@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv3764c: (2016-05-23 )
MGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFLDAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLGRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALAPLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSARQASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLVEDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQPLESSPR
Atome Classification :
(22 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240--------------------------------------------------------------------------------------------------------------...----......250.......260....-...270...-...--..280.......290.......300.......310..-......320......----.330.......340-----....--.--.--.---.------------.350.......360.......370...---....---380.......390..--.....400.......410.......420.......430.......440.......450.-.-.-....460..--.....470...
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MGI
T
A
A
T
E
M
A
L
R
R
H
L
V
A
Q
L
D
N
QLGG
T
S
Y
R
S
VLMYPEKMPRPPWR
H
E
T
H
N
Y
I
RSGPGPRFLDAPGQPA
G
M
V
A
A
V
VSDG
T
T
V
A
A
G
Y
L
TGSGSR
A
A
LTST
G
R
S
Q
L
E
R
I
AGSRT
P
L
T
L
DLDGLG
R
Y
R
V
L
AAPSRNG
H
D
V
I
V
T
GLSMGN
V
D
A
T
M
L
Q
M
L
I
I
F
G
I
V
T
V
I
A
L
V
A
A
TT
A
G
I
V
I
I
K
R
A
L
A
P
L
R
R
V
A
Q
T
A
S
E
V
VDLPLDRG
E
V
K
L
P
V
RVPEPDANPST
E
V
G
Q
L
G
S
A
L
N
R
M
L
D
H
I
A
A
A
L
S
AR----------------------------------------------------------------------------------------------------------------
Q
A
S
----
E
T
C
V
R
Q
F
V
A
DA
S
H
E
L
R
T
P
L
A
A
I
R
-
G
Y
T
E
-
L
T
Q
R-IGD--
D
P
E
A
V
A
H
A
M
S
R
V
A
S
E
T
E
R
I
T
R
L
V
E
D
L
L
L
L
A
RLD-SGR-PLERGPV
D
M
S
R
L
A
V
D
----AVSDAHVAGPDH-------
Q
W
AL--D--L--P---P------------E
P
V
V
IPG
D
A
A
R
L
H
Q
V
V
T
N
L
L
AN
A
R
VHT---GPG
T
---
I
V
T
T
RLSTGP
T
H
V
V
L
--
Q
V
IDNGPGI
P
A
A
L
Q
S
E
V
F
E
R
F
ARGDTSRSRQAGST
G
L
G
L
A
I
V
S
A
V
V
K
AHN
G
T
I
T
VSSSP-G-Y-
T
E
F
A
V
RLPL--DGWQPLESSPR
51
HHSearch
78.40
32%
-121
- C- -
2C2A
2
?
A:
[18-250]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
M
K
T
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
A
I
K
-
A
Y
A
E
-
T
I
Y
N
-
S
L
G
EL
D
L
S
T
L
K
E
F
L
E
V
I
I
D
Q
S
N
H
L
E
N
L
L
N
E
L
L
D
F
S
R
L
E
-
R
K
S
L
Q
I
N
R
E
K
V
D
L
C
D
L
V
E
S
----
A
V
N
A
I
K
E
F
A
S
S
H
-------
N
V
N
V
--
L
F
E
S
--
N
V--
P
------------
C
P
V
E
A
Y
I
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
K
Y
S
---
K
K
D
A
P
D
K
Y
V
K
V
I
L
D
E
K
D
G
G
V
L
I
--
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
---------
T
G
L
G
L
A
I
T
K
E
I
V
E
L
H
G
G
R
I
W
V
E
S
E
V
-
G
K
G
-
S
R
F
F
V
W
I
P
K
--
D
R
A
--------
47
HHSearch
76.30
33%
-98
- C2 -
4U7O
1
?
