@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA1789: (2016-02-01 )
MQAIRSILVVIEPDQLEGLALKRAQLIAGVTQSHLHLLVCEKRRDHSAALNDLAQELREEGYSVSTNQAWKDSLHQTIIAEQQAEGCGLIIKQHFPDNPLKKAILTPDDWKLLRFAPCPVLMTKTARPWTGGKILAAVDVGNNDGEHRSLHAGIISHAYDIAGLAKATLHVISAHPSPMLSSADPTFQLSETIEARYREACRTFQAEYGFSDEQLHIEEGPADVLIPRTAQKLDAVVTVIGTVARTGLSGALIGNTAEVVLDTLESDVLVLKPDDIIAHLEELASKE
Atome Classification :
(20 SA)
----------.........10..-......20...----...---------.-.30....----------....40-----...--------.--------.-------------------.----------------.-----------------..----50---.----........----60.-..---...--.-.70........80-........90.........100........110.......120......----.130........140.......150.......160......--.170...-.-.-..-----180..-------.....190--.----.-.......200....---.-..210-..--......220.......230.......240.......250.......260.......270.......280.....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------MQ
A
I
R
S
I
L
V
V
IEP-DQLE
G
L
A
L
K
R
A
----
Q
L
I
---------
A
-
G
V
T
Q
S
H
L
----------
H
L
L
V
C------EKR--------R--------D-------------------
H
----------------
S
-----------------
A
A
----
L
----
N
----
D
L
A
Q
E
L
R
E----EGY-SV---ST
N
--
Q
-
A
W
K
D
S
L
H
Q
T
I
I
A
E
-QQAEG
C
G
L
I
-
I
KQHFPDN
P
L
-
K
KAILTPDD
W
K
L
L
R
FAPCP
V
L
M
TKTARP----WT-G
G
K
I
L
A
A
V
D
VGNNDGE
H
R
S
L
H
A
G
I
I
S
H
A
Y
D
I
A
G
L
A
K
A
T
--
L
H
V
ISAH-P-S-PM-----LSSAD-------P
T
F
Q
L
S
----
E
----
T
-
I
E
A
R
Y
R
E
A
C
R
T
F
Q
A
---E-YGFS--D
E
--
Q
L
H
IEEGPA
D
V
LIPR
T
A
Q
K
L
D
A
V
V
T
V
I
G
T
V
A
R
TGLS
G
A
LIG
N
T
A
E
V
V
L
D
T
LES
D
V
L
V
LK
P
D
D
I
I
A
H
L
E
E
L
ASKE
14
HHSearch
96.83
100%
-133
- C2 -
3MT0
3
?
A:
[4-290]
----------
M
Q
A
I
R
S
I
L
V
V
I
E
P
-
D
Q
L
E
G
L
A
L
K
R
A
----
Q
L
I
---------
A
-
G
V
T
Q
S
H
L
----------
H
L
L
V
C
------
E
K
R
--------
R
--------
D
-------------------
H
----------------
S
-----------------
A
A
----
L
----
N
----
D
L
A
Q
E
L
R
E
----
E
G
Y
-
S
V
---
S
T
N
--
Q
-
A
W
K
D
S
L
H
Q
T
I
I
A
E
-
Q
Q
A
E
G
C
G
L
I
-
I
K
Q
H
F
P
D
N
P
L
-
K
K
A
I
L
T
P
D
D
W
K
L
L
R
F
A
P
C
P
V
L
M
T
K
T
A
R
P
----
W
T
-
G
G
K
I
L
A
A
V
D
V
G
N
N
D
G
E
H
R
S
L
H
A
G
I
I
S
H
A
Y
D
I
A
G
L
A
K
A
T
--
L
H
V
I
S
A
H
-
P
-----------------------
T
F
Q
L
S
----
E
----
T
-
I
E
A
R
Y
R
E
A
C
R
T
F
Q
A
---
E
-
Y
G
F
S
--
D
E
--
Q
L
H
I
E
E
G
P
A
D
V
L
I
P
R
T
A
Q
K
L
D
A
V
V
T
V
I
G
T
V
A
R
T
G
L
S
G
A
L
I
G
N
T
A
E
V
V
L
D
T
L
E
S
D
V
L
V
L
K
P
D
D
I
I
A
H
L
E
E
L
A
S
K
E
1
PsiBlast_PDB
96.30
99%
-130
- C2 -
3MT0
3
?
