@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv0203: (2016-04-20 )
MKTGTATTRRRLLAVLIALALPGAAVALLAEPSATGASDPCAASEVARTVGSVAKSMGDYLDSHPETNQVMTAVLQQQVGPGSVASLKAHFEANPKVASDLHALSQPLTDLSTRCSLPISGLQAIGLMQAVQGARR
Atome Classification :
(20 SA)
---------------------------------------.........10........20....-----....30........40---------........50........60........70----........80........90........100.....--..110.......120.......130....-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------------------MKTG
T
A
T
T
R
R
R
L
L
A
V
L
I
A
L
ALPG
A
A
-----
V
A
L
L
AEPSATGASDP
C
---------
A
A
S
E
V
A
R
T
V
G
S
V
A
K
S
M
G
D
Y
L
DSHPE
T
N
Q
V
M
----
T
A
V
L
Q
QQVGPG
S
V
A
S
L
K
AHFEANP
K
V
A
S
D
L
H
A
L
SQ
P
--
L
T
D
L
S
T
RCSL
P
I
S
G
L
Q
A
I
G
L
M
Q
A
V
Q
GARR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
88.30
100%
-80
- C2 -
3MAY
-
RV203_MYCTU
A:
[40-125]
------------------------------------------------------------------------------------
C
---------
A
A
S
E
V
A
R
T
V
G
S
V
A
K
S
M
G
D
Y
L
D
S
H
P
E
T
N
Q
V
M
----
T
A
V
L
Q
Q
Q
V
G
P
G
S
V
A
S
L
K
A
H
F
E
A
N
P
K
V
A
S
D
L
H
A
L
S
Q
P
--
L
T
D
L
S
T
R
C
S
L
P
I
S
G
L
Q
A
I
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
88.30
100%
-80
- C2 -
3MAY
-
RV203_MYCTU
A:
[40-125]
------------------------------------------------------------------------------------
C
---------
A
A
S
E
V
A
R
T
V
G
S
V
A
K
S
M
G
D
Y
L
D
S
H
P
E
T
N
Q
V
M
----
T
A
V
L
Q
Q
Q
V
G
P
G
S
V
A
S
L
K
A
H
F
E
A
N
P
K
V
A
S
D
L
H
A
L
S
Q
P
--
L
T
D
L
S
T
R
C
S
L
P
I
S
G
L
Q
A
I
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
88.30
100%
-80
- C2 -
3MAY
-
RV203_MYCTU
A:
[40-125]
------------------------------------------------------------------------------------
C
---------
A
A
S
E
V
A
R
T
V
G
S
V
A
K
S
M
G
D
Y
L
D
S
H
P
E
T
N
Q
V
M
----
T
A
V
L
Q
Q
Q
V
G
P
G
S
V
A
S
L
K
A
H
F
E
A
N
P
K
V
A
S
D
L
H
A
L
S
Q
P
--
L
T
D
L
S
T
R
C
S
L
P
I
S
G
L
Q
A
I
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
53.60
15%
-81
* C3 *
3NBX
2
RAVA_ECOLI
X:
[5-499]
------------------------HPHLLAERISRLSSS
L
E
K
G
-
L
Y
E
R
S
H
A
I
R
L
C
L
L
A
A
L
S
G
E
S
-----
V
F
L
L
G
P
P
---
G
I
A
K
S
L
---------
I
A
R
R
L
K
F
A
F
Q
N
-
A
R
A
F
E
Y
L
M
T
R
F
S
T
P
E
E
V
F
GPLS
E
R
L
T
S
G
Y
L
P
E
A
E
I
V
F
L
D
E
I
W
K
A
G
P
A
I
L
N
T
L
L
T
A
I
N
E
RQ
F
R
N
G
A
H
V
E
K
I
P
M
R
L
L
V
A
A
S
N
E
L
P
E
A
D
S
S
L
EALYDRMLIRLWLDKVQDKANFRSMLTSQQDENDNPVPDALQVTDEEYERWQKEIGEITLPDHVFELIFMLRQQLDKLPDAPYVSDRRWKKAIRLLQASAFFSGRSAVAPVDLILLKDCLWYDAQSLNLIQQQIDVLMTGHAWQQQGMLTRLGAIVQRHLQLQQQQSDKTALTVIRLGGIFSRRQQYQLPVNVTASTLTLLLQKPLKLHDMEVVHISFERSALEQWLSKGGEIRGKLNGIGFAQKLNLEVDSAQHLVVRDVSLQGSTLALPGSLPGEIKQQLEELESDWRKQHALFSEQQKCLFIPGDWLGRIEASLQDVGAQIRQAQQ
