@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv2780: (2016-05-13 )
MRVGIPTETKNNEFRVAITPAGVAELTRRGHEVLIQAGAGEGSAITDADFKAAGAQLVGTADQVWADADLLLKVKEPIAAEYGRLRHGQILFTFLHLAASRACTDALLDSGTTSIAYETVQTADGALPLLAPMSEVAGRLAAQVGAYHLMRTQGGRGVLMGGVPGVEPADVVVIGAGTAGYNAARIANGMGATVTVLDINIDKLRQLDAEFCGRIHTRYSSAYELEGAVKRADLVIGAVLVPGAKAPKLVSNSLVAHMKPGAVLVDIAIDQGGCFEGSRPTTYDHPTFAVHDTLFYCVANMPASVPKTSTYALTNATMPYVLELADHGWRAACRSNPALAKGLSTHEGALLSERVATDLGVPFTEPASVLA
Atome Classification :
(27 SA)
.........10........20........30........40........50........60........70........80....-----.....90........100.......110.......120....--...130.......140.......150.......160.......170.......180.......190.......200.......210.....--------..220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.....--..330.......340.......350.......360.......370
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MRVGIPTETKNN
E
F
R
V
A
ITP
A
G
V
A
E
L
TRRG
H
E
V
L
I
Q
AGAGEGSAITD
A
D
F
KAAG
A
Q
L
VG
T
A
D
Q
VWAD
A
D
L
L
L
K
VKE
P
I
A
A
-
E
Y
GR-----LRH
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
LDSGTT
S
I
A
Y
E
T
VQTADGA--L
P
L
LA
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
RTQGG
R
G
V
L
MGGVPGVEPA
D
V
V
V
I
GAGTAGY
N
A
A
R
IANGMG
A
T
V
T
V
L
DI
N
I
D
K
L
R
Q
L
D
A
E
F
C
G
R
I
H
T
--------RYSSAYELEGAV
K
R
A
D
L
V
I
G
A
V
LVPGAKA
P
K
L
V
S
N
S
L
V
A
HMKP
G
A
V
L
V
D
I
A
IDQGGCFEGSRPTTYDHPT
F
A
V
H
D
T
L
F
Y
C
V
ANMPASVPKT
S
T
Y
A
LTNAT
M
P
Y
V
L
E
LADH--
G
W
R
A
A
CRSN
P
A
L
AKGLSTHE
G
A
L
L
S
E
R
V
A
T
DLGVPFTEPASVLA
29
PsiBlast_CBE
95.59
100%
-115
- C5 -
2VHW
1
DHA_MYCTU
C:
[1-371]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
V
W
A
D
A
D
L
L
L
K
V
K
E
P
I
A
A
-
E
Y
G
R
-----
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
T
V
Q
T
A
D
G
A
--
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
E
F
C
G
R
I
H
T
--------
R
Y
S
S
A
Y
E
L
E
G
A
V
K
R
A
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
D
Q
G
G
C
F
E
G
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
--
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
T
E
P
A
S
V
L
A
119
HHSearch
95.21
100%
-112
- C5 -
4LMP
8
?
A:
[1-371]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
V
W
A
D
A
D
L
L
L
K
V
K
E
P
I
A
A
-
E
Y
G
R
-----
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
T
V
Q
T
A
D
G
A
--
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
E
F
C
G
R
I
H
T
--------
R
Y
S
S
A
Y
E
L
E
G
A
V
K
R
A
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
D
Q
G
G
C
F
E
G
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
--
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
T
E
P
A
S
V
L
A
3
PsiBlast_PDB
95.21
100%
-112
- C5 -
4LMP
8
?