A:
[5-290]
-----------
Q
A
I
R
S
I
L
V
V
I
E
P
-
D
Q
L
E
G
L
A
L
K
R
A
----
Q
L
I
---------
A
-
G
V
T
Q
S
H
L
----------
H
L
L
V
C
------
E
K
R
--------
R
--------
D
-------------------
H
----------------
S
-----------------
A
A
----
L
----
N
----
D
L
A
Q
E
L
R
E
----
E
G
Y
-
S
V
---
S
T
N
--
Q
-
A
W
K
D
S
L
H
Q
T
I
I
A
E
-
Q
Q
A
E
G
C
G
L
I
-
I
K
Q
H
F
P
D
N
P
L
-
K
K
A
I
L
T
P
D
D
W
K
L
L
R
F
A
P
C
P
V
L
M
T
K
T
A
R
P
----
W
T
-
G
G
K
I
L
A
A
V
D
V
G
N
N
D
G
E
H
R
S
L
H
A
G
I
I
S
H
A
Y
D
I
A
G
L
A
K
A
T
--
L
H
V
I
S
A
H
-
P
-----------------------
T
F
Q
L
S
----
E
----
T
-
I
E
A
R
Y
R
E
A
C
R
T
F
Q
A
---
E
-
Y
G
F
S
--
D
E
--
Q
L
H
I
E
E
G
P
A
D
V
L
I
P
R
T
A
Q
K
L
D
A
V
V
T
V
I
G
T
V
A
R
T
G
L
S
G
A
L
I
G
N
T
A
E
V
V
L
D
T
L
E
S
D
V
L
V
L
K
P
D
D
I
I
A
H
L
E
E
L
A
S
K
E
2
PsiBlast_PDB
71.41
31%
-113
- C2 -
4R2J
5
USPE_SALTY
A:
[17-317]
------------
M
Y
Q
N
M
L
V
V
I
D
P
-
N
Q
D
D
Q
P
A
L
R
R
A
V
Y
L
H
Q
R
I
---------
G
-
G
K
I
K
A
F
L
P
I
Y
D
FSYEMT-
L
L
S
P
------
D
E
R
T
A
M
R
Q
G
V
I
S
--------
Q
-------------------
R
----------------
T
-----------------
A
W
----
I
----
R
----
E
Q
A
K
Y
Y
L
E
----
A
G
V
-
P
I
---
E
I
K
--
V
-
V
W
H
N
R
P
F
E
A
I
I
Q
E
-
V
I
A
G
S
H
D
L
V
-
L
K
M
A
H
Q
H
D
R
L
-
E
A
V
I
F
T
P
T
D
W
H
L
L
R
K
C
P
S
P
V
W
M
V
K
D
-
Q
P
----
W
P
E
G
G
K
A
L
V
A
V
N
L
A
---
P
Y
H
N
A
L
N
E
K
L
V
K
E
T
L
Q
L
A
E
Q
V
N
H
T
E
-
V
H
L
V
G
A
Y
-
P
V
T
-
P
I
NIAIE------------
P
S
V
-
Y
N
----
D
----
A
-
I
R
G
Q
H
L
L
A
M
K
A
L
R
Q
---
K
-
F
S
I
D
--
E
K
--
V
T
H
V
E
K
G
L
P
E
E
V
I
P
D
L
A
E
H
L
Q
A
G
I
V
V
L
G
T
V
-------
A
F
L
G
N
T
A
E
Q
V
I
D
H
L
R
C
D
L
L
V
I
K
P
D
E
------------
3
PsiBlast_PDB
70.09
31%
-102
- C2 -
4R2K
24
USPE_SALTY
A:
[15-317]
----------
M
A
M
Y
Q
N
M
L
V
V
I
D
P
-
N
Q
D
D
Q
P
A
L
R
R
A
V
Y
L
H
Q
R
I
---------
G
-
G
K
I
K
A
F
L
P
I
YDF
S
Y
E
M
T
T
L
L
S
P
------
D
E
R
T
A
M
R
Q
G
V
I
S
--------
Q
-------------------
R
----------------
T
-----------------
A
W
----
I
----
R
----
E
Q
A
K
Y
Y
L
E
----
A
G
V
-
P
I
---
E
I
K
--
V
-
V
W
H
N
R
P
F
E
A
I
I
Q
E
-
V
I
A
G
S
H
D
L
V
-
L
K
M
A
H
Q
A
D
R
L
-
E
A
V
I
F
T
P
T
D
W
H
L
L
R
K
C
P
S
P
V
W
M
V
K
D
-
Q
P
----
W
P
E
G
G
K
A
L
V
A
V
N
L
A
S
E
E
P
Y
H
N
A
L
N
E
K
L
V
K
E
T
L
Q
L
A
E
Q
V
N
H
T
E
-
V
H
L
V
G
A
Y
-
P
V
T
-
P
I
NIAIE
L
P
E
F
D
-------
P
S
V
-
Y
N
----
D
----
A
-
I
R
G
Q
H
L
L
A
M
K
A
L
R
Q
---
K
-
F
S
I
D
--
E
K
--
V
T
H
V
E
K
G
L
P
E
E
V
I
P
D
L
A
E
H
L
Q
A
G
I
V
V
L
G
T
V
G
R
T
G
L
S
A
A
F
L
G
N
T
A
E
Q
V
I
D
H
L
R
C
D
L
L
V
I
K
P
D
E
Y
Q
T
P
V
E
L
D
----
4
PsiBlast_PDB
68.50
28%
-97
- C2 -
4WY2
5
?
