@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv2812: (2016-05-13 )
MAVGDDEEKVRAERARAIGLFRYQLIWEAADAAHSTKQRGKMVRELASREHTDPFGRRVRISRQTIDRWIRGWRAGGFDALVPNPRQCTPRTPAEVLELAVALRRENPQRTAAAIRRILRTQLGWAPDERTLQRNFHRLGLTGATTGSAPAVFGRFEAEHPNALWTGDVLHGIRIDLRKTYLFAFLDDHSRLVPGYRWGHAEDTVRLAAALRPALASRGVPNAVYVDNGSPYVDAWLLRACAKLGVRLVHSTPGRPQGRGKIERFFRTVREQFLVEITGEPDVVGRHYVADLAELNRLFTAWVETVYHRSVHSETGQTPLARWSAGGPIPLPAPETLTEAFLWEEHRRVTKTATVSLHGNRYEIDPALVGRKVELVFDPFDLTRIEVRLAGAPMRRAIPYHIGRHSHPKAKPETPTAPPKPSGIDYAQLIETAHAAELARGVNYTALTGAADQIPGQLDLLTGQEAQPK
Atome Classification :
(20 SA)
.........10........20.--........30........40........50...----...--------..60........70..-------......80........90......----..100........110........120........130.......140.-----.....---.150-..---.....160.......170....------...180.......190........200.......210---.......220--..-.....230.---.-----...-.-----------------.240.......250---.-----.......260.......270........--------280-........---------------290.......300....-...310....-.-----...320----.....---..330.......340.......350.--....--------..360..-..--...370-........-.380-.......-390.......400.-......410---.......420.......430.......440.......450.......460.......------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MAVGD
D
E
E
K
V
R
A
E
R
A
R
A
I
G
L
-
F
--
R
Y
Q
L
I
WEAADAA
H
S
T
K
Q
R
G
K
M
V
R
E
L
A
SREHTDP----FG
R
--------
R
V
R
I
S
R
Q
T
I
D
R
W
I
R
G
W
-------RAGGFDALVPNPRQCTPR
T
P
A
E
V
L
----
E
L
A
V
-
A
L
RRE
N
P
Q
R
T
-
A
A
A
I
R
R
I
L
R
-
T
QLGWAP
D
E
R
T
L
Q
R
N
F
H
R
LGLTG-----ATTGS---AP
A
V
-
F
G---RFEAEHPNALW
T
G
D
V
L
H
G
I
R
I
D
------
L
R
K
T
Y
L
F
A
F
LDDHS-RLVPGYRWGH
A
E
D
T
V
R
L
A
A
A
L
R
---
P
A
L
ASRGVP
N
--
A
V
-
Y
VDNGS
P
Y
V
---
D
-----
A
W
L
-
L
-----------------
R
A
C
A
K
L
G
V
R
L
VHS----T-----PGRPQG
R
G
K
I
E
R
F
F
R
T
V
R
-
E
Q
F
L
V
E
ITG--------E-P-DV
V
G
R
H
Y
V
---------------
A
D
L
A
E
L
N
R
L
F
T
A
W
V
E
T
V
-
Y
H
R
S
-VHSET-G-----QTPLAR----WSAGG---PIPLPA
P
E
T
L
T
E
A
F
L
W
E
E
H
RRV
T
K
T
A
--
T
V
S
L--------HG
N
R
Y
EI-
D
P
--
A
LVG---
R
K
V
E
L
V
FD-PFD
L
-
T
R
I
E
V
R
L-AGAP
M
R
RAI
P
Y
HIG-RHSHPKAKP---ETPTAPPKPSGI
D
Y
A
Q
L
I
E
T
A
H
A
A
E
L
ARGVN
Y
T
ALTG
A
A
DQIPGQLDLLTGQEAQPK------------------------------
46
HHSearch
57.46
21%
-85
- C4 -
1CXQ
3
A:
[7-151]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
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---
S
-----
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T
-
R
-----------------
E
W
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A
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W
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A
H
T
T
G
----
I
-----
P
G
----
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N
R
L
L
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-
D
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--------
D
------
G
F
M
K
R
---------------
I
P
T
S
K
Q
G
E
L
L
A
K
A
M
Y
A
--
L
N
H
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
54.72
16%
-70
- C4 -
3OYM
8
POL_FOAMV
A:
[52-276]
-----------------------------------------------------------------------------------------------------------------
P
P
Q
S
D
R
----
Q
K
I
V
-
L
Q
A
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N
L
A
H
T
G
-
R
E
A
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I
A
-
N
L
Y
W
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P
N
M
R
K
D
V
V
K
Q
L
G
R
C
Q
Q
C
L
-----
I
T
N
A
S
NKA
S
G
P
I
-
L
R
---
P
D
R
P
Q
K
P
F
D
K
F
F
I
D
Y
I
G
P
L
P
P
S
------
Q
G
Y
L
Y
V
L
V
V
V
D
G
M
T
-
G
F
T
W
L
Y
P
T
-
K
A
P
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A
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V
K
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L
----
N
V
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I
A
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P
K
--
V
I
-
H
S
D
Q
G
A
A
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---
S
-----
S
T
F
-
A
-----------------
E
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I
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L
E
F
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----
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-----
P
Y
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P
Q
S
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E
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S
D
I
K
-
R
L
L
T
K
L
L
---------------------
V
---------------
G
R
P
T
K
W
Y
D
L
L
P
V
V
Q
L
A
--
L
N
N
T
-
Y
S
P
V
L
-
K
-----
Y
T
P
H
Q
L
----
L
F
G
I
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
HHSearch
53.85
20%
-82
- C4 -
3KKS
2
POL_BIV29
A:
[2-147]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
H
L
W
Q
M
D
N
T
H
W
-----------
N
K
T
I
I
W
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A
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E
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N
