@TOME V2.3
(Nov 2016)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv3742c: (2016-05-22 )
MHSEQSASIEHVDVLIVGAGISGTGAAYYLKTMQPAKTFAIVEARYPAIRSDSDLHTFSYEFKPWQHEKATASADAIMVHRGRSLAGGDRTLRHRRTRHHELRMVIIGSGATAVTLVPAMAQTAGAVTMPK
Atome Classification :
(22 SA)
--------------------------------------------------.........10........20........30...--.....40...-----------.-----------..----..50........60-.-----..-----.....70........80-----------------.......-..------------90....-------------------------....----------100.......110.......120.......130-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------------------------------MHSEQSAS
I
E
H
V
D
V
L
I
V
GAGISGTG
A
A
Y
Y
L
KTMQ--PA
K
T
F
A
I
V
E
A-----------R-----------YP----AIRSDSDL
H
T
F
S
Y
E-F-----KP-----WQHEKATASA
D
A
I
M
V
H------------------RGRSLAG-G
D
------------
R
T
L
R
H
R
-------------------------RTR
H
----------
H
E
L
R
M
V
I
IGSG
A
T
A
V
T
L
V
P
A
M
A
QTAGAVTMPK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
73.78
30%
-98
- C5 -
4C77
2
PAMO_THEFY
A:
[15-97]
-----------------------------------------------------------
E
E
V
D
V
L
V
V
G
A
G
F
S
G
L
Y
A
L
Y
R
L
R
E
L
----
G
R
S
V
H
V
I
E
T
AGDVGG
V
W
Y
W
N
R
-----------
Y
P
----
G
A
R
C
D
I
E
S
I
E
Y
C
Y
S
-
F
S
E
E
V
L
Q
E
-----
W
N
W
T
E
R
Y
A
S
Q
P
E
I
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
73.58
30%
-94
- C5 -
2YLS
2
PAMO_THEFY
A:
[15-97]
-----------------------------------------------------------
E
E
V
D
V
L
V
V
G
A
G
F
S
G
L
Y
A
L
Y
R
L
R
E
L
----
G
R
S
V
H
V
I
E
T
AGDVGGVWYWN
R
-----------
Y
P
----
G
A
R
C
D
I
E
S
I
E
Y
C
Y
S
-
F
S
E
E
V
L
Q
E
-----
W
N
W
T
E
R
Y
A
S
Q
P
E
I
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
73.26
30%
-93
- C5 -
2YLR
2
PAMO_THEFY
A:
[15-97]
-----------------------------------------------------------
E
E
V
D
V
L
V
V
G
A
G
F
S
G
L
Y
A
L
Y
R
L
R
E
L
----
G
R
S
V
H
V
I
E
T
AGDVGGVWYWN
R
-----------
Y
P
----
G
A
R
C
D
I
E
S
I
E
Y
C
Y
S
-
F
S
E
E
V
L
Q
E
-----
W
N
W
T
E
R
Y
A
S
Q
P
E
I
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
73.21
30%
-90
- C5 -
4D03
2
PAMO_THEFY
A:
[15-97]
-----------------------------------------------------------
E
E
V
D
V
L
V
V
G
A
G
F
S
G
L
Y
A
L
Y
R
L
R
E
L
----
G
R
S
V
H
V
I
E
T
AGDVGGVWYWN
R
-----------
Y
P
----
G
A
R
D
D
I
E
S
I
E
Y
C
Y
S
-
F
S
E
E
V
L
Q
E
-----
W
N
W
T
E
R
Y
A
S
Q
P
E
I
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
72.94
30%
-86
- C5 -
2YM1
3
PAMO_THEFY
A:
[15-98]
