
A
I
E
F
S
R
V
T
E
S
A
A
L
A
G
Y
K
W
L
G
R
G
D
K
N
T
A
D
G
A
A
V
N
A
M
R
I
M
L
N
Q
V
N
I
-------
D
G
T
I
V
I
G
E
G
E
I
A
E
A
P
M
L
Y
I
G
E
K
V
G
--------
T
G
R
------------
G
D
------------
A
V
D
I
A
V
D
P
I
E
G
T
R
M
T
A
M
G
-
Q
A
N
A
L
A
V
L
A
V
G
D
K
G
C
--------------
F
L
N
A
P
D
M
Y
M
E
K
L
I
V
----
G
P
G
A
K
G
T
I
D
L
N
L
P
L
A
D
N
L
R
N
V
A
A
A
L
G
K
P
L
S
E
L
T
V
T
I
L
---
A
K
P
R
H
D
A
V
I
A
E
M
Q
Q
L
G
V
R
V
F
A
I
P
D
G
D
V
A
A
S
I
L
T
C
M
P
D
S
E
V
D
V
L
Y
G
I
G
G
A
P
E
G
V
V
S
A
A
V
I
R
A
L
D
G
D
M
N
G
R
L
L
--
A
R
-------------
H
------------
D
VKN
E
E
N
R
R
I
G
E
-
Q
E
L
A
-
R
C
K
A
M
G
I
-
E
-
A
G
K
V
L
R
L
G
D
M
A
R
S
D
N
V
I
F
S
A
T
G
I
T
K
G
D
-
L
L
E
G
I
S
R
K
G
N
I
A
T
T
E
T
L
L
I
---
R
G
K
S
-
T
I
R
R
I
Q
S
I
H
Y
L
-----------------------------------------
4
PsiBlast_PDB
81.71
49%
-67
- C4 -
3BIG
2
GLPX_ECOLI
A:
[3-326]
---------
M
R
R
E
L
A
I
E
F
S
R
V
T
E
S
A
A
L
A
G
Y
K
W
L
G
R
G
D
K
N
T
A
D
G
A
A
V
N
A
M
R
I
M
L
N
Q
V
N
I
-------
D
G
T
I
V
I
G
E
G
E
I
A
E
A
P
M
L
Y
I
G
E
K
V
G
--------
T
G
R
------------
G
D
------------
A
V
D
I
A
V
D
P
I
E
G
T
R
M
T
A
M
G
-
Q
A
N
A
L
A
V
L
A
V
G
D
K
G
C
--------------
F
L
N
A
P
D
M
Y
M
E
K
L
I
V
----
G
P
G
A
K
G
T
I
D
L
N
L
P
L
A
D
N
L
R
N
V
A
A
A
L
G
K
P
L
S
E
L
T
V
T
I
L
---
A
K
P
R
H
D
A
V
I
A
E
M
Q
Q
L
G
V
R
V
F
A
I
P
D
G
D
V
A
A
S
I
L
T
C
M
P
D
S
E
V
D
V
L
Y
G
I
G
G
A
P
E
G
V
V
S
A
A
V
I
R
A
L
D
G
D
M
N
G
R
L
L
--
A
R
-------------
H
DVKN
E
E
N
R
R
I
G
-
E
------------
Q
E
L
A
-
R
C
K
A
M
G
I
-
E
-
A
G
K
V
L
R
L
G
D
M
A
R
S
D
N
V
I
F
S
A
T
G
I
T
K
G
D
-
L
L
E
G
I
S
R
K
G
N
I
A
T
T
E
T
L
L
I
---
R
G
K
S
-
T
I
R
R
I
Q
S
I
H
Y
L
-----------------------------------------
2
PsiBlast_PDB
81.42
49%
-67
- C4 -
3D1R
5
GLPX_ECOLI
A:
[2-324]
---------
M
R
R
E
L
A
I
E
F
S
R
V
T
E
S
A
A
L
A
G
Y
K
W
L
G
R
G
D
K
N
T
A
D
G
A
A
V
N
A
M
R
I
M
L
N
Q
V
N
I
-------