A:
[32-263]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
N
D
R
K
Q
F
V
S
N
V
S
H
E
L
R
T
P
L
T
S
L
R
-
S
Y
I
E
-
A
L
S
D
-
G
A
W
K-
D
P
E
V
A
P
G
F
L
K
V
T
Q
E
E
T
D
R
M
I
R
M
I
N
E
L
L
S
L
S
R
M
D
-
S
G
T
T
R
V
D
M
E
L
V
N
I
N
E
M
F
N
Y
----
V
L
D
R
F
D
M
I
L
K
K
D
DNPA
K
Y
Y
T
I
K
R
--
E
--
F
--
T
---
K
------------
R
D
L
W
V
E
I
D
T
D
K
F
T
Q
V
L
D
N
I
M
N
N
A
I
K
Y
S
---
P
D
G
G
---
V
V
T
C
R
L
L
E
T
H
N
Q
V
I
I
--
S
I
S
D
Q
G
L
G
I
P
R
A
D
L
G
H
V
F
D
R
F
F
R
V
D
K
-----
Q
G
G
T
G
L
G
L
A
I
S
K
E
V
V
Q
M
L
G
G
R
I
W
V
D
S
V
E
-
G
-
K
G
S
T
F
Y
I
S
L
P
Y
--
E
----------
15
PsiBlast_PDB
73.60
32%
-97
- C2 -
4JAV
6
?
A:
[22-248]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
A
I
K
-
A
Y
A
E
T
I
Y
N
S
-
L
G
E
L-
D
L
S
T
L
K
E
F
L
E
V
I
I
D
Q
S
N
H
L
E
N
L
L
N
E
L
L
D
F
S
R
L
E
R
K
S
L
-
Q
I
N
R
E
K
V
D
L
C
D
L
V
E
S
----
A
V
N
A
I
K
E
F
A
S
S
H
-------
N
V
N
V
--
L
--
F
--
E
S
NV
P
------------
C
P
V
E
A
Y
I
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
K
Y
S
KKD
A
P
D
K
---
Y
V
K
V
I
L
D
E
K
D
G
G
V
L
I
--
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
S
S
L
T
Y
E
V
P
G
T
G
L
G
L
A
I
T
K
E
I
V
E
L
H
G
G
R
I
W
V
E
S
E
V
-
G
-
K
G
S
R
F
F
V
W
I
P
K
--
D
----------
13
PsiBlast_PDB
73.47
32%
-106
- C2 -
2C2A
2
?
A:
[22-248]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
A
I
K
-
A
Y
A
E
T
I
Y
N
S
-
L
G
E
L-
D
L
S
T
L
K
E
F
L
E
V
I
I
D
Q
S
N
H
L
E
N
L
L
N
E
L
L
D
F
S
R
L
E
R
K
S
L
-
Q
I
N
R
E
K
V
D
L
C
D
L
V
E
S
----
A
V
N
A
I
K
E
F
A
S
S
H
-------
N
V
N
V
--
L
--
F
--
E
S
NV
P
------------
C
P
V
E
A
Y
I
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
K
Y
S
KKD
A
P
D
K
---
Y
V
K
V
I
L
D
E
K
D
G
G
V
L
I
--
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
---------
T
G
L
G
L
A
I
T
K
E
I
V
E
L
H
G
G
R
I
W
V
E
S
E
V
-
G
-
K
G
S
R
F
F
V
W
I
P
K
--
D
----------
12
PsiBlast_PDB
73.19
32%
-103
- C2 -
4JAU
1
?
A:
[22-247]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
V
I
K
-
G
Y
A
E
-
M
I
Y
N
S
L
G
E
L-
D
L
S
T
L
K
E
F
L
E
T
I
I
E
Q
S
N
H
L
E
N
L
L
N
E
L
L
D
F
S
R
L
E
R
K
S
L
-
Q
I
N
R
E
K
V
D
L
C
D
L
V
E
S
----
A
V
N
A
I
K
E
F
A
S
S
H
-------
N
V
N
V
--
L
--
F
--
E
S
NV
P
------------
C
P
V
E
A
Y
I
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
K
Y
S
KKD
A
P
D
K
---
Y
V
K
V
I
L
D
E
K
D
G
G
V
L
I
--
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
S
---------
G
L
G
L
A
I
T
K
E
I
V
E
L
H
G
G
R
I
W
V
E
S
E
V
-
G
-
K
G
S
R
F
F
V
W
I
P
K
-------------
11
PsiBlast_PDB
71.22
32%
-92
- C2 -
4JAS
2
?
