@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA0217: (2015-12-26 )
MLIDEEITLKKLETFLAFMRTGNLARAAAELGTSNVSVHRAIHSLESALRCPLFKHEGRNLTPLESAYVLEERAQKLVQEVLDTVRLTREAAGFSAERFKLGALYSLTVKTVPQLIMGLKLRRSALNIDLILGSNVDLFYQLKNMELDAILVSLNDSVSDPDCEHLPLFSDDIFLAVPVDSPYARLAEIDLSTLRDTPFVTLTQGFATHQDGTRVFQQAGFEPQIAMQVNDIFTLLSMVSSGVGHALLPKRIEAVYENRVRLIPLQPRYRLQQHIGVVFLKAKERDPNLLALLAECRMYSLRLEQEAAG
Atome Classification :
(20 SA)
.........10........20........30........40........50........--60........70........-80........90..-......-.100.......110.......120.......130.....--..140.......150.......-.160......-.170.......180....--..--.190......-.200--......--.--..210-.........220--........230...-...-.240.......250--....--.--..260-.......--270.......280.......290.......300.......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MLID
E
E
I
T
L
K
K
L
E
T
F
L
A
F
M
RTG
N
L
A
R
A
A
A
E
LGTSN
V
S
V
H
R
A
I
H
S
L
E
S
A
L
RCP
L
F
KHEGR--NLTP
L
E
S
A
Y
V
L
E
E
R
A
Q
K
L
V
Q
-
E
V
L
D
T
V
R
L
T
R
E
-AA-GFS
A
E
R
-
F
KL
G
A
L
Y
S
L
T
V
K
T
V
P
Q
L
I
M
G
L
K
L
R
RSAL
N
I
D
L
I
LGSN
V
D
--
L
F
Y
Q
LKN
M
E
L
D
A
I
L
-
V
SLNDSV-SDPDCEHLPL-FSD
D
I
F
L
A
V
PVD
S
P
Y
A
R
L
--
A
E--I
D
L
S
TLRDT
P
-
F
V
----
T
L
TQGF--A--THQ---
D
G
T
R
V
F
Q
QAG-F--E
P
Q
I
A
M
Q
V
N
D
I
F
T
L
-
L
S
M
-
V
S
SGVGH
A
L
L
P
K
R
I
--
E
A
V
Y
--E--N
R
V
R
L
-
I
PLQ
P
R
Y
--
R
L
Q
QHI
G
V
V
F
L
K
AKERD
P
N
L
L
A
L
L
A
E
C
R
M
Y
S
L
R
L
E
Q
EAAG
3
PsiBlast_PDB
91.86
23%
-131
- C1 -
3K1M
3
BENM_ACIAD
A:
[3-260]
--------
L
R
H
L
R
Y
F
V
A
V
V
E
E
Q
S
F
T
K
A
A
D
K
L
C
I
A
Q
P
P
L
S
R
Q
I
Q
N
L
E
E
E
L
G
I
Q
L
L
E
R
G
S
R
--
P
V
K
T
T
P
E
G
H
F
F
Y
Q
Y
A
I
K
L
L
S
-
N
V
D
Q
M
V
S
M
T
K
R
-
I
A
---
S
V
E
K
T
I
R
I
G
F
V
G
S
L
L
F
G
L
L
P
R
I
I
H
L
Y
R
Q
A
H
P
N
L
R
I
E
L
Y
E
M
G
T
K
A
--
Q
T
E
A
L
K
E
G
R
I
D
A
G
F
-
G
R
L
K
--
I
-
S
D
P
A
I
K
H
T
L
L
-
R
N
E
R
L
M
V
A
V
H
A
S
H
P
L
N
Q
M
--
K
D
K
G
V
H
L
N
D
L
I
D
E
K
-
I
L
L
Y
PS
S
P
K
P
N
F
--
S
--
T
H
V
-----
M
N
I
F
S
D
H