-----------------------------------------------------------
E
E
V
D
V
L
V
V
G
A
G
F
S
G
L
Y
A
L
Y
R
L
R
E
L
----
G
R
S
V
H
V
I
E
T
AGDVGGVWYWN
R
-----------
Y
P
----
G
A
R
C
D
I
E
S
I
E
Y
C
Y
S
-
F
S
E
E
V
L
Q
E
-----
W
N
W
T
E
R
Y
A
S
Q
P
E
I
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
72.81
30%
-82
- C5 -
4D04
2
PAMO_THEFY
A:
[15-97]
-----------------------------------------------------------
E
E
V
D
V
L
V
V
G
A
G
F
S
G
L
Y
A
L
Y
R
L
R
E
L
----
G
R
S
V
H
V
I
E
T
AGDVGGVWYWN
R
-----------
Y
P
----
G
A
R
D
D
I
E
S
I
E
Y
C
Y
S
-
F
S
E
E
V
L
Q
E
-----
W
N
W
T
E
R
Y
A
S
Q
P
E
I
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
72.72
30%
-85
- C5 -
4C74
2
PAMO_THEFY
A:
[15-97]
-----------------------------------------------------------
E
E
V
D
V
L
V
V
G
A
G
F
S
G
L
Y
A
L
Y
R
L
R
E
L
----
G
R
S
V
H
V
I
E
T
AGDVGGVWYWN
R
-----------
Y
P
----
G
A
R
C
D
I
E
S
I
E
Y
C
Y
S
-
F
S
E
E
V
L
Q
E
-----
W
N
W
T
E
R
Y
A
S
Q
P
E
I
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
72.46
30%
-90
- C5 -
2YLT
2
PAMO_THEFY
A:
[15-97]
-----------------------------------------------------------
E
E
V
D
V
L
V
V
G
A
G
F
S
G
L
Y
A
L
Y
R
L
R
E
L
----
G
R
S
V
H
V
I
E
T
AGDVGGVWYWN
R
-----------
Y
P
----
G
A
R
C
D
I
E
S
I
E
Y
C
Y
S
-
F
S
E
E
V
L
Q
E
-----
W
N
W
T
E
R
Y
A
S
Q
P
E
I
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
72.28
30%
-87
- C5 -
2YLW
3
PAMO_THEFY
A:
[15-97]
-----------------------------------------------------------
E
E
V
D
V
L
V
V
G
A
G
F
S
G
L
Y
A
L
Y
R
L
R
E
L
----
G
R
S
V
H
V
I
E
T
AGDVGGVWYWN
R
-----------
Y
P
----
G
A
R
C
D
I
E
S
I
E
Y
C
Y
S
-
F
S
E
E
V
L
Q
E
-----
W
N
W
T
E
R
Y
A
S
Q
P
E
I
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
72.03
30%
-89
- C5 -
4OVI
3
PAMO_THEFY
A:
[15-97]
-----------------------------------------------------------
E
E
V
D
V
L
V
V
G
A
G
F
S
G
L
Y
A
L
Y
R
L
R
E
L
----
G
R
S
V
H
V
I
E
T
AGDVGGVWYWN
R
-----------
Y
P
----
G
A
R
C
D
I
E
S
I
E
Y
C
Y
S
-
F
S
E
E
V
L
Q
E
-----
W
N
W
T
E
R
Y
A
S
Q
P
E
I
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
71.89
30%
-91
- C5 -
1W4X
1
PAMO_THEFY
A:
[15-97]
-----------------------------------------------------------
E
E
V
D
V
L
V
V
G
A
G
F
S
G
L
Y
A
L
Y
R
L
R
E
L
----
G
R
S
V
H
V
I
E
T
AGDVGG
V
W
Y
W
N
R
-----------
Y
P
----
G
A
R
C
D
I
E
S
I
E
Y
C
Y
S
-
F
S
E
E
V
L
Q
E
-----
W
N
W
T
E
R
Y
A
S
Q
P
E
I
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
131
HHSearch
71.87
22%
-91
- C5 -
4RG3
4
?