A:
[1-371]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
V
W
A
D
A
D
L
L
L
K
V
K
E
P
I
A
A
-
E
Y
G
R
-----
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
T
V
Q
T
A
D
G
A
--
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
E
F
C
G
R
I
H
T
--------
R
Y
S
S
A
Y
E
L
E
G
A
V
K
R
A
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
D
Q
G
G
C
F
E
G
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
--
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
T
E
P
A
S
V
L
A
28
PsiBlast_CBE
95.07
100%
-115
- C5 -
2VHW
1
DHA_MYCTU
D:
[1-370]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
V
W
A
D
A
D
L
L
L
K
V
K
E
P
I
A
A
-
E
Y
G
R
-----
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
T
V
Q
T
A
D
G
A
--
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
E
F
C
G
R
I
H
T
--------
R
Y
S
S
A
Y
E
L
E
G
A
V
K
R
A
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
D
Q
G
G
C
F
E
G
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
--
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
T
E
P
A
S
V
L
-
30
PsiBlast_CBE
95.04
100%
-114
- C5 -
2VHW
2
DHA_MYCTU
B:
[1-370]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
V
W
A
D
A
D
L
L
L
K
V
K
E
P
I
A
A
-
E
Y
G
R
-----
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
T
V
Q
T
A
D
G
A
--
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
E
F
C
G
R
I
H
T
--------
R
Y
S
S
A
Y
E
L
E
G
A
V
K
R
A
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
D
Q
G
G
C
F
E
G
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
--
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
T
E
P
A
S
V
L
-
4
PsiBlast_PDB
94.88
100%
-116
- C5 -
2VHW
2
DHA_MYCTU
A:
[1-371]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
V
W
A
D
A
D
L
L
L
K
V
K
E
P
I
A
A
-
E
Y
G
R
-----
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
T
V
Q
T
A
D
G
A
--
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
E
F
C
G
R
I
H
T
--------
R
Y
S
S
A
Y
E
L
E
G
A
V
K
R
A
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
D
Q
G
G
C
F
E
G
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
--
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
T
E
P
A
S
V
L
A
1
PsiBlast_PDB
94.71
100%
-112
- C5 -
2VOE
-
DHA_MYCTU
A:
[1-371]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
V
W
A
D
A
D
L
L
L
K
V
K
E
P
I
A
A
-
E
Y
G
R
-----
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
T
V
Q
T
A
D
G
A
--
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
E
F
C
G
R
I
H
T
--------
R
Y
S
S
A
Y
E
L
E
G
A
V
K
R
A
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
D
Q
G
G
C
F
E
G
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
--
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
T
E
P
A
S
V
L
A
5
PsiBlast_PDB
94.39
100%
-115
- C5 -
2VHX
2
DHA_MYCTU
A:
[1-371]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
V
W
A
D
A
D
L
L
L
K
V
K
E
P
I
A
A
-
E
Y
G
R
-----
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
T
V
Q
T
A
D
G
A
--
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
E
F
C
G
R
I
H
T
--------
R
Y
S
S
A
Y
E
L
E
G
A
V
K
R
A
D
L
V
I
G
A
V
L
V
---
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
D
Q
G
G
C
F
E
G
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
--
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
T
E
P
A
S
V
L
A
23
PsiBlast_CBE
94.03
100%
-109
- C5 -
2VHZ
1
DHA_MYCTU
B:
[1-371]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
V
W
A
D
A
D
L
L
L
K
V
K
E
P
I
A
A
-
E
Y
G
R
-----
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
T
V
Q
T
A
D
G
A
--
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
E
F
C
G
R
I
H
T
--------
R
Y
S
S
A
Y
E
L
E
G
A
V
K
R
A
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
D
Q
G
G
C
F
E
G
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
--
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
T
E
P
A
S
V
L
A
6
PsiBlast_PDB
93.79
100%
-109
- C5 -
2VHZ
1
DHA_MYCTU
A:
[1-371]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
V
W
A
D
A
D
L
L
L
K
V
K
E
P
I
A
A
-
E
Y
G
R
-----
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
T
V
Q
T
A
D
G
A
--
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
E
F
C
G
R
I
H
T
--------
R
Y
S
S
A
Y
E
L
E
G
A
V
K
R
A
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
D
Q
G
G
C
F
E
G
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
--
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
T
E
P
A
S
V
L
A
27
PsiBlast_CBE
93.42
100%
-109
- C5 -
2VHW
1
DHA_MYCTU
E:
[1-371]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
V
W
A
D
A
D
L
L
L
K
V
K
E
P
I
A
A
-
E
Y
G
R
-----
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
T
V
Q
T
A
D
G
A
--
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
E
F
C
G
R
I
H
T