D
G
T
I
V
I
G
E
G
E
I
A
E
A
P
M
L
Y
I
G
E
K
V
G
--------
T
G
R
------------
G
D
------------
A
V
D
I
A
V
D
P
I
E
G
T
R
M
T
A
M
G
-
Q
A
N
A
L
A
V
L
A
V
G
D
K
G
C
--------------
F
L
N
A
P
D
M
Y
M
E
K
L
I
V
----
G
P
G
A
K
G
T
I
D
L
N
L
P
L
A
D
N
L
R
N
V
A
A
A
L
G
K
P
L
S
E
L
T
V
T
I
L
---
A
K
P
R
H
D
A
V
I
A
E
M
Q
Q
L
G
V
R
V
F
A
I
P
D
G
D
V
A
A
S
I
L
T
C
M
P
D
S
E
V
D
V
L
Y
G
I
G
G
A
P
E
G
V
V
S
A
A
V
I
R
A
L
D
G
D
M
N
G
R
L
L
--
A
R
-------------
H
DVKGDNE
N
R
R
I
G
E
------------
Q
E
L
A
-
R
C
K
A
M
G
I
-
E
-
A
G
K
V
L
R
L
G
D
M
A
R
S
D
N
V
I
F
S
A
T
G
I
T
K
G
D
-
L
L
E
G
I
S
R
K
G
N
I
A
T
T
E
T
L
L
I
---
R
G
K
S
-
T
I
R
R
I
Q
S
I
H
Y
------------------------------------------
5
PsiBlast_PDB
81.14
49%
-62
- C4 -
3BIH
1
GLPX_ECOLI
A:
[3-326]
---------
M
R
R
E
L
A
I
E
F
S
R
V
T
E
S
A
A
L
A
G
Y
K
W
L
G
R
G
D
K
N
T
A
D
G
A
A
V
N
A
M
R
I
M
L
N
Q
V
N
I
-------
D
G
T
I
V
I
G
E
G
E
I
A
E
A
P
M
L
Y
I
G
E
K
V
G
--------
T
G
R
------------
G
D
------------
A
V
D
I
A
V
D
P
I
E
G
T
R
M
T
A
M
G
-
Q
A
N
A
L
A
V
L
A
V
G
D
K
G
C
--------------
F
L
N
A
P
D
M
Y
M
E
K
L
I
V
----
G
P
G
A
K
G
T
I
D
L
N
L
P
L
A
D
N
L
R
N
V
A
A
A
L
G
K
P
L
S
E
L
T
V
T
I
L
---
A
K
P
R
H
D
A
V
I
A
E
M
Q
Q
L
G
V
R
V
F
A
I
P
D
G
D
V
A
A
S
I
L
T
C
M
P
D
S
E
V
D
V
L
Y
G
I
G
G
A
P
E
G
V
V
S
A
A
V
I
R
A
L
D
G
D
M
N
G
R
L
L
--
A
R
-------------
H
DVKN
E
E
N
R
R
I
G
-
E
------------
Q
E
L
A
-
R
C
K
A
M
G
I
-
E
-
A
G
K
V
L
R
L
G
D
M
A
R
S
D
N
V
I
F
S
A
T
G
I
T
K
G
D
-
L
L
E
G
I
S
R
K
G
N
I
A
T
T
E
T
L
L
I
---
R
G
K
S
R
T
I
R
R
I
Q
S
I
H
Y
L
-----------------------------------------
3
PsiBlast_PDB
80.06
49%
-58
- C4 -
2R8T
4
GLPX_ECOLI
A:
[4-326]
----------
R
R
E
L
A
I
E
F
S
R
V
T
E
S
A
A
L
A
G
Y
K
W
L
G
R
G
D
K
N
T
A
D
G
A
A
V
N
A
M
R
I
M
L
N
Q
V
N
I
-------
D
G
T
I
V
I
G
E
G
E
I
A
E
A
P
M
L
Y
I
G
E
K
V
G
--------
T
G
R
------------
G
D
------------
A
V
D