G
-
L
--
E
P
T
K
I
N
E
V
R
E
V
Q
L
A
-
L
G
L
-
V
A
A
G
E
G
I
S
L
V
P
A
S
T
--
Q
S
I
Q
--
L
--
F
N
L
S
Y
-
V
P
L
L
D
P
D
--
A
I
T
P
I
Y
I
A
V
R
N
M
E
E
S
T
Y
I
Y
S
L
Y
E
T
I
R
Q
I
Y
A
Y
E
G
F
T
E
----
7
PsiBlast_PDB
90.57
23%
-130
- C1 -
3K1N
2
BENM_ACIAD
A:
[3-260]
--------
L
R
H
L
R
Y
F
V
A
V
V
E
E
Q
S
F
T
K
A
A
D
K
L
C
I
A
Q
P
P
L
S
R
Q
I
Q
N
L
E
E
E
L
G
I
Q
L
L
E
R
G
S
R
--
P
V
K
T
T
P
E
G
H
F
F
Y
Q
Y
A
I
K
L
L
S
-
N
V
D
Q
M
V
S
M
T
K
R
-
I
A
---
S
V
E
K
T
I
R
I
G
F
V
G
S
L
L
F
G
L
L
P
R
I
I
H
L
Y
R
Q
A
H
P
N
L
R
I
E
L
Y
E
M
G
T
K
A
--
Q
T
E
A
L
K
E
G
R
I
D
A
G
F
-
G
R
L
K
--
I
-
S
D
P
A
I
K
R
T
L
L
-
R
N
E
R
L
M
V
A
V
H
A
S
H
P
L
N
Q
M
--
K
D
K
G
V
H
L
N
D
L
I
D
E
K
-
I
L
L
Y
P
S
S
P
K
P
N
F
--
S
--
T
H
V
-----
M
N
I
F
S
D
H
G
-
L
--
E
P
T
K
I
N
E
V
R
E
V
Q
L
A
-
L
G
L
-
V
A
A
G
E
G
I
S
L
V
P
A
S
T
--
Q
S
I
Q
--
L
--
F
N
L
S
Y
-
V
P
L
L
D
P
D
--
A
I
T
P
I
Y
I
A
V
R
N
M
E
E
S
T
Y
I
Y
S
L
Y
E
T
I
R
Q
I
Y
A
Y
E
G
F
T
E
P
P
N
-
43
Fugue
90.56
18%
-106
- C1 -
1IZ1
-
?
A:
[1-292]
------
M
E
F
R
Q
L
K
Y
F
I
A
V
A
E
A
G
N
M
A
A
A
A
K
R
L
H
V
S
Q
P
P
I
T
R
Q
M
Q
A
L
E
A
D
L
G
V
V
L
L
E
R
S
H
R
--
G
I
E
L
T
A
A
G
H
A
F
L
E
D
A
R
R
I
L
E
-
L
A
G
R
S
G
D
R
S
R
A
-
A
A
-
R
G
D
V
G
E
-
L
S
V
A
Y
F
G
T
P
I
Y
R
S
L
P
L
L
L
R
A
F
L
T
S
T
P
T
A
T
V
S
L
T
H
M
T
K
D
E
--
Q
V
E
G
L
L
A
G
T
I
H
V
G
F
-
S
R
F
--
F
P
-
R
H
P
G
I
E
I
V
N
I
-
A
Q
E
D
L
Y
L
A
V
H
R
S
Q
S
G
K
F
G
--
K
T
--
C
K
L
A
D
L
R
A
V
E
-
L
T
----
L
F
P
R
G
G
--
R
PS
F
A
D
---
E
V
I
G
L
F
K
H
A
G
-
I
--
E
P
R
I
A
R
V
V
E
D
A
T
A
A
-
L
A
L
-
T
M
A
G
A
A
S
S
I
V
P
A
S
V
--
A
A
I
R
--
W
--
P
D
I
A
F
-
A
R
I
V
G
T
---
R
V
K
V
P
I
S
C
I
F
R
K
-
E
K
Q
P
P
I
L
A
R
F
V
E
H
V
R
R
S
A
---------
22
HHSearch
90.23
18%
-106
- C1 -
3FXQ
7
TSAR_COMTE
A:
[1-296]
-----
M
L
K
L
Q
T
L
Q
A
L
I
C
I
E
E
V
G
S
L
R
A
A
A
Q
L
L
H
L
S
Q
P
A
L
S
A
A
I
Q
Q
L
E
D
E
L
K
A
P
L
L
V
R
T
K
R
--
G
V
S
L
T
S
F
G
Q
A
F
M
K
H
A
R
L
I
V
T
-
E
S
R
R
A
Q
E
E
I
G
Q
-
L
R
-
G
R
W
E
G
H
-
I
T
F
A
A
S
P
A