S
-
G
L
V
E
A
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I
-
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E
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V
A
L
C
I
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---
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R
Y
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-
L
--
H
L
-
H
S
D
N
G
P
C
F
T
---
A
-----
H
R
I
-
E
-----------------
N
L
C
K
Y
L
G
I
T
K
T
T
G
----
I
-----
P
Y
N
P
Q
S
Q
G
V
V
E
R
A
H
R
D
L
K
-
D
R
L
A
A
Y
Q
-------------------------------------
G
D
C
E
T
V
E
A
A
L
S
L
A
L
V
S
--
L
N
K
K
-
R
G
G
I
G
-
G
-----
H
T
P
Y
E
I
----
Y
L
E
S
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
HHSearch
53.46
16%
-90
- C4 -
4PA1
-
A:
[61-205]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
I
W
Q
M
D
C
T
H
F
-----------
D
G
K
I
I
L
V
G
I
H
V
E
S
-
G
Y
I
W
A
Q
I
I
S
-
Q
E
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A
D
C
T
V
K
A
V
L
---
Q
L
L
S
A
H
N
V
T
---
E
L
-
Q
T
D
N
G
P
N
F
K
---
N
-----
Q
K
M
-
E
-----------------
G
V
L
N
Y
M
G
V
K
H
K
F
G
----
I
-----
P
G
N
P
Q
S
Q
A
L
V
E
N
V
N
H
T
L
K
-
V
W
I
Q
K
F
L
-------------------------------------
P
E
T
T
S
L
D
N
A
L
S
L
A
V
H
S
--
L
N
F
K
-
R
R
G
R
I
G
G
-----
M
A
P
Y
E
L
----
L
A
Q
Q
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
52.55
16%
-17
- C4 -
4QLA
1
HYEP_BOMMO
A:
[19-442]
L
D
L
E
E
W
W
G
P
P
E
L
K
Q
K
Q
D
T
S
I
-
K
--
P
F
E
I
T
F
-------
S
E
T
M
V
K
E
L
K
E
R
I
K
K
R
R
P
F
A
P
PLEG
V
G
F
--------
K
Y
G
F
N
S
K
Q
L
D
S
W
L
K
Y
W
-------
A
E
E
Y
P
F
A
E
R
Q
K
F
L
N
Q
Y
P
H
F
K
T
N
I
Q
----
G
L
N
I
-
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I
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-
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E
I
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L
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W
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G
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E
F
Y
E
A
I
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T
A
V
S
KDRN
F
A
L
E
I
I
---
A
P
S
L
-
P
G
YGF
S
D
A
A
V
R
P
G
-------
L
A
A
A
E
V
A
------
V
I
F
K
N
L
M
A
R
L
G
Y
K
Q
-
Y
Y
V
Q
G
---------
G
D
W
G
A
L
I
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---
S
A
M
A
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E
--
I
I
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LS
P
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-----
A
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-
L
-----------------
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A
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I
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----
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-----
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Y
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----
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-----------
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N
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L
Y
W
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----
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I
--
V
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S
M
--------
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Y
A
E
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F
-
S
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--
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H
F
D
---
L
K
----------
L
-
D
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I
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V
Q
V
-
P
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---
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A
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Q
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---
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G
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A
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K
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E
F
R
K
L
K
N
------------------------------
38
HHSearch
52.09
19%
-81
- C4 -
4FW1
-
POL_RSVP
A:
[54-215]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
L
G
P
L
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I
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T
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F
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E
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M
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A
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A
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----
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W
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P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
HHSearch
51.55
21%
-75
- C4 -
5CZ1
-
?
