@TOME V2.3
(Nov 2016)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv0204c: (2016-04-20 )
MSHDAPARNLRQRVGALPRTRVGAPPAEGVPPRGKYWWLRWAVLAIVAIVLAIEVALGWDQLAKAWVSLYRAKWWWLLAAVAAAGASMHSFAQIQRTLLKSAGVHVKQWRSEAAFYAANSLSTTLPGGPVLSATFLLRQQRIWGASTVVASWQLVMSGVLQAVGLALLGLGGAFFLGAKNNPFSLLFTLGGFVTLLLLAQAVASRPELIEGIGRRVLSWANSVRGRPADAGLPKWRETLMQLESVSLGRRDLGVAFGWSLFNWIADVACLGFAAYAAGDHASVGGLAVAYAAARAVGTIPLMPGGVLVVEAVLVPGLVSSGMPLPSAISAMLIYRLISWLLIAAIGWVVFFFMFRTESTADSDNDRDPPTDPNLRLVIQPQGTPCDDPVETTPQGPAPTPDLRPEGGETPPR
Atome Classification :
(15 SA)
.........10........20........30........40........50........60........70........80.......----.90........100.......110.......120.....-----..130.......140...-....----.150.......160.......---170.......180.......190.......200....-----------------...210.......220......-.230....---...-240.....---------..250.......260.......270-----.........280....--...290--...--------.....300.--......310.......320.......330----.......340.......350.......360.......370--------------........380.......390.......400.......410----------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MSHD
A
P
A
R
N
L
R
Q
R
VGALPRTRVGAPPAEGVPPRGK
Y
W
W
L
R
W
A
V
L
A
I
V
A
I
V
L
A
I
E
V
AL
G
W
D
Q
L
A
K
A
W
V
S
L
Y
R
A
K
W
W
W
L
L
A
A
V
A
AAGA
S
M
----
H
S
F
A
Q
I
Q
R
T
L
L
K
S
AG
V
H
V
K
Q
W
R
S
E
A
A
F
Y
AANSLSTTLPG-----G
P
V
L
S
A
T
F
L
L
R
Q
Q
-RIWG-A
S
T
V
----
V
A
S
W
Q
L
V
M
S
G
V
L
Q
A
V
G
L
A
L
L
G---LG
G
A
F
F
LGAKNN
P
F
S
L
L
F
T
L
G
G
F
V
T
L
L
L
L
A
Q
A
V
AS
R
P
-----------------
E
L
I
E
G
I
G
R
R
V
L
S
W
A
N
SVRGRPA-DAG
L
P
K
W
R
---
E
T
L
-
M
Q
L
E
S
VSL---------GR
R
D
L
G
V
A
F
G
W
S
L
F
N
W
I
A
D
V
A
C
L
-------
G
F
A
A
YAAGDHASV
G
G
L
--
A
V
A
Y
A
---
A
A
R
--------AVGTIPLMP--G
G
V
L
V
V
E
A
V
LV
P
G
L
V
SSGMP
L
P
S
A
I
S
A
M
L
----
I
Y
R
L
I
S
W
L
L
I
A
A
I
G
W
V
V
F
F
F
MFRTESTADSDNDRDPPTD---------------P
N
L
R
L
V
I
QPQGTPCDDPVETTPQGPAPTPDLRPEGGETPPR----------------------
9
Fugue
87.40
19%
-86
- C8 -
5AEX
2
MEP2_YEAST
A:
[2-457]
-----------------
S
Y
N
F
T
G
T
P
T
G
E
G
T
G
G
N
S
----------------
L
T
T
D
L
N
T
Q
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L