37
Fugue
52.39
11%
-93
- C3 -
1YGT
1
DYLT_DROME
A:
[8-111]
----------------------------------------
S
Q
F
I
V
D
D
V
S
K
T
I
K
E
A
I
E
T
T
I
G
G
N
-------------
A
Y
Q
H
D
K
V
N
N
---------
W
T
G
Q
V
V
E
N
C
L
T
V
L
T
K
E
Q
------
K
P
Y
K
Y
I
V
----
T
A
M
I
M
Q
K
N
G
A
G
L
H
T
A
S
S
C
Y
W
N
N
D
T
----------------
D
G
S
C
T
V
R
W
E
N
K
T
M
Y
C
I
V
S
V
F
G
L
A
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
48.66
32%
-44
- C2 -
1AUP
-
DHE2_CLOSY
A:
[7-87]
-----------------------------------------------------------------------
V
I
A
E
V
E
K
K
Y
A
D
E
P
-------------
E
F
V
Q
T
V
E
E
V
L
S
S
L
G
P
V
V
D
A
H
P
E
Y
E
E
V
------
A
L
L
E
R
M
V
I
P
E
R
V
I
E
F
R
V
P
W
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
47.67
32%
-41
- C2 -
1BGV
-
DHE2_CLOSY
A:
[7-65]
-----------------------------------------------------------------------
V
I
A
E
V
E
K
K
Y
A
D
E
P
-------------
E
F
V
Q
T
V
E
E
V
L
S
S
L
G
P
V
V
D
A
H
P
E
Y
E
E
V
------
A
L
L
E
R
M
V
I
P
E
R
V
I
E
F
R
V
P
W
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
47.61
31%
-41
- C2 -
4B56
4
ENPP1_MOUSE
A:
[238-301]
------------------------------------------
G
S
V
P
F
E
E
R
I
L
A
V
L
E
W
L
Q
L
P
S
H
E
RPH
F
Y
T
L
Y
L
E
E
P
D
S
S
G
H
S
H
G
P
---------
V
S
S
E
V
I
K
A
L
Q
K
V
D
R
L
V
G
M
L
M
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_CBE
47.25
31%
-43
- C2 -
4B56
4
ENPP1_MOUSE
B:
[238-301]
------------------------------------------
G
S
V
P
F
E
E
R
I
L
A
V
L
E
W
L
Q
L
P
S
H
E
RPH
F
Y
T
L
Y
L
E
E
P
D
S
S
G
H
S
H
G
P
---------
V
S
S
E
V
I
K
A
L
Q
K
V
D
R
L
V
G
M
L
M
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
47.13
32%
-36
- C2 -
1HRD
-
DHE2_CLOSY
A:
[7-65]
-----------------------------------------------------------------------
V
I
A
E
V
E
K
K
Y
A
D
E
P
-------------
E
F
V
Q
T
V
E
E
V
L
S
S
L
G
P
V
V
D
A
H
P
E
Y
E
E
V
------
A
L
L
E
R
M
V
I
P
E
R
V
I
E
F
R
V
P
W
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
46.74
32%
-42
- C2 -
2YFH
-
DHE2_CLOSY (first)
A:
[8-70]
-----------------------------------------------------------------------
V
I
A
E
V
E
K
K
Y
A
D
E
P
-------------
E
F
V
Q
T
V
E
E
V
L
S
S
L
G
P
V
V
D
A
H
P
E
Y
E
E
V
------
A
L
L
E
R
M
V
I
P
E
R
V
I
E
F
R
V
P
W
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
46.12
32%
-42
- C2 -
1K89
-
DHE2_CLOSY
A:
[7-65]
-----------------------------------------------------------------------
V
I
A
E
V
E
K
K
Y
A
D
E
P
-------------
E
F
V
Q
T
V
E
E
V
L
S
S
L
G
P
V
V
D
A
H
P
E
Y
E
E
V
------
A
L
L
E
R
M
V
I
P
E
R
V
I
E
F
R
V
P
W
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_CBE
