@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu40870: (2016-08-08 )
MANIKEIARLANVSVSTVSRVLNHHPYVSEEKRKLVHQVMKELDYTPNRTAIDLIRGKTHTVGVILPYSDHPCFDKIVNGITKAAFQHEYATTLLPTNYNPDIEIKYLELLRTKKIDGLIITSRANHWDSILAYQEYGPVIACEDTGDIDVPCAFNDRKTAYAESFRYLKSRGHENIAFTCVREADRSPSTADKAAAYKAVCGRLEDRHMLSGCNDMNDGELAAEHFYMSGRVPTAIYANSDEVAAGIHLFAKKNNWDVEIIGEGNTSISRVLGFPSLDLNLEQLGIAAFSLFLQDEPADIKIQHKFKKKA
Atome Classification :
(21 SA)
.........10........20......-..30........40........50........60........70........80........90........100.......110.......120.......130..--....--.---140--...------..-...-150.......160.......170.......180....---...190.......200--...----.....210--.---.-......220.......230.......240.......250.....----..260.......270.--......280.......290..------.....300.......310
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MA
N
I
K
E
I
A
R
L
AN
V
S
V
S
T
V
S
R
V
L
NHHPY-V
S
E
E
K
R
K
L
V
H
Q
V
M
K
ELDYTPNR
T
A
I
D
L
IRGKT
H
T
V
G
V
I
L
PYSDHP
C
F
D
K
I
V
N
G
I
T
K
A
A
F
Q
H
EYA
T
T
LLPTNYNPD
I
E
I
K
Y
L
E
L
L
R
TKKID
G
L
I
I
TSRANH
W
D
S
I
L
A
Y
--
Q
EYG--
P
---
V
I
---
A
CE------DT-GDI-DVPCAFNDR
K
T
A
Y
A
E
S
F
R
Y
L
K
SRGHE
N
I
A
F
T
C
VREAD---RSPST
A
D
K
A
A
A
Y
K
A
V
---
C
GR----LE
D
R
H
M
L---S---G-CNDMND
G
E
L
A
A
E
H
F
YMSGRV
P
T
A
I
Y
ANS
D
E
V
A
A
G
I
H
L
F
A
KKNNW----
D
V
E
I
I
GEGNT
S
I
S
R
VL--GFPSLDL
N
L
E
Q
L
G
I
A
A
F
S
L
FL------QDEPA
D
I
K
I
Q
H
K
FKKKA
20
PsiBlast_PDB
73.49
26%
-47
- C3 -
1JH9
4
PURR_ECOLI
A:
[1-327]
-
A
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
-
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
-
S
E
Y
P
E
P
L
L
A
M
L
-
E
E
Y
R
H
I
P
---
M
V
---
V
M
D
RGEAKA
D
F
-
T
D
A
-
V
I
D
N
A
F
E
G
G
Y
M
A
----
G
R
Y
L
I
E
R
G
H
R
E
I
G
-
V
I
P
G
P
L
E
---
R
N
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
----
V
P
E
S
W
I
V
---
Q
---
G
-
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
RVPQ
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
TP
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
VNK
R
E
E
P
Q
S
I
E
V
H
P
R
L
I
E
R
-
17
PsiBlast_PDB
72.86
26%
-55
- C3 -
1QPZ
2
PURR_ECOLI
A:
[1-327]
-
A
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
-
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
-
S
E
Y
P
E
P
L
L
A
M
L
-
E
E
Y
R
HI
P
---
M
V
---
V
M
D
WGEAKA
D
F
-
T
D
A
-
V
I
D
N
A
F
E
G
G
Y
M
A
----
G
R
Y
L
I
E
R
G
H
R
E
I
G
-
V
I
P
G
P
L
E
---
R
N
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
----
V
P
E
S
W
I
V
---
Q
---
G
-
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
RVPQ
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
TP
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
V
NK
R
E
E
P
Q
S
I
E
V
H
P
R
L
I
E
R
-
12
PsiBlast_PDB
72.42
26%
-47
- C3 -
1PNR
2
PURR_ECOLI
A:
[2-327]
--
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
-
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
-
S
E
Y
P
E
P
L
L
A
M
L
-
E
E
Y
R
HI
P
---
M
V
---
V
M
D
WGEAKA
D
F
-
T
D
A
-
V
I
D
N
A
F
E
G
G
Y
M
A
----
G
R
Y
L
I
E
R
G
H
R
E
I
G
-
V
I
P
G
P
L
E
---
R
N