A
N
M
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A
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A
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V
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I
M
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P
G
I
G
L
L
Y
S
G
L
SRKK
H
A
L
-
S
L
L
W
A
S
M
M
A
S
A
V
C
I
F
Q
W
F
F
W
G
Y
S
L
A
F
S
H
--
N
T
R
G
N
-----
G
F
I
G
T
L
E
F
F
-
G
F
R
-
N
V
L
G
-
A
P
S
S
----
V
S
S
L
P
D
I
L
F
A
V
Y
Q
G
M
F
A
A
V
T
G
A
L
M
L
G
G
A
C
E
-
R
A
R
L
F
P
M
M
V
F
L
F
L
W
M
T
I
V
Y
C
P
I
A
C
W
V
W
N
A
E
G
W
L
V
K
L
G
S
L
D
YAGGLCV
H
L
T
S
G
H
G
G
L
V
Y
A
L
I
L
G
K
R
N
D
P
V
T
R
K
G
M
P
K
Y
K
PHS
V
T
S
-
V
V
L
G
T
V
F
L
W
F
G
W
M
F
F
N
G
G
S
A
G
N
A
T
I
R
A
W
Y
S
I
M
S
T
N
L
A
A
A
C
-------
G
G
L
T
W
M
V
I
D
Y
F
R
C
G
R
K
WT
T
V
G
L
C
---
S
G
I
--------
I
A
G
L
V
G
I
T
P
AA
G
F
V
P
I
W
S
A
V
V
I
G
V
V
T
G
A
G
C
N
L
A
V
D
L
K
S
L
L
RIDD
G
L
D
C
Y
S
I
H
G
V
G
G
C
I
G
S
V
L
T
G
I
F
A
A
D
Y
V
N
A
T
A
G
S
Y
I
S
P
I
D
GGWINHHYK
Q
V
G
Y
Q
L
A
G
I
C
A
A
L
A
W
T
V
T
V
T
S
I
L
L
L
T
M
N
A
I
P
F
L
K
L
R
L
S
A
D
E
E
E
L
G
T
D
AAQIGEFTYEESTAYIPEPIRS
8
Fugue
80.63
16%
-74
- C8 -
3ZPJ
-
?
A:
[1-356]
M
T
T
L
E
E
I
N
L
L
V
E
R
-
G
Y
Y
E
E
A
L
A
K
V
Y
E
I
E
D
---------
P
I
E
Q
V
Q
V
L
T
K
I
V
V
T
I
Y
Q
H
D
G
----
P
M
E
W
I
P
S
I
M
E
D
A
M
Y
I
A
K
K
L
R
D
P
A
N
K
A
----
V
A
Y
S
I
I
A
S
T
L
A
I
M
E
Y
E
E
D
A
M
D
F
F
N
R
A
I
D
E
A
N
E
I
E
S
P
I
E
K
-----
G
M
V
L
S
T
--
L
A
Y
H
L
-
A
I
A
G
Y
P
D
N
A
----
L
E
I
F
N
I
A
F
D
T
I
I
G
A
E
T
S
Y
T
H
K
---
V
D
G
I
L
R
I
G
D
L
L
E
K
A
G
D
T
L
P
S
N
E
A
M
D
F
Y
K
M
A
F
D
I
F
D
K
L
HV---------------
N
Q
R
A
A
I
V
E
K
K
I
E
L
A
K
T
V
Y
-----
D
V
G
L
P
Q
I
R
---
A
A
L
-
L
K
G
K
------------------------------
N
H
Y
A
L
A
-------
I
I
K
K
K
Y
S
G
V
M
R
L
I
G
E
L
--
E
V
A
L
W
---
M
K
R
---------
V
N
N
M
E
Y
L
D
--
V
V
D
K
A
F
E
C
C
E
S
P
R
F
--------
T
D
V
N
V
Q
H
----
I
A
R
L
L
T
E
L
G
----------
N
L
R
R
A
L
K
F
A
K
E
I
Q
N
I
H
K
R
S
E
---------------
A
L
K
A
I
A
L
E
L
V
R
R
K
K
F
E
E
V
K
K
I
I
E
S
I
-
P
D
P
K
I
R
E
E
A
L
N
E
I
G
T
IE--------------------
2
PsiBlast_PDB
45.19
33%
-22
- C8 -
3UF0
1
?