I
A
V
D
P
I
E
G
T
R
M
T
A
M
G
-
Q
A
N
A
L
A
V
L
A
V
G
D
K
G
C
--------------
F
L
N
A
P
D
M
Y
M
E
K
L
I
V
----
G
P
G
A
K
G
T
I
D
L
N
L
P
L
A
D
N
L
R
N
V
A
A
A
L
G
K
P
L
S
E
L
T
V
T
I
L
---
A
K
P
R
H
D
A
V
I
A
E
M
Q
Q
L
G
V
R
V
F
A
I
P
D
G
D
V
A
A
S
I
L
T
C
M
P
D
S
E
V
D
V
L
Y
G
I
G
G
A
P
E
G
V
V
S
A
A
V
I
R
A
L
D
G
D
M
N
G
R
L
L
--
A
R
-------------
H
DVKE
N
R
R
I
G
---
E
------------
Q
E
L
A
-
R
C
K
A
M
G
I
-
E
-
A
G
K
V
L
R
L
G
D
M
A
R
S
D
N
V
I
F
S
A
T
G
I
T
K
G
D
-
L
L
E
G
I
S
R
K
G
N
I
A
T
T
E
T
L
L
I
---
R
G
K
S
R
T
I
R
R
I
Q
S
I
H
Y
L
-----------------------------------------
1
PsiBlast_PDB
78.87
49%
-95
- C4 -
1NI9
2
GLPX_ECOLI
A:
[3-328]
---------
M
R
R
E
L
A
I
E
F
S
R
V
T
E
S
A
A
L
A
G
Y
K
W
L
G
R
G
D
K
N
T
A
D
G
A
A
V
N
A
M
R
I
M
L
N
Q
V
N
I
-------
D
G
T
I
V
I
G
E
G
---
E
A
P
M
L
Y
I
G
E
K
V
G
--------
T
G
R
------------
G
D
------------
A
V
D
I
A
V
D
P
I
E
G
T
-------
Q
A
N
A
L
A
V
L
A
V
G
D
K
G
C
--------------
F
L
N
A
P
D
M
Y
M
E
K
L
I
V
----
G
P
G
A
K
G
T
I
D
L
N
L
P
L
A
D
N
L
R
N
V
A
A
A
L
G
K
P
L
S
E
L
T
V
T
I
L
---
A
K
--
H
D
A
V
I
A
E
M
Q
Q
L
G
V
R
V
F
A
I
P
D
G
D
V
A
A
S
I
L
T
C
M
P
D
S
E
V
D
V
L
Y
G
I
G
G
A
P
E
G
V
V
S
A
A
V
I
R
A
L
D
G
D
M
N
G
R
L
L
--
A
--------------------------------------------------
G
I
-
E
-
A
G
K
V
L
R
L
G
D
M
A
R
S
D
N
V
I
F
S
A
T
G
I
T
K
G
D
-
L
L
E
G
I
S
R
K
G
N
I
A
T
T
E
T
L
L
I
---
R
G
K
S
R
T
I
R
R
I
Q
S
I
H
Y
L
D
R
---------------------------------------
22
PsiBlast_CBE
76.86
41%
-19
- C4 -
3RPL
13
FBSB_SYNY3
C:
[35-376]
---------
V
D
S
T
L
G
L
E
I
I
E
V
V
E
Q
A
A
I
A
S
A
K
W
M
G
K
G
E
K
N
T
A
D
Q
V
A
V
E
A
M
R
E
R
M
N
K
I
H
M
-------
R
G
R
I
V
I
G
E
G
E
R
D
D
A
P
M
L
Y
I
G
E
E
V
G
ICTREDAK
S
F
C
------------
N
P
DELV--------
E
I
D
I
A
V
D
P
C
E
G
T
N
L
V
A
Y
G
-
Q
N
G
S
M
A
V
L
A
I
S
E
K
G
G
--------------
L
F
A
A
P
D
F
Y
M
K
K
L
A
A
----
P
P
A
A
K
G
H