A:
[14-215]
----------------------------------------------------------
T
H
T
V
D
A
V
V
I
G
A
G
F
G
G
I
Y
A
V
H
K
L
H
H
E
L
---
G
L
T
T
V
G
F
D
K
-----------
A
DGPGGTWYWNR
Y
P
----
G
A
L
S
D
T
E
S
H
L
Y
R
F
S
-
F
-----
D
R
D
L
L
Q
E
S
T
W
K
T
T
Y
I
T
Q
P
E
I
L
E
Y
L
E
D
V
V
D
R
F
DLRRHFKFGT
E
V
T
S
A
L
Y
-
L
D
DEN
L
W
E
V
T
T
DHG
E
V
Y
R
A
K
Y
V
V
N
AVGLLSA
I
N
F
P
N
L
PGLDTFE
G
E
T
I
H
TAAWPEGKSL
A
G
R
R
V
G
V
I
G
T
G
S
T
G
Q
Q
V
I
T
S
L
A
P
E
V
E
H
L
T
V
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
126
Fugue
71.70
30%
-68
- C5 -
4UIR
3
OLHYD_ELIME
A:
[2-646]
NPITSKF
D
K
V
L
N
A
SSEYGHVNHEPDSSKEQ
Q
R
N
T
PQKSMPFSDQIGNYQR
N
K
G
I
P
V
Q
S
Y
D
N
S
K
I
Y
I
I
G
S
G
I
A
G
M
S
A
A
Y
Y
F
I
R
D
G
HV
P
A
K
N
I
T
F
L
E
Q
-----------
L
-----------
H
I
------------------------------------------------------------------
D
G
G
S
L
D
G
A
G
N
------------
P
T
D
G
Y
I
-------------------------
I
R
G
G
----------
R
E
M
D
M
T
Y
--------
E
N
L
W
D
M
F
Q
D
I
P
A
L
E
M
P
A
PYS
V
L
D
E
Y
R
L
I
N
D
N
D
S
N
Y
S
KARLINNK
G
E
I
K
DFSKFGLN
K
M
D
Q
L
A
I
I
R
L
L
L
KNKEELDDLTIEDYFS
E
S
F
L
K
S
N
F
W
T
F
W
R
T
M
F
AFENWHS
L
L
E
L
K
L
Y
M
H
R
F
L
HAIDGLNDLSS
L
V
F
P
KYNQYDTF
V
T
P
L
R
K
F
L
Q
E
K
G
V
N
I
H
L
NTLVK
D
L
D
I
H
I
N
TE
G
K
V
V
E
G
I
I
T
EQDG
K
E
V
K
I
P
V
G
KN
D
Y
V
I
V
TTGSMTED
T
F
Y
G
NNKTAPIIGIDNSTSGQSA
G
W
K
L
W
K
N
L
A
A
K
SEIFGKPEKFCSNIEKS
A
W
E
S
A
T
L
TCKPS
A
L
I
D
K
L
K
E
Y
SVNDPYSGKTVTG
G
I
I
T
ITDSNWL
M
S
F
T
C
N
RQPHFPEQPDD
V
L
V
L
W
V
Y
A
LFMDKEGNYIKKTMLECT
G
D
E
I
L
A
E
L
C
Y
H
L
GIEDQ
L
E
N
V
Q
K
N
T
I
V
R
T
A
F
M
PYITSMFMPRAKGD
R
P
R
VVPEGCKN
L
G
L
V
G
QFVETN
N
D
V
V
FT
M
E
S
S
V
R
T
A
R
I
A
V
Y
K
L
L
NLN
K
Q
V
P
D
I
NPLQYD
I
R
H
L
L
K
A
A
K
T
L
N
DDKPFVG
E
G
L
L
R
K
V
LKGTYFEHVLPAGEEHESF
I
A
E
H
V
N
K
F
R
E
W
V
K
G
IRG
1
PsiBlast_PDB
71.51
30%
-84
- C5 -
2YLZ
1
PAMO_THEFY
A:
[15-97]
-----------------------------------------------------------
E
E
V
D
V
L
V
V
G
A
G
F
S
G
L
Y
A
L
Y
R
L
R
E
L
----
G
R
S
V
H
V
I
E
T
AGDVGGVWYWN
R
-----------
Y
P
----
G
A
R
C
D
I
E
S
I
E
Y
C
Y
S
-
F
S
E
E
V
L
Q
E
-----
W
N
W
T
E
R
Y
A
S
Q
P
E
I
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
70.70
30%
-86
- C5 -
2YM2
2
PAMO_THEFY
A:
[15-98]
-----------------------------------------------------------
E
E
V
D
V
L
V
V
G
A
G
F
S
G
L
Y
A
L
Y
R
L
R
E
L
----
G
R
S
V
H
V
I
E
T
AGDVGG
V
W
Y
W
N
R
-----------
Y
P
----
