@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv1888A: (2016-05-05 )
MVPVDLRRDWPTPLRQAGFDPNQPSAWLAEGLLAFLPPDAQDRLLDNITALSAPGSR
Atome Classification :
(20 SA)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.......--..10--......-..-.20........30........-40........50......------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVPVDLR--RDW---PT
P
L
R
Q-AG-FDPNQ
P
S
A
W
L
A
E
G
L
L
A
FLPP
D
-
A
Q
D
R
L
L
D
N
I
TALSAPGSR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
94.57
63%
-104
- C5 -
2UYO
-
Y2640_MYCLE
A:
[157-222]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
V
P
I
D
L
R
--
Q
D
W
---
P
P
A
L
R
S
-
A
G
-
F
D
P
S
A
R
T
A
W
L
A
E
G
L
L
M
Y
L
P
A
T
-
A
Q
D
G
L
F
T
E
I
G
G
L
S
A
V
G
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
94.36
64%
-96
- C5 -
2UYO
-
Y2640_MYCLE
A:
[158-223]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
I
D
L
R
--
Q
D
W
---
P
P
A
L
R
S
-
A
G
-
F
D
P
S
A
R
T
A
W
L
A
E
G
L
L
M
Y
L
P
A
T
-
A
Q
D
G
L
F
T
E
I
G
G
L
S
A
V
G
S
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
93.82
63%
-95
- C5 -
2CKD
-
Y2640_MYCLE
A:
[8-310]
---------------------------WDIKT
S
V
G
T
T
A
V
M
V
A
A
A
R
A
A
E
T
D
RPDALIRDPY
A
K
L
L
V
T
N
T
GAG
A
L
W
E
A
M
L
DPSM
V
A
K
V
E
A
I
D
A
E
A
A
A
M
V
E
H
M
R
S
Y
Q
A
V
R
T
N
F
F
D
T
Y
F
N
N
A
V
I
D
GIR
Q
F
V
I
L
ASGLDSRAYR
L
D
W
P
T
G
T
T
V
Y
E
I
D
Q
P
K
V
L
A
Y
K
S
T
T
L
A
E
H
GVTPTADRR
E
V
P
I
D
L
R
--
Q
D
W
---
P
P
A
L
R
S
-
A
G
-
F
D
P
S
A
R
T
A
W
L
A
E
G
L
L
M
Y
L
P
A
T
-
A
Q
D
G
L
F
T
E
I
G
G
L
S
A
V
G
S
R
I
A
V
E
T
S
P
LH
G
D
E
W
R
E
Q
M
Q
L
R
F
R
R
V
S
D
A
L
GFE
Q
A
V
D
V
QELIYHDENRAV
V
A
D
W
L
N
R
H
GWR
A
T
A
Q
S
A
P
D
E
M
R
R
V
GRWGDGVPMADDKDA
F
A
E
F
V
T
A
H
R
L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
93.62
64%
-95
- C5 -
2UYQ
1
Y2640_MYCLE
A:
[158-224]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
I
D
L
R
--
Q
D
W
---
P
P
A
L
R
S
-
A
G
-
F
D
P
S
A
R
T
A
W
L
A
E
G
L
L
M
Y
L
P
A
T
-
A
Q
D
G
L
F
T
E
I
G
G
L
S
A
V
G
S
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
93.27
64%
-99
- C5 -
2CKD
-
Y2640_MYCLE
A:
[158-213]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
I
D
L
R
--
Q
D
W
---
P
P
A
L
R
S
-
A
G
-
F
D
P
S
A
R
T
A
W
L
A
E
G
L
L
M
Y
L
P
A
T
-
A
Q
D
G
L
F
T
E
I
G
G
L
S
A
V
G
S
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
77.72
27%
-60
* C5 *
2ZWA
6
TYW4_YEAST
A:
[16-694]
Q
E
R
R
K
K
Y
A
D
L
A
I
Q
G
T
N
N
S
S
I
A
S
K
R
S
V
E
L
LYLPKLSSANNFQMDKNN
K
L
L
E
Y
FKFFVP
K
K
I
K
R
S
P
C
I
N
R
G
Y
W