I
A
L
A
A
L
P
L
A
L
A
S
F
A
R
E
F
P
D
V
T
V
N
V
R
D
G
M
Y
P
A
--
V
S
P
Q
L
R
D
G
T
L
D
F
A
L
-
T
A
A
H
K
H
D
-
I
D
T
D
L
E
A
Q
P
L
-
Y
V
S
D
V
V
I
V
G
Q
R
Q
H
P
M
A
N
----
A
--
T
R
L
A
E
L
Q
E
C
R
-
W
A
----
F
S
S
A
P
R
--
G
--
P
G
A
---
I
I
R
N
A
F
A
R
Y
G
-
L
P-
E
P
K
L
G
L
V
C
E
S
F
L
A
L
-
P
G
V
-
V
A
H
S
D
L
L
T
T
M
P
R
T
L
--
Y
E
R
N
AF
K
--
D
Q
L
C
S
-
I
P
L
Q
D
A
L
---
P
N
P
T
I
Y
V
L
R
R
H
D
L
P
V
T
P
A
A
A
G
L
I
R
W
I
Q
H
H
A
L
--------
8
PsiBlast_PDB
87.12
23%
-124
- C1 -
3K1P
-
BENM_ACIAD
A:
[3-260]
--------
L
R
H
L
R
Y
F
V
A
V
V
E
E
Q
S
F
T
K
A
A
D
K
L
C
I
A
Q
P
P
L
S
R
Q
I
Q
N
L
E
E
E
L
G
I
Q
L
L
E
R
G
S
R
--
P
V
K
T
T
P
E
G
H
F
F
Y
Q
Y
A
I
K
L
L
S
-
N
V
D
Q
M
V
S
M
T
K
R
-
I
A
---
S
V
E
K
T
I
R
I
G
F
V
G
S
L
L
F
G
L
L
P
R
I
I
H
L
Y
R
Q
A
H
P
N
L
R
I
E
L
Y
E
M
G
T
K
A
--
Q
T
E
A
L
K
E
G
R
I
D
A
G
F
-
G
R
L
K
--
I
-
S
D
P
A
I
K
R
T
L
L
-
R
N
E
R
L
M
V
A
V
H
A
S
H
P
L
N
Q
M
--
K
D
K
G
V
H
L
N
D
L
I
D
E
K
-
I
L
L
Y
PS
S
P
K
P
N
F
--
S
--
T
H
V
-----
M
N
I
F
S
D
H
G
-
L
--
E
P
T
K
I
N
E
V
R
K
V
Q
L
A
-
L
G
L
-
V
A
A
G
E
G
I
S
L
V
P
A
S
T
--
Q
S
I
Q
--
L
--
F
N
L
S
Y
-
V
P
L
L
D
P
D
--
A
I
T
P
I
Y
I
A
V
R
N
M
E
E
S
T
Y
I
Y
S
L
Y
E
T
I
R
Q
I
Y
A
Y
E
G
F
T
E
P
P
N
-
44
Fugue
84.08
20%
-100
- C1 -
3FZV
1
?
A:
[4-300]
------
Y
T
L
R
Q
L
K
Y
F
V
T
T
V
E
C
G
S
V
A
E
A
S
R
K
L
Y
I
A
Q
-
S
I
S
T
A
V
K
G
L
E
E
S
F
V
-----------
Q
L
F
L
T
P
A
G
A
R
F
Y
R
K
A
Q
E
L
L
R
M
A
H
E
F
E
Q
N
L
A
D
N
----
D
V
I
A
G
Q
-
I
D
I
G
C
F
E
T
V
A
P
L
Y
L
P
G
L
I
A
G
F
R
Q
A
Y
P
G
V
E
I
R
I
R
D
G
E
Q
Q
E
--
L
V
Q
G
L
T
S
G
R
F
D
L
A
F
-
L
Y
E
H
D
L
---
D
S
T
I
E
T
E
P
L
M
P
P
Q
R
P
H
A
L
L
P
E
G
H
R
F
A
G
Q
--
A
Q
--
V
S
L
R
D
L
C
L
E
P
M
I
L
----
L
D
V
Q
P
------
S
R
T
---
Y
F
V
S
L
F
E
E
L
G
-
L
--
T
P
N
I
A
F
S
S
P
S
I
--
E
M
V
R
G
M
V
G
Q
G
F
G
F
S
L
L
V
T
R
P
--
H
S
E
C
TY
D
--
G
K
K
V
V
M
V
D
L
A
E
P
V
--
S
-
T
S
G
L
A
A
A
W
L
K
R
A
Q
L
T
K
P
A
R
L
F
V
D
Y
C
R
E
Q
L
G
K
-------
2
PsiBlast_PDB
82.60
24%
-125
- C1 -
4X6G
4
?