V
D
I
D
K
S
A
T
E
N
L
K
I
L
S
D
C
L
N
R
S
I
E
E
L
V
V
V
V
M
---
D
R
P
R
H
K
E
L
I
Q
E
I
R
N
A
G
A
R
V
R
L
I
S
D
G
D
V
S
A
A
I
S
C
A
F
S
G
T
N
I
H
A
L
M
G
I
G
A
A
P
E
G
V
I
S
A
A
A
M
R
C
L
G
G
H
F
Q
G
Q
L
I
YD
P
E
VVKTGLIGES---
R
------------
E
------------
G
N
L
E
-
R
L
A
S
M
G
I
K
N
-
P
D
Q
V
Y
N
C
E
E
L
A
C
G
E
T
V
L
F
A
A
C
G
I
T
P
G
T
-
L
M
E
G
V
R
F
F
H
G
G
V
R
T
Q
S
L
V
I
---
S
S
Q
S
S
T
A
R
F
V
D
T
V
H
-
M
K
E
S
P
K
V
I
----------------------------------
23
PsiBlast_CBE
76.80
41%
-19
- C4 -
3RPL
11
FBSB_SYNY3
A:
[35-376]
---------
V
D
S
T
L
G
L
E
I
I
E
V
V
E
Q
A
A
I
A
S
A
K
W
M
G
K
G
E
K
N
T
A
D
Q
V
A
V
E
A
M
R
E
R
M
N
K
I
H
M
-------
R
G
R
I
V
I
G
E
G
E
R
D
D
A
P
M
L
Y
I
G
E
E
V
G
ICTREDAK
S
F
C
------------
N
P
DELV--------
E
I
D
I
A
V
D
P
C
E
G
T
N
L
V
A
Y
G
-
Q
N
G
S
M
A
V
L
A
I
S
E
K
G
G
--------------
L
F
A
A
P
D
F
Y
M
K
K
L
A
A
----
P
P
A
A
K
G
H
V
D
I
D
K
S
A
T
E
N
L
K
I
L
S
D
C
L
N
R
S
I
E
E
L
V
V
V
V
M
---
D
R
P
R
H
K
E
L
I
Q
E
I
R
N
A
G
A
R
V
R
L
I
S
D
G
D
V
S
A
A
I
S
C
A
F
S
G
T
N
I
H
A
L
M
G
I
G
A
A
P
E
G
V
I
S
A
A
A
M
R
C
L
G
G
H
F
Q
G
Q
L
I
YD
P
E
VVKTGLIGES---
R
------------
E
------------
G
N
L
E
-
R
L
A
S
M
G
I
K
N
-
P
D
Q
V
Y
N
C
E
E
L
A
C
G
E
T
V
L
F
A
A
C
G
I
T
P
G
T
-
L
M
E
G
V
R
F
F
H
G
G
V
R
T
Q
S
L
V
I
---
S
S
Q
S
S
T
A
R
F
V
D
T
V
H
-
M
K
E
S
P
K
V
I
----------------------------------
21
PsiBlast_CBE
76.57
41%
-19
- C4 -
3RPL
9
FBSB_SYNY3
D:
[35-376]
---------
V
D
S
T
L
G
L
E
I
I
E
V
V
E
Q
A
A
I
A
S
A
K
W
M
G
K
G
E
K
N
T
A
D
Q
V
A
V
E
A
M
R
E
R
M
N
K
I
H
M
-------
R
G
R
I
V
I
G
E
G
E
R
D
D
A
P
M
L
Y
I
G
E
E
V
G
ICTREDAK
S
F
C
------------
N
P
DELV--------
E
I
D
I
A
V
D
P
C
E
G
T
N
L
V
A
Y
G
-
Q
N
G
S
M
A
V
L
A
I
S
E
K
G
G
--------------
L
F
A
A
P
D
F
Y
M
K
K
L
A
A
----
P
P
A
A
K
G
H
V
D
I
D
K
S
A
T
E
N
L
K
I
L
S
D
C
L
N
R
S
I
E
E
L
V
V
V
V
M
---
D
R
P
R
H
K
E
L
I
Q
E
I
R
N