A:
[5-306]
-----------
E
K
Y
Q
N
L
L
V
V
I
D
P
-
N
Q
D
D
Q
P
A
L
R
R
A
----
V
Y
I
V
Q
R
N
-----
G
-
G
R
I
K
A
F
L
P
V
Y
D
LSYDMT
T
L
L
S
P
------
D
E
R
--------
N
A
M
R
K
G
V
I
N
Q
-------------------
K
----------------
T
-----------------
A
W
----
I
----
K
----
Q
Q
A
R
Y
Y
L
E
----
A
G
I
-
Q
I
---
D
I
K
--
V
-
I
W
H
N
R
P
Y
E
A
I
I
E
E
-
V
I
T
D
K
H
D
L
L
-
I
K
M
A
H
Q
H
D
K
L
-
G
S
L
I
F
T
P
L
D
W
Q
L
L
R
K
C
P
A
P
V
W
M
V
K
D
K
E
W
----
P
E
-
Y
G
T
I
V
V
A
A
N
L
S
N
E
E
S
Y
H
D
A
L
N
L
K
L
I
E
L
T
N
D
L
S
H
R
I
Q
K
D
P
D
V
H
L
L
S
A
Y
-
P
V
A
-
P
I
NIAIE
L
P
D
F
D
-------
P
N
L
-
Y
N
----
N
----
A
-
L
R
G
Q
H
L
I
A
M
K
E
L
R
Q
---
K
-
F
S
I
P
--
E
E
--
K
T
H
V
K
E
G
L
P
E
Q
V
I
P
Q
V
C
E
E
L
N
A
G
I
V
V
L
G
I
L
G
R
T
G
--
A
A
F
L
G
N
T
A
E
Q
L
I
D
H
I
K
C
D
L
L
A
I
K
P
D
G
F
T
C
P
I
T
V
-----
5
PsiBlast_PDB
67.77
27%
-97
- C2 -
3OLQ
5
?
