@TOME V2.3
(Nov 2016)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv1873: (2016-05-05 )
MKSASDPFDLKRFVYAQAPVYRSVVEELRAGRKRGHWMWFVFPQLRGLGSSPLAVRYGISSLEEAQAYLQHDLLGPRLHECTGLVNQVQGRSIEEIFGPPDDLKLCSSMTLFARATDANQDFVALLAKYYGGGEDRRTVALLAVT
Atome Classification :
(20 SA)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.----------........10........20........30........40..---....-..50........60-...-......---70........--80.-.......90........100.....-..110.......120.......130.....--..140...------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M----------KSAS
D
P
F
D
L
K
R
F
V
YAQA
P
V
Y
R
S
V
V
E
E
L
R
AGRKRG
H
W
M
W
F
V
F
P
---
Q
L
RG-LGSS
P
L
A
V
RYGI
S
--
S
L
E
-
E
A
Q
A
Y
L
---
Q
H
DLLG
P
R
L
H
--
E
C
T
-
G
L
V
N
Q
VQGR
S
I
E
E
IFGP
P
D
D
L
K
L
C
S-S
M
T
L
F
A
RATDA
N
Q
D
F
V
A
L
L
A
K
Y
YGGGED
R
R
--
T
V
A
L
L
A
VT------------------------------------------------------------------------
20
HHSearch
98.24
100%
-122
- C6 -
2JEK
3
?
A:
[6-145]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
F
D
L
K
R
F
V
Y
A
Q
A
P
V
Y
R
S
V
V
E
E
L
R
A
G
R
K
R
G
H
W
M
W
F
V
F
P
---
Q
L
R
G
-
L
G
S
S
P
L
A
V
R
Y
G
I
S
--
S
L
E
-
E
A
Q
A
Y
L
---
Q
H
D
L
L
G
P
R
L
H
--
E
C
T
-
G
L
V
N
Q
V
Q
G
R
S
I
E
E
I
F
G
P
P
D
D
L
K
L
C
S
-
S
M
T
L
F
A
R
A
T
D
A
N
Q
D
F
V
A
L
L
A
K
Y
Y
G
G
G
E
D
R
R
--
T
V
A
L
L
A
V
T
------------------------------------------------------------------------
1
PsiBlast_PDB
96.50
100%
-122
- C6 -
2JEK
3
?
A:
[6-145]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
F
D
L
K
R
F
V
Y
A
Q
A
P
V
Y
R
S
V
V
E
E
L
R
A
G
R
K
R
G
H
W
M
W
F
V
F
P
---
Q
L
R
G
-
L
G
S
S
P
L
A
V
R
Y
G
I
S
--
S
L
E
-
E
A
Q
A
Y
L
---
Q
H
D
L
L
G
P
R
L
H
--
E
C
T
-
G
L
V
N
Q
V
Q
G
R
S
I
E
E
I
F
G
P
P
D
D
L
K
L
C
S
-
S
M
T
L
F
A
R
A
T
D
A
N
Q
D
F
V
A
L
L
A
K
Y
Y
G
G
G
E
D
R
R
--
T
V
A
L
L
A
V
T
------------------------------------------------------------------------
41
Fugue
50.96
18%
-71
* C7 *
1UB9
-
?
A:
[1-100]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
E
E
L
K
E
I
M
K
S
H
I
L
G
N
P
V
R
L
G
I
M
I
F
L
L
P
R
R
K
A
P
------
F
S
---
Q
I
Q
K
V
L
D
L
T
P
G
N
L
D
S
H
I
R
--
V
L
E
-
R
N
-----------------------
G
L
V
K
T
Y
K
V
I
A
----------
D
R
P
R
T
-
V
V
E
I
T
D
F
G
M
E
E
A
K
R
F
L
S
S
L
K
A
V
I
D
G
L
D
L
------------------------------------------------------------------------------------
34
Fugue
49.45
16%
-64
- C7 -
1PA7
2
MARE1_HUMAN
A:
[1-130]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
V
N
V
Y
STSVT
S
D
N
L
S
R
H
D
M
L
A
W
I
N
E
S
L
Q
L
N
L
T
K
I
E
Q
L
C
S
G
A
A
Y
C
Q
F
M
D
M
L
F
P
GSI
A
L
K
K
-
V
K
F
Q
A
K
L
E
H
E
Y
I
Q
--
N
F
K
-
I
L
Q
A
G
F
---
K
R
M
G
V
D
K
I
I
-------------------------------
P
-
V
D
K
L
V
K
G
K
F
Q
D
N
F
E
F
V
Q
W
F
K
K
F
F
D
A
N
Y
D
G
K
--
D
Y
D
P
V
A
A
R
------------------------------------------------------------------------
33
Fugue
47.19
15%
-41
- C7 -
4KT3
-
?