--------
R
Y
S
S
A
Y
E
L
E
G
A
V
K
R
A
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
D
Q
G
G
C
F
E
G
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
--
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
T
E
P
A
S
V
L
A
31
PsiBlast_CBE
93.26
99%
-110
- C5 -
2VHV
1
DHA_MYCTU
B:
[1-371]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
V
W
A
D
A
D
L
L
L
K
V
K
E
P
I
A
A
-
E
Y
G
R
-----
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
T
V
Q
T
A
D
G
A
--
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
E
F
C
G
R
I
H
T
--------
R
Y
S
S
A
Y
E
L
E
G
A
V
K
R
A
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
N
Q
G
G
C
F
E
G
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
--
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
T
E
P
A
S
V
L
A
22
PsiBlast_CBE
93.05
100%
-108
- C5 -
2VOJ
2
DHA_MYCTU
C:
[1-371]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
V
W
A
D
A
D
L
L
L
K
V
K
E
P
I
A
A
-
E
Y
G
R
-----
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
T
V
Q
T
A
D
G
A
--
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
E
F
C
G
R
I
H
T
--------
R
Y
S
S
A
Y
E
L
E
G
A
V
K
R
A
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
D
Q
G
G
C
F
E
G
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
--
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
T
E
P
A
S
V
L
A
26
PsiBlast_CBE
93.04
100%
-108
- C5 -
2VHW
1
DHA_MYCTU
F:
[1-371]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
V
W
A
D
A
D
L
L
L
K
V
K
E
P
I
A
A
-
E
Y
G
R
-----
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
T
V
Q
T
A
D
G
A
--
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
E
F
C
G
R
I
H
T
--------
R
Y
S
S
A
Y
E
L
E
G
A
V
K
R
A
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
D
Q
G
G
C
F
E
G
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
--
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
T
E
P
A
S
V
L
A
24
PsiBlast_CBE
92.96
100%
-110
- C5 -
2VHX
3
DHA_MYCTU
F:
[1-371]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
V
W
A
D
A
D
L
L
L
K
V
K
E
P
I
A
A
-
E
Y
G
R
-----
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
T
V
Q
T
A
D
G
A
--
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
E
F
C
G
R
I
H
T
--------
R
Y
S
S
A
Y
E
L
E
G
A
V
K
R
A
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
D
Q
G
G
C
F
E
G
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
--
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
T
E
P
A
S
V
L
A
25
PsiBlast_CBE
92.95
100%
-109
- C5 -
2VHX
2
DHA_MYCTU
E:
[1-371]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
V
W
A
D
A
D
L
L
L
K
V
K
E
P
I
A
A
-
E
Y
G
R
-----
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
T
V
Q
T
A
D
G
A
--
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
E
F
C
G
R
I
H
T
--------
R
Y
S
S
A
Y
E
L
E
G
A
V
K
R
A
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
D
Q
G
G
C
F
E
G
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
--
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
T
E
P
A
S
V
L
A
7
PsiBlast_PDB
92.78
99%
-110
- C5 -
2VHV
1
DHA_MYCTU
A:
[1-371]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
V
W
A
D
A
D
L
L
L
K
V
K
E
P
I
A
A
-
E
Y
G
R
-----
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
T
V
Q
T
A
D
G
A
--
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
E
F
C
G
R
I
H
T
--------
R
Y
S
S
A
Y
E
L
E
G
A
V
K
R
A
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
N
Q
G
G
C
F
E
G
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
--
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
T
E
P
A
S
V
L
A
21
PsiBlast_CBE
92.67
100%
-108
- C5 -
2VOJ
2
DHA_MYCTU
E:
[1-371]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
V
W
A
D
A
D
L
L
L
K
V
K
E
P
I
A
A
-
E
Y
G
R
-----
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
T
V
Q
T
A
D
G
A
--
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
E
F
C
G
R
I
H
T
--------
R
Y
S
S
A
Y
E
L
E
G
A
V
K
R
A
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
D
Q
G
G
C
F
E
G
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
--
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
T
E
P
A
S
V
L
A
2
PsiBlast_PDB
92.23
100%
-108
- C5 -
2VOJ
2
DHA_MYCTU
A:
[1-371]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
V
W
A
D
A
D
L
L
L
K
V
K
E
P
I
A
A
-
E
Y
G
R
-----
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
T
V
Q
T
A
D
G
A
--
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
E
F
C
G
R
I
H
T
--------
R
Y
S
S
A
Y
E
L
E
G
A
V
K
R
A
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
D
Q
G
G
C
F
E
G
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
--
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
T
E
P
A
S
V
L
A
120
HHSearch
79.59
49%
-113
- C5 -
1PJC
1
?