A:
[22-248]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
V
I
K
-
G
Y
A
E
-
M
I
Y
N
S
L
G
E
L-
D
L
S
T
L
K
E
F
L
E
T
I
I
E
Q
S
N
H
L
E
N
L
L
N
E
L
L
D
F
S
R
L
E
R
K
S
L
-
Q
I
N
R
E
K
V
D
L
C
D
L
V
E
S
----
A
V
N
A
I
K
E
F
A
S
S
H
-------
N
V
N
V
--
L
--
F
--
E
S
NV
P
------------
C
P
V
E
A
Y
I
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
K
Y
S
KKD
A
P
D
K
---
Y
V
K
V
I
L
D
E
K
D
G
G
V
L
I
--
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
S
S
L
T
Y
E
V
P
G
T
G
L
G
L
A
I
T
K
E
I
V
E
L
H
G
G
R
I
W
V
E
S
E
V
-
G
-
K
G
S
R
F
F
V
W
I
P
K
--
D
----------
22
PsiBlast_CBE
71.11
32%
-96
- C2 -
4JAV
6
?
B:
[22-248]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
A
I
K
-
A
Y
A
E
T
I
Y
N
S
-
L
G
E
L-
D
L
S
T
L
K
E
F
L
E
V
I
I
D
Q
S
N
H
L
E
N
L
L
N
E
L
L
D
F
S
R
L
E
R
K
S
L
-
Q
I
N
R
E
K
V
D
L
C
D
L
V
E
S
----
A
V
N
A
I
K
E
F
A
S
S
H
-------
N
V
N
V
--
L
--
F
--
E
S
NV
P
------------
C
P
V
E
A
Y
I
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
K
Y
S
KKD
A
P
D
K
---
Y
V
K
V
I
L
D
E
K
D
G
G
V
L
I
--
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
S
S
L
T
Y
E
V
P
G
T
G
L
G
L
A
I
T
K
E
I
V
E
L
H
G
G
R
I
W
V
E
S
E
V
-
G
-
K
G
S
R
F
F
V
W
I
P
K
--
D
----------
23
PsiBlast_CBE
70.65
32%
-94
- C2 -
3DGE
2
?
B:
[22-248]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
A
I
K
-
A
Y
A
E
T
I
Y
N
S
-
L
G
E
L-
D
L
S
T
L
K
E
F
L
E
V
I
I
D
Q
S
N
H
L
E
N
L
L
N
E
L
L
D
F
S
R
L
E
R
K
S
L
-
Q
I
N
R
E
K
V
D
L
C
D
L
V
E
S
----
A
V
N
A
I
K
E
F
A
S
S
H
-------
N
V
N
V
--
L
--
F
--
E
SNV
P
------------
C
P
V
E
A
Y
I
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
K
Y
S
KKD
A
P
D
K
---
Y
V
K
V
I
L
D
E
K
D
G
G
V
L
I
--
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
S
S
L
T
Y
E
V
P
G
T
G
L
G
L
A
I
T
K
E
I
V
E
L
H
G
G
R
I
W
V
E
S
E
V
-
G
-
K
G
S
R
F
F
V
W
I
P
K
--
D
----------
14
PsiBlast_PDB
70.36
32%
-93
- C2 -
3DGE
3
?