A:
[55-210]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
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G
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H
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A
A
E
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----
H
W
G
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
51.39
18%
-67
- C4 -
3JCA
5
?
A:
[11-211]
-------------------------------------------------------------------------------------------------------------------------------------
L
H
H
Q
N
-
A
A
A
L
-------
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C
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C
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--------
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----
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-
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---
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A
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--
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N
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-
G
-----
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T
A
A
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R
----
H
W
G
P
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
HHSearch
51.12
17%
-69
- C4 -
3L3U
1
POL_HV1N5
A:
[8-155]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
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Q
V
R
-------------------------------------
D
Q
A
E
H
L
K
T
A
V
Q
M
A
V
F
I
--
H
N
H
K
-
R
K
G
G
I
G
G
-----
Y
S
A
G
E
R
----
I
V
D
I
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
HHSearch
51.08
11%
-61
- C4 -
3F9K
-
POL_HV2RO
A:
[12-205]
--------------------------------------------------------------------------------------------------------------------------------------
E
H
E
K
-
Y
H
S
N
V
K
E
L
S
-
H
K
F
G
I
P
N
L
-
V
-
A
R
Q
I
V
N
S
C
A
Q
C
Q
-----
Q
K
G
E
---------
A
I
---
H
G
Q
V
N
A
E
L
G
T
W
Q
M
D
C
T
H
L
-----------
E
G
K
I
I
I
V
A
V
H
V
A
S
-
G
F
I
E
A
E
V
I
-
P
Q
E
S
G
R
Q
T
A
L
F
L
L
---
K
L
A
S
R
W
P
I
T
---
H
L
-
H
T
D
N
G
A
N
F
T
---
S
-----
Q
E
V
-
K
-----------------
M
V
A
W
W
I
G
I
E
Q
S
F
G
----
V
-----
P
Y
N
P
Q
S
Q
G
V
V
E
A
M
N
H
H
L
K
-
N
Q
I
S
R
I
R
-------------------------------------
E
Q
A
N
T
I
E
T
-
I
V
L
M
A
V
H
C
-
M
N
F
K
-
R
R
G
G
I
G
D
-----
M
T
P
S
E
R
----
L
I
N
M
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
HHSearch
50.17
17%
-70
- C4 -
2X78
-
POL_FOAMV
A:
[119-282]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
K
P
F
D
K
F
F
I
D
Y
I
G
P
L
P
P
S
------
Q
G
Y
L
Y
V
L
V
V
V
D
G
M
T
-
G
F
T
W
L
Y
P
-
T
K
A
P
S
T
S
A
T
V
K
S
L
----
N
V
L
T
S
I
A
I
P
R
--
V
I
-
H
S
D
Q
G
A
A
F
T
---
S
-----
S
T
F
-
A
-----------------
E
W
A
K
E
R
G
I
H
L
E
F
S
----
T
------------
S
K
V
E
R
K
N
S
D
I
K
-
R
L
L
T
K
L
L
V
------------------------------------
G
R
P
T
K
W
Y
D
L
L
P
V
V
Q
L
A
--
L
N
N
T
-
Y
S
P
V
L
-
K
-----
Y
T
P
H
Q
L
----
L
F
G
I
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
HHSearch
49.99
17%
-65
- C4 -
4CF8
12
?