A:
[5-306]
-----------
E
K
Y
Q
N
L
L
V
V
I
D
P
-
N
Q
D
D
Q
P
A
L
R
R
A
----
V
Y
I
V
Q
R
N
-----
G
-
G
R
I
K
A
F
L
P
V
Y
D
LSYDMT
T
L
L
S
P
------
D
E
R
--------
N
A
M
R
K
G
V
I
N
Q
-------------------
K
----------------
T
-----------------
A
W
----
I
----
K
----
Q
Q
A
R
Y
Y
L
E
----
A
G
I
-
Q
I
---
D
I
K
--
V
-
I
W
H
N
R
P
Y
E
A
I
I
E
E
-
V
I
T
D
K
H
D
L
L
-
I
K
M
A
H
Q
H
--
L
-
G
S
L
I
F
T
P
L
D
W
Q
L
L
R
K
C
P
A
P
V
W
M
V
K
D
K
E
W
----
P
E
-
Y
G
T
I
V
V
A
A
N
L
S
N
E
E
S
Y
H
D
A
L
N
L
K
L
I
E
L
T
N
D
L
S
H
R
I
Q
K
D
PD
V
H
L
L
S
A
Y
-
P
V
A
-
P
I
NIAIE
L
P
D
F
D
-------
P
N
L
-
Y
N
----
N
----
A
-
L
R
G
Q
H
L
I
A
M
K
E
L
R
Q
---
K
-
F
S
I
P
--
E
E
--
K
T
H
V
K
E
G
L
P
E
Q
V
I
P
Q
V
C
E
E
L
N
A
G
I
V
V
L
G
I
L
G
R
T
G
L
S
A
A
F
L
G
N
T
A
E
Q
L
I
D
H
I
K
C
D
L
L
A
I
K
P
D
G
F
T
C
P
I
-------
16
HHSearch
55.24
17%
-83
- C2 -
3CIS
3
Y2623_MYCTU
A:
[18-306]
------------
S
S
L
G
I
I
V
G
I
D
D
-
S
P
A
A
Q
V
A
V
R
W
A
----
A
R
D
---------
A
-
E
L
R
K
I
P
L
----------
T
L
V
H
A
------
V
S
P
--------
E
--------
V
A
T
WLEVPLP
P
G
V
L
R
W
Q
Q
D
H
G
----------------
R
-----------------
H
L
----
I
----
D
----
D
A
L
K
V
V
E
Q
A
SLR
A
G
P
P
T
V
---
H
S
E
--
I
-
V
-
P
A
A
A
V
P
T
L
V
D
M
-
S
--
K
D
A
V
L
M
-
V
V
G
C
L
G
S
G
R
W
-
P
G
R
L
L
G
S
V
S
S
G
L
L
R
H
A
H
C
P
V
V
I
I
H
D
E
D
S
VMPH
P
Q
-
Q
A
P
V
L
V
G
V
D
G
S
S
A
S
-------
E
L
A
T
A
I
A
F
D
E
A
S
R
R
N
V
D
--
L
V
A
L
H
A
W
-
S
-
D
-
V
D
-----
V
S
E
W
P
GI-----
D
W
P
A
T
Q
----
S
----
M
-
A
E
Q
V
L
A
E
R
L
A
G
W
Q
E
---
R
Y
P
N
V
---
A
I
--
T
R
V
V
V
R
D
Q
P
A
R
Q
L
V
Q
R
--
S
E
E
A
Q
L
V
V
V
G
S
R
G
R
G
G
Y
A
G
M
L
V
G
S
V
G
E
T
V
A
Q
L
A
R
T
P
V
I
V
A
R
E
--------------
33
HHSearch
53.78
16%
-96
- C2 -
3IDF
1
?
A:
[1-138]
-------------
M
K
K
L
L
F
A
I
D
D
-
T
E
A
C
E
R
A
A
Q
Y
I
----
L
D
M
---------
F
G
K
D
A
D
C
T
L
----------
T
L
I
H
V
------
K
P
E
--------
F
--------
M
-------------------
L
Y
G
E
A
V
L
A
A
Y
-------
D
E
I
E
M
K
E
E
----------
E
K
A
K
L
L
T
----
Q
----
K
F
S
T
F
F
T
E
----
K
G
I
-
N
P
---
F
V
V
--
I
-
K
-
E
G
E
P
V
E
M
V
L
E
E
-
A
K
--
D
Y
N
L
L
-
I
I
G
S
S
E
N
S
F
L
-
N
K
-
I
F
A
S
H
Q
D
D
F
I
Q
K
A
P
I
P
V
L
I
V
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
52.54
17%
-89
* C2 *
3LOQ
9
?
A:
[19-293]
----------
Y
F
Q
S
N
A
M
L
L
P
T
D
L
-
S
E
N
S
F
K
V
L
E
Y
L
----
G
D
F
---------
K
-
K
V
G
V
E
E
I
----------
G
V
L
F
V
------
I
N
L
--------
T
--------
K
LGID
I
D
H
Y
I
D
E
M
S
E
K
----
A
----------------
E
-----------------
E
V
----
L
----
P
----
E
V
A
Q
K
I
E
A
----
A
G
I
-
K
A
---
E
V
I
--
K
P
F
P
A
G
D
P
V
V
E
I
I
K
A
-
S
--
E
N
Y
S
F
I
-
A
M
G
S
R
G
A
S
K
F
-
K
K
I
L
L
G
S
V
S
E
G
V
L
H
D
S
K
V
P
V
Y
I
F
K
H
D
M
V
VN--
S
L
-
F
D
R
V
L
V
A
Y
D
F
S
K
W
A
-------
D
R
A
L
E
Y
A
K
F
V
V
K
K
T
G
G
E
--
L
H
I
I
H
V
S
-
E
-
D
-
G
D
-----
K
T
A
------------------------------
D
L
R
V
M
E
E
V
I
G
---
A
-
E
G
I
E
---
V
--
H
V
H
I
E
S
G
T
P
H
K
A
I
L
A
K
R
E
E
I
N
A
T
T
I
F
M
G
S
R
G
A
G
S
V
M
T
M
I
L
G
S
T
S
E
S
V
I
R
R
S
P
V
P
V
F
V
C
K
R
G
D
D
E
----------
17
HHSearch
52.42
18%
-93
- C2 -
3AB8
2
?