A:
[22-248]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
A
I
K
-
A
Y
A
E
T
I
Y
N
S
-
L
G
E
L-
D
L
S
T
L
K
E
F
L
E
V
I
I
D
Q
S
N
H
L
E
N
L
L
N
E
L
L
D
F
S
R
L
E
R
K
S
L
-
Q
I
N
R
E
K
V
D
L
C
D
L
V
E
S
----
A
V
N
A
I
K
E
F
A
S
S
H
-------
N
V
N
V
--
L
--
F
--
E
S
NV
P
------------
C
P
V
E
A
Y
I
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
K
Y
S
KKD
A
P
D
K
---
Y
V
K
V
I
L
D
E
K
D
G
G
V
L
I
--
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
S
S
L
T
Y
E
V
P
G
T
G
L
G
L
A
I
T
K
E
I
V
E
L
H
G
G
R
I
W
V
E
S
E
V
-
G
-
K
G
S
R
F
F
V
W
I
P
K
--
D
----------
2
PsiBlast_PDB
69.93
33%
-99
- C2 -
4U7O
1
?
A:
[25-263]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
E
Q
----------------------------------------------------------------------------------------------------------------
Q
K
I
----
D
N
D
R
K
Q
F
V
S
N
V
S
H
E
L
R
T
P
L
T
S
L
R
-
S
Y
I
E
A
L
S
D
G
-
A
W
K
--
D
P
E
V
A
P
G
F
L
K
V
T
Q
E
E
T
D
R
M
I
R
M
I
N
E
L
L
S
L
S
R
M
D
-
S
G
T
-
T
----
R
V
D
M
E
L
V
N
I
N
----
E
M
F
N
Y
V
L
D
R
F
D
M
-------
I
L
K
K
--
D
--
D
--
N
---
P
A
K
Y
Y
T
I
K
R
E
F
T
K
R
D
L
W
V
E
I
D
T
D
K
F
T
Q
V
L
D
N
I
M
N
N
A
I
K
Y
S
---
P
D
G
G
---
V
V
T
C
R
L
L
E
T
H
N
Q
V
I
I
--
S
I
S
D
Q
G
L
G
I
P
R
A
D
L
G
H
V
F
D
R
F
F
R
V
D
K
-----
Q
G
G
T
G
L
G
L
A
I
S
K
E
V
V
Q
M
L
G
G
R
I
W
V
D
S
V
E
-
G
-
K
G
S
T
F
Y
I
S
L
P
-----
Y
E
-------
40
HHSearch
68.46
26%
-75
- C2 -
4I5S
-
?
A:
[37-432]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
N
N
Q
V
K
Q
L
N
A
K
V
R
S
L
I
T
G
H
Y
-------
T
D
K
L
K
V
E
---
D
N
S
D
L
S
E
L
V
N
N
V
N
D
L
S
E
V
F
R
L
T
H
E
N
L
A
Q
E
K
N
R
L
T
S
I
L
S
YMT
D
G
V
L
A
T
D
RSGKITVIN
D
M
A
Q
K
Q
L
NVTREQALECNILDILDDDSY
T
Y
N
D
L
I
TK
T
P
E
I
V
L
T
RRDEYD
E
F
I
T
L
R
I
R
F
A
L
NRRESGFIS
G
L
I
A
V
L
H
DA
T
E
Q
E
K
E
----
E
R
E
R
R
L
F
V
S
N
V
S
H
E
L
R
T
P
L
T
S
V
K
-
S
Y
L
E
-
A
L
D
D
-
G
A
L
--
T
E
S
V
A
P
S
F
I
K
V
S
L
D
E
T
N
R
M
M
R
M
I
T
D
L
L
S
L
S
R
------S
H
L
D
V
E
L
T
N
F
T
A
F
M
N
Y
----
I
L
D
R
F
D
Q
I
Q
S
Q
Q
ST-------
E
I
I
R
D
--
Y
--
P
---
D
------------
K
S
V
W
I
E
I
D
T
D