A:
[119-212]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
A
P
A
E
-
E
V
S
L
G
R
W
R
---
E
V
L
T
V
N
L
D
A
A
W
V
---------
L
S
R
S
F
G
T
A
M
L
A
H
G
S
G
R
I
V
T
I
A
S
M
LSFQGGR
N
V
A
A
Y
A
A
S
K
H
A
V
V
-
G
L
--
T
R
A
L
A
S
E
W
A
G
R
--------
G
V
G
V
N
A
L
A
P
--
G
Y
V
V
--------------------------------------------------------------------------------------------------------------------------------------------------
16
Fugue
41.07
14%
-58
- C6 -
4IUM
3
UBC_HUMAN
A:
[1-127]
----------------------------------------------------------------------------
G
Y
N
P
P
G
D
G
A
C
G
Y
----
R
C
L
A
F
M
N
G
A
T
V
V
S
A
G
C
S
S
D
L
W
C
D
D
E
L
A
Y
R
V
F
Q
L
S
P
T
F
T
V
T
I
PGG
R
V
C
P
N
A
K
Y
A
M
I
C
D
K
Q
H
W
R
-
V
K
R
A
KGVG
L
C
L
D
E
S
C
F
R
G
I
C
N
C
Q
R
M
--
S
G
---
P
P
P
A
P
V
S
A
A
V
L
D
H
I
L
E
A
A
T
F
G
N
V
R
V
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
38.61
29%
-37
- C8 -
4AGF
-
MSCS_ECOLI
A:
[107-171]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
G
L
A
L
Q
G
S
L
S
N
L
A
A
G
V
L
C
V
-------
M
F
R
P
F
R
A
G
E
Y
V
D
L
G
G
V
--
A
G
T
V
L
---
S
V
Q
IF
S
T
T
M
R
T
A
D
G
K
I
I
V
I
P
--
N
G
K
I
I
-------------------------------------------------------------------------------------------------------------------------------------------------
12
Fugue
36.42
25%
627
- C4 -
4N3C
1
B:
[5-24]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
N
P
P
C
E
T
H
E
T
G
T
T
N
T
A
T
T
A
T
------------------------------
13
Fugue
35.73
34%
107
- C8 -
3J1R
-
?
A:
[8-33]
------------------------------------------
V
S
P
V
I
A
T
L
L
L
I
L
I
A
V
A
A
A
V
L
L
Y
T
W
V
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
34.78
15%
-34
* C8 *
2MFR
-
A:
[1-57]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
T
Y
F
Y
V
T
D
Y
L
D
V
P
S
N
I
A
K
I
I
----
I
G
P
L
I
F
V
F
L
F
S
V
V
I
G
S
I
Y
L
F
L
R
K
R
Q
P
D
G
P
L
E
H
H
H
H
H
H
--------------------------------------------------------------------------------
14
Fugue
31.72
40%
123
- C8 -
4QKC
6
M2_I72A2
A:
[2-26]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
S
D
P
L
V
V
A
A
S
I
I
G
----
I
L
H
L
I
L
W
I
L
D
R
L
---------------------------------------------------------------------------------------------------------
15
Fugue
31.33
40%
145
- C8 -
2KQT
3
M2_I97A1
A:
[1-25]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
S
D
P
L
V
V
A
A
S
I
I
G
----
I
L
H
L
I
L
W
I
L
D
R
L
---------------------------------------------------------------------------------------------------------
10
Fugue
30.15
28%
535
- C5 -
3AA1
1
C:
[2-22]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
L
A
H
P
T
R
D
R
A
K
I
Q
H
S
R
R
P
P
T
R
------------------------------------------------------------------------------
6
HHSearch
28.91
13%
79
- C7 -
1ZZA
-
SNN_HUMAN
A:
[27-66]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
A
L
I
L
G
C
W
C
Y
L
R
L
Q
R
I
S
Q
S
E
--
D
E
E
S
I
V
G
D
G
---------------
E
T
K
E
P
F
L
L
V
Q
-----------------------------------------------------
7
HHSearch
15.54
8%
1035
- C3 -
1WA7
-
B:
[3-14]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
G
M
P
T
P
P
L
-
P
P
R
P
----------------------------------------------
5
HHSearch
5.63
14%
1457
- C2 -
2Z73
1
OPSD_TODPA
A:
[259-265]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
K
I
S
I
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
HHSearch
1.30
33%
1736
- C1 -
2Z73
1
OPSD_TODPA
A:
[270-275]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
L
L
S
W
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------