A:
[7-250]
------
M
T
L
T
E
L
R
Y
I
V
T
L
A
Q
E
Q
H
F
G
R
A
A
E
R
C
H
V
S
Q
P
T
L
S
V
G
V
K
K
L
E
D
E
L
G
V
L
I
F
E
R
S
K
S
AV
R
L
T
P
V
G
E
G
I
V
A
Q
--
A
Q
K
V
L
E
-
Q
A
Q
G
I
R
E
L
A
Q
A
-
G
K
-
N
Q
L
A
A
P
-
L
K
V
G
A
I
Y
T
I
G
P
Y
L
F
P
H
L
I
P
--
Q
L
H
R
V
A
P
Q
M
P
L
Y
I
E
E
N
F
T
H
I
L
R
D
K
L
R
T
G
E
L
D
A
I
I
-
I
A
L
--
P
F
-
Q
E
A
D
V
L
T
K
P
L
-
F
D
E
P
F
Y
V
L
M
P
A
D
H
P
W
T
A
K
--
A
S
--
I
D
S
E
L
L
N
D
K
S
-
L
L
----
L
L
G
E
G
H
--
D
--
F
R
D
Q
V
L
E
A
C
P
T
V
R
K
G
D
-
E
--
N
K
H
T
T
V
E
S
S
S
L
E
T
I
-
R
H
M
-
V
A
S
G
L
G
V
S
V
L
P
F
S
A
--
V
D
S
H
--
H
--
Y
A
P
G
V
-
I
E
V
R
P
F
S
--
A
P
V
P
F
R
T
V
A
I
A
W
R
A
S
F
P
R
P
R
A
I
E
V
L
A
D
S
I
R
L
C
S
-------
46
Fugue
80.96
15%
-103
- C1 -
2ESN
-
?
A:
[3-303]
-
P
L
L
R
R
L
D
L
N
L
L
L
V
F
D
A
L
Y
R
H
R
N
V
G
T
A
A
S
E
L
A
I
S
A
S
A
F
S
H
A
L
G
R
L
R
Q
G
L
D
D
E
L
F
L
R
Q
G
N
--
R
M
Q
P
T
Q
R
A
E
H
L
A
A
A
V
A
A
A
L
R
-
A
L
G
E
G
L
E
E
W
R
P
F
V
P
-
G
Q
S
Q
R
T
-
F
V
F
A
A
T
D
Y
T
A
F
A
L
L
P
P
L
M
N
R
L
Q
H
S
A
P
G
V
R
L
R
L
V
N
A
E
R
K
L
--
S
V
E
A
L
A
S
G
R
I
D
F
A
L
G
Y
D
E
E
H
E
R
-
L
P
E
G
I
Q
A
H
D
W
-
F
A
D
R
Y
V
V
V
A
R
R
D
H
P
R
L
A
---
G
A
--
P
T
L
E
G
Y
L
A
E
R
-
H
A
----
V
V
T
P
W
N
--
E
--
D
S
G
---
V
I
D
R
L
L
A
R
S
G
-
L
--
R
R
E
V
A
V
Q
L
P
T
V
L
A
A
-
L
F
L
-
A
G
S
T
D
F
L
L
T
A
P
R
H
A
--
A
R
A
L
--
A
--
E
A
A
G
L
-
A
L
Y
P
A
P
F
--
D
I
P
P
-
Y
V
L
R
L
Y
S
H
V
Q
G
R
D
A
H
A
W
M
I
G
Q
L
K
G
L
D
---------
23
HHSearch
80.96
16%
-101
- C1 -
2ESN
-
?