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
----
V
P
E
S
W
I
V
---
Q
---
G
-
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
RVPQ
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
TP
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
VNK
R
E
E
P
Q
S
I
E
V
H
P
R
L
I
E
R
-
18
PsiBlast_PDB
72.33
26%
-47
- C3 -
1ZAY
2
PURR_ECOLI
A:
[2-327]
--
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
-
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
-
S
E
Y
P
E
P
L
L
A
M
L
-
E
E
Y
R
HI
P
---
M
V
---
V
M
D
WGEAKA
D
F
-
T
D
A
-
V
I
D
N
A
F
E
G
G
Y
M
A
----
G
R
Y
L
I
E
R
G
H
R
E
I
G
-
V
I
P
G
P
L
E
---
R
N
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
----
V
P
E
S
W
I
V
---
Q
---
G
-
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
RVPQ
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
TP
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
VNK
R
E
E
P
Q
S
I
E
V
H
P
R
L
I
E
R
-
14
PsiBlast_PDB
72.24
26%
-46
- C3 -
1WET
2
PURR_ECOLI
A:
[2-327]
--
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
-
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
-
S
E
Y
P
E
P
L
L
A
M
L
-
E
E
Y
R
HI
P
---
M
V
---
V
M
D
WGEAKA
D
F
-
T
D
A
-
V
I
D
N
A
F
E
G
G
Y
M
A
----
G
R
Y
L
I
E
R
G
H
R
E
I
G
-
V
I
P
G
P
L
E
---
R
N
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
----
V
P
E
S
W
I
V
---
Q
---
G
-
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
RVPQ
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
TP
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
V
NK
R
E
E
P
Q
S
I
E
V
H
P
R
L
I
E
R
-
15
PsiBlast_PDB
71.94
26%
-47
- C3 -
1QP0
2
PURR_ECOLI
A:
[2-327]
--
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
-
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
-
S
E
Y
P
E
P
L
L
A
M
L
-
E
E
Y
R
HI
P
---
M
V
---
V
M
D
WGEAKA
D
F
-
T
D
A
-
V
I
D
N
A
F
E
G
G
Y
M
A
----
G
R
Y
L
I
E
R
G
H
R
E
I
G
-
V
I
P
G
P
L
E
---
R
N
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
----
V
P
E
S
W
I
V
---
Q
---
G
-
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
RVPQ
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
TP
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
VNK
R
E
E
P
Q
S
I
E
V
H
P
R
L
I
E
R
-
7
PsiBlast_PDB
71.59
26%
-41
* C3 *
1JFT
3
PURR_ECOLI
A:
[1-327]
-
A
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
-
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
-
S
E
Y
P
E
P
L
L
A
M
L
-
E
E
Y
R
HI
P
---
M
V
V
MD
A
G
E
------
A
K
-
A
D
F
-
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
-
R
Y
L
I
E
R
G
H
R
E
I
G
-
V
I
P
G
P
L
E
---
R
N
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
----
V
P
E
S
W
I
V
---
Q
---
G
-
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
RVPQ
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
TP
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
V
NK
R
E
E
P
Q
S
I
E
V
H
P
R
L
I
E
R
-
13
PsiBlast_PDB
71.52
26%
-46
- C3 -
1BDI
2
PURR_ECOLI
A:
[2-327]
--
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
-
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