A
G
A
R
V
R
L
I
S
D
G
D
V
S
A
A
I
S
C
A
F
S
G
T
N
I
H
A
L
M
G
I
G
A
A
P
E
G
V
I
S
A
A
A
M
R
C
L
G
G
H
F
Q
G
Q
L
I
YD
P
E
VVKTGLIGES---
R
------------
E
------------
G
N
L
E
-
R
L
A
S
M
G
I
K
N
-
P
D
Q
V
Y
N
C
E
E
L
A
C
G
E
T
V
L
F
A
A
C
G
I
T
P
G
T
-
L
M
E
G
V
R
F
F
H
G
G
V
R
T
Q
S
L
V
I
---
S
S
Q
S
S
T
A
R
F
V
D
T
V
H
-
M
K
E
S
P
K
V
I
----------------------------------
7
PsiBlast_PDB
76.57
41%
-19
- C4 -
3RPL
10
FBSB_SYNY3
B:
[35-376]
---------
V
D
S
T
L
G
L
E
I
I
E
V
V
E
Q
A
A
I
A
S
A
K
W
M
G
K
G
E
K
N
T
A
D
Q
V
A
V
E
A
M
R
E
R
M
N
K
I
H
M
-------
R
G
R
I
V
I
G
E
G
E
R
D
D
A
P
M
L
Y
I
G
E
E
V
G
ICTREDAK
S
F
C
------------
N
P
DELV--------
E
I
D
I
A
V
D
P
C
E
G
T
N
L
V
A
Y
G
-
Q
N
G
S
M
A
V
L
A
I
S
E
K
G
G
--------------
L
F
A
A
P
D
F
Y
M
K
K
L
A
A
----
P
P
A
A
K
G
H
V
D
I
D
K
S
A
T
E
N
L
K
I
L
S
D
C
L
N
R
S
I
E
E
L
V
V
V
V
M
---
D
R
P
R
H
K
E
L
I
Q
E
I
R
N
A
G
A
R
V
R
L
I
S
D
G
D
V
S
A
A
I
S
C
A
F
S
G
T
N
I
H
A
L
M
G
I
G
A
A
P
E
G
V
I
S
A
A
A
M
R
C
L
G
G
H
F
Q
G
Q
L
I
YD
P
E
VVKTGLIGES---
R
------------
E
------------
G
N
L
E
-
R
L
A
S
M
G
I
K
N
-
P
D
Q
V
Y
N
C
E
E
L
A
C
G
E
T
V
L
F
A
A
C
G
I
T
P
G
T
-
L
M
E
G
V
R
F
F
H
G
G
V
R
T
Q
S
L
V
I
---
S
S
Q
S
S
T
A
R
F
V
D
T
V
H
-
M
K
E
S
P
K
V
I
----------------------------------
8
PsiBlast_PDB
76.53
41%
-11
- C4 -
5A5L
4
FBSB_THEEB
A:
[18-354]
---------
M
D
N
V
I
G
L
E
I
I
E
V
V
E
Q
A
A
I
A
S
A
R
W
M
G
K
G
D
K
N
M
A
D
Q
A
A
V
D
A
M
R
N
R
M
N
Q
I
H
M
-------
R
G
R
I
V
I
G
E
G
E
R
D
E
A
P
M
L
Y
I
G
E
E
V
G
--------
I
C
T
------------
R
P
DAAQYCNPEEL
I
E
I
D
I
A
V
D
P
C
E
G
T
N
L
C
A
Y
G
-
Q
P
G
S
M
A
V
L
A
I
S
E
K
G
G
--------------
L
F
A
A
P
D
F
Y
M
K
K
L
A
A
----
P
P
A
A
K
G
K
V
D
I
R
N
S
A
T
E
N
L
K
I
L
S
E
C
L
D
R
A
I
D
E
L
V
V
V
V
M
---
K
R
D
R
H
N
D
L
I
Q
E
I
R
D
A
G
A
R
V
Q
L
I
S
D
G
D
V
S
A
A
L
A
C
A
F
S
G
T
N
I
H
A
L
M
G
I
G
A
A
P
E
G
V
I
S
A
A
A
M
R
A