A:
[1-268]
--------------
M
R
I
L
L
A
T
D
G
-
S
P
Q
A
R
G
A
E
A
L
A
----
E
W
L
---------
A
-
Y
K
L
S
A
P
L
----------
T
V
L
F
V
------
V
D
T
--------
R
--------
L
-------------------
A
R
I
PELLP
V
P
V
L
-----
R
T
E
L
E
R
A
L
A
L
R
G
E
-----
A
V
----
L
----
E
----
R
V
R
Q
S
A
L
A
----
A
G
V
-
A
V
---
E
A
V
--
L
-
E
E
-
G
V
P
H
E
A
I
L
R
R
-
A
R
--
A
A
D
L
L
-
V
L
G
R
S
G
E
A
H
G
D
G
F
G
G
L
G
S
T
A
D
R
V
L
R
A
S
P
V
P
V
L
L
A
P
G
E
P
-----
V
E
-
L
E
G
A
L
L
G
Y
D
A
S
E
S
A
-------
V
R
A
L
H
A
L
A
P
L
A
R
A
L
G
L
G
--
V
R
V
V
S
V
H
-
E
-
D
-
P
A
-----
R
A
E
------------------------
A
-
W
----
A
L
E
A
E
A
Y
L
R
---
D
-
H
G
V
E
---
A
--
S
A
L
V
L
G
G
D
A
A
D
H
L
L
R
L
Q
--
G
P
G
D
L
L
A
L
G
A
P
----
V
R
R
L
V
F
G
S
T
A
E
R
V
I
R
N
A
Q
G
P
V
L
T
A
R
---------------
36
Fugue
51.83
16%
-82
- C2 -
2JAX
3
Y2623_MYCTU
A:
[8-294]
--------------
L
G
I
I
V
G
I
D
D
-
S
P
A
A
Q
V
A
V
R
W
A
----
A
R
D
---------
A
-
E
L
R
K
I
P
L
----------
T
L
V
H
A
V
SR
W
Q
Q
D
H
G
--------
R
--------
H
-------------------
L
----------------
I
-----------------
D
D
----
A
----
L
----
K
V
V
E
Q
A
S
L
----
R
A
G
-
P
P
---
T
V
H
--
S
-
E
I
V
P
A
A
A
V
P
T
L
V
D
M
S
K
D
A
---
V
L
M
V
V
G
C
L
G
S
G
R
W
-
P
G
R
L
L
G
S
V
S
S
G
L
L
R
H
A
H
C
P
V
V
I
I
H
-----------
D
A
P
V
L
V
G
V
D
G
S
S
A
-------
S
E
L
A
T
A
I
A
F
D
E
A
S
R
R
N
V
D
--
L
V
A
L
H
A
W
S
D
-
V
-
D
V
-----
S
E
W
P
G
-------
I
D
W
P
A
T
----
Q
----
S
M
A
E
Q
V
L
A
E
R
L
A
G
W
Q
E
---
R
-
Y
P
N
V
--
A
I
--
T
R
V
V
V
R
D
Q
P
A
R
Q
L
V
Q
R
S
E
E
A
Q
L
V
V
--
V
G
S
R
G
R
G
G
Y
A
G
M
L
V
G
S
V
G
E
T
V
A
Q
L
A
R
T
P
V
I
V
A
R
E
--------------
6
PsiBlast_PDB
47.51
23%
-100
- C2 -
4R2M
2
USPF_SALTY
A:
[19-158]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
V
P
I
D
I
S
D
S
E
L
T
Q
R
-----
V
I
S
H
V
E
A
E
A
K
I
D
D
A
K
--
V
H
F
L
T
V
I
-
P
-
S
L
P
Y
-----
Y
A
S
L
G
-------
L
A
-
S
A
E
LPA
M
D
----
D
-
L
K
A
E
A
K
S
Q
L
E
A
I
I
K
---
K
-
F
N
L
P
--
A
D
R
V
Q
A
H
V
A
E
G
S
P
K
D
K
I
L
E
M
A
K
K
L
P
A
D
M
V
I
I
A
S
-
H
R
P
D
I
T
T
Y
L
L
G
S
N
A
A
A
V
V
D
H
A
E
C
S
V
L
V
V
R
---------------
24
HHSearch
46.66
15%
-103
- C2 -
3DLO
2
?