-
S
E
Y
P
E
P
L
L
A
M
L
-
E
E
Y
R
HI
P
---
M
V
---
V
M
D
WGEAKA
D
F
-
T
D
A
-
V
I
D
N
A
F
E
G
G
Y
M
A
----
G
R
Y
L
I
E
R
G
H
R
E
I
G
-
V
I
P
G
P
L
E
---
R
N
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
----
V
P
E
S
W
I
V
---
Q
---
G
-
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
RVPQ
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
TP
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
VNK
R
E
E
P
Q
S
I
E
V
H
P
R
L
I
E
R
-
69
HHSearch
71.23
24%
-65
- C3 -
1QPZ
2
PURR_ECOLI
A:
[1-309]
-
A
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
-
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
E
Y
R
H
I
--
P
---
M
V
---
V
M
D
------
W
G
E
A
K
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
-----
R
N
T
G
A
G
R
L
A
G
F
M
K
A
---
M
E
E
----
A
M
I
K
V
P
E
SW
I
V
---
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
RVPQ
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
TP
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
------
D
R
I
V
-------------
19
PsiBlast_PDB
71.16
26%
-48
- C3 -
1JFS
2
PURR_ECOLI
A:
[1-327]
-
A
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
-
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
-
S
E
Y
P
E
P
L
L
A
M
L
-
E
E
Y
R
HI
P
---
M
V
---
V
M
D
FGEAKA
D
F
-
T
D
A
-
V
I
D
N
A
F
E
G
G
Y
M
A
----
G
R
Y
L
I
E
R
G
H
R
E
I
G
-
V
I
P
G
P
L
E
---
R
N
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
----
V
P
E
S
W
I
V
---
Q
---
G
-
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
RVPQ
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
TP
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
VNK
R
E
E
P
Q
S
I
E
V
H
P
R
L
I
E
R
-
16
PsiBlast_PDB
71.10
26%
-51
- C3 -
1QP4
2
PURR_ECOLI
A:
[2-327]
--
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
-
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
-
S
E
Y
P
E
P
L
L
A
M
L
-
E
E
Y
R
HI
P
---
M
V
---
V
M
D
WGEAKA
D
F
-
T
D
A
-
V
I
D
N
A
F
E
G
G
Y
M
A
----
G
R
Y
L
I
E
R
G
H
R
E
I
G
-
V
I
P
G
P
L
E
---
R
N
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
----
V
P
E
S
W
I
V
---
Q
---
G
-
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
RVPQ
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
TP
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
VNK
R
E
E
P
Q
S
I
E
V
H
P
R
L
I
E
R
-
8
PsiBlast_PDB
70.63
26%
-50
- C3 -
1BDH
2
PURR_ECOLI
A:
[2-327]
--
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
-
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
A
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
-
S
E
Y
P
E
P
L
L
A
M
L
-
E
E
Y
R
HI
P
---
M
V
---
V
M
D
WGEAKA
D
F
-
T
D
A
-
V
I
D
N
A
F
E
G
G
Y
M
A
----
G
R
Y
L
I
E
R
G
H
R
E
I
G
-
V
I
P
G
P
L
E
---
R
N
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
----
V
P
E
S
W
I
V
---
Q
---
G
-
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
RVPQ
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
TP
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
VNK
R
E
E
P
Q
S
I
E
V
H
P
R
L
I
E
R
-
9
PsiBlast_PDB
70.46
26%
-48