A:
[29-177]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
L
C
N
N
I
S
A
V
T
F
V
S
K
Y
K
A
V
C
Q
P
I
A
D
Q
L
--
D
L
P
V
E
N
L
L
G
L
A
A
Q
---
E
S
Q
Y
--
G
T
G
R
I
A
R
E
L
N
-
N
--
Y
F
S
M
H
A
P
A
P
L
---
Q
I
G
A
E
A
P
S
I
K
--
V
A
K
-
F
D
S
F
Q
K
S
A
Q
S
F
A
S
S
F
G
T
A
V
R
G
Q
R
D
P
M
A
F
A
Q
A
L
V
R
S
G
Y
N
T
----------
G
N
G
R
D
G
F
--
A
R
Y
L
A
D
I
I
I
A
V
R
G
R
M
A
C---------------------------------------------------------------
10
PsiBlast_PDB
43.92
34%
-76
- C6 -
1IHP
-
PHYA_ASPNG
A:
[214-277]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
---
E
N
D
L
S
G
V
T
L
T
D
T
E
V
T
-
Y
L
M
D
M
C
---
S
F
D
T
I
S
T
----
T
K
L
S
P
-
F
C
D
L
F
T
H
D
E
W
I
N
Y
D
Y
L
Q
S
L
K
K
Y
Y
G
H
G
--------------------------------------------------------------------------------------
11
PsiBlast_PDB
43.64
34%
-69
- C6 -
3K4P
1
PHYA_ASPNG
A:
[220-283]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
---
E
N
D
L
S
G
V
T
L
T
D
T
E
V
T
-
Y
L
M
D
M
C
---
S
F
D
T
I
S
T
S
T
V
D
T
K
L
S
P
-
F
C
D
L
F
T
H
D
E
W
I
N
Y
D
Y
L
Q
S
L
K
K
Y
Y
G
H
G
--------------------------------------------------------------------------------------
36
Fugue
42.96
16%
-32
- C7 -
1V4R
-
?
A:
[1-100]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
----------
P
Y
K
A
P
E
----------
G
K
G
Y
A
D
V
A
T
H
F
R
T
L
I
K
S
G
E
L
A
----
P
---
G
D
T
L
-
P
S
V
A
D
I
R
A
Q
F
G
V
A
A
K
T
V
S
-
R
A
L
A
V
L
---
K
S
E
-------------
G
L
V
S
S
R
G
A
L
G
-------------------
T
V
V
E
K
N
P
I
V
I
T
G
A
D
R
L
K
R
M
E
K
N
G
M
R
Y
A
--
P
G
E
-----------------------------------------------------------------------------
12
PsiBlast_PDB
42.74
34%
-67
- C6 -
3K4Q
2
PHYA_ASPNG
A:
[220-283]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
---
E
N
D
L
S
G
V
T
L
T
D
T
E
V
T
-
Y
L
M
D
M
C
---
S
F
D
T
I
S
T
S
T
V
D
T
K
L
S
P
-
F
C
D
L
F
T
H
D
E
W
I
N
Y
D
Y
L
Q
S
L
K
K
Y
Y
G
H
G
--------------------------------------------------------------------------------------
39
Fugue
41.37
25%
-103
- C6 -
1HA8
-
MER23_EUPRA
A:
[1-51]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
--
E
C
E
-
Q
C
F
S
D
--
G
G
D
C
T
T
C
F
N
--
N
G
T
G
P
C
A
-
N
C
L
A
G
Y
P
A
G
C
S
N
S
D
C
T
A
F
L
S
Q
C
Y
G
G
C
--------------------------------------------------------------------------------------
37
Fugue
41.05
25%
-46
- C5 -
3WOL
10
DAPB2_PSEMX
A:
[1-696]
GEGMWVPQQLPEI
A
G
P
L
K
K
A
GLKLS
P
Q
Q
I
S
DLTGDPMGAVVALGG
C
T
A
S
F
VSPNG
L
V
V
T
N
HHCA
Y
G
A
I
Q
L
N
STAENNLIK
N
G
F
N
A
PTTADEVSAGPN
A
R
V
F
V
L
D
E
ITDV
T
K
D
A
K
A
A
I
A
A
A
GDD
A
L
A
R
T
K
A
L
E
A
F
E
K
K
L
I
A
D
C
E
AEAG
F
R
C
R
L
Y
S
F
SGGN
T
Y
R
L
F
K
N
LEIKDVRLA
Y
A
P
P
G
S
V
G
K
FGGDIDNWMWPRHTGD
F
A
F
Y
R
A
Y
V
G
KDG
K
P
A
A
F
SKDN
V
P
Y
Q
P
K
H
W
L
K
F
A
D
Q
P
L
G
AG
D
F
V
M
V
A
G
Y
P
G
S
TNRYAL
A
A
E
F
D
N
T
A
Q
W
T
Y
P
T
I
A
R
H
Y
K
N
Q
I
A
M
V
E
A
A
G
K
Q
N
A
D
I
Q
V
K
Y
A
A
T
M
A
G
W
N
N
T
S
K
N
Y
D
G
Q
L
E
G
F
K
R
I
D
A
A
G
Q
K
L
R
E
E
A
A
V
L
G
W
L
K
G
Q
GAKG
Q
P
A
L
D
A
H
A
K
L