A:
[1-359]
M
E
I
G
V
P
K
E
I
K
N
Q
E
F
R
V
G
L
S
P
S
S
V
R
T
L
V
E
A
G
H
T
V
F
I
E
T
Q
A
G
I
G
A
G
F
A
D
Q
D
Y
V
Q
A
G
A
Q
V
V
P
S
A
K
D
A
W
S
-
R
E
M
V
V
K
V
K
E
P
L
P
A
-
E
Y
D
L
-----
M
Q
K
D
Q
L
L
F
T
Y
L
H
L
A
A
A
R
E
L
T
E
Q
L
M
R
V
G
L
T
A
I
A
Y
E
T
V
E
L
P
N
R
S
--
L
P
L
L
T
P
M
S
I
I
A
G
R
L
S
V
Q
F
G
A
R
F
L
E
R
Q
Q
G
G
R
G
V
L
L
G
G
V
P
G
V
K
P
G
K
V
V
I
L
G
G
G
V
V
G
T
E
A
A
K
M
A
V
G
L
G
A
Q
V
Q
I
F
D
I
N
V
E
R
L
S
Y
L
E
T
L
F
G
S
R
V
E
L
--------
L
Y
S
N
S
A
E
I
E
T
A
V
A
E
A
D
L
L
I
G
A
V
L
V
P
G
R
R
A
P
I
L
V
P
A
S
L
V
E
Q
M
R
T
G
S
V
I
V
D
V
A
V
D
Q
G
G
C
V
E
T
L
H
P
T
S
H
T
Q
P
T
Y
E
V
F
G
V
V
H
Y
G
V
P
N
M
P
G
A
V
P
W
T
A
T
Q
A
L
N
N
S
T
L
P
Y
V
V
K
L
A
N
Q
--
G
L
K
-
A
L
E
T
D
D
A
L
A
K
G
L
N
V
Q
A
H
R
L
V
H
P
A
V
Q
Q
V
F
P
D
----------
139
Fugue
78.95
48%
-113
- C5 -
1PJC
1
?
A:
[1-361]
M
E
I
G
V
P
K
E
I
K
N
Q
E
F
R
V
G
L
S
P
S
S
V
R
T
L
V
E
A
G
H
T
V
F
I
E
T
Q
A
G
I
G
A
G
F
A
D
Q
D
Y
V
Q
A
G
A
Q
V
V
P
S
A
K
D
A
W
S
-
R
E
M
V
V
K
V
K
E
P
L
P
-A
E
Y
D
L
-----
M
Q
K
D
Q
L
L
F
T
Y
L
H
L
A
A
A
R
E
L
T
E
Q
L
M
R
V
G
L
T
A
I
A
Y
E
T
V
E
L
P
N
R
S
--
L
P
L
L
T
P
M
S
I
I
A
G
R
L
S
V
Q
F
G
A
R
F
L
E
R
Q
Q
G
G
R
G
V
L
L
G
G
V
P
G
V
K
P
G
K
V
V
I
L
G
G
G
V
V
G
T
E
A
A
K
M
A
V
G
L
G
A
Q
V
Q
I
F
D
I
N
V
E
R
L
S
Y
L
E
T
L
F
G
S
R
V
E
L
--------
L
Y
S
N
S
A
E
I
E
T
A
V
A
E
A
D
L
L
I
G
A
V
L
V
P
G
R
R
A
P
I
L
V
P
A
S
L
V
E
Q
M
R
T
G
S
V
I
V
D
V
A
V
D
Q
G
G
C
V
E
T
L
H
P
T
S
H
T
Q
P
T
Y
E
V
F
G
V
V
H
Y
G
V
P
N
M
P
G
A
V
P
W
T
A
T
Q
A
L
N
N
S
T
L
P
Y
V
V
K
L
A
N
Q
GL---
K
A
L
E
T
D
D
A
L
A
K
G
L
N
V
Q
A
H
R
L
V
H
P
A
V
Q
----
Q
V
F
P
D
L
A
----
11
PsiBlast_PDB
77.72
50%
-112
- C5 -
1PJC
1
?