K
M
T
Q
V
I
D
N
I
L
N
N
A
I
K
Y
S
---
P
D
G
G
---
K
V
T
I
T
M
Q
T
T
D
T
Q
L
I
L
--
S
I
S
D
Q
G
L
G
I
P
K
K
D
L
P
L
I
F
D
R
F
Y
R
V
D
K
A
R
-------
G
L
G
L
A
I
A
K
E
I
V
K
Q
H
K
G
F
I
W
A
N
S
E
E
-
G
E
G
-
S
T
F
T
I
V
L
P
--------------
48
HHSearch
67.89
34%
-97
- C2 -
4Q20
-
DIVL_CAUCR
A:
[537-758]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
----
E
R
L
K
R
D
F
V
G
N
V
S
Y
E
L
R
T
P
L
T
T
I
I
-
G
Y
S
E
-
L
L
E
R
-
A
D
----
S
E
R
G
R
N
H
V
A
A
V
R
A
A
A
T
Q
L
A
R
S
I
D
D
V
L
D
M
A
Q
I
D
-
A
G
E
M
A
L
E
I
E
D
I
R
V
S
D
L
L
L
N
----
A
Q
E
R
A
L
K
D
A
Q
L
G
-------
G
V
T
L
--
A
--
V
E
C
E
---
E
------------
D
V
G
L
I
R
G
D
G
K
R
L
A
Q
T
L
D
H
L
V
E
N
A
L
R
Q
T
---
P
P
G
G
---
R
V
T
L
S
A
R
R
A
L
G
E
V
R
L
--
D
V
S
D
T
G
R
G
V
P
F
H
V
Q
A
H
I
F
D
R
F
V
G
R
D
R
------
G
G
P
G
L
G
L
A
L
V
K
A
L
V
E
L
H
G
G
W
V
A
L
E
S
E
P
-
G
N
G
-
S
T
F
T
C
H
L
P
E
--
T
Q
---------
4
PsiBlast_PDB
66.68
33%
-94
- C2 -
4Q20
-
DIVL_CAUCR
A:
[526-755]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
A
D
R
----------------------------------------------------------------------------------------------------------------
S
A
A
L
A
E
A
E
R
L
K
R
D
F
V
G
N
V
S
Y
E
L
R
T
P
L
T
T
I
I
-
G
Y
S
E
-
L
L
E
R
-
A
D
----
S
E
R
G
R
N
H
V
A
A
V
R
A
A
A
T
Q
L
A
R
S
I
D
D
V
L
D
M
A
Q
I
D
-
A
G
E
M
A
L
E
I
E
D
I
R
V
S
D
L
L
L
N
A
Q
E
R
A
L
K
D
A
Q
L
G
G
V
---------
T
L
A
V
--
E
--
C
--
E
---
E
------------
D
V
G
L
I
R
G
D
G
K
R
L
A
Q
T
L
D
H
L
V
E
N
A
L
R
Q
T
---
P
P
G
G
---
R
V
T
L
S
A
R
R
A
L
G
E
V
R
L
--
D
V
S
D
T
G
R
G
V
P
F
H
V
Q
A
H
I
F
D
R
F
V
------
G
R
D
R
G
G
P
G
L
G
L
A
L
V
K
A
L
V
E
L
H
G
G
W
V
A
L
E
S
E
P
-
G
-
N
G
S
T
F
T
C
H
L
P
--------------
7
PsiBlast_PDB
64.64
26%
-97
- C2 -
4BIY
3
CPXA_ECOLI
A:
[61-294]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
G
A
S
F
N
Q
V
V
T
A
L
E
R
M
M
T
S
Q
----------------------------------------------------------------------------------------------------------------
Q
-----------
R
L
L
S
D
I
S
H
E
L
R
T
P
L
T
R
L
Q
L
G
T
A
L
-
L
R
R
R
-
S
G
E
--
S
K
E
-----
L
E
R
I
E
T
E
A
Q
R