L
D
L
L
E
Q
S
K
A
T
R
D
R
D
L
T
L
A
L
F
N
N
TA
M
L
G
S
A
T
Q
L
Y
R
L
S
I
E
R
E
K
PNAERESGYQERD
L
P
A
I
E
G
G
L
K
Q
L
E
RRYV
A
A
M
D
R
Q
L
Q
E
Y
W
L
N
E
Y
I
K
LPADQRV
A
A
V
D
A
W
L
GGND
A
A
A
V
K
R
A
L
D
R
L
A
G
TKLGS
T
E
E
R
L
K
W
F
A
AD
R
K
A
F
E
A
SND
P
A
I
Q
Y
A
V
A
V
M
P
T
L
L
----------
K
L
E
Q
E
R
K
T
R
A
G
E
N
L
A
A
R
P
V
Y
L
Q
A
L
A
D
Y
K
K
S
Q
G
E
-----
F
V
Y
P
----------
D
A
N
L
S
L
R
I
T
F
G
--
N
V
M
----
G
Y
A
---
P
K
D
--
G
M
E
Y
T
--
P
F
T
-
T
L
E
G
V
V
A
K
E
T
G
Q
D
P
F
D
S
P
K
A
L
L
D
A
V
-
A
------------------
A
K
R
Y
G
G
L
E
D
K
R
IG
S
V
P
V
N
Y
L
S
D
L
D
I
T
GGNSG
S
P
V
L
D
AHGKLV
G
L
A
F
DGNWESVSSNWVFDPKM
T
R
M
I
A
V
D
G
R
Y
L
R
W
I
M
Q
EVYPA
P
Q
L
L
K
E
M
NV
40
Fugue
33.22
21%
-42
- C4 -
1GH9
-
PA84_METTH
A:
[1-71]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
Y
I
I
F
--
R
C
D
-
C
G
R
A
L
Y
---
S
R
E
--
G
A
K
T
R
--
K
C
V
C
G
R
T
V
N
V
K
D
R
R
I
---
F
G
R
A
D
D
F
E
E
A
S
-
E
L
V
R
K
L
Q
E
E
K
Y
G
S
C
H
F
T
N
P
S
K
R
E
-----------------------------------------------------------------------------------------
19
PsiBlast_PDB
32.62
70%
9
- C6 -
5AES
-
PLPP_MOUSE
A:
[257-276]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
V
S
--
S
L
E
-
E
A
Q
A
Y
L
T
A
G
Q
R
D
L
V
-----------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
32.24
70%
10
- C6 -
4BX2
-
PLPP_MOUSE
A:
[257-276]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
V
S
--
S
L
E
-
E
A
Q
A
Y
L
T
A
G
Q
R
D
L
V
-----------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
32.10
51%
-10
- C6 -
2CFR
-
PLPP_HUMAN
A:
[253-281]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
M
T
T
V
L
T
L
T
G
V
S
--
R
L
E
-
E
A
Q
A
Y
L
A
A
G
Q
H
D
L
V
-----------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
31.92
70%
12
- C6 -
4BX3
-
PLPP_MOUSE
A:
[257-276]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
V
S
--
S
L
E
-
E
A
Q
A
Y
L
T
A
G
Q
R
D
L
V
-----------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
31.60
51%
-12
- C6 -
4BKM
-
PGP_MOUSE (first)
A:
[264-292]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
M
T
T
V
L
T
L
T
G
V
S
--
S
L
E
-
E
A
Q
A
Y
L
T
A
G
Q
R
D
L
V
-----------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
31.16
51%
-2
- C6 -
4BX0
-
?
A:
[247-275]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
M
T
T
V
L
T
L
T
G
V
S
--
S
L
E
-
E
A
Q
A
Y
L
T
A
G
Q
R
D
L
V
-----------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
30.89
70%
5
- C6 -
2CFT
1
PLPP_HUMAN
A:
[262-281]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
V
S
--
R
L
E
-
E
A
Q
A
Y
L
A
A
G
Q
H
D
L
V
-----------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
30.68
51%
-4
- C6 -
2OYC
-
PLPP_HUMAN
A:
[253-281]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
M
T
T
V
L
T
L
T
G
V
S
--
R
L
E
-
E
A
Q
A
Y
L
A
A
G
Q
H
D
L
V
-----------------------------------------------------------------------------------------------------------------------------------------------------