L
G
G
H
F
Q
G
Q
L
V
--
Y
D
PAVVMTKEWANRT
R
------------
E
------------
G
N
L
E
-
E
L
K
K
A
G
I
T
D
-
P
D
K
V
Y
E
A
E
E
L
A
S
G
E
T
V
L
F
A
A
C
G
I
T
P
G
M
-
L
M
K
G
V
R
F
F
K
G
G
A
R
T
Q
S
L
V
I
---
S
T
Q
S
K
T
A
R
F
V
D
T
I
H
M
F
-----------------------------------------
6
PsiBlast_PDB
76.53
41%
-21
- C4 -
3ROJ
21
FBSB_SYNY3
A:
[35-376]
---------
V
D
S
T
L
G
L
E
I
I
E
V
V
E
Q
A
A
I
A
S
A
K
W
M
G
K
G
E
K
N
T
A
D
Q
V
A
V
E
A
M
R
E
R
M
N
K
I
H
M
-------
R
G
R
I
V
I
G
E
G
E
R
D
D
A
P
M
L
Y
I
G
E
E
V
G
ICTREDAK
S
F
C
------------
N
P
DELV--------
E
I
D
I
A
V
D
P
C
E
G
T
N
L
V
A
Y
G
-
Q
N
G
S
M
A
V
L
A
I
S
E
K
G
G
--------------
L
F
A
A
P
D
F
Y
M
K
K
L
A
A
----
P
P
A
A
K
G
H
V
D
I
D
K
S
A
T
E
N
L
K
I
L
S
D
C
L
N
R
S
I
E
E
L
V
V
V
V
M
---
D
R
P
R
H
K
E
L
I
Q
E
I
R
N
A
G
A
R
V
R
L
I
S
D
G
D
V
S
A
A
I
S
C
A
F
S
G
T
N
I
H
A
L
M
G
I
G
A
A
P
E
G
V
I
S
A
A
A
M
R
C
L
G
G
H
F
Q
G
Q
L
I
YD
P
E
VVKTGLIGES---
R
------------
E
------------
G
N
L
E
-
R
L
A
S
M
G
I
K
N
-
P
D
Q
V
Y
N
C
E
E
L
A
C
G
E
T
V
L
F
A
A
C
G
I
T
P
G
T
-
L
M
E
G
V
R
F
F
H
G
G
V
R
T
Q
S
L
V
I
---
S
S
Q
S
S
T
A
R
F
V
D
T
V
H
-
M
K
E
S
P
K
V
I
----------------------------------
94
HHSearch
75.78
43%
-22
- C4 -
3ROJ
21
FBSB_SYNY3
A:
[36-379]
----------
D
S
T
L
G
L
E
I
I
E
V
V
E
Q
A
A
I
A
S
A
K
W
M
G
K
G
E
K
N
T
A
D
Q
V
A
V
E
A
M
R
E
R
M
N
K
I
H
M
-------
R
G
R
I
V
I
G
E
G
E
R
D
D
A
P
M
L
Y
I
G
E
E
V
G
--------
I
C
T
REDAKSFCNPDE
L
V
------------
E
I
D
I
A
V
D
P
C
E
G
T
N
L
V
A
Y
G
-
Q
N
G
S
M
A
V
L
A
I
S
E
K
G
G
--------------
L
F
A
A
P
D
F
Y
M
K
K
L
A
A
----
P
P
A
A
K
G
H
V
D
I
D
K
S
A
T
E
N
L
K
I
L
S
D
C
L
N
R
S
I
E
E
L
V
V
V
V
M
---
D
R
P
R
H
K
E
L
I
Q
E
I
R
N
A
G
A
R
V
R
L
I
S
D
G
D
V
S
A
A
I
S
C
A
F
S
G
T
N
I
H
A
L
M
G
I
G
A
A
P
E
G
V
I
S
A
A
A
M
R
C
L
G
G
H
F
Q
G
Q
L
I
--
Y
D
-------------
P
------------
E
VVKTGLIGES
R
E
G
N
L
E
-
R
L
A
S
M
G
I
-
K
N
P