L
R
L
F
A
I
R
S
R
L
N
S
I
I
E
Q
TPQD
K
K
I
V
V
V
N
L
GCGYDP
L
P
F
Q
L
L
DTNNIQSQQYHDR
V
S
F
I
D
I
D
Y
S
D
L
L
K
I
K
I
E
L
I
K
T
I
P
E
L
S
K
I
I
GLSEDKDYVDDSNVD
F
L
T
T
PK
Y
L
A
R
P
C
D
L
N
D
S
K
M
F
---
S
T
L
L
N
E
-
C
Q
L
Y
D
P
N
V
V
K
V
F
V
A
E
V
S
L
A
Y
M
K
P
E
-
R
S
D
S
I
I
E
A
T
S
K
M
--
E
N
S
H
F
I
I
L
E
Q
L
IPKGPFE
P
F
S
K
Q
M
L
A
H
F
K
R
N
DSPLQ
S
V
L
K
Y
NT
I
E
S
Q
V
Q
R
F
N
K
L
GFA
Y
V
N
V
G
D
M
F
Q
L
W
E
S
AD
E
A
T
K
K
E
L
L
K
VEPFDE
L
E
E
F
H
L
F
C
H
H
Y
V
L
C
H
A
T
NYKEFAFTQGFLFDRINLTVDED
Y
Q
L
L
E
C
E
C
PINRKF
G
D
V
D
V
AGN
D
V
F
Y
M
G
GSNPYRVN
E
I
L
Q
L
S
I
H
YD
K
I
D
M
K
N
I
E
V
SSSEVPVARMC
H
T
F
T
T
I
SRNN
Q
L
L
L
I
G
GRKAPHQGLS
D
N
W
I
F
D
MKTR
E
W
S
M
I
KSLS
H
T
R
F
R
H
S
A
C
S
L
PDG
N
V
L
I
L
G
GVTEGPA
M
L
L
Y
NVTEEIFKDVTPKDEFFQ
N
S
L
V
S
A
G
L
E
F
D
PVSK
Q
G
I
I
L
G
GGFMDQTTVSDKA
I
I
F
K
Y
D
AENATEPITVI
K
K
L
Q
H
PLFQRYG
S
Q
I
K
Y
ITPR
K
L
L
I
V
G
G
T
S
PS
G
L
F
D
RTNS
I
I
S
L
DPLSE
T
L
T
S
IPIS
R
R
I
W
E
D
H
SLMLAG
F
S
L
V
S
TT
I
H
I
I
G
G
G
A
TCYGF
G
S
V
T
N
V
G
L
K
L
I
A
IA
11
HHSearch
71.91
21%
-100
- C5 -
3IEI
1
LCMT1_HUMAN
A:
[167-221]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
I
G
A
D
L
R
D
L
S
E
L
---
E
E
K
L
K
K
-
C
N
-
M
N
T
Q
L
P
T
L
L
I
A
E
C
V
L
V
Y
M
T
P
E
-
Q
S
A
N
L
L
K
W
A
A
N
S
F
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
69.31
19%
-59
- C5 -
1RJD
3
LCMT1_YEAST
A:
[2-329]
-------E
R
I
I
Q
Q
T
D
Y
D
A
L
S
C
K
L
A
A
I
S
V
GYLPSSGLQRLS
V
D
L
S
K
K
Y
T
E
W
H
R
S
Y
L
I
T
L
K
K
F
S
R
R
A
F
G
K
V
D
K
A
M
R
S
SF
P
V
M
N
Y
G
T
Y
L
R
T
V
G
I
D
A
A
I
L
E
F
L
V
A
N
E
K
V
Q
V
V
N
L
GCGSDL
R
M
L
P
L
L
Q
M
F
P
H
L
A
Y
V
D
I
D
Y
N
E
S
V
E
L
K
N
S
I
L
R
E
S
E
I
L
R
I
S
L
GLSKEDTAKSPFLIDQGR
Y
K
L
A
A
C
D
L
N
D-
I
T
E
---
T
T
R
L
L
D
-
V
C
-
T
K
R
E
I
P
T
I
V
I
S
E
C
L
L
C
Y
M
H
N
N
-
E
S
Q
L
L
I
N
T
I
M
S
K
F
S
H
G
L
W
I
S
Y
D
P
I
GGSQPNDR
F
G
A
I
M
Q
S
N
L
K
E
S
RNLEMPTLMTYNS
K
E
K
Y
A
S
R
W
SAAP
N
V
I
V
N
D
M
W
E
I
F
N
AQIP
E
S
E
R
K
R
L
R
S
L
QFLDE
L
E
E
L
K
V
M
Q
T
H
Y
I
L
M
K
A
Q
W
H-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
65.17
25%
-48
- C5 -
2ZWA
1
TYW4_YEAST
A:
[192-256]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
P
C
D
L
N
D
S
K
M
F
---
S
T
L
L
N
E
C
Q
L
-
Y
D
P
N
V
V
K
V
F
V
A
E
V
S
L
A
Y
M
K
P
E
-
R
S
D
S
I
I
E
A
T
S
K
-
M
E
N
S
H
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
60.90
20%
-72
- C5 -
1RJD
2
LCMT1_YEAST
A:
[171-227]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
A
C
D
L
N
D-
I
T
E
---
T
T
R
L
L
D
-
V
C
-
T
K
R
E
I
P