A:
[3-303]
-
P
L
L
R
R
L
D
L
N
L
L
L
V
F
D
A
L
Y
R
H
R
N
V
G
T
A
A
S
E
L
A
I
S
A
S
A
F
S
H
A
L
G
R
L
R
Q
G
L
D
D
E
L
F
L
R
Q
G
N
--
R
M
Q
P
T
Q
R
A
E
H
L
A
A
A
V
A
A
A
L
R
-
A
L
G
E
G
L
E
E
W
R
P
-
F
V
P
G
Q
S
Q
R
T
-
F
V
F
A
A
T
D
Y
T
A
F
A
L
L
P
P
L
M
N
R
L
Q
H
S
A
P
G
V
R
L
R
L
V
N
A
E
R
K
L
--
S
V
E
A
L
A
S
G
R
I
D
F
A
L
-
G
Y
D
E
E
H
E
R
L
P
E
G
I
Q
A
H
D
W
-
F
A
D
R
Y
V
V
V
A
R
R
D
H
P
R
L
A
G
---
A
--
P
T
L
E
G
Y
L
A
E
R
-
H
A
----
V
V
T
P
W
N
--
E
--
D
S
G
---
V
I
D
R
L
L
A
R
S
G
-
L
--
R
R
E
V
A
V
Q
L
P
T
V
L
A
A
-
L
F
L
-
A
G
S
T
D
F
L
L
T
A
P
R
H
A
--
A
R
A
L
A
E
A
--
A
G
L
A
L
-
Y
P
A
P
F
D
---
I
P
P
Y
V
L
R
L
Y
S
H
V
Q
--
G
R
D
A
H
A
W
M
I
G
Q
L
K
G
L
D
---------
27
HHSearch
76.95
21%
-118
- C1 -
2H9B
5
BENM_ACIAD
A:
[89-296]
----------------------------------------------------------------------------------------------------
E
K
T
-
I
R
I
G
F
V
G
S
L
L
F
G
L
L
P
R
I
I
H
L
Y
R
Q
A
H
P
N
L
R
I
E
L
Y
E
M
G
T
K
A
--
Q
T
E
A
L
K
E
G
R
I
D
A
G
F
-
G
R
L
K
I
S
---
D
P
A
I
K
H
S
L
L
-
R
N
E
R
L
M
V
A
V
H
A
S
H
P
L
N
Q
M
KD
K
G
--
V
H
L
N
D
L
I
D
E
K
-
I
L
----
L
Y
P
S
S
P
KP
N
--
F
S
T
---
H
V
M
N
I
F
S
D
H
G
-
L
--
E
P
T
K
I
N
E
V
R
E
V
Q
L
A
-
L
G
L
-
V
A
A
G
E
G
I
S
L
V
P
A
S
T
--
Q
S
I
Q
--
L
--
F
N
L
S
Y
-
V
P
L
L
D
P
D
---
A
I
T
P
I
Y
I
A
V
R
N
M
E
-
E
S
T
Y
I
Y
S
L
Y
E
T
I
R
Q
I
Y
A
Y
E
G
F
T
E
P
P
29
HHSearch
74.85
17%
-102
- C1 -
3HHG
-
?
A:
[2-294]
-----
K
T
N
S
E
E
L
T
V
F
V
Q
V
V
E
S
G
S
F
S
R
A
A
E
Q
L
A
M
A
N
S
A
V
S
R
I
V
K
R
L
E
E
K
L
G
V
N
L
L
N
R
T
T
R
--
Q
L
S
L
T
E
E
G
A
Q
Y
F
R
R
A
Q
R
I
L
Q
-
E
M
A
A
A
E
T
E
M
L
A
-
V
H
-
E
I
P
Q
G
V
-
L
S
V
D
S
A
M
P
M
V
L
H
L
L
A
P
L
A
A
K
F
N
E
R
Y
P
H
I
R
L
S
L
V
S
S
E
-----
G
Y
I
N
L
I
E
R
K
V
D
I
A
L
-
R
A
G
E
L
D
---
D
S
G
L
R
A
R
H
L
-
F
D
S
R
F
R
V
I
A
S
P
E
Y
L
A
K
H
G
--
T
P
--
Q
S
T
E
E
L
A
G
H
Q
-
C
L
----
G
F
T
E
P
G
--
S
--
L
N
T
---
W
--
A
V
L
D
A
Q
G
-
N
PY
K
I
S
P
H
F
T
A
S
S
G
E
I
L
-
R
S
L
-
C
L
S
G
C
G
I
V
C
L
S
D
F
L
--
V
D
N
D
--
I
--
A
E
G
K
L
-
I
P
L
L
A
E
Q
TS
D
K
T
H
P
F
N
A
V
Y
Y
S
D
K
A
V
N
L
R
L
R
V
F
L
D
F
L
V
E
E
L
G
--------
39
HHSearch
72.98
20%
-105
- C1 -
2QL3
-
?