A:
[1-344]
M
E
I
G
V
P
K
E
I
K
N
Q
E
F
R
V
G
L
S
P
S
S
V
R
T
L
V
E
A
G
H
T
V
F
I
E
T
Q
A
G
I
G
A
G
F
A
D
Q
D
Y
V
Q
A
G
A
Q
V
V
P
S
A
K
D
A
W
S
R
-
E
M
V
V
K
V
K
E
P
L
P
A
-
E
Y
D
L
-----
M
Q
K
D
Q
L
L
F
T
Y
L
H
L
A
A
A
R
E
L
T
E
Q
L
M
R
V
G
L
T
A
I
A
Y
E
T
V
E
L
P
N
R
S
--
L
P
L
L
T
P
M
S
I
I
A
G
R
L
S
V
Q
F
G
A
R
F
L
E
R
Q
Q
G
G
R
G
V
L
L
G
G
V
P
G
V
K
P
G
K
V
V
I
L
G
G
G
V
V
G
T
E
A
A
K
M
A
V
G
L
G
A
Q
V
Q
I
F
D
I
N
V
E
R
L
S
Y
L
E
T
L
F
G
S
R
V
E
L
--------
L
Y
S
N
S
A
E
I
E
T
A
V
A
E
A
D
L
L
I
G
A
V
L
V
P
G
R
R
A
P
I
L
V
P
A
S
L
V
E
Q
M
R
T
G
S
V
I
V
D
V
A
V
D
Q
G
G
C
V
E
T
L
H
P
T
S
H
T
Q
P
T
Y
E
V
F
G
V
V
H
Y
G
V
P
N
M
P
G
A
V
P
W
T
A
T
Q
A
L
N
N
S
T
L
P
Y
V
V
K
L
A
N
Q
--
G
L
K
-
A
L
E
T
D
D
A
L
A
K
G
L
N
V
Q
-------------------------
10
PsiBlast_PDB
77.52
50%
-109
- C5 -
1SAY
1
?
A:
[1-344]
M
E
I
G
V
P
K
E
I
K
N
Q
E
F
R
V
G
L
S
P
S
S
V
R
T
L
V
E
A
G
H
T
V
F
I
E
T
Q
A
G
I
G
A
G
F
A
D
Q
D
Y
V
Q
A
G
A
Q
V
V
P
S
A
K
D
A
W
S
R
-
E
M
V
V
K
V
K
E
P
L
P
A
-
E
Y
D
L
-----
M
Q
K
D
Q
L
L
F
T
Y
L
H
L
A
A
A
R
E
L
T
E
Q
L
M
R
V
G
L
T
A
I
A
Y
E
T
V
E
L
P
N
R
S
--
L
P
L
L
T
P
M
S
I
I
A
G
R
L
S
V
Q
F
G
A
R
F
L
E
R
Q
Q
G
G
R
G
V
L
L
G
G
V
P
G
V
K
P
G
K
V
V
I
L
G
G
G
V
V
G
T
E
A
A
K
M
A
V
G
L
G
A
Q
V
Q
I
F
D
I
N
V
E
R
L
S
Y
L
E
T
L
F
G
S
R
V
E
L
--------
L
Y
S
N
S
A
E
I
E
T
A
V
A
E
A
D
L
L
I
G
A
V
L
V
P
G
R
R
A
P
I
L
V
P
A
S
L
V
E
Q
M
R
T
G
S
V
I
V
D
V
A
V
D
Q
G
G
C
V
E
T
L
H
P
T
S
H
T
Q
P
T
Y
E
V
F
G
V
V
H
Y
G
V
P
N
M
P
G
A
V
P
W
T
A
T
Q
A
L
N
N
S
T
L
P
Y
V
V
K
L
A
N
Q
--
G
L
K
-
A
L
E
T
D
D
A
L
A
K
G
L
N
V
Q
-------------------------
144
Fugue
59.65
52%
-130
- C5 -
1PJC
1
?
A:
[136-303]
------------------------------------------------------------------------------------------------------------------------------------------------
A
G
R
L
S
V
Q
F
G
A
R
F
L
E
R
Q
Q
G
G
R
G
V
L
L
G
G
V
P
G
V
K
P
G
K
V
V
I
L
G
G
G
V
V
G
T
E
A
A
K
M
A
V
G
L
G
A
Q
V
Q
I
F
D
I
N
V
E
R
L
S
Y
L
E
T
L
F
G
S
R
V
E
L
--------
L
Y
S
N
S
A
E
I
E
T
A
V
A
E
A
D
L
L
I
G
A
V
L
V
P
G
R
R
A
P
I
L
V
P
A
S
L
V
E
Q
M
R
T
G
S
V
I
V
D
V
A
V
D
Q
G
G
C
V
E
T
L
H
P
T
S
H
T
Q
P
T
Y
E
V
F
G
V
V
H
Y
G
V
P
N
M
P
G
A
---------------------------------------------------------------------
142
Fugue
59.65
52%
-130
- C5 -
1PJC
1
?