G
A
R
C
D
I
E
S
I
E
Y
C
Y
S
-
F
S
E
E
V
L
Q
E
-----
W
N
W
T
E
R
Y
A
S
Q
P
E
I
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
70.20
32%
-92
- C5 -
2YLX
2
PAMO_THEFY
A:
[15-97]
-----------------------------------------------------------
E
E
V
D
V
L
V
V
G
A
G
F
S
G
L
Y
A
L
Y
R
L
R
E
L
----
G
R
S
V
H
V
I
E
T
AGDVGGVWYWN
R
-----------
Y
P
GARC
A
I
E
S
I
E
Y
C
Y
S
F
S
E
E
V
L
-----
Q
E
-----
W
N
W
T
E
R
Y
A
S
Q
P
E
I
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
63.21
28%
-64
- C5 -
4AP3
2
?
A:
[23-113]
--------------------------------------------------------------
D
V
V
V
V
G
A
G
I
A
G
L
Y
A
I
H
R
F
R
S
Q
----
G
L
T
V
R
A
F
E
A
ASGVGGVWYWN
R
-----------
Y
P
----
G
A
R
C
D
V
E
S
I
D
Y
S
Y
S
-
F
-----
S
P
E
L
E
Q
E
W
N
W
S
E
K
Y
A
T
Q
P
E
I
L
A
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
62.23
28%
-65
- C5 -
4AOX
1
?
A:
[23-112]
--------------------------------------------------------------
D
V
V
V
V
G
A
G
I
A
G
L
Y
A
I
H
R
F
R
S
Q
----
G
L
T
V
R
A
F
E
A
ASGVGGVWYWN
R
-----------
Y
P
----
G
A
R
C
D
V
E
S
I
D
Y
S
Y
S
-
F
-----
S
P
E
L
E
Q
E
W
N
W
S
E
K
Y
A
T
Q
P
E
I
L
A
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
61.62
28%
-63
- C5 -
4AOS
2
?
A:
[23-111]
--------------------------------------------------------------
D
V
V
V
V
G
A
G
I
A
G
L
Y
A
I
H
R
F
R
S
Q
----
G
L
T
V
R
A
F
E
A
ASGVGGVWYWN
R
-----------
Y
P
----
G
A
R
C
D
V
E
S
I
D
Y
S
Y
S
-
F
-----
S
P
E
L
E
Q
E
W
N
W
S
E
K
Y
A
T
Q
P
E
I
L
A
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
61.25
28%
-59
- C5 -
4AP1
2
?
A:
[23-111]
--------------------------------------------------------------
D
V
V
V
V
G
A
G
I
A
G
L
Y
A
I
H
R
F
R
S
Q
----
G
L
T
V
R
A
F
E
A
ASGVGGVWYWN
R
-----------
Y
P
----
G
A
R
C
D
V
E
S
I
D
Y
S
Y
S
-
F
-----
S
P
E
L
E
Q
E
W
N
W
S
E
K
Y
A
T
Q
P
E
I
L
A
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
132
HHSearch
55.06
39%
-101
- C5 -
1W4X
1
PAMO_THEFY
A:
[10-47]
------------------------------------------------------
R
R
Q
P
P
E
E
V
D
V
L
V
V
G
A
G
F
S
G
L
Y
A
L
Y
R
L
R
E
L
----
G
R
S
V
H
V
I
E
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
134
HHSearch
45.72
32%
-68
* C5 *
4AP3
1
?
A:
[20-61]
-----------------------------------------------------------
T
S
Y
D
V
V
V
V
G
A
G
I
A
G
L
Y
A
I
H
R
F
R
S
Q
----
G
L
T
V
R
A
F
E
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------