A:
[3-207]
---------------------------------------------------------------------------------------------------
V
A
G
P
-
I
A
V
G
C
Y
P
A
L
G
P
T
I
L
P
S
M
L
Y
A
F
T
A
E
Y
P
R
A
S
V
E
F
R
E
D
T
Q
N
R
--
L
R
T
Q
L
E
G
G
E
L
D
V
A
I
-
V
Y
D
L
D
L
---
S
P
E
W
Q
T
V
P
L
-
M
T
R
E
P
M
V
V
L
G
A
E
H
P
L
A
G
V
D-
G
P
--
V
R
L
A
D
L
A
E
H
P
-
M
V
----
L
L
D
A
P
P
--
S
--
T
-
N
---
H
A
M
D
V
C
R
E
A
G
-
F
--
A
P
R
V
A
Y
R
T
A
N
F
E
T
A
-
R
A
F
-
V
G
R
G
L
G
W
T
L
L
L
Q
R
P
--
R
V
D
V
TY
E
G-
L
P
V
V
V
-
K
P
I
A
E
P
K
--
P
A
S
V
A
V
V
V
A
W
H
Q
E
A
T
L
S
R
V
A
R
A
F
I
R
F
V
T
A
-----------
25
HHSearch
71.60
18%
-110
- C1 -
2H98
2
CATM_ACIAD
A:
[89-300]
----------------------------------------------------------------------------------------------------
S
Q
T
-
L
R
I
G
Y
V
S
S
L
L
Y
G
L
L
P
E
I
I
Y
L
F
R
Q
Q
N
P
E
I
H
I
E
L
I
E
C
G
T
K
D
--
Q
I
N
A
L
K
Q
G
K
I
D
L
G
F
-
G
R
L
K
I
T
---
D
P
A
I
R
R
I
M
L
-
H
K
E
Q
L
K
L
A
I
H
K
H
H
H
L
N
Q
F
AA
T
G
--
V
H
L
S
Q
I
I
D
E
P
-
M
L
----
L
Y
P
V
S
Q
KP
N
--
F
A
T
---
F
I
Q
S
L
F
T
E
L
G
-
L
--
V
P
S
K
L
T
E
I
R
E
I
Q
L
A
-
L
G
L
-
V
A
A
G
E
G
V
C
I
V
P
A
S
A
--
M
D
I
G
--
V
--
K
N
L
L
Y
-
I
P
I
L
D
D
D
---
A
Y
S
P
I
S
L
A
V
R
N
M
D
-
H
S
N
Y
I
P
K
I
L
A
C
V
Q
E
V
F
A
T
H
H
I
R
P
L
I
5
PsiBlast_PDB
70.72
23%
-135
- C1 -
2H9B
5
BENM_ACIAD
A:
[89-260]
-----------------------------------------------------------------------------------------------------
E
K
T
I
R
I
G
F
V
G
S
L
L
F
G
L
L
P
R
I
I
H
L
Y
R
Q
A
H
P
N
L
R
I
E
L
Y
E
M
G
T
K
A
--
Q
T
E
A
L
K
E
G
R
I
D
A
G
F
-
G
R
L
K
--
I
-
S
D
P
A
I
K
H
S
L
L
-
R
N
E
R
L
M
V
A
V
H
A
S
H
P
L
N
Q
M
--
K
D
KG
V
H
L
N
D
L
I
D
E
K
-
I
L
L
Y
PS
S
P
K
P
N
F
--
S
--
T
H
V
-----
M
N
I
F
S
D
H
G
-
L
--
E
P
T
K
I
N
E
V
R
E
V
Q
L
A
-
L
G
L
-
V
A
A
G
E
G
I
S
L
V
P
A
S
T
--
Q
S
I
Q
--
L
--
F
N
L
S
Y
-
V
P
L
L
D
P
D
--
A
I
T
P
I
Y
I
A
V
R
N
M
E
E
S
T
Y
I
Y
S
L
Y
E
T
I
R
Q
I
Y
A
Y
E
G
F
T
E
P
P
N
W
4
PsiBlast_PDB
70.63
23%
-136
- C1 -
2H99
5
BENM_ACIAD
A:
[90-260]
------------------------------------------------------------------------------------------------------
K
T
I
R
I
G
F
V
G
S
L
L
F
G
L
L
P
R
I
I
H
L
Y
R
Q
A
H
P
N
L
R
I
E
L
Y
E
M
G
T
K
A
--
Q
T
E
A
L
K
E
G
R
I
D
A
G
F
-
G
R
L
K
--
I
-
S
D
P
A
I
K
H
S
L
L
-
R
N
E
R
L
M
V
A
V
H
A
S
H
P
L
N
Q
M
--
K
D
KG
V
H
L
N
D
L
I
D
E
K
-
I
L
L
Y
PS
S
P
K
P
N
F
--
S
--
T
H
V
-----
M
N
I
F
S
D
H
G
-
L
--
E
P
T
K
I
N
E
V
R
E
V
Q
L
A
-
L
G
L
-
V
A
A
G
E
G
I
S
L
V
P
A
S
T
--
Q
S
I
Q
--
L
--
F
N
L
S
Y
-
V
P
L
L
D
P
D
--
A
I
T
P
I
Y
I
A
V
R
N
M
E
E
S
T
Y
I
Y
S
L
Y
E
T
I
R
Q
I
Y
A
Y
E
G
F
T
E
P
P
N
W
34
HHSearch
69.10
20%
-111
- C1 -
1I6A
-
OXYR_ECOLI
A:
[89-298]
---------------------------------------------------------------------------------------------------
M
S
G
P
-
L
H
I
G
L
I
P
T
V
G
P
Y
L
L
P
H
I
I
P
M
L
H
Q
T
F
P
K
L
E
M
Y
L
H
E
A
Q
T
H
Q
--
L
L
A
Q
L
D
S
G
K
L
D
A
V
I
-
L
A
L
V
K
E
---
S
E
A
F
I
E
V
P
L
-
F
D
E
P
M
L
L
A
I
Y
E
D
H
P
W
A
N
R
--
E
A
--
V
P
M
A
D
L
A
G
E
K
-
L
L
----
M
L
E
D
G
H
--
C
--
L
R
D
---
Q
A
M
G
F
C
F
E
A
G
-
A
--
D
E
D
T
H
F
R
A
T
S
L
E
T
L
-
R
N
M
-
V
A
A
G
S
G
I
T
L
L
P
A
L
A
--
V
P
P
E
RK
R
--
D
G
V
V
Y
-
L
P
A
I
K
P
---
E
P
R
R
T
I
G
L
V
Y
R
P
G
S
P
L
R
S
R
Y
E
Q
L
A
E
A
I
R
A
R
M
D
G
H
F
D
----
30
HHSearch
68.75
14%
-94
- C1 -
3SZP
-
?
A:
[1-289]
------
M
K
L
D
D
L
N
L
F
R
L
V
V
E
N
G
S
Y
T
S
T
S
K
K
T
M
I
P
V
A
T
I
T
R
R
I
Q
A
L
E
D
S
L
N
L
R
L
L
N
R
H
A
R
--
K
L
T
L
T
E
A
G
E
R
F
Y
K
D
C
S
P
L
L
E
-
R
L
A
S
M
T
E
E
I
T
D
-
E
C
-
R
G
A
S
G
R
-
I
R
I
S
A
P
S
N
L
T
K
R
M
M
M
P
M
F
N
A
F
M
E
K
Y
P
D
I
H
I
E
L
M
M
S
N
Q
-----
A
D
D
L
D
P
T
E
W
D
V
I
F
-
R
V
G
P
Q
R
---
D
S
S
L
I
A
R
K
I
-
G
E
V
K
D
I
L
V
A
S
P
Q
Y
L
S
S
H
P
--
Q
P
--
T
H
A
E
E
L
H
Q
H
Q
-
L
L
----
K
G
Y
P
L
L
-----
K
W
Q
----
L
T
N
S
Q
G
E
T
V
V
N
--
S
D
R
G
R
F
Q
A
S
A
L
N
V
V
-
R
S
A
-
C
S
E
G
L
G
I
T
L
M
P
D
V
M
--
L
R
E
F
--
L
E
D
G
S
L
V
Q
-
V
L
S
D
W
S
---
S
N
P
R
D
I
Y
M
L
Y
N
H
K
D
H
Q
P
E
K
V
R
L
F
I
D
F
V
I
G
Y
H
L
--------