A:
[28-175]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
P
G
I
W
Q
L
D
C
T
H
L
-----------
E
G
K
V
I
L
V
A
V
H
V
A
S
-
G
Y
I
E
A
E
V
I
-
P
A
E
T
G
Q
E
T
A
Y
F
L
L
---
K
L
A
G
R
W
P
-
V
K
--
T
V
-
H
T
D
N
G
S
N
F
T
---
S
-----
T
T
V
-
K
-----------------
A
A
C
W
W
A
G
I
K
Q
E
D
G
----
I
-----
P
Y
N
P
Q
S
Q
G
V
I
E
S
M
N
K
E
L
K
-
K
I
I
G
Q
V
R
-------------------------------------
D
Q
A
E
H
L
K
T
A
V
Q
M
A
V
F
I
--
H
N
H
K
-
R
K
G
---------
Y
S
A
G
E
R
----
I
V
D
I
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
HHSearch
49.98
14%
-70
- C4 -
1K6Y
3
POL_HV1N5
A:
[17-204]
---------------------------------------------------------------------------------------------------------------------------------------------
S
N
W
R
A
M
A
-
S
D
F
N
L
P
-
P
V
-
V
A
K
E
I
V
A
S
C
D
K
C
Q
-----
L
K
---------------------
C
S
P
G
I
W
Q
L
D
C
T
H
L
-----------
E
G
K
V
I
L
V
A
V
H
V
A
S
-
G
Y
I
E
A
E
V
I
-
P
A
E
T
G
Q
E
T
A
Y
F
L
L
---
K
L
A
G
R
W
P
-
V
K
--
T
V
-
H
T
D
N
G
S
N
F
T
---
S
-----
T
T
V
-
K
-----------------
A
A
C
D
W
A
G
I
K
Q
E
D
------------------
G
V
I
E
S
M
N
K
E
L
K
-
K
I
I
G
Q
V
R
-------------------------------------
D
Q
A
E
H
L
K
T
A
V
Q
M
A
V
F
I
--
H
N
K
K
-
R
K
G
G
I
G
G
-----
Y
S
A
G
E
R
----
I
V
D
I
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
49.70
17%
-23
- C4 -
3LM3
3
?
A:
[13-448]
-----
E
P
L
T
I
E
G
N
R
F
V
T
L
C
I
M
I
--
R
T
T
-
P
W
E
V
S
R
---
D
V
K
L
H
P
R
D
E
V
D
W
H
T
L
E
G
V
R
A
----
L
R
E
--------
A
F
A
T
N
N
P
N
G
-
R
L
T
W
G
F
T
M
N
A
L
E
D
G
R
K
N
Y
R
E
I
R
D
Y
V
V
E
C
Q
K
K
Y
G
D
E
V
T
Y
F
PG
Y
F
P
A
M
Y
L
P
R
E
R
V
N
R
E
M
S
E
A
I
E
I
I
S
K
M
V
G
N
G
Y
R
P
------------------------------
Q
S
I
M
G
G
---
F
L
S
A
D
N
L
R
Y
L
A
E
K
E
N
I
H
V
A
H
A
V
------
I
W
S
Q
H
N
G
G
G
A
D
G
-----
S
P
S
Y
P
F
Y
P
S
T
E
-----
H
F
C
K
---
P
A
Q
G
K
S
D
F
I
D
--
C
V
-
N
L
D
---------------
G
W
T
M
D
-----------------
F
I
C
A
R
R
S
G
Q
T
G
H
G
----
I
-----
D
G
Y
N
S
R
R
G
--
V
G
P
I
E
T
Y
K
-
G
W
G
L
D
L
G
H
R
--------
E
-
V
M
H
T
E
A
I
H
F
----------------
D
K
G
L
E
L
N
G
F
--
G
W
V
A
N
I
-
W
E
A
Q
M
V
H
-
E
F
-
G
-----
K
D
L
I
C
D
A
M
K
M
W
V
T
G
T
---
K
E
R
W
P
D
T
H
F
V
T
F
G
E
F
G
E
L
W
R
K
Q
Y
K
S
N
--
D
D
W
N
--------
Y
--
R
F
V
E
-
R
G
--
S
G
L
G
DSY
N
N
L
E
I
K
W
F
M
N
K
E
F
-
R
L
A
L
L
R
D
-
W
H
T
K
N
S
P
A
Y
V
I
D
F
T
-
R
Y
D
L
Q
A
H
E