L
D
S
M
I
N
D
L
L
V
M
S
R
N
Q
-
Q
K
N
-
A
L
V
S
E
T
I
K
A
N
Q
L
W
S
E
----
V
L
D
N
A
A
F
E
A
E
Q
M
-------
G
K
S
L
T
V
N
--
F
--
P
---
P
------------
G
P
W
P
L
Y
G
N
P
N
A
L
E
S
A
L
E
N
I
V
R
N
A
L
R
Y
S
---
H
--
T
---
K
I
E
V
G
F
A
V
D
K
D
G
I
T
I
--
T
V
D
D
D
G
P
G
V
S
P
E
D
R
E
Q
I
F
R
P
F
Y
R
T
D
---------
T
G
L
G
L
A
I
V
E
T
A
I
Q
Q
H
R
G
W
V
K
A
E
D
S
P
L
G
-
G
-
L
R
L
V
I
W
L
P
L
-------------
6
PsiBlast_PDB
64.53
26%
-98
- C2 -
4BIX
3
CPXA_ECOLI
A:
[61-294]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
G
A
S
F
N
Q
V
V
T
A
L
E
R
M
M
T
S
Q
----------------------------------------------------------------------------------------------------------------
Q
-----------
R
L
L
S
D
I
S
H
E
L
R
T
P
L
T
R
L
Q
L
G
T
A
L
-
L
R
R
R
-
S
G
E
--
S
K
E
-----
L
E
R
I
E
T
E
A
Q
R
L
D
S
M
I
N
D
L
L
V
M
S
R
N
Q
-
Q
K
N
-
A
L
V
S
E
T
I
K
A
N
Q
L
W
S
E
----
V
L
D
N
A
A
F
E
A
E
Q
M
-------
G
K
S
L
T
V
N
--
F
--
P
---
P
------------
G
P
W
P
L
Y
G
N
P
N
A
L
E
S
A
L
E
N
I
V
R
N
A
L
R
Y
S
---
H
--
T
---
K
I
E
V
G
F
A
V
D
K
D
G
I
T
I
--
T
V
D
D
D
G
P
G
V
S
P
E
D
R
E
Q
I
F
R
P
F
Y
R
T
D
--------
G
T
G
L
G
L
A
I
V
E
T
A
I
Q
Q
H
R
G
W
V
K
A
E
D
S
P
L
G
-
G
-
L
R
L
V
I
W
L
P
L
-------------
9
PsiBlast_PDB
64.23
26%
-79
- C2 -
4BIV
2
CPXA_ECOLI
A:
[30-294]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
A
R
K
L
K
N
A
A
D
E
V
A
-----
Q
G
N
L
R
---
Q
H
P
E
L
E
A
G
P
Q
-
E
F
L
A
A
G
A
S
F
N
Q
M
V
-------
T
A
L
----------------------------------------------------------------------------------------------------------------
E
R
M
----
M
T
S
Q
Q
R
L
L
S
D
I
S
H
E
L
R
T
P
L
T
R
L
Q
L
G
T
A
L
-
L
R
R
R
-
S
G
E
--
S
K
E
-----
L
E
R
I
E
T
E
A
Q
R
L
D
S
M
I
N
D
L
L
V
M
S
R
N
Q
-
Q
K
N
-
A
L
V
S
E
T
I
K
A
N
Q
L
W
S
E
----
V
L
D
N
A
A
F
E
A
E
Q
M
-------
G
K
S
L
T
V
N
--
F
--
P
---
P
------------
G
P
W
P
L
Y
G
N
P
N
A
L
E
S
A
L
E
N
I
V
R
N
A
L
R
Y
S
---
H
--
T
---
K
I
E
V
G
F
A
V
D
K
D
G
I
T
I
--
T
V
D
D
D
G
P
G
V
S
P
E
D
R
E
Q
I
F
R
P
F
Y
R
T
D
E
A
R
D
R
E
S
G
G
T
G
L
G
L
A
I
V
E
T
A
I
Q
Q
H
R
G
W
V
K
A
E
D
S
P
L
G
-
G
-
L
R
L