45.86
31%
-38
- C2 -
4GTX
4
ENPP1_MOUSE
B:
[242-341]
------------------------------------------
G
S
V
P
F
E
E
R
I
L
A
V
L
E
W
L
Q
L
P
S
H
E
RPH
F
Y
T
L
Y
L
E
E
P
D
S
S
G
H
S
H
G
P
---------
V
S
S
E
V
I
K
A
L
Q
K
V
D
R
L
V
G
M
L
M
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_CBE
45.71
31%
-37
- C2 -
4GTZ
4
ENPP1_MOUSE
B:
[242-341]
------------------------------------------
G
S
V
P
F
E
E
R
I
L
A
V
L
E
W
L
Q
L
P
S
H
E
RPH
F
Y
T
L
Y
L
E
E
P
D
S
S
G
H
S
H
G
P
---------
V
S
S
E
V
I
K
A
L
Q
K
V
D
R
L
V
G
M
L
M
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
45.06
31%
-38
- C2 -
4GTY
4
ENPP1_MOUSE (first)
A:
[242-332]
------------------------------------------
G
S
V
P
F
E
E
R
I
L
A
V
L
E
W
L
Q
L
P
S
H
E
RPH
F
Y
T
L
Y
L
E
E
P
D
S
S
G
H
S
H
G
P
---------
V
S
S
E
V
I
K
A
L
Q
K
V
D
R
L
V
G
M
L
M
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
44.90
31%
-39
- C2 -
4GTZ
4
ENPP1_MOUSE (first)
A:
[242-332]
------------------------------------------
G
S
V
P
F
E
E
R
I
L
A
V
L
E
W
L
Q
L
P
S
H
E
RPH
F
Y
T
L
Y
L
E
E
P
D
S
S
G
H
S
H
G
P
---------
V
S
S
E
V
I
K
A
L
Q
K
V
D
R
L
V
G
M
L
M
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
44.82
31%
-35
- C2 -
4GTW
4
ENPP1_MOUSE (first)
A:
[242-332]
------------------------------------------
G
S
V
P
F
E
E
R
I
L
A
V
L
E
W
L
Q
L
P
S
H
E
RPH
F
Y
T
L
Y
L
E
E
P
D
S
S
G
H
S
H
G
P
---------
V
S
S
E
V
I
K
A
L
Q
K
V
D
R
L
V
G
M
L
M
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_CBE
44.46
31%
-35
- C2 -
4GTY
4
ENPP1_MOUSE
B:
[242-341]
------------------------------------------
G
S
V
P
F
E
E
R
I
L
A
V
L
E
W
L
Q
L
P
S
H
E
RPH
F
Y
T
L
Y
L
E
E
P
D
S
S
G
H
S
H
G
P
---------
V
S
S
E
V
I
K
A
L
Q
K
V
D
R
L
V
G
M
L
M
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
44.22
31%
-32
- C2 -
4GTX
4
ENPP1_MOUSE (first)
A:
[242-332]
------------------------------------------
G
S
V
P
F
E
E
R
I
L
A
V
L
E
W
L
Q
L
P
S
H
E
RPH
F
Y
T
L
Y
L
E
E
P
D
S
S
G
H
S
H
G
P
---------
V
S
S
E
V
I
K
A
L
Q
K
V
D
R
L
V
G
M
L
M
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
44.03
14%
-63
- C3 -
2TS1
-
?
?:
[1-227]
M
D
L
L
A
E
L
Q
W
R
GLVNQTTD
E
D
G
L
R
K
L
L
N
E
ER
V
T
L
Y
C
G
F
D
P
T
A
D
S
L
H
I
G
H
L
A
T
I
L
T
M
R
R
F
Q
Q
A
G
H
R
-----
P
I
A
L
V
G
G
A
T
G
L
I
G
D
P
S
GKK
S
E
R
T
L
N
A
K
E
T
V
E
A
W
S
A
R
I
K
E
Q
L
G
R
F
L
D
F
E
A
D
G
N
P
A
K
----
I
K
N
N
Y
D
W
I
G
P
L
D
V
I
T
F
L
R
D
V
G
K
H
F
S
V
N
Y
M
M
-----
A
--
K
E
S
V
Q
S
R
I
E
T
G
I
S
F
T
E
F
S
Y
M
M
L
Q
A
Y
D
F
L
R
L
Y
E
TEGCR
L
Q
I
G
G
SDQ
W
G
N
I
T
A
G
L
E
L
I
R
K
T
KGR
A
F
G
L
T
I
P
LVTKAD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------