P
---
A
D
P
S
--
P
E
K
P
A
K
D
W
S
L
I
N
K
I
N
Q
-----
K
A
L
R
P
Q
D
K
P
V
L
I
D
K
L
E
K
E
D
Q
D
L
I
R
K
Y
Y
P
E
L
L-----------------------------
53
HHSearch
49.38
17%
-101
- C4 -
4MQ3
-
A:
[60-166]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
G
I
W
Q
M
D
C
T
H
F
-----------
D
G
K
I
I
L
V
G
I
H
V
E
S
-
G
Y
I
W
A
Q
I
I
-
S
Q
E
T
A
D
C
T
V
K
A
V
L
---
Q
L
L
S
A
H
N
V
T
---
E
L
-
Q
T
D
N
G
P
N
F
K
---
N
-----
Q
K
M
-
E
-----------------
G
V
L
N
Y
M
G
V
K
H
K
F
G
----
I
-----
P
G
N
P
Q
S
Q
A
L
V
E
N
V
N
H
T
L
K
-
V
W
I
Q
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
49.11
19%
-47
- C4 -
1C1A
-
POL_RSVP
A:
[52-272]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
R
G
L
G
P
L
Q
I
W
Q
T
D
F
T
L
E
P
R
M
A
-------
P
R
S
W
L
A
V
T
V
D
T
A
S
-
S
A
I
V
V
T
Q
H
G
R
-
V
T
S
V
A
V
Q
H
H
W
A
---
T
A
I
A
V
L
G
R
P
K
--
A
I
-
K
T
D
N
G
S
C
F
T
---
S
-----
K
S
T
-
R
-----------------
E
W
L
A
R
W
G
I
A
H
T
T
G
----
I
-----
P
G
N
S
Q
G
Q
A
M
V
E
R
A
N
R
L
L
K
-
D
R
I
R
V
L
A
E
G
--------
D
------
G
F
M
K
R
---------------
I
P
T
S
K
Q
G
E
L
L
A
K
A
M
Y
A
L
-
N
H
K
E
-
R
G
E
N
T
-
K
-----
T
P
I
Q
K
H
----
W
R
P
T
V
---
L
T
E
G
P
P
V
K
I
R
I
E
T
G
E
W
E
K
G
W
N
V
L
V
W
G
RG
Y
A
A
V
--------
K
N
R
D
T
D
K
-
V
I
--
W
V
P
S
---
R
K
V
K
P
D
I
T
-
Q
K
-----------------------------------------------------------------------------------------------------------------------------
26
Fugue
48.83
22%
-12
* C5 *
4GA6
3
AMPPA_THEKO
A:
[1-493]
----------
M
K
A
K
I
R
I
L
D
M
-
F
SG
R
Y
T
V
L
I
N
E
E
D
A
K
E
A
K
L
H
P
D
D
L
V
K
I
E
A
G
K
K
A
V
Y
G
----
S
V
A
L
S
NLVGKG
E
V
G
I
S
R
D
V
L
D
--
L
H
N
F
-------
S
E
G
E
T
V
S
V
I
P
A
G
------
T
P
E
S
V
R
----
Y
I
K
K
-
K
M
H
G
E
K
L
R
---
K
V
E
I
E
A
I
V
R
-
D
I
V
D
R
K
L
R
D
I
E
I
S
S
F
V
T
A
L
E
I
N
G
-----
L
D
M
D
E
---
I
A
A
L
-
T
I
---
A
M
A
E
-------
T
G
D
M
L
D
I
D
R
K
P
------
I
--------
M
D
V
H
S
I
G
G
V
P
G
N
K
--
T
N
I
L
V
V
P
I
V
A
A
A
G
LTI
P
K
T
S
S
R
A
I
T
S
--
A
A
G
T
A
D
V
V
E
V
F
A
---
D
VSFS
L
D
E
I
-
K
-----------------
R
I
V
E
K
V
G
A
C
L
V
W
G
----
G
ALNLA
P
A
D
D
I
T
I
K
A
E
R
A
L
S
I
D
P
T
-
G
L
M
L
A
S
I
M
S
--------
K
-
K
-
Y
A
M
G
S
Q
Y
V
L
I
D
I
P
T
G
KGVKVET
V
E
E
A
R
S
L
A
R
D
F
I
E
L
G
K
R
L
G
Q
Y
V
E
-
V
A
I
T
Y
-
G
-----
G
Q
P
I
G
H
----
T
V
--
G
---
P
A
-
L
E
A
R
E
A
L
S
A
L
M
T
G
K
G
P
G
S
L
I
E
K
A
--
T
-
G
L