A:
[136-303]
------------------------------------------------------------------------------------------------------------------------------------------------
A
G
R
L
S
V
Q
F
G
A
R
F
L
E
R
Q
Q
G
G
R
G
V
L
L
G
G
V
P
G
V
K
P
G
K
V
V
I
L
G
G
G
V
V
G
T
E
A
A
K
M
A
V
G
L
G
A
Q
V
Q
I
F
D
I
N
V
E
R
L
S
Y
L
E
T
L
F
G
S
R
V
E
L
--------
L
Y
S
N
S
A
E
I
E
T
A
V
A
E
A
D
L
L
I
G
A
V
L
V
P
G
R
R
A
P
I
L
V
P
A
S
L
V
E
Q
M
R
T
G
S
V
I
V
D
V
A
V
D
Q
G
G
C
V
E
T
L
H
P
T
S
H
T
Q
P
T
Y
E
V
F
G
V
V
H
Y
G
V
P
N
M
P
G
A
---------------------------------------------------------------------
34
PsiBlast_CBE
56.65
31%
-98
- C5 -
1PTJ
3
PNTAA_RHORT
B:
[1-306]
M
K
I
A
I
P
K
E
R
R
P
G
E
D
R
V
A
I
S
P
E
V
V
K
K
L
V
G
L
G
F
E
V
I
V
E
Q
G
A
G
V
G
A
S
I
T
D
D
A
L
T
A
A
G
A
T
I
A
S
T
A
A
Q
A
L
S
Q
A
D
V
V
W
K
V
Q
R
P
M
T
A
-
E
E
G
T
DEVAL
I
K
E
G
A
V
L
M
C
H
L
G
A
L
T
N
R
P
V
V
E
A
L
T
K
R
K
I
T
A
Y
A
M
E
L
M
P
R
I
S
R
A
QS
M
D
I
L
S
S
Q
S
N
L
A
G
Y
R
A
V
I
D
G
A
Y
E
F
A
R
A
F
P
M
M
M
T
A
A
G
T
V
P
---
P
A
R
V
L
V
F
G
V
G
V
A
G
L
Q
A
I
A
T
A
K
R
L
G
A
V
V
M
A
T
D
V
R
A
A
T
K
E
Q
V
E
S
-
L
G
G
K
F
I
T
V
DDEAMEF
R
K
K
Q
A
E
A
V
L
K
E
L
V
K
T
D
I
A
I
T
T
A
L
I
P
G
K
P
A
P
V
L
I
T
E
E
M
V
T
K
M
K
P
G
S
V
I
I
D
L
A
V
E
A
G
G
N
C
P
L
S
E
P
---------------------------------------------------------------------------------------------
35
PsiBlast_CBE
56.54
31%
-99
- C5 -
1NM5
3
PNTAA_RHORT
B:
[1-306]
M
K
I
A
I
P
K
E
R
R
P
G
E
D
R
V
A
I
S
P
E
V
V
K
K
L
V
G
L
G
F
E
V
I
V
E
Q
G
A
G
V
G
A
S
I
T
D
D
A
L
T
A
A
G
A
T
I
A
S
T
A
A
Q
A
L
S
Q
A
D
V
V
W
K
V
Q
R
P
M
T
A
-
E
E
G
T
DEVAL
I
K
E
G
A
V
L
M
C
H
L
G
A
L
T
N
R
P
V
V
E
A
L
T
K
R
K
I
T
A
Y
A
M
E
L
M
P
R
I
S
R
A
NS
M
D
I
L
S
S
Q
S
N
L
A
G
Y
R
A
V
I
D
G
A
Y
E
F
A
R
A
F
P
M
M
M
T
A
A
G
T
V
P
---
P
A
R
V
L
V
F
G
V
G
V
A
G
L
Q
A
I
A
T
A
K
R
L
G
A
V
V
M
A
T
D
V
R
A
A
T
K
E
Q
V
E
S
-
L
G
G
K
F
I
T
VEF-----
R
K
K
Q
A
E
A
V
L
K
E
L
V
K
T
D
I
A
I
T
T
A
L
I
P
G
K
P
A
P
V
L
I
T
E
E
M
V
T
K
M
K
P
G
S
V
I
I
D
L
A
V
E
A
G
G
N
C
P
L
S
E
P
---------------------------------------------------------------------------------------------