T
I
V
I
S
E
C
L
L
C
Y
M
H
N
N
-
E
S
Q
L
L
I
N
T
I
M
S
K
F
S
H
G
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
49.67
27%
-96
- C5 -
2ZW9
1
TYW4_YEAST
A:
[213-248]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
D
P
N
V
V
K
V
F
V
A
E
V
S
L
A
Y
M
K
P
E
-
R
S
D
S
I
I
E
A
T
S
K
M
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
48.66
27%
-86
- C5 -
2ZWA
1
TYW4_YEAST
A:
[213-252]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
D
P
N
V
V
K
V
F
V
A
E
V
S
L
A
Y
M
K
P
E
-
R
S
D
S
I
I
E
A
T
S
K
M
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
47.99
27%
-88
- C5 -
2ZZK
1
TYW4_YEAST
A:
[213-247]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
D
P
N
V
V
K
V
F
V
A
E
V
S
L
A
Y
M
K
P
E
-
R
S
D
S
I
I
E
A
T
S
K
M
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
44.78
20%
-114
- C5 -
3CQB
2
HTPX_VIBPA
A:
[65-89]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
S
L
V
A
V
S
T
G
L
L
H
N
M
T
R
D
-
E
A
E
A
V
L
A
H
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
44.49
22%
-23
- C5 -
2HIN
2
?
A:
[1-66]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
P
E
E
L
V
--
R
H
F
GD
V
E
K
A
A
V
G
-
V
G
-
V
T
P
G
A
V
Y
Q
W
L
Q
A
G
E
I
----
P
P
-
L
R
Q
S
D
I
E
V
R
T
A
Y
K
L
K
S
D
F
T
S
Q
R
M
GKEGH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
HHSearch
44.10
15%
-88
- C5 -
1AF7
1
CHER_SALTY
A:
[212-244]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
P
F
D
A
I
F
C
R
N
V
M
I
Y
F
D
K
T
-
T
Q
E
D
I
L
R
R
F
V
P
L
L
K
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
42.33
19%
-84
- C5 -
1WJK
-
YD286_MOUSE
A:
[65-96]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
D
I
P
V
F
H
L
-
N
G
Q
F
L
M
M
H
R
V
-
N
T
S
K
L
E
K
Q
L
R
K
L
S
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
40.93
11%
-86
- C5 -
3GIW
2
?
A:
[154-192]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
T
-
L
D
L
T
R
P
V
A
L
T
V
I
A
I
V
H
F
V
L
D
E
D
D
A
V
G
I
V
R
R
L
L
E
P
L
P
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
Fugue
39.43
16%
-65
- C5 -
2WUJ
-
DIV4A_BACSU
A:
[3-52]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
P
N
D
I
H
N-
K
T
F
---
T
K
S
F
R
---
G
-
Y
D
E
D
E
V
N
E
F
L
A
Q
V
R
K
D
Y
E
I
V
L
-
R
K
K
T
E
L
E
A
K
V
N
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
36.56
22%
-61
- C5 -
1PJZ
-
TPMT_PSESJ
A:
[99-130]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
C
A
A
F
Y
D
R
A
A
M
I
A
L
P
A
D
-
M
R
E
R
Y
V
Q
H
L
E
A
L
M
P
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------