--------
A
G
I
L
L
E
M
G
G
V
--
A
P
A
G
---
T
G
K
K
M
A
K
E
-
I
L
E
S
------
G
K
-
A
W
E
K
M
K
E
I
I
E
A
Q
G
G
D
P
N
I
K
P
E
E
I
P
IGD
K
T
Y
T
F
T
A
A
T
S
G
--
Y
V
T
A
I
D
N
R
A
I
T
A
I
A
R
A
A
G
A
P
E
D
K
G
A
G
I
E
L
Y
----
V
K
V
G
E
K
V
K
E
G
DPL
F
T
I
H
A
EH
E
A
R
L
D
Q
A
I
V
L
A
R
R
T
EPIRIE
34
HHSearch
48.61
17%
-54
- C4 -
1BCO
-
TNPA_BPMU
A:
[258-560]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
H
L
D
A
M
Q
W
I
N
G
D
G
Y
L
H
N
V
F
V
RWFNG
D
V
I
R
P
K
T
W
F
W
Q
D
V
K
T
-
R
K
I
L
G
W
R
C
D
V
S
E
N
I
D
S
I
R
L
S
F
M
---
D
V
V
T
R
Y
G
I
P
E
D
F
H
I
-
T
I
D
N
T
R
G
A
A
---
N
-----
K
W
L
-
T
GGAPNRYRF
K
V
K
E
D
D
P
K
G
L
F
L
L
M
G
A
K
M
H
W
T
SVVA
G
-----
K
G
W
G
Q
A
K
P
-
V
E
R
A
F
G
V
G
G
L
E
E
Y
V
D
K
H
P
A
LAGAYTGP-------
Y
G
D
R
A
---------------
V
D
A
E
L
F
L
K
T
L
A
E
G
V
A
M
--
F
N
A
R
-
T
G
R
E
T
-
E
MCGGK
L
S
F
D
D
V
----
F
E
R
E
Y
A
R
T
I
V
R
K
P
T
E
E
Q
K
R
M
L
L
L
P
A
E
A
V
N
V
S
R
K
G
--
E
F
T
L
KVGGSLKG
A
K
N
V
Y
Y
N
-
M
A
L
M
N
A
G
V
---
K
K
V
V
V
R
F
D
-
P
Q
Q
L
H
S
T
V
Y
C
Y
T
L
D
G
R
F
I
C
E
A
E
C
L
-------------------------------------------------------------------------------------------------------
39
HHSearch
48.15
17%
-74
- C4 -
1EX4
-
?
A:
[7-155]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
S
P
G
I
W
Q
L
D
C
T
H
L
-----------
E
G
K
V
I
L
V
A
V
H
V
A
S
-
G
Y
I
E
A
E
V
I
-
P
A
E
T
G
Q
E
T
A
Y
F
L
L
---
K
L
A
G
R
W
P
-
V
K
--
T
I
-
H
T
D
N
G
S
N
F
T
---
G
-----
A
T
V
-
R
-----------------
A
A
C
D
W
A
G
I
K
Q
E
D
G
----
I
-----
P
---
Q
S
Q
G
V
V
E
S
M
N
K
E
L
K
-
K
I
I
G
Q
V
R
-------------------------------------
D
Q
A
E
H
L
K
T
A
V
Q
M
A
V
F
I
--
H
N
K
K
-
R
K
G
G
I
G
G
-----
Y
S
A
G
E
R
----
I
V
D
I
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
48.03
17%
-67
- C4 -
4FW2
-
POL_RSVP
A:
[52-215]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
R
G
L
G
P
L
Q
I
W
Q
T
D
F
T
L
E
P
R
-
M
------
A
P
R
S
W
L
A
V
T
V
D
T
A
S
-
S
A
I
V
V
T
Q
-
H
G
R
V
T
S
V
A
V
Q
H
H
W
A
---
T
A
I
A
V
L
G
R
P
K
--
A
I
-
K
T
D
N
G
S
C
F
T
---
S
-----
K
S
T
-
R
-----------------
E
W
L
A
R
W
G
I
A
H
T
T
G
-----------------
A
M
V
E
R
A
N
R
L
L
K
-
D
K
I
R
V
L
A
E
G
--------
D
------
G
F
M
K
R
---------------
I
P
T
S
K
Q
G
E
L
L
A
K
A
M
Y
A
--
L
N
H
K
-
E
R
G
E
N
-
T
-----
K
T
P
I
Q
K
----
H
W
R
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------