- C3 -
1QP7
2
PURR_ECOLI
A:
[2-327]
--
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
-
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
A
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
-
S
E
Y
P
E
P
L
L
A
M
L
-
E
E
Y
R
HI
P
---
M
V
---
V
M
D
WGEAKA
D
F
-
T
D
A
-
V
I
D
N
A
F
E
G
G
Y
M
A
----
G
R
Y
L
I
E
R
G
H
R
E
I
G
-
V
I
P
G
P
L
E
---
R
N
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
----
V
P
E
S
W
I
V
---
Q
---
G
-
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
RVPQ
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
TP
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
VNK
R
E
E
P
Q
S
I
E
V
H
P
R
L
I
E
R
-
10
PsiBlast_PDB
70.41
26%
-46
- C3 -
1QQA
2
PURR_ECOLI
A:
[2-327]
--
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
-
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
A
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
-
S
E
Y
P
E
P
L
L
A
M
L
-
E
E
Y
R
HI
P
---
M
V
---
V
M
D
WGEAKA
D
F
-
T
D
A
-
V
I
D
N
A
F
E
G
G
Y
M
A
----
G
R
Y
L
I
E
R
G
H
R
E
I
G
-
V
I
P
G
P
L
E
---
R
N
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
----
V
P
E
S
W
I
V
---
Q
---
G
-
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
RVPQ
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
TP
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
VNK
R
E
E
P
Q
S
I
E
V
H
P
R
L
I
E
R
-
11
PsiBlast_PDB
70.02
26%
-48
- C3 -
1QQB
2
PURR_ECOLI
A:
[2-327]
--
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
-
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
A
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
-
S
E
Y
P
E
P
L
L
A
M
L
-
E
E
Y
R
HI
P
---
M
V
---
V
M
D
WGEAKA
D
F
-
T
D
A
-
V
I
D
N
A
F
E
G
G
Y
M
A
----
G
R
Y
L
I
E
R
G
H
R
E
I
G
-
V
I
P
G
P
L
E
---
R
N
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
----
V
P
E
S
W
I
V
---
Q
---
G
-
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
RVPQ
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
TP
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
VNK
R
E
E
P
Q
S
I
E
V
H
P
R
L
I
E
R
-
3
PsiBlast_PDB
68.59
29%
-39
- C3 -
3OQM
4
CCPA_BACSU
A:
[5-280]
---
I
Y
D
V
A
R
E
A
N
V
S
M
A
T
V
S
R
V
V
N
G
N
P
N
-
V
K
P
T
T
R
K
K
V
L
E
A
I
E
R
L
G
Y
R
P
N
A
V
A
R
G
L
A
S
K
K
T
T
T
V
G
V
I
I
P
D
I
S
S
I
F
Y
S
E
L
A
R
G
I
E
D
I
A
T
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
M
E
K
E
L
H
L
L
N
T
M
L
G
K
Q
V
D
G
I
V
F
M
G
-
G
N
I
T
D
E
H
V
A
E
--
F
K
R
S
--
P
V
P
I
V
L
---
A
A
S
------
V
E
-
E
Q
E
-
E
T
P
S
V
A
I
D
Y
E
Q
A
I
Y
D
A
V
K
L
L
V
D
K
G
H
T
D
I
A
F
V
S
G
P
M
A
E
PIN
R
S
K
K
L
Q
G
Y
K
R
A
L
E
E
A
---
N
L
P
----
F
N
E
Q
F
V
A
---
E
---
G
-
D
Y
T
Y
D
S
G
L
E
A
L
Q
H
L
M
S
L
D
K
K
P
T
A
I
L
S
A
T
D
E
M
A
L
G
I
I
H
A
A
Q
D
Q
G
L
SIPE
D
L
D
I
I
G
F
D
N
T
R
L
S
-------------------------------------------------
2
PsiBlast_PDB
68.26
29%
-44
- C3 -
1ZVV
4
CCPA_BACSU
A:
[5-283]
---
I
Y
D
V
A
R
E
A
S
V
S
M
A
T
V
S
R
V
V
N
G
N
P
N
-
V
K
P
S
T
R
K
K
V
L
E
T
I
E
R
L
G
Y
R
P
N
A
V
A
R
G
L
A
S
K
K
T
T
T
V
G
V
I
I
P
D
I
S
N
I
F
Y
A
E
L
A
R
G
I
E
D
I
A