A:
[22-155]
-----------
M
I
Y
M
P
I
V
V
A
V
D
K
K
S
D
R
A
E
R
V
L
R
F
A
----
A
E
E
---------
A
-
R
L
R
G
V
P
V
----------
Y
V
V
H
S
------
L
P
G
--------
G
--------
G
RTK
D
E
D
I
I
E
----------
A
----------------
K
-----------------
E
T
----
L
----
S
----
W
A
V
S
I
I
R
K
----
E
G
A
-
E
G
---
E
E
H
L
L
V
-
R
-
G
K
E
P
P
D
D
I
V
D
F
-
A
D
E
V
D
A
I
A
I
-
V
I
G
I
R
K
R
S
P
T
-
G
K
L
I
F
G
S
V
A
R
D
V
I
L
K
A
N
K
P
V
I
C
I
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
46.64
22%
-85
- C2 -
3TNJ
1
?
A:
[5-149]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-
Y
H
H
I
L
L
A
V
D
F
S
S
E
D
-------
S
Q
V
V
Q
K
V
R
N
L
A
S
Q
I
G
A
R
--
L
S
L
I
H
V
L
-
D
---------------YGTAIPL
D
T
E
T
T
Y
----
D
----
A
-
M
L
D
V
E
K
Q
K
L
S
Q
I
G
N
---
T
-
L
G
I
D
--
P
A
--
H
R
W
L
V
W
G
E
P
R
E
E
I
I
R
I
A
E
Q
E
N
V
D
L
I
V
V
G
S
H
---------
L
G
S
T
A
N
S
V
L
H
Y
A
K
C
D
V
L
A
V
R
L
R
D
------------
40
Fugue
46.37
17%
-63
- C2 -
3AB8
2
?
A:
[1-268]
M
R
I
L
L
A
T
DGS
P
Q
A
R
G
A
E
A
L
A
E
W
L
-
A
Y
K
L
S
A
P
L
T
V
L
----
F
V
V
D
T
R
L
A
R
I
PE
L
-
L
P
V
P
V
L
R
----------
T
E
L
E
R
------
A
L
A
--------
L
--------
R
-------------------
G
----------------
E
-----------------
A
V
----
L
----
E
----
R
V
R
Q
S
A
L
A
----
A
G
V
-
A
V
---
E
A
V
--
L
-
E
E
G
V
--
P
H
E
A
I
L
R
-
R
A
R
A
A
D
L
L
V
-
L
G
R
S
G
E
A
H
G
D
-
G
F
G
G
L
G
S
T
A
D
R
V
L
R
A
S
P
V
P
V
L
L
A
P
G
E
P
V
-----
E
-
L
E
G
A
L
L
G
Y
D
-------
A
S
E
S
A
V
R
A
L
H
A
L
A
P
L
A
R
A
L
G
L
G
--
V
R
V
V
S
V
H
-
E
-
D
-------------------------
P
----
A
----
R
-
A
E
A
W
A
L
E
A
E
A
Y
L
R
D
---
H
--
G
V
E
--
A
S
--
A
L
V
L
G
G
D
A
A
D
H
L
L
R
L
Q
G
---
P
G
D
L
L
A
L
G
A
P
V
R
----
R
L
V
F
G
S
T
A
E
R
V
I
R
N
A
Q
G
P
V
L
T
A
R
---------------
38
Fugue
45.94
16%
-84
- C2 -
1MJH
1
Y577_METJA
A:
[3-162]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
M
-
Y
K
K
I
L
Y
P
T
D
F
S
-------
E
T
A
E
I
A
L
K
H
V
K
A
F
K
T
L
K
A
E
E
--
V
I
L
L
H
V
I
-
D
-
E
-
R
E
-----
I
K
V
E
E
-------
F
E
N
E
L
K
----
N
----
K
-
L
T
E
E
A
K
N
K
M
E
N
I
K
K
---
E
-
L
E
D
V
GF
K
V
--
K
D
I
I
V
V
G
I
P
H
E
E
I
V
K
I
A
E
D
E
G
V
D
I
I
I
M
G
S
H
G
K
T
N
L
K
E
I
L
L
G
S
V
T
E
N
V
I
K
K
S
N
K
P
V
L
V
V
K
R
K
N
S
-----------
8
PsiBlast_PDB
45.66
21%
-110
- C2 -
3LOQ
8
?