D
Q
V
Y
N
C
E
E
L
A
C
G
E
T
V
L
F
A
A
C
G
I
T
P
G
T
-
L
M
E
G
V
R
F
F
H
G
G
V
R
T
Q
S
L
V
I
---
S
S
Q
S
S
T
A
R
F
V
D
T
V
H
M
K
E
S
P
K
V
I
Q
L
H
--------------------------------
84
Fugue
70.54
52%
9
- C4 -
1NI9
2
GLPX_ECOLI
A:
[1-327]
-------GH
M
R
R
E
L
A
I
E
F
S
R
V
T
E
S
A
A
L
A
G
Y
K
W
L
G
R
G
D
K
N
T
A
D
G
A
A
V
N
A
M
R
I
M
L
N
Q
V
N
I
-------
D
G
T
I
V
I
G
E
G
E
---
A
P
M
L
Y
I
G
E
K
V
G
--------
T
G
R
------------
G
D
------------
A
V
D
I
A
V
D
P
I
E
G
T
Q
A
-------
N
A
L
A
V
L
A
V
G
D
K
G
C
--------------
F
L
N
A
P
D
M
Y
M
E
K
L
I
V
----
G
P
G
A
K
G
T
I
D
L
N
L
P
L
A
D
N
L
R
N
V
A
A
A
L
G
K
P
L
S
E
L
T
V
T
I
L
-----
A
K
H
D
A
V
I
A
E
M
Q
Q
L
G
V
R
V
F
A
I
P
D
G
D
V
A
A
S
I
L
T
C
M
P
D
S
E
V
D
V
L
Y
G
I
G
G
A
P
E
G
V
V
S
A
A
V
I
R
A
L
D
G
D
M
N
G
R
L
L
--
A
G
-------------
I
--------------------------------------
E
-
A
G
K
V
L
R
L
G
D
M
A
R
S
D
N
V
I
F
S
A
T
G
I
T
K
G
D
-
L
L
E
G
I
S
R
K
G
N
I
A
T
T
E
T
L
L
I
---
R
G
K
S
R
T
I
R
R
I
Q
S
I
H
Y
L
D
----------------------------------------
93
Fugue
34.05
12%
-87
- C4 -
1JW9
4
MOEB_ECOLI
B:
[2-248]
------------------
A
E
L
S
D
Q
E
M
L
R
Y
N
R
Q
I
---
I
L
R
G
F
D
F
D
G
Q
E
A
L
K
D
S
--------------
R
V
L
I
V
G
L
G
G
L
G
C
A
A
S
Q
Y
L
A
S
A
-------------------------------------------------------------
G
V
G
N
L
T
L
L
D
F
D
T
--------------
V
-
S
L
S
N
L
Q
R
Q
T
L
H
S
----
D
A
T
------
V
G
Q
P
K
V
E
S
A
R
D
A
L
T
R
I
N
P
H
I
--
A
I
T
P
V
N
---
A
L
L
D
D
A
E
L
A
A
L
I
A
E
H
D
L
V
L
D
C
T
D
N
V
A
V
R
N
Q
L
N
A
G
C
F
A
A
K
V
P
L
V
S
G
A
A
I
R
M
E
G
Q
I
T
V
F
T
Y
Q
D
G
E
P
C
Y
R
C
L
S
R
--
L
F
-------------
G
------------
E
------------
A
G
V
M
------------------------
A
P
L
I
G
V
I
G
S
L
Q
A
M
E
-
A
I
K
M
L
A
G
Y
G
K
P
A
S
G
K
I
V
M
Y
---
D
A
M
T
C
Q
F
R
E
M
K
----
L
M
R
N
P
G
C
E
V
C
G
-------------------------------
98
HHSearch
33.78
23%
-94
- C4 -
1VDW
1
?