V
I
W
L
P
L
-------------
5
PsiBlast_PDB
63.67
26%
-82
- C2 -
4BIW
5
CPXA_ECOLI
A:
[52-294]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
A
G
P
Q
-
E
F
L
A
A
G
A
S
F
N
Q
V
V
T
A
L
E
R
M
M
T
S
Q
----------------------------------------------------------------------------------------------------------------
Q
-----------
R
L
L
S
D
I
S
H
E
L
R
T
P
L
T
R
L
Q
L
G
T
A
L
-
L
R
R
R
-
S
G
E
--
S
K
E
-----
L
E
R
I
E
T
E
A
Q
R
L
D
S
M
I
N
D
L
L
V
M
S
R
N
Q
-
Q
K
N
-
A
L
V
S
E
T
I
K
A
N
Q
L
W
S
E
----
V
L
D
N
A
A
F
E
A
E
Q
M
-------
G
K
S
L
T
V
N
--
F
--
P
---
P
------------
G
P
W
P
L
Y
G
N
P
N
A
L
E
S
A
L
E
N
I
V
R
N
A
L
R
Y
S
---
H
--
T
---
K
I
E
V
G
F
A
V
D
K
D
G
I
T
I
--
T
V
D
D
D
G
P
G
V
S
P
E
D
R
E
Q
I
F
R
P
F
Y
R
T
D
E
A
R
D
R
E
S
G
G
T
G
L
G
L
A
I
V
E
T
A
I
Q
Q
H
R
G
W
V
K
A
E
D
S
P
L
G
-
G
-
L
R
L
V
I
W
L
P
L
-------------
1
PsiBlast_PDB
62.34
33%
-105
- C2 -
4U7N
-
?
A:
[386-610]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
S
N
V
S
H
E
L
R
T
P
L
T
S
L
R
-
S
Y
I
E
A
L
S
D
G
-
A
W
K
--
D
P
E
V
A
P
G
F
L
K
V
T
Q
E
E
T
D
R
M
I
R
M
I
N
E
L
L
S
L
S
R
M
D
-
S
G
T
-
T
----
R
V
D
M
E
L
V
N
I
N
----
E
M
F
N
Y
V
L
D
R
F
D
M
-------
I
L
K
K
--
D
--
D
--
N
----Y
Y
T
I
K
R
E
F
T
K--
R
D
L
W
V
E
I
D
T
D
K
F
T
Q
V
L
D
N
I
M
N
N
A
I
K
Y
S
---
P
D
G
G
---
V
V
T
C
R
L
L
E
T
H
N
Q
V
I
I
--
S
I
S
D
Q
G
L
G
I
P
R
A
D
L
G
H
V
F
D
R
F
F
R
-----------
T
G
L
G
L
A
I
S
K
E
V
V
Q
M
L
G
G
R
I
W
V
D
S
V
E
-
G
-
K
G
S
T
F
Y
I
S
L
P
-----
Y
E
-------
41
HHSearch
61.11
25%
-89
- C2 -
4BIX
3
CPXA_ECOLI
A:
[61-296]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
G
A
S
F
N
Q
V
V
T
A
L
E
R
M
---------------------------------------------------------------------------------------------------------------------------
M
T
S
Q
Q
R
L
L
S
D
I
S
H
E
L
R
T
P
L
T
R
L
Q
-
L
G
T
A
-
L
L
R
R
-
R
S
------
G
E
S
K
E
L
E
R
I
E
T
E
A
Q
R
L
D
S
M
I
N
D
L
L
V
M
S
R
N
Q
-
Q
K
N
-
A
L
V
S
E
T
I
K
A
N
Q
L
W
S
E
----
V
L
D
N
A
A
F
E
A
E
Q
M
-------
G
K
S
L
T
V
N
--
F
--
P
---
P
------------
G
P
W
P
L
Y
G
N
P
N
A
L
E
S
A
L
E
N
I
V
R
N
A
L
R