S
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
Q
D
K
Q
L
H
L
L
N
N
M
L
G
K
Q
V
D
G
I
I
F
M
S
-
G
N
V
T
E
E
H
V
E
E
--
L
K
K
S
--
P
V
P
V
V
L
---
A
A
S
------
I
E
-
S
T
N
-
Q
I
P
S
V
T
I
D
Y
E
Q
A
A
F
D
A
V
Q
S
L
I
D
S
G
H
K
N
I
A
F
V
S
-
G
T
L
E
---
E
P
I
N
H
A
K
K
V
K
G
Y
K
R
A
---
L
T
E
S
G
L
P
V
R
D
S
Y
I
V
---
E
---
G
-
D
Y
T
Y
D
S
G
I
E
A
V
E
K
L
L
E
E
D
E
K
P
T
A
I
F
V
G
T
D
E
M
A
L
G
V
I
H
G
A
Q
D
R
G
L
NVPN
D
L
E
I
I
G
F
D
N
T
R
L
S
T
M
V
----------------------------------------------
5
PsiBlast_PDB
68.15
29%
-45
- C3 -
3OQO
4
CCPA_BACSU
A:
[5-280]
---
I
Y
D
V
A
R
E
A
N
V
S
M
A
T
V
S
R
V
V
N
G
N
P
N
-
V
K
P
T
T
R
K
K
V
L
E
A
I
E
R
L
G
Y
R
P
N
A
V
A
R
G
L
A
S
K
K
T
T
T
V
G
V
I
I
P
D
I
S
S
I
F
Y
S
E
L
A
R
G
I
E
D
I
A
T
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
M
E
K
E
L
H
L
L
N
T
M
L
G
K
Q
V
D
G
I
V
F
M
G
-
G
N
I
T
D
E
H
V
A
E
--
F
K
R
S
--
P
V
P
I
V
L
---
A
A
S
------
V
E
-
E
Q
E
-
E
T
P
S
V
A
I
D
Y
E
Q
A
I
Y
D
A
V
K
L
L
V
D
K
G
H
T
D
I
A
F
V
S
G
P
M
A
E
PIN
R
S
K
K
L
Q
G
Y
K
R
A
L
E
E
A
---
N
L
P
----
F
N
E
Q
F
V
A
---
E
---
G
-
D
Y
T
Y
D
S
G
L
E
A
L
Q
H
L
M
S
L
D
K
K
P
T
A
I
L
S
A
T
D
E
M
A
L
G
I
I
H
A
A
Q
D
Q
G
L
SIPE
D
L
D
I
I
G
F
D
N
T
R
L
S
-------------------------------------------------
64
HHSearch
67.57
29%
-31
- C3 -
2HSG
-
CCPA_BACME
A:
[2-310]
N
V
T
I
Y
D
V
A
R
E
A
S
V
S
M
A
T
V
S
R
V
V
N
G
N
P
N
-
V
K
P
S
T
R
K
K
V
L
E
T
I
E
R
L
G
Y
R
P
N
A
V
A
R
G
L
A
S
-
K
T
T
T
V
G
V
I
I
P
--
S
N
I
F
Y
A
E
L
A
R
G
I
E
D
I
A
T
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
Q
D
K
E
L
H
L
L
N
N
M
L
G
K
Q
V
D
G
I
I
F
M
S
G
N
V
T
E
E
H
V
E
E
L
K
-
K
S
P
V
--
P
---
V
V
---
L
A
A
------
S
I
E
S
T
N
-
Q
I
P
S
V
T
I
D
Y
E
Q
A
A
F
D
A
V
Q
S
L
I
D
S
G
H
K
N
I
A
F
V
S
G
T
L
E
E
----
P
I
N
H
A
K
K
V
K
G
Y
K
R
A
---
L
T
E
----
S
G
L
P
V
R
D
S--
Y
I
V
E
G
-
D
Y
T
Y
D
S
G
I
E
A
V
E
K
L
L
E
E
D
E
K
P
T
A
I
F
V
G
T
D
E
M
A
L
G
V
I
H
G
A
Q
D
R
G
L
NVPN
D
L
E
I
I
G
F
D
N
T
R
L
S
T
M
V
RP
Q
L
T
S
V
V
Q
P
M
Y
D
I
G
A
V
A
M
R
L
L
T
------
K
Y
M
N
-------------
4
PsiBlast_PDB
66.73
29%
-44
- C3 -
3OQN
2
CCPA_BACSU
A:
[5-280]
---
I
Y
D
V
A
R
E
A
N
V
S
M
A
T
V
S
R
V
V
N
G
N
P
N
-
V
K
P
T
T
R
K
K
V
L
E
A
I
E
R
L
G
Y
R
P
N
A
V
A
R
G
L
A
S
K
K
T
T
T
V
G
V
I
I
P
D
I
S
S
I
F
Y
S
E
L
A
R
G
I
E
D
I
A
T
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
M
E
K
E
L
H
L
L
N
T
M
L
G
K
Q
V
D
G
I
V
F
M
G
-
G
N
I
T
D
E
H
V
A
E
--
F
K
R
S
--
P
V
P
I
V
L
---
A
A
S
------
V
E
-
E
Q
E
-
E
T
P
S
V
A
I
D
Y
E
Q
A
I
Y
D
A
V
K
L
L
V
D
K
G
H
T
D
I
A
F
V
S
G
P
M
A
E
PIN
R
S
K
K
L
Q
G
Y
K
R
A
L
E
E
A
---
N
L
P
----
F
N
E
Q
F
V
A
---
E
---
G
-
D
Y
T
Y
D
S
G
L
E
A
L
Q
H
L
M
S
L
D
K
K
P
T
A
I
L
S
A
T
D
E
M
A
L
G
I
I
H
A
A
Q
D
Q
G
L
SIPE
D
L
D
I
I
G
F
D
N
T
R
L
S
-------------------------------------------------
54
Fugue
30.90
42%
-57
- C3 -
1QPZ
1
PURR_ECOLI
A:
[1-57]
-
A
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
-
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
--
P
S
A
V
A
R
S
L
K
V
N
H
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------