A:
[173-289]
----------------
V
L
V
A
Y
D
F
-
S
K
W
A
D
R
A
L
E
Y
A
----
K
F
V
---------
V
-
K
K
T
G
G
E
L
----------
H
I
I
H
V
------
S
E
D
--------
G
--------
D
-------------------
K
----------------
T
-----------------
A
D
----
L
----
R
----
V
M
E
E
V
I
G
A
----
E
G
I
-
E
V
---
H
V
---
H
-
I
E
S
G
T
P
H
K
A
I
L
A
K
-
R
E
E
I
N
A
T
T
I
-
F
M
G
S
R
G
A
G
S
V
-
M
T
M
I
L
G
S
T
S
E
S
V
I
R
R
S
P
V
P
V
F
V
C
K
R
G
D
D
----
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
HHSearch
45.61
20%
-81
- C2 -
1MJH
1
Y577_METJA
A:
[3-161]
-----------
V
M
Y
K
K
I
L
Y
P
T
D
F
-
S
E
T
A
E
I
A
L
K
H
V
----
K
A
F
---------
K
-
T
L
K
A
E
E
V
----------
I
L
L
H
V
------
I
D
E
--------
R
--------
E
-------------------
I
----------------
K
V
E
E
F
E
N
E
L
K
N
K
L
T
E
E
A
K
N
K
----
M
----
E
----
N
I
K
K
E
L
E
D
----
V
G
F
-
K
V
---
K
D
I
--
I
-
V
-
V
G
I
P
H
E
E
I
V
K
I
-
A
E
D
E
G
V
D
I
I
-
I
M
G
S
H
G
K
T
N
L
-
K
E
I
L
L
G
S
V
T
E
N
V
I
K
K
S
N
K
P
V
L
V
V
K
R
K
N
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
45.42
17%
-77
- C2 -
1MJH
1
Y577_METJA
A:
[4-161]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
-
Y
K
K
I
L
Y
P
T
D
F
S
E
T
A
-------
E
I
A
L
K
H
V
K
A
F
K
T
L
K
A
E
E
--
V
I
L
L
H
V
I
-
D
-
E
-
R
E
-----
I
K
-----------
V
E
E
F
E
----
N
E
L
K
N
K
-
L
T
E
E
A
K
N
K
M
E
N
I
K
K
E
L
E
D
-
V
G
F
K
---
V
--
K
D
I
I
V
V
G
I
P
H
E
E
I
V
K
I
A
E
D
E
G
V
D
I
I
I
M
G
S
H
G
K
T
N
L
K
E
I
L
L
G
S
V
T
E
N
V
I
K
K
S
N
K
P
V
L
V
V
K
R
K
N
S
-----------
29
HHSearch
44.98
20%
-82
- C2 -
3HGM
3
TEAD_HALED
A:
[1-147]
------------
M
F
N
R
I
M
V
P
V
D
G
-
S
K
G
A
V
K
A
L
E
K
G
----
V
G
L
---------
Q
-
Q
L
T
G
A
E
L
----------
Y
I
L
C
V
------
F
K
H
--------
H
--------
S
-------------------
L
LEASLSMARPEQLDIP
D
-----------------
D
A
----
L
K
D
Y
A
T
E
I
A
V
Q
A
K
T
R
A
T
E
----
L
G
V
-
P
A
DK
V
R
A
F
--
V
-
K
-
G
G
R
P
S
R
T
I
V
R
F
-
A
R
K
R
E
C
D
L
V
-
V
I
G
A
Q
G
T
N
G
D
-
K
S
L
L
L
G
S
V
A
Q
R
V
A
G
S
A
H
C
P
V
L
V
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------