A:
[45-110]
---------------------------------------
V
V
D
K
V
A
E
N
I
I
I
S
K
F
K
D
-
L
---------
G
V
N
V
V
S
E
E
I
G
R
I
D
-------------------
Q
-------------
G
S
------------
D
Y
T
V
V
V
D
P
L
D
G
S
Y
N
F
I
N
G
-
I
P
F
F
A
V
S
V
A
I
F
H
E
K
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
58
PsiBlast_CBE
31.62
32%
-132
- C5 -
2WJW
1
GRIA2_HUMAN
A:
[196-265]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
Q
V
I
T
I
G
K
H
V
K
G
Y
H
Y
I
I
A
N
L
G
F
T
D
G
D
-
L
L
K
-
I
Q
F
G
G
A
N
V
S
G
F
Q
I
V
D
---
Y
D
D
S
L
V
S
K
F
I
E
R
W
S
T
L
E
E
K
--------------------------------------
104
HHSearch
31.58
26%
-89
- C4 -
4N81
1
?
A:
[44-112]
--------------------------------------
T
K
A
D
R
G
A
E
Q
A
M
R
A
I
L
E
Q
E
R
P
--------
E
D
G
I
F
G
E
----
S
R
-------------------
P
-------------
D
A
------------
R
R
L
W
V
L
D
P
I
D
G
T
R
A
F
I
G
G
-
R
A
S
F
G
T
L
I
A
L
V
E
D
G
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
101
HHSearch
31.47
19%
-95
- C4 -
2PCR
-
BSUHB_AQUAE
A:
[44-112]
--------------------------------------
S
Y
V
D
K
T
S
E
E
R
I
K
E
V
I
L
K
F
F
--------
P
D
H
E
V
V
G
E
----------------------------------------
S
------------
E
Y
R
W
F
I
D
P
L
D
G
T
K
N
Y
I
N
G
-
F
P
I
F
A
V
S
V
G
L
V
K
G
E
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
85
Fugue
31.17
16%
-48
- C4 -
4KPP
4
?
A:
[2-396]
DF
T
K
E
K
F
Q
L
L
A
I
S
S
L
T
L
P
W
L
I
S
L
A
F
N
Y
H
H
P
A
L
T
Q
T
L
L
S
G
L
A
V
V
S
A
S
F
L
I
S
W
A
A
E
T
A
E
M
D
VPRSFS
L
A
I
V
A
L
L
A
V
L
P
E
Y
A
V
D
G
Y
F
A
W
K
A
G
--------
S
V
G
------------
G
E
------------
Y
V
H
Y
A
T
A
N
M
T
G
A
N
R
L
L
I
G
I
G
W
S
L
V
A
F
I
A
F
R
T
L
K
S
K
E
V
E
L
D
DGI
R
L
E
I
F
F
L
F
L
A
T
L
Y
A
F
T
L
P
L
K
GHI
S
P
F
D
A
L
V
F
V
S
L
Y
A
I
Y
I
Y
L
S
T
K
A
E
R
E
E
V
E
V
G
G
V
P
A
Y
L
C
S
LK
T
E
T
R
R
L
S
V
V
V
L
F
L
F
A
G
F
T
I
L
M
S
V
E
A
F
S
E
G
L
L
E
T
A
R
I
A
G
I
D
E
F
L
A
V
Q
W
I
A
P
L
A
S
E
S
P
E
L
I
V
A
I
Y
F
V
R
R
F
R
V
S
--
A
S
-------------
M
------------
N
------------
A
L
I
S
S
K
V
N
Q
W
T
L
-
L
-
I
G
T
I
A
I
I
Y
S
I
S
A
F
K
L
Q
S
L
P
L
D
A
R
Q
S
E
E
V
L
L
T
A
A
Q
S
L
F
A
V
A
I
L
L
D
L
K
I
S
W
K
E
A
S
A
L
F
L
L
F
I
V
Q
L
L
F
P
G
V
E
V
R
Y
I
I
S
A
I
Y
I
I
L
S
L
P
I
L
F
A
K
R
K
E
I
V
E
S
F
R
T
V
K
R
L
I
S
LE