Y
S
---
H
T
K
-----
I
E
V
G
F
A
V
D
K
D
G
I
T
I
--
T
V
D
D
D
G
P
G
V
S
P
E
D
R
E
Q
I
F
R
P
F
Y
R
T
D
--------
G
T
G
L
G
L
A
I
V
E
T
A
I
Q
Q
H
R
G
W
V
K
A
E
D
S
P
-
L
G
G
-
L
R
L
V
I
W
L
P
L
--
Y
K
---------
10
PsiBlast_PDB
61.07
26%
-79
- C2 -
4CB0
6
CPXA_ECOLI
A:
[57-294]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
-
E
F
L
A
A
G
A
S
F
N
Q
M
V
-------
T
A
L
----------------------------------------------------------------------------------------------------------------
E
R
M
----
M
T
S
Q
Q
R
L
L
S
D
I
S
H
E
L
R
T
P
L
T
R
L
Q
L
G
T
A
L
-
L
R
R
R
-
S
G
E
--
S
K
E
-----
L
E
R
I
E
T
E
A
Q
R
L
D
S
M
I
N
D
L
L
V
M
S
R
N
Q
-
Q
K
N
-
A
L
V
S
E
T
I
K
A
N
Q
L
W
S
E
----
V
L
D
N
A
A
F
E
A
E
Q
M
-------
G
K
S
L
T
V
N
--
F
--
P
---
P
------------
G
P
W
P
L
Y
G
N
P
N
A
L
E
S
A
L
E
N
I
V
R
N
A
L
R
Y
S
---
H
--
T
---
K
I
E
V
G
F
A
V
D
K
D
G
I
T
I
--
T
V
D
D
D
G
P
G
V
S
P
E
D
R
E
Q
I
F
R
P
F
Y
R
T
D
E
A
R
D
R
E
S
G
G
T
G
L
G
L
A
I
V
E
T
A
I
Q
Q
H
R
G
W
V
K
A
E
D
S
P
L
G
-
G
-
L
R
L
V
I
W
L
P
L
-------------
21
PsiBlast_CBE
54.49
33%
-81
- C2 -
4U7O
1
?
B:
[37-263]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
F
V
S
N
V
S
H
E
L
R
T
P
L
T
S
L
R
-
S
Y
I
E
A
L
S
D
G
-
A
W
K
--
D
P
E
V
A
P
G
F
L
K
V
T
Q
E
E
T
D
R
M
I
R
M
I
N
E
L
L
S
L
S
--------
T
----
R
V
D
M
E
L
V
N
I
N
----
E
M
F
N
Y
V
L
D
R
F
D
M
-------
I
L
K
K
--
D
--
D
--
N
---
P
AKY
Y
T
I
K
R
E
F
T
K
R
D
L
W
V
E
I
D
T
D
K
F
T
Q
V
L
D
N
I
M
N
N
A
I
K
Y
S
---
P
D
G
G
---
V
V
T
C
R
L
L
E
T
H
N
Q
V
I
I
--
S
I
S
D
Q
G
L
G
I
P
R
A
D
L
G
H
V
F
D
R
F
F
R
V
D
K
A
R
---
Q
G
G
T
G
L
G
L
A
I
S
K
E
V
V
Q
M
L
G
G
R
I
W
V
D
S
V
E
-
G
-
K
G
S
T
F
Y
I
S
L
P
-----
Y
E
-------
18
PsiBlast_PDB
41.62
34%
-82
- C2 -
3SL2
2
A:
[29-153]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
--
L
--
P
---
D
------------
R
D
L
Y
V
E
I
D
Q
D
K
I
T
Q
V
L
D
N
I
I
S
N
A
L
K
Y
S
---
P
E
G
G
---
H
V
T
F
S
I
D
V
N
E
E
E
E
L
L
Y
I
S
V
K
D
E
G
I
G
I
P
K
K
D
V
E
K
V
F
D
R
F
Y
R
V
D
------
L
G
G
T
G
L
G
L
A
I
A
K
E
M
V
Q
A
H
G
G
D
I
W
A
D
S
I
E
-
G
-
K
G
T
T
I
T
F
T
L
P
Y
K
E-----------