45
Fugue
68.58
20%
-112
- C1 -
1I6A
-
OXYR_ECOLI
A:
[87-298]
---------------------------------------------------------------
E
T
M
S
G
----------------------------------
P
-
L
H
I
G
L
I
P
T
V
G
P
Y
L
L
P
H
I
I
P
M
L
H
Q
T
F
P
K
L
E
M
Y
L
H
E
A
Q
T
H
Q
--
L
L
A
Q
L
D
S
G
K
L
D
A
V
I
-
L
A
L
V
K
E
S
-
E
A
F
--
I
E
V
P
L
-
F
D
E
P
M
L
L
A
I
Y
E
D
H
P
W
A
N
R
--
E
A
--
V
P
M
A
D
L
A
G
E
K
-
L
L
----
M
L
E
D
G
H
--
C
--
L
R
D
---
Q
A
M
G
F
C
F
E
A
G
-
A
--
D
E
D
T
H
F
R
A
T
S
L
E
T
L
-
R
N
M
-
V
A
A
G
S
G
I
T
L
L
P
A
L
A
VP
P
E
R
K
--
R
--
D
G
V
V
Y
-
L
P
A
I
K
P
---
E
P
R
R
T
I
G
L
V
Y
R
P
G
S
P
L
R
S
R
Y
E
Q
L
A
E
A
I
R
A
R
M
D
G
H
F
D
----
47
Fugue
67.14
19%
-109
- C1 -
1I6A
-
OXYR_ECOLI
A:
[87-298]
-----------------------------------------------------------------------------------------------
E
--
T
M
S
G
P
-
L
H
I
G
L
I
P
T
V
G
P
Y
L
L
P
H
I
I
P
M
L
H
Q
T
F
P
K
L
E
M
Y
L
H
E
A
Q
T
H
Q
--
L
L
A
Q
L
D
S
G
K
L
D
A
V
I
-
L
A
-
L
V
-
K
-
E
S
E
A
F
I
E
V
P
L
-
F
D
E
P
M
L
L
A
I
Y
E
D
H
P
W
A
N
R
--
E
A
--
V
P
M
A
D
L
A
G
E
K
-
L
L
----
M
L
E
D
G
H
--
C
--
L
R
D
---
Q
A
M
G
F
C
F
E
A
G
-
A
--
D
E
D
T
H
F
R
A
T
S
L
E
T
L
-
R
N
M
-
V
A
A
G
S
G
I
T
L
L
P
A
L
A
VP
P
E
R
K
--
R
--
D
G
V
V
Y
-
L
P
A
I
K
P
---
E
P
R
R
T
I
G
L
V
Y
R
P
G
S
P
L
R
S
R
Y
E
Q
L
A
E
A
I
R
A
R
M
D
-
G
H
F
D
---
36
HHSearch
66.98
17%
-102
* C1 *
2FYI
-
CBL_ECOLI
A:
[89-296]
-------------------------------------------------------------------------------------------------
N
D
T
S
G
V
-
L
T
I
A
T
T
H
T
Q
A
R
Y
S
L
P
E
V
I
K
A
F
R
E
L
F
P
E
V
R
L
E
L
I
Q
G
T
P
Q
E
--
I
A
T
L
L
Q
N
G
E
A
D
I
G
I
-
A
S
E
R
L
S
--
N
D
P
Q
L
V
A
F
P
W
-
F
R
W
H
H
S
L
L
V
P
H
D
H
P
L
T
Q
I
--
S
P
--
L
T
L
E
S
I
A
K
W
P
-
L
I
----
T
Y
R
Q
G
I
--
T
--
G
R
S
---
R
I
D
D
A
F
A
R
K
G
-
L
--
L
A
D
I
V
L
S
A
Q
D
S
D
V
I
-
K
T
Y
-
V
A
L
G
L
G
I
G
L
V
A
E
Q
S
--
S
G
E
Q
--
E
E-
E
N
L
I
R
-
L
D
T
R
H
L
---
F
D
A
N
T
V
W
L
G
L
K
R
G
Q
L
Q
R
N
Y
V
W
R
F
L
E
L
C
N
A
G
L
S
V
E
D
I
K
R
Q
V